Guide to the Human Genome
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Search of human proteins with 6912460

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912460 GRB2-associated binding protein 2 isoform b [Homo
sapiens]
         (638 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912460 GRB2-associated binding protein 2 isoform b [Homo sap...  1298   0.0  
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa...  1298   0.0  
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa...   359   4e-99
gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa...   343   2e-94
gi|83716021 GRB2-associated binding protein family, member 4 [Ho...   306   3e-83
gi|18079323 Gab3 protein isoform 2 [Homo sapiens]                     238   1e-62
gi|126091130 Gab3 protein isoform 1 [Homo sapiens]                    234   2e-61
gi|110431370 espin [Homo sapiens]                                      49   1e-05
gi|154146216 pleckstrin homology domain containing, family A (ph...    49   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        48   3e-05
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    47   5e-05
gi|91982772 mucin 17 [Homo sapiens]                                    47   5e-05
gi|50234893 pleckstrin homology domain containing, family A (pho...    47   7e-05
gi|31377720 pleckstrin homology domain containing, family A (pho...    47   7e-05
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    44   3e-04
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]                      44   6e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        42   0.002
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         42   0.002
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             41   0.003
gi|151301154 mucin 6, gastric [Homo sapiens]                           41   0.003
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        41   0.004
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    41   0.004
gi|83367077 mucin 16 [Homo sapiens]                                    40   0.007
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    40   0.007
gi|169214023 PREDICTED: hypothetical protein [Homo sapiens]            40   0.009
gi|169214468 PREDICTED: hypothetical protein [Homo sapiens]            40   0.009
gi|39995080 hypothetical protein LOC79567 [Homo sapiens]               39   0.011
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]                39   0.015
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                39   0.019
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              38   0.025

>gi|6912460 GRB2-associated binding protein 2 isoform b [Homo
           sapiens]
          Length = 638

 Score = 1298 bits (3358), Expect = 0.0
 Identities = 638/638 (100%), Positives = 638/638 (100%)

Query: 1   MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV 60
           MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV
Sbjct: 1   MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV 60

Query: 61  AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS 120
           AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS
Sbjct: 61  AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS 120

Query: 121 SAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRAS 180
           SAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRAS
Sbjct: 121 SAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRAS 180

Query: 181 FLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHT 240
           FLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHT
Sbjct: 181 FLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHT 240

Query: 241 KGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNA 300
           KGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNA
Sbjct: 241 KGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNA 300

Query: 301 MTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNS 360
           MTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNS
Sbjct: 301 MTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNS 360

Query: 361 RLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG 420
           RLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG
Sbjct: 361 RLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG 420

Query: 421 SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLK 480
           SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLK
Sbjct: 421 SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLK 480

Query: 481 PDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSG 540
           PDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSG
Sbjct: 481 PDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSG 540

Query: 541 DSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSD 600
           DSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSD
Sbjct: 541 DSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSD 600

Query: 601 EKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL 638
           EKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL
Sbjct: 601 EKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL 638


>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
           sapiens]
          Length = 676

 Score = 1298 bits (3358), Expect = 0.0
 Identities = 638/638 (100%), Positives = 638/638 (100%)

Query: 1   MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV 60
           MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV
Sbjct: 39  MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV 98

Query: 61  AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS 120
           AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS
Sbjct: 99  AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS 158

Query: 121 SAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRAS 180
           SAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRAS
Sbjct: 159 SAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRAS 218

Query: 181 FLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHT 240
           FLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHT
Sbjct: 219 FLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHT 278

Query: 241 KGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNA 300
           KGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNA
Sbjct: 279 KGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNA 338

Query: 301 MTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNS 360
           MTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNS
Sbjct: 339 MTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNS 398

Query: 361 RLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG 420
           RLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG
Sbjct: 399 RLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG 458

Query: 421 SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLK 480
           SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLK
Sbjct: 459 SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLK 518

Query: 481 PDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSG 540
           PDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSG
Sbjct: 519 PDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSG 578

Query: 541 DSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSD 600
           DSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSD
Sbjct: 579 DSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSD 638

Query: 601 EKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL 638
           EKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL
Sbjct: 639 EKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL 676


>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
           sapiens]
          Length = 694

 Score =  359 bits (922), Expect = 4e-99
 Identities = 256/684 (37%), Positives = 356/684 (52%), Gaps = 77/684 (11%)

Query: 1   MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV 60
           ++GDPDVLEYYKNDH+KKP+RII+LN C+QVDAGLTFNKKE ++S++FDI T +R FYLV
Sbjct: 38  LTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLV 97

Query: 61  AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS 120
           A++EE+MNKWV+ IC ICGFN  EE  D ++   S+   P   P  ++           +
Sbjct: 98  ADSEEEMNKWVRCICDICGFNPTEE--DPVKPPGSSLQAPADLPLAIN-----------T 144

Query: 121 SAPSHSSQPTLFTFEPP-----VSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQ 175
           + PS  +  +  T  PP     V  H++       PQ+YL L  C S++ E  R+ + S 
Sbjct: 145 APPSTQADSSSATLPPPYQLINVPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSA 204

Query: 176 GTRASFLMRSDTAVQKLAQGNGHCVNGISG--QVHGFYSLPKPSRHNTEFRDSTYDLPRS 233
            + +S    +D         +    +G++G  Q    Y  P     +     S Y+LPRS
Sbjct: 205 KSTSSETDCNDNVPSHKNPASSQSKHGMNGFFQQQMIYDSPPSRAPSASVDSSLYNLPRS 264

Query: 234 LASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVD-NMDVPATPLSAYQIPRTF 292
            +     K S + +E D E +Y F TPS T   E     V  + D+P TP + YQIPRTF
Sbjct: 265 YSHDVLPKVSPSSTEADGE-LYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTF 323

Query: 293 ---TLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAAT-- 347
              TL +     T+         PPPRPPKP  A      SP +   I   +    ++  
Sbjct: 324 PEGTLGQTSKLDTIPD------IPPPRPPKPHPAHD---RSPVETCSIPRTASDTDSSYC 374

Query: 348 IP-------RRNTLPAMDNSRLHR-ASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGK 399
           IP       R NT+  +D ++L + ASS + Y+ P+        S E   +     +   
Sbjct: 375 IPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFK--VKNV 432

Query: 400 MIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSV-YIPMSPGAHHFDS-------- 450
           + VG   S   ++NYVPMNP S          +  Q   Y+PM+PG   F S        
Sbjct: 433 LTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPP 492

Query: 451 --LGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDEL--PFKSP 506
             +G+ S+     R P   ++ +PPPV+RNLKPDRK KP PL+++     +EL  P +SP
Sbjct: 493 AHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKVKPAPLEIKPLPEWEELQAPVRSP 552

Query: 507 ITKSWSRANHTFNSSSSQYCRPISTQSIT-STDSGDSEENYVPMQNPVSASPVPS----- 560
           IT+S++R +  F  S     RP S  S T S+DS DSEENYVPM NP  +S  P+     
Sbjct: 553 ITRSFARDSSRFPMSP----RPDSVHSTTSSSDSHDSEENYVPM-NPNLSSEDPNLFGSN 607

Query: 561 ---GTNSPAPK-KSTGSVDYLALDFQPSSPSPHRKPSTS---SVTSDEKVDYVQVDKEKT 613
              G +SP  K K    V+YL LD      +P RK  +S   S  +DE+VDYV VD++KT
Sbjct: 608 SLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERVDYVVVDQQKT 667

Query: 614 QALQNTMQEWTDVRQSSEPSKGAK 637
            AL++T + WTD RQS+E    AK
Sbjct: 668 LALKSTREAWTDGRQSTESETPAK 691


>gi|46370071 GRB2-associated binding protein 1 isoform a [Homo
           sapiens]
          Length = 724

 Score =  343 bits (881), Expect = 2e-94
 Identities = 256/714 (35%), Positives = 356/714 (49%), Gaps = 107/714 (14%)

Query: 1   MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV 60
           ++GDPDVLEYYKNDH+KKP+RII+LN C+QVDAGLTFNKKE ++S++FDI T +R FYLV
Sbjct: 38  LTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLV 97

Query: 61  AETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKS 120
           A++EE+MNKWV+ IC ICGFN  EE  D ++   S+   P   P  ++           +
Sbjct: 98  ADSEEEMNKWVRCICDICGFNPTEE--DPVKPPGSSLQAPADLPLAIN-----------T 144

Query: 121 SAPSHSSQPTLFTFEPP-----VSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQ 175
           + PS  +  +  T  PP     V  H++       PQ+YL L  C S++ E  R+ + S 
Sbjct: 145 APPSTQADSSSATLPPPYQLINVPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSA 204

Query: 176 GTRASFLMRSDTAVQKLAQGNGHCVNGISG--QVHGFYSLPKPSRHNTEFRDSTYDLPRS 233
            + +S    +D         +    +G++G  Q    Y  P     +     S Y+LPRS
Sbjct: 205 KSTSSETDCNDNVPSHKNPASSQSKHGMNGFFQQQMIYDSPPSRAPSASVDSSLYNLPRS 264

Query: 234 LASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVD-NMDVPATPLSAYQIPRTF 292
            +     K S + +E D E +Y F TPS T   E     V  + D+P TP + YQIPRTF
Sbjct: 265 YSHDVLPKVSPSSTEADGE-LYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTF 323

Query: 293 ---TLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAAT-- 347
              TL +     T+         PPPRPPKP  A      SP +   I   +    ++  
Sbjct: 324 PEGTLGQTSKLDTIPD------IPPPRPPKPHPAHD---RSPVETCSIPRTASDTDSSYC 374

Query: 348 IP-------RRNTLPAMDNSRLHR-ASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGK 399
           IP       R NT+  +D ++L + ASS + Y+ P+        S E   +     +   
Sbjct: 375 IPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFK--VKNV 432

Query: 400 MIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSV-YIPMSPGAHHFDS-------- 450
           + VG   S   ++NYVPMNP S          +  Q   Y+PM+PG   F S        
Sbjct: 433 LTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPP 492

Query: 451 --LGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPD-------------------------- 482
             +G+ S+     R P   ++ +PPPV+RNLKPD                          
Sbjct: 493 AHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKGQSPKILRLKPHGLERTDSQTIGD 552

Query: 483 ----RKAKPTPLDLRNNTVIDEL--PFKSPITKSWSRANHTFNSSSSQYCRPISTQSIT- 535
               RK KP PL+++     +EL  P +SPIT+S++R +  F  S     RP S  S T 
Sbjct: 553 FATRRKVKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSP----RPDSVHSTTS 608

Query: 536 STDSGDSEENYVPMQNPVSASPVPS--------GTNSPAPK-KSTGSVDYLALDFQPSSP 586
           S+DS DSEENYVPM NP  +S  P+        G +SP  K K    V+YL LD      
Sbjct: 609 SSDSHDSEENYVPM-NPNLSSEDPNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKS 667

Query: 587 SPHRKPSTS---SVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAK 637
           +P RK  +S   S  +DE+VDYV VD++KT AL++T + WTD RQS+E    AK
Sbjct: 668 TPPRKQKSSGSGSSVADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPAK 721


>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
           sapiens]
          Length = 574

 Score =  306 bits (785), Expect = 3e-83
 Identities = 162/253 (64%), Positives = 190/253 (75%), Gaps = 15/253 (5%)

Query: 2   SGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLT--FNKKELQDSFVFDIKTSERTFYL 59
           S DPDVLEYYKND SKKPLR INLN CEQ+D  +T  FNKKE+Q  ++FDIKTSERTFYL
Sbjct: 73  SSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYL 132

Query: 60  VAETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERK 119
           VAET EDMN+WVQSICQICGF Q EEST  L N+SSA HG  SSPAE S S QHL +E++
Sbjct: 133 VAETREDMNEWVQSICQICGFRQ-EESTGFLGNISSASHGLCSSPAEPSCSHQHLPQEQE 191

Query: 120 SSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRA 179
                        T EPPVS+ + PT    AP   L  HQ  S+RAE+ARSASFSQG+ A
Sbjct: 192 P------------TSEPPVSHCVPPTWPIPAPPGCLRSHQHASQRAEHARSASFSQGSEA 239

Query: 180 SFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGH 239
            F+MR +TA+Q LAQ +G+ V+G+SG +HGF+SL KPS+HN EFR ST+ +P SLASHGH
Sbjct: 240 PFIMRRNTAMQNLAQHSGYSVDGVSGHIHGFHSLSKPSQHNAEFRGSTHRIPWSLASHGH 299

Query: 240 TKGSLTGSETDNE 252
           T+GSLTGSE DNE
Sbjct: 300 TRGSLTGSEADNE 312



 Score =  295 bits (755), Expect = 9e-80
 Identities = 161/267 (60%), Positives = 195/267 (73%), Gaps = 9/267 (3%)

Query: 372 EYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAG 431
           +Y Q GG +A R AESM +GV SFLPG+ +VG SDS  SE + VPMNPGS TL A+++AG
Sbjct: 317 KYTQHGGGNASRPAESMHEGVCSFLPGRTLVGLSDSIASEGSCVPMNPGSPTLPAVKQAG 376

Query: 432 DNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLD 491
           D+SQ V IP+      FD LG P T L +H+  S+G E+Q PPVNR+LKP++KA PTP +
Sbjct: 377 DDSQGVCIPVGSCLVRFDLLGSPLTELSMHQDLSQGHEVQLPPVNRSLKPNQKANPTPPN 436

Query: 492 LRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQN 551
           LRNN VI+EL FK P+T+ WS  +HTF+SSSSQ+  PISTQSIT+TDS DS E Y+   N
Sbjct: 437 LRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQH--PISTQSITNTDSEDSGERYL-FPN 493

Query: 552 PVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKE 611
           P SA PV  GT+S AP +STG++ Y ALDFQPS      KPS  SVTS +KVDYVQVD E
Sbjct: 494 PASAFPVSGGTSSSAPPRSTGNIHYAALDFQPS------KPSIGSVTSGKKVDYVQVDLE 547

Query: 612 KTQALQNTMQEWTDVRQSSEPSKGAKL 638
           KTQALQ TM E   +RQSSEP +GAKL
Sbjct: 548 KTQALQKTMHEQMCLRQSSEPPRGAKL 574


>gi|18079323 Gab3 protein isoform 2 [Homo sapiens]
          Length = 586

 Score =  238 bits (608), Expect = 1e-62
 Identities = 198/640 (30%), Positives = 306/640 (47%), Gaps = 104/640 (16%)

Query: 1   MSGDPDVLEYYKNDHSKKPLRIINLNFCEQ-VDAGLTFNKKELQDSFVFDIKTSERTFYL 59
           MSG+PDVLEYY+N HS KP+R+I+L+ C      G +F +KE Q++FVF +KT+ RTFYL
Sbjct: 38  MSGNPDVLEYYRNKHSSKPIRVIDLSECAVWKHVGPSFVRKEFQNNFVFIVKTTSRTFYL 97

Query: 60  VAETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERK 119
           VA+TE++M  WV SI Q+C     E+  DS+ ++S        +P+ L  SS        
Sbjct: 98  VAKTEQEMQVWVHSISQVCNLGHLEDGADSMESLSY-------TPSSLQPSSA------S 144

Query: 120 SSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQ-CISRRAENARSASFSQGTR 178
           S   +H++  +L   +P  + +   T  T +  E L+L    +    E  R    S  TR
Sbjct: 145 SLLTAHAASSSLPRDDP--NTNAVATEETRSESELLFLPDYLVLSNCETGRLHHTSLPTR 202

Query: 179 ASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHG 238
                 SD ++++ +                          +  F D    LP S   H 
Sbjct: 203 CDSWSNSDRSLEQAS-------------------------FDDVFVDCLQPLPSSHLVHP 237

Query: 239 HTKGSLTGSETDNEDVYTFKTPSNTL-CREFGDLLVDNMDVPATPLSAYQIPRTFTLDKN 297
              GS        ++V + +  +  +  RE      D++   ++PL    +  T  +DKN
Sbjct: 238 SCHGS------GAQEVPSSRPQAALIWSREINGPPRDHLS--SSPLLESSLSSTIQVDKN 289

Query: 298 HNAMTVATPGDSAIA--PPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLP 355
             ++         ++  PPPRPPKPS     R    ++    S + +     +PRR +L 
Sbjct: 290 QGSLPCGAKELDIMSNTPPPRPPKPSHLSERR---QEEWSTHSGSKKPECTLVPRRISLS 346

Query: 356 AMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMI-VGRSDSTNSEDNY 414
            +DN R  +A             +  G+S       +   LP +   +  + S + ED+Y
Sbjct: 347 GLDNMRTWKA-------------DVEGQSLRHRDKRLSLNLPCRFSPMYPTASASIEDSY 393

Query: 415 VPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPP 474
           VPM+P +    A       S   YIPM+ G     S+  P   LP +        ++PPP
Sbjct: 394 VPMSPQAG---ASGLGPHCSPDDYIPMNSG-----SISSPLPELPAN--------LEPPP 437

Query: 475 VNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPI----- 529
           VNR+LKP RK++P PLDLRN ++I E    + +T++      T   S + +  P      
Sbjct: 438 VNRDLKPQRKSRPPPLDLRNLSIIRE---HASLTRT-----RTVPCSRTSFLSPERNGIN 489

Query: 530 STQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPH 589
           S +   +  S + EE+Y+ M+   +AS + SG  +   K S   +DYLALDF  +SP+P 
Sbjct: 490 SARFFANPVSREDEESYIEMEEHRTASSLSSGALTWTKKFS---LDYLALDFNSASPAPM 546

Query: 590 RKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQS 629
           ++    S   +++VDYVQVD++KTQALQ+T QEWTD RQS
Sbjct: 547 QQKLLLS--EEQRVDYVQVDEQKTQALQSTKQEWTDERQS 584


>gi|126091130 Gab3 protein isoform 1 [Homo sapiens]
          Length = 587

 Score =  234 bits (597), Expect = 2e-61
 Identities = 198/641 (30%), Positives = 307/641 (47%), Gaps = 105/641 (16%)

Query: 1   MSGDPDVLEYYKNDHSKKPLRIINLNFCEQ-VDAGLTFNKKELQDSFVFDIKTSERTFYL 59
           MSG+PDVLEYY+N HS KP+R+I+L+ C      G +F +KE Q++FVF +KT+ RTFYL
Sbjct: 38  MSGNPDVLEYYRNKHSSKPIRVIDLSECAVWKHVGPSFVRKEFQNNFVFIVKTTSRTFYL 97

Query: 60  VAETEEDMNKWVQSICQICGFNQAEE-STDSLRNVSSAGHGPRSSPAELSSSSQHLLRER 118
           VA+TE++M  WV SI Q+C     E+ + DS+ ++S        +P+ L  SS       
Sbjct: 98  VAKTEQEMQVWVHSISQVCNLGHLEDGAADSMESLSY-------TPSSLQPSSA------ 144

Query: 119 KSSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQ-CISRRAENARSASFSQGT 177
            S   +H++  +L   +P  + +   T  T +  E L+L    +    E  R    S  T
Sbjct: 145 SSLLTAHAASSSLPRDDP--NTNAVATEETRSESELLFLPDYLVLSNCETGRLHHTSLPT 202

Query: 178 RASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASH 237
           R      SD ++++ +                          +  F D    LP S   H
Sbjct: 203 RCDSWSNSDRSLEQAS-------------------------FDDVFVDCLQPLPSSHLVH 237

Query: 238 GHTKGSLTGSETDNEDVYTFKTPSNTL-CREFGDLLVDNMDVPATPLSAYQIPRTFTLDK 296
               GS        ++V + +  +  +  RE      D++   ++PL    +  T  +DK
Sbjct: 238 PSCHGS------GAQEVPSSRPQAALIWSREINGPPRDHLS--SSPLLESSLSSTIQVDK 289

Query: 297 NHNAMTVATPGDSAIA--PPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTL 354
           N  ++         ++  PPPRPPKPS     R    ++    S + +     +PRR +L
Sbjct: 290 NQGSLPCGAKELDIMSNTPPPRPPKPSHLSERR---QEEWSTHSGSKKPECTLVPRRISL 346

Query: 355 PAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMI-VGRSDSTNSEDN 413
             +DN R  +A             +  G+S       +   LP +   +  + S + ED+
Sbjct: 347 SGLDNMRTWKA-------------DVEGQSLRHRDKRLSLNLPCRFSPMYPTASASIEDS 393

Query: 414 YVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPP 473
           YVPM+P +    A       S   YIPM+ G     S+  P   LP +        ++PP
Sbjct: 394 YVPMSPQAG---ASGLGPHCSPDDYIPMNSG-----SISSPLPELPAN--------LEPP 437

Query: 474 PVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPI---- 529
           PVNR+LKP RK++P PLDLRN ++I E    + +T++      T   S + +  P     
Sbjct: 438 PVNRDLKPQRKSRPPPLDLRNLSIIRE---HASLTRT-----RTVPCSRTSFLSPERNGI 489

Query: 530 -STQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSP 588
            S +   +  S + EE+Y+ M+   +AS + SG  +   K S   +DYLALDF  +SP+P
Sbjct: 490 NSARFFANPVSREDEESYIEMEEHRTASSLSSGALTWTKKFS---LDYLALDFNSASPAP 546

Query: 589 HRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQS 629
            ++    S   +++VDYVQVD++KTQALQ+T QEWTD RQS
Sbjct: 547 MQQKLLLS--EEQRVDYVQVDEQKTQALQSTKQEWTDERQS 585


>gi|110431370 espin [Homo sapiens]
          Length = 854

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 66/294 (22%), Positives = 105/294 (35%), Gaps = 34/294 (11%)

Query: 313 PPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHR-ASSCETY 371
           PPP PP  +Q   P  G P  +PP+   +  +   +  +N L  ++   L +  SSC+ +
Sbjct: 438 PPPPPPPGTQLPPPPPGYPAPKPPVGPQAADI--YMQTKNKLRHVETEALKKELSSCDGH 495

Query: 372 EYPQRGGESAGRSAESMSDGVGSF------LPGKMIVGRSDSTNSEDNYVPMNPGSSTLL 425
           +  +R   S    A S     G +       PG+ +  R    +SE+    +        
Sbjct: 496 DGLRRQDSSRKPRAFSKQPSTGDYYRQLGRCPGETLAARPGMAHSEE----VRARQPARA 551

Query: 426 AMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKA 485
              R G        P + G+    S    +  LP +  P+  +    P  +R L P    
Sbjct: 552 GCPRLG--------PAARGSLEGPSAPPQAALLPGNHVPNGCA--ADPKASRELPPPPPP 601

Query: 486 KPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEEN 545
            P PL    ++     P   P+  +        +SSS+   +  +  S T    GD+ E 
Sbjct: 602 PPPPLPEAASSPPPAPPL--PLESAGPGCGQRRSSSSTGSTKSFNMMSPT----GDNSEL 655

Query: 546 YVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTS 599
              ++   S  P P            G        FQP SP P   P+ S V S
Sbjct: 656 LAEIKAGKSLKPTPQSKGLTTVFSGIGQP-----AFQPDSPLPSVSPALSPVRS 704



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 29/118 (24%), Positives = 40/118 (33%), Gaps = 21/118 (17%)

Query: 258 KTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNH--NAMTVATPGDSAIAPPP 315
           + P+   C   G     +++ P+ P      P+   L  NH  N           + PPP
Sbjct: 546 RQPARAGCPRLGPAARGSLEGPSAP------PQAALLPGNHVPNGCAADPKASRELPPPP 599

Query: 316 RPPKPSQAETPRWGSPQQRPPI-----------SENSRSVAATIPRRNTLPAMDNSRL 362
            PP P   E     SP   PP+             +S S  +T       P  DNS L
Sbjct: 600 PPPPPPLPEAA--SSPPPAPPLPLESAGPGCGQRRSSSSTGSTKSFNMMSPTGDNSEL 655


>gi|154146216 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 2 [Homo
           sapiens]
          Length = 425

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 41/146 (28%), Positives = 65/146 (44%), Gaps = 6/146 (4%)

Query: 10  YYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNK 69
           Y+K +  ++PLR I L    +    L  +   L    +F+I TS RTFY+ A++ EDM+ 
Sbjct: 229 YFKCEQDREPLRTIFLKDVLKTHECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHS 288

Query: 70  WVQSI-CQICGFNQAEESTDSLRNVSSAGHGP---RSSPAELSSSSQHLLRERKS--SAP 123
           W++ I   +         T   R++S    G     S P  +    +  L E+K+   AP
Sbjct: 289 WIKEIGAAVQALKCHPRETSFSRSISLTRPGSSSLSSGPNSILCRGRPPLEEKKALCKAP 348

Query: 124 SHSSQPTLFTFEPPVSNHMQPTLSTS 149
           S +S    +T  P     + P   TS
Sbjct: 349 SVASSWQPWTPVPQAGEKLLPPGDTS 374


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 99/419 (23%), Positives = 150/419 (35%), Gaps = 57/419 (13%)

Query: 216  PSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDN 275
            PS   T    ++ +L    ++H     ++ GS T           S T  R    L   N
Sbjct: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRT----AAALAPASLTSARMAPALSGAN 2379

Query: 276  MDVPATPLSAYQIPRTFT----LDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWG-S 330
            +  P  PLSAY+     T    LD+  +    + P  S +    R P PS     R G +
Sbjct: 2380 LTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSE-RAPSPSS----RMGQA 2434

Query: 331  PQQR--PPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESM 388
            P Q   PP  +  RS   +          D SR   A +      P  G +S    A + 
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSA-------FSDQSRCLIAQTT-----PVAGSQSLSSGAVAT 2482

Query: 389  SDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGS---STLLAMERAGDN-SQSVYIPMSPG 444
            +        G + V      +S+    P + G+   S L A++ A +  S S     S  
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542

Query: 445  AHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLD---LRNNTVIDEL 501
            +    S    S++       S GS +   PV   +   R   PTP     +R     +  
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSL---PVQPEVALKRVPSPTPAPKEAVREGRPPEPT 2599

Query: 502  PFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSG 561
            P K    +S S ++ + +SSSS      S+ S +S+ S  S  +     +P  A P P  
Sbjct: 2600 PAKRK-RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658

Query: 562  TNSPA--------------PKKSTGSV-DYLALDFQP---SSPSPHRKPSTSSVTSDEK 602
               PA              P+K   S+ D  +L + P     PSP   P     +S E+
Sbjct: 2659 LPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 60/274 (21%), Positives = 90/274 (32%), Gaps = 24/274 (8%)

Query: 295 DKNHNAMTVATPGDSAIAPPPRPPKPSQAETPR-WGSPQQRPPISENSRSVAATIPRRNT 353
           DK   + T  +P     +  P PP P+     R  GSPQ   P++    S     P    
Sbjct: 341 DKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ---PLATTPLSQEPVNPPSEA 397

Query: 354 LPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDN 413
            P  D S             P +  E   +S+ S S       P    V R  S++ E  
Sbjct: 398 SPTRDRS-------------PPKSPEKLPQSSSSESSPPS---PQPTKVSRHASSSPESP 441

Query: 414 YVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDS--LGYPSTTLPVHRGPSRGSEIQ 471
                PGS   ++      N             H  S  +G   +     RG SR     
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501

Query: 472 PPPVNRNLKPD-RKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPIS 530
               +R+  P  R+++      R+ +       +SP    WSR+ +T     S+  R   
Sbjct: 502 KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGR 561

Query: 531 TQSITSTDSGDSEENYVPMQNPVSASPVPSGTNS 564
           + S +    G S     P +   S S  P+   S
Sbjct: 562 SHSRSPATRGRSRSR-TPARRGRSRSRTPARRRS 594



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 106/516 (20%), Positives = 182/516 (35%), Gaps = 66/516 (12%)

Query: 81   NQAEESTDSLRNVSSAGHGPRSSPA--ELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPV 138
            +QA      + +++S+  GP  SP   ELS+S    LRE    +P        F    P+
Sbjct: 1289 SQASLEAVEVPSMASSWGGPHFSPEHKELSNSP---LRENSFGSPLE------FRNSGPL 1339

Query: 139  SNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFS-QGTRASFLMRSDTAVQKLAQGNG 197
               M    S+   ++   L+     + E   S     Q TR+S    S+ +   + +   
Sbjct: 1340 GTEMNTGFSSEVKED---LNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGM 1396

Query: 198  HCVNGISGQVHGFYSLPK-PSRHNT------EFRDSTYDLPRSLASHGHTKG-------- 242
                 IS  V    ++P+ PSR  +      E +D     P   +  G + G        
Sbjct: 1397 SSNQSISSPV--LDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454

Query: 243  ---SLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHN 299
               SL+GS    +D+   +TPS    R   D   +   +P TP    + P +  L+    
Sbjct: 1455 SRHSLSGSSPGMKDIP--RTPSRG--RSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL 1510

Query: 300  AMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQ---RPPISENSRSVAATIPRRNTLPA 356
                   G  +        +    +  R GS Q+   +P  S   RS + + P       
Sbjct: 1511 TPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTR 1570

Query: 357  MDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVP 416
                +  R+ S    +   R      RS  S        +  K        + S+ +  P
Sbjct: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE------VKDKPRAAPRAQSGSDSSPEP 1624

Query: 417  MNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVN 476
              P    L    R+G +S+       P      S        P  R   RGS   P P  
Sbjct: 1625 KAPAPRALPRRSRSGSSSKG----RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680

Query: 477  RNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITS 536
            ++  P R+        R++    EL  K+ +++    A+ +  + S    R   + S++S
Sbjct: 1681 KSRTPPRR--------RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS 1732

Query: 537  TDSGDSEENYVPMQNPVSASPVPSGTN----SPAPK 568
             +   +E++    +   ++SP    T+    SP+PK
Sbjct: 1733 PE--PAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 56/229 (24%), Positives = 83/229 (36%), Gaps = 34/229 (14%)

Query: 351 RNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNS 410
           R+T PA  + R HR++S ++         S+  ++ S S    +      + GRS S  S
Sbjct: 249 RSTTPAPKSRRAHRSTSADS--------ASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS 300

Query: 411 ----EDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSR 466
               E +     PG++   + +R      +   P SP           S T P    P R
Sbjct: 301 GRRGEGDAPFSEPGTT---STQRPSSPETATKQPSSPYEDKDKDKKEKSATRP-SPSPER 356

Query: 467 GSEIQPPPVNRNLKPDRK-AKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQY 525
            S    PP    L  +R    P PL     T + + P   P     S A+ T + S    
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQPL---ATTPLSQEPVNPP-----SEASPTRDRSP--- 405

Query: 526 CRPISTQSITSTDSGDSEENYVPMQNPVSAS-PVPSGTNSPAPKKSTGS 573
             P S + +  + S +S     P   P   S    S   SP P  + GS
Sbjct: 406 --PKSPEKLPQSSSSESSP---PSPQPTKVSRHASSSPESPKPAPAPGS 449


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 79/319 (24%), Positives = 117/319 (36%), Gaps = 37/319 (11%)

Query: 288 IPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAAT 347
           +P T +L K  +  ++ T   S  +P   PP+ S   +P   S    P  +   R+    
Sbjct: 196 MPSTASLTKMDSTASI-TRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRA 254

Query: 348 IPR----RNTLPAMDNSRLHRASSCETYEYPQRGGESA--GRSAESMSDGVGSFLPGKMI 401
            P     R +L  MD++    AS   T   P     +    R++ SM+    S +    +
Sbjct: 255 SPTGMLSRTSLTKMDST----ASITRTPSRPSTASPTGTPSRASLSMTPSTASLM---RM 307

Query: 402 VGRSDSTN--SEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLP 459
           + R+  T   S  +   M+  +S      RA        I  +P        G PST  P
Sbjct: 308 LPRASPTGMLSRTSLTKMDSTASISRTPPRAS-------ITRTPS--RASPTGKPSTASP 358

Query: 460 VHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFN 519
               PSR S    P           A PT    R +      P  + +T+   RA+ T  
Sbjct: 359 TGT-PSRASPTGSPSTASLTGLSSTASPTGTPPRASPT--GTPSTASLTRKPPRASPT-- 413

Query: 520 SSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLAL 579
                    +S  SIT  DS  S     P  +P    P  S T +P+    TG+    + 
Sbjct: 414 -------GMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASP 466

Query: 580 DFQPSSPSPHRKPSTSSVT 598
              PS+ SP   PST+S T
Sbjct: 467 TGSPSTASPTGSPSTASPT 485



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 75/311 (24%), Positives = 111/311 (35%), Gaps = 39/311 (12%)

Query: 309 SAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATI---------PRRNTLPAMDN 359
           S  +P   PP+ S   TP   S  ++PP +  +  ++ T          P R    A   
Sbjct: 381 STASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPT 440

Query: 360 SRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNP 419
               RAS   T   P R   +  +S  S +    +  P       S + +     +   P
Sbjct: 441 GTPPRASPTGT---PSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTP 497

Query: 420 GSSTLLAME------RAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPP 473
             ++L  ME      R    +   + P +         G PST L +   PSR +  + P
Sbjct: 498 SRASLTKMESTASITRTPSRASPTWTPSTASP-----TGSPSTALAMG-SPSRAALTRTP 551

Query: 474 P-VNRNLKPDRKAKPTP----LDLRNNTVI-DELPFKSPITKSWSRANHTFNSSSSQYCR 527
              +    P R +  TP    L    +TV+   +P  +  T   SR + T   SS+   +
Sbjct: 552 SRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTK 611

Query: 528 PISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPS 587
             ST SIT T    S     P  +P    P  S T +P     TG+         P   S
Sbjct: 612 MDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPPRASPTGT---------PPRAS 662

Query: 588 PHRKPSTSSVT 598
           P   PS +S T
Sbjct: 663 PTGTPSRASPT 673



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 86/347 (24%), Positives = 120/347 (34%), Gaps = 39/347 (11%)

Query: 278 VPATPLSAYQIPRTFTLDK-NHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPP 336
           +P+T L     PR       +  ++T      S    P RP   S   TP   S    P 
Sbjct: 241 MPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPS 300

Query: 337 ISENSRSVAATIPR----RNTLPAMDNSRL-----HRASSCETYEYPQRGGESAGRS--- 384
            +   R +    P     R +L  MD++        RAS   T       G+ +  S   
Sbjct: 301 TASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTG 360

Query: 385 AESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNP--GSSTLLAMERAGDNSQSVYIPMS 442
             S +   GS  P    +    ST S     P     G+ +  ++ R    +    +   
Sbjct: 361 TPSRASPTGS--PSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSR 418

Query: 443 PGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPT-------PLDLRNN 495
                 DS   P+ T      P R S    PP         +A PT       P    + 
Sbjct: 419 TSITKMDSTASPTRT------PPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPST 472

Query: 496 TVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSA 555
                 P  +  T S SRA+ T   S +   +  ST SIT T S  S     P   P +A
Sbjct: 473 ASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRAS-----PTWTPSTA 527

Query: 556 SPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEK 602
           SP    T SP+   + GS    AL   PS  S  R PS +S+T+  +
Sbjct: 528 SP----TGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSR 570



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 38/136 (27%), Positives = 55/136 (40%), Gaps = 4/136 (2%)

Query: 464 PSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSS 523
           PSR S    P     L    +A  T    R +  +   P  + +T++  RA+ T   S +
Sbjct: 134 PSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMT--PSTASLTRTPPRASPTGMPSRT 191

Query: 524 QYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQ- 582
                 ST S+T  DS  S    +   +P    P  S T SP P+ S   +   AL  + 
Sbjct: 192 SPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSP-PRASLSMMPSTALLIRT 250

Query: 583 PSSPSPHRKPSTSSVT 598
           P   SP    S +S+T
Sbjct: 251 PPRASPTGMLSRTSLT 266



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 9/97 (9%)

Query: 502 PFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSG 561
           P  + +T+S SRA+ T   S +      ST +  +  S  S     P  +        S 
Sbjct: 116 PSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASL 175

Query: 562 TNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVT 598
           T +P     TG          PS  SP   PST+S+T
Sbjct: 176 TRTPPRASPTG---------MPSRTSPTGMPSTASLT 203


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 84/375 (22%), Positives = 136/375 (36%), Gaps = 59/375 (15%)

Query: 281  TPLSAYQIPRTFTLDKNHNAMTVATPGDS---------AIAPPPRPP-------KPSQAE 324
            TPL++  +  T  +    N ++  TP DS         A +PPP           P +  
Sbjct: 1160 TPLASMPVSTTLVVSSEANTLST-TPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERS 1218

Query: 325  TPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRS 384
            TP    P +  P++ +  S  +T P   + P          +S ET   P     + G S
Sbjct: 1219 TPLTSMPVRHTPVASSEASTLSTSPVDTSTPV--------TTSAETSSSPT---TAEGTS 1267

Query: 385  AESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLA--MERAGDNSQSVYIPMS 442
              + +   GS L   + V  +  T         +P +STLL   ++  G    S  +  S
Sbjct: 1268 LPTSTTSEGSTLLTSIPVSTTLVT---------SPEASTLLTTPVDTKGPVVTSNEVSSS 1318

Query: 443  PGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRK---AKPTPLDLRNNTVID 499
            P      S+  P++T    R P     +   PVN  L           TP+D        
Sbjct: 1319 PTPAEGTSM--PTSTYSEGRTP-----LTSIPVNTTLVASSAISILSTTPVDNSTPVTTS 1371

Query: 500  ELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVP 559
                 SP T   S      NS+ S+   P+++  +++T    SE       + +SA+PV 
Sbjct: 1372 TEACSSPTT---SEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSE------ASTLSATPVD 1422

Query: 560  SGTNSPAPKKSTGS-VDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQN 618
            + T      ++T S      +    S+PS  + P  S   S+  V   +     T  + +
Sbjct: 1423 TSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDS 1482

Query: 619  TMQEWTDVRQSSEPS 633
                 T    SS P+
Sbjct: 1483 NSPVVTSTAVSSSPT 1497



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 80/400 (20%), Positives = 133/400 (33%), Gaps = 47/400 (11%)

Query: 245 TGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVA 304
           T SE  +       T   T     G   + +M V  TP+++ +     T   +     V 
Sbjct: 426 TASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQ-VT 484

Query: 305 TPGDSAIAPPPRPPK------PSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMD 358
           T  +++ +PP           PS+  TP         P++ +  S  +T P   + P   
Sbjct: 485 TSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTT 544

Query: 359 NSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMN 418
           +S    ASS  T           G S  + +   GS     M V      +SE +     
Sbjct: 545 SS---EASSSST--------TPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTT 593

Query: 419 PGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRN 478
           P  S       +  +S S                   T++P      RG+ I    V+  
Sbjct: 594 PADSNTFVTTSSEASSSSTTA--------------EGTSMPTSTYSERGTTITSMSVSTT 639

Query: 479 LKPDRKA---KPTPLDLRNN-TVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSI 534
           L    +A     TP+D     T   E    S   +  S    T+   S+    P+++  +
Sbjct: 640 LVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGST----PLTSMPV 695

Query: 535 TSTDSGDSEENYVPMQNPVSASPVPSGTN-SPAPKKSTGSVDYLALDFQPSSPSPHRKPS 593
            +T    SE + +      +++PV + T  S +P  + G+          S+PS    P 
Sbjct: 696 NTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA------SMPTSTPSEGSTPL 749

Query: 594 TSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPS 633
           TS   S   +   +     T  L  +    T    S  P+
Sbjct: 750 TSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPT 789



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 85/382 (22%), Positives = 142/382 (37%), Gaps = 66/382 (17%)

Query: 240  TKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHN 299
            T+ SL+ +  +   + T  +PS       G   + +M V  TP+ + ++    T   + N
Sbjct: 3375 TEASLSPTTAEGTSIPT-SSPSE------GTTPLASMPVSTTPVVSSEVNTLSTTPVDSN 3427

Query: 300  AM-TVATPGDSA--IAPPPRPPKPSQAE--TPRWGSPQQRPPISENSRSVAATIPRRNTL 354
             + T +T   S+  IA     P  + +E  TP    P    P++ +  S  +T P   + 
Sbjct: 3428 TLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTST 3487

Query: 355  PAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNY 414
            P   +S  +  SS  T E       +AG  +  +++         M V  +   +SE + 
Sbjct: 3488 PVTTSSPTN--SSPTTAEVTSMPTSTAGEGSTPLTN---------MPVSTTPVASSEAST 3536

Query: 415  VPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPV----HRGPSRGSEI 470
            +   P  S       +  +S    + ++       S G  S T  +    +   S  S  
Sbjct: 3537 LSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTP 3596

Query: 471  QPPPVNRNL----KPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYC 526
              P V+R+          + PTP +      +  LP  +P              S+    
Sbjct: 3597 STPSVDRSTPVTTSTQSNSTPTPPE------VITLPMSTPS-----------EVSTPLTI 3639

Query: 527  RPISTQSITSTDSGDSEENYVPMQNP------VSASPV-PSGTNSPAPKKSTGSVDYLAL 579
             P+ST S+T +++G +    V    P      VS+SPV P GT  P    S G       
Sbjct: 3640 MPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEG------- 3692

Query: 580  DFQPSSPSPHRKPSTSSVTSDE 601
                S+P      ST+ VTS E
Sbjct: 3693 ----STPLTTMPVSTTRVTSSE 3710



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 62/317 (19%), Positives = 108/317 (34%), Gaps = 36/317 (11%)

Query: 320  PSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGE 379
            PS+  TP    P    P++ +     +T P   + P   +++   +SS  T E       
Sbjct: 2805 PSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTK--ASSSPTTAEGIVVPIS 2862

Query: 380  SAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYI 439
            +A   +  ++    S  P       + ST   D  +P+   +    +   A   S  +  
Sbjct: 2863 TASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIST 2922

Query: 440  PMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVID 499
            P          +  P T++ V   P  GSE                  TP+D R      
Sbjct: 2923 P--------SEVSTPLTSILVSTVPVAGSEAS------------TLSTTPVDTRTPVTTS 2962

Query: 500  ELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVP 559
                 SP T   +       S+  +   P+++ S+++     SE + +      +++PV 
Sbjct: 2963 AEASSSPTT---AEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVT 3019

Query: 560  SGT---NSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQAL 616
            + T   +SP   + TG           S+PS    P TS   S   V   +     T  +
Sbjct: 3020 TSTEASSSPTTAEGTG--------IPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPV 3071

Query: 617  QNTMQEWTDVRQSSEPS 633
             +     T    SS P+
Sbjct: 3072 DSNSPVVTSTEVSSSPT 3088



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 71/351 (20%), Positives = 121/351 (34%), Gaps = 45/351 (12%)

Query: 280 ATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISE 339
           A+ LS   +  +  +  +  A + +T  +    P   P   S+  TP    P     +  
Sbjct: 528 ASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTP---SEGSTPLTNMPVSTRLVVS 584

Query: 340 NSRSVAATIPR-RNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPG 398
           +  S  +T P   NT     +     +++ E    P       G +  SMS         
Sbjct: 585 SEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVST------ 638

Query: 399 KMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTL 458
             +V  S+++      V  N   +T      +   ++   +P S     +     P T++
Sbjct: 639 -TLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTST----YTEGSTPLTSM 693

Query: 459 PVHR---GPSRGSEIQPPPVNRNLK-------------PDRKAKPTPLDLRNNTVIDELP 502
           PV+      S  S +   PV+ +                D  + PT      +T +  +P
Sbjct: 694 PVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP 753

Query: 503 F-KSPITKSWSRANHT--------FNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPV 553
             K+ +T S +    T          +S+   C P +T+  +   S  SE + +    PV
Sbjct: 754 VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPV 813

Query: 554 SASPVPS---GTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDE 601
           S +PV S    T S  P  S   V         SSP+P    S  + T  E
Sbjct: 814 SITPVTSPEASTLSTTPVDSNSPV--TTSTEVSSSPTPAEGTSMPTSTYSE 862



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 90/419 (21%), Positives = 143/419 (34%), Gaps = 71/419 (16%)

Query: 281  TPLSAYQIPRTFTLDKNHNAMTVAT-PGDS---------AIAPPPRPP-------KPSQA 323
            TPL++   P + TL  N  A T++T P DS         A +PPP           PS+ 
Sbjct: 983  TPLTS--TPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEG 1040

Query: 324  ETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASS--------CETYEYPQ 375
             TP    P     ++ +  S  +T P   + P    S+   +S+          TY    
Sbjct: 1041 STPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGS 1100

Query: 376  RGGESAGRSAESMSDGVGSFLPGKMI----------VGRSDSTNSEDNYVPMNPG----- 420
                S   S   +     S L    +             S  T +E   +P +P      
Sbjct: 1101 TPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTT 1160

Query: 421  -------SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPS----TTLPVHRGPSRGSE 469
                   S+TL+    A   S +     +  A   ++   P     T++P      R + 
Sbjct: 1161 PLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP 1220

Query: 470  IQPPPVNRNLKPDRKA---KPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYC 526
            +   PV        +A     +P+D             SP T   +    +  S  S   
Sbjct: 1221 LTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLL 1280

Query: 527  R--PISTQSITSTDSGD------SEENYVPMQNPVSASPVPS-GTNSPAPKKSTGSVDYL 577
               P+ST  +TS ++          +  V   N VS+SP P+ GT+ P    S G     
Sbjct: 1281 TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLT 1340

Query: 578  ALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQN-TMQEWTDVRQSSEPSKG 635
            ++    +  +     S  S+ S   VD        T+A  + T  E T +  +S PS+G
Sbjct: 1341 SIPVNTTLVA----SSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSM-PNSNPSEG 1394



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 85/418 (20%), Positives = 145/418 (34%), Gaps = 53/418 (12%)

Query: 244  LTGSETDNEDVYTFKTP--SNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAM 301
            L+ +  DN    T  T   S+    E   +   N     TPL++  +  T  +    + +
Sbjct: 1357 LSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTL 1416

Query: 302  TV-----ATPGDSAIAPPPRPPK----------PSQAETPRWGSPQQRPPISENSRSVAA 346
            +      +TPG ++      P            PS+ +TP    P    P++ +  S  +
Sbjct: 1417 SATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLS 1476

Query: 347  TIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSD 406
            T P  +  P + ++ +   SS  T         + G S    +   GS     + V  + 
Sbjct: 1477 TTPVDSNSPVVTSTAV---SSSPT--------PAEGTSIAISTPSEGSTALTSIPVSTTT 1525

Query: 407  STNSEDNYVPMNPG-SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPS 465
              +SE N +   P  +ST +       +S +     S     +     P T+LPV     
Sbjct: 1526 VASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLV 1585

Query: 466  RGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQY 525
              SE                  TP+D +           S   +  S    T +  S   
Sbjct: 1586 VSSEA------------NTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLL 1633

Query: 526  CR-PISTQSITSTDSGDSEENYVPMQNP------VSASPVPS-GTNSPAPKKSTGSVDYL 577
               P+ST  + S ++       V   +P      VS+SP P+ GT+ P    + G     
Sbjct: 1634 TSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLT 1693

Query: 578  ALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKG 635
            ++  + ++P      ST S T  +    V    E   +   T  E T +  +S PS+G
Sbjct: 1694 SITVR-TTPVASSAISTLSTTPVDNSTPVTTSTEARSS--PTTSEGTSM-PNSTPSEG 1747



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 80/410 (19%), Positives = 142/410 (34%), Gaps = 59/410 (14%)

Query: 269  GDLLVDNMDVPATPLSAYQIPRTFTLDKNHNA-MTVATPGDSA--IAPPPRPP--KPSQA 323
            G  L+ ++ V  TP+++ +     T   + +  +T +T G S+   A     P   PS+ 
Sbjct: 2867 GSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEV 2926

Query: 324  ETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGR 383
             TP         P++ +  S  +T P     P   ++    +SS  T E       + G 
Sbjct: 2927 STPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEA--SSSPTTAEGTSMPISTPGE 2984

Query: 384  SAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSP 443
                ++    S +P       + S    D   P+    +T      +   ++   IP+S 
Sbjct: 2985 RRTPLTSMSVSTMPVASSEASTLSRTPADTSTPV----TTSTEASSSPTTAEGTGIPIST 3040

Query: 444  GAHHFDSLGYPSTTLPVHRGP---SRGSEIQPPPVNRN----LKPDRKAKPTPLD----- 491
             +        P T++PV   P      S +   PV+ N       +  + PTP +     
Sbjct: 3041 PSEG----STPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMP 3096

Query: 492  ----LRNNTVIDELPFKS-PITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENY 546
                   +T +  +P  + P+T S   A  T +++      P++T +   +    SE   
Sbjct: 3097 ISTYSEGSTPLTGVPVSTTPVTSS---AISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTS 3153

Query: 547  VPMQNP------------------------VSASPVPSGTNSPAPKKSTGSVDYLALDFQ 582
            +P   P                        +SA+PV + T      ++T S         
Sbjct: 3154 MPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIP 3213

Query: 583  PSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEP 632
             S+PS    P TS   S+  V   +     T  + +     T    SS P
Sbjct: 3214 TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSP 3263



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 87/396 (21%), Positives = 138/396 (34%), Gaps = 63/396 (15%)

Query: 240  TKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQ--IPRTFTLDKN 297
            T    T S T         TPS       G   + ++ V  TP+++ +  I  T  +D N
Sbjct: 3197 TSTEATSSTTAEGTSIPTSTPSE------GMTPLTSVPVSNTPVASSEASILSTTPVDSN 3250

Query: 298  HNAMTVATPGDSAIAPPPRPP-------KPSQAETPRWGSPQQRPPISENSRSVAATIPR 350
                T  T    A + PP           PS+  TP    P     ++ +  S  +T P 
Sbjct: 3251 ----TPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA 3306

Query: 351  RNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNS 410
              + P    S+   +SS    +       +    +  +++   S  P       + ST  
Sbjct: 3307 DTSTPVTTYSQ--ASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP 3364

Query: 411  EDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEI 470
             D   P+   +   L+   A   S    IP S  +        P  ++PV   P   SE+
Sbjct: 3365 VDTSTPVTTSTEASLSPTTAEGTS----IPTSSPSEGTT----PLASMPVSTTPVVSSEV 3416

Query: 471  ---QPPPVNRNLK-------------PDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRA 514
                  PV+ N                +  + PT      +T +  +P  +  T   S  
Sbjct: 3417 NTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLST--TPVASSE 3474

Query: 515  NHTFNSSSSQYCRPISTQS----------ITSTDSGDSEENYVPMQN-PVSASPVPSGTN 563
              T +++      P++T S          +TS  +  + E   P+ N PVS +PV S   
Sbjct: 3475 ASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVAS--- 3531

Query: 564  SPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTS 599
            S A   ST  VD  +  F  SS      P+T  VT+
Sbjct: 3532 SEASTLSTTPVD--SNTFVTSSSQASSSPATLQVTT 3565



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 67/356 (18%), Positives = 115/356 (32%), Gaps = 35/356 (9%)

Query: 280  ATPLSAYQIPRTFTLDKNHNAMT---------VATPGDSAIAPPPRPPKPSQAETPRWGS 330
            +TPL++  + +T       + ++         + T  +++ +P           TP  GS
Sbjct: 746  STPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGS 805

Query: 331  PQQRP-PISENSRSVAATIPRRNTL---PAMDNSRLHRASSCETYEYPQRGGESAGRSAE 386
            P     P+S        T P  +TL   P   NS +  ++   +   P  G      +  
Sbjct: 806  PLLTSIPVS----ITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYS 861

Query: 387  SMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMS-PGA 445
                 + S      +V  S  +      V  +   +       +   S+   +P S PG 
Sbjct: 862  EGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGE 921

Query: 446  HHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKS 505
                    P +T PV    +R     P   +  +    +A  +P      ++    P + 
Sbjct: 922  GSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEG 981

Query: 506  PITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSAS---PVPSGT 562
                + +  +HT  ++S       ST S T  DS        P+     AS   P   GT
Sbjct: 982  TTPLTSTPVSHTLVANSE-----ASTLSTTPVDSN------TPLTTSTEASSPPPTAEGT 1030

Query: 563  NSPAPKKSTGSVDYLALDFQP---SSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQA 615
            + P    S GS     +       +S       +T + TS     Y Q     T A
Sbjct: 1031 SMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTA 1086



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 76/385 (19%), Positives = 144/385 (37%), Gaps = 37/385 (9%)

Query: 240  TKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFT--LDKN 297
            T    + S T  ED+     P +T     G  L+ ++ V  TP+++ +     T  +D N
Sbjct: 2489 TSTEASSSPTTAEDIVV---PISTASE--GSTLLTSIPVSTTPVASPEASTLSTTPVDSN 2543

Query: 298  HNAMT---VATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTL 354
               +T   +++   SA          S+  TP    P    P++ +  S  +T P   ++
Sbjct: 2544 SPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI 2603

Query: 355  PAMDNSRLHRASSCETYEYPQRGGESAG--RSAESMSDGVGSFLPGKMIVGRSDSTNSED 412
            P          +S ET   P    +++    +   +S  + S L   M V  S+++    
Sbjct: 2604 PV--------TTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLST 2655

Query: 413  NYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLG--YPSTTLPVHRGPSRGSEI 470
              V      +T      +   ++   +P S        L     STTL  +   S  S +
Sbjct: 2656 TPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLAN---SEASTL 2712

Query: 471  QPPPVNRN----LKPDRKAKPTPLD---LRNNTVID-ELPFKSPITKSWSRAN---HTFN 519
               PV+ +       +  + PT  +   +R +T  D   P  S +  +   A+    T +
Sbjct: 2713 STTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVS 2772

Query: 520  SSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSAS-PVPSGTNSPAPKKSTGSVDYLA 578
            +++     P++T +  S+    +E   +P   P   S P+ S   +  P  S+ +     
Sbjct: 2773 TTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLST 2832

Query: 579  LDFQPSSPSPHRKPSTSSVTSDEKV 603
                 S+P      ++SS T+ E +
Sbjct: 2833 TPVDTSTPVTTSTKASSSPTTAEGI 2857


>gi|50234893 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 1 [Homo
           sapiens]
          Length = 404

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 24/77 (31%), Positives = 45/77 (58%), Gaps = 14/77 (18%)

Query: 4   DPDVLEYYKNDHSKKPLRIINLNF------CEQVDAGLTFNKKELQDSFVFDIKTSERTF 57
           D + + Y+K++  K+PLR+I L        C+Q D  +  N        +F+I T+ RTF
Sbjct: 216 DENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDN--------LFEIVTTSRTF 267

Query: 58  YLVAETEEDMNKWVQSI 74
           Y+ A++ E+M+ W++++
Sbjct: 268 YVQADSPEEMHSWIKAV 284


>gi|31377720 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 1 [Homo
           sapiens]
          Length = 404

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 24/77 (31%), Positives = 45/77 (58%), Gaps = 14/77 (18%)

Query: 4   DPDVLEYYKNDHSKKPLRIINLNF------CEQVDAGLTFNKKELQDSFVFDIKTSERTF 57
           D + + Y+K++  K+PLR+I L        C+Q D  +  N        +F+I T+ RTF
Sbjct: 216 DENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDN--------LFEIVTTSRTF 267

Query: 58  YLVAETEEDMNKWVQSI 74
           Y+ A++ E+M+ W++++
Sbjct: 268 YVQADSPEEMHSWIKAV 284


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/222 (22%), Positives = 90/222 (40%), Gaps = 24/222 (10%)

Query: 211 YSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKT-------PSNT 263
           +S PK ++ +   +D+  +  ++   H  TK        D+E   + K         S  
Sbjct: 169 FSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKD 228

Query: 264 LCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPK---- 319
             R+ G+  +   +    P +A++ P+   +      +   +P      PPP PP+    
Sbjct: 229 TSRKLGEGRLPKEEKAPPPKAAFKEPK---MALKETKLESTSPKGGPPPPPPPPPRASSK 285

Query: 320 -PSQAETPRWGSPQQRPPISENSRSVAATIPRRNT-------LPAMDNSRLHRASSCETY 371
            P+ A++P+  + +Q+   S+ SRS   T PR ++        PA D S   R    +  
Sbjct: 286 RPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSST-RGEKVKAE 344

Query: 372 EYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDN 413
             P R  + A    ES S+   SF         S+S++S D+
Sbjct: 345 SEP-REAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDS 385


>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
          Length = 904

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 97/425 (22%), Positives = 143/425 (33%), Gaps = 51/425 (12%)

Query: 103 SPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAP-QEYLYLHQCI 161
           +PA  S++S H+    + S    +  PT     P V+N      S++AP       H  +
Sbjct: 305 NPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAASHPAV 364

Query: 162 SRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSR--- 218
              A + R A+  QG  A  +    T +   +          +  V      P  SR   
Sbjct: 365 PPSAPDPRPAT-PQGGGAPRVAAPQTTLSSSSTS--------AATVDPPAWTPSASRTQQ 415

Query: 219 -HNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMD 277
             N  F+ S      SL+  G T   +   ++  E    F   + +   E G        
Sbjct: 416 ARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAG-APAPGRP 474

Query: 278 VPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPI 337
            PAT       P+T              P  S +A P +   P     P    P    P+
Sbjct: 475 SPATAAVPSSQPKT------------EAPQASPLAKPLQSSSPRVLGLPSRMEPP--APL 520

Query: 338 SENSRSVAATIP---RRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRS-------AES 387
           S +S S A+ +P   RRN   +    R+  A S    E P   G+S   +        E 
Sbjct: 521 STSSTSQASALPPAGRRNLAESSGVGRV-GAGSRPKPEAPMAKGKSTTLTQDMSTSLQEG 579

Query: 388 MSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHH 447
             DG   +      V R            + P     LA  RAG+  + V    +   H 
Sbjct: 580 QEDGPAGWRANLKPVDRRSPAER-----TLKPKEPRALAEPRAGEAPRKVSGSFAGSVHI 634

Query: 448 FDSLGYPS-TTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSP 506
             +   P  T  P   GPS  +    PP  R L     A P  LD+ +N +  E P +  
Sbjct: 635 TLTPVRPDRTPRPASPGPSLPARSPSPPRRRRL-----AVPASLDVCDNWLRPEPPGQEA 689

Query: 507 ITKSW 511
             +SW
Sbjct: 690 RVQSW 694


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 108/487 (22%), Positives = 170/487 (34%), Gaps = 84/487 (17%)

Query: 165 AENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFR 224
           +E AR+A   +  R   ++   T     +Q  G  VN   G      S P  S   T F 
Sbjct: 135 SEQARAAGAREKERQETVINHST-FSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFS 193

Query: 225 D---STYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPAT 281
           D   S   +  S A+  H   S T S    E   +   P  T                 T
Sbjct: 194 DYGVSVTFITGSTATK-HFLDSSTNSGHSEESTVSHSGPGAT---------------GTT 237

Query: 282 PLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENS 341
              ++     F  +   + +T A+   +A+         S+  T  + SP+        +
Sbjct: 238 LFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPA 297

Query: 342 RSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMI 401
           R+ ++ +  ++T         H  +  ++   P       G S ES +           I
Sbjct: 298 RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMP-------GVSQESTAS--------HSI 342

Query: 402 VGRSDSTNSEDNYVP--MNPGSSTLLAME------RAGDNSQ-SVYIPMSPGAHHFDSLG 452
            G +D+T S     P  + P S+T  +        R  DN+  S  +  S   H   S G
Sbjct: 343 PGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVH--SSTG 400

Query: 453 YPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWS 512
            P TTL     PS  +  +  P      P  K              D  P  S  T ++ 
Sbjct: 401 SPHTTL----SPSSSTTHEGEPTTFQSWPSSK--------------DTSPAPSGTTSAFV 442

Query: 513 RANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKST- 571
           + + T++SS S    P +  S +ST  G SEE+      PV +SPV + T  P  + +T 
Sbjct: 443 KLSTTYHSSPSS--TPTTHFSASSTTLGHSEES-----TPVHSSPVATATTPPPARSATS 495

Query: 572 GSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSE 631
           G V+         S + HR P ++      +        E++     +    T   +SS 
Sbjct: 496 GHVE--------ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGS----TTHTKSST 543

Query: 632 PSKGAKL 638
           PS  A L
Sbjct: 544 PSTTAAL 550



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 134/570 (23%), Positives = 201/570 (35%), Gaps = 104/570 (18%)

Query: 93   VSSAGHG-PRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHM-----QPTL 146
            VS+  H  P S+P    S+S   L   + S   HSS     T   P  +       +PT 
Sbjct: 4246 VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 4305

Query: 147  S--TSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGIS 204
            S  +S   E   L    +    + +S +F    R+      DT +   +  +    +G+S
Sbjct: 4306 SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTS----SGVS 4356

Query: 205  GQVHGFYSLPKPSRHNTEFRDSTYDLP----RSLASHGH--------TKGSLTGSETDNE 252
             +    +S P  S H T F  ST  +P     S ASH          + GS T S    E
Sbjct: 4357 EESTTSHSRPG-SMHTTAFPSST-TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE 4414

Query: 253  DVYTFKTPSNTLCREFGD------LLVDNMDVPATPLSAYQI--PRTFTLDKNHNAMTVA 304
                  +P +T      D      LL  +  V ++  S +    P   T  +  +    +
Sbjct: 4415 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 4474

Query: 305  TPG--DSAIAPPPRPPKPSQAETPRWGSPQQRPPI-----------SENSRSV------A 345
             P   D+  APP       +  T   GSP   P             SE S +V       
Sbjct: 4475 WPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 4534

Query: 346  ATIP---RRNTLPAMDNSRLHRAS--SCETYEYPQRGGESAGRSAESMSDGVGSFLPGKM 400
            AT P   R  T   ++ S  + +S  S +T  +P+    ++GR  ES +           
Sbjct: 4535 ATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE-SNTTSGRGEESTT----------- 4582

Query: 401  IVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPV 460
                  S +S  + +   P +++ L  E    +S     P S    HF      S+T   
Sbjct: 4583 ------SHSSTTHTISSAPSTTSALVEEPTSYHSS----PGSTATTHFPD----SSTTSG 4628

Query: 461  HRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFK------SPITKSWSRA 514
                S  S          + P R      L     + I     +      S  T   S  
Sbjct: 4629 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK 4688

Query: 515  NHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSV 574
            + TF+SS S    P +  S +ST  G SEE+     +PV+ +  P    SPA   ++G V
Sbjct: 4689 STTFHSSPSS--TPTTHFSASSTTLGRSEESTTVHSSPVATATTP----SPARSTTSGLV 4742

Query: 575  -DYLALDFQPSSPSPHRKP--STSSVTSDE 601
             +  A    P S      P  ST+S  S+E
Sbjct: 4743 EESTAYHSSPGSTQTMHFPESSTASGRSEE 4772



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 127/551 (23%), Positives = 194/551 (35%), Gaps = 78/551 (14%)

Query: 86   STDSLRNVSSAGH-GPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQP 144
            +T SL   S+  +  PRS  A LS ++       + S+ SHS   +  T   P S     
Sbjct: 1432 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS----- 1486

Query: 145  TLSTSAPQEYLYLHQCISRRAENARSASFSQG-TRASFLMRSDTAVQKLAQGNGHCVNGI 203
            T ++   QE    H      ++ +  A+ S G T AS L +  T            +   
Sbjct: 1487 TTTSDLSQEPTTSHS-----SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 1541

Query: 204  SGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNT 263
                 G      P+  +T    +T   P S  S G  + S T     +    T  +P  T
Sbjct: 1542 DTITSGLVEASTPTHSSTGSLHTTLT-PASSTSAGLQEESTTFQSWPSSSDTT-PSPPGT 1599

Query: 264  LCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTV-ATPGDSAIAPPPRPPKPSQ 322
                       +    +TP + +    T TL ++  + TV ++PG +  A  P       
Sbjct: 1600 TAAPVEVSTTYHSRPSSTPTTHFSASST-TLGRSEESTTVHSSPGATGTALFPT----RS 1654

Query: 323  AETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAG 382
            A +   G P   P  S ++ + A        LP    +      S   Y  P R  ++  
Sbjct: 1655 ATSVLVGEPTTSPISSGSTETTA--------LPGSTTTAGLSEKSTTFYSSP-RSPDTTL 1705

Query: 383  RSAESMSDGVGSFLPGKMIVGRSDSTNSEDN----YVPMNPGSSTL--LAMERAGDNSQ- 435
              A + S GV             +ST S       +    PGS+T+  ++ E    +S  
Sbjct: 1706 SPASTTSSGVSE-----------ESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1754

Query: 436  -SVYIPMSPGAHHFDSLGYPSTT------------LPVHRGPSRGSEIQPPPVNRNLKPD 482
             S    +SPG+    SLG  STT            LP +   S   E   P  +    P 
Sbjct: 1755 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPH 1814

Query: 483  RKAKPTPLDLRNNTVI---------DELPFKSPITKSWSRANHTFNSSSSQYCRPISTQS 533
                P     R              D +P     T ++   + T + S S    P +  S
Sbjct: 1815 TTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSS--TPTTHFS 1872

Query: 534  ITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSV-DYLALDFQPSSPSPHRKP 592
             +ST  G SEE+     +PV+ +  P    SPA   ++G V +  A    P S      P
Sbjct: 1873 ASSTTLGRSEESTTVHSSPVATATTP----SPARSTTSGLVEESTAYHSSPGSTQTMHFP 1928

Query: 593  --STSSVTSDE 601
              ST+S  S+E
Sbjct: 1929 ESSTASGRSEE 1939



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 124/523 (23%), Positives = 188/523 (35%), Gaps = 83/523 (15%)

Query: 86   STDSLRNVSSAGH-GPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQP 144
            +T SL   S+  +  PRS  A LS ++       + S+ SHS   +  T   P S     
Sbjct: 2989 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS----- 3043

Query: 145  TLSTSAPQEYLYLHQCISRRAENARSASFSQG-TRASFLMRSDTAVQKLAQGNGHCVNGI 203
            T ++   QE    H      ++ +  A+ S G T AS L +  T            +   
Sbjct: 3044 TTTSGLSQEPTASHS-----SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 3098

Query: 204  SGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNT 263
                 G      P+  +T    +T   P S  S G  + S T     +    T  +P  T
Sbjct: 3099 DTITSGLVEASTPTHSSTGSLHTTLT-PASSTSAGLQEESTTFQSWPSSSDTT-PSPPGT 3156

Query: 264  LCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTV-ATPGDSAIAPPPRPPKPSQ 322
                       +    +TP + +    T TL ++  + TV ++PG +  A  P       
Sbjct: 3157 TAAPVEVSTTYHSRPSSTPTTHFSASST-TLGRSEESTTVHSSPGATGTALFPT----RS 3211

Query: 323  AETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAG 382
            A +   G P   P  S ++ + A        LP    +      S   Y  P R  ++  
Sbjct: 3212 ATSVLVGEPTTSPISSGSTETTA--------LPGSTTTAGLSEKSTTFYSSP-RSPDTTL 3262

Query: 383  RSAESMSDGVGSFLPGKMIVGRSDSTNSEDN----YVPMNPGSSTL--LAMERAGDNSQ- 435
              A + S GV             +ST S       +    PGS+T+  ++ E    +S  
Sbjct: 3263 SPASTTSSGVSE-----------ESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 3311

Query: 436  -SVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGS--------------EIQPPPVNRNLK 480
             S    +SPG+    SLG  STT   H GP                  E   P  +    
Sbjct: 3312 GSTDTTLSPGSTTASSLGPESTTF--HSGPGSTETTLLPDNTTASGLLEASTPVHSSTGS 3369

Query: 481  PDRKAKPTPLDLRNNTVIDELPFKS-PITKSWSRANHTFNS-----SSSQYCRPISTQ-- 532
            P     P     R     +   F+S P +K  + A  T  S     S++ +  P ST   
Sbjct: 3370 PHTTLSPAGSTTRQG---ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 3426

Query: 533  --SITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGS 573
              S +ST  G SEE+       V +SPV + T +P+P +ST S
Sbjct: 3427 HFSASSTTLGRSEES-----TTVHSSPVATAT-TPSPARSTTS 3463



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 125/521 (23%), Positives = 189/521 (36%), Gaps = 79/521 (15%)

Query: 86   STDSLRNVSSAGH-GPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQP 144
            +T SL   S+  +  PRS  A LS ++       + S+ SHS   +  T   P S     
Sbjct: 4072 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS----- 4126

Query: 145  TLSTSAPQEYLYLHQCISRRAENARSASFSQG-TRASFLMRSDTAVQKLAQGNGHCVNGI 203
            T ++   QE    H      ++ +  A+ S G T AS L +  T            +   
Sbjct: 4127 TTTSGLSQEPTTSHS-----SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 4181

Query: 204  SGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNT 263
                 G      P+  +T    +T   P S  S G  + S T     +    T   PS T
Sbjct: 4182 DTITSGLVEASTPTHSSTGSLHTTLT-PASSTSTGLQEESTTFQSWPSSSDTTPSPPSTT 4240

Query: 264  LCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTV-ATPGDSAIAPPPRPPKPSQ 322
                       +    +TP + +    T TL ++  + TV ++PG +  A  P       
Sbjct: 4241 AVPVEVSTTYHSRP-SSTPTTHFSASST-TLGRSEESTTVHSSPGATGTALFPT----RS 4294

Query: 323  AETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAG 382
            A +   G P   P  S ++ + A        LP    +      S   Y  P R  ++  
Sbjct: 4295 ATSVLVGEPTTSPISSGSTETTA--------LPGSTTTAGLSEKSTTFYSSP-RSPDTTL 4345

Query: 383  RSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMN----PGSSTL--LAMERAGDNSQ- 435
              A + S GV             +ST S      M+    P S+T+  ++ E    +S  
Sbjct: 4346 SPASTTSSGVSE-----------ESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP 4394

Query: 436  -SVYIPMSPGAHHFDSLGYPSTT------------LPVHRGPSRGSEIQPPPVNRNLKPD 482
             S    +SPG+    SLG  STT            LP +   S   E   P  +    P 
Sbjct: 4395 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPH 4454

Query: 483  RKAKPTPLDLRNNTVIDELPFKS-PITKSWSRANHTFNS-----SSSQYCRPISTQ---- 532
                P     R     +   F+S P +K  + A  T  S     S++ +  P ST     
Sbjct: 4455 TTLSPAGSTTRQG---ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHF 4511

Query: 533  SITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGS 573
            S +ST  G SEE+       V +SPV + T +P+P +ST S
Sbjct: 4512 SASSTTLGRSEES-----TTVHSSPVATAT-TPSPARSTTS 4546



 Score = 36.6 bits (83), Expect = 0.073
 Identities = 115/551 (20%), Positives = 183/551 (33%), Gaps = 84/551 (15%)

Query: 92  NVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSN-HMQPTLSTSA 150
           N +++G    S+P   S+ S H      SS+ +H  +PT F   P   +    P+ +TSA
Sbjct: 382 NTTTSGLLEASTPVHSSTGSPHTTLS-PSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA 440

Query: 151 PQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQK----LAQGNGHCVNGISGQ 206
              ++ L         +  +  FS  +         T V       A       +  SG 
Sbjct: 441 ---FVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGH 497

Query: 207 VHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLT--GSETDNEDVYTFKTPSNTL 264
           V         + H +     T   P S  + GH++ S T  GS T  +      TPS T 
Sbjct: 498 VE-----ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS----STPSTTA 548

Query: 265 CREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQA- 323
                     +  + +T  + ++   T +     +  + ++P   A    P    PS   
Sbjct: 549 ALAHTSY---HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLV 605

Query: 324 --ETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESA 381
              TP         PIS  S    A +P   T P +       +    T+    R  ++ 
Sbjct: 606 GDSTP--------SPISSGSMETTA-LPGSTTKPGL-------SEKSTTFYSSPRSPDTT 649

Query: 382 GRSAESMSDGVGSFLPGKMIVGRSDSTNSE----DNYVPMNPGSSTLLAMERAGDNSQSV 437
              A   S GV             +ST S       +    PGS+T+  + +    S S 
Sbjct: 650 HLPASMTSSGVS-----------EESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 698

Query: 438 YIP----MSPGAHHFDSLGYPSTT------------LPVHRGPSRGSEIQPPPVNRNLKP 481
             P    +SPG+    SLG   TT            LP +   S   E   P  +    P
Sbjct: 699 PGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP 758

Query: 482 DRKAKPTPLDLR--NNTVIDELPFK-----SPITKSWSRANHTFNSSSSQYCRPISTQSI 534
                P     R   +T     P       +P T + +    +  S  S    P +  S 
Sbjct: 759 HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 818

Query: 535 TSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPST 594
            ST SG  EE+     +P S   +    + P    ++G  +        ++ +    PST
Sbjct: 819 RSTTSGLVEESTTYHSSPGSTQTM----HFPESDTTSGRGEESTTSHSSTTHTISSAPST 874

Query: 595 SSVTSDEKVDY 605
           +S   +E   Y
Sbjct: 875 TSALVEEPTSY 885


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 85/388 (21%), Positives = 135/388 (34%), Gaps = 89/388 (22%)

Query: 313 PPPRPPKPS--QAETPRWGSPQQRPPISENSRSV----AATIPRRNTLPAMDNSRLHRAS 366
           P PR P+P   QAE P+  +    P +            +  P++    ++  SR  R  
Sbjct: 483 PKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRR 542

Query: 367 SCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLA 426
                   +    SA  S  S S    S   G    G S S +   +Y   +  SS   +
Sbjct: 543 --------KTSASSASASNSSRSSSRSSSYSGS---GSSRSRSRSSSYSSYSSRSSRHSS 591

Query: 427 MERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGS-EIQPPPVNRNLKPDRKA 485
              +   S+S           F S   PS T   HR   R   E  PPP     K  +K 
Sbjct: 592 FSGSRSRSRS-----------FSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKP 640

Query: 486 KPTPLDLRNNTVI-----------------DELPFKSP-----ITKSWSRANHTFNSSSS 523
            P P   +                       E P ++P     ++ S S +  +++ SSS
Sbjct: 641 APPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSS 700

Query: 524 QYCRPISTQSITSTDSG----------DSEENYVPMQNPVSA----SPVPSGT------- 562
           +  R +S  S++S  S           DSE+ Y  + +PVS+    SP P+ T       
Sbjct: 701 R-SRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKS 759

Query: 563 --------------NSPAPKKSTGSVDYLALDFQPSSP--SPHRKPSTSSVTSDEKVDYV 606
                         +S  P KS           QPS+P  +P  +P   +  + +++   
Sbjct: 760 KKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLT 819

Query: 607 QVDKEKTQALQNTMQEWTDVRQSSEPSK 634
            ++K   +  +   +     RQS  P+K
Sbjct: 820 LLNKAADKGSRKRYEPSDKDRQSPPPAK 847


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 56/226 (24%), Positives = 84/226 (37%), Gaps = 29/226 (12%)

Query: 380  SAGRSAESMSDGVGSFLPG-----KMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNS 434
            +AG S  + SD  G F PG         G   S      Y+P +PG     AM  +   +
Sbjct: 1543 AAGFSPSAASDASG-FSPGYSPAWSPTPGSPGSPGPSSPYIP-SPGG----AMSPSYSPT 1596

Query: 435  QSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKA-KPTPLDLR 493
               Y P SPG +   S  Y S T P +   S        P + N  P   +  PT     
Sbjct: 1597 SPAYEPRSPGGYTPQSPSY-SPTSPSYSPTSPSYS----PTSPNYSPTSPSYSPTS---- 1647

Query: 494  NNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPV 553
                    P  SP + S+S  + +++ +S  Y     + S TS     +  +Y P     
Sbjct: 1648 --------PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1699

Query: 554  SASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTS 599
            S +       SP+   ++ S    +  + P+SPS      + S TS
Sbjct: 1700 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1745



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 50/224 (22%), Positives = 78/224 (34%), Gaps = 20/224 (8%)

Query: 391  GVGSFLPGKMIVGRSDSTNS--EDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHF 448
            G+G+  P  M  G + S          P N G++        G  S SV   M+PGA  F
Sbjct: 1492 GLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAY-----GAWSPSVGSGMTPGAAGF 1546

Query: 449  D----------SLGYPSTTLPVHRGPSRGSEIQP--PPVNRNLKPDRKAKPTPLDLRN-N 495
                       S GY     P    P       P  P     + P         + R+  
Sbjct: 1547 SPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPG 1606

Query: 496  TVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSA 555
                + P  SP + S+S  + +++ +S  Y     + S TS     +  +Y P     S 
Sbjct: 1607 GYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1666

Query: 556  SPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTS 599
            +       SP+   ++ S    +  + P+SPS      + S TS
Sbjct: 1667 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1710



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 502  PFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQ---NPVSASPV 558
            P  SP + S+S  + +++ +S  Y     + S TS +   +  NY P     +P S S  
Sbjct: 1711 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYS 1770

Query: 559  PSGTN--SPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVT 598
            P+  N    +P  S  S  Y       S  SP   PS+   T
Sbjct: 1771 PTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYT 1812



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 73/303 (24%), Positives = 103/303 (33%), Gaps = 36/303 (11%)

Query: 302  TVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRN-TLPAMDNS 360
            T  +P  S  +P   P  PS + T    SP   P  S  S S + T P  + T P+   +
Sbjct: 1609 TPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSPT 1667

Query: 361  RLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG 420
                + +  +Y            S    S       P       S S  S  +Y P +P 
Sbjct: 1668 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPS 1726

Query: 421  SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPP---PVNR 477
             S           +   Y P SP ++   S  Y S T P +   S       P   P + 
Sbjct: 1727 YSP----------TSPSYSPTSP-SYSPTSPNY-SPTSPNYTPTSPSYSPTSPSYSPTSP 1774

Query: 478  NLKPDR-KAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITS 536
            N  P      PT             P  SP + S+S  + +++ SS +Y     T + +S
Sbjct: 1775 NYTPTSPNYSPTS------------PSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSS 1822

Query: 537  TDSGDSEENYVPMQ---NPVSASPVPSGT--NSPAPKKSTGSVDYLALDFQPSSPSPHRK 591
                 S  +Y P      P S S  PS       +PK S  S  Y     + S  SP   
Sbjct: 1823 PSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYS 1882

Query: 592  PST 594
            P+T
Sbjct: 1883 PTT 1885



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 7/105 (6%)

Query: 502  PFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQ---NPVSASPV 558
            P  SP + S+S  +  ++ +S  Y     + S TS     +  NY P     +P S S  
Sbjct: 1732 PSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYS 1791

Query: 559  PSGTN-SP-APKKSTGSVDYLALD--FQPSSPSPHRKPSTSSVTS 599
            P+  + SP +P  S  S  Y      + PSSPS      + S TS
Sbjct: 1792 PTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTS 1836



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 502  PFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQ-NPVSASPVPS 560
            P  SP + S+S  + +++ +S  Y     + S TS     +  NY P   N    SP  S
Sbjct: 1704 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYS 1763

Query: 561  GTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTS 599
             T SP+   ++ +    + ++ P+SPS      + S TS
Sbjct: 1764 PT-SPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTS 1801



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 75/323 (23%), Positives = 109/323 (33%), Gaps = 33/323 (10%)

Query: 281  TPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISEN 340
            +P S    P + +      + +  +P  S  +P   P  PS + T    SP   P  S  
Sbjct: 1665 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPT 1723

Query: 341  SRSVAATIPRRN-TLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGK 399
            S S + T P  + T P+   +  + + +   Y            S    S       P  
Sbjct: 1724 SPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNY 1783

Query: 400  MIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTT-- 457
                 S S  S  +Y P +P  S   +  R    S + Y P SP ++   S  Y  T+  
Sbjct: 1784 SPTSPSYSPTSP-SYSPTSPSYSP--SSPRYTPQSPT-YTPSSP-SYSPSSPSYSPTSPK 1838

Query: 458  -LPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANH 516
              P     S  S    P   +      K  PT       +     P  SP T  +S  + 
Sbjct: 1839 YTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTS-----PTYSPTTPKYSPTSP 1893

Query: 517  TFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDY 576
            T++ +S  Y       S TS     +   Y P       SP  S T   +PK ST     
Sbjct: 1894 TYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSP------TSPTYSPT---SPKGST----- 1939

Query: 577  LALDFQPSSPSPHRKPSTSSVTS 599
                + P+SP       T S+TS
Sbjct: 1940 ----YSPTSPGYSPTSPTYSLTS 1958



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 64/320 (20%), Positives = 109/320 (34%), Gaps = 21/320 (6%)

Query: 281  TPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISEN 340
            TP S    P + +      + +  +P  S  +P   P  PS + T    SP   P  S  
Sbjct: 1609 TPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPT 1667

Query: 341  SRSVAATIPRRN-TLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGK 399
            S S + T P  + T P+   +    + +  +Y            S    S       P  
Sbjct: 1668 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1727

Query: 400  MIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLP 459
                 S S  S  +Y P +P  S           +   Y P SP ++   S  Y S T P
Sbjct: 1728 SPTSPSYSPTSP-SYSPTSPNYSP----------TSPNYTPTSP-SYSPTSPSY-SPTSP 1774

Query: 460  VHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFN 519
             +  P+  +     P      P            +     + P  +P + S+S ++ +++
Sbjct: 1775 NYT-PTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYS 1833

Query: 520  SSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLAL 579
             +S +Y     + S +S +   +   Y P     S +       SP    +T      + 
Sbjct: 1834 PTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSP 1893

Query: 580  DFQPSSP-----SPHRKPST 594
             + P+SP     SP   P++
Sbjct: 1894 TYSPTSPVYTPTSPKYSPTS 1913



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 68/327 (20%), Positives = 106/327 (32%), Gaps = 11/327 (3%)

Query: 281  TPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISEN 340
            +P S    P +        + +  +P  S  +P   P  PS + T    SP   P  S  
Sbjct: 1623 SPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPT 1681

Query: 341  SRSVAATIPRRN-TLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGK 399
            S S + T P  + T P+   +    + +  +Y            S    S       P  
Sbjct: 1682 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1741

Query: 400  MIVGRSDSTNSEDNYVPMNPG-SSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTL 458
                 + S  S  NY P +P  S T  +      N    Y P SP  +   S  Y S T 
Sbjct: 1742 SPTSPNYSPTSP-NYTPTSPSYSPTSPSYSPTSPN----YTPTSPN-YSPTSPSY-SPTS 1794

Query: 459  PVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTF 518
            P +  P+  S     P      P            + +     P  +P + S+S ++  +
Sbjct: 1795 PSY-SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEY 1853

Query: 519  NSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLA 578
              +S +Y       S TS     +   Y P     S +       SP    ++      +
Sbjct: 1854 TPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTS 1913

Query: 579  LDFQPSSPSPHRKPSTSSVTSDEKVDY 605
              + P+SP       T S TS +   Y
Sbjct: 1914 PTYSPTSPKYSPTSPTYSPTSPKGSTY 1940


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 122/570 (21%), Positives = 182/570 (31%), Gaps = 98/570 (17%)

Query: 93   VSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQ 152
            +SS G  P S+    S +   LL      A   SS+PT  + EPP     +PT + + PQ
Sbjct: 1233 LSSTGPSPSSNHTPASPTQTPLL-----PATLTSSKPTASSGEPP-----RPTTAVT-PQ 1281

Query: 153  EYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYS 212
                L    + R+  A   + +Q T  +    +  A    AQ                 +
Sbjct: 1282 ATSGLPPTATLRS-TATKPTVTQATTRATASTASPATTSTAQSTTRTT----------MT 1330

Query: 213  LPKPSRHNTEF---RDSTYDLPRSLASHGH----TKGSLTGSETDNEDVYTFKTPSNTLC 265
            LP P+   T     + +  +LP + A+       T  S TG  T      T  T + T  
Sbjct: 1331 LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQ 1390

Query: 266  REFGDLLVDNMDVPATPLSAYQIPRT---------FTLDKNHNAMTVATPGDSAIAPPPR 316
                         P TP + +  P            T    H   T  TP       P  
Sbjct: 1391 TR----TTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTH 1446

Query: 317  -PPKPSQAETPRWGSP-----QQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCET 370
             PP  +   TP   +       Q    + N  +   TIP   TL A  ++  H A     
Sbjct: 1447 VPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGST--HTAPPIT- 1503

Query: 371  YEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERA 430
               P   G S   S+ S +    S           + T +    +  NP +ST      A
Sbjct: 1504 ---PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP-TSTRTRTPVA 1559

Query: 431  GDNSQSVYIPMSP--------GAHHFDSLG-----------------YPSTTLPVHRGPS 465
              NS +   P  P        G+  F S G                 +P TTLP H  P 
Sbjct: 1560 HTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPF 1619

Query: 466  RGSEIQP------PPVNRNLKPDRKAK-------PTPLDLRNNTVIDELPFKSPITKSWS 512
              S + P       P +  +              P P  L+        P  +  T   S
Sbjct: 1620 STSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTS 1679

Query: 513  RANHTFN---SSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKK 569
            +A  + N   +S+S +    ST    +T +  S  N  P        P+   T+  +  +
Sbjct: 1680 QALSSLNTAKTSTSLHSHTSSTHHAEATST--STTNITPNPTSTGTPPMTVTTSGTSQSR 1737

Query: 570  STGSVDYLALDFQPSSPSPHRKPSTSSVTS 599
            S+ S    +      + S H    TS+ T+
Sbjct: 1738 SSFSTAKTSTSLHSHTSSTHHPEVTSTSTT 1767



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 37/182 (20%), Positives = 63/182 (34%), Gaps = 29/182 (15%)

Query: 453  YPSTTLPVHRGPSRGSEIQPPP----VNRNLKPDRKAK---------PTPLDLRNNTVID 499
            +P TTLP H  P   S + P      +  + +    A          P P  L+      
Sbjct: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTH 2059

Query: 500  ELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQ--------N 551
              P  +  T   S+ + +F+++++      S+  +    S     + +  Q         
Sbjct: 2060 TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT 2119

Query: 552  PVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKE 611
            PVS +   S + SP+P   +    Y+        PS H  P TSS +      +V     
Sbjct: 2120 PVSTTNQLSSSFSPSPSAPSTVSSYV--------PSSHSSPQTSSPSVGTSSSFVSAPVH 2171

Query: 612  KT 613
             T
Sbjct: 2172 ST 2173


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 127/549 (23%), Positives = 195/549 (35%), Gaps = 113/549 (20%)

Query: 94   SSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQP--TLSTSAP 151
            +++G G  S+ +   SS+ H +    SSAPS +S       E P S H  P  T +T  P
Sbjct: 770  TTSGRGEESTTSH--SSTTHTI----SSAPSTTSA----LVEEPTSYHSSPGSTATTHFP 819

Query: 152  QEYLYLHQCISRRAENARSASFSQGTRASFLM--RSDTAVQKLAQGNGHCVNGISGQ--- 206
                      S R+E + ++  SQ    + ++  RS  +V  L +     ++  S +   
Sbjct: 820  DS-----STTSGRSEESIASHSSQDATGTIVLPARSTNSVL-LGESTTSPISSGSMETTA 873

Query: 207  VHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCR 266
            + G  + P  S  +T F  S    PRS A+   +  S T S    E   +   P +T   
Sbjct: 874  LPGSTTTPGLSERSTTFHSS----PRSPATT-LSPASTTSSGVSEESTTSHSRPGSTHTT 928

Query: 267  EFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETP 326
             F D    +   P                  H+  + ++PG +          P+   T 
Sbjct: 929  AFPD----STTTPGL--------------SRHSTTSHSSPGSTDTTL-----LPASTTTX 965

Query: 327  RWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAE 386
              G P   P  S ++ + A        LP    +      S   Y  P R  ++    A 
Sbjct: 966  LVGEPTTSPISSGSTETTA--------LPGSTTTAGLSEKSTTFYSSP-RSPDTTLSPAS 1016

Query: 387  SMSDGVGSFLPGKMIVGRSDSTNSEDN----YVPMNPGSSTL--LAMERAGDNSQ--SVY 438
            + S GV             +ST S       +    PGS+T+  ++ E    +S   S  
Sbjct: 1017 TTSSGVSE-----------ESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD 1065

Query: 439  IPMSPGAHHFDSLGYPSTTLPVHRGPSRGS--------------EIQPPPVNRNLKPDRK 484
              +SP +    SLG  STT   H GP                  E   P  +    P   
Sbjct: 1066 TTLSPRSTTASSLGPESTTF--HSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTT 1123

Query: 485  AKPTPLDLRNNTVI---------DELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSIT 535
              P     R              D +P     T ++   + T + S S    P +  S +
Sbjct: 1124 LSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSI--PTTHFSAS 1181

Query: 536  STDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSV-DYLALDFQPSSPSPHRKP-- 592
            ST  G SEE+     +PV+    P+ T SPA   ++G V +  A    P S      P  
Sbjct: 1182 STTFGRSEESTTVHSSPVA----PATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPES 1237

Query: 593  STSSVTSDE 601
            ST+S  S+E
Sbjct: 1238 STASGRSEE 1246



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 84/358 (23%), Positives = 128/358 (35%), Gaps = 56/358 (15%)

Query: 293 TLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAAT--IPR 350
           TL  +H+A +V         P   P   +  ET           +SE S +  ++   P 
Sbjct: 158 TLFPSHSATSVFVG-----EPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPD 212

Query: 351 RNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNS 410
           R   PA   S      S  ++  P      A   + +M            I G +D+T S
Sbjct: 213 RTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLS 272

Query: 411 EDNYVP--MNPGSSTLLAME------RAGDNSQ-SVYIPMSPGAHHFDSLGYPSTTLPVH 461
                P  + P S+T  +        R  DN+  S  +  S   H   S G P TTL   
Sbjct: 273 PGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVH--SSTGSPHTTL--- 327

Query: 462 RGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSS 521
             P+  +  +  P      P  K              D  P  S  T ++ + + T++SS
Sbjct: 328 -SPASSTTHEGEPTTFQSWPSSK--------------DTSPAPSGTTSAFVKLSTTYHSS 372

Query: 522 SSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKST-GSVDYLALD 580
            S    P +  S +ST  G SEE+      PV +SPV + T  P  + +T G V+     
Sbjct: 373 PSS--TPTTHFSASSTTLGHSEES-----TPVHSSPVATATTPPPARSATSGHVE----- 420

Query: 581 FQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL 638
               S + HR P ++      +        E++     +    T   +SS PS  A L
Sbjct: 421 ---ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGS----TTHTKSSTPSTTAAL 471



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 115/551 (20%), Positives = 182/551 (33%), Gaps = 84/551 (15%)

Query: 92  NVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSN-HMQPTLSTSA 150
           N +++G    S+P   S+ S H      SS  +H  +PT F   P   +    P+ +TSA
Sbjct: 303 NTTTSGLLEASTPVHSSTGSPHTTLSPASST-THEGEPTTFQSWPSSKDTSPAPSGTTSA 361

Query: 151 PQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQK----LAQGNGHCVNGISGQ 206
              ++ L         +  +  FS  +         T V       A       +  SG 
Sbjct: 362 ---FVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGH 418

Query: 207 VHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLT--GSETDNEDVYTFKTPSNTL 264
           V         + H +     T   P S  + GH++ S T  GS T  +      TPS T 
Sbjct: 419 VE-----ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS----STPSTTA 469

Query: 265 CREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQA- 323
                     +  + +T  + ++   T +     +  + ++P   A    P    PS   
Sbjct: 470 ALAHTSY---HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLV 526

Query: 324 --ETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESA 381
              TP         PIS  S    A +P   T P +       +    T+    R  ++ 
Sbjct: 527 GDSTP--------SPISSGSMETTA-LPGSTTKPGL-------SEKSTTFYSSPRSPDTT 570

Query: 382 GRSAESMSDGVGSFLPGKMIVGRSDSTNSE----DNYVPMNPGSSTLLAMERAGDNSQSV 437
              A   S GV             +ST S       +    PGS+T+  + +    S S 
Sbjct: 571 HLPASMTSSGVS-----------EESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 619

Query: 438 YIP----MSPGAHHFDSLGYPSTT------------LPVHRGPSRGSEIQPPPVNRNLKP 481
             P    +SPG+    SLG   TT            LP +   S   E   P  +    P
Sbjct: 620 PGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP 679

Query: 482 DRKAKPTPLDLR--NNTVIDELPFK-----SPITKSWSRANHTFNSSSSQYCRPISTQSI 534
                P     R   +T     P       +P T + +    +  S  S    P +  S 
Sbjct: 680 HTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 739

Query: 535 TSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPST 594
            ST SG  EE+     +P S   +    + P    ++G  +        ++ +    PST
Sbjct: 740 RSTTSGLVEESTTYHSSPGSTQTM----HFPESDTTSGRGEESTTSHSSTTHTISSAPST 795

Query: 595 SSVTSDEKVDY 605
           +S   +E   Y
Sbjct: 796 TSALVEEPTSY 806



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 100/436 (22%), Positives = 157/436 (36%), Gaps = 74/436 (16%)

Query: 201 NGISGQVHGFYSLPKPSRHNTEFRDSTYDLP----RSLASHGH--------TKGSLTGSE 248
           +G+S +    +S P  S H T F  ST  +P     S ASH          + GS T S 
Sbjct: 579 SGVSEESTTSHSRPG-STHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASS 636

Query: 249 TDNEDVYTFKTPSNTLCREFGD------LLVDNMDVPATPLSAYQI--PRTFTLDKNHNA 300
              E       P +T      D      LL  +M V ++  S +    P   T  +  + 
Sbjct: 637 LGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST 696

Query: 301 MTVATPG--DSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMD 358
              + P   D+  APP       +  T   GSP   P    ++RS  + +   +T     
Sbjct: 697 TFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST----- 751

Query: 359 NSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMN 418
            +      S +T  +P+    ++GR  ES                 + S +S  + +   
Sbjct: 752 -TYHSSPGSTQTMHFPE-SDTTSGRGEES-----------------TTSHSSTTHTISSA 792

Query: 419 PGSSTLLAMERAGDNSQSVYIPMSPGAHHF----DSLGYPSTTLPVHRGPSRGSEIQPPP 474
           P +++ L  E    +S     P S    HF     + G    ++  H        I  P 
Sbjct: 793 PSTTSALVEEPTSYHSS----PGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPA 848

Query: 475 VNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSI 534
            + N     ++  +P+    +     LP  S  T   S  + TF+SS       +S  S 
Sbjct: 849 RSTNSVLLGESTTSPIS-SGSMETTALP-GSTTTPGLSERSTTFHSSPRSPATTLSPAST 906

Query: 535 TSTDSGDSEENYVPMQNPVS--ASPVPSGTNSPAPKK-------STGSVDYLALDFQPSS 585
           TS  SG SEE+      P S   +  P  T +P   +       S GS D   L   P+S
Sbjct: 907 TS--SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL---PAS 961

Query: 586 PSPH--RKPSTSSVTS 599
            +     +P+TS ++S
Sbjct: 962 TTTXLVGEPTTSPISS 977


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 85/358 (23%), Positives = 128/358 (35%), Gaps = 56/358 (15%)

Query: 293 TLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAAT--IPR 350
           TL  +H+A +V         P   P   +  ET           +SE S +  ++   P 
Sbjct: 93  TLFPSHSATSVFVG-----EPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPD 147

Query: 351 RNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNS 410
           R   PA   S      S  ++  P      A   + +M            I G +D+T S
Sbjct: 148 RTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLS 207

Query: 411 EDNYVP--MNPGSSTLLAME------RAGDNSQ-SVYIPMSPGAHHFDSLGYPSTTLPVH 461
                P  + P S+T  +        R  DN+  S  +  S   H   S G P TTL   
Sbjct: 208 PGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVH--SSTGSPHTTL--- 262

Query: 462 RGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSS 521
             PS  +  +  P      P  K              D  P  S  T ++ + + T++SS
Sbjct: 263 -SPSSSTTHEGEPTTFQSWPSSK--------------DTSPAPSGTTSAFVKLSTTYHSS 307

Query: 522 SSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKST-GSVDYLALD 580
            S    P +  S +ST  G SEE+      PV +SPV + T  P  + +T G V+     
Sbjct: 308 PSS--TPTTHFSASSTTLGHSEES-----TPVHSSPVATATTPPPARSATSGHVE----- 355

Query: 581 FQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL 638
               S + HR P ++      +        E++     +    T   +SS PS  A L
Sbjct: 356 ---ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGS----TTHTKSSTPSTTAAL 406



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 115/551 (20%), Positives = 183/551 (33%), Gaps = 84/551 (15%)

Query: 92  NVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSN-HMQPTLSTSA 150
           N +++G    S+P   S+ S H      SS+ +H  +PT F   P   +    P+ +TSA
Sbjct: 238 NTTTSGLLEASTPVHSSTGSPHTTLS-PSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA 296

Query: 151 PQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQK----LAQGNGHCVNGISGQ 206
              ++ L         +  +  FS  +         T V       A       +  SG 
Sbjct: 297 ---FVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGH 353

Query: 207 VHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLT--GSETDNEDVYTFKTPSNTL 264
           V         + H +     T   P S  + GH++ S T  GS T  +      TPS T 
Sbjct: 354 VE-----ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS----STPSTTA 404

Query: 265 CREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQA- 323
                     +  + +T  + ++   T +     +  + ++P   A    P    PS   
Sbjct: 405 ALAHTSY---HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLV 461

Query: 324 --ETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESA 381
              TP         PIS  S    A +P   T P +       +    T+    R  ++ 
Sbjct: 462 GDSTP--------SPISSGSMETTA-LPGSTTKPGL-------SEKSTTFYSSPRSPDTT 505

Query: 382 GRSAESMSDGVGSFLPGKMIVGRSDSTNSE----DNYVPMNPGSSTLLAMERAGDNSQSV 437
              A   S GV             +ST S       +    PGS+T+  + +    S S 
Sbjct: 506 HLPARMTSSGVS-----------EESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 554

Query: 438 YIP----MSPGAHHFDSLGYPSTT------------LPVHRGPSRGSEIQPPPVNRNLKP 481
             P    +SPG+    SLG   TT            LP +   S   E   P  +    P
Sbjct: 555 PGPTDTTLSPGSTTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTRSP 614

Query: 482 DRKAKPTPLDLR--NNTVIDELPFK-----SPITKSWSRANHTFNSSSSQYCRPISTQSI 534
                P     R   +T     P       +P T + +    +  S  S    P +  S 
Sbjct: 615 HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 674

Query: 535 TSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPST 594
            ST SG  EE+     +P S   +    + P    ++G  +        ++ +    PST
Sbjct: 675 RSTTSGLVEESTTYHSSPGSTQTM----HFPESDTTSGRGEESTTSHSSTTHTISSAPST 730

Query: 595 SSVTSDEKVDY 605
           +S   +E   Y
Sbjct: 731 TSALVEEPTSY 741



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 108/557 (19%), Positives = 190/557 (34%), Gaps = 86/557 (15%)

Query: 86  STDSLRNVSSAGHG-PRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQP 144
           +T +   +S+  H  P S+P    S+S   L   + S P HSS     T  PP       
Sbjct: 293 TTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPP------- 345

Query: 145 TLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGIS 204
                                  ARSA+      ++   RS  + Q +        +G S
Sbjct: 346 -----------------------ARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHS 382

Query: 205 GQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTK--GSLTGSETDNEDVYTFKTPSN 262
            +   F+     ++ +T         P + A+  HT    SL  +ET      T    S+
Sbjct: 383 EESATFHGSTTHTKSST---------PSTTAALAHTSYHSSLGSTET------THFRDSS 427

Query: 263 TLCREFGDLLVDNMDVPA---TPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPK 319
           T+     +    +    A   T L A   P     D   + ++  +   +A+      P 
Sbjct: 428 TISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG 487

Query: 320 PSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGE 379
            S+  T  + SP+        +R  ++ +   +T         H  +   +   P    E
Sbjct: 488 LSEKSTTFYSSPRSPDTTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE 547

Query: 380 SA------GRSAESMSDG--VGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLL-AMERA 430
           S       G +  ++S G    S L  +     S   ++E   +P N  +S LL A    
Sbjct: 548 STASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPV 607

Query: 431 GDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPL 490
             +++S +  +SP      S      +   H  PS       PP             T  
Sbjct: 608 HSSTRSPHTTLSPAG----STTRQGESTTFHSWPSSKDTRPAPPTT-----------TSA 652

Query: 491 DLRNNTVIDELPFKSPITKSWSRANHT--FNSSSSQYCRPISTQSI----TSTDSGDSEE 544
            +  +T     P   P T   +R+  +     S++ +  P STQ++    + T SG  EE
Sbjct: 653 FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 712

Query: 545 ---NYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQP--SSPSPHRKPSTSSVTS 599
              ++    + +S++P  +      P     S    A    P  S+ S   + ST+S +S
Sbjct: 713 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 772

Query: 600 DEKVDYVQVDKEKTQAL 616
            +    + +    T ++
Sbjct: 773 QDATGTIVLPARSTNSV 789


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 127/568 (22%), Positives = 195/568 (34%), Gaps = 96/568 (16%)

Query: 95   SAGHGPRSSPAELSSSSQHLLRERKSSAPS----HSSQPTLFTFEPPVSNHMQPTLSTSA 150
            SAGH   S+   L SS+  L  E K SA S    H +  ++ T  P +S   +P+   SA
Sbjct: 714  SAGHTKISTSIPLLSSASVL--EDKVSATSTFSHHKATSSITTGTPEISTKTKPS---SA 768

Query: 151  PQEYLYLHQCIS--RRAENARSA----SFSQGTRASFLMRSDTAVQKLAQGNGHCVNGI- 203
                + L    +   R  NA S     S S    A  ++   T+ +     N H    + 
Sbjct: 769  VLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLT 828

Query: 204  --SGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPS 261
              S +     SLP  S   T F  ST       ++H  T G  T  ET N  V     P 
Sbjct: 829  SESSESPSTLSLPSVSGVKTTFSSSTP------STHLFTSGEET-EETSNPSV---SQPE 878

Query: 262  NTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRP--PK 319
             ++ R    L   ++  P  P       R+     +H    +     +++        PK
Sbjct: 879  TSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPK 938

Query: 320  PSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGE 379
             S        S   R   ++++   + T P   T P          ++  T         
Sbjct: 939  ISHLTGTATMSQTNRDTFNDSAAPQSTTWPE--TSPRFKTGLPSATTTVST--------- 987

Query: 380  SAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYI 439
                SA S+S  V       M+   +    S      +   S+T+L  E           
Sbjct: 988  ----SATSLSATV-------MVSKFTSPATSSMEATSIREPSTTILTTETTN-------- 1028

Query: 440  PMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVID 499
               PG     S+   ST +P+ +G      +           D    P      + T +D
Sbjct: 1029 --GPG-----SMAVASTNIPIGKGYITEGRL-----------DTSHLPIGTTASSETSMD 1070

Query: 500  ELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGD-----SEENYVPMQNPVS 554
                K  ++ S S +     + SS    P  T     T S D     S E  +P     S
Sbjct: 1071 FTMAKESVSMSVSPSQSMDAAGSST---PGRTSQFVDTFSDDVYHLTSREITIPRDGTSS 1127

Query: 555  A-SPVPSGTNSPAPKKSTGSVDYLA-LDFQPSSPSP----HRKPSTSSVTSDEKVDYVQV 608
            A +P  + T+ P+P   +    +L  L   PSSP+P        ST  VT+   +D V+ 
Sbjct: 1128 ALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVET 1187

Query: 609  DKEKTQALQNTMQEWTDVRQSSEPSKGA 636
             +     L +T    T +  S+ P+ GA
Sbjct: 1188 SRWNMPNLPST----TSLTPSNIPTSGA 1211



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 71/327 (21%), Positives = 122/327 (37%), Gaps = 42/327 (12%)

Query: 303  VATPGDSAIAPPPRPPKPSQ-----AETPRWGSPQQRPPISENSRSVAATIPRRNTLPAM 357
            + T   S++ P  R  + S+      ET    S       +E SR+   T   R T+   
Sbjct: 5772 IQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVIT-SSRTTISGP 5830

Query: 358  DNSRLHRASSCETYE----YPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDN 413
            D+S++    S ET      +P   G S   +  + +  +G+     + +  S + + E  
Sbjct: 5831 DHSKMSPYISTETITRLSTFPFVTG-STEMAITNQTGPIGTISQATLTLDTSSTASWEGT 5889

Query: 414  YVPMN---PGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPV---------H 461
            + P+    P S     M R+   ++ V     P      S   PS+ +P+         +
Sbjct: 5890 HSPVTQRFPHSEETTTMSRS---TKGVSWQSPPSVEETSS---PSSPVPLPAITSHSSLY 5943

Query: 462  RGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSS 521
               S  S     PV   L   R+     LD  +  V   LP  S  +     +  + N+ 
Sbjct: 5944 SAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTE 6003

Query: 522  SSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSV--DYLAL 579
            +  +     +++   T+ G +   +  + + VS    PSG     P K TGS+  D +  
Sbjct: 6004 TIHF-----SENTAETNMGTTNSMH-KLHSSVSIHSQPSG---HTPPKVTGSMMEDAIVS 6054

Query: 580  DFQPSSPSPHR--KPSTSSVTSDEKVD 604
               P SP      + STS +T + K D
Sbjct: 6055 TSTPGSPETKNVDRDSTSPLTPELKED 6081


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 127/551 (23%), Positives = 194/551 (35%), Gaps = 78/551 (14%)

Query: 86   STDSLRNVSSAGH-GPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQP 144
            +T SL   S+  +  PRS  A LS ++       + S+ SHS   +  T   P S     
Sbjct: 919  TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS----- 973

Query: 145  TLSTSAPQEYLYLHQCISRRAENARSASFSQG-TRASFLMRSDTAVQKLAQGNGHCVNGI 203
            T ++   QE    H      ++ +  A+ S G T AS L +  T            +   
Sbjct: 974  TTTSDLSQEPTTSHS-----SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 1028

Query: 204  SGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNT 263
                 G      P+  +T    +T   P S  S G  + S T     +    T  +P  T
Sbjct: 1029 DTITSGLVEASTPTHSSTGSLHTTLT-PASSTSAGLQEESTTFQSWPSSSDTT-PSPPGT 1086

Query: 264  LCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTV-ATPGDSAIAPPPRPPKPSQ 322
                       +    +TP + +    T TL ++  + TV ++PG +  A  P       
Sbjct: 1087 TAAPVEVSTTYHSRPSSTPTTHFSASST-TLGRSEESTTVHSSPGATGTALFPT----RS 1141

Query: 323  AETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAG 382
            A +   G P   P  S ++ + A        LP    +      S   Y  P R  ++  
Sbjct: 1142 ATSVLVGEPTTSPISSGSTETTA--------LPGSTTTAGLSEKSTTFYSSP-RSPDTTL 1192

Query: 383  RSAESMSDGVGSFLPGKMIVGRSDSTNSEDN----YVPMNPGSSTL--LAMERAGDNSQ- 435
              A + S GV             +ST S       +    PGS+T+  ++ E    +S  
Sbjct: 1193 SPASTTSSGVSE-----------ESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1241

Query: 436  -SVYIPMSPGAHHFDSLGYPSTT------------LPVHRGPSRGSEIQPPPVNRNLKPD 482
             S    +SPG+    SLG  STT            LP +   S   E   P  +    P 
Sbjct: 1242 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPH 1301

Query: 483  RKAKPTPLDLRNNTVI---------DELPFKSPITKSWSRANHTFNSSSSQYCRPISTQS 533
                P     R              D +P     T ++   + T + S S    P +  S
Sbjct: 1302 TTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSS--TPTTHFS 1359

Query: 534  ITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSV-DYLALDFQPSSPSPHRKP 592
             +ST  G SEE+     +PV+ +  P    SPA   ++G V +  A    P S      P
Sbjct: 1360 ASSTTLGRSEESTTVHSSPVATATTP----SPARSTTSGLVEESTAYHSSPGSTQTMHFP 1415

Query: 593  --STSSVTSDE 601
              ST+S  S+E
Sbjct: 1416 ESSTASGRSEE 1426



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 100/437 (22%), Positives = 151/437 (34%), Gaps = 75/437 (17%)

Query: 201 NGISGQVHGFYSLPKPSRHNTEFRDSTYDLP----RSLASHGH--------TKGSLTGSE 248
           +G+S +    +S P  S H T F  ST  +P     S ASH          + GS T S 
Sbjct: 145 SGVSEESTTSHSRPG-STHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASS 202

Query: 249 TDNEDVYTFKTPSNTLCREFGD------LLVDNMDVPATPLSAYQI--PRTFTLDKNHNA 300
              E       P +T      D      LL  +M V ++  S +    P   T  +  + 
Sbjct: 203 LGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST 262

Query: 301 MTVATPG--DSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMD 358
              + P   D+  APP       +  T   GSP   P    ++RS  + +   +T     
Sbjct: 263 TFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST----- 317

Query: 359 NSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMN 418
            +      S +T  +P+    ++GR  ES                 + S +S  + +   
Sbjct: 318 -TYHSSPGSTQTMHFPE-SDTTSGRGEES-----------------TTSHSSTTHTISSA 358

Query: 419 PGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRN 478
           P +++ L  E    +S     P S    HF      S+T       S  S          
Sbjct: 359 PSTTSALVEEPTSYHSS----PGSTATTHFPD----SSTTSGRSEESTASHSSQDATGTI 410

Query: 479 LKPDRKAKPTPLDLRNNTVIDE-------LPFKSPITKSWSRANHTFNSSSSQYCRPIST 531
           + P R      L     + I         LP  S  T   S  + TF+SS       +S 
Sbjct: 411 VLPARSTTSVLLGESTTSPISSGSMETTALP-GSTTTPGLSERSTTFHSSPRSPATTLSP 469

Query: 532 QSITSTDSGDSEENYVPMQNPVS--ASPVPSGTNSPAPKK-------STGSVDYLALDFQ 582
            S TS  SG SEE+      P S   +  P  T +P   +       S GS D   L   
Sbjct: 470 ASTTS--SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 527

Query: 583 PSSPSPHRKPSTSSVTS 599
            ++  P ++ +TS  +S
Sbjct: 528 TTTSGPSQESTTSHSSS 544


>gi|169214023 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 193

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 22/120 (18%)

Query: 306 PGDSAIAPPPR---PPKPSQAETPR-WGSPQQRPPISENSRSVAATIPRRNTLPAMDNSR 361
           P  SA  P P    PP+P     PR WG+P  RP +      + A  P            
Sbjct: 62  PPSSAAPPTPHSSIPPRPPSPWGPRVWGAPTHRPALKGTEAQLLAPGPAAG--------- 112

Query: 362 LHRASSCETYEYPQRGG-ESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG 420
               S C    +P+  G ESA    E    G  S  P   ++    ST +   + P NPG
Sbjct: 113 ----SGC----WPELAGTESASAEREREGGGPRSIRPRPSLLSSGHSTRAPGLHPPRNPG 164


>gi|169214468 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 193

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 22/120 (18%)

Query: 306 PGDSAIAPPPR---PPKPSQAETPR-WGSPQQRPPISENSRSVAATIPRRNTLPAMDNSR 361
           P  SA  P P    PP+P     PR WG+P  RP +      + A  P            
Sbjct: 62  PPSSAAPPTPHSSIPPRPPSPWGPRVWGAPTHRPALKGTEAQLLAPGPAAG--------- 112

Query: 362 LHRASSCETYEYPQRGG-ESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPG 420
               S C    +P+  G ESA    E    G  S  P   ++    ST +   + P NPG
Sbjct: 113 ----SGC----WPELAGTESASAEREREGGGPRSIRPRPSLLSSGHSTRAPGLHPPRNPG 164


>gi|39995080 hypothetical protein LOC79567 [Homo sapiens]
          Length = 1219

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 66/300 (22%), Positives = 103/300 (34%), Gaps = 40/300 (13%)

Query: 314 PPRPPKPSQAETPRWGSPQQRPPISENSRSVAAT--IPRR-NTLPAMDNSRLHRASSCET 370
           PP  P P+  E P    P   P  S  S ++  T  +P   +  P+     +H+++    
Sbjct: 479 PPTHPAPTHGEHPSPVPPALDPGHSATSSTLGTTGSVPTSTDPAPSAHLDSVHKSTDSGP 538

Query: 371 YEYPQRGGESAGR--SAESMSDGVGSFL--------------------PGKMIVGRSDST 408
            E P     + G   SA + +    S L                    P   I+G   +T
Sbjct: 539 SELPGPTHTTTGSTYSAITTTHSAPSPLTHTTTGSTHKPIISTLTTTGPTLNIIGPVQTT 598

Query: 409 NSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGS 468
            S  + +P    S T         ++   + P SP   H  S+  P+TT P   G     
Sbjct: 599 TSPTHTMP----SPTHTTASPTHTSTSPTHTPTSPT--HKTSMSPPTTTSPTPSGMGLVQ 652

Query: 469 EIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRP 528
               P             P  +++  +T ++     SP   S    + T   + S  C P
Sbjct: 653 TATSPTHPTTSPTHPTTSPILINVSPSTSLELATLSSPSKHS----DPTLPGTDSLPCSP 708

Query: 529 ISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSP 588
             + S T  D         P  +P  +S  P    SPAP  S  +V  L+    P +P+P
Sbjct: 709 PVSNSYTQADPMAPR---TPHPSPAHSSRKP--LTSPAPDPSESTVQSLSPTPSPPTPAP 763


>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
          Length = 2186

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 24/122 (19%)

Query: 7   VLEYYKNDH-SKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFY-LVAETE 64
           ++ +YK++  SK+P   I L+ C  V       K      + F++K ++ T++ L AETE
Sbjct: 222 IMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRK------YAFELKMNDLTYFVLAAETE 275

Query: 65  EDMNKWVQSICQIC-----GFNQAEEST-------DSLRNVSSAGHGPRSSPAELSSSSQ 112
            DM++W+ ++ +I      G  Q   ST       DSL N  +       +P E  SS  
Sbjct: 276 SDMDEWIHTLNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTC----ECTPEETDSSEN 331

Query: 113 HL 114
           +L
Sbjct: 332 NL 333


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 12/110 (10%)

Query: 502 PFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPV-------S 554
           P +SP++   S  + + + SS     P ST S  S  S +S     P+Q+PV       S
Sbjct: 809 PLQSPVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPES-----PLQSPVISFSSSTS 863

Query: 555 ASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVD 604
            SP    ++SP  + ++ S   L  D    S S        + T DEKVD
Sbjct: 864 LSPFSEESSSPVDEYTSSSDTLLESDSLTDSESLIESEPLFTYTLDEKVD 913


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 38.1 bits (87), Expect = 0.025
 Identities = 79/347 (22%), Positives = 124/347 (35%), Gaps = 27/347 (7%)

Query: 302  TVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSR 361
            +V  P    + PP  P  P     P   S      +S    +     P +  +P   N+ 
Sbjct: 1045 SVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTP 1104

Query: 362  LHRASSCETY-EYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSE----DNYVP 416
            L   S    Y E PQ    S      S+ +  GS  P   + G  ++  S      N + 
Sbjct: 1105 LGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPS--VPGGPNNMPSHVVLPQNQLM 1162

Query: 417  MN---PGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPP 473
            M    PG S L A + A      V    S   HHF ++  P+ T    + P+R S     
Sbjct: 1163 MTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQT-SRPKTPNRASPRPYY 1221

Query: 474  PVNRNLKPDRKAKPTPLDL---RNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPIS 530
            P   N +P    +P+ + L   R N  I  L F   I        +       Q   P +
Sbjct: 1222 PQTPNNRPP-STEPSEISLSPERLNASIAGL-FPPQINIPLPPRPNLNRGFDQQGLNPTT 1279

Query: 531  TQSITSTDSG---DSEENYVPMQNPVSASPVPSG--TNSPAPKKSTGSVDYLALDFQPSS 585
             ++I    S    +      P  + + +  V SG  +NS A K+++ S      + + SS
Sbjct: 1280 LKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPS------NSRRSS 1333

Query: 586  PSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEP 632
            P   RK + S    + K   + +  +   AL   ++   +V  S  P
Sbjct: 1334 PGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1380


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,996,760
Number of Sequences: 37866
Number of extensions: 1587356
Number of successful extensions: 9628
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 309
Number of HSP's that attempted gapping in prelim test: 8498
Number of HSP's gapped (non-prelim): 1280
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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