Guide to the Human Genome
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Name: CYP3A4 Sequence: fasta or formatted (503aa) NCBI GI: 13435386
Description:

cytochrome P450, family 3, subfamily A, polypeptide 4

Referenced in:

Nuclear Receptors
Cytochrome P450 Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.0         20           1
 C cysteine            1.4          7           1
 D aspartate           5.2         26           1
 E glutamate           6.2         31           2
 F phenylalanine       6.4         32           2
 G glycine             5.2         26           2
 H histidine           1.6          8           1
 I isoleucine          6.0         30           2
 K lysine              7.6         38           2
 L leucine            11.7         59           3
 M methionine          3.8         19           1
 N asparagine          3.6         18           2
 P proline             7.0         35           2
 Q glutamine           3.0         15           2
 R arginine            4.4         22           2
 S serine              6.2         31           2
 T threonine           5.4         27           2
 V valine              7.8         39           3
 W tryptophan          0.8          4           1
 Y tyrosine            3.2         16           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytochrome P450, family 3, subfamily A, polypeptide ... 
CYP3A7                0.889   cytochrome P450, family 3, subfamily A, polypeptide 7...
CYP3A5                0.853   cytochrome P450, family 3, subfamily A, polypeptide 5...
CYP3A43               0.777   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP3A43               0.772   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP3A43               0.645   cytochrome P450, family 3, subfamily A, polypeptide ...
TBXAS1                0.299   thromboxane A synthase 1, platelet isoform TXS-I [H...
TBXAS1                0.299   thromboxane A synthase 1, platelet isoform TXS-I [H...
TBXAS1                0.228   thromboxane A synthase 1, platelet isoform TXS-II [...
CYP4V2                0.145   cytochrome P450, family 4, subfamily v, polypeptide...
CYP4Z1                0.143   cytochrome P450 4Z1 
CYP4X1                0.136   cytochrome P450, family 4, subfamily X, polypeptide ...
CYP4F12               0.135   cytochrome P450, family 4, subfamily F, polypeptide...
CYP4F8                0.131   cytochrome P450, family 4, subfamily F, polypeptide 8...
CYP4F22               0.130   cytochrome P450, family 4, subfamily F, polypeptide...
CYP4F11               0.129   cytochrome P450 family 4 subfamily F polypeptide 11...
CYP4F11               0.129   cytochrome P450 family 4 subfamily F polypeptide 11...
CYP4A11               0.127   cytochrome P450, family 4, subfamily A, polypeptide...
CYP4B1                0.126   cytochrome P450, family 4, subfamily B, polypeptide...
CYP4A22               0.125   cytochrome P450, family 4, subfamily A, polypeptide ...
CYP4B1                0.125   cytochrome P450, family 4, subfamily B, polypeptide...
CYP4F3                0.124   cytochrome P450, family 4, subfamily F, polypeptide...
CYP46A1               0.123   cytochrome P450, family 46 
CYP4F2                0.119   cytochrome P450, family 4, subfamily F, polypeptide ...
CYP27B1               0.117   cytochrome P450, family 27, subfamily B, polypeptide ...
CYP2U1                0.112   cytochrome P450, family 2, subfamily U, polypeptide ...
CYP2J2                0.107   cytochrome P450, family 2, subfamily J, polypeptide ...
CYP24A1               0.105   cytochrome P450 family 24 subfamily A polypeptide 1 ...
CYP2C9                0.104   cytochrome P450, family 2, subfamily C, polypeptide ...
CYP2R1                0.103   cytochrome P450, family 2, subfamily R, polypeptide ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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