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Search of human proteins with 6857824
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6857824 RAB, member of RAS oncogene family-like 4 [Homo
sapiens]
(185 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6857824 RAB, member of RAS oncogene family-like 4 [Homo sapiens] 373 e-104
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens] 96 1e-20
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens] 94 9e-20
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap... 93 1e-19
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens] 92 2e-19
gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens] 91 4e-19
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens] 91 7e-19
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa... 90 1e-18
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens] 90 1e-18
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens] 90 1e-18
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens] 89 3e-18
gi|21361884 RAB2B protein isoform 1 [Homo sapiens] 88 4e-18
gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens] 88 5e-18
gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens] 88 5e-18
gi|16933567 mel transforming oncogene [Homo sapiens] 87 6e-18
gi|50234889 RAB43 protein [Homo sapiens] 87 6e-18
gi|4758996 Ras-related protein Rab-33A [Homo sapiens] 87 6e-18
gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo sa... 86 2e-17
gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo sa... 84 5e-17
gi|96975097 RAB6B, member RAS oncogene family [Homo sapiens] 84 5e-17
gi|46361978 RAB26, member RAS oncogene family [Homo sapiens] 84 9e-17
gi|33589861 RAB31, member RAS oncogene family [Homo sapiens] 83 2e-16
gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo sa... 83 2e-16
gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo sa... 83 2e-16
gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo sa... 82 3e-16
gi|34485714 Ras-related protein Rab-23 [Homo sapiens] 82 3e-16
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa... 82 3e-16
gi|34485716 Ras-related protein Rab-23 [Homo sapiens] 82 3e-16
gi|25188193 RAB39B, member RAS oncogene family [Homo sapiens] 81 4e-16
gi|4758984 Ras-related protein Rab-11A [Homo sapiens] 81 4e-16
>gi|6857824 RAB, member of RAS oncogene family-like 4 [Homo sapiens]
Length = 185
Score = 373 bits (958), Expect = e-104
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MVKLAAKCILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELF 60
MVKLAAKCILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELF
Sbjct: 1 MVKLAAKCILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELF 60
Query: 61 IFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLV 120
IFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLV
Sbjct: 61 IFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLV 120
Query: 121 GNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVEV 180
GNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVEV
Sbjct: 121 GNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVEV 180
Query: 181 FRALA 185
FRALA
Sbjct: 181 FRALA 185
>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 96.3 bits (238), Expect = 1e-20
Identities = 56/160 (35%), Positives = 89/160 (55%), Gaps = 6/160 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
I+ D VGK++L F + F SY T G+D ++TV + G+ V+L I+D+AG+E
Sbjct: 13 IIGDSGVGKSSLLLRFADNT--FSGSYITTIGVDFKIRTVEI--NGEKVKLQIWDTAGQE 68
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + + +VYDVT+ ESF N +WL + + +LVGNK D
Sbjct: 69 RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVC--RILVGNKNDDPE 126
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAK 168
R+ V++ +A +A G++ FETS KE N E F+C+ +
Sbjct: 127 RKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITE 166
>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 93.6 bits (231), Expect = 9e-20
Identities = 60/159 (37%), Positives = 83/159 (52%), Gaps = 5/159 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ + VGKT L + F F T G+D ++KTV + G+ V+L I+D+AG+E
Sbjct: 14 LIGNAGVGKTCLVRRFTQ--GLFPPGQGATIGVDFMIKTVEI--NGEKVKLQIWDTAGQE 69
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + S N L L YD+T EESF +WL + A + VLVGNK DLA
Sbjct: 70 RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASN-KVITVLVGNKIDLAE 128
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLA 167
RR V A ++ Q + ETS KE +N E F LA
Sbjct: 129 RREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167
>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
sapiens]
Length = 205
Score = 92.8 bits (229), Expect = 1e-19
Identities = 54/161 (33%), Positives = 90/161 (55%), Gaps = 5/161 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGK+ L F D + +SY T G+D ++T+ + G +++L I+D+AG+E
Sbjct: 16 LIGDSGVGKSCLLLRFADDT--YTESYISTIGVDFKIRTIELD--GKTIKLQIWDTAGQE 71
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + + +VYDVT++ESFNN +WL++ A ++ +LVGNK DL
Sbjct: 72 RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYA-SENVNKLLVGNKCDLTT 130
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQ 169
++ VD A+ +A G+ ETS K N E F +A +
Sbjct: 131 KKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAE 171
>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 92.4 bits (228), Expect = 2e-19
Identities = 52/160 (32%), Positives = 84/160 (52%), Gaps = 5/160 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT L F D +F +Y T G+D ++TV + G ++L ++D+AG+E
Sbjct: 13 LIGDSGVGKTCLIIRFAED--NFNNTYISTIGIDFKIRTVDIE--GKKIKLQVWDTAGQE 68
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + LVYD+T+E+SF N W++ + A + +L+GNK D+
Sbjct: 69 RFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENA-SAGVERLLLGNKCDMEA 127
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAK 168
+R V +A A G+ FETS K N + F LA+
Sbjct: 128 KRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 167
>gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]
Length = 212
Score = 91.3 bits (225), Expect = 4e-19
Identities = 58/170 (34%), Positives = 88/170 (51%), Gaps = 5/170 (2%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
I+ D VGK+ L F FQ + LT G++ + + + G ++L I+D+AG+E
Sbjct: 11 IIGDTGVGKSCLLLQFTDK--RFQPVHDLTIGVEFGARMITID--GKQIKLQIWDTAGQE 66
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + LVYD+T ++FN+ + WLE AR Q ++ +L+GNK+DL
Sbjct: 67 SFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDAR-QHSNSNMVIMLIGNKSDLES 125
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKV 178
RR V E A+A GL ETS K N E F AK+ ++ +E V
Sbjct: 126 RREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGV 175
>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 90.5 bits (223), Expect = 7e-19
Identities = 52/161 (32%), Positives = 91/161 (56%), Gaps = 5/161 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGK+ L F D + +SY T G+D ++T+ + G +++L I+D+AG+E
Sbjct: 13 LIGDSGVGKSCLLLRFADDT--YTESYISTIGVDFKIRTIELD--GKTIKLQIWDTAGQE 68
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + + +VYDVT++ES+ N +WL++ A ++ +LVGNK+DL
Sbjct: 69 RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYA-SENVNKLLVGNKSDLTT 127
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQ 169
++ VD+ A+ +A G+ ETS K N E F +A +
Sbjct: 128 KKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAE 168
>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
family [Homo sapiens]
Length = 327
Score = 89.7 bits (221), Expect = 1e-18
Identities = 51/160 (31%), Positives = 82/160 (51%), Gaps = 5/160 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT L F D +F +Y T G+D ++TV + G ++L ++D+AG+E
Sbjct: 137 LIGDSGVGKTCLIIRFAED--NFNNTYISTIGIDFKIRTVDIE--GKKIKLQVWDTAGQE 192
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + L YD+T+E+SF N W++ A + +L+GNK D+
Sbjct: 193 RFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENA-SAGVEHLLLGNKCDMEA 251
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAK 168
+R V +A A G+ FETS K N + F LA+
Sbjct: 252 KRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 291
>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 89.7 bits (221), Expect = 1e-18
Identities = 51/160 (31%), Positives = 82/160 (51%), Gaps = 5/160 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT L F D +F +Y T G+D ++TV + G ++L ++D+AG+E
Sbjct: 137 LIGDSGVGKTCLIIRFAED--NFNNTYISTIGIDFKIRTVDIE--GKKIKLQVWDTAGQE 192
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + L YD+T+E+SF N W++ A + +L+GNK D+
Sbjct: 193 RFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENA-SAGVEHLLLGNKCDMEA 251
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAK 168
+R V +A A G+ FETS K N + F LA+
Sbjct: 252 KRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 291
>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 89.7 bits (221), Expect = 1e-18
Identities = 51/160 (31%), Positives = 82/160 (51%), Gaps = 5/160 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT L F D +F +Y T G+D ++TV + G ++L ++D+AG+E
Sbjct: 137 LIGDSGVGKTCLIIRFAED--NFNNTYISTIGIDFKIRTVDIE--GKKIKLQVWDTAGQE 192
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + L YD+T+E+SF N W++ A + +L+GNK D+
Sbjct: 193 RFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENA-SAGVEHLLLGNKCDMEA 251
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAK 168
+R V +A A G+ FETS K N + F LA+
Sbjct: 252 KRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 291
>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
Length = 207
Score = 88.6 bits (218), Expect = 3e-18
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 5/160 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT L +FR F ++ T G+D ++T+ + G ++L I+D+AG+E
Sbjct: 13 LIGDSGVGKTCL--LFRFSEDAFNTTFISTIGIDFKIRTIELD--GKKIKLQIWDTAGQE 68
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + LVYD+TNE+SF+N W+ A + +++GNK D+
Sbjct: 69 RFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASS-DVERMILGNKCDMND 127
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAK 168
+R V A+ G++ ETS K N E F LA+
Sbjct: 128 KRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLAR 167
>gi|21361884 RAB2B protein isoform 1 [Homo sapiens]
Length = 216
Score = 88.2 bits (217), Expect = 4e-18
Identities = 58/164 (35%), Positives = 85/164 (51%), Gaps = 5/164 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
I+ D VGK+ L F FQ + LT G++ + V + G ++L I+D+AG+E
Sbjct: 11 IIGDTGVGKSCLLLQFTDK--RFQPVHDLTIGVEFGARMVNID--GKQIKLQIWDTAGQE 66
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + LVYD+T E+FN+ + WLE AR Q ++ +L+GNK+DL
Sbjct: 67 SFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDAR-QHSSSNMVIMLIGNKSDLES 125
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQ 172
RR V E A+A GL ETS K N E F AK+ ++
Sbjct: 126 RRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYR 169
>gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens]
Length = 215
Score = 87.8 bits (216), Expect = 5e-18
Identities = 60/163 (36%), Positives = 89/163 (54%), Gaps = 9/163 (5%)
Query: 9 ILADPAVGKTALAQIFRSDGAH-FQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGK 67
+L + AVGK++L F H FQ+S T G + +TV + DT +V+ I+D+AG+
Sbjct: 25 LLGESAVGKSSLVLRFVKGQFHEFQES---TIGAAFLTQTVCLDDT--TVKFEIWDTAGQ 79
Query: 68 ELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQA-PGISLPGVLVGNKTDL 126
E + + + +VYD+TNEESF W+++ + QA P I + L GNK DL
Sbjct: 80 ERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVI--ALSGNKADL 137
Query: 127 AGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQ 169
A +RAVD EA+++A L ETS K N F +AK+
Sbjct: 138 ANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKK 180
>gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]
Length = 200
Score = 87.8 bits (216), Expect = 5e-18
Identities = 55/160 (34%), Positives = 82/160 (51%), Gaps = 5/160 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT + +FR F ++ T G+D +KTV + G ++L I+D+AG+E
Sbjct: 14 LIGDSGVGKTCV--LFRFSDDAFNTTFISTIGIDFKIKTVELQ--GKKIKLQIWDTAGQE 69
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + LVYD+TN +SF N SKWL A + +L+GNK D+
Sbjct: 70 RFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHA-NEDVERMLLGNKCDMDD 128
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAK 168
+R V + A G+ FETS K N E F LA+
Sbjct: 129 KRVVPKGKGGQIAREHGIRFFETSAKANINIEKAFLTLAE 168
>gi|16933567 mel transforming oncogene [Homo sapiens]
Length = 207
Score = 87.4 bits (215), Expect = 6e-18
Identities = 52/171 (30%), Positives = 86/171 (50%), Gaps = 5/171 (2%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT + +FR F ++ T G+D ++T+ + G ++L I+D+AG+E
Sbjct: 13 LIGDSGVGKTCV--LFRFSEDAFNSTFISTIGIDFKIRTIELD--GKRIKLQIWDTAGQE 68
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + LVYD+TNE+SF+N W+ A + +++GNK D+
Sbjct: 69 RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHA-SADVEKMILGNKCDVND 127
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVE 179
+R V AL G++ ETS K N E F LA+ +K+E
Sbjct: 128 KRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLE 178
>gi|50234889 RAB43 protein [Homo sapiens]
Length = 212
Score = 87.4 bits (215), Expect = 6e-18
Identities = 55/156 (35%), Positives = 85/156 (54%), Gaps = 6/156 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D +VGKT + Q F++ F + T G+D +KT+ + G V+L I+D+AG+E
Sbjct: 23 LVGDASVGKTCVVQRFKTGA--FSERQGSTIGVDFTMKTLEIQ--GKRVKLQIWDTAGQE 78
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + S N L YD+T SF + W+E R A G ++ +L+GNK+DL+
Sbjct: 79 RFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYA-GSNIVQLLIGNKSDLSE 137
Query: 129 RRAVDSAEARAWALGQGLEC-FETSVKEMENFEAPF 163
R V AEA++ A + C ETS K+ N E F
Sbjct: 138 LREVSLAEAQSLAEHYDILCAIETSAKDSSNVEEAF 173
>gi|4758996 Ras-related protein Rab-33A [Homo sapiens]
Length = 237
Score = 87.4 bits (215), Expect = 6e-18
Identities = 62/176 (35%), Positives = 91/176 (51%), Gaps = 12/176 (6%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT L FR G F T G+D KTV + G+ +++ ++D+AG+E
Sbjct: 41 VIGDSNVGKTCLT--FRFCGGTFPDKTEATIGVDFREKTVEIE--GEKIKVQVWDTAGQE 96
Query: 69 LFSE-MLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLA 127
F + M++ + + + + VYDVT SF N W+++ A +P VLVGNK DL
Sbjct: 97 RFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLR 156
Query: 128 GRRAVDSAEARAWALGQGLECFETSV---KEMENFEAPFHCLA----KQFHQLYRE 176
+ V S A +A + FETS KE +N E+ F CLA Q LYR+
Sbjct: 157 EQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRD 212
>gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo
sapiens]
Length = 223
Score = 85.5 bits (210), Expect = 2e-17
Identities = 55/161 (34%), Positives = 81/161 (50%), Gaps = 4/161 (2%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
+L D VGKT F+ DGA ++ T G+D K V V G V+L I+D+AG+E
Sbjct: 34 LLGDTGVGKTCFLIQFK-DGAFLSGTFIATVGIDFRNKVVTVD--GVRVKLQIWDTAGQE 90
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + L L+YD+TN+ SF+N WL + A + +L+GNK D++
Sbjct: 91 RFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQR-DVVIMLLGNKADMSS 149
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQ 169
R + S + A G+ ETS K N E F +AK+
Sbjct: 150 ERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKE 190
>gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo
sapiens]
Length = 208
Score = 84.3 bits (207), Expect = 5e-17
Identities = 55/158 (34%), Positives = 83/158 (52%), Gaps = 5/158 (3%)
Query: 10 LADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKEL 69
L + +VGKT+L F D F +Y T G+D + KT+ + D +V L ++D+AG+E
Sbjct: 19 LGEQSVGKTSLITRFMYDS--FDNTYQATIGIDFLSKTMYLEDR--TVRLQLWDTAGQER 74
Query: 70 FSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGR 129
F ++ V +VYD+TN SF +KW++ R++ G + +LVGNKTDLA +
Sbjct: 75 FRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTER-GSDVIIMLVGNKTDLADK 133
Query: 130 RAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLA 167
R V E A + ETS K N + F +A
Sbjct: 134 RQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVA 171
>gi|96975097 RAB6B, member RAS oncogene family [Homo sapiens]
Length = 208
Score = 84.3 bits (207), Expect = 5e-17
Identities = 55/158 (34%), Positives = 83/158 (52%), Gaps = 5/158 (3%)
Query: 10 LADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKEL 69
L + +VGKT+L F D F +Y T G+D + KT+ + D +V L ++D+AG+E
Sbjct: 19 LGEQSVGKTSLITRFMYDS--FDNTYQATIGIDFLSKTMYLEDR--TVRLQLWDTAGQER 74
Query: 70 FSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGR 129
F ++ V +VYD+TN SF SKW++ R++ G + +LVGNKTDLA +
Sbjct: 75 FRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTER-GSDVIIMLVGNKTDLADK 133
Query: 130 RAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLA 167
R + E A + ETS K N + F +A
Sbjct: 134 RQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVA 171
>gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]
Length = 256
Score = 83.6 bits (205), Expect = 9e-17
Identities = 56/164 (34%), Positives = 82/164 (50%), Gaps = 4/164 (2%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT L F+ DGA ++ T G+D K + V G V+L ++D+AG+E
Sbjct: 68 LVGDSGVGKTCLLVRFK-DGAFLAGTFISTVGIDFRNKVLDVD--GVKVKLQMWDTAGQE 124
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + L L+YDVTN+ SF+N WL + A + +L+GNK D A
Sbjct: 125 RFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQH-DVALMLLGNKVDSAH 183
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQ 172
R V + A GL ETS K N + F +AK+ Q
Sbjct: 184 ERVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQ 227
>gi|33589861 RAB31, member RAS oncogene family [Homo sapiens]
Length = 195
Score = 82.8 bits (203), Expect = 2e-16
Identities = 52/167 (31%), Positives = 84/167 (50%), Gaps = 7/167 (4%)
Query: 8 CILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELF-IFDSAG 66
C+L D VGK+++ F D HF + + T G + KTVP G+ + F I+D+AG
Sbjct: 10 CLLGDTGVGKSSIVCRFVQD--HFDHNISPTIGASFMTKTVPC---GNELHKFLIWDTAG 64
Query: 67 KELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDL 126
+E F + + +VYD+T ++SF KW+++ + P ++ + GNK DL
Sbjct: 65 QERFHSLAPMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPE-NIVMAIAGNKCDL 123
Query: 127 AGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQL 173
+ R V +A+ +A G ETS K N E F +++Q L
Sbjct: 124 SDIREVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQIPPL 170
>gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo
sapiens]
Length = 216
Score = 82.8 bits (203), Expect = 2e-16
Identities = 54/162 (33%), Positives = 86/162 (53%), Gaps = 7/162 (4%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
+L + AVGK++L + R F + T G + +TV + DT +V+ I+D+AG+E
Sbjct: 26 LLGESAVGKSSL--VLRFVKGQFHEYQESTIGAAFLTQTVCLDDT--TVKFEIWDTAGQE 81
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQA-PGISLPGVLVGNKTDLA 127
+ + + +VYD+TN ++F W+++ + QA P I + L GNK DLA
Sbjct: 82 RYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVI--ALAGNKADLA 139
Query: 128 GRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQ 169
+RAV+ EA+A+A L ETS K N F +AK+
Sbjct: 140 SKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKK 181
>gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo
sapiens]
Length = 216
Score = 82.8 bits (203), Expect = 2e-16
Identities = 54/162 (33%), Positives = 86/162 (53%), Gaps = 7/162 (4%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
+L + AVGK++L + R F + T G + +TV + DT +V+ I+D+AG+E
Sbjct: 26 LLGESAVGKSSL--VLRFVKGQFHEYQESTIGAAFLTQTVCLDDT--TVKFEIWDTAGQE 81
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQA-PGISLPGVLVGNKTDLA 127
+ + + +VYD+TN ++F W+++ + QA P I + L GNK DLA
Sbjct: 82 RYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVI--ALAGNKADLA 139
Query: 128 GRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQ 169
+RAV+ EA+A+A L ETS K N F +AK+
Sbjct: 140 SKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKK 181
>gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo
sapiens]
Length = 208
Score = 81.6 bits (200), Expect = 3e-16
Identities = 53/158 (33%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
Query: 10 LADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKEL 69
L + +VGKT+L F D F +Y T G+D + KT+ + D ++ L ++D+AG+E
Sbjct: 19 LGEQSVGKTSLITRFMYDS--FDNTYQATIGIDFLSKTMYLEDR--TIRLQLWDTAGQER 74
Query: 70 FSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGR 129
F ++ +VYD+TN SF +KW++ R++ G + +LVGNKTDLA +
Sbjct: 75 FRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTER-GSDVIIMLVGNKTDLADK 133
Query: 130 RAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLA 167
R V E A + ETS K N + F +A
Sbjct: 134 RQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVA 171
>gi|34485714 Ras-related protein Rab-23 [Homo sapiens]
Length = 237
Score = 81.6 bits (200), Expect = 3e-16
Identities = 55/170 (32%), Positives = 86/170 (50%), Gaps = 6/170 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ + AVGK+++ Q R F K Y T G+D + + + V D + V L ++D+AG+E
Sbjct: 14 VVGNGAVGKSSMIQ--RYCKGIFTKDYKKTIGVDFLERQIQVND--EDVRLMLWDTAGQE 69
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + LV+ T+ ESF S W EK ++ I P VLV NK DL
Sbjct: 70 EFDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVGDI--PTVLVQNKIDLLD 127
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKV 178
+ + EA A A L + TSVKE N F LA+++ Q ++++
Sbjct: 128 DSCIKNEEAEALAKRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQKLKQQI 177
>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
sapiens]
Length = 216
Score = 81.6 bits (200), Expect = 3e-16
Identities = 53/161 (32%), Positives = 80/161 (49%), Gaps = 4/161 (2%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGKT+L F G S++ T G+ K V V G V+L I+D+AG+E
Sbjct: 27 LVGDSGVGKTSLLVQF-DQGKFIPGSFSATVGIGFTNKVVTVD--GVRVKLQIWDTAGQE 83
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + L L+YD+TN+ SF+N WL + A + +L+GNK D++
Sbjct: 84 RFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQR-DVVIMLLGNKADMSS 142
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQ 169
R + S + A G+ ETS K N E F +AK+
Sbjct: 143 ERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKE 183
>gi|34485716 Ras-related protein Rab-23 [Homo sapiens]
Length = 237
Score = 81.6 bits (200), Expect = 3e-16
Identities = 55/170 (32%), Positives = 86/170 (50%), Gaps = 6/170 (3%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ + AVGK+++ Q R F K Y T G+D + + + V D + V L ++D+AG+E
Sbjct: 14 VVGNGAVGKSSMIQ--RYCKGIFTKDYKKTIGVDFLERQIQVND--EDVRLMLWDTAGQE 69
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + LV+ T+ ESF S W EK ++ I P VLV NK DL
Sbjct: 70 EFDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVGDI--PTVLVQNKIDLLD 127
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKV 178
+ + EA A A L + TSVKE N F LA+++ Q ++++
Sbjct: 128 DSCIKNEEAEALAKRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQKLKQQI 177
>gi|25188193 RAB39B, member RAS oncogene family [Homo sapiens]
Length = 213
Score = 81.3 bits (199), Expect = 4e-16
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 3/167 (1%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGK+ L + F F + T G+D + V + + G ++L I+D+AG+E
Sbjct: 13 VIGDSTVGKSCLIRRFTE--GRFAQVSDPTVGVDFFSRLVEI-EPGKRIKLQIWDTAGQE 69
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
F + + + L++D+TN SF N +WLE+ + + VLVG+K DL
Sbjct: 70 RFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDT 129
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYR 175
+R V EA A G++ ETS ++ N E F L + ++L +
Sbjct: 130 QRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVK 176
>gi|4758984 Ras-related protein Rab-11A [Homo sapiens]
Length = 216
Score = 81.3 bits (199), Expect = 4e-16
Identities = 49/169 (28%), Positives = 89/169 (52%), Gaps = 5/169 (2%)
Query: 9 ILADPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKE 68
++ D VGK+ L F + + + T+ G++ +++ V G +++ I+D+AG+E
Sbjct: 16 LIGDSGVGKSNLLSRFTRNEFNLESKSTI--GVEFATRSIQVD--GKTIKAQIWDTAGQE 71
Query: 69 LFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAG 128
+ + + LVYD+ ++ N +WL++ R A ++ +LVGNK+DL
Sbjct: 72 RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADS-NIVIMLVGNKSDLRH 130
Query: 129 RRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREK 177
RAV + EARA+A GL ETS + N EA F + + +++ +K
Sbjct: 131 LRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQK 179
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,976,624
Number of Sequences: 37866
Number of extensions: 289787
Number of successful extensions: 949
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 657
Number of HSP's gapped (non-prelim): 192
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.