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Search of human proteins with 6857826
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6857826 RNA-binding protein S1, serine-rich domain [Homo
sapiens]
(305 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapi... 603 e-173
gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sap... 603 e-173
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 591 e-169
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot... 591 e-169
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 589 e-168
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot... 589 e-168
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot... 589 e-168
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote... 589 e-168
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 90 2e-18
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 84 2e-16
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 83 3e-16
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 82 8e-16
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 81 1e-15
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 78 9e-15
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 76 3e-14
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 76 4e-14
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 76 4e-14
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 75 6e-14
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 74 1e-13
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 74 1e-13
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 74 1e-13
gi|9558733 transformer-2 alpha [Homo sapiens] 74 2e-13
gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens] 72 5e-13
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 71 1e-12
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 70 2e-12
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 69 4e-12
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 69 5e-12
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 69 5e-12
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 69 7e-12
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 69 7e-12
>gi|6857826 RNA-binding protein S1, serine-rich domain [Homo
sapiens]
Length = 305
Score = 603 bits (1555), Expect = e-173
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSSR
Sbjct: 301 SNSSR 305
>gi|18379334 RNA-binding protein S1, serine-rich domain [Homo
sapiens]
Length = 305
Score = 603 bits (1555), Expect = e-173
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSSR
Sbjct: 301 SNSSR 305
>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 6 [Homo sapiens]
Length = 305
Score = 591 bits (1523), Expect = e-169
Identities = 300/305 (98%), Positives = 301/305 (98%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYA VEFENPDEAEKALKHMDGGQIDGQEITAT VLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRP PRRFSPPRRMLPPPPMW RSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSS+
Sbjct: 301 SNSSQ 305
>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 2 [Homo sapiens]
Length = 305
Score = 591 bits (1523), Expect = e-169
Identities = 300/305 (98%), Positives = 301/305 (98%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYA VEFENPDEAEKALKHMDGGQIDGQEITAT VLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRP PRRFSPPRRMLPPPPMW RSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSS+
Sbjct: 301 SNSSQ 305
>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 589 bits (1518), Expect = e-168
Identities = 299/305 (98%), Positives = 300/305 (98%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKR SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYA VEFENPDEAEKALKHMDGGQIDGQEITAT VLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRP PRRFSPPRRMLPPPPMW RSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSS+
Sbjct: 301 SNSSQ 305
>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 589 bits (1518), Expect = e-168
Identities = 299/305 (98%), Positives = 300/305 (98%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKR SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYA VEFENPDEAEKALKHMDGGQIDGQEITAT VLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRP PRRFSPPRRMLPPPPMW RSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSS+
Sbjct: 301 SNSSQ 305
>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 589 bits (1518), Expect = e-168
Identities = 299/305 (98%), Positives = 300/305 (98%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKR SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYA VEFENPDEAEKALKHMDGGQIDGQEITAT VLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRP PRRFSPPRRMLPPPPMW RSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSS+
Sbjct: 301 SNSSQ 305
>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 3 [Homo sapiens]
Length = 305
Score = 589 bits (1518), Expect = e-168
Identities = 299/305 (98%), Positives = 300/305 (98%)
Query: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD
Sbjct: 1 MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 61 KTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
KTRKR SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI
Sbjct: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
FSTYGKIKMIDMPVERMHPHLSKGYA VEFENPDEAEKALKHMDGGQIDGQEITAT VLA
Sbjct: 181 FSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVVLA 240
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
PWPRP PRRFSPPRRMLPPPPMW RSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS
Sbjct: 241 PWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
Query: 301 SNSSR 305
SNSS+
Sbjct: 301 SNSSQ 305
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 90.1 bits (222), Expect = 2e-18
Identities = 61/121 (50%), Positives = 73/121 (60%), Gaps = 9/121 (7%)
Query: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
S K+K RS+ +G R R+KT K RS SS SSS+ S S+S+SS SS+S SS
Sbjct: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
Query: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
Query: 155 S 155
S
Sbjct: 663 S 663
Score = 78.6 bits (192), Expect = 7e-15
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 49 TKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
Query: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
Score = 62.4 bits (150), Expect = 5e-10
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
Query: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
Query: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
+ + + S + TK + +R+ K I E
Sbjct: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
Score = 58.9 bits (141), Expect = 5e-09
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
Query: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
Query: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
+ N R R +S K R E++RK
Sbjct: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
Score = 49.7 bits (117), Expect = 3e-06
Identities = 45/137 (32%), Positives = 58/137 (42%), Gaps = 8/137 (5%)
Query: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
Query: 64 KRRSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
R+ S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
Query: 119 SSSGSPSPSRRRHDNRR 135
S S S R+ D RR
Sbjct: 702 SRSERDRKSDRK-DKRR 717
Score = 47.0 bits (110), Expect = 2e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRRSASSGS 72
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
Query: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
Query: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
S S +R SRS+ + K D K+++R
Sbjct: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 83.6 bits (205), Expect = 2e-16
Identities = 55/145 (37%), Positives = 78/145 (53%), Gaps = 8/145 (5%)
Query: 161 TKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKAL 220
T + + LT + D + +F YG++ + +P +R + S+G+A+V F + +AE A+
Sbjct: 14 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDR-YTKESRGFAFVRFHDKRDAEDAM 72
Query: 221 KHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRR 280
MDG +DG+E+ +A + RPP S R PPP R RRSRSPRRR
Sbjct: 73 DAMDGAVLDGRELRVQ--MARYGRPPDSHHS---RRGPPPR--RYGGGGYGRRSRSPRRR 125
Query: 281 SPVRRRSRSPGRRRHRSRSSSNSSR 305
R RSRS R R RSR S + SR
Sbjct: 126 RRSRSRSRSRSRSRSRSRYSRSKSR 150
Score = 63.9 bits (154), Expect = 2e-10
Identities = 52/129 (40%), Positives = 66/129 (51%), Gaps = 13/129 (10%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSS 81
S R P P +R + RS + S + R R ++R R S S S TRSRS S
Sbjct: 101 SRRGPPP-RRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRS 159
Query: 82 TSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKS 141
TS S S+ + S SS+ SRS S S SRS S S P P +R +++ RSRSKS
Sbjct: 160 TSKSRSARRS-----KSKSSSVSRSRSRSRSRSRSRS-----PPPVSKR-ESKSRSRSKS 208
Query: 142 KPPKRDEKE 150
PPK E+E
Sbjct: 209 -PPKSPEEE 216
Score = 61.2 bits (147), Expect = 1e-09
Identities = 46/105 (43%), Positives = 53/105 (50%), Gaps = 13/105 (12%)
Query: 57 RGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSS 116
R R R+RRS S S +RSRS S S S S SRS S+S SRS+
Sbjct: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSR----------TRSRSRSTSKSRSAR 167
Query: 117 SSSSSGSPSPSRRRHDNRRRSRSKSKPP--KRDEKERKRRSPSPK 159
S S S S SR R +R RSRS+S PP KR+ K R R PK
Sbjct: 168 RSKSKSS-SVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPK 211
Score = 49.7 bits (117), Expect = 3e-06
Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 10/105 (9%)
Query: 24 RAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR---------RSASSGSSS 74
R+ SP +R+ RS +S+ RS+ + ++ S K R R ++R R RS S SS
Sbjct: 118 RSRSPRRRR-RSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSS 119
+RSRS S S S S + S S S + S+S S + SS
Sbjct: 177 SRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221
Score = 37.0 bits (84), Expect = 0.022
Identities = 27/66 (40%), Positives = 32/66 (48%)
Query: 92 GSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKER 151
G S S RS S S SRS S S S S S SR R +R RS SKS+ +R + +
Sbjct: 114 GYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKS 173
Query: 152 KRRSPS 157
S S
Sbjct: 174 SSVSRS 179
Score = 37.0 bits (84), Expect = 0.022
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 3/88 (3%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRR 66
+ +S + +S TR+ S + K RS +SK +S + S + R R ++R
Sbjct: 137 RSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKS---SSVSRSRSRSRSRSRSRSPP 193
Query: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSS 94
S S +RSRS S S SS
Sbjct: 194 PVSKRESKSRSRSKSPPKSPEEEGAVSS 221
Score = 28.5 bits (62), Expect = 7.7
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 5/67 (7%)
Query: 105 RSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164
RS S R S S S S S S SR R+ SRSKS+ R +S S + +K
Sbjct: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRY-----SRSKSRSRTRSRSRSTSKSRSARRSKSK 172
Query: 165 IGRLTRN 171
++R+
Sbjct: 173 SSSVSRS 179
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 83.2 bits (204), Expect = 3e-16
Identities = 69/222 (31%), Positives = 104/222 (46%), Gaps = 32/222 (14%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSS 81
+TR P K RS + + + + + RGR+ RS SSGS+ T SSS
Sbjct: 1388 NTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNS----RSVSSGSNRTSEASSS 1443
Query: 82 TSSSGSST--------------------STGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
+SSS SS+ S+G S SSSS+SS S SSS+S SSSS S S
Sbjct: 1444 SSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRS 1503
Query: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIF 181
SPSP RR RR S +S + ++ ++ + V IG++ +T+ + + F
Sbjct: 1504 RSPSPRRRSDRRRRYSSYRSHDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELKQRF 1563
Query: 182 STYGKIK--MIDMPVERMHPHLSKGYAYVEFENPDEAEKALK 221
S +G+I+ I V+ Y +V + +EA A++
Sbjct: 1564 SVFGEIEECTIHFRVQ------GDNYGFVTYRYAEEAFAAIE 1599
Score = 29.6 bits (65), Expect = 3.5
Identities = 24/68 (35%), Positives = 25/68 (36%), Gaps = 14/68 (20%)
Query: 251 SPPRRMLPPPPMWRRSPPRMRRRSR--------------SPRRRSPVRRRSRSPGRRRHR 296
S R + PP WRRS RSR S S R RSRSP RR
Sbjct: 1453 SRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRS 1512
Query: 297 SRSSSNSS 304
R SS
Sbjct: 1513 DRRRRYSS 1520
Score = 28.5 bits (62), Expect = 7.7
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 266 SPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSR 298
S R R RS SPRRRS RRR S H R
Sbjct: 1497 SSSRSRSRSPSPRRRSDRRRRYSSYRSHDHYQR 1529
>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
Length = 288
Score = 81.6 bits (200), Expect = 8e-16
Identities = 63/194 (32%), Positives = 91/194 (46%), Gaps = 19/194 (9%)
Query: 71 GSSSTRSRSSSTSSSGSSTS---TGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPS 127
G +RS S S S+ GS S T + S S S SRS S S S S S S S +
Sbjct: 10 GERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYT 69
Query: 128 RRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPT-KVHIGR--------------LTRNV 172
R R +R RS+S+ RD + R S SP T + H+G L+
Sbjct: 70 RSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYT 129
Query: 173 TKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQE 232
T+ + E+FS YG I + + V S+G+A+V FEN D+A++A + +G ++DG+
Sbjct: 130 TERDLREVFSKYGPIADVSI-VYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRR 188
Query: 233 ITATAVLAPWPRPP 246
I + P P
Sbjct: 189 IRVDFSITKRPHTP 202
Score = 34.7 bits (78), Expect = 0.11
Identities = 26/61 (42%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
Query: 249 RFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSP----VRRRSRSPGRRRHRSRSSSNSS 304
R +P R RS R R SRS RRS R RSRS RR RSRS S
Sbjct: 31 RHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSYSRDY 90
Query: 305 R 305
R
Sbjct: 91 R 91
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 81.3 bits (199), Expect = 1e-15
Identities = 92/307 (29%), Positives = 116/307 (37%), Gaps = 52/307 (16%)
Query: 2 DLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRG--- 58
D + K L + K R+P+ K K KSKDR K ES +DRG
Sbjct: 234 DQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSP-IINESRSRDRGKKS 292
Query: 59 ------RDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTS 112
R K++ RRS S S RS + S S +SSG + S S R G S
Sbjct: 293 RSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKR 352
Query: 113 RSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNV 172
RS SP P D RRSRS P D + ++ +SPS
Sbjct: 353 RSL-------SPKP----RDKSRRSRS---PLLNDRRSKQSKSPS--------------- 383
Query: 173 TKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQE 232
S + K + +R P + + D + + D I+
Sbjct: 384 ------RTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWS 437
Query: 233 ITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGR 292
T +P R R SP RR P RR RRR R R RS +RRRSRS G
Sbjct: 438 PTRRRSRSPIRR---RSRSPLRRSRSP----RRRSRSPRRRDRGRRSRSRLRRRSRSRGG 490
Query: 293 RRHRSRS 299
RR RSRS
Sbjct: 491 RRRRSRS 497
Score = 66.2 bits (160), Expect = 3e-11
Identities = 90/322 (27%), Positives = 128/322 (39%), Gaps = 50/322 (15%)
Query: 18 NKKSSTRAPSPTKRKDRSDEKSKDRSKDKGA-------TKESSEKDRGRDKTRKRRSAS- 69
+ K +T+ S ++ K+R+ +S D+ K KG T S K+R + K+ +RS S
Sbjct: 175 DNKITTKKRSKSRSKERTRHRS-DKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQ 233
Query: 70 -----SGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP 124
S S + R RS S + S + R S + S S S
Sbjct: 234 DQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSR 293
Query: 125 SPSRRRHDNR-RRSRSKSKPPKRDEKERKRRSPSPKPTK-VHIGRLTRNVTKDHIMEIFS 182
SP R ++ RRSRSK + KR E +++++ P P+K G+ R+ ++
Sbjct: 294 SPVDLRGKSKDRRSRSKERKSKRSETDKEKK-PIKSPSKDASSGKENRSPSRRPGRSPKR 352
Query: 183 TYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPW 242
K D P L+ D K K G+ + ++
Sbjct: 353 RSLSPKPRDKSRRSRSPLLN-----------DRRSKQSKSPSRTLSPGRRAKSRSLERKR 401
Query: 243 PRPPPRRFSPPR------------RMLPPPPMWRRSPPRMRRRSRSP---RRRSPVRRRS 287
P RR S PR R P+ R SP R RRSRSP R RSP+RR S
Sbjct: 402 REPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTR--RRSRSPIRRRSRSPLRR-S 458
Query: 288 RSPGRR----RHRSRSSSNSSR 305
RSP RR R R R + SR
Sbjct: 459 RSPRRRSRSPRRRDRGRRSRSR 480
Score = 60.1 bits (144), Expect = 2e-09
Identities = 73/281 (25%), Positives = 108/281 (38%), Gaps = 37/281 (13%)
Query: 46 KGATKESSEKDRGRDKTRKRRSASSGSSSTRSR---------SSSTSSSGSSTSTGSSSG 96
+G S E+ +K R +S+ SSST+ + + S S S T S
Sbjct: 138 QGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSD 197
Query: 97 SSSSSASSRSGSSSTSRSSSSS-SSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRS 155
S T+RS S S SPS + D R+S+S + + EK K RS
Sbjct: 198 KKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARS 257
Query: 156 PSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFEN--- 212
P+ K+ +++ K I+ + + K PV+ + E ++
Sbjct: 258 PTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRS 317
Query: 213 -PDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRR--FSPPRRMLPPPPMWRRSPPR 269
D+ +K +K G+E R P RR SP RR L P P +
Sbjct: 318 ETDKEKKPIKSPSKDASSGKE----------NRSPSRRPGRSPKRRSLSPKPRDK----- 362
Query: 270 MRRRSRSPRRRSPVRRRSRSPGR-----RRHRSRSSSNSSR 305
RRSRSP ++S+SP R RR +SRS R
Sbjct: 363 -SRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRR 402
Score = 45.4 bits (106), Expect = 6e-05
Identities = 42/132 (31%), Positives = 54/132 (40%), Gaps = 4/132 (3%)
Query: 15 KENNKKSSTRAPSPTKR-KDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSS 73
+ KS +R SP +R K RS E+ + ++ + SS + R RD RR S +S
Sbjct: 375 RSKQSKSPSRTLSPGRRAKSRSLERKR---REPERRRLSSPRTRPRDDILSRRERSKDAS 431
Query: 74 STRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDN 133
S + S S S S S + R S R S S SR R
Sbjct: 432 PINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGR 491
Query: 134 RRRSRSKSKPPK 145
RRRSRSK K K
Sbjct: 492 RRRSRSKVKEDK 503
Score = 35.8 bits (81), Expect = 0.048
Identities = 40/173 (23%), Positives = 61/173 (35%), Gaps = 4/173 (2%)
Query: 8 KKSLLGVKENNKKSST-RAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRR 66
+ +L +E +K +S SPT+R+ RS + + RS + + R + R RR
Sbjct: 417 RDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRR 476
Query: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
S S +RSR S S GS S SSS +
Sbjct: 477 SRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSS---DDNLEDFDVEEED 533
Query: 127 SRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
+ RR R + E S +P+ TR+ + D I+E
Sbjct: 534 EEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDILE 586
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 78.2 bits (191), Expect = 9e-15
Identities = 61/147 (41%), Positives = 79/147 (53%), Gaps = 5/147 (3%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRS-KDKGATKESSEKDRGRDKTRKRRSASSGSSSTRS 77
K+++T P + + D + +S K K S + R R KT +++S SS + S
Sbjct: 500 KEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSS 559
Query: 78 RSSSTSSSGSSTSTG-SSSGSSSSSASSRSGSSSTSRSSSSS-SSSGSPSPSRRRHDNRR 135
RSSS S SGSS S SSS SS SS SSR S S SRS S S SSS SPSP+ H
Sbjct: 560 RSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSI 619
Query: 136 RSRSKSKPP--KRDEKERKRRSPSPKP 160
R++ + PP K EK K+ +P P P
Sbjct: 620 RTKGEPAPPPGKAGEKSVKKPAPPPAP 646
Score = 59.7 bits (143), Expect = 3e-09
Identities = 51/159 (32%), Positives = 77/159 (48%), Gaps = 17/159 (10%)
Query: 6 VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65
VKK + K++ P PTK D + + K+R + R +T
Sbjct: 637 VKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPA----------RTPPRRRTLSG 686
Query: 66 RSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSS--SSSSSGS 123
+ SGSS + S S S S S SS S+ SS+ SSSSSA S + +S SS+SS S
Sbjct: 687 SGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRS 746
Query: 124 PSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
P+P++ R+ + KSK ++E+++R S +P K
Sbjct: 747 PAPAQ-----TRKEKGKSKKEDGVKEEKRKRDSSTQPPK 780
Score = 56.6 bits (135), Expect = 3e-08
Identities = 51/155 (32%), Positives = 70/155 (45%), Gaps = 32/155 (20%)
Query: 31 RKDRSDEKSKDRSKDKGATKESSEKDRGRD-KTRKRRSASSGSSSTR------------- 76
R+ R ++ K+R K+KG K S + R + K+ +A++G R
Sbjct: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKS 524
Query: 77 -------SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS---SSTSRSSSSSSSSGSPSP 126
S S S + TS S+S S+SS +SSRS S S +SRS S SSS S S
Sbjct: 525 PKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSS 584
Query: 127 SRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPT 161
RH + SRS+S+ SPSP PT
Sbjct: 585 RSSRHSSFSGSRSRSR--------SFSSSPSPSPT 611
Score = 41.6 bits (96), Expect = 9e-04
Identities = 52/303 (17%), Positives = 97/303 (32%), Gaps = 18/303 (5%)
Query: 17 NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR 76
N ++ ++++R E+ +DR +++ + E++ RDK R+RR R
Sbjct: 400 NYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEE--WERER 457
Query: 77 SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRR 136
++ RS + ++ + + P +R D +
Sbjct: 458 AKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKD 517
Query: 137 SRSKSKPPKR--------DEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIK 188
+SK PK+ R+R++ + + + R + + + +
Sbjct: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSS 577
Query: 189 MIDMPVERMHPHL----SKGYAYVEFENPDEAEKALKHMDGGQIDGQEI----TATAVLA 240
R H S+ + +P + H + G+ A
Sbjct: 578 SYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSV 637
Query: 241 PWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
P PPP + P P + PR RR P R P RR G S S
Sbjct: 638 KKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSG 697
Query: 301 SNS 303
S+S
Sbjct: 698 SSS 700
Score = 38.1 bits (87), Expect = 0.010
Identities = 31/165 (18%), Positives = 62/165 (37%), Gaps = 16/165 (9%)
Query: 21 SSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80
+S+R+P+P + + K K +SK + KE K + K +G S++ S+
Sbjct: 742 ASSRSPAPAQTR-----KEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPST 796
Query: 81 STSSSGSSTSTGSS-----------SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRR 129
+ G+ + ++ + R S R S + + SP R
Sbjct: 797 PQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRG 856
Query: 130 RHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174
D + R S P+R + + +P K + +++ +K
Sbjct: 857 SRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSK 901
Score = 33.9 bits (76), Expect = 0.18
Identities = 53/304 (17%), Positives = 99/304 (32%), Gaps = 34/304 (11%)
Query: 29 TKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSS 88
T+ + + + ++R +++ + E++R RD+ R+RR R
Sbjct: 393 TETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEE 452
Query: 89 TSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKP--PKR 146
+ SP P R+ + ++ + + P +
Sbjct: 453 WERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRA 512
Query: 147 DE-KERKRRSPSPK-----PTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPH 200
DE K+ RRS SPK R R + S+ +
Sbjct: 513 DEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRS 572
Query: 201 LSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPP 260
S+ +Y + + ++ +H + + ++ +P P P P R S + P P
Sbjct: 573 RSRSSSYSSY-----SSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAP 627
Query: 261 PMWRR------------SPPRMRR---------RSRSPRRRSPVRRRSRSPGRRRHRSRS 299
P + +PP+ + + PR R +R+P RRR S S
Sbjct: 628 PPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGS 687
Query: 300 SSNS 303
S S
Sbjct: 688 GSGS 691
Score = 32.3 bits (72), Expect = 0.54
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 32 KDRSDEKSKDRSKDKGATKESSEKDRG-RDKTRKRRSASSGSSSTRSRSSSTSSSGSSTS 90
+ R + KDR A + ++ DRG RD+ R S R ++S ++ +
Sbjct: 830 RKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRK 889
Query: 91 TGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHD 132
S S SSS + S S ++S+ SG S RR +
Sbjct: 890 RQLSPQSKSSSKVT-SVPGKASDPGAASTKSGKASTLSRREE 930
Score = 32.0 bits (71), Expect = 0.70
Identities = 47/206 (22%), Positives = 71/206 (34%), Gaps = 55/206 (26%)
Query: 131 HDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMI 190
H+ R R R + + ++ E+ER+R + + + R ++H
Sbjct: 399 HNYRERERERERENRQRERERERERDRERERR----QREREREREH-------------- 440
Query: 191 DMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRF 250
ER + + E E EK +H D + +E P+PP R+
Sbjct: 441 ----ERDKERQRRKEEW-ERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQA 495
Query: 251 SPPRRMLPPP-----------PMWRRS------------PPRMRRRSRSPRRRSPVRRRS 287
PP++ WRRS P R RRR ++ + S
Sbjct: 496 EPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSS 555
Query: 288 RS---------PGRRRHRSRSSSNSS 304
RS G R RSRSSS SS
Sbjct: 556 RSSSRSSSYSGSGSSRSRSRSSSYSS 581
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 76.3 bits (186), Expect = 3e-14
Identities = 55/159 (34%), Positives = 72/159 (45%), Gaps = 12/159 (7%)
Query: 10 SLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR---- 65
+L KE SS+ + S + S S S + E S + KR
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582
Query: 66 --------RSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117
R + R +SSS SS+S+ SSS SSSSS+SS S SSS+S SSSS
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Query: 118 SSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSP 156
SSSS SPSP++ + S KPP + + R R P
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Score = 73.9 bits (180), Expect = 2e-13
Identities = 54/124 (43%), Positives = 70/124 (56%), Gaps = 12/124 (9%)
Query: 48 ATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG 107
A KE+ + R + T +R S SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-SS 2643
Query: 108 SSSTSRSSSSSSSSGSPSPS--RRRHDNRRRSRSKSKP--PKRDEK-------ERKRRSP 156
SSS+S S + P P+ ++ RRSRS KP RD + ER+R SP
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
Query: 157 SPKP 160
P P
Sbjct: 2704 QPSP 2707
Score = 73.2 bits (178), Expect = 3e-13
Identities = 82/306 (26%), Positives = 119/306 (38%), Gaps = 36/306 (11%)
Query: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRS-DEKSKDRS--KDKGATKESSEKD-RGRDKTR 63
++S G + + +P D S D K+K R+ + + + S E D + R R
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
Query: 64 KRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSS-SASSRSGSSSTSRSSS---SSS 119
+ RS SS + R++ + SGS +S + + + SRSGSSS R S SSS
Sbjct: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
+ SP + RR SRS +P + +RRS P RL+R
Sbjct: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRR------SR 1708
Query: 180 IFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVL 239
S+ + + P R P +S +P+ AEK+ T+
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVS---------SPEPAEKSRSSRRRRSASSPRTKTTSRR 1759
Query: 240 APWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRS 299
P P PR +RS R RR RR S+S RRR RSRS
Sbjct: 1760 GRSPSPKPRGL-------------QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
Query: 300 SSNSSR 305
S +R
Sbjct: 1807 RSRVTR 1812
Score = 72.0 bits (175), Expect = 6e-13
Identities = 89/306 (29%), Positives = 124/306 (40%), Gaps = 34/306 (11%)
Query: 19 KKSSTRAPSPTKRKDRSDEK-------SKDRSKDKGATKESSEKDRGRDKTRK-RRSASS 70
++ +R+ +P +R RS + S+ R+ +G ++ S RGR +R +R S
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
Query: 71 GSSSTRSRSSSTSSSGS-STSTGSSSGSSSSSASSRSGSSSTSRSSSSSS-----SSGSP 124
GSSS R S TS S S S+ S SS SRS SS S++ S S S SP
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 125 SPSRRRHDNRRRSRSKSKPPKRDEKERKRR-----SPSPKPTKVHIGRLTRNVTKDHIME 179
P ++ RRSRS S PK + RR SP PK R + + + H
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKV 844
Query: 180 IFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKA---LKHMDGGQIDGQEITAT 236
T + I P + + E +PD K+ +H G + ++T
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFE-SSPDPELKSRTPSRHSCSGSSPPRVKSST 903
Query: 237 AVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHR 296
PPR+ SP R P P + PR R S S SP R SR+ RR
Sbjct: 904 ---------PPRQ-SPSRSSSPQPKVKAIISPRQRSHSGS-SSPSPSRVTSRTTPRRSRS 952
Query: 297 SRSSSN 302
SN
Sbjct: 953 VSPCSN 958
Score = 67.8 bits (164), Expect = 1e-11
Identities = 87/316 (27%), Positives = 130/316 (41%), Gaps = 46/316 (14%)
Query: 15 KENNKKSSTRAPSPTK-RKDRSDE-KSKDRSKDKGATKESSEKDRGRDKTRKRR-SASSG 71
K+++KK R+ S +K RK RS KSK +SKDK + S + + R SA S
Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
Query: 72 SSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG----------SSSTSRSSSSSSSS 121
SSS SRS S S++ + T T + +G S S AS R G ++ST R SS +++
Sbjct: 270 SSSDTSRSRSRSAA-AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT 328
Query: 122 GSPSPSRRRHDNRRRSRSKSKP---PKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIM 178
PS D ++ +S ++P P+R + +P+P + H G T
Sbjct: 329 KQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQ 388
Query: 179 EIFSTYGKIKMI-DMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATA 237
E + + D + L + + + K +H +++
Sbjct: 389 EPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRH-----------ASSS 437
Query: 238 VLAPWPRPPPRRFSPPRRMLPPPPMWRRS-------------PPRMRRRSRSPRRRSPVR 284
+P P P P R + P RS P R RSRSP R
Sbjct: 438 PESPKPAPAP---GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR 494
Query: 285 RRSRSPGRRRH-RSRS 299
RSR+P +R H RSRS
Sbjct: 495 SRSRTPTKRGHSRSRS 510
Score = 67.0 bits (162), Expect = 2e-11
Identities = 85/322 (26%), Positives = 126/322 (39%), Gaps = 44/322 (13%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR- 65
KKK E++ R S K+K RS+ +SK R K + T +S K + DK RKR
Sbjct: 192 KKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR-KHRSPTPKSKRKSK--DKKRKRS 248
Query: 66 ---------------RSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSS 110
SA S SSS SRS S S++ + T T + +G S S AS R G
Sbjct: 249 RSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA-AKTHTTALAGRSPSPASGRRGEGD 307
Query: 111 TSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTR 170
S ++S+ PS ++ S + +D+KE+ PSP P + G
Sbjct: 308 APFSEPGTTSTQRPSSPETA---TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPP 364
Query: 171 NVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDG 230
T + + + E ++P P EA +
Sbjct: 365 APTPLLAERHGGSPQPLATTPLSQEPVNP-------------PSEASPTRDRSPPKSPEK 411
Query: 231 QEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSP--RRRSPVRRR-- 286
++++ +P P P P + S P P +P R S SP + RS R +
Sbjct: 412 LPQSSSSESSP-PSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRD 470
Query: 287 ---SRSPGRRRHRSRSSSNSSR 305
S +P RR RSRS + + R
Sbjct: 471 KSHSHTPSRRMGRSRSPATAKR 492
Score = 67.0 bits (162), Expect = 2e-11
Identities = 83/300 (27%), Positives = 119/300 (39%), Gaps = 27/300 (9%)
Query: 24 RAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTS 83
R+PS + + +S R + + + + RGR + K R S +RSR T
Sbjct: 1726 RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR--SRSRSRREKTR 1783
Query: 84 SSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS---SSSGSPSPSRRRHDNRRRSRSK 140
++ +GSS +S SRS S T R S S S + S R RRR RS+
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
Query: 141 SKPPKRDEKERKRRSPSP-KPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHP 199
+ P R ++ R R SP+P K ++ T ++ I + + + R
Sbjct: 1844 TPPTSR-KRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902
Query: 200 HLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPP----RR 255
S + A + + + P R R +PP R
Sbjct: 1903 RTS----VTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRS 1958
Query: 256 MLPPPPMWR-----RSPPRMRRRSRSPRRRSPV-RRRSRS----PGRRRHRSRSSSNSSR 305
PP+ R R+ P RRRSRS R SPV RRRSRS RRR RSR+S + R
Sbjct: 1959 RSRTPPVTRRRSRSRTSPITRRRSRS--RTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR 2016
Score = 65.9 bits (159), Expect = 4e-11
Identities = 75/306 (24%), Positives = 125/306 (40%), Gaps = 71/306 (23%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT-------------RKR 65
++ +R+ +P +R+ RS ++ RS+ ++ + + R R +T R+
Sbjct: 580 RRGRSRSRTPARRRSRSRTPTRRRSR----SRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
Query: 66 RSASSGSSSTRSRSSSTSSSGSSTS-TGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP 124
RS S S RSRS + + G S S T + G S S +R S SR+ + S S
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
Query: 125 SPSRRRHDNR---RRSRSKSKPPKR-----DEKERKRRSPSPKPTKVHIGRLTRNVTKDH 176
+P R R +R RR RS S+ P+R ERK +S + + R +R+ +
Sbjct: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ-------RRSRSNSSPE 748
Query: 177 IMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITAT 236
+ + + + + + P + LS + + G
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLS----------------LRRSLSGSS--------- 783
Query: 237 AVLAPWPRPPPRRFSPPRRM---LPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRR 293
P P + +PPRR P R+PPR R S SP P +++S++P R+
Sbjct: 784 ------PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP----PPKQKSKTPSRQ 833
Query: 294 RHRSRS 299
H S S
Sbjct: 834 SHSSSS 839
Score = 64.7 bits (156), Expect = 1e-10
Identities = 78/303 (25%), Positives = 126/303 (41%), Gaps = 25/303 (8%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGA----TKESSEKDRGRDKTRKRRSASSGSSSTRS 77
S + S ++R+ RS +S+ + +G ++ + ++ R +R+RR S ++R
Sbjct: 1791 SGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRK 1850
Query: 78 RSSSTSS--------SGSSTSTGSSSGSSSSSASSRSGSSSTS-----RSSSSSSSSGSP 124
RS S +S S +S +T S S + S R S TS RS S +S +
Sbjct: 1851 RSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR 1910
Query: 125 SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTY 184
S SR +RRRSRS++ PP + R R + + ++ +TR ++ + T
Sbjct: 1911 SRSRASPVSRRRSRSRT-PPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV--TR 1967
Query: 185 GKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPR 244
+ + P+ R S+ + + + +T + P
Sbjct: 1968 RRSRSRTSPITRRRSR-SRTSPVTRRRSRSRTSPVTRRRSRSRT--SPVTRRRSRSRTPP 2024
Query: 245 PPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRS--PRRRSPVRRRSRSPGRRRHRSRSSSN 302
RR +LP RSP +RRRSRS PR R +RSP R RS S S+
Sbjct: 2025 AIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS 2084
Query: 303 SSR 305
S R
Sbjct: 2085 SDR 2087
Score = 59.3 bits (142), Expect = 4e-09
Identities = 70/252 (27%), Positives = 93/252 (36%), Gaps = 56/252 (22%)
Query: 68 ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPS 127
AS+G+ + ++ + +S+ SSS SSSSS+SS S SSS+S SSSS S GS P
Sbjct: 2511 ASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570
Query: 128 RRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKI 187
+ R S P E R+ R P P P K R R+ + S+
Sbjct: 2571 Q---PEVALKRVPSPTPAPKEAVREGRPPEPTPAK----RKRRSSSSSSSSSSSSSSSSS 2623
Query: 188 KMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPP 247
S + +P A+ P P+ P
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSPSPAK-----------------------PGPQALP 2660
Query: 248 RRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRR------------RSPVRRR--SRSPGRR 293
+ SP + PP RRSRSPR+ SPV RR S P R
Sbjct: 2661 KPASP------------KKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
Query: 294 RHRSRSSSNSSR 305
+S SS SR
Sbjct: 2709 DQQSSSSERGSR 2720
Score = 58.9 bits (141), Expect = 5e-09
Identities = 91/309 (29%), Positives = 121/309 (39%), Gaps = 30/309 (9%)
Query: 20 KSSTRAPSPTKRKDRSDEK--SKDRSKDKGATKESSEKDRGRDKTRKRRS--ASSGSSST 75
K+ +R P P +R RS + K R + + SS + R R R RRS SS +
Sbjct: 1679 KTKSRTP-PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737
Query: 76 RSRSSSTSSSGSS--TSTGSSSGSSSSS-------ASSRSGSSSTSRSSSSSSSSGSPSP 126
+SRSS S SS T T S G S S + SRS T + S S S
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQST 1797
Query: 127 SRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGK 186
SRRR R RSRS+ +R RSP+ + + R R + +
Sbjct: 1798 SRRRQ--RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG--RSRTPPTSRKRSR 1853
Query: 187 IKMIDMPVERMHPHLSKG-YAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRP 245
+ P +R S + P + + + + + T+V R
Sbjct: 1854 SRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS 1913
Query: 246 PPRRFSPPRRMLPPPPMWRR----SPPRMRRRSRSPRRRSPV-RRRSRS----PGRRRHR 296
S R PP+ RR P RRRSRS R PV RRRSRS RRR R
Sbjct: 1914 RASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS--RTPPVTRRRSRSRTPPVTRRRSR 1971
Query: 297 SRSSSNSSR 305
SR+S + R
Sbjct: 1972 SRTSPITRR 1980
Score = 57.0 bits (136), Expect = 2e-08
Identities = 77/296 (26%), Positives = 107/296 (36%), Gaps = 67/296 (22%)
Query: 27 SPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSG 86
SPT+ DRS KS ++ +++ S + +R S+ + S S
Sbjct: 398 SPTR--DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISS 455
Query: 87 SSTSTGSSSG-----SSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRR-----R 136
S TS S G S S SR S S +++ S S +P++R H R R
Sbjct: 456 SPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRR 515
Query: 137 SRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVER 196
SRS + + +R+ RS SP+
Sbjct: 516 SRSAQRWGRSRSPQRRGRSRSPQ------------------------------------- 538
Query: 197 MHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRM 256
P S+ A + H G+ + T P R R +P RR
Sbjct: 539 -RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRT----PARRGRSRSRTPARRR 593
Query: 257 LPPPPMWRRSPPRMRRRSRSP------RRRSPVRRRS--RSPGRRRHRSRSSSNSS 304
R+P R R RSR+P R R+P RRRS RSP RRR RSRS + S
Sbjct: 594 -----SRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS 644
Score = 55.1 bits (131), Expect = 8e-08
Identities = 80/298 (26%), Positives = 118/298 (39%), Gaps = 29/298 (9%)
Query: 15 KENNKKSSTRAPSPTK--RKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGS 72
+ ++ +SS +P PTK R S +S + G+ +E S ++++ R
Sbjct: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSH 473
Query: 73 SSTRSRSSSTSSSGSSTSTGSS-SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRH 131
S T SR S S ++ G S S + + SRS S RS S+ S SP RR
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG- 532
Query: 132 DNRRRSRSKSKP--PKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKM 189
RSRS +P + +R+ RS S + + H +R+ +T G+ +
Sbjct: 533 ----RSRSPQRPGWSRSRNTQRRGRSRSARRGRSH----SRSP---------ATRGRSRS 575
Query: 190 IDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRR 249
P R S+ A + + + + A R P RR
Sbjct: 576 -RTPARRGRSR-SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRR 633
Query: 250 FSPPRRMLPPPPMWRRSPP--RMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR 305
S R R P R R RSR+P RR R RSR+P RR RSRS + + R
Sbjct: 634 RSRSRSPARRSGRSRSRTPARRGRSRSRTPARRG--RSRSRTPARRSGRSRSRTPARR 689
Score = 54.7 bits (130), Expect = 1e-07
Identities = 51/171 (29%), Positives = 68/171 (39%), Gaps = 35/171 (20%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSS 74
KE ++ P+P KRK RS S S ++ SS S+SS SSS
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS---------SSSSSSSS 2637
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS------SSSSSSSGSPSPSR 128
+ S SSS+SSS S G + +S SRS S S S S SP
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE 2697
Query: 129 RR-----------------HDNRRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
RR +RR R S+ P +R+R +PSP+P +
Sbjct: 2698 RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSH---KRRRETPSPRPMR 2745
Score = 54.3 bits (129), Expect = 1e-07
Identities = 77/312 (24%), Positives = 109/312 (34%), Gaps = 34/312 (10%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGR--DKTRKRRSASSGSSSTR 76
+++ AP P K E S RS K+ +KDRGR + + RR S +
Sbjct: 158 REAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217
Query: 77 SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRR 136
RS S S S S S R S ST+ + S + S S + R
Sbjct: 218 HRSESESKKRKHRSPTPKS-KRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR 276
Query: 137 SRSKSKPPKRDEKERKRRSPSPKPTKVHIGRL------TRNVTKDHIMEIFSTYGKIKMI 190
SRS+S K RSPSP + G T + + E +
Sbjct: 277 SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336
Query: 191 DMPVERMHPHLSKGYAYVEFEN----PDEAEKALKHMDGGQIDGQEITATAVLAPWPRPP 246
D ++ ++ E + P L GG + AT L+ P P
Sbjct: 337 DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGG---SPQPLATTPLSQEPVNP 393
Query: 247 PRRFSPPRRMLPPPPMWRRSPPRMRRRSR------SPRRRSPVRRRSRSPGRRR------ 294
P SP R PP +SP ++ + S SP+ R S SP +
Sbjct: 394 PSEASPTRDRSPP-----KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPG 448
Query: 295 -HRSRSSSNSSR 305
HR SSS +S+
Sbjct: 449 SHREISSSPTSK 460
Score = 51.6 bits (122), Expect = 9e-07
Identities = 86/310 (27%), Positives = 118/310 (38%), Gaps = 62/310 (20%)
Query: 20 KSSTRAPSPTKRKDRSDEKSK-DRSKDKGATKESSEKDRGRDKTRKR---RSASSGSSST 75
KS + PS + RS +K RS+ + TK + R R R R S S
Sbjct: 471 KSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR 530
Query: 76 RSRSSSTSSSGSSTSTGSSS-GSSSSSASSRSGSSST-------SRSSSSSSSSGSPSPS 127
R RS S G S S + G S S+ RS S S SR+ + S S +P+
Sbjct: 531 RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPA 590
Query: 128 RRRHDNRR--RSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYG 185
RRR +R R RS+S+ P R + R R+P+ + ++ TR+
Sbjct: 591 RRRSRSRTPTRRRSRSRTPARRGRSRS-RTPARRRSR------TRS-------------- 629
Query: 186 KIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRP 245
PV R S + A + G+ + T
Sbjct: 630 -------PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRT--------- 673
Query: 246 PPRRFSPPRRMLPPPPMWR---RSPPRMRRRSRSPRR------RSPVRR-RSRSPGRRRH 295
P R S R P R R+P R R RSRS R R+P RR RS S R++
Sbjct: 674 -PARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKN 732
Query: 296 RSRSSSNSSR 305
+SR+S SR
Sbjct: 733 KSRTSQRRSR 742
Score = 51.6 bits (122), Expect = 9e-07
Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 11/144 (7%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSR 78
K+S +RA T R+ RS R + + T S + R R +T R S +S SR
Sbjct: 1862 KRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR-RSRSRTSVTRRRSRSRASPVSR 1920
Query: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNR---- 134
S S + T S S + ++ SRS + +R S S + P +RRR +R
Sbjct: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT---PPVTRRRSRSRTSPI 1977
Query: 135 --RRSRSKSKPPKRDEKERKRRSP 156
RRSRS++ P R + R R SP
Sbjct: 1978 TRRRSRSRTSPVTR-RRSRSRTSP 2000
Score = 51.6 bits (122), Expect = 9e-07
Identities = 46/152 (30%), Positives = 66/152 (43%), Gaps = 13/152 (8%)
Query: 18 NKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKE-SSEKDRGRDKTRKRRSASSGSSSTR 76
+++ S S T+R+ RS R + + T + + R R T +RRS S TR
Sbjct: 1896 SRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTR 1955
Query: 77 SRSSS--------TSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSR 128
RS S S S +S T S S +S + R S TS + S S + +R
Sbjct: 1956 RRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTR 2015
Query: 129 RRHDNRR----RSRSKSKPPKRDEKERKRRSP 156
RR +R R RS+S+ P K + RSP
Sbjct: 2016 RRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSP 2047
Score = 51.6 bits (122), Expect = 9e-07
Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 13/163 (7%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDK-TRKR 65
+++S ++S +RA ++R+ RS R + + T + + R R +R
Sbjct: 1897 RRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRR 1956
Query: 66 RSASSGSSSTRSRSSSTSS--------SGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117
RS S TR RS S +S S +S T S S +S + R S TS +
Sbjct: 1957 RSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR 2016
Query: 118 SSSSGSPSPSRRRHDNRR----RSRSKSKPPKRDEKERKRRSP 156
S S +P RRR +R R RS+S+ P + + R+P
Sbjct: 2017 RSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 15/154 (9%)
Query: 18 NKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGR-DKTRKRRSASSGSSSTR 76
+++S +R P ++R+ RS R + + T + + R R +RRS S TR
Sbjct: 1873 HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
Query: 77 SRSSST-------SSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRR 129
RS S S S + T S S + + R S TS + S S + +RR
Sbjct: 1933 RRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRR 1992
Query: 130 RHDNR------RRSRSKSKPPKRDEKERKRRSPS 157
R +R RRSRS++ P R + R R P+
Sbjct: 1993 RSRSRTSPVTRRRSRSRTSPVTR-RRSRSRTPPA 2025
Score = 47.0 bits (110), Expect = 2e-05
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 27/164 (16%)
Query: 17 NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR 76
+ +K+ +R R + S E K R + + SS + + + + RRS S S +
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787
Query: 77 SRSSST---SSSGSSTSTGSSS-----GSSSSSASSRSGSSSTSRSSSSSSS------SG 122
+S + S SGSS S SSSS + S + SR S SSSS SG
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSG 847
Query: 123 SP-------SPSRRRHD--NRRRSRSKSKPPKRDEKERKRRSPS 157
+P SP +RRS +S P + E K R+PS
Sbjct: 848 TPPRQGSITSPQANEQSVTPQRRSCFESSP----DPELKSRTPS 887
Score = 42.4 bits (98), Expect = 5e-04
Identities = 82/344 (23%), Positives = 120/344 (34%), Gaps = 73/344 (21%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT----RKRRSASSGSSS 74
K+ STR+ + S E S D + G + S D + RS+S+ S
Sbjct: 1372 KEQSTRSSGHS-----SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426
Query: 75 TRSRSSSTSS--SGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSG------SPSP 126
+ T S S S +S G GS + S S SGSS + + S G SP P
Sbjct: 1427 MKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP 1486
Query: 127 SRRRHDNRRRSRSKSKP--------PKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHI- 177
R RSRS S P P+R+ + + +G+ +R+ + +
Sbjct: 1487 KALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 178 --------------------------MEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEF- 210
+ S G +D R+ P S+ + E
Sbjct: 1547 VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK-SRLSPRRSRSGSSPEVK 1605
Query: 211 ENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPR--RFSPPRRMLPPPPMWRRS-- 266
+ P A +A D ++ AP PR PR R + P P S
Sbjct: 1606 DKPRAAPRAQSGSD---------SSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656
Query: 267 -----PPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR 305
PP+ R R R + +SR+P RRR SRSS +R
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRR-SSRSSPELTR 1699
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/312 (23%), Positives = 101/312 (32%), Gaps = 39/312 (12%)
Query: 25 APSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSST-- 82
A + T + +EK +R + +S D R+ R A + S
Sbjct: 117 AVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRE 176
Query: 83 SSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSG---SPSPSRRRHDNRRRSRS 139
SSS S + RS SSS R SS S S S++R R
Sbjct: 177 SSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR--KHRSPTP 234
Query: 140 KSKPPKRDEKERKRRS--PSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERM 197
KSK +D+K ++ RS P+PK + H + + S K +
Sbjct: 235 KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGR 294
Query: 198 HPHLSKGY-----------AYVEFENPDEAEKALKH----MDGGQIDGQEITATAVLAPW 242
P + G + P E A K + D +E +AT
Sbjct: 295 SPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR----- 349
Query: 243 PRPPPRRFSP-PRRMLPPPPMWRR---------SPPRMRRRSRSPRRRSPVRRRSRSPGR 292
P P P R S P P P + R + P + P SP R RS
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409
Query: 293 RRHRSRSSSNSS 304
+ SSS SS
Sbjct: 410 EKLPQSSSSESS 421
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 5/115 (4%)
Query: 19 KKSSTRAPSPTKRKDRSDE----KSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSS 74
++S +R P +R+ RS + + RS+ A + S + R R +RS + +
Sbjct: 2016 RRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRS-RSRTPRTARGKRSLTRSPPA 2074
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRR 129
R RS+S SSS S S + + S + + + ++SR S S S SP+P R
Sbjct: 2075 IRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDR 2129
Score = 39.3 bits (90), Expect = 0.004
Identities = 66/273 (24%), Positives = 99/273 (36%), Gaps = 33/273 (12%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT-----RKRRSASSGSS 73
++S +R T+R+ RS R + + T + + R R +T R+ RS +
Sbjct: 1980 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR-RSRSRTPPAIRRRSRSRTPLLP 2038
Query: 74 STRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS---PSRRR 130
RSRS S + + + + + + +RS + RS+S SSS S S P+ R
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
Query: 131 HDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMI 190
H R + R SP+P G L + M + G M+
Sbjct: 2099 HSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGG-SMM 2157
Query: 191 DMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRF 250
D P R+ H EN ++ AL TA+ RPPP
Sbjct: 2158 DGPGPRIPDHQRTSVP----ENHAQSRIAL-------------ALTAISLGTARPPPSMS 2200
Query: 251 SP--PRRM----LPPPPMWRRSPPRMRRRSRSP 277
+ RM P P M R+ P SR P
Sbjct: 2201 AAGLAARMSQVPAPVPLMSLRTAPAANLASRIP 2233
Score = 35.4 bits (80), Expect = 0.063
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Query: 47 GATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS 106
G + E E G + S +RSS SSS S +G SS+ + S
Sbjct: 1346 GFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405
Query: 107 GSSSTSRSSSSSSSSGSPSPSRRRHDNR---RRSRSKSKPPKRD 147
+ R+ S SS + SP + R RRSRS S P RD
Sbjct: 1406 VLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
Score = 34.3 bits (77), Expect = 0.14
Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 14/156 (8%)
Query: 20 KSSTRAPSPTKR---KDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSS--- 73
+++ ++ +P +R + D + K R+ + + SS R + T R+S S SS
Sbjct: 859 QANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP-RVKSSTPPRQSPSRSSSPQP 917
Query: 74 ------STRSRSSSTSSSGS-STSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
S R RS S SSS S S T ++ S S S S S S S S SP
Sbjct: 918 KVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDT 977
Query: 127 SRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
+ R+S S S P K + PS +K
Sbjct: 978 KVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK 1013
Score = 33.9 bits (76), Expect = 0.18
Identities = 34/130 (26%), Positives = 46/130 (35%), Gaps = 1/130 (0%)
Query: 21 SSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80
S R S T + S + K K G R +S ++ RSRS
Sbjct: 895 SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR-VTSRTTPRRSRSV 953
Query: 81 STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140
S S+ S S S SSS ++ + R S S S S P + S SK
Sbjct: 954 SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK 1013
Query: 141 SKPPKRDEKE 150
S P+ K+
Sbjct: 1014 SPCPQEKSKD 1023
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 75.9 bits (185), Expect = 4e-14
Identities = 61/160 (38%), Positives = 80/160 (50%), Gaps = 16/160 (10%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSS 74
KE+ + +K K DE D K S E+D + K+ +R + S SS
Sbjct: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSAS-SRSGSSSTSRS------SSSSSSSGSPSPS 127
+RS S S+S S S + + S S SSSSS S SRS S SRS SSS S GS SP
Sbjct: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
Query: 128 RRRHD--------NRRRSRSKSKPPKRDEKERKRRSPSPK 159
+R + NR+RSRS+S D K+R+ RS SP+
Sbjct: 271 KRSYSSSSSSPERNRKRSRSRSS-SSGDRKKRRTRSRSPE 309
Score = 65.5 bits (158), Expect = 6e-11
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASS---G 71
+ ++ +SS+R+ SP+ + RS +S+ S + ++ SS ++R R + K RS+S G
Sbjct: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS-RERSRSRGSKSRSSSRSHRG 265
Query: 72 SSSTRSRSSSTSSSG------SSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS 125
SSS R RS S+SSS S S SSSG + RSSS SS SGS S
Sbjct: 266 SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRS 325
Query: 126 PSRRR 130
S+++
Sbjct: 326 SSKKK 330
Score = 43.1 bits (100), Expect = 3e-04
Identities = 45/155 (29%), Positives = 63/155 (40%), Gaps = 28/155 (18%)
Query: 19 KKSSTRAPSPT---KRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSST 75
KK +A P K + + + ++ +D+ +K ++D D
Sbjct: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED--------------- 176
Query: 76 RSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS-SSTSRSSSSSSSSGSPSPSRRRHDNR 134
+ S S S S+ SRS S SS SRSSS SS SPS SR R +R
Sbjct: 177 ---DADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSS---SPSSSRSRSRSR 230
Query: 135 RRSRSKSKPPKRD---EKERKRRSPSPKPTKVHIG 166
RS S S+ R E+ R R S S ++ H G
Sbjct: 231 SRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG 265
Score = 34.3 bits (77), Expect = 0.14
Identities = 20/41 (48%), Positives = 24/41 (58%)
Query: 264 RRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSS 304
++S R R +SRS RS R S S R R RSRS S+SS
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSS 236
Score = 33.5 bits (75), Expect = 0.24
Identities = 23/43 (53%), Positives = 25/43 (58%), Gaps = 5/43 (11%)
Query: 266 SPPRMRRRSRSPRR----RSPVRRRSRSPGRRRHRSRSSSNSS 304
SP R R+RSRS R R RSRSP RRHRS S S+ S
Sbjct: 280 SPERNRKRSRSRSSSSGDRKKRRTRSRSP-ERRHRSSSGSSHS 321
Score = 32.3 bits (72), Expect = 0.54
Identities = 22/43 (51%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 265 RSPPRMRRRSRSPRRRSPVRRRSRSP--GRRRHRSRSSSNSSR 305
RS R R S SPR+RS S SP R+R RSRSSS+ R
Sbjct: 257 RSSSRSHRGSSSPRKRS-YSSSSSSPERNRKRSRSRSSSSGDR 298
Score = 31.2 bits (69), Expect = 1.2
Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 266 SPPRMRRRSRS-PRRRSPVRRRSRSPGRRRHRSRSSSNSS 304
SP R RSRS R S + RSRS R R RSR S + S
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
Score = 29.3 bits (64), Expect = 4.5
Identities = 24/55 (43%), Positives = 26/55 (47%), Gaps = 16/55 (29%)
Query: 265 RSPPRMRRRSR---------------SPRRRSPVRRRSRSPGRRRHRSRSSSNSS 304
RS R R RSR SPR+RS S SP R R RSRS S+SS
Sbjct: 242 RSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS-YSSSSSSPERNRKRSRSRSSSS 295
Score = 28.5 bits (62), Expect = 7.7
Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 264 RRSPPRMRRRSRSPRR-RSPVRRRSRSPGRRRHRSRSSS 301
R S R RS SP RS R RSRS + RSRSSS
Sbjct: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS 245
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 75.9 bits (185), Expect = 4e-14
Identities = 61/160 (38%), Positives = 80/160 (50%), Gaps = 16/160 (10%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSS 74
KE+ + +K K DE D K S E+D + K+ +R + S SS
Sbjct: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSAS-SRSGSSSTSRS------SSSSSSSGSPSPS 127
+RS S S+S S S + + S S SSSSS S SRS S SRS SSS S GS SP
Sbjct: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
Query: 128 RRRHD--------NRRRSRSKSKPPKRDEKERKRRSPSPK 159
+R + NR+RSRS+S D K+R+ RS SP+
Sbjct: 271 KRSYSSSSSSPERNRKRSRSRSS-SSGDRKKRRTRSRSPE 309
Score = 55.8 bits (133), Expect = 5e-08
Identities = 39/106 (36%), Positives = 59/106 (55%), Gaps = 5/106 (4%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASS---G 71
+ ++ +SS+R+ SP+ + RS +S+ S + ++ SS ++R R + K RS+S G
Sbjct: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS-RERSRSRGSKSRSSSRSHRG 265
Query: 72 SSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117
SSS R RS S+SSS S S S SSS+ R + SRS S
Sbjct: 266 SSSPRKRSYSSSSS-SPERNRKRSRSRSSSSGDRKKRRTRSRSPES 310
Score = 43.1 bits (100), Expect = 3e-04
Identities = 45/155 (29%), Positives = 63/155 (40%), Gaps = 28/155 (18%)
Query: 19 KKSSTRAPSPT---KRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSST 75
KK +A P K + + + ++ +D+ +K ++D D
Sbjct: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED--------------- 176
Query: 76 RSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS-SSTSRSSSSSSSSGSPSPSRRRHDNR 134
+ S S S S+ SRS S SS SRSSS SS SPS SR R +R
Sbjct: 177 ---DADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSS---SPSSSRSRSRSR 230
Query: 135 RRSRSKSKPPKRD---EKERKRRSPSPKPTKVHIG 166
RS S S+ R E+ R R S S ++ H G
Sbjct: 231 SRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG 265
Score = 34.3 bits (77), Expect = 0.14
Identities = 20/41 (48%), Positives = 24/41 (58%)
Query: 264 RRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSS 304
++S R R +SRS RS R S S R R RSRS S+SS
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSS 236
Score = 32.3 bits (72), Expect = 0.54
Identities = 22/43 (51%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 265 RSPPRMRRRSRSPRRRSPVRRRSRSP--GRRRHRSRSSSNSSR 305
RS R R S SPR+RS S SP R+R RSRSSS+ R
Sbjct: 257 RSSSRSHRGSSSPRKRS-YSSSSSSPERNRKRSRSRSSSSGDR 298
Score = 31.2 bits (69), Expect = 1.2
Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 266 SPPRMRRRSRS-PRRRSPVRRRSRSPGRRRHRSRSSSNSS 304
SP R RSRS R S + RSRS R R RSR S + S
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
Score = 29.3 bits (64), Expect = 4.5
Identities = 24/55 (43%), Positives = 26/55 (47%), Gaps = 16/55 (29%)
Query: 265 RSPPRMRRRSR---------------SPRRRSPVRRRSRSPGRRRHRSRSSSNSS 304
RS R R RSR SPR+RS S SP R R RSRS S+SS
Sbjct: 242 RSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS-YSSSSSSPERNRKRSRSRSSSS 295
Score = 28.5 bits (62), Expect = 7.7
Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 264 RRSPPRMRRRSRSPRR-RSPVRRRSRSPGRRRHRSRSSS 301
R S R RS SP RS R RSRS + RSRSSS
Sbjct: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS 245
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 75.5 bits (184), Expect = 6e-14
Identities = 81/297 (27%), Positives = 114/297 (38%), Gaps = 35/297 (11%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRR 66
K +S + +KK +R+PS K + RS K RSK K +E + + K K R
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP-KSR 289
Query: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
S S S ++SRS S GS S S S R S + S S S S S
Sbjct: 290 SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK 349
Query: 127 SRRRHDNRRRSR--SKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTY 184
S+ + R+RSR S+S+ R + ER R+ S + +K + + D +
Sbjct: 350 SKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR------SQ 403
Query: 185 GKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPR 244
+ + ER H + Q +G+ + A R
Sbjct: 404 SRSPSRSVSKEREH----------------------AKSESSQREGRGESENAGTNQETR 441
Query: 245 PPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSS 301
R S + LP RS + RSRS +S R SRSP R R RS S S
Sbjct: 442 SRSRSNSKSKPNLPSESR-SRSKSASKTRSRS---KSRSRSASRSPSRSRSRSHSRS 494
Score = 62.0 bits (149), Expect = 6e-10
Identities = 40/140 (28%), Positives = 69/140 (49%), Gaps = 4/140 (2%)
Query: 13 GVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR-RSASSG 71
G + S +R+ S ++ + R KS+ RS G++K S K R R ++ R RS S
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS---GSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 72 SSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRH 131
S +RSRS S S S S+ + S+S + + ++ + S S RH
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 132 DNRRRSRSKSKPPKRDEKER 151
++ +SRS+S+ + +E++R
Sbjct: 295 KSKSKSRSRSQERRVEEEKR 314
Score = 61.2 bits (147), Expect = 1e-09
Identities = 42/98 (42%), Positives = 54/98 (55%), Gaps = 7/98 (7%)
Query: 62 TRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSAS-SRSGSSSTSRSSSSSSS 120
+R+RRS S S +RSRS S S S + +GSS S S S S SRSGS S S+S S S S
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 121 SG------SPSPSRRRHDNRRRSRSKSKPPKRDEKERK 152
S SPS+ + +R S KS+ +D+ E K
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK 276
Score = 58.5 bits (140), Expect = 7e-09
Identities = 49/128 (38%), Positives = 64/128 (50%), Gaps = 13/128 (10%)
Query: 44 KDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSAS 103
+DK ++ R R +R R S S S +RSRS S+ SS S + + S SGS S S
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSR-SRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS-- 230
Query: 104 SRSGSSSTSRSSSSSSSSGSPS--PSRRRHDNRRRSRSKSKPPKRDEKER-------KRR 154
+S S S SRS S S SPS SR R + +SRSKSK ++ + K R
Sbjct: 231 -KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 155 SPSPKPTK 162
SPS +K
Sbjct: 290 SPSRHKSK 297
Score = 52.0 bits (123), Expect = 7e-07
Identities = 62/218 (28%), Positives = 88/218 (40%), Gaps = 35/218 (16%)
Query: 100 SSASSRSGSSSTSRS---------SSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRD-EK 149
S + SRS S S SRS S SS SS S S SR R +R RS+S+S+ R K
Sbjct: 184 SYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSK 243
Query: 150 ERKRRSPSPKP--TKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAY 207
+ K RSPS + ++ H +R+ +KD E + H SK +
Sbjct: 244 KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR 303
Query: 208 VEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSP 267
+ +E ++ G + ++ R + S RS
Sbjct: 304 SQERRVEEEKR-------GSVSRGRSQEKSLRQSRSRSRSKGGS-------------RSR 343
Query: 268 PRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR 305
R R +S+ R+ R+RSR R R RSRS S SR
Sbjct: 344 SRSRSKSKDKRKG---RKRSREESRSRSRSRSKSERSR 378
Score = 52.0 bits (123), Expect = 7e-07
Identities = 42/115 (36%), Positives = 59/115 (51%), Gaps = 10/115 (8%)
Query: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
S KKK KE+ +S +R+PS + K+R KS+ ++ E++ G ++
Sbjct: 390 SSKKKK-----KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA----GTNQET 440
Query: 64 KRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
+ RS S+ S S S S S S++ T S S S S SAS RS S S SRS S S
Sbjct: 441 RSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS-RSPSRSRSRSHSRS 494
Score = 43.5 bits (101), Expect = 2e-04
Identities = 47/185 (25%), Positives = 73/185 (39%), Gaps = 26/185 (14%)
Query: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIF 181
GS R + RR R K PP R E ++ + L+ + + +
Sbjct: 77 GSYGSGRSGYGYRRSGRDKYGPPTRTEY------------RLIVENLSSRCSWQDLKDYM 124
Query: 182 STYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAP 241
G++ D R K +EF + + ++AL+ +DG +++G++I
Sbjct: 125 RQAGEVTYADAHKGR------KNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE---- 174
Query: 242 WPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSP---VRRRSRSPGRRRHRSR 298
+P RR R RS + RSRS +S R RSRS R R +SR
Sbjct: 175 -DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 299 SSSNS 303
S S S
Sbjct: 234 SRSQS 238
Score = 41.6 bits (96), Expect = 9e-04
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 9/80 (11%)
Query: 162 KVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALK 221
+V+IGRL+ + + F YGKI +D L GY +VEF++ +A+ A+
Sbjct: 3 RVYIGRLSYQARERDVERFFKGYGKILEVD---------LKNGYGFVEFDDLRDADDAVY 53
Query: 222 HMDGGQIDGQEITATAVLAP 241
++G + G+ + P
Sbjct: 54 ELNGKDLCGERVIVEHARGP 73
Score = 40.4 bits (93), Expect = 0.002
Identities = 57/199 (28%), Positives = 77/199 (38%), Gaps = 32/199 (16%)
Query: 110 STSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLT 169
S R S S S S S S SR RH + RSRS S + + RS S +K +
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 170 RNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQID 229
R+ +K K + R H S G + ++ D+AE+ +++ D
Sbjct: 239 RSRSKKE---------KSRSPSKEKSRSRSH-SAGKS--RSKSKDQAEEKIQNNDN---- 282
Query: 230 GQEITATAVLAPWPRPPPRRFSPPRRMLPPPPM-----WRRSPPRMRRRSRSPRRRSPVR 284
V P R P R S + R S R R + +S R+ R
Sbjct: 283 --------VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS---R 331
Query: 285 RRSRSPGRRRHRSRSSSNS 303
RSRS G R RSRS S S
Sbjct: 332 SRSRSKGGSRSRSRSRSKS 350
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 74.3 bits (181), Expect = 1e-13
Identities = 47/103 (45%), Positives = 62/103 (60%)
Query: 21 SSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80
SS+ + S + + E+ D++ D G + S+SS SSS+ S SS
Sbjct: 2568 SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627
Query: 81 STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGS 123
S+SSS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSSS S
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
Score = 73.6 bits (179), Expect = 2e-13
Identities = 52/135 (38%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
Query: 13 GVKENNKKSSTRAPSPTKRKDRSDEKSKDRSK---DKGATKESSEKDRGRDKTRKRRSAS 69
G +E+ SS+ + S + S S+ + DK R R ++
Sbjct: 2553 GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASP 2612
Query: 70 SGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRR 129
+ SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSSS S S S
Sbjct: 2613 ASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 2672
Query: 130 RHDNRRRSRSKSKPP 144
++ S P
Sbjct: 2673 TDEDSSCSSDDEAAP 2687
Score = 67.0 bits (162), Expect = 2e-11
Identities = 49/136 (36%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 18 NKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRS 77
N KS +A + + S+ S S ++ SS + + G T
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
Query: 78 RSSSTSSS-----GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHD 132
R+ S +SS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSSS S S S
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
Query: 133 NRRRSRSKSKPPKRDE 148
+ S S S DE
Sbjct: 2660 SSSSSSSSSSSSTTDE 2675
Score = 62.8 bits (151), Expect = 4e-10
Identities = 46/150 (30%), Positives = 71/150 (47%), Gaps = 19/150 (12%)
Query: 17 NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR 76
N +S+RA SP S S S ++ SS +SS SSS+
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS--------------SSSSSSSSS 2646
Query: 77 SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRR 136
S SSS+SSS SS+S+ SSS SSSSS + S S+ ++ + ++G PS +
Sbjct: 2647 SSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG-PSAQAALPTKATK 2705
Query: 137 SRSKSKP----PKRDEKERKRRSPSPKPTK 162
K++P P + + ++P P+PT+
Sbjct: 2706 QAGKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735
Score = 60.5 bits (145), Expect = 2e-09
Identities = 55/160 (34%), Positives = 69/160 (43%), Gaps = 43/160 (26%)
Query: 40 KDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSS--------------- 84
+D K K +E+D G +++ S+SSGSSS SSS+SS
Sbjct: 2536 EDSGNPKSPDKAQAEQD-GAEESESSSSSSSGSSS----SSSSSSSSGSETEGEEEGDKN 2590
Query: 85 -----------------------SGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
S SS+S+ SSS SSSSS+SS S SSS+S SSSSSSSS
Sbjct: 2591 GDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2650
Query: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPT 161
S S S + S S S D +P PT
Sbjct: 2651 SSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPT 2690
Score = 35.0 bits (79), Expect = 0.083
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Query: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
G T S + S + + + S SS+SS SGSSS SSSSSSSSGS +
Sbjct: 2530 GPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSS---SSSSSSSSGSETEGEEE 2586
Query: 131 HD 132
D
Sbjct: 2587 GD 2588
Score = 34.3 bits (77), Expect = 0.14
Identities = 46/198 (23%), Positives = 74/198 (37%), Gaps = 36/198 (18%)
Query: 81 STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140
S + S + G SSG+ + +SSR G + + G P P + D R R
Sbjct: 178 SHAPSARTPGGGHSSGAPAKGSSSRDGPAK-----ERAGRGGEPPPLFGKKDPRARGEEA 232
Query: 141 SKP-------PKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME---IFSTYGKIKMI 190
S P + + R+ R P P+ + L + TK+ ++ + G +
Sbjct: 233 SGPRGVVDLTQEARAEGRQDRGP-PRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDV 291
Query: 191 DMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRF 250
+P A V A++A + +G ++ + T L P PRP P
Sbjct: 292 GLP------------ALVAEAGRGGAKEAARQDEGARL----LRRTETLLPGPRPCPSPL 335
Query: 251 SPPRRMLPPPPMWRRSPP 268
PP P PP +PP
Sbjct: 336 PPP----PAPPKGPPAPP 349
Score = 34.3 bits (77), Expect = 0.14
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 248 RRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRS 289
RR S RR P + RR P R R+R+ +P SP R+R +S
Sbjct: 1507 RRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKS 1548
Score = 32.7 bits (73), Expect = 0.41
Identities = 35/151 (23%), Positives = 52/151 (34%), Gaps = 36/151 (23%)
Query: 43 SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSA 102
S+ K ++++ D ++ SG+ + ++ + + + SSS S SSS+
Sbjct: 2511 SEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSS 2570
Query: 103 SSRSGSS------------------------------------STSRSSSSSSSSGSPSP 126
SS S SS S+S SSSSSSSS S S
Sbjct: 2571 SSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSS 2630
Query: 127 SRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
S + S S S S S
Sbjct: 2631 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
Score = 29.6 bits (65), Expect = 3.5
Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 30 KRKDRSDEKSKDR--SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGS 87
K K R K + R S+D+ S RG + RKR A S S R R S SSG
Sbjct: 1495 KEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGK 1554
Query: 88 STS 90
+S
Sbjct: 1555 LSS 1557
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 74.3 bits (181), Expect = 1e-13
Identities = 86/296 (29%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGA------TKESSEKDRGRDK--TRKRRSASSGSS 73
S +P + +R+ E S + D T E S+K++ RDK K+R +S S
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 74 STRSRSSSTSS-SGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHD 132
S RS+SS S +S S + SS S S RS + S SRS SS S S SR R
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRS 1885
Query: 133 NRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDM 192
+ R +S + +ERKR+ S + + + +R ++
Sbjct: 1886 VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR----------------- 1928
Query: 193 PVERMH-PHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFS 251
R H P + V + + + + + R P RR
Sbjct: 1929 --SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1986
Query: 252 PPRRMLPPPPMWRRSPPRMRRRS------RSPRRRSPVRRR-SRSPGRRRHRSRSS 300
P R P RRS +RRRS R R R+P+RRR SRSP RR+ RSRSS
Sbjct: 1987 TPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRK-RSRSS 2041
Score = 64.3 bits (155), Expect = 1e-10
Identities = 52/155 (33%), Positives = 74/155 (47%), Gaps = 23/155 (14%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK--------DRGRDKTRKRR 66
K + +S TR+ S ++R+ RS S+ RSK +G S EK + R++ RKR
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRS---SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRS 1909
Query: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
S+ + R+RS + S S S + S RS S RS S S S S +P
Sbjct: 1910 SSRDNRKTVRARSRTPSRR---------SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTP 1960
Query: 127 SRRRHDNRRRSRS---KSKPPKRDEKERKRRSPSP 158
SRR RRSR+ +S+ P R + RRS +P
Sbjct: 1961 SRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995
Score = 61.6 bits (148), Expect = 8e-10
Identities = 52/165 (31%), Positives = 73/165 (44%), Gaps = 21/165 (12%)
Query: 13 GVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKG--ATKESSEKDRGRDKTRKRRSASS 70
G KE + SS R+ S KR S+ KS+ R+ + A K SS+ R +TR R +
Sbjct: 1812 GEKEKKRDSSLRSRS--KRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869
Query: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
S+RSRS S S S S + R S+SR + + + S +PSRR
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929
Query: 131 HDN----RRRSRS-------------KSKPPKRDEKERKRRSPSP 158
+ RRRSRS +S+ P R + RRS +P
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTP 1974
Score = 56.6 bits (135), Expect = 3e-08
Identities = 48/147 (32%), Positives = 62/147 (42%), Gaps = 10/147 (6%)
Query: 16 ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSAS-SGSSS 74
E +KK+ R ++K S +S+ + K R + RKR S S S S
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNR 134
TRSRS S SS S S G S S R S S S S SR DNR
Sbjct: 1861 TRSRSRSRRRRRSSRSRSKSRGRRSVSKEKR--KRSPKHRSKSRERKRKRSSSR---DNR 1915
Query: 135 RRSRSKSKPPKRDEK----ERKRRSPS 157
+ R++S+ P R + R+RRS S
Sbjct: 1916 KTVRARSRTPSRRSRSHTPSRRRRSRS 1942
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKR 65
K + V + +K S + S ++ + R S+D K + ++ S + R +R+R
Sbjct: 1879 KSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR 1938
Query: 66 RSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS 125
RS S G R RS S S S S + S + S + + S S T S + S S +
Sbjct: 1939 RSRSVG----RRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1994
Query: 126 PSRRRHDN---RRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
PSRRR RRRS S S R + RR S P +
Sbjct: 1995 PSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIR 2034
Score = 47.0 bits (110), Expect = 2e-05
Identities = 46/147 (31%), Positives = 65/147 (44%), Gaps = 8/147 (5%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRR 66
+K+ ++N K R+ +P++R + RS+ G + S R +T RR
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRR 1963
Query: 67 SAS-SGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS 125
S + S S T SR S T S S T + S + S SRS S S S S +
Sbjct: 1964 SRTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 126 PSRRRHD----NRRRSRS--KSKPPKR 146
P RRR R+RSRS + + PKR
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 36.6 bits (83), Expect = 0.028
Identities = 30/68 (44%), Positives = 34/68 (50%), Gaps = 10/68 (14%)
Query: 248 RRFSPPRRMLPPPPMWRRSPPR-----MRRRSRSPRRRSPV-----RRRSRSPGRRRHRS 297
R+ SP R +RS R +R RSR+P RRS RRRSRS GRRR S
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950
Query: 298 RSSSNSSR 305
S S SR
Sbjct: 1951 ISPSRRSR 1958
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/46 (50%), Positives = 24/46 (52%), Gaps = 4/46 (8%)
Query: 264 RRSPPRMRRRSRSPR---RRSPVRRRSRSPGRRR-HRSRSSSNSSR 305
R S R R R RS + RS R RSRS RRR RSRS S R
Sbjct: 1839 RTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Score = 30.0 bits (66), Expect = 2.7
Identities = 23/52 (44%), Positives = 25/52 (48%), Gaps = 11/52 (21%)
Query: 265 RSPPRMRRRSRSPRRRSPVRR------RSRSP-----GRRRHRSRSSSNSSR 305
RS R RRRS R +S RR R RSP R R R RSSS +R
Sbjct: 1864 RSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNR 1915
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 74.3 bits (181), Expect = 1e-13
Identities = 86/296 (29%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGA------TKESSEKDRGRDK--TRKRRSASSGSS 73
S +P + +R+ E S + D T E S+K++ RDK K+R +S S
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 74 STRSRSSSTSS-SGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHD 132
S RS+SS S +S S + SS S S RS + S SRS SS S S SR R
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRS 1885
Query: 133 NRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDM 192
+ R +S + +ERKR+ S + + + +R ++
Sbjct: 1886 VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR----------------- 1928
Query: 193 PVERMH-PHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFS 251
R H P + V + + + + + R P RR
Sbjct: 1929 --SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1986
Query: 252 PPRRMLPPPPMWRRSPPRMRRRS------RSPRRRSPVRRR-SRSPGRRRHRSRSS 300
P R P RRS +RRRS R R R+P+RRR SRSP RR+ RSRSS
Sbjct: 1987 TPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRK-RSRSS 2041
Score = 64.3 bits (155), Expect = 1e-10
Identities = 52/155 (33%), Positives = 74/155 (47%), Gaps = 23/155 (14%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK--------DRGRDKTRKRR 66
K + +S TR+ S ++R+ RS S+ RSK +G S EK + R++ RKR
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRS---SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRS 1909
Query: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
S+ + R+RS + S S S + S RS S RS S S S S +P
Sbjct: 1910 SSRDNRKTVRARSRTPSRR---------SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTP 1960
Query: 127 SRRRHDNRRRSRS---KSKPPKRDEKERKRRSPSP 158
SRR RRSR+ +S+ P R + RRS +P
Sbjct: 1961 SRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995
Score = 61.6 bits (148), Expect = 8e-10
Identities = 52/165 (31%), Positives = 73/165 (44%), Gaps = 21/165 (12%)
Query: 13 GVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKG--ATKESSEKDRGRDKTRKRRSASS 70
G KE + SS R+ S KR S+ KS+ R+ + A K SS+ R +TR R +
Sbjct: 1812 GEKEKKRDSSLRSRS--KRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869
Query: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
S+RSRS S S S S + R S+SR + + + S +PSRR
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929
Query: 131 HDN----RRRSRS-------------KSKPPKRDEKERKRRSPSP 158
+ RRRSRS +S+ P R + RRS +P
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTP 1974
Score = 56.6 bits (135), Expect = 3e-08
Identities = 48/147 (32%), Positives = 62/147 (42%), Gaps = 10/147 (6%)
Query: 16 ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSAS-SGSSS 74
E +KK+ R ++K S +S+ + K R + RKR S S S S
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ 1860
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNR 134
TRSRS S SS S S G S S R S S S S SR DNR
Sbjct: 1861 TRSRSRSRRRRRSSRSRSKSRGRRSVSKEKR--KRSPKHRSKSRERKRKRSSSR---DNR 1915
Query: 135 RRSRSKSKPPKRDEK----ERKRRSPS 157
+ R++S+ P R + R+RRS S
Sbjct: 1916 KTVRARSRTPSRRSRSHTPSRRRRSRS 1942
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKR 65
K + V + +K S + S ++ + R S+D K + ++ S + R +R+R
Sbjct: 1879 KSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR 1938
Query: 66 RSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS 125
RS S G R RS S S S S + S + S + + S S T S + S S +
Sbjct: 1939 RSRSVG----RRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1994
Query: 126 PSRRRHDN---RRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
PSRRR RRRS S S R + RR S P +
Sbjct: 1995 PSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIR 2034
Score = 47.0 bits (110), Expect = 2e-05
Identities = 46/147 (31%), Positives = 65/147 (44%), Gaps = 8/147 (5%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRR 66
+K+ ++N K R+ +P++R + RS+ G + S R +T RR
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRR 1963
Query: 67 SAS-SGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS 125
S + S S T SR S T S S T + S + S SRS S S S S +
Sbjct: 1964 SRTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 126 PSRRRHD----NRRRSRS--KSKPPKR 146
P RRR R+RSRS + + PKR
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 36.6 bits (83), Expect = 0.028
Identities = 30/68 (44%), Positives = 34/68 (50%), Gaps = 10/68 (14%)
Query: 248 RRFSPPRRMLPPPPMWRRSPPR-----MRRRSRSPRRRSPV-----RRRSRSPGRRRHRS 297
R+ SP R +RS R +R RSR+P RRS RRRSRS GRRR S
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950
Query: 298 RSSSNSSR 305
S S SR
Sbjct: 1951 ISPSRRSR 1958
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/46 (50%), Positives = 24/46 (52%), Gaps = 4/46 (8%)
Query: 264 RRSPPRMRRRSRSPR---RRSPVRRRSRSPGRRR-HRSRSSSNSSR 305
R S R R R RS + RS R RSRS RRR RSRS S R
Sbjct: 1839 RTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Score = 30.0 bits (66), Expect = 2.7
Identities = 23/52 (44%), Positives = 25/52 (48%), Gaps = 11/52 (21%)
Query: 265 RSPPRMRRRSRSPRRRSPVRR------RSRSP-----GRRRHRSRSSSNSSR 305
RS R RRRS R +S RR R RSP R R R RSSS +R
Sbjct: 1864 RSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNR 1915
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 73.6 bits (179), Expect = 2e-13
Identities = 60/191 (31%), Positives = 97/191 (50%), Gaps = 12/191 (6%)
Query: 53 SEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTS 112
S+ + + R+ RS S + T +R S S SGS + + S S S S S RS S S S
Sbjct: 2 SDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRS-RSKSRSRS 60
Query: 113 RSSSSSSSSGSPSPS---RRRHDNR------RRSRSKSKPPKRDEKERKRRSPSPKP-TK 162
R S + S S S RRR +R RR RS+S P + + +P P T
Sbjct: 61 RRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTC 120
Query: 163 VHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKH 222
+ + L+ T+ + E+FS YG + +++ V S+G+A+V FE D++++A++
Sbjct: 121 LGVFGLSLYTTERDLREVFSRYGPLSGVNV-VYDQRTGRSRGFAFVYFERIDDSKEAMER 179
Query: 223 MDGGQIDGQEI 233
+G ++DG+ I
Sbjct: 180 ANGMELDGRRI 190
Score = 32.7 bits (73), Expect = 0.41
Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 253 PRRMLPPPPMWRRSPPRMRRRSRS-PRRRSPVRRRSRSPGRRRH-RSRSSSNSSR 305
P R+ RSP R+ + S S R RS R RSR RR+ RSRS S+S R
Sbjct: 25 PARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHR 79
Score = 30.4 bits (67), Expect = 2.0
Identities = 20/36 (55%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 269 RMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSS 304
R R S S RRRS R RS +P RR RSRS S S
Sbjct: 70 RSRSHSHSHRRRS--RSRSYTPEYRRRRSRSHSPMS 103
>gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens]
Length = 164
Score = 72.4 bits (176), Expect = 5e-13
Identities = 56/154 (36%), Positives = 71/154 (46%), Gaps = 22/154 (14%)
Query: 154 RSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENP 213
R P KV++G L N K + F YG ++ + V R P G+A+VEFE+P
Sbjct: 3 RDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVW--VARNPP----GFAFVEFEDP 56
Query: 214 DEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSP-PRMRR 272
+A A++ +DG + G + R R PPP W R P RR
Sbjct: 57 RDAADAVRELDGRTLCGCRV----------RVELSNGEKRSRNRGPPPSWGRRPRDDYRR 106
Query: 273 RSRSPRRRSPVRR-----RSRSPGRRRHRSRSSS 301
RS PRRRSP RR RSRS R R R RS S
Sbjct: 107 RSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLS 140
Score = 30.0 bits (66), Expect = 2.7
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 8/62 (12%)
Query: 24 RAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR-RSASSGSSSTRSRSSST 82
R+P P +R R S+ RS+ S +DR R+++ R R+ S +RSRS S
Sbjct: 107 RSPPPRRRSPRRRSFSRSRSR-------SLSRDRRRERSLSRERNHKPSRSFSRSRSRSR 159
Query: 83 SS 84
S+
Sbjct: 160 SN 161
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 71.2 bits (173), Expect = 1e-12
Identities = 103/373 (27%), Positives = 138/373 (36%), Gaps = 109/373 (29%)
Query: 24 RAPSPTK--RKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSS------- 74
+ PSP K +K++ EK++ RS+ + ++ S + R TR RR S S S
Sbjct: 257 KEPSPEKNSKKEKEKEKTRPRSRSRSKSR-SRTRSRSPSHTRPRRRHRSRSRSYSPRRRP 315
Query: 75 --------------------TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS 114
R R S + S+ S SGSSSSS+SSRS S
Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375
Query: 115 SSSSSS-------SGSPSPSRRRH--------------------DNRRRSRSKSKPPKRD 147
+SS S S SP RRRH NR R S P R
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
Query: 148 E---------KERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVE--- 195
++R+ SP+PKP KV + + GK+ D +
Sbjct: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEED-----------KGGKMAAADSVQQRRQ 484
Query: 196 -RMHPHLSKGYAYVEFENPDEAEKALKHMDGGQID-GQEITATAVLAPWPR--------- 244
R S + + DE K H+ G++ + + + +P PR
Sbjct: 485 YRRQNQQSSSDSGSSSSSEDERPKR-SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR 543
Query: 245 --------PPP--RRFSPP------RRMLPPPPMWRRSP-PRMRRRSRSPRRRSPVRRRS 287
PPP RR SP RR P PP RR+P P RRRS SPRR SP +R
Sbjct: 544 GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRR 603
Query: 288 RSPGRRRHRSRSS 300
SP R +S
Sbjct: 604 YSPSPPPKRRTAS 616
Score = 67.8 bits (164), Expect = 1e-11
Identities = 86/307 (28%), Positives = 114/307 (37%), Gaps = 59/307 (19%)
Query: 28 PTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGS 87
P+ + E+ K R ++ ++D +DK K SS RSRS S S
Sbjct: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRS 179
Query: 88 STSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRD 147
S SS R S SRS + S SPSP+ + K K P+
Sbjct: 180 P------SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK---------KEKTPELP 224
Query: 148 EKERKRRSPS-------------PKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPV 194
E K + PS PKP + K+ E S K K P
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIP-------EPKEPSPEKNSKKEKEKEKTRPR 277
Query: 195 ERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPR 254
R SK + +P +H + + +P RP PRR +PPR
Sbjct: 278 SRSR---SKSRSRTRSRSPSHTRPRRRHRSRSR----SYSPRRRPSPRRRPSPRRRTPPR 330
Query: 255 RMLPPPPMWR--RSPPRMRRR-----------SRSPRRRSPVR---RRSRSPGRRRHRSR 298
RM PPPP R RSP R RRR S S R RSP + +R+ SP R+ R
Sbjct: 331 RM-PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLS 389
Query: 299 SSSNSSR 305
S++ R
Sbjct: 390 PSASPPR 396
Score = 66.6 bits (161), Expect = 3e-11
Identities = 94/341 (27%), Positives = 127/341 (37%), Gaps = 79/341 (23%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKD----------RSKDKGATKESSEKDRGRDKTRK 64
K+ +K TR S ++ K RS +S+ RS+ + + R R R+
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR 325
Query: 65 RRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS---- 120
R R R S + S+ S SGSSSSS+SSRS S +SS
Sbjct: 326 RTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385
Query: 121 ---SGSPSPSRRRH--------------------DNRRRSRSKSKPPKRDE--------- 148
S S SP RRRH NR R S P R
Sbjct: 386 RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445
Query: 149 KERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMH----PHLSKG 204
++R+ SP+PKP KV + + GK+ D +R S
Sbjct: 446 EKRESPSPAPKPRKVELSESEEDKG-----------GKMAAADSVQQRRQYRRQNQQSSS 494
Query: 205 YAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA-PWPRPPPRRFSPPRRMLPPPPMW 263
+ + DE K H+ G++ + + + A P PR + SP R P
Sbjct: 495 DSGSSSSSEDERPKR-SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP--- 550
Query: 264 RRSPPRMRRRSRSP-------RRRSPV---RRRSRSPGRRR 294
SPP RRR RSP RRR+P RRR+ SP RR
Sbjct: 551 --SPPPTRRR-RSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
Score = 55.5 bits (132), Expect = 6e-08
Identities = 67/319 (21%), Positives = 118/319 (36%), Gaps = 39/319 (12%)
Query: 6 VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD----K 61
++++ L +K+ ++ R K + S + ++RS+ K S R R +
Sbjct: 136 IEQEKLASMKKQDEDKDKR----DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRR 191
Query: 62 TRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
RKR + S T+SRS S + + S S ++STS
Sbjct: 192 ERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPE 251
Query: 122 GSP---SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIM 178
P PS ++ + + + K++P R + + R+ S P+ R R+ ++ +
Sbjct: 252 PIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP 311
Query: 179 EIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKA-----LKHMDGGQIDGQEI 233
P R P + P ++ + + G
Sbjct: 312 R-----------RRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
Query: 234 TATAVLAPWPRPPPRRFSPPRRMLPPPPMWRR-----SPPRMRRRSRSPRRRSPVRRRSR 288
++++ + R PP++ PP+R PP RR SPPR R R P P R S
Sbjct: 361 SSSSSRS---RSPPKK--PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSP 415
Query: 289 SP--GRRRHRSRSSSNSSR 305
+P R +SR S + R
Sbjct: 416 TPQQSNRTRKSRVSVSPGR 434
Score = 54.7 bits (130), Expect = 1e-07
Identities = 84/327 (25%), Positives = 114/327 (34%), Gaps = 87/327 (26%)
Query: 16 ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSST 75
+ +K + +P+P RK E +D+ A D ++RR
Sbjct: 443 KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA----------DSVQQRRQYR------ 486
Query: 76 RSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNR- 134
R S+S SGSS+S+ S + G R S S S SPSP +R+ +
Sbjct: 487 RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR----RRRHSPSRSASPSPRKRQKETSP 542
Query: 135 --RRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDM 192
RR RS S PP R +RRSPSP P R R T + +
Sbjct: 543 RGRRRRSPSPPPTR-----RRRSPSPAPPP----RRRRTPTPPP---------RRRTPSP 584
Query: 193 PVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPW----PRPPPR 248
P R P +P ++ + TA+ P P PPP+
Sbjct: 585 PPRRRSP------------SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
Query: 249 R---FSPPRRMLPPPPMWRRSPPRM----------------------RRRSRSPRRRSPV 283
R SPP + P RRSP +R S SPR R+P
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
Query: 284 RRRSRSPGRR-----RHRSRSSSNSSR 305
S P RR R +S S S+R
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSPSPSTR 719
Score = 52.4 bits (124), Expect = 5e-07
Identities = 83/332 (25%), Positives = 111/332 (33%), Gaps = 50/332 (15%)
Query: 10 SLLGVKENNKKSSTRAP--SPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRS 67
SL G ++ S +R+P P KR K++ S + K R
Sbjct: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
Query: 68 ASSGSSSTRSRSSSTSSSGSSTS------TGSSSGSSSSSASS-RSGSSSTSRSSSSSSS 120
+ + S R+R S S S TS G+ S S A R S S
Sbjct: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEI 180
+ + S +RR R+ +S S E +R PK + V G + R
Sbjct: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER----PKRSHVKNGEVGRRRRHSPSRSA 529
Query: 181 FSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLA 240
+ K + P R S P + +
Sbjct: 530 SPSPRKRQKETSPRGRRRRSPS----------PPPTRRRRSPSPAPPPRRRRTPTPPPRR 579
Query: 241 PWPRPPPRRFSP-PRRMLPP--------PPMWRR--------------SPPRMRRRSRSP 277
P PPPRR SP PRR PP PP RR SPP RR S SP
Sbjct: 580 RTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSP 639
Query: 278 ---RRRSPV-RRRSRSPGRRRHRSRSSSNSSR 305
+R SPV +RRS S + + S S S+R
Sbjct: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTR 671
Score = 48.9 bits (115), Expect = 6e-06
Identities = 74/298 (24%), Positives = 105/298 (35%), Gaps = 77/298 (25%)
Query: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRS 67
K +G + + S + +PSP KR+ + + + R + TR+RRS
Sbjct: 513 KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR------------RSPSPPPTRRRRS 560
Query: 68 ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPS 127
S R R+ + + S R S S R S SPSP
Sbjct: 561 PSPAPPPRRRRTPTPPPR-----------RRTPSPPPRRRSPSPRRYSPPIQRRYSPSP- 608
Query: 128 RRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKI 187
+RR+ S PPKR R SPSP P + R++ +
Sbjct: 609 ----PPKRRTASPPPPPKR------RASPSPPPKR----RVSHSPPP------------- 641
Query: 188 KMIDMPV-ERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPR-- 244
K PV +R P LS KH G + +P P
Sbjct: 642 KQRSSPVTKRRSPSLSS-----------------KHRKG---SSPSRSTREARSPQPNKR 681
Query: 245 --PPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSS 300
P PR +P PPP S RR+S SP R P+RR SR+P ++ + +S
Sbjct: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTR-PIRRVSRTPEPKKIKKAAS 738
Score = 46.2 bits (108), Expect = 4e-05
Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 11/216 (5%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSS 81
++ +P P +R S + R +T+ R + + +++AS S R SSS
Sbjct: 693 TSSSPPPVRRGASSSPQR--RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 750
Query: 82 TSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS---SSSSSSSGSPSPSR---RRHDNRR 135
S SGS + S S+S S++ S + + S + SPSP R + ++
Sbjct: 751 RSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKK 810
Query: 136 RSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVE 195
+ + K K K+D+K +K + K K VT I +T + + + P
Sbjct: 811 KKKKKDKKHKKDKKHKKHK--KHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
Query: 196 RMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQ 231
+ S+ ++ EKAL+ M Q+ Q
Sbjct: 869 KKETE-SEAEDNLDDLEKHLREKALRSMRKAQVSPQ 903
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/148 (31%), Positives = 62/148 (41%), Gaps = 17/148 (11%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSE---KDRGRDKTRKRRSASSGSSST 75
K+ + P P KR+ K R K+ S K R + K R SS S ST
Sbjct: 611 KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670
Query: 76 R-SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNR 134
R +RS + S + + +SSS R G +SSS SPSPS R
Sbjct: 671 REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG------ASSSPQRRQSPSPSTR----P 720
Query: 135 RRSRSKSKPPKRDEKERKRRSPSPKPTK 162
R S++ PK K +K SPSP+ +
Sbjct: 721 IRRVSRTPEPK---KIKKAASPSPQSVR 745
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/179 (25%), Positives = 69/179 (38%), Gaps = 35/179 (19%)
Query: 19 KKSSTRAPSPTKR-------KDRSDEKSKDRSKDKGAT-KESSEKDRGRDKTRKRRSASS 70
K+ ++ +P P +R K RS +K RS + ++ S R + R +
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR 681
Query: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS----------------------GS 108
S S R R+ TSSS G+SS + S S
Sbjct: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 741
Query: 109 SSTSRSSSSSSSSGSPSPSRRRHDN-----RRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
S R SSS S SGSP P+ ++ + +S S + P K+ K +PSP P +
Sbjct: 742 QSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800
Score = 31.2 bits (69), Expect = 1.2
Identities = 17/70 (24%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 19 KKSSTRAPSPTKRKDRSDE---KSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSST 75
KK+ + PSP+ ++ E K K + KDK K+ K + K K +A++ ++ T
Sbjct: 787 KKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVT 846
Query: 76 RSRSSSTSSS 85
+ ++ +++
Sbjct: 847 PAAIAAATTT 856
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 70.5 bits (171), Expect = 2e-12
Identities = 72/240 (30%), Positives = 105/240 (43%), Gaps = 30/240 (12%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKD----------RGRDKTRK---RRSA 68
++R+ SP R D D + + R++++ +D RGR R RS
Sbjct: 185 ASRSRSPN-RFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRGRRPERNYQHSRSR 243
Query: 69 SSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSR 128
S SS +R++S +S +S T S SGS S S SS S S S SSSS+SS S S S
Sbjct: 244 SPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSIS---SSSSTSSDSSDSSSS 300
Query: 129 RRHDNRRRSRSKSKPPKRD-------EKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIF 181
D+ RS + P EK+ R+S K + + R T KD + F
Sbjct: 301 SSDDSPARSVQSAAVPAPTSQLLSSLEKDEPRKSFGIKVQNLPV-RSTDTSLKDGLFHEF 359
Query: 182 STYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAP 241
+GK+ + ++H + Y V F ++ EKAL G G +I TA + P
Sbjct: 360 KKFGKVTSV-----QIHGTSEERYGLVFFRQQEDQEKALTASKGKLFFGMQIEVTAWIGP 414
Score = 37.0 bits (84), Expect = 0.022
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 17/134 (12%)
Query: 42 RSKDKGATKESSEKDRGRDKTRK-----------RRSASSGSSSTRS-RSSSTSSSGSST 89
R +++ +E E DR RD R+ RR S G+S +++ R S S +
Sbjct: 698 RQRERERERERFESDRDRDHERRPIERSQSPVHLRRPQSPGASPSQAERLPSDSERRLYS 757
Query: 90 STGSSSGSSSSSASSRSGSSSTSR-----SSSSSSSSGSPSPSRRRHDNRRRSRSKSKPP 144
+ SGS SS + R SR + + + P R + R + K +
Sbjct: 758 RSSDRSGSCSSLSPPRYEKLDKSRLERYTKNEKTDKERTFDPERVERERRLIRKEKVEKD 817
Query: 145 KRDEKERKRRSPSP 158
K D+++RK + SP
Sbjct: 818 KTDKQKRKGKVHSP 831
Score = 36.2 bits (82), Expect = 0.037
Identities = 62/272 (22%), Positives = 98/272 (36%), Gaps = 80/272 (29%)
Query: 30 KRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSAS--------------SGSSST 75
+R +R+ + S+ RS ++ S + +R RS S S SSST
Sbjct: 231 RRPERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSISSSSST 290
Query: 76 RSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTS-----------------RSSSSS 118
S SS +SSS S S S S++ A + SS RS+ +S
Sbjct: 291 SSDSSDSSSSSSDDSPARSVQSAAVPAPTSQLLSSLEKDEPRKSFGIKVQNLPVRSTDTS 350
Query: 119 SSSG-----------------SPSPSR------RRHDNRRRSRSKSK------------- 142
G S R R+ +++ ++ + SK
Sbjct: 351 LKDGLFHEFKKFGKVTSVQIHGTSEERYGLVFFRQQEDQEKALTASKGKLFFGMQIEVTA 410
Query: 143 ---PPKRDEKERKRRSPS-----PKPTK-VHIGRLTRNVTKDHIMEIFSTYGKIKMIDMP 193
P E E + PK T+ + IG L + T + IF +G+I ID+
Sbjct: 411 WIGPETESENEFRPLDERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIK 470
Query: 194 VERMHPHLSKGYAYVEFENPDEAEKALKHMDG 225
P YA++++ + KA+K MDG
Sbjct: 471 KVNGVPQ----YAFLQYCDIASVCKAIKKMDG 498
Score = 34.3 bits (77), Expect = 0.14
Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 14/116 (12%)
Query: 50 KESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS 109
+E S + R R++ R+R + R R S S S G+S S A S
Sbjct: 693 REYSYRQRERERERERFESDRDRDHER-RPIERSQSPVHLRRPQSPGASPSQAERLPSDS 751
Query: 110 ST---SRSSSSSSSSGSPSPSR----------RRHDNRRRSRSKSKPPKRDEKERK 152
SRSS S S S SP R R N + + ++ P+R E+ER+
Sbjct: 752 ERRLYSRSSDRSGSCSSLSPPRYEKLDKSRLERYTKNEKTDKERTFDPERVERERR 807
Score = 32.7 bits (73), Expect = 0.41
Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 21/161 (13%)
Query: 19 KKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT----------RKRRSA 68
+ +T P S + K ++ G+ ++ KD G DK K+ +
Sbjct: 2010 RPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAP 2069
Query: 69 SSGSSSTRSRS--SSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
S S R RS S + S++ + S A++++G + + S S SP
Sbjct: 2070 EKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAGERESGVVAVSPEKSESP-- 2127
Query: 127 SRRRHDNRRRSRSKSKPPKRDEKERKR----RSPSPKPTKV 163
+ ++ S+ KS P D++ K PSP+ T++
Sbjct: 2128 ---QKEDGLSSQLKSDPVDPDKEPEKEDVSASGPSPEATQL 2165
Score = 31.6 bits (70), Expect = 0.91
Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 265 RSPPRMRRRSRSPRR-RSPVRRRSRSPGRRRHRSRSSSNSS 304
RSP + R++SP+R S R +RSP RSRSSS+ S
Sbjct: 243 RSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDS 283
Score = 30.0 bits (66), Expect = 2.7
Identities = 28/148 (18%), Positives = 57/148 (38%), Gaps = 15/148 (10%)
Query: 21 SSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80
++ R P K + R+DE+ ++ +K+ T + E G R +++A+ G
Sbjct: 1946 TTPRRGRPPKTRRRADEEEENEAKEPAETLKPPE---GWRSPRSQKTAAGG--------- 1993
Query: 81 STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140
G ++ A++ G + SS + + +R+ + +
Sbjct: 1994 --GPQGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTD 2051
Query: 141 SKPPKRDEKERKRRSPSP-KPTKVHIGR 167
PP+ E + P+P K +K GR
Sbjct: 2052 KNPPETAPVEVVEKKPAPEKNSKSKRGR 2079
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 69.3 bits (168), Expect = 4e-12
Identities = 72/281 (25%), Positives = 116/281 (41%), Gaps = 37/281 (13%)
Query: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRS 79
+ +R+ SP K +D S +S +++D+ S ++ RD +R R S + RSRS
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARDR---SRSRSPNKARDHSRSR---SPNKARDRSRS 476
Query: 80 SSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSS------SGSPSPSRRRHD- 132
S S + GS S S R S SSS S SPS R+R
Sbjct: 477 RSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 133 ---NRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKM 189
N+ R RS+S+ P + + R+ RSPS + + R R+ +K+ E + +
Sbjct: 537 RSPNKERDRSQSRSPSEEREHRQSRSPSKERDR----RRWRSPSKER--ERRQSRSSSEE 590
Query: 190 IDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRR 249
D R P+ GY+ + ++A + Q T++ +
Sbjct: 591 RDHSRSR-SPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSS-----------KE 638
Query: 250 FSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSP 290
P + +P P W+RSP R S++ R+P + S SP
Sbjct: 639 SDPSQSTVPRSPDWKRSPTRTSSLSQN---RTPSKTSSHSP 676
Score = 65.9 bits (159), Expect = 4e-11
Identities = 82/325 (25%), Positives = 126/325 (38%), Gaps = 37/325 (11%)
Query: 14 VKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-----DRGRDKTRK---- 64
VK N+ +STR+ + + RS +S+ S+ + ++ S R R +TRK
Sbjct: 266 VKSYNQ-ASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILS 324
Query: 65 -------RRSASSGSSSTRSRSS----STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSR 113
RS S G S +SR+ S + S + + S S S SSS SS+ R
Sbjct: 325 QMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR 384
Query: 114 SSSSSSSSGSPSP----SRRRHDNRRRSRSKSKPPKRDEKERKRRSP----------SPK 159
S S SGSP+ SR R N+ R RS+S+ P + + RSP SP
Sbjct: 385 KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPY 444
Query: 160 PTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENP-DEAEK 218
+ + N +DH + + + H G E ++ +
Sbjct: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
Query: 219 ALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPR 278
+ + +E +P R+ P + S R R+SRSP
Sbjct: 505 KERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPS 564
Query: 279 RRSPVRRRSRSPGRRRHRSRSSSNS 303
+ RRR RSP + R R +S S+S
Sbjct: 565 KERD-RRRWRSPSKERERRQSRSSS 588
Score = 56.2 bits (134), Expect = 3e-08
Identities = 86/331 (25%), Positives = 129/331 (38%), Gaps = 57/331 (17%)
Query: 4 SGVKKKSLLGVKENN-KKSSTRAPSPTKRKDRSD--EKSKDRSKDKGATKESSEKDR-GR 59
SG +K++ V+ ++ K++ +RA S T++ S S+ RS KG ++ S R GR
Sbjct: 292 SGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGR 351
Query: 60 DKT-----RKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSAS-SRSGSSSTSR 113
K RS S SS++ R SSS S S SGS + SRS S + +R
Sbjct: 352 SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKAR 411
Query: 114 SSSSSSS-------SGSPSPSRRRHDNRRRS------RSKSKPPKRDEKERKRRSP---- 156
S S S S S SP++ R +R RS RS+S+ P + + RSP
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR 471
Query: 157 ------SPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEF 210
SP + H + + +DH + P + S+ +
Sbjct: 472 DRSRSRSPSKERDHSQLGSPSKERDH-----------RRSRSPSKERQCRQSRSSSKERD 520
Query: 211 ENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRM 270
+ + + +E + +P R+ P S R
Sbjct: 521 HRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP------------SKERD 568
Query: 271 RRRSRSPRRRSPVRRRSRSPGRRRHRSRSSS 301
RRR RSP + RR+SRS R SRS S
Sbjct: 569 RRRWRSPSKERE-RRQSRSSSEERDHSRSRS 598
Score = 55.5 bits (132), Expect = 6e-08
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 15/162 (9%)
Query: 17 NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-----DRGRDKTRKRRSASSG 71
+ ++ R+ SP+K + R +S ++ +D+ ++ SE+ R K R RR S
Sbjct: 516 SKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSP 575
Query: 72 SSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRH 131
S R S +SS S S S + +SG S SS + S S +PS+ +
Sbjct: 576 SKERERRQSRSSSE-------ERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGN 628
Query: 132 DNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVT 173
++ R+ SK P + RSP K + L++N T
Sbjct: 629 HSQSRTSSKESDPSQSTVP---RSPDWKRSPTRTSSLSQNRT 667
Score = 49.7 bits (117), Expect = 3e-06
Identities = 80/318 (25%), Positives = 110/318 (34%), Gaps = 57/318 (17%)
Query: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRS-KDKGATKESSEKDRGRDKT 62
SG+ + S L V + K T P+K K + S R K G S +
Sbjct: 202 SGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTE 261
Query: 63 RKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSS-ASSRSGSSSTSRSSSSSSS- 120
R S +STRSR S S S S + S S + S S S + SR+ S +
Sbjct: 262 MSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 121 --SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIM 178
S S+ R ++ +S+++S+ P+R R+PS
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSK-------------------- 361
Query: 179 EIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAV 238
ER H H + K G + Q + +
Sbjct: 362 ----------------ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSR 405
Query: 239 LAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMR--RRSRSP-------RRRSPVR----R 285
R R SP + RSP + R RSRSP R RSP +
Sbjct: 406 SPNKARDRSRSRSPYKAR---DRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHS 462
Query: 286 RSRSPGRRRHRSRSSSNS 303
RSRSP + R RSRS S S
Sbjct: 463 RSRSPNKARDRSRSRSPS 480
Score = 47.4 bits (111), Expect = 2e-05
Identities = 69/313 (22%), Positives = 119/313 (38%), Gaps = 35/313 (11%)
Query: 23 TRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGS---------S 73
+R +P +R RS ++S R+ G + + + R S GS +
Sbjct: 119 SRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRT 178
Query: 74 STRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS-------SSSSSSSGSPSP 126
S R RS S + S S GS +S + + ST++ S S + SPS
Sbjct: 179 SNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSS 238
Query: 127 SRRRHDNRRR---SRSKSKPP--------------KRDEKERKRRSPSPKPTKVHIGRLT 169
SR+ + SR KS P R + +S SP+ ++ + T
Sbjct: 239 SRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRT 298
Query: 170 RNVTKDHIMEIFSTYGKIKMIDMPVERMHPH-LSKGYAYVEFENPDEAEKALKHMDGGQI 228
+ + H + + + + + +M H S+ ++ + +N + + + +
Sbjct: 299 HSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRN 358
Query: 229 DGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSR 288
+E + + + R S PR+ + R RSRSP + R RSR
Sbjct: 359 PSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD-RSRSR 417
Query: 289 SPGRRRHRSRSSS 301
SP + R RSRS S
Sbjct: 418 SPYKARDRSRSRS 430
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 2/148 (1%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSS 74
K ++K S + APS + + K AT S +R + S S S
Sbjct: 5 KRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKS 64
Query: 75 TRSRSSSTSSSG--SSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHD 132
T+S S+ + S SS S S + S S+ + +S S++S + SR R
Sbjct: 65 TKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTP 124
Query: 133 NRRRSRSKSKPPKRDEKERKRRSPSPKP 160
RR SRS + P R + R+ +P
Sbjct: 125 GRRGSRSSKRSPSRASTPGRIRTHGARP 152
Score = 40.4 bits (93), Expect = 0.002
Identities = 78/338 (23%), Positives = 129/338 (38%), Gaps = 40/338 (11%)
Query: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKR-KDRSDEKSKDRSKDKGATKESSEKDRGRDKT 62
S +SL+ K ++S +PS +K K S +++ + S + R T
Sbjct: 37 SATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVST 96
Query: 63 RKRRSASSGSSSTR--------SRSSSTSSSGSSTSTGSSSGSSSSSA----SSRSGSSS 110
R S +S +S R SR + GS +S S S +S+ +R G +S
Sbjct: 97 DTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMAS 156
Query: 111 TSRS-SSSSSSSGSPSPSRRRHDNRRRSRSKS--------KPPKRDEKERKRR---SPS- 157
R+ +S S S R R NR RS S+ +PP R +PS
Sbjct: 157 RVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPST 216
Query: 158 ---PKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLS---KGYAYVEFE 211
PT + + N + ++ +YG++ + +S K Y
Sbjct: 217 AKCQTPTGIPSKEKSDNPSPSSSRKV-KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275
Query: 212 NPDEAEKALKHMDGGQIDGQEITATAVLA-PWPRPPPRRFSPPRRMLPPPPMWRRSPPRM 270
+ ++ + + Q+ T + V + W R R S R+ + M R S R
Sbjct: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI-LSQMGRHSQSRS 334
Query: 271 RRRSRSPRR-RSPVRRR----SRSPGRRRHRSRSSSNS 303
+ +S + R+P R R SR+P + R S S S+S
Sbjct: 335 HSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS 372
Score = 39.7 bits (91), Expect = 0.003
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 17 NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRR-SASSGSSST 75
+ +K+ +R+ +P+K + S ++ + D + D R TR S + S T
Sbjct: 612 SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKT 671
Query: 76 RSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSS 119
S S ST SG T S S + A++ + RSSSSSS
Sbjct: 672 SSHSPSTFPSGGQTL---SQDDSQADATTSKATLPGERSSSSSS 712
Score = 38.5 bits (88), Expect = 0.007
Identities = 41/144 (28%), Positives = 60/144 (41%), Gaps = 15/144 (10%)
Query: 22 STRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSS 81
ST++ +P +RS +K + SS K T KR ++ SS +R RS +
Sbjct: 34 STKSATP----NRSLVPTKPATSRNSVMSPSSSKSTKSTST-KRAPSNRPSSRSRVRSKA 88
Query: 82 TSSSGSSTSTGSSSGSSSSSAS--SRSGSSST--------SRSSSSSSSSGSPSPSRRRH 131
+ S ST T +S S +S R G+ S SRSS S S S R H
Sbjct: 89 RTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTH 148
Query: 132 DNRRRSRSKSKPPKRDEKERKRRS 155
R S+ + P +K + +S
Sbjct: 149 GARPGMASRVRTPTSQQKGSRGKS 172
Score = 37.0 bits (84), Expect = 0.022
Identities = 35/107 (32%), Positives = 47/107 (43%), Gaps = 6/107 (5%)
Query: 21 SSTRAPSPTKRKDRSDEKSKD--RSKDKGATKES--SEKDRGRDKTRKRRSASSGSSSTR 76
S RA S K RS SK+ S+ + ++KES S+ R KR + S S
Sbjct: 606 SRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQN 665
Query: 77 SRSSSTSSSGSST--STGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
S TSS ST S G + S A + + ++ SSSSSS
Sbjct: 666 RTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 34.3 bits (77), Expect = 0.14
Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 18/135 (13%)
Query: 17 NNKKSSTRAPSPTKR------KDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASS 70
+ ++ +R+ SP K+ + S EK+ RS+ S E + + +T + S S
Sbjct: 588 SEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR-----TPSKEGNHSQSRTSSKESDPS 642
Query: 71 GSSSTRS---RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPS 127
S+ RS + S T +S S + S SS S ++ SG + S+ S + + + S
Sbjct: 643 QSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADA----TTS 698
Query: 128 RRRHDNRRRSRSKSK 142
+ R S S SK
Sbjct: 699 KATLPGERSSSSSSK 713
Score = 32.7 bits (73), Expect = 0.41
Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 7/104 (6%)
Query: 74 STRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSST-------SRSSSSSSSSGSPSP 126
S+ RSS S S + + + + AS +S S+T ++ ++S +S SPS
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 127 SRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTR 170
S+ + ++P R K R+PS T + ++
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASK 105
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 68.9 bits (167), Expect = 5e-12
Identities = 48/109 (44%), Positives = 62/109 (56%), Gaps = 10/109 (9%)
Query: 64 KRRSASSGSSSTRS--RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
+R+ +G RS SSS+SSS SS+S+ SSS SSSSS+SS S SSS+S SSSSSSS+
Sbjct: 132 RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191
Query: 122 GSPSPSRRRHDNR-------RRSRSKSKPPKRD-EKERKRRSPSPKPTK 162
P + +++ R +S K P RD K K S PK K
Sbjct: 192 SFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
Score = 63.2 bits (152), Expect = 3e-10
Identities = 45/116 (38%), Positives = 58/116 (50%), Gaps = 22/116 (18%)
Query: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSP 126
S+SS SSS+ S SSS+SSS SS+S+ SSS SSSSS+SS S +S + PS
Sbjct: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209
Query: 127 SRRRH---------DNRRRSRSKSKPPKRDE-------------KERKRRSPSPKP 160
R H D+ + S+ SK PK ++ KE K S PKP
Sbjct: 210 DSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP 265
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/78 (35%), Positives = 36/78 (46%)
Query: 99 SSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSP 158
+SS+SS S SSS+S SSSSSSSS S S S + S S S + K K P
Sbjct: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207
Query: 159 KPTKVHIGRLTRNVTKDH 176
+ ++DH
Sbjct: 208 SKDSREHKSAFKEPSRDH 225
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)
Query: 27 SPTKRKDRSDEKSKDRSKDKGATKE----------------SSEKDRGRDKTRKRRSASS 70
+P+KR SD + K K ++ E S++K + +DK+ +
Sbjct: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339
Query: 71 GSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
S T + ST + S + SS+S S S +SSSSSSS S +PS+ R
Sbjct: 340 IESETSEKKKSTLPPFDDIVDPNDS-DVEENISSKSDSEQPSPASSSSSSSSSFTPSQTR 398
Query: 131 HDNRRRSRSKSKPPKRDEKE 150
RS K +E+E
Sbjct: 399 QQGPLRSIMKDLHSDDNEEE 418
Score = 28.9 bits (63), Expect = 5.9
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 5/159 (3%)
Query: 2 DLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDK-GATKESSEKDRGRD 60
+LS K+K E KS + AP ++ KD+S K G K SE +
Sbjct: 292 ELSAKKRKK--SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKK 349
Query: 61 KTRKRRS--ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
T S SS S S + SSS SSSS S++ RS
Sbjct: 350 STLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKD 409
Query: 119 SSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
S ++ +P R +R S S
Sbjct: 410 LHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLS 448
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 68.9 bits (167), Expect = 5e-12
Identities = 84/300 (28%), Positives = 117/300 (39%), Gaps = 31/300 (10%)
Query: 15 KENNKKSSTRAPSPTKRKD---RSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSG 71
+ ++ +SS+R+ S ++R RS ++ RS+ ++ S + R ++R RR + G
Sbjct: 388 RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRR-YSRSRSRGRRHSGGG 446
Query: 72 SSSTRSRSSSTSSSGS-STSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRR 130
S S S + G S S S S R G SSS S SS S SPSR R
Sbjct: 447 SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSR 506
Query: 131 HDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIF--------S 182
R RS S S R + +SPSP P + +LTR + E
Sbjct: 507 SLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAR---EKLTRPAASPAVGEKLKKTEPAAGK 563
Query: 183 TYGKIKMIDMPVERMHPHLSKGY-AYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAP 241
G K P E++ + K + + EK ++ Q E+ A A
Sbjct: 564 ETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMA---- 619
Query: 242 WPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSS 301
R R W R + R+SRSP SP R S RRR RSRS S
Sbjct: 620 ----RKIRMKERERREKEREEWER---QYSRQSRSP---SPRYSREYSSSRRRSRSRSRS 669
Score = 50.4 bits (119), Expect = 2e-06
Identities = 74/296 (25%), Positives = 117/296 (39%), Gaps = 38/296 (12%)
Query: 7 KKKSLLGVKENNKKSSTRAPSPTK---RKDRSDEKSKDRSKDKGATKESSEKDR------ 57
++K L G ++ + S R SPT ++ S+ S+ RS+ + T EK
Sbjct: 275 REKRLRG-RKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFG 333
Query: 58 GRDKTRKRRSASSGSS--STRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSS 115
G D+ +A++ +S +T + G + +S+ SSS+SS S +S TS S
Sbjct: 334 GSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR 393
Query: 116 SSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKD 175
SSS SS + + R +RS+S+ R +R S S + H G +R+ +
Sbjct: 394 SSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHR- 452
Query: 176 HIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITA 235
+S + P R G Y + L+H ++
Sbjct: 453 -----YSRSPARRGGYGPRRRSRSRSHSGDRY------RRGGRGLRHH----------SS 491
Query: 236 TAVLAPWPRPPPRRFSPPR-RMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSP 290
+ + W P R S R R P P RS R R +S SP SP R + P
Sbjct: 492 SRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSP---SPAREKLTRP 544
Score = 46.2 bits (108), Expect = 4e-05
Identities = 64/259 (24%), Positives = 89/259 (34%), Gaps = 50/259 (19%)
Query: 65 RRSASSGSSSTRSRSSSTSSSGSS-----TSTGSSSGSSSSSASSRSGSSSTSRSSSSSS 119
+RS S SS +RSRS S + TS G S ++++A++ + S T+ +
Sbjct: 301 KRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPP 360
Query: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
G P+P R RRRS S S R S G R+ H
Sbjct: 361 QPGGPAPGRNA-SARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGR--HARS 417
Query: 180 IFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVL 239
++ + + R + +H GG DG
Sbjct: 418 RSRSWSRSRSRSRRYSRSR------------------SRGRRHSGGGSRDGHR------- 452
Query: 240 APWPRPPPRR--FSPPRRMLPPP---PMWRRSPPRMRRRSRS----------PRRRSPVR 284
+ R P RR + P RR +RR +R S S R RS R
Sbjct: 453 --YSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTR 510
Query: 285 RRSRSPGRRRHRSRSSSNS 303
RS SP + RSRS S S
Sbjct: 511 SRSHSPSPSQSRSRSRSRS 529
Score = 45.1 bits (105), Expect = 8e-05
Identities = 78/332 (23%), Positives = 110/332 (33%), Gaps = 76/332 (22%)
Query: 14 VKENNKKSST--RAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR------ 65
V + NK+++T A R R D++ + K A +E GR R+R
Sbjct: 218 VADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREK 277
Query: 66 ------------------------RSASSGSSSTRSRSSSTSSSGSS-----TSTGSSSG 96
RS S SS +RSRS S + TS G S
Sbjct: 278 RLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDE 337
Query: 97 SSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSP 156
++++A++ + S T+ + G P+P R RRRS S S R S
Sbjct: 338 EAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNA-SARRRSSSSSSSSSASRTSSSRSSS 396
Query: 157 SPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEA 216
G R + H ++ + + R
Sbjct: 397 RSSSRSRRGGGYYR--SGRHARSRSRSWSRSRSRSRRYSR------------------SR 436
Query: 217 EKALKHMDGGQIDGQEITATAVLAPWPRPPPRR--FSPPRRMLPPPPMWRRSPPRMRRRS 274
+ +H GG DG + R P RR + P RR S R RR
Sbjct: 437 SRGRRHSGGGSRDGHR---------YSRSPARRGGYGPRRRSRSR----SHSGDRYRRGG 483
Query: 275 RSPRRRSPVRRRSR---SPGRRRHRSRSSSNS 303
R R S R RS SP R R +RS S+S
Sbjct: 484 RGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHS 515
Score = 30.4 bits (67), Expect = 2.0
Identities = 16/32 (50%), Positives = 19/32 (59%)
Query: 113 RSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPP 144
R S S S SP SR +RRRSRS+S+ P
Sbjct: 639 RQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 68.6 bits (166), Expect = 7e-12
Identities = 49/141 (34%), Positives = 67/141 (47%), Gaps = 4/141 (2%)
Query: 165 IGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMD 224
+ LT + D + +F YG++ + +P E H +G+A+V F + +A+ A MD
Sbjct: 18 VDNLTYRTSPDSLRRVFEKYGRVGDVYIPREP-HTKAPRGFAFVRFHDRRDAQDAEAAMD 76
Query: 225 GGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVR 284
G ++DG+E+ P R PR RRS RRSRSPRRR R
Sbjct: 77 GAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRS-RSYGRRSRSPRRRH--R 133
Query: 285 RRSRSPGRRRHRSRSSSNSSR 305
RSR P R RSRS SR
Sbjct: 134 SRSRGPSCSRSRSRSRYRGSR 154
Score = 62.8 bits (151), Expect = 4e-10
Identities = 57/151 (37%), Positives = 77/151 (50%), Gaps = 16/151 (10%)
Query: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD---KTRKRRS-------AS 69
+S +R PS ++ + RS + S+ + S R ++R R S +S
Sbjct: 133 RSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSS 192
Query: 70 SGSSSTR----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS 125
SG S++R S S S SGSSTS+ S+S S SSSA RS SSS SRS S S SS
Sbjct: 193 SGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSAR-RSKSSSVSRSRSRSRSSSMTR 251
Query: 126 PSRRRHDNRRRSRSKSK-PPKRDEKERKRRS 155
R + +SRS+SK PPK E+E + S
Sbjct: 252 SPPRVSKRKSKSRSRSKRPPKSPEEEGQMSS 282
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/162 (34%), Positives = 81/162 (50%), Gaps = 14/162 (8%)
Query: 13 GVKENNKKSSTRAPSPTKR-----KDRSDEKSKDRSKDKGATKESSEKDRGR-DKTRKRR 66
G ++ R+ SP +R + S +S+ RS+ +G+ S R ++R R
Sbjct: 113 GYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSR 172
Query: 67 SASSGSSSTRSR--SSSTSSSGSSTST----GSSSGSSSSSASSRSGSSSTSRSSSSSSS 120
S S S SR S SSSG S S SS S S +S+ S S+STS+SSS+ S
Sbjct: 173 SPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRS 232
Query: 121 SGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
S S SR R +R S ++S PP+ +++ K RS S +P K
Sbjct: 233 KSS-SVSRSRSRSRSSSMTRS-PPRVSKRKSKSRSRSKRPPK 272
Score = 31.2 bits (69), Expect = 1.2
Identities = 63/258 (24%), Positives = 83/258 (32%), Gaps = 47/258 (18%)
Query: 33 DRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTG 92
DR D + + + D GA + E + +R S R RS S S G
Sbjct: 64 DRRDAQDAEAAMD-GAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYG 122
Query: 93 SSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERK 152
S S SRS S SRS S S GS R SRS P R R
Sbjct: 123 RRSRSPRRRHRSRSRGPSCSRSRSRSRYRGS-----------RYSRS---PYSRSPYSRS 168
Query: 153 RRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFEN 212
R S SP Y + + + H + S GY+ +
Sbjct: 169 RYSRSP-------------------------YSRSRYRESRYGGSH-YSSSGYSNSRY-- 200
Query: 213 PDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRR 272
+ H G +T+ + R S R M RSPPR+ +
Sbjct: 201 -SRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSM-TRSPPRVSK 258
Query: 273 RSRSPRRRSPVRRRSRSP 290
R R RS +R +SP
Sbjct: 259 RKSKSRSRS--KRPPKSP 274
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 68.6 bits (166), Expect = 7e-12
Identities = 62/175 (35%), Positives = 78/175 (44%), Gaps = 20/175 (11%)
Query: 2 DLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKS-KDRSKDKGATK-ESSEKDRGR 59
D G K +S KE + S S +K +S+E + K+ S DKG + SSE R
Sbjct: 55 DNEGRKHRSRSRSKEGRRHESKDKSS---KKHKSEEHNDKEHSSDKGRERLNSSENGEDR 111
Query: 60 DKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS----SSTSRSS 115
K RK R +S G S +RSRS S S S SRS S S SRS
Sbjct: 112 HK-RKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Query: 116 SSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKER----------KRRSPSPKP 160
S S SR RH +R RSRS+++ RD K+R R+PSP P
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPP 225
Score = 58.2 bits (139), Expect = 9e-09
Identities = 47/169 (27%), Positives = 73/169 (43%), Gaps = 11/169 (6%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSS- 73
K +N+ R+ S +K R + SKD+S K ++E ++K+ DK R+R ++S
Sbjct: 53 KSDNEGRKHRSRSRSKEGRRHE--SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED 110
Query: 74 --------STRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPS 125
S+R RS S S S S S + SR S SRS S
Sbjct: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Query: 126 PSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174
+RR +R RSRS+ + R + RS K R +R++++
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 219
Score = 57.8 bits (138), Expect = 1e-08
Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 3/158 (1%)
Query: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDK-GATKESSEKDRGRDKTRKRRSASSGSS 73
K + +S +R+ ++ D K + RS+ K G ES +K + K+ + S
Sbjct: 37 KHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSD 96
Query: 74 STRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDN 133
R R +S S +G SS + SRS S S S S S SR R +
Sbjct: 97 KGRERLNS-SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS 155
Query: 134 RRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRN 171
R RSR + K R +ERKRR S ++ TR+
Sbjct: 156 RSRSRERKKSRSR-SRERKRRIRSRSRSRSRHRHRTRS 192
Score = 53.9 bits (128), Expect = 2e-07
Identities = 51/166 (30%), Positives = 70/166 (42%), Gaps = 29/166 (17%)
Query: 25 APSPTKRKDRSDEK-SKDRSKDKG---------ATKESSEKDRGRDKTRKRRSASSGSSS 74
A S T+R + EK S DR K K A+K + R R + RKR+S + G
Sbjct: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
Query: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSG------------ 122
RSRS S + SS S + + SS R +SS +G
Sbjct: 62 -RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
Query: 123 -----SPSPSR-RRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTK 162
S S SR RRH +R R R KS+ R+ K+ + RS K ++
Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR 166
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 10/143 (6%)
Query: 15 KENNKKSSTRAPSPTKR---KDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSG 71
K + +S +R+ S +R + R +KS+ RS+++ +K R R + RK+ + S
Sbjct: 118 KSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER-------KKSRSRSRERKKSRSRSR 170
Query: 72 SSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRH 131
R RS S S S T S S + S S + R S S S + SP P R R+
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
Query: 132 DNRRRSRSKSKPPKRDEKERKRR 154
+ ++ +R +K +++R
Sbjct: 231 TAMDAQEALARRLERAKKLQEQR 253
Score = 45.1 bits (105), Expect = 8e-05
Identities = 57/211 (27%), Positives = 80/211 (37%), Gaps = 22/211 (10%)
Query: 99 SSSASSRSG----SSSTSRSSSSSSSSGSPSP-SRRRHDNRRRSRSKSKPPKRDEKERKR 153
++S + R G +S R S S SP + + H +R RSRS+ + K D + RK
Sbjct: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
Query: 154 RSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENP 213
RS S GR R+ +KD K E S +
Sbjct: 62 RSRSRSKE----GR--RHESKD----------KSSKKHKSEEHNDKEHSSDKGRERLNSS 105
Query: 214 DEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPR-RMLPPPPMWRRSPPRMRR 272
+ E K + G+ + + R R R R RS R +
Sbjct: 106 ENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKS 165
Query: 273 RSRSPRRRSPVRRRSRSPGRRRHRSRSSSNS 303
RSRS R+ +R RSRS R RHR+RS S +
Sbjct: 166 RSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 196
Score = 34.7 bits (78), Expect = 0.11
Identities = 19/41 (46%), Positives = 23/41 (56%)
Query: 265 RSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR 305
RS R R R R R RS R++SRS R R +SRS S +
Sbjct: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 163
Score = 28.9 bits (63), Expect = 5.9
Identities = 19/59 (32%), Positives = 23/59 (38%)
Query: 247 PRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR 305
P + SP R SP + R RS R+R R+HRSRS S R
Sbjct: 13 PEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.119 0.330
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,844,294
Number of Sequences: 37866
Number of extensions: 856470
Number of successful extensions: 43621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1416
Number of HSP's successfully gapped in prelim test: 1181
Number of HSP's that attempted gapping in prelim test: 11828
Number of HSP's gapped (non-prelim): 17583
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.