Guide to the Human Genome
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Search of human proteins with 68989258

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68989258 neurogenin 3 [Homo sapiens]
         (214 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68989258 neurogenin 3 [Homo sapiens]                               437   e-123
gi|38455396 neurogenin 1 [Homo sapiens]                               143   1e-34
gi|31077092 neurogenin 2 [Homo sapiens]                               127   5e-30
gi|27475985 neurogenic differentiation 6 [Homo sapiens]                87   8e-18
gi|98986461 neurogenic differentiation 2 [Homo sapiens]                86   2e-17
gi|121114306 neurogenic differentiation 1 [Homo sapiens]               82   4e-16
gi|153792190 neurogenic differentiation 4 [Homo sapiens]               80   1e-15
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    76   2e-14
gi|4885075 atonal homolog 1 [Homo sapiens]                             74   7e-14
gi|21553337 atonal homolog 7 [Homo sapiens]                            70   1e-12
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]      67   1e-11
gi|148922889 scleraxis homolog B [Homo sapiens]                        64   1e-10
gi|186972126 scleraxis homolog A [Homo sapiens]                        64   1e-10
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    64   1e-10
gi|57529222 basic helix-loop-helix domain containing, class B, 4...    61   6e-10
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    60   1e-09
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    60   2e-09
gi|116805332 musculin [Homo sapiens]                                   60   2e-09
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]         60   2e-09
gi|17981708 twist homolog 2 [Homo sapiens]                             58   7e-09
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]                58   7e-09
gi|23097242 nephew of atonal 3 [Homo sapiens]                          58   7e-09
gi|4507741 twist [Homo sapiens]                                        57   2e-08
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]     57   2e-08
gi|38202237 transcription factor 21 [Homo sapiens]                     56   2e-08
gi|38202239 transcription factor 21 [Homo sapiens]                     56   2e-08
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    55   3e-08
gi|226498192 atonal homolog 8 [Homo sapiens]                           55   6e-08
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo...    55   6e-08
gi|14149724 mesoderm posterior 1 [Homo sapiens]                        55   6e-08

>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score =  437 bits (1124), Expect = e-123
 Identities = 214/214 (100%), Positives = 214/214 (100%)

Query: 1   MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRK 60
           MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRK
Sbjct: 1   MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRK 60

Query: 61  LRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLT 120
           LRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLT
Sbjct: 61  LRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLT 120

Query: 121 KIETLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAG 180
           KIETLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAG
Sbjct: 121 KIETLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAG 180

Query: 181 SLSPAASLEERPGLLGATFSACLSPGSLAFSDFL 214
           SLSPAASLEERPGLLGATFSACLSPGSLAFSDFL
Sbjct: 181 SLSPAASLEERPGLLGATFSACLSPGSLAFSDFL 214


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score =  143 bits (361), Expect = 1e-34
 Identities = 90/173 (52%), Positives = 103/173 (59%), Gaps = 14/173 (8%)

Query: 34  SAPPSPTRTRG--NCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDR 91
           S PP+P R RG  N + A E        + R RR GR+R +SE  L   RRSRR KANDR
Sbjct: 42  SGPPAPAR-RGAPNISRASEVPGAQDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDR 100

Query: 92  ERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSL----- 146
           ERNRMHNLN+ALDALR VLP+FPDD KLTKIETLRFA+NYIWAL +TLR+AD  L     
Sbjct: 101 ERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGA 160

Query: 147 -YALEPP--APHCGELGSPGGSPGDWGS---LYSPVSQAGSLSPAASLEERPG 193
              L PP   P      SP      WGS     SP+S   S + +     RPG
Sbjct: 161 RERLLPPQCVPCLPGPPSPASDAESWGSGAAAASPLSDPSSPAASEDFTYRPG 213


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score =  127 bits (320), Expect = 5e-30
 Identities = 92/200 (46%), Positives = 109/200 (54%), Gaps = 46/200 (23%)

Query: 43  RGNCAEAEEGGCRGAP----------RKLRARRGGRSRPKSELALSKQRRSRRKKANDRE 92
           RG  A   EG CR A           R  RAR   R    +E  + + +++RR KAN+RE
Sbjct: 64  RGGVAAGAEG-CRPARLLGLVHDCKRRPSRARAVSRGAKTAE-TVQRIKKTRRLKANNRE 121

Query: 93  RNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLYALEPP 152
           RNRMHNLN+ALDALR VLPTFP+DAKLTKIETLRFAHNYIWALT+TLR+AD         
Sbjct: 122 RNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLAD--------- 172

Query: 153 APHCGELG--------------SPGG------SPGDWGSLYSPVSQAGSLSPAASLEERP 192
             HCG  G              SPGG      S GD  S  S  S   S +P++S+    
Sbjct: 173 --HCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230

Query: 193 GLLGATFSACLSPGSLAFSD 212
               + +S  LSP S A SD
Sbjct: 231 ---TSPYSCTLSPASPAGSD 247


>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
          Length = 337

 Score = 87.4 bits (215), Expect = 8e-18
 Identities = 52/107 (48%), Positives = 65/107 (60%), Gaps = 5/107 (4%)

Query: 35  APPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERN 94
           AP   T       + EE    G PR    RRG R +  ++L L + +  RR++AN RERN
Sbjct: 51  APGEETEKEEEEEDREEEDENGLPR----RRGLRKKKTTKLRLERVK-FRRQEANARERN 105

Query: 95  RMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRI 141
           RMH LN ALD LR V+P +    KL+KIETLR A NYIWAL++ LRI
Sbjct: 106 RMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRI 152


>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
          Length = 382

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 47/93 (50%), Positives = 62/93 (66%), Gaps = 1/93 (1%)

Query: 48  EAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALR 107
           E EE G   A  +   +RG + R  ++  L + +  RR+KAN RERNRMH+LN+ALD LR
Sbjct: 87  EEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKL-RRQKANARERNRMHDLNAALDNLR 145

Query: 108 GVLPTFPDDAKLTKIETLRFAHNYIWALTQTLR 140
            V+P +    KL+KIETLR A NYIWAL++ LR
Sbjct: 146 KVVPCYSKTQKLSKIETLRLAKNYIWALSEILR 178


>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
          Length = 356

 Score = 81.6 bits (200), Expect = 4e-16
 Identities = 42/79 (53%), Positives = 54/79 (68%)

Query: 62  RARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTK 121
           + +R G  + K   A  ++ + RR KAN RERNRMH LN+ALD LR V+P +    KL+K
Sbjct: 80  KPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSK 139

Query: 122 IETLRFAHNYIWALTQTLR 140
           IETLR A NYIWAL++ LR
Sbjct: 140 IETLRLAKNYIWALSEILR 158


>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
          Length = 331

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 41/78 (52%), Positives = 52/78 (66%)

Query: 62  RARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTK 121
           + +R G  + K   A  ++ R+RR KAN RER RMH LN ALD LR V+P +    KL+K
Sbjct: 66  KPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSK 125

Query: 122 IETLRFAHNYIWALTQTL 139
           IETLR A NYIWAL++ L
Sbjct: 126 IETLRLARNYIWALSEVL 143


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 57/133 (42%), Positives = 70/133 (52%), Gaps = 6/133 (4%)

Query: 24  ASEDEVTCPTSAP-PSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRR 82
           A+  E T   S P P P   +G  +       R AP + R RR G S P      S QRR
Sbjct: 19  ATPGEGTPDGSLPNPGPEPAKGLRSRPARAAAR-APGEGRRRRPGPSGPGGRRDSSIQRR 77

Query: 83  SRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQT-LRI 141
               ++N+RER RMH LN+A  ALR V+P    D KL+KIETL  A NYI +LT T L +
Sbjct: 78  L---ESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTM 134

Query: 142 ADHSLYALEPPAP 154
           +   L  LE P P
Sbjct: 135 SSSRLPGLEGPGP 147


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 74.3 bits (181), Expect = 7e-14
 Identities = 63/196 (32%), Positives = 84/196 (42%), Gaps = 28/196 (14%)

Query: 34  SAPPSPTRTRGNCAEAEEGGCRGA----PRKLRAR----RGG---------RSRPKSELA 76
           +AP      RG       GG   +    P K+R +    +GG         R R  S   
Sbjct: 93  AAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQ 152

Query: 77  LSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALT 136
           ++  ++ RR  AN RER RMH LN A D LR V+P+F +D KL+K ETL+ A  YI AL+
Sbjct: 153 VNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALS 212

Query: 137 QTLRIADHSLYALEPPAP------HCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEE 190
           + L+          PPA       H     S  G  G+  +  +  +  GS  P      
Sbjct: 213 ELLQTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQASGGSQRPTP---- 268

Query: 191 RPGLLGATFSACLSPG 206
            PG     FSA  S G
Sbjct: 269 -PGSCRTRFSAPASAG 283


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 55/153 (35%), Positives = 66/153 (43%), Gaps = 26/153 (16%)

Query: 30  TCPTSAPPSPTRTRGNCAEAEE--GGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKK 87
           +C  S PP+  R    CA   E  G C GA R   A R                  RR  
Sbjct: 3   SCKPSGPPAGARVAPPCAGGTECAGTCAGAGRLESAAR------------------RRLA 44

Query: 88  ANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLY 147
           AN RER RM  LN+A D LR V+P +  D KL+K ETL+ A +YI ALT+ L  A+    
Sbjct: 45  ANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGS 104

Query: 148 ALEPPAPHCGELGS------PGGSPGDWGSLYS 174
             +    HC   G       PG        LYS
Sbjct: 105 ERDWVGLHCEHFGRDHYLPFPGAKLPGESELYS 137


>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
          Length = 272

 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 47/117 (40%), Positives = 59/117 (50%), Gaps = 6/117 (5%)

Query: 66  GGRSRPKSELALSKQRRSR-RKKANDRERNRMHNLNSALDALRGVLPTF--PDDAKLTKI 122
           G  S+ K +  LS+Q   + R K N RER RMH+LN A+D LR V+P    P   KL+KI
Sbjct: 65  GESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKI 124

Query: 123 ETLRFAHNYIWALTQTLRIADH---SLYALEPPAPHCGELGSPGGSPGDWGSLYSPV 176
            TL  A NYI  LT +L         +Y     A HCG +G   G P    +   PV
Sbjct: 125 ATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPV 181


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 53/160 (33%), Positives = 73/160 (45%), Gaps = 22/160 (13%)

Query: 25  SEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSR 84
           SEDE     S+       R + A     G +GA R+   RR G   P        ++R  
Sbjct: 23  SEDEDRGSDSSGSDEKPCRVHAARC---GLQGARRRAGGRRAGGGGPGGRPGREPRQRHT 79

Query: 85  RKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADH 144
              AN RER+R +++N+A  ALR ++PT P D KL+KIETLR A +YI  L   L   + 
Sbjct: 80  ---ANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE- 135

Query: 145 SLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLSP 184
                      CG+     G P   G  +   ++AGS  P
Sbjct: 136 ----------ACGD-----GQPCHSGPAFFHAARAGSPPP 160


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 53/160 (33%), Positives = 73/160 (45%), Gaps = 22/160 (13%)

Query: 25  SEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSR 84
           SEDE     S+       R + A     G +GA R+   RR G   P        ++R  
Sbjct: 23  SEDEDRGSDSSGSDEKPCRVHAARC---GLQGARRRAGGRRAGGGGPGGRPGREPRQRHT 79

Query: 85  RKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADH 144
              AN RER+R +++N+A  ALR ++PT P D KL+KIETLR A +YI  L   L   + 
Sbjct: 80  ---ANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE- 135

Query: 145 SLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLSP 184
                      CG+     G P   G  +   ++AGS  P
Sbjct: 136 ----------ACGD-----GQPCHSGPAFFHAARAGSPPP 160


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 40/98 (40%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 46  CAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDA 105
           C E  E   RG P     RR G       + + +QR++    AN RER+R  ++N+A  A
Sbjct: 40  CCEGPEAARRG-PGPGGGRRAGGGGGAGPVVVVRQRQA----ANARERDRTQSVNTAFTA 94

Query: 106 LRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIAD 143
           LR ++PT P D KL+KIETLR A +YI  L   L + D
Sbjct: 95  LRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGD 132


>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score = 61.2 bits (147), Expect = 6e-10
 Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 16/113 (14%)

Query: 35  APPSPTRTRGNCAEAEEGGCRGAPRKLRARRG------GRSRPKSELALSKQRRSRRKKA 88
           AP +P +   +  E + G    A  + R RRG      GR RP+       ++RS R   
Sbjct: 54  APRAPAQAAESSGE-QSGDEDDAFEQRRRRRGPGSAADGRRRPR-------EQRSLRLSI 105

Query: 89  NDRERNRMHNLNSALDALRGVLP--TFPDDAKLTKIETLRFAHNYIWALTQTL 139
           N RER RMH+LN ALD LR V+P    P   KL+KI TL  A NYI    Q L
Sbjct: 106 NARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 158


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 55/174 (31%), Positives = 77/174 (44%), Gaps = 25/174 (14%)

Query: 31  CPTSAPPS---------PTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQR 81
           C T APP          P+     CA A         R L       +R +  +    + 
Sbjct: 102 CETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAEL 161

Query: 82  RSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRI 141
           +  R+ AN RER RM ++N A + LR  +PT P + +L+K++TLR A  YI  L++ ++ 
Sbjct: 162 QQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ- 220

Query: 142 ADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQA--------GSLSPAAS 187
           AD  L      A  CG  G  G   GD     SP SQA        G+ SP+ S
Sbjct: 221 ADLPLRG--GGAGGCGGPGGGGRLGGD-----SPGSQAQKVIICHRGTRSPSPS 267


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 51/144 (35%), Positives = 65/144 (45%), Gaps = 13/144 (9%)

Query: 66  GGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLP--TFPDDAKLTKIE 123
           G  S   S    SK++++ R   N RER RMH+LN ALD LR V+P    P   KL+KI 
Sbjct: 225 GSSSSSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIA 284

Query: 124 TLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLS 183
           TL  A NYI    Q L      +  L       G+  S    P    S  +  + A +L 
Sbjct: 285 TLLLAKNYILMQAQALEEMRRLVAYLNQ-----GQAISAASLP----SSAAAAAAAAALH 335

Query: 184 PAASLEERPGLLGATFSACLSPGS 207
           PA    E+    G  FSA L P +
Sbjct: 336 PALGAYEQAA--GYPFSAGLPPAA 357


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 43/137 (31%), Positives = 64/137 (46%), Gaps = 15/137 (10%)

Query: 15  RETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKL-----------RA 63
           R  ERS+   S++     ++    P      CA    G   G  RK             A
Sbjct: 32  RGVERSYASPSDNS----SAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSA 87

Query: 64  RRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIE 123
             GG+    ++ + ++ ++S+R  AN RER RM  L+ A   L+  LP  P D KL+K++
Sbjct: 88  GGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLD 147

Query: 124 TLRFAHNYIWALTQTLR 140
           TLR A +YI  L Q L+
Sbjct: 148 TLRLASSYIAHLRQLLQ 164


>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
          Length = 193

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 65/195 (33%), Positives = 83/195 (42%), Gaps = 18/195 (9%)

Query: 27  DEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRK 86
           D  T P SAPP+P    G  A         +P  LR  R  R RP +  A +    +   
Sbjct: 2   DGGTLPRSAPPAPPVPVGCAARRRPA----SPELLRCSR--RRRPAT--AETGGGAAAVA 53

Query: 87  KANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSL 146
           + N+RERNR+  +N    ALR  +P      KL+K+ETLR A  YI AL + L   D   
Sbjct: 54  RRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVR 113

Query: 147 YALEPP-APHCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEERPGLLGATFSA---- 201
            AL     P      +P G PG      SP S+A S SP       PG   + +S+    
Sbjct: 114 NALAGGLRPQAVRPSAPRGPPGTTPVAASP-SRASS-SPGRGGSSEPGSPRSAYSSDDSG 171

Query: 202 ---CLSPGSLAFSDF 213
               LSP      DF
Sbjct: 172 CEGALSPAERELLDF 186


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 45/119 (37%), Positives = 62/119 (52%), Gaps = 12/119 (10%)

Query: 33  TSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARR----------GGRSRPKSELALS-KQR 81
           +S+P SP  + G   E  E   +   RK R  +          G R +  S  A S ++ 
Sbjct: 5   SSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEEL 64

Query: 82  RSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLR 140
           +S+R  AN RER R  +LN A  ALR ++PT P D KL+KI+TL+ A  YI  L Q L+
Sbjct: 65  QSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 122


>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
          Length = 397

 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 49/143 (34%), Positives = 69/143 (48%), Gaps = 18/143 (12%)

Query: 33  TSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSR-------R 85
           +++P S + + G+C      G RG P+        R+   +E A +  RR+R       R
Sbjct: 30  STSPASSSDSSGSCPC---DGARGLPQPQPPSCSSRA---AEAAATTPRRARTGPAGGQR 83

Query: 86  KKANDRERNRMHNLNSALDALRGVLPTF--PDDAKLTKIETLRFAHNYIWALTQTLRIAD 143
           + A++RE+ RM  L  AL  LR  LP    P    LTKIETLR A  YI  L+  L +++
Sbjct: 84  QSASEREKLRMRTLARALHELRRFLPPSLAPAGQSLTKIETLRLAIRYIGHLSAVLGLSE 143

Query: 144 HSLYALEPPAPHCGELGSPGGSP 166
            SL          G+ GSP G P
Sbjct: 144 ESLQCRRRQR---GDAGSPWGCP 163


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 35/76 (46%), Positives = 47/76 (61%), Gaps = 4/76 (5%)

Query: 68  RSRPKSELALSKQRR----SRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIE 123
           R R  S L   K++R    ++R+ AN RER RM NLN A D LR  +PTF  + +L++IE
Sbjct: 82  RGRGVSLLGRPKRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIE 141

Query: 124 TLRFAHNYIWALTQTL 139
           TLR A  YI  +T+ L
Sbjct: 142 TLRLAIVYISFMTELL 157


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 6/105 (5%)

Query: 36  PPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNR 95
           P SP + +     A  GG  GA     +  GG S    E     + +++R  AN RER R
Sbjct: 66  PGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYE-----ELQTQRVMANVRERQR 120

Query: 96  MHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLR 140
             +LN A  ALR ++PT P D KL+KI+TL+ A  YI  L Q L+
Sbjct: 121 TQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 164


>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
          Length = 271

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 59/202 (29%), Positives = 82/202 (40%), Gaps = 38/202 (18%)

Query: 3   PQPSGAPTVQVTRETERS------FPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRG 56
           P  S + +   T  T  S       P+A+ ++   P   PP P    G            
Sbjct: 41  PPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAE-PPGPGPGSG------------ 87

Query: 57  APRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTF--- 113
                 A  GG +RP ++    +Q++  R+K N RER RM +LN A+DALR V+  +   
Sbjct: 88  ------AHPGGSARPDAK---EEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAA 138

Query: 114 ----PDDAKLTKIETLRFAHNYIWALTQTLRIADHSL-YALEPPAPHCGELGSP--GGSP 166
                   KL+KI TL  A NYI  L  +L+    +L     P AP     G P    +P
Sbjct: 139 HCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAP 198

Query: 167 GDWGSLYSPVSQAGSLSPAASL 188
           G        V    +L PA  L
Sbjct: 199 GSVLLAPGAVGPPDALRPAKYL 220


>gi|38202237 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 40/101 (39%), Positives = 54/101 (53%), Gaps = 6/101 (5%)

Query: 45  NCAEAEEGGCR-GAPRKLRARRGGRSRP---KSELALSKQ--RRSRRKKANDRERNRMHN 98
           N +  E   C  G+P+K R   G R +    KS L+   Q  ++ +R  AN RER RM  
Sbjct: 35  NESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRV 94

Query: 99  LNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTL 139
           L+ A   L+  LP  P D KL+K++TLR A +YI  L Q L
Sbjct: 95  LSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQIL 135


>gi|38202239 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 40/101 (39%), Positives = 54/101 (53%), Gaps = 6/101 (5%)

Query: 45  NCAEAEEGGCR-GAPRKLRARRGGRSRP---KSELALSKQ--RRSRRKKANDRERNRMHN 98
           N +  E   C  G+P+K R   G R +    KS L+   Q  ++ +R  AN RER RM  
Sbjct: 35  NESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRV 94

Query: 99  LNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTL 139
           L+ A   L+  LP  P D KL+K++TLR A +YI  L Q L
Sbjct: 95  LSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQIL 135


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 35/76 (46%), Positives = 42/76 (55%), Gaps = 1/76 (1%)

Query: 80  QRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTL 139
           Q+ +RR   N RER R  N+N A   LR +LPT P D KL+K E LR A  YI  L + L
Sbjct: 147 QKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLL 206

Query: 140 RIADHSLYA-LEPPAP 154
           R    +L A   PP P
Sbjct: 207 RDQAAALAAGPTPPGP 222


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 11/162 (6%)

Query: 4   QPSGAPTVQVTRETERSFPRASEDEVTCPTSA--PPSPTR----TRGNCAEAEEGGCRGA 57
           +P   P + +     R  P A       P S   P  PTR    +  + +       + +
Sbjct: 147 EPGLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNNHQDS 206

Query: 58  PRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDA 117
               R R G  +   SE+   +Q  +RR  AN RER R+H +++A +ALR  +P +    
Sbjct: 207 SASPRKRPGEATAASSEIKALQQ--TRRLLANARERTRVHTISAAFEALRKQVPCYSYGQ 264

Query: 118 KLTKIETLRFAHNYIWALTQTLRI---ADHSLYALEPPAPHC 156
           KL+K+  LR A NYI +L +   +   ADHS  +       C
Sbjct: 265 KLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRC 306


>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
           sapiens]
          Length = 323

 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 31/57 (54%), Positives = 36/57 (63%), Gaps = 2/57 (3%)

Query: 85  RKKANDRERNRMHNLNSALDALRGVLPTF--PDDAKLTKIETLRFAHNYIWALTQTL 139
           R K N RER RMH+LN A+D LR V+P    P   KL+KI TL  A NYI  LT +L
Sbjct: 110 RLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSL 166


>gi|14149724 mesoderm posterior 1 [Homo sapiens]
          Length = 268

 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 45/113 (39%), Positives = 56/113 (49%), Gaps = 9/113 (7%)

Query: 56  GAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLP--TF 113
           G  R  RA   GR   +S    S QR+S    A++RE+ RM  L  AL  LR  LP    
Sbjct: 59  GTLRDPRAPSVGRRGARSSRLGSGQRQS----ASEREKLRMRTLARALHELRRFLPPSVA 114

Query: 114 PDDAKLTKIETLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGSPGGSP 166
           P    LTKIETLR A  YI  L+  L +++ S   L+      G+ GSP G P
Sbjct: 115 PAGQSLTKIETLRLAIRYIGHLSAVLGLSEES---LQRRCRQRGDAGSPRGCP 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,265,340
Number of Sequences: 37866
Number of extensions: 544658
Number of successful extensions: 2997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 2589
Number of HSP's gapped (non-prelim): 482
length of query: 214
length of database: 18,247,518
effective HSP length: 98
effective length of query: 116
effective length of database: 14,536,650
effective search space: 1686251400
effective search space used: 1686251400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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