Guide to the Human Genome
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Name: CYP2D6 Sequence: fasta or formatted (446aa) NCBI GI: 68509921
Description:

cytochrome P450, family 2, subfamily D, polypeptide 6 isoform 2

Referenced in:

Cytochrome P450 Enzymes

Other entries for this name:
alt prot [497aa] cytochrome P450, family 2, subfamily D, polypeptide 6 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.6         34           2
 C cysteine            1.1          5           1
 D aspartate           5.2         23           2
 E glutamate           5.8         26           2
 F phenylalanine       6.7         30           2
 G glycine             6.5         29           1
 H histidine           3.4         15           2
 I isoleucine          3.4         15           1
 K lysine              2.2         10           1
 L leucine            13.5         60           3
 M methionine          2.2         10           1
 N asparagine          2.2         10           1
 P proline             8.3         37           2
 Q glutamine           4.5         20           2
 R arginine            7.4         33           3
 S serine              4.0         18           2
 T threonine           5.4         24           2
 V valine              8.3         37           3
 W tryptophan          1.1          5           1
 Y tyrosine            1.1          5           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytochrome P450, family 2, subfamily D, polypeptide ... 
CYP2D6                0.973   cytochrome P450, family 2, subfamily D, polypeptide ...
CYP2J2                0.331   cytochrome P450, family 2, subfamily J, polypeptide ...
CYP2C8                0.315   cytochrome P450, family 2, subfamily C, polypeptide ...
CYP2E1                0.305   cytochrome P450, family 2, subfamily E, polypeptide ...
CYP2C19               0.303   cytochrome P450, family 2, subfamily C, polypeptide 1...
CYP2B6                0.301   cytochrome P450, family 2, subfamily B, polypeptide 6...
CYP2C18               0.299   cytochrome P450 family 2 subfamily C polypeptide 18 ...
CYP2C9                0.299   cytochrome P450, family 2, subfamily C, polypeptide ...
CYP2F1                0.297   cytochrome P450, family 2, subfamily F, polypeptide ...
CYP2R1                0.297   cytochrome P450, family 2, subfamily R, polypeptide ...
CYP2U1                0.294   cytochrome P450, family 2, subfamily U, polypeptide ...
CYP2A13               0.291   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP2W1                0.291   cytochrome P450, family 2, subfamily W, polypeptide ...
CYP2A6                0.273   cytochrome P450, family 2, subfamily A, polypeptide...
CYP2A7                0.271   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP2S1                0.262   cytochrome P450, family 2, subfamily S, polypeptide ...
CYP2A7                0.254   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP2C18               0.246   cytochrome P450 family 2 subfamily C polypeptide 18...
CYP1B1                0.215   cytochrome P450, family 1, subfamily B, polypeptide...
CYP1A1                0.209   cytochrome P450, family 1, subfamily A, polypeptide 1...
CYP1A2                0.181   cytochrome P450, family 1, subfamily A, polypeptide ...
CYP21A2               0.152   cytochrome P450, family 21, subfamily A, polypeptide...
CYP21A2               0.143   cytochrome P450, family 21, subfamily A, polypeptid...
CYP17A1               0.135   cytochrome P450, family 17 
CYP4V2                0.085   cytochrome P450, family 4, subfamily v, polypeptide...
CYP3A4                0.082   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP3A7                0.078   cytochrome P450, family 3, subfamily A, polypeptide 7...
CYP3A5                0.078   cytochrome P450, family 3, subfamily A, polypeptide 5...
CYP27C1               0.077   cytochrome P450, family 27, subfamily C, polypeptid...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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