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Search of human proteins with 68508961
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68508961 centromere protein C 1 [Homo sapiens]
(943 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68508961 centromere protein C 1 [Homo sapiens] 1878 0.0
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 62 3e-09
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 62 3e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 54 7e-07
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 54 9e-07
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 54 9e-07
gi|87299628 biorientation of chromosomes in cell division 1-like... 52 2e-06
gi|47578107 delangin isoform B [Homo sapiens] 51 6e-06
gi|47578105 delangin isoform A [Homo sapiens] 51 6e-06
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 49 2e-05
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 49 2e-05
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 48 4e-05
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 47 1e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 47 1e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 4e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 45 4e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 45 4e-04
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 45 4e-04
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 45 4e-04
gi|60097902 filaggrin [Homo sapiens] 44 5e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 44 7e-04
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 44 7e-04
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens] 44 7e-04
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens] 44 7e-04
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 44 0.001
gi|67551265 transcription factor ELYS [Homo sapiens] 44 0.001
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 43 0.001
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 43 0.002
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 42 0.002
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 42 0.002
>gi|68508961 centromere protein C 1 [Homo sapiens]
Length = 943
Score = 1878 bits (4866), Expect = 0.0
Identities = 943/943 (100%), Positives = 943/943 (100%)
Query: 1 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP 60
MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP
Sbjct: 1 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP 60
Query: 61 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI 120
NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI
Sbjct: 61 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI 120
Query: 121 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK 180
LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK
Sbjct: 121 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK 180
Query: 181 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS 240
RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS
Sbjct: 181 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS 240
Query: 241 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE 300
GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE
Sbjct: 241 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE 300
Query: 301 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN 360
DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN
Sbjct: 301 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN 360
Query: 361 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK 420
DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK
Sbjct: 361 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK 420
Query: 421 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP 480
QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP
Sbjct: 421 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP 480
Query: 481 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV 540
VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV
Sbjct: 481 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV 540
Query: 541 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS 600
YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS
Sbjct: 541 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS 600
Query: 601 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG 660
GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG
Sbjct: 601 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG 660
Query: 661 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP 720
YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP
Sbjct: 661 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP 720
Query: 721 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK 780
KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK
Sbjct: 721 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK 780
Query: 781 RKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDL 840
RKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDL
Sbjct: 781 RKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDL 840
Query: 841 VRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLL 900
VRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLL
Sbjct: 841 VRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLL 900
Query: 901 CTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR 943
CTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR
Sbjct: 901 CTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR 943
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 62.0 bits (149), Expect = 3e-09
Identities = 72/363 (19%), Positives = 146/363 (40%), Gaps = 18/363 (4%)
Query: 282 HAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALL 341
+A PP P K +E+ QSF S + I ++G +R + S
Sbjct: 258 NAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAA---IEPESGKSNERKGGRSRSHTRS 314
Query: 342 QGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYE 401
+ R S + H + + KH + H S+ D+ + + ++ R ++
Sbjct: 315 KSRSSSKSHSR---RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKSRSR 370
Query: 402 MYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRN 461
+S++ K +R K IK+K+R K + E + + + K++ + E +++ +++
Sbjct: 371 SHSRDKRKDTREK--IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKD 428
Query: 462 MEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSR 521
E+ E + +K K+ +DKE+ ++K S E K ++ + T +S
Sbjct: 429 KEKDREREREKEHEKDR----DKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484
Query: 522 RISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRK-STKKTNQSSKNIRKKTIPLKR 580
SRR + S+ S R + SSR S + N+ K K+ +
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 544
Query: 581 QKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSS 640
++ + + + +G + E + SL E + E D + K +D + R+
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKL----EKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Query: 641 KNE 643
+N+
Sbjct: 601 ENK 603
Score = 32.0 bits (71), Expect = 2.8
Identities = 74/403 (18%), Positives = 141/403 (34%), Gaps = 65/403 (16%)
Query: 42 FEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVV 101
F ++ L + S N+ P T Q+ +KE ++ V ++ ++ + +
Sbjct: 246 FGDRPLKINHSNNAIVKPPEMTP-------QAAAKELEE-----VMKRVREAQSFISAAI 293
Query: 102 EPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSV 161
EP + + + SS + +K R+ + H S + S S
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK---RSQSKHRSRSHNR------SRSR 344
Query: 162 LLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEID 221
D + S S + S +++R + T +K K+R+ D+ ++ E +
Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 404
Query: 222 NKVSDEE------DKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSE 275
+ E DK E K + R R+ E+E R +K E K K
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE-----KEQDKEKER 459
Query: 276 SSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPA 335
D +K I+++ D+ ++ RS+ R S ++R
Sbjct: 460 EK----------------DRSKEIDEKRKKDKKSRT-PPRSYNASRRSRSSSRER----- 497
Query: 336 ESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNY 395
+ R+SR + K S P P ++ K + + I E
Sbjct: 498 ------RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH--ISERRERE 549
Query: 396 RSTKYEMYSKN---AEKPSRSKRTIKQKQRRKFMAKPAEEQLD 435
RST S + EK ++ ++K+K+ K +++D
Sbjct: 550 RSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 592
Score = 31.2 bits (69), Expect = 4.8
Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 31/160 (19%)
Query: 219 EIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSP 278
EID K ++DK S R + S ++R E +R S S +T+KRKS SP
Sbjct: 466 EIDEK--RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 523
Query: 279 IVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAEST 338
P S D K ++ I E + ++R+ S +S+
Sbjct: 524 --------SPRSRNKKDKKREKERDHISERRE-----------------RERSTSMRKSS 558
Query: 339 ALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDK 378
G++ EK+ +L +H+ +P + + DK
Sbjct: 559 NDRDGKEKLEKNST----SLKEKEHNKEPDSSVSKEVDDK 594
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 62.0 bits (149), Expect = 3e-09
Identities = 72/363 (19%), Positives = 146/363 (40%), Gaps = 18/363 (4%)
Query: 282 HAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALL 341
+A PP P K +E+ QSF S + I ++G +R + S
Sbjct: 142 NAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAA---IEPESGKSNERKGGRSRSHTRS 198
Query: 342 QGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYE 401
+ R S + H + + KH + H S+ D+ + + ++ R ++
Sbjct: 199 KSRSSSKSHSR---RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKSRSR 254
Query: 402 MYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRN 461
+S++ K +R K IK+K+R K + E + + + K++ + E +++ +++
Sbjct: 255 SHSRDKRKDTREK--IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKD 312
Query: 462 MEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSR 521
E+ E + +K K+ +DKE+ ++K S E K ++ + T +S
Sbjct: 313 KEKDREREREKEHEKDR----DKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368
Query: 522 RISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRK-STKKTNQSSKNIRKKTIPLKR 580
SRR + S+ S R + SSR S + N+ K K+ +
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 428
Query: 581 QKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSS 640
++ + + + +G + E + SL E + E D + K +D + R+
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKL----EKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Query: 641 KNE 643
+N+
Sbjct: 485 ENK 487
Score = 32.0 bits (71), Expect = 2.8
Identities = 74/403 (18%), Positives = 141/403 (34%), Gaps = 65/403 (16%)
Query: 42 FEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVV 101
F ++ L + S N+ P T Q+ +KE ++ V ++ ++ + +
Sbjct: 130 FGDRPLKINHSNNAIVKPPEMTP-------QAAAKELEE-----VMKRVREAQSFISAAI 177
Query: 102 EPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSV 161
EP + + + SS + +K R+ + H S + S S
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK---RSQSKHRSRSHNR------SRSR 228
Query: 162 LLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEID 221
D + S S + S +++R + T +K K+R+ D+ ++ E +
Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 288
Query: 222 NKVSDEE------DKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSE 275
+ E DK E K + R R+ E+E R +K E K K
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE-----KEQDKEKER 343
Query: 276 SSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPA 335
D +K I+++ D+ ++ RS+ R S ++R
Sbjct: 344 EK----------------DRSKEIDEKRKKDKKSRT-PPRSYNASRRSRSSSRER----- 381
Query: 336 ESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNY 395
+ R+SR + K S P P ++ K + + I E
Sbjct: 382 ------RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH--ISERRERE 433
Query: 396 RSTKYEMYSKN---AEKPSRSKRTIKQKQRRKFMAKPAEEQLD 435
RST S + EK ++ ++K+K+ K +++D
Sbjct: 434 RSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 476
Score = 31.2 bits (69), Expect = 4.8
Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 31/160 (19%)
Query: 219 EIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSP 278
EID K ++DK S R + S ++R E +R S S +T+KRKS SP
Sbjct: 350 EIDEK--RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 407
Query: 279 IVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAEST 338
P S D K ++ I E + ++R+ S +S+
Sbjct: 408 --------SPRSRNKKDKKREKERDHISERRE-----------------RERSTSMRKSS 442
Query: 339 ALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDK 378
G++ EK+ +L +H+ +P + + DK
Sbjct: 443 NDRDGKEKLEKNST----SLKEKEHNKEPDSSVSKEVDDK 478
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 53.9 bits (128), Expect = 7e-07
Identities = 103/506 (20%), Positives = 198/506 (39%), Gaps = 33/506 (6%)
Query: 72 QSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTP 131
+SP KE KS P V K K + + P EA + + + ++ + + +
Sbjct: 531 KSPEKEEAKS-PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 132 DSKK--ISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQKRETYTFENS 189
+ K +++ S EE + S + + S ++ P A K T S
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA-KSPTKEEAKS 648
Query: 190 VNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQER--KPSGSSQNRI 247
S + K+ ++ K K E E K+ E + K S +
Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708
Query: 248 RDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDE 307
+ E + +K+ S + E + SP V+ A +P + P+ K ++ + +
Sbjct: 709 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSP-VKEEAKSPEKAKSPEKAKTLDVKSPEAK 767
Query: 308 SDQSFASRSWIT-IPRKAGS-LKQRTISPAESTA-LLQGRKSREKHHNILPKTLANDKHS 364
+ +RS P KA S +K+ SP ++ + L + K+ EK + + K
Sbjct: 768 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE 827
Query: 365 HKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRK 424
KP V+ +P K + + A +T S K E K A KP ++++
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPAT-PKTEEKKDSKKEEAPKKEAPKPK------VEEKKEP 880
Query: 425 FMAKPAEEQLDVGQSKDENIHTSHITQDE----FQRNSDRNMEEHEEMGNDCVSKKQMPP 480
+ KP E +++ + + E+ + E + D +E E V+KK+
Sbjct: 881 AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTE-----VAKKEPDD 935
Query: 481 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRR----ISRRPSDWWVVKSE 536
+K+ S +K+E+ ++ ++ + PEE T K++ +S+ PS K+E
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 537 ESPVYSNSSVRNELPMHHNSSRKSTK 562
+S S++ ++ P + K+ K
Sbjct: 996 KS---SSTDQKDSKPPEKATEDKAAK 1018
Score = 44.3 bits (103), Expect = 5e-04
Identities = 80/436 (18%), Positives = 162/436 (37%), Gaps = 49/436 (11%)
Query: 184 YTFENSVNMLPS-STEVSVKTKKRLNFDDKVMLKKI-----------------EIDNKVS 225
++ + +PS ST + VK+++++ +K + + E + +
Sbjct: 420 FSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAK 479
Query: 226 DEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAAT 285
+EE K EG E + + + + E +K + E K +E+ + A
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539
Query: 286 APPHSCPPDDTKLIEDEFIIDESD------QSFASRSWITIPRKAGS-LKQRTISPAEST 338
+P P+ K E + + S + + P KA S K+ SPAE+
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA- 598
Query: 339 ALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRST 398
KS EK + + + + + P E P++ + + + E +
Sbjct: 599 ------KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA 652
Query: 399 KYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNS 458
K + A+ P ++K +K + + AK + K ++ E ++
Sbjct: 653 K-SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 459 DRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVT 518
+ + E V ++ P K S K++ +S +K S E K K + + T
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTP--EKAKSPVKEEAKSPEKAKSPE-KAKTLDVKSPEAKT 768
Query: 519 KSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPL 578
++ +R P+D + P + S V+ E+ S + K + +K IP
Sbjct: 769 PAKEEARSPAD-------KFPEKAKSPVKEEV-----KSPEKAKSPLKEDAKAPEKEIPK 816
Query: 579 KRQ-KTATKGNQRVQK 593
K + K+ K ++ Q+
Sbjct: 817 KEEVKSPVKEEEKPQE 832
Score = 30.8 bits (68), Expect = 6.2
Identities = 39/215 (18%), Positives = 74/215 (34%), Gaps = 28/215 (13%)
Query: 57 KSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEV 116
KS K ++ ++ P K+ ++ + P + +KK++ + EA + +V
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDS------KKEEAPKKEAPKPKV 874
Query: 117 HQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNV--- 173
+ K P +K + EA+++ V +P AK V ++
Sbjct: 875 EE---------KKEPAVEKPKESKVEAKKEEAEDK--KKVPTPEKEAPAKVEVKEDAKPK 923
Query: 174 --------IPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVS 225
P A+ +E P + + K+ K K E D +S
Sbjct: 924 EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983
Query: 226 DEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKK 260
E K + K S + Q + E + +A K
Sbjct: 984 KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 53.5 bits (127), Expect = 9e-07
Identities = 141/736 (19%), Positives = 277/736 (37%), Gaps = 148/736 (20%)
Query: 40 DCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQF 99
DC E+ +F + + S + +SP C S +S P+ + + L
Sbjct: 487 DCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLS- 545
Query: 100 VVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSP 159
++ S+Q V + S+ P+S + S + S+ ++F+L G
Sbjct: 546 ----PGSSEMSLQPDLVRYD----NTESEFLPESSSVKSCK-HKEKSKHQKDFHLEFGEK 596
Query: 160 SVLLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLK-KI 218
S +AK + + TFENS L K+++ + K + K K+
Sbjct: 597 S---NAKIK----------DEDHSPTFENSDCTL-----------KKMDKEGKTLKKHKL 632
Query: 219 EIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAK-----------KSFST--L 265
+ + ++ K EG++ K + +DS E+QR + KS T L
Sbjct: 633 KHKEREKEKHKKEIEGEKEK------YKTKDSAKELQRSVEFDREFWKENFFKSDETEDL 686
Query: 266 FLE------TVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWIT 319
FL T+++KS+ ++ + + E + I ES++SF
Sbjct: 687 FLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKD 746
Query: 320 IPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKT 379
+ + ++ T +E T+L +++ K + D + H E+ + +K
Sbjct: 747 LKEERENIP--TDKDSEFTSLGMSAIEESIGLHLVEKEI--DIEKQEKHIKESKEKPEK- 801
Query: 380 VLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQS 439
+ ++ K+ EK R +T +++++ K K +++LD+ +
Sbjct: 802 -------------------RSQIKEKDIEKMER--KTFEKEKKIKHEHKSEKDKLDLSEC 840
Query: 440 KDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRK-DKEESKKK 498
D+ + + ++++ +E E+ N KK S++ RK DKE+ +K+
Sbjct: 841 VDKIKEKDKL----YSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKE 896
Query: 499 RFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSR 558
R +ESK K + E+ K ++ YS S +
Sbjct: 897 RHLAESKEKHLMEKKN-------------------KQSDNSEYSKSEKGKNKEKDRELDK 937
Query: 559 KSTKKTNQSSKNIRKKTIPLKRQKTATKGNQ-RVQKFLNAEGSGGIVGHDEISRCSLSEP 617
K + +S K I +++ + GN+ + +K L+ + + EP
Sbjct: 938 KEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLS------------LKEKTKDEP 985
Query: 618 LESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHK 677
L++ + KK+ D R K++D I + LK S D + K
Sbjct: 986 LKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLK-------------SEADKPKPK 1032
Query: 678 TS-VLEESGP--SRLNNNYLMS-------GKNDVDDEEVHGSSDDSKQSKVIPKNRIHHK 727
+S +++ P RL N+ LM D++ E+ H + + K K R+ ++
Sbjct: 1033 SSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQK--EKERLRNR 1090
Query: 728 LVLPSNTPNVRRTKRT 743
L + +TK T
Sbjct: 1091 NCLELKIKDKEKTKHT 1106
Score = 46.6 bits (109), Expect = 1e-04
Identities = 97/538 (18%), Positives = 195/538 (36%), Gaps = 91/538 (16%)
Query: 115 EVHQKILATDVSSKNTPDSKKISSRNI---------NDHHSEADEEFYLSVGSPSVLLDA 165
E H+K + + T DS K R++ N S+ E+ +L++ S+ L+
Sbjct: 640 EKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEK 699
Query: 166 KTSVSQNVIPSSAQKRETYT----FENSVNMLPSSTEVSVKTKK-------RLNF----- 209
K+ + +N+ + K + + F+ + + +E S + +K R N
Sbjct: 700 KSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKD 759
Query: 210 -----------DDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRD--------- 249
++ + L +E + + +E E +E KP SQ + +D
Sbjct: 760 SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKE-KPEKRSQIKEKDIEKMERKTF 818
Query: 250 -SEYEIQRQAKKSFSTLFL-ETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDE 307
E +I+ + K L L E V + E + H C + K I
Sbjct: 819 EKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT----EKCHKEGEKSKNTAAIKKT 874
Query: 308 SDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGR---------------KSREKHHN 352
D+ + K K+R ++ ++ L++ + K++EK
Sbjct: 875 DDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRE 934
Query: 353 ILPKTLANDKHS-HKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSK--NAEK 409
+ K + DK S + + + +++D + A + ++ TK E EK
Sbjct: 935 LDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEK 994
Query: 410 PSRSKRTIKQKQRRKFMAKPAEEQL-------------DVGQSKDENIHTSHITQDEFQR 456
+ K + K+R K K L SKD + D+ +
Sbjct: 995 DKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQ 1054
Query: 457 NS--------DRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKL 508
S D +E+ + + + +K+ + ++ K K++ K K +ESKNK
Sbjct: 1055 TSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKE 1114
Query: 509 VPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQ 566
+ +S VT + ++P D +S+ + ++ + NS +S + N+
Sbjct: 1115 LTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1172
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 53.5 bits (127), Expect = 9e-07
Identities = 141/736 (19%), Positives = 277/736 (37%), Gaps = 148/736 (20%)
Query: 40 DCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQF 99
DC E+ +F + + S + +SP C S +S P+ + + L
Sbjct: 510 DCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLS- 568
Query: 100 VVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSP 159
++ S+Q V + S+ P+S + S + S+ ++F+L G
Sbjct: 569 ----PGSSEMSLQPDLVRYD----NTESEFLPESSSVKSCK-HKEKSKHQKDFHLEFGEK 619
Query: 160 SVLLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLK-KI 218
S +AK + + TFENS L K+++ + K + K K+
Sbjct: 620 S---NAKIK----------DEDHSPTFENSDCTL-----------KKMDKEGKTLKKHKL 655
Query: 219 EIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAK-----------KSFST--L 265
+ + ++ K EG++ K + +DS E+QR + KS T L
Sbjct: 656 KHKEREKEKHKKEIEGEKEK------YKTKDSAKELQRSVEFDREFWKENFFKSDETEDL 709
Query: 266 FLE------TVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWIT 319
FL T+++KS+ ++ + + E + I ES++SF
Sbjct: 710 FLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKD 769
Query: 320 IPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKT 379
+ + ++ T +E T+L +++ K + D + H E+ + +K
Sbjct: 770 LKEERENIP--TDKDSEFTSLGMSAIEESIGLHLVEKEI--DIEKQEKHIKESKEKPEK- 824
Query: 380 VLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQS 439
+ ++ K+ EK R +T +++++ K K +++LD+ +
Sbjct: 825 -------------------RSQIKEKDIEKMER--KTFEKEKKIKHEHKSEKDKLDLSEC 863
Query: 440 KDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRK-DKEESKKK 498
D+ + + ++++ +E E+ N KK S++ RK DKE+ +K+
Sbjct: 864 VDKIKEKDKL----YSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKE 919
Query: 499 RFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSR 558
R +ESK K + E+ K ++ YS S +
Sbjct: 920 RHLAESKEKHLMEKKN-------------------KQSDNSEYSKSEKGKNKEKDRELDK 960
Query: 559 KSTKKTNQSSKNIRKKTIPLKRQKTATKGNQ-RVQKFLNAEGSGGIVGHDEISRCSLSEP 617
K + +S K I +++ + GN+ + +K L+ + + EP
Sbjct: 961 KEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLS------------LKEKTKDEP 1008
Query: 618 LESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHK 677
L++ + KK+ D R K++D I + LK S D + K
Sbjct: 1009 LKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLK-------------SEADKPKPK 1055
Query: 678 TS-VLEESGP--SRLNNNYLMS-------GKNDVDDEEVHGSSDDSKQSKVIPKNRIHHK 727
+S +++ P RL N+ LM D++ E+ H + + K K R+ ++
Sbjct: 1056 SSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQK--EKERLRNR 1113
Query: 728 LVLPSNTPNVRRTKRT 743
L + +TK T
Sbjct: 1114 NCLELKIKDKEKTKHT 1129
Score = 46.6 bits (109), Expect = 1e-04
Identities = 97/538 (18%), Positives = 195/538 (36%), Gaps = 91/538 (16%)
Query: 115 EVHQKILATDVSSKNTPDSKKISSRNI---------NDHHSEADEEFYLSVGSPSVLLDA 165
E H+K + + T DS K R++ N S+ E+ +L++ S+ L+
Sbjct: 663 EKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEK 722
Query: 166 KTSVSQNVIPSSAQKRETYT----FENSVNMLPSSTEVSVKTKK-------RLNF----- 209
K+ + +N+ + K + + F+ + + +E S + +K R N
Sbjct: 723 KSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKD 782
Query: 210 -----------DDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRD--------- 249
++ + L +E + + +E E +E KP SQ + +D
Sbjct: 783 SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKE-KPEKRSQIKEKDIEKMERKTF 841
Query: 250 -SEYEIQRQAKKSFSTLFL-ETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDE 307
E +I+ + K L L E V + E + H C + K I
Sbjct: 842 EKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT----EKCHKEGEKSKNTAAIKKT 897
Query: 308 SDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGR---------------KSREKHHN 352
D+ + K K+R ++ ++ L++ + K++EK
Sbjct: 898 DDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRE 957
Query: 353 ILPKTLANDKHS-HKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSK--NAEK 409
+ K + DK S + + + +++D + A + ++ TK E EK
Sbjct: 958 LDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEK 1017
Query: 410 PSRSKRTIKQKQRRKFMAKPAEEQL-------------DVGQSKDENIHTSHITQDEFQR 456
+ K + K+R K K L SKD + D+ +
Sbjct: 1018 DKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQ 1077
Query: 457 NS--------DRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKL 508
S D +E+ + + + +K+ + ++ K K++ K K +ESKNK
Sbjct: 1078 TSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKE 1137
Query: 509 VPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQ 566
+ +S VT + ++P D +S+ + ++ + NS +S + N+
Sbjct: 1138 LTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1195
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 52.4 bits (124), Expect = 2e-06
Identities = 167/837 (19%), Positives = 298/837 (35%), Gaps = 172/837 (20%)
Query: 28 TEQGQNVLEILQDCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVP 87
T++ N++ + +D +E S + ST+ + P+S K ++ +K
Sbjct: 294 TKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEK--------GERKKEKKEKTEKK 345
Query: 88 VSSKKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSE 147
KK Q V + +A + V++ ++ S KN+ +K +
Sbjct: 346 FDHSKKSEDTQKVKDEKQAKEKEVESLKL--------PSEKNSNKAKTVEG--------- 388
Query: 148 ADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRL 207
E+F L ++ V+ L T SV T
Sbjct: 389 TKEDFSL-------------------------------IDSDVDGLTDITVSSVHTSDLS 417
Query: 208 NFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFL 267
+F++ ++EE TS+ E + I + E +Q K T
Sbjct: 418 SFEED------------TEEEVVTSDSME-------EGEITSDDEEKNKQNKTKTQTSDS 458
Query: 268 ETVKRKSESSPIVRHAATAPP--HSCPPDDTKLIEDEFIIDESDQSFAS-------RSWI 318
K KS VRHA P +S D+ +DE +++ QS A R I
Sbjct: 459 SEGKTKS-----VRHAYVHKPYLYSKYYSDS---DDELTVEQRRQSIAKEKEERLLRRQI 510
Query: 319 TIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDK 378
+ KQ+ S QGR S + + K+L K E K
Sbjct: 511 NREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEES-STKSLEPKAARIKEVLKERKVLEKK 569
Query: 379 TVLDTSYALIGETV--NNYRSTKYEMYSKNAEKPSR--------SKRTIKQKQRRKFMAK 428
L V N+ + +YE SK K S S + +K + +K
Sbjct: 570 VALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSK 629
Query: 429 PAEEQLDVGQSKDENIHTSHITQDEFQRNS-------------DRNMEEHEEMGNDCVSK 475
PA + DEN + S + ++ +R S R+++ E C +
Sbjct: 630 PARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEE 689
Query: 476 KQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKS 535
Q K+ ST K+++ KK + L+ +EV S+ K R
Sbjct: 690 PQ------KQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPER------------- 730
Query: 536 EESPVYSNSSVRNELP---MHHNSSR---KSTKKTNQSSKNIRKKTIPLK---RQKTATK 586
E++P SV+++ MH S++K + +NI+K++ K KT K
Sbjct: 731 EKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERK 790
Query: 587 GNQRVQKFLNAEGSGG------IVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSS 640
R ++ L+ G G I+ DE R ++ A+ K ++ RS+ S
Sbjct: 791 SKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEH-KSRRSSDSK 849
Query: 641 KNEDNIMTAQN-VPLKPQTSGYT---CNIPTESNLDSGEHKTSVLEES---GPSRLNNNY 693
+D++ + Q+ + L+ ++ Y+ C++ + +N+DS V+ + S L
Sbjct: 850 IQKDSLGSKQHGITLQRRSESYSEDKCDMDS-TNMDSNLKPEEVVHKEKRRTKSLLEEKL 908
Query: 694 LMSGKNDVDDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRG 753
++ K S KQ KV+ + + + TP + K T E R
Sbjct: 909 VLKSK----------SKTQGKQVKVV-ETELQEGATKQATTPKPDKEKNTEENDSEKQRK 957
Query: 754 ERIDYQGRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLDNDERKTNL 810
++ + +P + VL + S+ K++ + K++ D D T L
Sbjct: 958 SKV--EDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRL 1012
Score = 43.1 bits (100), Expect = 0.001
Identities = 136/697 (19%), Positives = 260/697 (37%), Gaps = 108/697 (15%)
Query: 122 ATDVSSKNTPD--SKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQ 179
+T+ S+ T + SKK+ S+ D ++ + + + D + S + S +
Sbjct: 221 STETSNAKTSERASKKLPSQPTTDTSTDKER-------TSEDMADKEKSTAD----SGGE 269
Query: 180 KRETYTFENSVNMLPSSTE-VSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERK 238
ET + LP E + TK+ N ++L K ++ + S++++K+++ E+K
Sbjct: 270 GLETAPKSEEFSDLPCPVEEIKNYTKEHNNL---ILLNK-DVQQESSEQKNKSTDKGEKK 325
Query: 239 PSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAP-PHSCPPDDTK 297
P + + R E + + + K S +T K K E + + P + K
Sbjct: 326 PDSNEKGE-RKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAK 384
Query: 298 LIE---DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNIL 354
+E ++F + +SD L T+S ++ L + E+
Sbjct: 385 TVEGTKEDFSLIDSD--------------VDGLTDITVSSVHTSDLSSFEEDTEEE---- 426
Query: 355 PKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGET--VNNYRSTKYEMYSKNAEKPSR 412
T + + E +KT TS + G+T V + K +YSK S
Sbjct: 427 VVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYY---SD 483
Query: 413 SKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDC 472
S + +QRR+ +AK EE+L Q E + + E ++S + + +
Sbjct: 484 SDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEE 543
Query: 473 VSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWV 532
S K + P ++ K+++ +KK + K K V K ++ +
Sbjct: 544 SSTKSLEPKAARIKEVLKERKVLEKK-VALSKKRKKDSRNVEENSKKKQQYEEDSKE--T 600
Query: 533 VKSEESPVYSNSSVRNELPMHHNSSR--KSTKKTNQS------SKNIRKKTIPLKRQKTA 584
+K+ E S EL H S K ++ ++S +KN K KR+ +
Sbjct: 601 LKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTST 660
Query: 585 TKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNL---DCSRSTRSSK 641
+ VQ+ + V EI +E + ++ L +K+L D S
Sbjct: 661 PVIMEGVQEETDTRDVKRQVERSEI----CTEEPQKQKSTLKNEKHLKKDDSETPHLKSL 716
Query: 642 NEDNIMTAQNVPLKPQTSGYTCNIPTESNLD-SGEHKTSVLEESGPSRLNNNYLMSGKND 700
+ + +++ P + +T P+E L ++K + ++G
Sbjct: 717 LKKEVKSSKEKPEREKT-------PSEDKLSVKHKYKGDCMHKTG--------------- 754
Query: 701 VDDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQG 760
D+ E+H S K + I K K L S+ R++K + L + G
Sbjct: 755 -DETELHSSEKGLKVEENIQKQSQQTK--LSSDDKTERKSKHRNERKLSV-----LGKDG 806
Query: 761 RPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKK 797
+P ++I K EN+ K N K ++
Sbjct: 807 KPVSEYII-------------KTDENVRKENNKKERR 830
Score = 32.3 bits (72), Expect = 2.1
Identities = 63/402 (15%), Positives = 144/402 (35%), Gaps = 72/402 (17%)
Query: 104 SEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLL 163
+E+ N +++I + + +K ++ I+ H EAD +
Sbjct: 2712 NESLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPK------------ 2759
Query: 164 DAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNK 223
+ + +P +K+ + E+ + P + ++T +R + +
Sbjct: 2760 --EVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQC-----------PETE 2806
Query: 224 VSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFL-------ETVKRKSES 276
D +++ S E P SS+ S ++ S T +T+K + E
Sbjct: 2807 PHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEED 2866
Query: 277 SPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAE 336
PI+ P P + T ++D+ S +T+ + S K +
Sbjct: 2867 QPIIIKRKRGRPRKYPVETTLKMKDD--------SKTDTGIVTVEQSPSSSKLK------ 2912
Query: 337 STALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYR 396
++Q +S ++ N+ ++++ND K + TS G R
Sbjct: 2913 ---VMQTDESNKETANLQERSISNDDGEEK--------------IVTSVRRRGRKPK--R 2953
Query: 397 STKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQR 456
S ++++E + ++++ K + EE+ + + + T T+ E QR
Sbjct: 2954 SLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQR 3013
Query: 457 NSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKK 498
+ ++ K+++ P G++ ++ +E KK
Sbjct: 3014 SK-------TQLSPSIKRKREVSPPGARTRGQQRVEEAPVKK 3048
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 50.8 bits (120), Expect = 6e-06
Identities = 141/700 (20%), Positives = 253/700 (36%), Gaps = 105/700 (15%)
Query: 71 IQSPSKECQKSHPKSVPVS--------SKKKEASLQFVVEPSEATNRSVQAHEVHQKILA 122
+QS S C S P+ VP +KK+ ++ + E + +K
Sbjct: 297 LQSQSLPC--SSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQS----------EKAAM 344
Query: 123 TDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQ--- 179
D+ S + DS K++ R S+ D++ + G + ++VS+N IP + Q
Sbjct: 345 YDIISSPSKDSTKLTLRLSRVRSSDMDQQEDMISGVEN------SNVSENDIPFNVQYPG 398
Query: 180 -KRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERK 238
+T +N P + + +++ F + ++ + V+ ++ +TS Q ++
Sbjct: 399 QTSKTPITPQDINR-PLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQ 457
Query: 239 PSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKL 298
S Q I D E++ A L ++R S I R +
Sbjct: 458 QI-SQQGPIYD---EVELDA--------LAEIERIERESAIERERFSKE----------- 494
Query: 299 IEDEFIIDESDQSFASRSWITIPRKAGSL-------KQRTISPAEST--ALLQGRKSREK 349
+ + D+ R + P++AG Q T S + AL+ +
Sbjct: 495 ------VQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQA 548
Query: 350 HHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGE---TVNNYRSTKYEMYSKN 406
++ D S K P E Q +D V ++G T N+ T K
Sbjct: 549 GRVDSQASITQDSDSIKK-PEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP-----KK 602
Query: 407 AEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHE 466
P SK +KQ + R +KP E +L +S + + T TQ E + ++ E +
Sbjct: 603 KSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTECK 662
Query: 467 EMGNDCVSKKQ-------MPPVGSK----KSSTRKDKEESKKKRFSSESKNKLVPEEVTS 515
+ + V KQ P +K +S T K + E+ K++ S + +
Sbjct: 663 QNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHP 722
Query: 516 TVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMH-HNSSRKSTKKTNQSSKNIRKK 574
K + R + +S + R E P H H++ R S K + + + K
Sbjct: 723 ETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKH 782
Query: 575 TIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCS 634
K K + + L G V E R +SD+ +++ D S
Sbjct: 783 KQDTKSDSPRLKSER--AEALKQRPDGRSV--SESLRRDHDNKQKSDDRGESERHRGDQS 838
Query: 635 RSTR------SSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKT---SVLEESG 685
R R SS+NE I + + K + + + SGE K+ S + G
Sbjct: 839 RVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQG 898
Query: 686 PSRLNNNYLMSGKNDV--DDEEVHGSSDDSKQSKVIPKNR 723
S + + + K+ DD+ G+ +K P N+
Sbjct: 899 DSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNK 938
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 50.8 bits (120), Expect = 6e-06
Identities = 141/700 (20%), Positives = 253/700 (36%), Gaps = 105/700 (15%)
Query: 71 IQSPSKECQKSHPKSVPVS--------SKKKEASLQFVVEPSEATNRSVQAHEVHQKILA 122
+QS S C S P+ VP +KK+ ++ + E + +K
Sbjct: 297 LQSQSLPC--SSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQS----------EKAAM 344
Query: 123 TDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQ--- 179
D+ S + DS K++ R S+ D++ + G + ++VS+N IP + Q
Sbjct: 345 YDIISSPSKDSTKLTLRLSRVRSSDMDQQEDMISGVEN------SNVSENDIPFNVQYPG 398
Query: 180 -KRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERK 238
+T +N P + + +++ F + ++ + V+ ++ +TS Q ++
Sbjct: 399 QTSKTPITPQDINR-PLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQ 457
Query: 239 PSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKL 298
S Q I D E++ A L ++R S I R +
Sbjct: 458 QI-SQQGPIYD---EVELDA--------LAEIERIERESAIERERFSKE----------- 494
Query: 299 IEDEFIIDESDQSFASRSWITIPRKAGSL-------KQRTISPAEST--ALLQGRKSREK 349
+ + D+ R + P++AG Q T S + AL+ +
Sbjct: 495 ------VQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQA 548
Query: 350 HHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGE---TVNNYRSTKYEMYSKN 406
++ D S K P E Q +D V ++G T N+ T K
Sbjct: 549 GRVDSQASITQDSDSIKK-PEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP-----KK 602
Query: 407 AEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHE 466
P SK +KQ + R +KP E +L +S + + T TQ E + ++ E +
Sbjct: 603 KSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTECK 662
Query: 467 EMGNDCVSKKQ-------MPPVGSK----KSSTRKDKEESKKKRFSSESKNKLVPEEVTS 515
+ + V KQ P +K +S T K + E+ K++ S + +
Sbjct: 663 QNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHP 722
Query: 516 TVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMH-HNSSRKSTKKTNQSSKNIRKK 574
K + R + +S + R E P H H++ R S K + + + K
Sbjct: 723 ETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKH 782
Query: 575 TIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCS 634
K K + + L G V E R +SD+ +++ D S
Sbjct: 783 KQDTKSDSPRLKSER--AEALKQRPDGRSV--SESLRRDHDNKQKSDDRGESERHRGDQS 838
Query: 635 RSTR------SSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKT---SVLEESG 685
R R SS+NE I + + K + + + SGE K+ S + G
Sbjct: 839 RVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQG 898
Query: 686 PSRLNNNYLMSGKNDV--DDEEVHGSSDDSKQSKVIPKNR 723
S + + + K+ DD+ G+ +K P N+
Sbjct: 899 DSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNK 938
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 48.9 bits (115), Expect = 2e-05
Identities = 126/658 (19%), Positives = 240/658 (36%), Gaps = 105/658 (15%)
Query: 202 KTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKS 261
KTK++ D + KK I ++K +ER P + E K S
Sbjct: 984 KTKRKN--DGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSS 1041
Query: 262 FSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIP 321
S+ E K +P H+ +A H +TK +++E + + + S T
Sbjct: 1042 SSSQKDE----KITGTPRKAHSKSAKEHQ----ETKPVKEEKVKKDYSKDVKSEKLTTKE 1093
Query: 322 RKAGSLKQRTISPAESTALLQGRKSREK--------------------------HHNILP 355
KA ++ P ++ + RK+ EK + P
Sbjct: 1094 EKAKKPNEKN-KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEP 1152
Query: 356 KTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKR 415
T D+ K + S P+ K L+ + N +TK + +
Sbjct: 1153 DTEKMDRTPEKDK-ISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1211
Query: 416 TIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNM-EEHEEMGNDCVS 474
+K K RRK V + + S + + E + ++ R + + EE ND +
Sbjct: 1212 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTA 1271
Query: 475 KKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVK 534
+ + + ++ DK++ + + +S + ++V K+ +S +PS+
Sbjct: 1272 PAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKN--VSTKPSNIVKYP 1329
Query: 535 SEESPV----------YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTA 584
+ES S+ +++E+ NS+ KT ++ +K P KR+ +
Sbjct: 1330 EKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNST 1389
Query: 585 TKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNED 644
+ LN +G+ +S+ S E SD+ D STR+S N+D
Sbjct: 1390 QPEKESNLDRLNEQGN-----FKSLSQSS-KEARTSDKHD-----------STRASSNKD 1432
Query: 645 NIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTS---------VLEESGPSRLNNNYLM 695
+T N +++ D+ E+ +S + PSR N
Sbjct: 1433 ----------------FTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR--NKDSA 1474
Query: 696 SGKNDVDDEE---VHGSSDDSKQSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLE 749
SG+ + EE + DSK+S P + HK + PN TK P +
Sbjct: 1475 SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPN-EETKSVDKNPCK 1533
Query: 750 YWRGERIDYQ-GRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLDNDER 806
++ + + S G + +L+P ++ + ++ G+++K + K + L + R
Sbjct: 1534 DREKHVLEARNNKESSGNKLLYILNPP--ETQVEKEQITGQIDKSTVKPKPQLSHSSR 1589
Score = 46.2 bits (108), Expect = 1e-04
Identities = 122/624 (19%), Positives = 221/624 (35%), Gaps = 111/624 (17%)
Query: 43 EEKSLANDFSTNSTKSV---------PNSTRKIK-DT------------CIQSPSKECQK 80
EEK + DF ++S K P+ RK++ DT + +P+K+ +
Sbjct: 1118 EEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKL 1177
Query: 81 SHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEV----HQKILATDVSSKNTPDSKKI 136
+ + S + ++ + E E+T+ V+ +V +K+ T+ SS D
Sbjct: 1178 NRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTST 1237
Query: 137 SS-----------------------RNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNV 173
SS N+ ++ E+ + + P D S+
Sbjct: 1238 SSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEE 1297
Query: 174 IPSSAQKRETYTFENSV--NMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKT 231
S Q + SV N+ + + +K +K+ ++ +++ E K+
Sbjct: 1298 DVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKS 1357
Query: 232 SEGQERKPSGSSQNRIRDS-EYEIQRQAKKSFSTLFLETVKRKSES------SPIVRHAA 284
S+ G +++R E E + K S + R +E S + A
Sbjct: 1358 SKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEAR 1417
Query: 285 TAPPHSCPPDDTKLIEDEFIIDESDQS--FASRSWITIPRK--AGSLKQRTISPAESTAL 340
T+ H D T+ ++ D+ + +R + + R+ L +R SP+ +
Sbjct: 1418 TSDKH----DSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1473
Query: 341 LQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSD-KTVLDTSYALIGETVNNYRSTK 399
G+K++ + LPK D P +P D K DT + N +
Sbjct: 1474 ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDT------KRPNEETKSV 1527
Query: 400 YEMYSKNAEKPSRSKRTIKQKQRRK--FMAKPAEEQLDVGQ-----------SKDENIHT 446
+ K+ EK R K+ K ++ P E Q++ Q K + H+
Sbjct: 1528 DKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHS 1587
Query: 447 SHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKN 506
S ++ D R +D E + +D S + KEE S + K+
Sbjct: 1588 SRLSSD-LTRETDEAAFEPDYNESDSESNVSV-------------KEEESSGNISKDLKD 1633
Query: 507 KLV---PEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNS-----SR 558
K+V E + + ISR S SP S+S ++ H +S S+
Sbjct: 1634 KIVEKAKESLDTAAVVQVGISRNQSH---SSPSVSPSRSHSPSGSQTRSHSSSASSAESQ 1690
Query: 559 KSTKKTNQSSKNIRKKTIPLKRQK 582
S KK + K KK K+ K
Sbjct: 1691 DSKKKKKKKEKKKHKKHKKHKKHK 1714
Score = 44.3 bits (103), Expect = 5e-04
Identities = 110/607 (18%), Positives = 226/607 (37%), Gaps = 83/607 (13%)
Query: 221 DNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIV 280
DN S E++ E P N+ + + + + F L RKS V
Sbjct: 878 DNTKSKEKES-----ENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGV 932
Query: 281 RHAATAPPHSCPP-DDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTA 339
T P DD + DE +D +F S + K + + + + T
Sbjct: 933 EENKTDSLFVLPSRDDATPVRDE-PMDAESITFKS-----VSEKDKRERDKPKAKGDKTK 986
Query: 340 LLQGRKSREKHHNIL-----PKTLANDKHSHKPH---PVETSQPSDKTVLDTSYALIGET 391
+ K NI+ P+ + + P P++ ++ +T + +
Sbjct: 987 RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK 1046
Query: 392 VNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQ 451
T + +SK+A++ +K ++K ++ + SKD +
Sbjct: 1047 DEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY-------------SKDVKSEKLTTKE 1093
Query: 452 DEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPE 511
++ ++ +++N K + G K+ RK +E+ K F S S K+
Sbjct: 1094 EKAKKPNEKN--------------KPLDNKGEKRK--RKTEEKGVDKDFESSSM-KISKL 1136
Query: 512 EVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRK-----STKKTNQ 566
EVT V S + P + ++ E S S+ ++ ++ + +K + T +
Sbjct: 1137 EVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKE 1196
Query: 567 SSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGG-IVGHDEISRCSLSEPLESDEADL 625
S+ + + +K++K KG R +K EGS +V + S S +S+E
Sbjct: 1197 PSEKLESTSSKVKQEK--VKGKVR-RKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTD 1253
Query: 626 AKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESG 685
K+ + T N DN A++V + Q + + + T + G
Sbjct: 1254 TKRTVI----KTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVG 1309
Query: 686 -PSRLNNNYLMSGKNDV--DDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKR 742
P+ + N N V ++E S K +K + I H++ ++ N +++
Sbjct: 1310 KPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEV---KSSKNSASSEK 1366
Query: 743 TRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLD 802
+ K +Y E+ + + R + S++ + + N+ ++N++ N K +
Sbjct: 1367 GKTKDRDYSVLEKENPEKRKN--------------STQPEKESNLDRLNEQGNFKSLSQS 1412
Query: 803 NDERKTN 809
+ E +T+
Sbjct: 1413 SKEARTS 1419
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 48.9 bits (115), Expect = 2e-05
Identities = 126/658 (19%), Positives = 240/658 (36%), Gaps = 105/658 (15%)
Query: 202 KTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKS 261
KTK++ D + KK I ++K +ER P + E K S
Sbjct: 1018 KTKRKN--DGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSS 1075
Query: 262 FSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIP 321
S+ E K +P H+ +A H +TK +++E + + + S T
Sbjct: 1076 SSSQKDE----KITGTPRKAHSKSAKEHQ----ETKPVKEEKVKKDYSKDVKSEKLTTKE 1127
Query: 322 RKAGSLKQRTISPAESTALLQGRKSREK--------------------------HHNILP 355
KA ++ P ++ + RK+ EK + P
Sbjct: 1128 EKAKKPNEKN-KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEP 1186
Query: 356 KTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKR 415
T D+ K + S P+ K L+ + N +TK + +
Sbjct: 1187 DTEKMDRTPEKDK-ISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1245
Query: 416 TIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNM-EEHEEMGNDCVS 474
+K K RRK V + + S + + E + ++ R + + EE ND +
Sbjct: 1246 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTA 1305
Query: 475 KKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVK 534
+ + + ++ DK++ + + +S + ++V K+ +S +PS+
Sbjct: 1306 PAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKN--VSTKPSNIVKYP 1363
Query: 535 SEESPV----------YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTA 584
+ES S+ +++E+ NS+ KT ++ +K P KR+ +
Sbjct: 1364 EKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNST 1423
Query: 585 TKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNED 644
+ LN +G+ +S+ S E SD+ D STR+S N+D
Sbjct: 1424 QPEKESNLDRLNEQGN-----FKSLSQSS-KEARTSDKHD-----------STRASSNKD 1466
Query: 645 NIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTS---------VLEESGPSRLNNNYLM 695
+T N +++ D+ E+ +S + PSR N
Sbjct: 1467 ----------------FTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR--NKDSA 1508
Query: 696 SGKNDVDDEE---VHGSSDDSKQSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLE 749
SG+ + EE + DSK+S P + HK + PN TK P +
Sbjct: 1509 SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPN-EETKSVDKNPCK 1567
Query: 750 YWRGERIDYQ-GRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLDNDER 806
++ + + S G + +L+P ++ + ++ G+++K + K + L + R
Sbjct: 1568 DREKHVLEARNNKESSGNKLLYILNPP--ETQVEKEQITGQIDKSTVKPKPQLSHSSR 1623
Score = 46.2 bits (108), Expect = 1e-04
Identities = 122/624 (19%), Positives = 221/624 (35%), Gaps = 111/624 (17%)
Query: 43 EEKSLANDFSTNSTKSV---------PNSTRKIK-DT------------CIQSPSKECQK 80
EEK + DF ++S K P+ RK++ DT + +P+K+ +
Sbjct: 1152 EEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKL 1211
Query: 81 SHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEV----HQKILATDVSSKNTPDSKKI 136
+ + S + ++ + E E+T+ V+ +V +K+ T+ SS D
Sbjct: 1212 NRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTST 1271
Query: 137 SS-----------------------RNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNV 173
SS N+ ++ E+ + + P D S+
Sbjct: 1272 SSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEE 1331
Query: 174 IPSSAQKRETYTFENSV--NMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKT 231
S Q + SV N+ + + +K +K+ ++ +++ E K+
Sbjct: 1332 DVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKS 1391
Query: 232 SEGQERKPSGSSQNRIRDS-EYEIQRQAKKSFSTLFLETVKRKSES------SPIVRHAA 284
S+ G +++R E E + K S + R +E S + A
Sbjct: 1392 SKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEAR 1451
Query: 285 TAPPHSCPPDDTKLIEDEFIIDESDQS--FASRSWITIPRK--AGSLKQRTISPAESTAL 340
T+ H D T+ ++ D+ + +R + + R+ L +R SP+ +
Sbjct: 1452 TSDKH----DSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1507
Query: 341 LQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSD-KTVLDTSYALIGETVNNYRSTK 399
G+K++ + LPK D P +P D K DT + N +
Sbjct: 1508 ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDT------KRPNEETKSV 1561
Query: 400 YEMYSKNAEKPSRSKRTIKQKQRRK--FMAKPAEEQLDVGQ-----------SKDENIHT 446
+ K+ EK R K+ K ++ P E Q++ Q K + H+
Sbjct: 1562 DKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHS 1621
Query: 447 SHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKN 506
S ++ D R +D E + +D S + KEE S + K+
Sbjct: 1622 SRLSSD-LTRETDEAAFEPDYNESDSESNVSV-------------KEEESSGNISKDLKD 1667
Query: 507 KLV---PEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNS-----SR 558
K+V E + + ISR S SP S+S ++ H +S S+
Sbjct: 1668 KIVEKAKESLDTAAVVQVGISRNQSH---SSPSVSPSRSHSPSGSQTRSHSSSASSAESQ 1724
Query: 559 KSTKKTNQSSKNIRKKTIPLKRQK 582
S KK + K KK K+ K
Sbjct: 1725 DSKKKKKKKEKKKHKKHKKHKKHK 1748
Score = 44.3 bits (103), Expect = 5e-04
Identities = 110/607 (18%), Positives = 226/607 (37%), Gaps = 83/607 (13%)
Query: 221 DNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIV 280
DN S E++ E P N+ + + + + F L RKS V
Sbjct: 912 DNTKSKEKES-----ENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGV 966
Query: 281 RHAATAPPHSCPP-DDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTA 339
T P DD + DE +D +F S + K + + + + T
Sbjct: 967 EENKTDSLFVLPSRDDATPVRDE-PMDAESITFKS-----VSEKDKRERDKPKAKGDKTK 1020
Query: 340 LLQGRKSREKHHNIL-----PKTLANDKHSHKPH---PVETSQPSDKTVLDTSYALIGET 391
+ K NI+ P+ + + P P++ ++ +T + +
Sbjct: 1021 RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK 1080
Query: 392 VNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQ 451
T + +SK+A++ +K ++K ++ + SKD +
Sbjct: 1081 DEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDY-------------SKDVKSEKLTTKE 1127
Query: 452 DEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPE 511
++ ++ +++N K + G K+ RK +E+ K F S S K+
Sbjct: 1128 EKAKKPNEKN--------------KPLDNKGEKRK--RKTEEKGVDKDFESSSM-KISKL 1170
Query: 512 EVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRK-----STKKTNQ 566
EVT V S + P + ++ E S S+ ++ ++ + +K + T +
Sbjct: 1171 EVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKE 1230
Query: 567 SSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGG-IVGHDEISRCSLSEPLESDEADL 625
S+ + + +K++K KG R +K EGS +V + S S +S+E
Sbjct: 1231 PSEKLESTSSKVKQEK--VKGKVR-RKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTD 1287
Query: 626 AKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESG 685
K+ + T N DN A++V + Q + + + T + G
Sbjct: 1288 TKRTVI----KTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVG 1343
Query: 686 -PSRLNNNYLMSGKNDV--DDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKR 742
P+ + N N V ++E S K +K + I H++ ++ N +++
Sbjct: 1344 KPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEV---KSSKNSASSEK 1400
Query: 743 TRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLD 802
+ K +Y E+ + + R + S++ + + N+ ++N++ N K +
Sbjct: 1401 GKTKDRDYSVLEKENPEKRKN--------------STQPEKESNLDRLNEQGNFKSLSQS 1446
Query: 803 NDERKTN 809
+ E +T+
Sbjct: 1447 SKEARTS 1453
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 48.1 bits (113), Expect = 4e-05
Identities = 85/417 (20%), Positives = 162/417 (38%), Gaps = 35/417 (8%)
Query: 178 AQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQER 237
A K ++F + P T +T R + K LKK E K DE+ T ++
Sbjct: 73 AHKWIRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEY-KKSKDEKGGTPLKKDS 131
Query: 238 KPSGSSQNRIRDSEYEIQRQAKK-----------SFSTLFLETVKRKSESSPIVRHAATA 286
K G S +S+ ++ + K+ S + K SE++P +++ T
Sbjct: 132 KKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTV 191
Query: 287 PPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKS 346
+ C D K D + + ++ +R+ + + + + S
Sbjct: 192 SKN-CSQKDKK--------DSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENS 242
Query: 347 REKHHNILPKTLANDKHSHKPHPVETSQPSDK--TVLDTSYALIGETVNNYRSTKYEMY- 403
+L ++ + SQ + K ++ T Y N +S+ E
Sbjct: 243 LNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESED 302
Query: 404 SKNAEKPSRS-KRTIKQKQRRKFMAKPAEE-QLDVGQSKDENIHTSH----ITQDEFQRN 457
SK+A+K S+ K+ +K+ ++K + K E + G SKDE T + +D+ +++
Sbjct: 303 SKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKD 362
Query: 458 SDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTV 517
+ + E + D + K S K+++KK FS++S+++L +E
Sbjct: 363 TKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDE 422
Query: 518 TKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKK 574
K ++ S+ + V EES + +E +K KK + SK KK
Sbjct: 423 KKDKKDSKTDNKKSVKNDEES-----TDADSEPKGDSKKGKKDEKKGKKDSKKDDKK 474
Score = 47.4 bits (111), Expect = 6e-05
Identities = 97/511 (18%), Positives = 188/511 (36%), Gaps = 47/511 (9%)
Query: 43 EEKSLANDFSTN-STKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVV 101
+ K ++TN +K + K ++ ++P K ++ SS + Q
Sbjct: 130 DSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSK 189
Query: 102 EPSEATNRSVQAHEVHQKILATD-VSSKNTPDSKKISSRNINDHHSEADEE------FYL 154
S+ ++ + + K T+ + +KN P S+ ND SE E F +
Sbjct: 190 TVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLM 249
Query: 155 SVGSP---SVLLDA-KTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFD 210
VG S+ DA + SQN + + K YT +++ S++ + K D
Sbjct: 250 LVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKD 309
Query: 211 DKVMLKKIEIDNKVSD-EEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLET 269
K + K ++ D+K D ++D S E S + + + ++++ KK + + E+
Sbjct: 310 SKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPES 369
Query: 270 VKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQ 329
+S + R+ + + DD K K+
Sbjct: 370 TDTESGDAKDARNDSRNLKKASKNDD---------------------------KKKDAKK 402
Query: 330 RTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIG 389
T S +S + L+ ++S++ + ++K S K E S +D S
Sbjct: 403 ITFS-TDSESELESKESQKDEKKDKKDSKTDNKKSVKND--EESTDADSEPKGDSKKGKK 459
Query: 390 ETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHI 449
+ + +K + K+A+K + S + +K E++ K + +
Sbjct: 460 DEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTES 519
Query: 450 TQDEFQRNSDRNMEEHEEM-GNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKL 508
T EF +S + ++ G+D S++ + G+KK D + K ESK
Sbjct: 520 TDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGF 579
Query: 509 VPEEVTSTVTKSRRISRRPSDWWVVKSEESP 539
++S T + S V S E P
Sbjct: 580 ---RMSSKKTTFNEKGEKASTGRVPPSREKP 607
Score = 43.1 bits (100), Expect = 0.001
Identities = 79/377 (20%), Positives = 136/377 (36%), Gaps = 80/377 (21%)
Query: 336 ESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNY 395
ES +++ + R+ + P K SH+ + S+ S +T ++ + +TV+
Sbjct: 143 ESKQIVEEKTKRQNEADKTPL-----KSSHENEQSKKSKSSSETNPESQNS---KTVSKN 194
Query: 396 RSTKYEMYSKNAEKPSRS-----KRTIKQKQRRKFMAKPAEEQLD-----------VGQS 439
S K + SKN++K + K +R K P E VGQS
Sbjct: 195 CSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQS 254
Query: 440 KDENI-----------------------HTSHITQDEFQRNSDRNMEEHEEMGNDCVSKK 476
DE+I +T T+ +++SD E+ ++ D K
Sbjct: 255 DDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVK 314
Query: 477 QMPPVGSKKSSTRKD-----------KEESK-----KKRFSSESKNKLVPEEVTSTVTK- 519
+ KK +KD K+E K KK+ + K K + ST T+
Sbjct: 315 KNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTES 374
Query: 520 ---------SRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKN 570
SR + + + K + +S S E + S+K KK + SK
Sbjct: 375 GDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDS---ESELESKESQKDEKKDKKDSKT 431
Query: 571 IRKKTIPLKRQKT----ATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLA 626
KK++ + T KG+ + K +G D+ + E+DL
Sbjct: 432 DNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLE 491
Query: 627 KKKNLDCSRSTRSSKNE 643
KK+ S+ + SK +
Sbjct: 492 LKKDKKHSKEKKGSKKD 508
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 46.6 bits (109), Expect = 1e-04
Identities = 56/259 (21%), Positives = 102/259 (39%), Gaps = 14/259 (5%)
Query: 346 SREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDT-----SYALIGETVNNYRSTKY 400
SRE+H + KHS V S TV+ + +T ++ + K
Sbjct: 32 SRERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKL 91
Query: 401 EMYSKNAEKPS-RSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHT-SHITQDEFQRNS 458
+ + + S RS R K + + ++ + + K + + + S +D +S
Sbjct: 92 DRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
Query: 459 DRNMEEHEEMGNDCVSKKQMPPVGSKK---SSTRKDKEESKKKRFSSESKNKLVPEEVTS 515
R+ EE ++ G V+K S K TRK++E + S+S K +
Sbjct: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYK 211
Query: 516 TVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPM----HHNSSRKSTKKTNQSSKNI 571
TV +R SR P W S++ S +S + + H SS + K + S +
Sbjct: 212 TVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSR 271
Query: 572 RKKTIPLKRQKTATKGNQR 590
R+ P ++ +A + + R
Sbjct: 272 RQSVSPPYKEPSAYQSSTR 290
Score = 33.9 bits (76), Expect = 0.73
Identities = 70/343 (20%), Positives = 119/343 (34%), Gaps = 47/343 (13%)
Query: 340 LLQGRKSREKHHNILP-----KTLANDKH-SHKPHPV-ETSQPSDKTVLDTSYALIGETV 392
L G K R K H KT+ + K S PH S D + SY +
Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLS 249
Query: 393 --NNYRSTKYEMYSKNAEKPSR----------------SKRTIKQKQRRKFMAKPAEEQL 434
++ S+ Y+ Y K+ SR S R+ RR+ P +
Sbjct: 250 PSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRR 309
Query: 435 DVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEE 494
+ + + +R+S + + + S+K M + +R
Sbjct: 310 SSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSH 369
Query: 495 SKKKRFSSESKNKLV-PEEVTSTVTKSRRISRRPSDWWVV---------KSEESPVYSNS 544
SKKKR SS S++ + P + + +SR+ + +S+ SPV+
Sbjct: 370 SKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVF--- 426
Query: 545 SVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIV 604
LP NSS ++ +S K R + T + + G V
Sbjct: 427 -----LPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKV 481
Query: 605 GHDEISRCSLSEPLES----DEADLAKKKNLDCSRSTRSSKNE 643
DE S L + L++ D +A K+ + + T +S+ E
Sbjct: 482 KLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKE 524
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 46.6 bits (109), Expect = 1e-04
Identities = 56/259 (21%), Positives = 102/259 (39%), Gaps = 14/259 (5%)
Query: 346 SREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDT-----SYALIGETVNNYRSTKY 400
SRE+H + KHS V S TV+ + +T ++ + K
Sbjct: 32 SRERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKL 91
Query: 401 EMYSKNAEKPS-RSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHT-SHITQDEFQRNS 458
+ + + S RS R K + + ++ + + K + + + S +D +S
Sbjct: 92 DRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
Query: 459 DRNMEEHEEMGNDCVSKKQMPPVGSKK---SSTRKDKEESKKKRFSSESKNKLVPEEVTS 515
R+ EE ++ G V+K S K TRK++E + S+S K +
Sbjct: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYK 211
Query: 516 TVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPM----HHNSSRKSTKKTNQSSKNI 571
TV +R SR P W S++ S +S + + H SS + K + S +
Sbjct: 212 TVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSR 271
Query: 572 RKKTIPLKRQKTATKGNQR 590
R+ P ++ +A + + R
Sbjct: 272 RQSVSPPYKEPSAYQSSTR 290
Score = 33.9 bits (76), Expect = 0.73
Identities = 70/343 (20%), Positives = 119/343 (34%), Gaps = 47/343 (13%)
Query: 340 LLQGRKSREKHHNILP-----KTLANDKH-SHKPHPV-ETSQPSDKTVLDTSYALIGETV 392
L G K R K H KT+ + K S PH S D + SY +
Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLS 249
Query: 393 --NNYRSTKYEMYSKNAEKPSR----------------SKRTIKQKQRRKFMAKPAEEQL 434
++ S+ Y+ Y K+ SR S R+ RR+ P +
Sbjct: 250 PSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRR 309
Query: 435 DVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEE 494
+ + + +R+S + + + S+K M + +R
Sbjct: 310 SSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSH 369
Query: 495 SKKKRFSSESKNKLV-PEEVTSTVTKSRRISRRPSDWWVV---------KSEESPVYSNS 544
SKKKR SS S++ + P + + +SR+ + +S+ SPV+
Sbjct: 370 SKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVF--- 426
Query: 545 SVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIV 604
LP NSS ++ +S K R + T + + G V
Sbjct: 427 -----LPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKV 481
Query: 605 GHDEISRCSLSEPLES----DEADLAKKKNLDCSRSTRSSKNE 643
DE S L + L++ D +A K+ + + T +S+ E
Sbjct: 482 KLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKE 524
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 44.7 bits (104), Expect = 4e-04
Identities = 122/673 (18%), Positives = 243/673 (36%), Gaps = 98/673 (14%)
Query: 22 RARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKS 81
+ ++N E+G+ V E + EE++LA K T+ ++ + KE
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALA----WQREKLSEEETKLAQEEELLIQEKEKLAQ 1786
Query: 82 HPKSVPVSS----KKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKIS 137
H + +P +K+E ++ ++ ++ R + + E K KN KK
Sbjct: 1787 HKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKK-- 1844
Query: 138 SRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSST 197
+ A E+ L K ++ N + K++ +N + M
Sbjct: 1845 --------NLAQEK--------EKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMF---N 1885
Query: 198 EVSVKTKKRLNFDDKVMLKK----IEIDNKVSDEEDKTSEGQER-----------KPSGS 242
++ + +++L + + ++KK E + K+ ED ++ QE+ K
Sbjct: 1886 KILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQ 1945
Query: 243 SQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTK----- 297
+ R+R E +I ++ K L LE + E +V T P +
Sbjct: 1946 GKKRLR-GELDIAKEEK----ALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQ 2000
Query: 298 -----------------LIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTAL 340
L ED + E + + T ++ QR ++ A S L
Sbjct: 2001 VEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKA-SRKL 2059
Query: 341 LQGRKSREKHHNILPKTL------ANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNN 394
++ R+S K L K L D+ ++ ++ + I ++ +
Sbjct: 2060 IKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLD 2119
Query: 395 YR----STKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHIT 450
+ S K +K+ +K +R +R + K RR EE++ +SK H+ I
Sbjct: 2120 IKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINK---EEKMTEEESKLARKHSEVIL 2176
Query: 451 QDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVP 510
DE + +EE E + + ++ +K+ K+K S+ SE
Sbjct: 2177 DDE----EEGGIEEEEVI--PFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEM 2230
Query: 511 EEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKN 570
E + + K +S + + EE VR E K+ + +
Sbjct: 2231 ESLLDELEKQESLSSEEEE----EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286
Query: 571 IRKKTIPLKRQKTATKGN--QRVQKFLNAEGSGGIVGHDEISR-CSLSEPLESDEADLAK 627
+KK K+++ K + ++ ++ E + + +E CSL E ++ ++ L K
Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKK 2346
Query: 628 KKNLDCSRSTRSS 640
+K R S
Sbjct: 2347 EKQFKLQEQRRKS 2359
Score = 40.0 bits (92), Expect = 0.010
Identities = 69/415 (16%), Positives = 151/415 (36%), Gaps = 17/415 (4%)
Query: 165 AKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKV 224
AK + N+ + + E + T + + +K + ++ +K+ ++ K+
Sbjct: 1957 AKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKI 2016
Query: 225 SDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAA 284
ED+ +E + + R +Q Q K + ++ L + P +
Sbjct: 2017 LLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKI 2076
Query: 285 TAPPHSCPPDDTKLIEDEFIIDESDQS-FASRSWITIPRKAGSLKQRTISPAESTALLQG 343
D+ KL ++E + + ++ F ++I + +K+ S S
Sbjct: 2077 LKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDE 2136
Query: 344 RKSREKHHNILPKT--LANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYE 401
+K K + K + N + + ++ + +LD E
Sbjct: 2137 KKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDE-----EEGGIEEEEVIP 2191
Query: 402 MYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKD-ENIHTSHITQDEFQRNSDR 460
+ K +KR K K+ KF ++ E + + S++ E++ Q+ +
Sbjct: 2192 FLKRRWRKRKEAKRGDKPKE--KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEE 2249
Query: 461 NMEEHEEMGNDCVSKKQMPPVGSKKSSTRK-DKEESKKKRFSSESKNKLVPEEVTSTVTK 519
EE EE + V +++ ++ ++ +KEE +KK+ E K + V E+ K
Sbjct: 2250 EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK 2309
Query: 520 SRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHN--SSRKSTKKTNQSSKNIR 572
+S ++ S+E + S+ E+ K K Q K++R
Sbjct: 2310 EEIMSEEETE---SLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLR 2361
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 44.7 bits (104), Expect = 4e-04
Identities = 55/282 (19%), Positives = 104/282 (36%), Gaps = 4/282 (1%)
Query: 435 DVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEE 494
D S + + + D NS + + + +D S SS D +
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612
Query: 495 SKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHH 554
S SS+SK+ E S+ + S+ S + + +S SNSS ++
Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 555 NSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSL 614
+SS S+ + +S + + +++ + ++ S D S S
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 615 SEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSG 674
S+ +D + D S S+ SS + D+ ++ + + + ++SN S
Sbjct: 733 DSSDSSNSSD--SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790
Query: 675 EHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQS 716
+S + S S +N+ S +D D + SSD S S
Sbjct: 791 SSDSS--DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Score = 43.9 bits (102), Expect = 7e-04
Identities = 67/308 (21%), Positives = 121/308 (39%), Gaps = 32/308 (10%)
Query: 430 AEEQLDVGQSKDENIHTSH----ITQDEFQRNSDRNMEEHEE--MGNDCVSKKQMPPVGS 483
A+E D G DE+ + + Q D E+ + +G + SK+ P G
Sbjct: 251 ADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGK 310
Query: 484 KKSSTRKDKEESKKKRFSSESKNKLVPEE-----VTSTVTKSRRISRRPSDWWVVKSEES 538
+ D +++ K SE + +PE+ + T + R S+R + +SE
Sbjct: 311 EDPHNEVDGDKTSK----SEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETH 366
Query: 539 PVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQ-KFLNA 597
V + E+ + +R TK+ + ++ K + KGN + Q + +N
Sbjct: 367 AVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKG---QHGMILGKGNVKTQGEVVNI 423
Query: 598 EGSG------GIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQN 651
EG G VGH S S+ +S + D + D + S S+ N+D + N
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDN 483
Query: 652 VPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGK----NDVDD--EE 705
+ Y + ++ N + + K + ++S + NN +G ND +D +
Sbjct: 484 NSSSRGDASYNSD-ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542
Query: 706 VHGSSDDS 713
G SD S
Sbjct: 543 GKGKSDSS 550
Score = 39.7 bits (91), Expect = 0.013
Identities = 93/497 (18%), Positives = 163/497 (32%), Gaps = 38/497 (7%)
Query: 221 DNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIV 280
D+ SD D S + S S + DS+ + S + S+SS
Sbjct: 565 DSSDSDSSDSNSSS-DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 281 RHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTAL 340
++ + S D D D SD S +S S S + ++S+
Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS---------SNSSNSSDSSDSSDS 674
Query: 341 LQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKY 400
S + ++ ++ +S E+S SD + D+S ++ ++ S
Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSS-----ESSDSSDSSDSDSS-----DSSDSSNSNSS 724
Query: 401 EMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDE-NIHTSHITQDEFQRNSD 459
+ S N+ S S + + + D S D N S + D +
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSD-----SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 460 RNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTK 519
N + + N S S SS D +S S+ S + + S+ +
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 520 SRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLK 579
S SD S SNSS ++ NSS S + S N +
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS---- 895
Query: 580 RQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRS 639
++ + N+ S + S S S SD ++ + N S +
Sbjct: 896 --DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS----SDNSNSSDSSNSSDSSDSSD 949
Query: 640 SKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKN 699
S N + + + +S + ++S+ S +S +S S ++N S +
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN--SSDSS 1007
Query: 700 DVDDEEVHGSSDDSKQS 716
D D +S DS S
Sbjct: 1008 DSSDSSDSSNSSDSSNS 1024
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 44.7 bits (104), Expect = 4e-04
Identities = 85/382 (22%), Positives = 150/382 (39%), Gaps = 58/382 (15%)
Query: 323 KAGSLKQR-----TISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSD 377
K LKQR ++ PA L + R++ P+ + H KP VE+ +
Sbjct: 531 KQTKLKQRADSRESLKPAAKP--LPSKSVRKESKEETPE-VTKVNHVEKPPKVESKE--- 584
Query: 378 KTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVG 437
K ++ + ET + T+ E+ SK E+PS K + +KQ K A+E+
Sbjct: 585 KVMVKKDKPIKTETKPSV--TEKEVPSK--EEPSPVKAEVAEKQATDVKPKAAKEKTVKK 640
Query: 438 QSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKK 497
++K + +D+ + E ++ + K++ P K +K+ ++ +K
Sbjct: 641 ETKVK-------PEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEK 693
Query: 498 KRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSS 557
K E K + P+EV V K + V K E+ P + E+ +
Sbjct: 694 KEPKKEVKKETPPKEVKKEVKKEEKKE-------VKKEEKEP-------KKEIKKLPKDA 739
Query: 558 RKSTKKTNQSSK------NIRKKTIPLKRQKTAT-----KGNQRVQKFLN--AEGSGGIV 604
+KS+ +++ K + KK +K+ A KG +V K AE V
Sbjct: 740 KKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAV 799
Query: 605 GHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCN 664
G + ++ + A + K L+ RS SS + +T LK + T +
Sbjct: 800 GTGATTAAVMA---AAGIAAIGPAKELEAERSLMSSPED---LTKDFEELKAEEVDVTKD 853
Query: 665 IPTESNLDSGEHKTSVLEESGP 686
I + L E K L+E+ P
Sbjct: 854 IKPQLELIEDEEK---LKETEP 872
Score = 41.6 bits (96), Expect = 0.004
Identities = 102/504 (20%), Positives = 180/504 (35%), Gaps = 70/504 (13%)
Query: 57 KSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEAT----NRSVQ 112
K +S +K PSK +K + P +K VE E ++ ++
Sbjct: 536 KQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIK 595
Query: 113 AHEVHQKILATDVSSKNTPDSKK--ISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVS 170
E + +V SK P K ++ + D +A +E +V + K
Sbjct: 596 T-ETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKE-------KTVKKETKVKPE 647
Query: 171 QNVIPSSAQKRETYTFENSVNML----PSSTEVSVKTKKRLNFDDKVMLKKI-------- 218
K+E E+ + P EV + KK + ++K KK
Sbjct: 648 DKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK 707
Query: 219 EIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTL--------FLETV 270
E+ +V EE K + +E++P + ++ + AKKS + L V
Sbjct: 708 EVKKEVKKEEKKEVKKEEKEPKKEIK--------KLPKDAKKSSTPLSEAKKPAALKPKV 759
Query: 271 KRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQR 330
+K ES V+ + A K+I+ E E+ + T
Sbjct: 760 PKKEES---VKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATT----------A 806
Query: 331 TISPAESTALLQGRKSREKHHNIL--PKTLANDKHSHKPHPVETS---QPSDKTVLDTSY 385
+ A A + K E +++ P+ L D K V+ + +P + + D
Sbjct: 807 AVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEK 866
Query: 386 ALIGETVNNYRSTKYEMYSKN-AEKPSRSKRTIK---QKQRRKFMAKPAEEQ--LDVGQS 439
E V Y K +K AE P T + + ++ +P E+Q D+ +
Sbjct: 867 LKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKF 926
Query: 440 KDE--NIHTSHITQDEFQRNSDRNMEEHEEMGND--CVSKKQMPPVGSKKSSTRKDKEES 495
+DE S T D ++ EE EE G + CVS + P ++S+ +
Sbjct: 927 EDEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYI 986
Query: 496 KKKRFSSESKNKLVPEEVTSTVTK 519
++KR S S + E++ + K
Sbjct: 987 REKRESVASGDDRAEEDMDEAIEK 1010
Score = 33.5 bits (75), Expect = 0.96
Identities = 43/227 (18%), Positives = 94/227 (41%), Gaps = 28/227 (12%)
Query: 641 KNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKND 700
++++ +M ++ P+K +T TE + S E + V E + + + K
Sbjct: 581 ESKEKVMVKKDKPIKTETKPSV----TEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEK 636
Query: 701 VDDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQG 760
+E +D K+ K PK + K TP +++ ++ + + ++ + I +
Sbjct: 637 TVKKETKVKPEDKKEEKEKPKKEVAKK---EDKTP-IKKEEKPKKEEVKKEVKKEIKKEE 692
Query: 761 RPSGGFVISGVLSPDTISS--KRKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPL 818
+ + P + K++ K+ + K K+ K+ L D +K++ PL
Sbjct: 693 KKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSS------TPL 746
Query: 819 GDPLQPTRVKD--PETREIILMDLV---RPQDTYQFFVKHGELKVYK 860
+ +P +K P+ E + D V +P++ G++KV K
Sbjct: 747 SEAKKPAALKPKVPKKEESVKKDSVAAGKPKE-------KGKIKVIK 786
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 44.7 bits (104), Expect = 4e-04
Identities = 124/643 (19%), Positives = 237/643 (36%), Gaps = 87/643 (13%)
Query: 4 SGLDHLKNGY--RRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLAND-FSTNSTKSVP 60
S H +N Y + R S I+++ G+ L+ ++ S+++ S++S K++
Sbjct: 723 SSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLH 782
Query: 61 NSTRKIKD--TCIQSPSKECQKSHPKSVPVSSKKKEASLQFV--VEPSEATNRSVQAHEV 116
+ K +D +C++ S+ S+ SS +++S+Q + E + + H
Sbjct: 783 SKYVKGRDRSSCVRKYSES-----RSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNK 837
Query: 117 HQKILATDVSS--KNTPDSKKISSR-NINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNV 173
+K + S + P SKK + + N++DH + + D++++ ++V
Sbjct: 838 QEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSK--WDSESNSERDV 895
Query: 174 I--------PSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNF---DDKVMLKKIEIDN 222
PSS ++ T ++ + +V TK N DD K +
Sbjct: 896 TKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRT 955
Query: 223 KVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRH 282
SD E S + + G Q S+ ++R+ K L+ K K +P +
Sbjct: 956 STSDSEGSCSNSENNR--GKPQKHKHGSKENLKREHTKKVKEK-LKGKKDKKHKAPKRKQ 1012
Query: 283 AAT-APPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRK------------------ 323
A PP ++ + I+D+ + ES + S + TI
Sbjct: 1013 AFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDT 1072
Query: 324 ---AGSLKQRT-------ISPA-----ESTALLQG-RKSREKHHNILPKTLANDKHSH-- 365
+ L Q T ISP E+ A LQ + E N + L D +
Sbjct: 1073 VTVSSDLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEIC 1132
Query: 366 -----KPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK 420
P VE + P LDT I + +T++ ++ S S+ + +
Sbjct: 1133 TPDRSSPAKVEETSPLGNARLDTPD--INIVLKQDMATEHPQAEVVKQESSMSESKVLGE 1190
Query: 421 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP 480
++ + + K E S I D+ + + +GN
Sbjct: 1191 VGKQDSSSASLASAGESTGKKEVAEKSQINL------IDKKWKPLQGVGNLAAPNAATSS 1244
Query: 481 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV 540
K T + + + R +SKNK+ P + V K+ R++RRP +++ES
Sbjct: 1245 AVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRP------RNQESSS 1298
Query: 541 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKT 583
+ R++ + SR +K +S R + R ++
Sbjct: 1299 DEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRS 1341
Score = 42.4 bits (98), Expect = 0.002
Identities = 136/739 (18%), Positives = 254/739 (34%), Gaps = 64/739 (8%)
Query: 62 STRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRS--VQAHEVHQK 119
S IK+T S + +K+ SK + S + ++RS +
Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710
Query: 120 ILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQ 179
LA+ S +P S+ S +DH + Y S+ S D + ++ + SS +
Sbjct: 711 SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSD----DGRR--AKRRLRSSGK 764
Query: 180 KRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDK---TSEGQE 236
K ++S + + VK + R + K + +D E+ T QE
Sbjct: 765 KNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQE 824
Query: 237 RKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDT 296
++ G + ++ E R +KS S K+++ + H + +
Sbjct: 825 KEKQGQMER--THNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLR---------NGS 873
Query: 297 KLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPK 356
K + + D S +T K S E+T+ + S E H + P
Sbjct: 874 KPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVS-EIHIKVKPT 932
Query: 357 T-------LANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEM---YSKN 406
T L +D + K TS + S G+ + +K + ++K
Sbjct: 933 TKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKK 992
Query: 407 AEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRN----- 461
++ + K+ K K ++ A + L+ G+ ++E I +TQ+ ++ N
Sbjct: 993 VKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIK 1052
Query: 462 ---MEEHEEMGNDCVSKKQMPPVGSKKSSTRKD------------KEESKKKRFSSESKN 506
++ + D K V S KD EE+ + +
Sbjct: 1053 DNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQNIQHVE 1112
Query: 507 KLVPEEVTSTV-TKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTN 565
+ VP V + T P K EE+ N+ R + P N K T
Sbjct: 1113 ESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNA--RLDTP-DINIVLKQDMATE 1169
Query: 566 QSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADL 625
+ K+ + K + ++ + +G G E++ S ++ L
Sbjct: 1170 HPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPL 1229
Query: 626 AKKKNLDCSRSTRSSKNEDNIMTAQNVP-LKPQTSGYTCNIPTESNLDSGEHKTSVLEES 684
NL + SS E ++T VP +KPQ G I +++ + G V + +
Sbjct: 1230 QGVGNLAAPNAATSSAVEVKVLT--TVPEMKPQ--GLRIEIKSKNKVRPGSLFDEVRKTA 1285
Query: 685 GPSRLNNNYLMSGKNDVD--DEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKR 742
+R N S D++ S +SK K+R + V S++ + R+
Sbjct: 1286 RLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSST 1345
Query: 743 TRLKPLEYWRGERIDYQGR 761
+ + Y R + R
Sbjct: 1346 SSYRSRSYSRSRSRGWYSR 1364
Score = 40.4 bits (93), Expect = 0.008
Identities = 77/430 (17%), Positives = 152/430 (35%), Gaps = 66/430 (15%)
Query: 175 PSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEG 234
P+ ++ ++ + +S + S +E+ + +R + +K+ + K + ++
Sbjct: 192 PTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNK 251
Query: 235 QERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPD 294
P G S+ + + + AK+ P+VR P PP
Sbjct: 252 HAMNPKGHSERSDTNEKRSVDSSAKRE---------------KPVVR------PEEIPP- 289
Query: 295 DTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNIL 354
+ E+ F++ + IP A + + S ++S ++GR + H
Sbjct: 290 ---VPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPR 346
Query: 355 PKTLA----NDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAE-- 408
++ + +D PH E Q + YR E +SK +
Sbjct: 347 SRSCSESDDDDSSETPPHWKEEMQ----------------RLRAYRPPSGEKWSKGDKLS 390
Query: 409 KPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEM 468
P S+ + +R D+ ++ H + + + ++H
Sbjct: 391 DPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRR 450
Query: 469 GNDCVSKKQMPP--VGSKKSSTRKDKEESKKKRFSSESKNKL----------VPEEVTST 516
++ + P + S KSSTR+ K ++R S S ++V S+
Sbjct: 451 HKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSS 510
Query: 517 VTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTI 576
+T S R S R S YS S R+ +S +S K+ SSK+ +K
Sbjct: 511 LTHSSRDSYR-------SKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRA 563
Query: 577 PLKRQKTATK 586
+KTA++
Sbjct: 564 SKSPRKTASQ 573
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 44.7 bits (104), Expect = 4e-04
Identities = 111/553 (20%), Positives = 196/553 (35%), Gaps = 77/553 (13%)
Query: 54 NSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQA 113
+ +KS+ K+ + ++C K+ P+S P S+ EPS
Sbjct: 374 HQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNS----------EPSHH------- 416
Query: 114 HEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNV 173
+S+ +S+ SS + S + S S S + S S
Sbjct: 417 ------------NSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
Query: 174 IPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSD-----EE 228
P K + + N VN S SV + + K ++ N +D E
Sbjct: 465 EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKET 524
Query: 229 DKTSEGQERKP--SGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATA 286
+ G++ K GS R R Q+ +S ST TV +K AA
Sbjct: 525 SSATPGRDSKTIQKGSESGRGR------QKSPAQSDSTTQRRTVGKKQPKK--AEKAAAE 576
Query: 287 PPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIP--RKAGSLKQRTISP---AESTALL 341
P IE E +D + +SR RK K+ SP AE
Sbjct: 577 EPRG-----GLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYK 631
Query: 342 QGRKSREKHHNILPK-TLANDKHSHKPHPVETSQP----SDKTVLDTSYALIGETVNNYR 396
KS +K I+ T ++D + P + P S++T + S + E + +R
Sbjct: 632 STSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS--VEEEDSFFR 689
Query: 397 STKY------EMYSKNAEKPSRSKRTIKQKQR--RKFMAKPAEEQLDVGQSKDENI---H 445
+ E+ S +E R +K + KP +E + + + +N+ H
Sbjct: 690 QRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKET-EPPKGEKKNVPEKH 748
Query: 446 TSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESK 505
T + ++ S++ +H+ ++ S+ + P K S+ K + + S+ +
Sbjct: 749 TREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKE 808
Query: 506 NKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTK--- 562
L+P +K + + +S SNS+ ++SS K
Sbjct: 809 KDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTE 868
Query: 563 -KTNQSSKNIRKK 574
KT+ SSK +++K
Sbjct: 869 GKTSSSSKEVKEK 881
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 44.3 bits (103), Expect = 5e-04
Identities = 67/347 (19%), Positives = 128/347 (36%), Gaps = 44/347 (12%)
Query: 393 NNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQD 452
+ + K E +N ++PS +R +K + P E G + H S +
Sbjct: 108 DKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRE----TGGKR----HESSSEKK 159
Query: 453 EFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEE 512
E + S + EE + SKK+ K+ T + +KR S + K EE
Sbjct: 160 ERKGYSPTHREEEYGKNHHNSSKKE-------KNKTENTRLGDNRKRLSERLEEKEDNEE 212
Query: 513 VTSTVTKSRRISRRPSDWWVVKSEESPVYS--------NSSVRNELPMHHNSSRKSTKKT 564
+ R++++ W+ + Y+ S+ E ++ S K +
Sbjct: 213 GVYDYENTGRMTQK----WIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSS 268
Query: 565 NQSSKNIRKKT--IPLKRQKTATKGNQRVQKFLNAEG--------SGGIVGHD-----EI 609
+Q +++ + T +PL+ +T + RV + ++EG SG + E
Sbjct: 269 SQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQ 328
Query: 610 SRCSLSEPLESDEADLAKKKNLDCSR--STRSSKNEDNIMTAQNVPLKPQTSGYTCNIPT 667
SR P DE + + D SR TR ++ TA + + G
Sbjct: 329 SRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGH 388
Query: 668 ESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSK 714
+ + DS H + ++ + + + S + D E H + D++
Sbjct: 389 QQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQ 435
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 43.9 bits (102), Expect = 7e-04
Identities = 74/328 (22%), Positives = 132/328 (40%), Gaps = 33/328 (10%)
Query: 323 KAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLD 382
K GS ++R+ S + S + +SR +H + K SH + S
Sbjct: 176 KPGSRRRRSYSRSRSHSR---SRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS 232
Query: 383 TSYALIGETVNNYRSTKYEMYSKNAEKP-SRSKRTIKQKQRRKFMAKPAEEQLD-VGQSK 440
S + + RS K + S + EK SRS K + + K A+ + D VG+ K
Sbjct: 233 RS-----RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 441 DENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRF 500
+ R+ +R +EE E+ G+ + Q + +S +R + R
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEE-EKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 501 SSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKS 560
S+SK+K + + ++SR SR KSE S S R+ +S +K
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRS-------KSERS--RKRGSKRDS--KAGSSKKKK 395
Query: 561 TKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRC-----SLS 615
+ T++S +++ +R+ ++ +QR G G ++ +R S S
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQR-----EGRGESENAGTNQETRSRSRSNSKS 450
Query: 616 EP-LESDEADLAKKKNLDCSRSTRSSKN 642
+P L S+ +K + SRS S++
Sbjct: 451 KPNLPSESRSRSKSASKTRSRSKSRSRS 478
Score = 32.0 bits (71), Expect = 2.8
Identities = 44/253 (17%), Positives = 84/253 (33%), Gaps = 18/253 (7%)
Query: 408 EKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEE 467
+KP +R + R ++ +S+ + +SH R+ R+ +
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 468 MGND-CVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRR 526
SKK+ SK+ S + K + S + + + KSR SR
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 527 PSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATK 586
S S S R++ R S + K++R+ R ++ +K
Sbjct: 295 KSK------------SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ-----SRSRSRSK 337
Query: 587 GNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNI 646
G R + ++ G S S +++ ++K+ SSK +
Sbjct: 338 GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKE 397
Query: 647 MTAQNVPLKPQTS 659
T ++ P S
Sbjct: 398 DTDRSQSRSPSRS 410
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 43.9 bits (102), Expect = 7e-04
Identities = 52/211 (24%), Positives = 90/211 (42%), Gaps = 26/211 (12%)
Query: 428 KPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEE-------HEEMGNDCVSKKQMPP 480
KP +++ D + K E H ++E + N +E N VSKK+ P
Sbjct: 535 KPKKKEKDKKEKKKEK----HKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590
Query: 481 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV 540
+ SK T + +EE K K S E K +L + K R+ +++S E P
Sbjct: 591 MKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVH------IIQSRE-PS 643
Query: 541 YSNSSVRNELPMHHNSSRKSTKKTNQS--SKNIRKKTIPLKRQKTATKGNQRVQKFLNAE 598
NS+ +E+ + + + ST + + + +RKK P + G+ +++ F ++E
Sbjct: 644 LKNSN-PDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSE 702
Query: 599 GSGGIVGHDEISRCSLSEPLESDEADLAKKK 629
S S SE E++ A +KKK
Sbjct: 703 SES-----SSESSSSDSEDSETEMAPKSKKK 728
Score = 32.3 bits (72), Expect = 2.1
Identities = 31/148 (20%), Positives = 56/148 (37%), Gaps = 6/148 (4%)
Query: 424 KFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNME---EHEEMGNDCVSKKQMPP 480
K +A P+ S D + T ++ QR ++ + HE++ +Q P
Sbjct: 478 KVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAA-LSQPQQNKP 536
Query: 481 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPS--DWWVVKSEES 538
+K K KE+ K+K E+K E K+ + S + +KS+
Sbjct: 537 KKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPP 596
Query: 539 PVYSNSSVRNELPMHHNSSRKSTKKTNQ 566
P Y + PM + R+ + N+
Sbjct: 597 PTYESEEEDKCKPMSYEEKRQLSLDINK 624
>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 43.9 bits (102), Expect = 7e-04
Identities = 68/313 (21%), Positives = 116/313 (37%), Gaps = 57/313 (18%)
Query: 212 KVMLKKI----EIDNKVSDEEDKTS------------EGQERKPSGSSQNRIRDSEYEIQ 255
KV+L+ + + NK+ +E D G +RK SS +R+R ++ +
Sbjct: 8 KVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEE 67
Query: 256 RQA-----KKSFS-TLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESD 309
Q K S TL + +K KS + + A P +L +EF D SD
Sbjct: 68 SQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSD 127
Query: 310 QSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHP 369
Q + T P Q S ES + +KS +K K SHK
Sbjct: 128 QQDITNGKKTSP-------QVKSSTHESRKHKKSKKSHKKKQK---------KRSHKKQK 171
Query: 370 VETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKP 429
+ +D T D+S ET + + + K+K R+K + KP
Sbjct: 172 KSKKEATDITA-DSSSEFSEET------------GASGTRKGKQPHKRKKKSRKKSLKKP 218
Query: 430 A---EEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEE---HEEMGNDCVSKKQMPPVGS 483
A E + + S D +S +++ + + R E H + N+ + ++
Sbjct: 219 ALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNW 278
Query: 484 KKSSTRKDKEESK 496
K ++ + E S+
Sbjct: 279 KVATDERSAESSE 291
>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 43.9 bits (102), Expect = 7e-04
Identities = 68/313 (21%), Positives = 116/313 (37%), Gaps = 57/313 (18%)
Query: 212 KVMLKKI----EIDNKVSDEEDKTS------------EGQERKPSGSSQNRIRDSEYEIQ 255
KV+L+ + + NK+ +E D G +RK SS +R+R ++ +
Sbjct: 8 KVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEE 67
Query: 256 RQA-----KKSFS-TLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESD 309
Q K S TL + +K KS + + A P +L +EF D SD
Sbjct: 68 SQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSD 127
Query: 310 QSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHP 369
Q + T P Q S ES + +KS +K K SHK
Sbjct: 128 QQDITNGKKTSP-------QVKSSTHESRKHKKSKKSHKKKQK---------KRSHKKQK 171
Query: 370 VETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKP 429
+ +D T D+S ET + + + K+K R+K + KP
Sbjct: 172 KSKKEATDITA-DSSSEFSEET------------GASGTRKGKQPHKRKKKSRKKSLKKP 218
Query: 430 A---EEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEE---HEEMGNDCVSKKQMPPVGS 483
A E + + S D +S +++ + + R E H + N+ + ++
Sbjct: 219 ALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNW 278
Query: 484 KKSSTRKDKEESK 496
K ++ + E S+
Sbjct: 279 KVATDERSAESSE 291
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 43.5 bits (101), Expect = 0.001
Identities = 45/186 (24%), Positives = 85/186 (45%), Gaps = 18/186 (9%)
Query: 202 KTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQE-RKPSGSSQNRI----RDSEY---E 253
+ +K+ +FD K++L K +I+ + +D+E T+E +E R+ Q+++ R EY E
Sbjct: 356 REQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKE 415
Query: 254 IQRQAKKSFSTLFLETVKRKSESS--------PIVRHAATAPPHSCPPDDTKLIEDEFII 305
IQR K L ++T ++ ++R + K+ E++F
Sbjct: 416 IQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQR 475
Query: 306 DESDQSFASRSWITIPRKAGSLK-QRTISPAESTALLQGRKSREKHHNILPKTLANDKHS 364
+ SD+ + + ++ L+ Q T+S A+ A K+RE K A+ +
Sbjct: 476 ERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERY 535
Query: 365 H-KPHP 369
H +PHP
Sbjct: 536 HVEPHP 541
>gi|67551265 transcription factor ELYS [Homo sapiens]
Length = 2266
Score = 43.5 bits (101), Expect = 0.001
Identities = 93/440 (21%), Positives = 173/440 (39%), Gaps = 62/440 (14%)
Query: 169 VSQNV-----IPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNK 223
VSQN+ + SA K T ++N+ VS KT+ R ++I+ N
Sbjct: 1700 VSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRG--------QRIQNVNV 1751
Query: 224 VSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHA 283
S +++ +++ K G S + EI ++ +S V+ S++ I +++
Sbjct: 1752 KSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSD-----VRGLSQNQQIPQNS 1806
Query: 284 ATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQG 343
T P + E I E+ S IT R++ LK S A+ +
Sbjct: 1807 VT------PRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKS---SQLLEPAVEET 1857
Query: 344 RKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALI---GETVNNYRSTKY 400
K K ++ +T K S + +Q S + + D + + + RST
Sbjct: 1858 TKKEVKVSSVTKRTPRRIKRSVE------NQESVEIINDLKVSTVTSPSRMIRKLRSTNL 1911
Query: 401 EMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHIT-QDEF----- 454
+ S+N K + KQ + + E +D N+ +S +T Q EF
Sbjct: 1912 DA-SENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAI 1970
Query: 455 --QRNSDRNMEEHEEMGNDCVS------KKQMPPVGSKKSSTRKDKEESKKKRFSSESKN 506
+R R + E++G+ V KK+ P + + + K E+ + K+
Sbjct: 1971 PRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKS 2030
Query: 507 KLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRK------- 559
LVP E S V S++ + ++ +S++ ++S S R + H ++ +
Sbjct: 2031 ILVPNEELSMVMSSKKKLTKKTE---SQSQKRSLHSVSEERTDEMTHKETNEQEERLLAT 2087
Query: 560 -STKKTNQSSKNIRKKTIPL 578
S K+++SS+ K I L
Sbjct: 2088 ASFTKSSRSSRTRSSKAILL 2107
>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
Length = 1844
Score = 43.1 bits (100), Expect = 0.001
Identities = 115/588 (19%), Positives = 229/588 (38%), Gaps = 56/588 (9%)
Query: 76 KECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKK 135
KEC+ P+SVPV S K + + E + + + HQ ++ ++N +
Sbjct: 80 KECKIKSPESVPVDSNKDCTTPLEMFSNVEFKKKRKRVNLSHQ---LNNIKTENEAPI-E 135
Query: 136 ISSRNINDHHSEADEEFYLSVGSPSVLLDAK--TSVSQNVIPSSAQKRETYTFENS--VN 191
ISS + + +S + +F S S SVL K +++N+ + +Q + +NS VN
Sbjct: 136 ISSDDSKEDYS-LNNDFVES--STSVLRYKKQVEVLAENIQDTKSQPNTMTSLQNSKKVN 192
Query: 192 MLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSE 251
+T+ K ++ D V L + + + K + ++ + +S RD+
Sbjct: 193 PKQGTTKNDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQMENTTSHANSRDNV 252
Query: 252 YEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDT--KLIEDEFIIDESD 309
E + + + E +K E+ V + C P +T ++++ + I ES+
Sbjct: 253 TEAAQLNDSIITVSYEEFLKSHKENK--VEEIPDSTMSICVPSETVDEIVKSGY-ISESE 309
Query: 310 QSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHP 369
S S+ ++ +T+ T L Q K +P+ K +
Sbjct: 310 NSEISQ----------QVRFKTV-----TVLAQVHPIPPKKTGKIPRIFLKQKQFEMENS 354
Query: 370 VETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQR-RKFMAK 428
+ S P ++ + + + E S A KP K T++++Q+ K +
Sbjct: 355 L--SDPENEQTVQKRKSNVVIQEEELELAVLEAGSSEAVKP---KCTLEERQQFMKAFRQ 409
Query: 429 PAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEE-HEEMGNDCVSKKQMPPVGSKKSS 487
PA + L G K + + ++ D N ++ E G VSK + + K S
Sbjct: 410 PASDALKNGVKKSSDKQKDLNEKCLYEVGRDDNSKKIMENSGIQMVSKNGNLQLHTDKGS 469
Query: 488 TRKDKEESKKKRFSSESKNKLVP---------EEVTSTVTKSRRISRRPSDWWVVKSEES 538
K+K + KK+ +P ++ T+ K ++ R S ++ ++
Sbjct: 470 FLKEKNKKLKKKNKKTLDTGAIPGKNREGNTQKKETTFFLKEKQYQNRMS----LRQRKT 525
Query: 539 PVYSNSSV-RNELPMHHNSSRKSTKKTN---QSSKNIRKKTIPLKRQKTATKGNQRVQKF 594
+ +S++ NE ++ + + K + ++K RK +IP+K K +
Sbjct: 526 EFFKSSTLFNNESLVYEDIANDDLLKVSSLCNNNKLSRKTSIPVKDIKLTQSKAESEASL 585
Query: 595 LNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKN 642
LN IS +E + ++D + N ST+ + N
Sbjct: 586 LNVSTPKSTRRSGRISSTPTTETIRGIDSD-DVQDNSQLKASTQKAAN 632
Score = 31.6 bits (70), Expect = 3.6
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 10/67 (14%)
Query: 464 EHEEMGNDCVSKKQMPPVGSKKSSTRK----DKEESKKKRFSSESKNKLVPEEVTSTVTK 519
EH+ + ++C SK+++ S K + RK + +SK+K+ + SKN + T K
Sbjct: 973 EHQVLSSECHSKQELEADVSHKETKRKLVEAENSKSKRKKPNEYSKN------LEKTNRK 1026
Query: 520 SRRISRR 526
S +S+R
Sbjct: 1027 SEELSKR 1033
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 42.7 bits (99), Expect = 0.002
Identities = 87/493 (17%), Positives = 179/493 (36%), Gaps = 57/493 (11%)
Query: 67 KDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNR-----SVQAHEVHQKIL 121
K I P E K + S +S+ + S ++ S+ E ++
Sbjct: 731 KTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKK 790
Query: 122 ATDVSSKNTPDSKKIS---SRNINDHHSEADEEFYLSVGSPSVL--LDAKTSVSQNVIPS 176
+ K D ++S S+ + D S+ +E +L L L + +Q + S
Sbjct: 791 TLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNS 850
Query: 177 SAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEID--NKVSDEEDKTSEG 234
Q++ F + S + + L K ++++E + N++ DE K +G
Sbjct: 851 KLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEA-KRIKG 909
Query: 235 QERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPD 294
++ K QN +++ + E+ + +K+ L E +KR+ E +HA
Sbjct: 910 EQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQ---------- 959
Query: 295 DTKLIEDEFIIDESDQSFASRSWI---------TIPRKAGSLKQRTISPAESTALLQGRK 345
E EF+ + + S I I R+ + KQ+ + E+ +
Sbjct: 960 -----EQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEER 1014
Query: 346 SREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSK 405
++ H +L + L + + ++ + + + + LI E N + +
Sbjct: 1015 HLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKI 1074
Query: 406 NAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQ--------SKDENI--HTSHITQ-DEF 454
+ K+ R A P +++ + Q K+E + H H Q +
Sbjct: 1075 QRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDL 1134
Query: 455 QRNSDRNMEEHEEMGN---------DCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESK 505
Q + N+ E ++ N + K++ S++ ++K +KK E
Sbjct: 1135 QLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFA 1194
Query: 506 NKLVPEEVTSTVT 518
KL +EV +T
Sbjct: 1195 RKLQEQEVFFKMT 1207
Score = 37.0 bits (84), Expect = 0.087
Identities = 107/561 (19%), Positives = 210/561 (37%), Gaps = 106/561 (18%)
Query: 63 TRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASL-----QFVVEPSEATNRSVQAH--E 115
+ +IKDT +Q+ Q++ K + + E L Q + + T + V ++ +
Sbjct: 488 SEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSD 547
Query: 116 VHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDA--------KT 167
V A DV+ K DS + + N E ++ + P V +A K
Sbjct: 548 VIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKL---INKPMVGPEAGGTKEVPIKE 604
Query: 168 SVSQNVIPSSAQKRETYTFENSV---NMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKV 224
V N I K + ++ N P +TE T+ +++E+ + V
Sbjct: 605 IVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSST-------EEMEVRSVV 657
Query: 225 SDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAA 284
+D + K G E + + +I + EI KK + V + +E P+
Sbjct: 658 ADTDQKAL-GSEVQDASKVTTQIDKEKKEIPVSIKKEPE---VTVVSQPTEPQPV----- 708
Query: 285 TAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSL-KQRTISPAESTALLQG 343
LI I +S ++ + GSL K TI P ES
Sbjct: 709 -------------LIPSININSDSGEN---------KEEIGSLSKTETILPPESEN---- 742
Query: 344 RKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMY 403
PK ND + + DTS + +++++ S +
Sbjct: 743 -----------PKENDNDSGTG-------------STADTSSIDLNLSISSFLSKTKDSG 778
Query: 404 SKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSD---- 459
S + ++ R K+T+K+ RKF+ E + V SK S + F R +
Sbjct: 779 SISLQETRRQKKTLKKT--RKFIVDGVE--VSVTTSKIVTDSDSKTEELRFLRRQELREL 834
Query: 460 RNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEE--SKKKRFSSESKNKLVPEEVTSTV 517
R +++ E+ ++ K ++ R+ ++E SKK+++ E +N ++ T
Sbjct: 835 RFLQKEEQRAQQQLNSKLQQ---QREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIER 891
Query: 518 TKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIP 577
+ +R + +K E+ S M N ++ + ++ K +RK+ +
Sbjct: 892 LEQEHTNRLRDEAKRIKGEQEKELSKFQ-----NMLKNRKKEVINEVEKAPKELRKELMK 946
Query: 578 LKRQKTATKGNQRVQKFLNAE 598
++++ A + + Q+F+ +
Sbjct: 947 RRKEELAQSQHAQEQEFVQKQ 967
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 42.4 bits (98), Expect = 0.002
Identities = 113/593 (19%), Positives = 207/593 (34%), Gaps = 75/593 (12%)
Query: 171 QNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDK 230
QN++ S + +++ E++ NM + ++ + K K+ L + + +IE S E++K
Sbjct: 200 QNLLHSEKRDKKSPLIESTANMDNNQSQKTFKNKETLIIEPEKNASRIE-----SLEQEK 254
Query: 231 TSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHS 290
E +E K SS + D E + + +A+ + + S+ A T P S
Sbjct: 255 VDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVS 314
Query: 291 C------------PPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAEST 338
P TK+ E E + + +W RK GS + AE T
Sbjct: 315 SGQATPTSPIKKFPTTATKISPKE----EERKDESPATWRLGLRKTGSYG----ALAEIT 366
Query: 339 ALLQGRKSREKHHNILPKTLANDKHSHKPHPVET--SQPSDKTVLDTSYALIGETVNNYR 396
A +G+K ++ T + + P + ++ +K T A + T+
Sbjct: 367 ASKEGQKEKD--------TAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRL 418
Query: 397 STKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHIT------ 450
++ ++ K + S S RT RRK+ E+ L S +E T H +
Sbjct: 419 ASTSDIEEKE-NRDSSSLRTSSSYTRRKW-----EDDLKKNSSVNEG-STYHKSCSFGRR 471
Query: 451 QDEFQRNSDRNMEEHEEMGNDCVSKKQM---------PPVGSKKSSTRKDKEESKKKRFS 501
QD+ +S + + + +K + GS + T+ S
Sbjct: 472 QDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDS 531
Query: 502 SESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNE-----LPMHHNS 556
+E + VP VT V + ++ S + + V S + VR P+
Sbjct: 532 TEKEKDSVPTAVTIPVAPT-VVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEE 590
Query: 557 SRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSE 616
S K ++ ++ R+ T Q Q +K + S E E
Sbjct: 591 SESQRKARSRQARQSRRST-----QGVTLTDLQEAEKTIGRSRSTR-TREQENEEKEKEE 644
Query: 617 PLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKP-QTSGYTCNIPTESNLDSGE 675
+ D+ +KK + SR + +P TS T + S + S
Sbjct: 645 KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL 704
Query: 676 HKTSVLEESG-----PSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIPKNR 723
+ +S L S + + + + E +D Q K I + R
Sbjct: 705 YASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERR 757
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 42.4 bits (98), Expect = 0.002
Identities = 113/593 (19%), Positives = 207/593 (34%), Gaps = 75/593 (12%)
Query: 171 QNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDK 230
QN++ S + +++ E++ NM + ++ + K K+ L + + +IE S E++K
Sbjct: 287 QNLLHSEKRDKKSPLIESTANMDNNQSQKTFKNKETLIIEPEKNASRIE-----SLEQEK 341
Query: 231 TSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHS 290
E +E K SS + D E + + +A+ + + S+ A T P S
Sbjct: 342 VDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVS 401
Query: 291 C------------PPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAEST 338
P TK+ E E + + +W RK GS + AE T
Sbjct: 402 SGQATPTSPIKKFPTTATKISPKE----EERKDESPATWRLGLRKTGSYG----ALAEIT 453
Query: 339 ALLQGRKSREKHHNILPKTLANDKHSHKPHPVET--SQPSDKTVLDTSYALIGETVNNYR 396
A +G+K ++ T + + P + ++ +K T A + T+
Sbjct: 454 ASKEGQKEKD--------TAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRL 505
Query: 397 STKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHIT------ 450
++ ++ K + S S RT RRK+ E+ L S +E T H +
Sbjct: 506 ASTSDIEEKE-NRDSSSLRTSSSYTRRKW-----EDDLKKNSSVNEG-STYHKSCSFGRR 558
Query: 451 QDEFQRNSDRNMEEHEEMGNDCVSKKQM---------PPVGSKKSSTRKDKEESKKKRFS 501
QD+ +S + + + +K + GS + T+ S
Sbjct: 559 QDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDS 618
Query: 502 SESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNE-----LPMHHNS 556
+E + VP VT V + ++ S + + V S + VR P+
Sbjct: 619 TEKEKDSVPTAVTIPVAPT-VVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEE 677
Query: 557 SRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSE 616
S K ++ ++ R+ T Q Q +K + S E E
Sbjct: 678 SESQRKARSRQARQSRRST-----QGVTLTDLQEAEKTIGRSRSTR-TREQENEEKEKEE 731
Query: 617 PLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKP-QTSGYTCNIPTESNLDSGE 675
+ D+ +KK + SR + +P TS T + S + S
Sbjct: 732 KEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL 791
Query: 676 HKTSVLEESG-----PSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIPKNR 723
+ +S L S + + + + E +D Q K I + R
Sbjct: 792 YASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERR 844
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,456,562
Number of Sequences: 37866
Number of extensions: 1708938
Number of successful extensions: 7412
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 419
Number of HSP's that attempted gapping in prelim test: 6380
Number of HSP's gapped (non-prelim): 1228
length of query: 943
length of database: 18,247,518
effective HSP length: 112
effective length of query: 831
effective length of database: 14,006,526
effective search space: 11639423106
effective search space used: 11639423106
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.