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Search of human proteins with 66932949
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66932949 ATPase type 13A4 [Homo sapiens]
(1196 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66932949 ATPase type 13A4 [Homo sapiens] 2403 0.0
gi|66730421 ATPase type 13A5 [Homo sapiens] 1407 0.0
gi|148839292 ATPase type 13A3 [Homo sapiens] 993 0.0
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 766 0.0
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 765 0.0
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] 713 0.0
gi|170016077 ATPase type 13A1 [Homo sapiens] 275 1e-73
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 142 2e-33
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 142 2e-33
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 142 2e-33
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 142 2e-33
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 124 7e-28
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 124 7e-28
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 120 8e-27
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 119 2e-26
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 119 2e-26
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 119 2e-26
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 119 2e-26
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 117 5e-26
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 116 1e-25
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 112 2e-24
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 112 2e-24
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 111 4e-24
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 111 5e-24
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 106 1e-22
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 106 1e-22
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 106 1e-22
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 106 1e-22
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 106 1e-22
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 106 1e-22
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 2403 bits (6228), Expect = 0.0
Identities = 1196/1196 (100%), Positives = 1196/1196 (100%)
Query: 1 MGHFEKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWA 60
MGHFEKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWA
Sbjct: 1 MGHFEKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWA 60
Query: 61 HCVPCSLQEADTVLLRTTDEFQIYSWKKVIWIYLSALNSAFGLTPDHPLMTDEEYIINRA 120
HCVPCSLQEADTVLLRTTDEFQIYSWKKVIWIYLSALNSAFGLTPDHPLMTDEEYIINRA
Sbjct: 61 HCVPCSLQEADTVLLRTTDEFQIYSWKKVIWIYLSALNSAFGLTPDHPLMTDEEYIINRA 120
Query: 121 IRKPDLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRL 180
IRKPDLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRL
Sbjct: 121 IRKPDLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRL 180
Query: 181 ICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLT 240
ICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLT
Sbjct: 181 ICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLT 240
Query: 241 VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAV 300
VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAV
Sbjct: 241 VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAV 300
Query: 301 LIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAAC 360
LIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAAC
Sbjct: 301 LIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAAC 360
Query: 361 SGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVY 420
SGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVY
Sbjct: 361 SGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVY 420
Query: 421 VLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQL 480
VLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQL
Sbjct: 421 VLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQL 480
Query: 481 NLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLD 540
NLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLD
Sbjct: 481 NLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLD 540
Query: 541 GTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFP 600
GTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFP
Sbjct: 541 GTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFP 600
Query: 601 FSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIAL 660
FSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIAL
Sbjct: 601 FSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIAL 660
Query: 661 AYKKLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDN 720
AYKKLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDN
Sbjct: 661 AYKKLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDN 720
Query: 721 LQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRD 780
LQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRD
Sbjct: 721 LQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRD 780
Query: 781 EVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLD 840
EVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLD
Sbjct: 781 EVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLD 840
Query: 841 YFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTS 900
YFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTS
Sbjct: 841 YFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTS 900
Query: 901 FCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPF 960
FCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPF
Sbjct: 901 FCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPF 960
Query: 961 RPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMS 1020
RPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMS
Sbjct: 961 RPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMS 1020
Query: 1021 PTAPEKMESNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQL 1080
PTAPEKMESNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQL
Sbjct: 1021 PTAPEKMESNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQL 1080
Query: 1081 GVCLFILFADIPELYRRLDLLCTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIK 1140
GVCLFILFADIPELYRRLDLLCTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIK
Sbjct: 1081 GVCLFILFADIPELYRRLDLLCTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIK 1140
Query: 1141 RCFGYQSKSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEEQL 1196
RCFGYQSKSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEEQL
Sbjct: 1141 RCFGYQSKSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEEQL 1196
>gi|66730421 ATPase type 13A5 [Homo sapiens]
Length = 1218
Score = 1407 bits (3642), Expect = 0.0
Identities = 709/1200 (59%), Positives = 900/1200 (75%), Gaps = 18/1200 (1%)
Query: 5 EKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWAHCVP 64
+K ALLN+GEE+E+E+FGYR RK+ CL S+ + G L LVFYWRP W VWA+C+P
Sbjct: 6 KKDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIP 65
Query: 65 CSLQEADTVLLRTTDEFQIYSWKKVIWIYLSALNSAFGLTPDHPLMTDEEYIINRAIRKP 124
C LQEADTVLLRTTDEFQ Y KKV +YLS L + L+ D +IN+A+ KP
Sbjct: 66 CPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWEESLVADRHSVINQALIKP 125
Query: 125 DLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGP 184
+LK+RC++VQKIRYVWN LE +FQK+G LED S + IHQ FG GLT EEQE+RRL+CGP
Sbjct: 126 ELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGP 185
Query: 185 NTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDL 244
N I+VE+ PIWKLL+K+VLNPFY+FQ F++ LW S+ Y EY+ AIII+++ISI L+VYDL
Sbjct: 186 NAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDL 245
Query: 245 REQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEG 304
R+QSVKLH+LVE HN + V++ + G++ELESR+LVPGD+LIL G K +PCDAVLI+G
Sbjct: 246 RQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPG-KFSLPCDAVLIDG 304
Query: 305 SCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTV 364
SCVV+EGMLTGESIPVTKTPLP+M++++PWK S DY++HVLFCGTEVIQ K + G V
Sbjct: 305 SCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPV 364
Query: 365 RAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSG 424
RAVVLQTG+NTAKGDLVRSILYP+P+NF+LY DA +F++ L +G Y L VY+ G
Sbjct: 365 RAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHG 424
Query: 425 EPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVC 484
PP++ V AL ++T+ VPP LPAALT G +YAQ+RLKK+ IFCISPQRIN+CGQ+NLVC
Sbjct: 425 VPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVC 484
Query: 485 FDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQ 544
FDKTGTLT DGLDLWG V N FQE HSFASGQA+PW PLCAAMASCHSLILL+GTIQ
Sbjct: 485 FDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQ 544
Query: 545 GDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSA 604
GDPLDLKMFE T W+M D K + + ++KP AS+ PVE I L QFPFSS+
Sbjct: 545 GDPLDLKMFEGTAWKMEDCIVD-SCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPFSSS 603
Query: 605 LQRMTVIVQEMGGDRL-AFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYK 663
LQRM+VI Q G + +MKGAPE VA FC+ ETVP +F EL+ YT QGFRVIALA+K
Sbjct: 604 LQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHK 663
Query: 664 --KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNL 721
K+ N L RE VES+L FLGLLI+ENRLK+ETK VL+EL ARIRTVMITGDNL
Sbjct: 664 TLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNL 723
Query: 722 QTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDE 781
QTAITVA+ S M+ +VI++EA+E AS++W LVE ++ G ++ Y++ +
Sbjct: 724 QTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQE-TGPGKKEIYMHTGNS 782
Query: 782 VSDKGREGS-YHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLD 840
+ +G GS YHFA++GKS+ VI QHF+SLLPKIL+NGT+FARMSPGQKSSL+EEFQKL+
Sbjct: 783 STPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLN 842
Query: 841 YFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTS 900
Y+VGMCGDGANDCGALK AH GISLSEQEASVASPFTSKT NI+CVPHLI+EGRAALV+S
Sbjct: 843 YYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSS 902
Query: 901 FCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPF 960
F +FKY+ +Y +IQ++ LLLYW+ NYQ+L QD+AIT ++ +TM+ AYPKL P+
Sbjct: 903 FGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPY 962
Query: 961 RPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWY-SVEIHSACTVQNESISELTM 1019
RPAG+L+SPPLLLS+ N S + I+ F+ V++QPWY V +S C + N+ S +
Sbjct: 963 RPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQ--SNFST 1020
Query: 1020 SPTAPEKMESNST-----FTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVL 1074
+ + N+T SFE TT+W + TIN ITVA +FSKGKPFR+P YTNYIF
Sbjct: 1021 NVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSF 1080
Query: 1075 VLIIQLGVCLFILFADIPELYRRLDLLCTPVLWRASIVIMLSLNFIVSLVAEEAVIENRA 1134
+L+ LG+ +FILF+D +YR ++L+ T WR I+++ F V+ E+++++N
Sbjct: 1081 LLLAALGLTIFILFSDFQVIYRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHE 1140
Query: 1135 LWMMIKRCFGYQSKSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEE 1194
LW++IKR FG+ SKSQYR WQ+ LA D +WPP+N+T +S G+ Y N +ES+E+
Sbjct: 1141 LWLLIKREFGFYSKSQYRTWQKKLAEDSTWPPINRTDYSG---DGKNGFYINGGYESHEQ 1197
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 993 bits (2566), Expect = 0.0
Identities = 542/1211 (44%), Positives = 762/1211 (62%), Gaps = 49/1211 (4%)
Query: 5 EKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWAHCVP 64
++ + +N+G+E+EMEI+GY + ++ G I S G L L+ YW P W V A CV
Sbjct: 2 DREERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVR 61
Query: 65 CSLQEADTVLLRTTDEFQIYSWKKVIWIYL------SALNSAFGLTPDHPLMTDEE---- 114
++++ + VLLRTTDEF+++ K+ + L S + + L+ H + E
Sbjct: 62 AAIKDCEVVLLRTTDEFKMWFCAKIRVLSLETYPVSSPKSMSNKLSNGHAVCLIENPTEE 121
Query: 115 --YIINRAIRKPDLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTR 172
+ I++ + ++R ++Y WN F + L++ +S I++K +GLT+
Sbjct: 122 NRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTK 181
Query: 173 EEQEIRRLICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIM 232
R+L+ G N I V+V ++KLLIKEVLNPFYIFQLFSV LW +++Y YA AI++M
Sbjct: 182 GMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVM 241
Query: 233 SIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNK 292
SI+SI ++Y +R+Q V LH +V +H+++ VSVC ++E+ S LVPGD++++ N
Sbjct: 242 SIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNG 301
Query: 293 VLMPCDAVLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPW---KTQSEADYKRHVLFC 349
+MPCDAVLI G+C+V+E MLTGES+PVTKT LP V + + +KRH LFC
Sbjct: 302 TIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFC 361
Query: 350 GTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTA 409
GT VIQ + V+A+V++TGF+T+KG LVRSILYPKP +F+LYRDA FLLCLV A
Sbjct: 362 GTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVA 421
Query: 410 TIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCI 469
IG IYT+ +L+ ++ ++LD+ITI VPPALPAA+T GI+YAQRRLKK GIFCI
Sbjct: 422 GIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCI 481
Query: 470 SPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAA 529
SPQRIN+CGQLNLVCFDKTGTLT DGLDLWG+ + F + L A
Sbjct: 482 SPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVAC 541
Query: 530 MASCHSLILLDGTIQGDPLDLKMFEATTWEMAFSGDD---FHIKGVPAHAMVVKPCRT-- 584
MA+CHSL ++G + GDPLDLKMFEA W + + ++ H + +P VV+P +
Sbjct: 542 MATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPT---VVRPPKQLL 598
Query: 585 -----ASQVPVE--------GIAILHQFPFSSALQRMTVIVQEMGGDRL-AFMKGAPERV 630
A +E I I+ QFPFSSALQRM+V+ + +G ++ A+MKGAPE +
Sbjct: 599 PESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAI 658
Query: 631 ASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLEND---HHATTLTRETVESDLIFLG 687
A C+PETVP F + L+ +T QGFRVIALA++KLE+ H ++R+ +E+++ F+G
Sbjct: 659 AGLCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMG 718
Query: 688 LLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANE 747
L+I++N+LK+ET VLE+L A IRTVM+TGD++ TA++VAR GM+ KVI+ EA
Sbjct: 719 LIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALP 778
Query: 748 TTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREG----SYHFALTGKSFHVI 803
A I+W + + + + I ++ E YHFA+ GKSF VI
Sbjct: 779 PKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVI 838
Query: 804 SQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGI 863
+HF L+PK++++GT+FARM+P QK+ L+E Q +DYFVGMCGDGANDCGALK AH GI
Sbjct: 839 LEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGI 898
Query: 864 SLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYW 923
SLSE EASVASPFTSKTP+I CVP+LI+EGRAAL+TSFC+FK+MALYS+IQY V LLY
Sbjct: 899 SLSELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYS 958
Query: 924 ETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSL 983
++L ++QFLF DLAI ++ TM+LN A+ +LV RP LIS LL SV+ I++ +
Sbjct: 959 ILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICI 1018
Query: 984 AMHIAGFILVQRQPWYSV--EIHSACTVQNESISELTMSPTAPEKMESNSTFTSFENTTV 1041
GF V++QPWY V AC + E E N ++ENTTV
Sbjct: 1019 GFQSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHN--IQNYENTTV 1076
Query: 1042 WFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFADIPELYRRLDLL 1101
+F+ + + VA+ FSKGKPFRQP Y NY FV +I LFI+ + + + L ++
Sbjct: 1077 FFISSFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIV 1136
Query: 1102 CTPVLWRASIVIMLSLNFIVSLVAEEAVIE-NRALWMMIKRCFGYQSKSQYRIWQRDLAN 1160
C P WR +++I++ +N VS+ EE+V + C K++Y ++L
Sbjct: 1137 CVPYQWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRKKTPKAKYMYLAQELLV 1196
Query: 1161 DPSWPPLNQTS 1171
DP WPP QT+
Sbjct: 1197 DPEWPPKPQTT 1207
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 766 bits (1977), Expect = 0.0
Identities = 471/1164 (40%), Positives = 677/1164 (58%), Gaps = 88/1164 (7%)
Query: 44 GILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKK-VIWIYLSALN---- 98
GI L+F W+P W V PC+L A+T+++ D+ + SW+ + + A+
Sbjct: 59 GIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDK-EDSSWQLFTVQVQTEAIGEGSL 117
Query: 99 --------------SAFGLTPDHPLM-TDEEYIINRAIRKPDLKV-RCIKVQKIRYVWNY 142
+A G P+ T + + A+ +V R Q RY+W
Sbjct: 118 EPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIE 177
Query: 143 LEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEV 202
+ F ++ L+ S +H+ GL+ ++Q +R+ I GPN I + V +LL+ E
Sbjct: 178 TQQAFYQVSLLDHGRSCDDVHRS-RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEA 236
Query: 203 LNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSIT 262
LNP+Y FQ FS+ LW ++ Y YA I ++S ISI L++Y R+QS L +V+ S+
Sbjct: 237 LNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKL--SMR 294
Query: 263 VSVCGRKAGVQE-LESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVT 321
V VC R G +E ++S LVPGD L+L LMPCDA L+ G C+V+E LTGESIPV
Sbjct: 295 VCVC-RPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVL 353
Query: 322 KTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLV 381
KT LP + P+ ++ ++RH LFCGT ++QA+A V AVV +TGF TAKG LV
Sbjct: 354 KTALP--EGLGPYCAET---HRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLV 408
Query: 382 RSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIA 441
SIL+P+P+NF+ Y+ +++F+ L A +G IY++ + + P E+V +ALD++T+
Sbjct: 409 SSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVV 468
Query: 442 VPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGV 501
VPPALPAA+T +YAQ RL+++GIFCI P RIN+ G+L LVCFDKTGTLT DGLD+ GV
Sbjct: 469 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGV 528
Query: 502 VSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW--- 558
V F + + LP GPL A+A+CH+L L T GDP+DLKM E+T W
Sbjct: 529 VPLKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLE 586
Query: 559 -----EMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQ 613
+ AF + P + +P A + P +++LH+FPFSSALQRM+V+V
Sbjct: 587 EEPAADSAFGTQVLAVMRPP----LWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVA 642
Query: 614 EMGGDRL-AFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLEND---H 669
G + A++KG+PE VA C PETVPT F LQ YT G+RV+ALA K L
Sbjct: 643 WPGATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLE 702
Query: 670 HATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVAR 729
A LTR+TVE DL LGLL++ N LK +T PV++ L RIR VM+TGDNLQTA+TVAR
Sbjct: 703 AAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVAR 762
Query: 730 KSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREG 789
GMV+ + +I++ A AS+ + +E + N + D+ + E
Sbjct: 763 GCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAV------NGVKDPDQAASYTVEP 816
Query: 790 ---SYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMC 846
S H AL+G +F +I +HF LLPK+L+ GT+FARM+P QK+ LV E QKL Y VGMC
Sbjct: 817 DPRSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMC 876
Query: 847 GDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKY 906
GDGANDCGALK A VGISLS+ EASV SPFTS +IECVP +I+EGR +L TSF +FKY
Sbjct: 877 GDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKY 936
Query: 907 MALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRL 966
MALYS+ Q++ VL+LY +L + QFL DL ITT + V M+ G L RP G L
Sbjct: 937 MALYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGAL 996
Query: 967 ISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEK 1026
+S P+L S++ ++L + + G+ L QPW+ L + AP+
Sbjct: 997 LSVPVLSSLLLQMVLVTGVQLGGYFLTLAQPWF---------------VPLNRTVAAPDN 1041
Query: 1027 MESNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFI 1086
+ ++ENT V+ L + + +A SKG PFR+P YTN F++ L + V + +
Sbjct: 1042 L------PNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVALALLSSVLVGL 1095
Query: 1087 LFADIPELYRRLDLL--CTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIKRCFG 1144
+ +P L + L T ++ ++ +++LNF+ + + E + ++ L ++R
Sbjct: 1096 VL--VPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVL--DQCLPACLRRLRP 1151
Query: 1145 YQ-SKSQYRIWQRDLANDPSWPPL 1167
+ SK +++ +R+LA P WPPL
Sbjct: 1152 KRASKKRFKQLERELAEQP-WPPL 1174
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 765 bits (1976), Expect = 0.0
Identities = 468/1162 (40%), Positives = 675/1162 (58%), Gaps = 89/1162 (7%)
Query: 44 GILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKK-VIWIYLSALN---- 98
GI L+F W+P W V PC+L A+T+++ D+ + SW+ + + A+
Sbjct: 59 GIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDK-EDSSWQLFTVQVQTEAIGEGSL 117
Query: 99 --------------SAFGLTPDHPLMTDEEYIINRAIRKPDLKVRCIKVQKIRYVWNYLE 144
+A G P+ + + ++ +R Q RY+W +
Sbjct: 118 EPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRV---LRYYLFQGQRYIWIETQ 174
Query: 145 GQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLN 204
F ++ L+ S +H+ GL+ ++Q +R+ I GPN I + V +LL+ E LN
Sbjct: 175 QAFYQVSLLDHGRSCDDVHRS-RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
Query: 205 PFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVS 264
P+Y FQ FS+ LW ++ Y YA I ++S ISI L++Y R+QS L +V+ S+ V
Sbjct: 234 PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKL--SMRVC 291
Query: 265 VCGRKAGVQE-LESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKT 323
VC R G +E ++S LVPGD L+L LMPCDA L+ G C+V+E LTGESIPV KT
Sbjct: 292 VC-RPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKT 350
Query: 324 PLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRS 383
LP + P+ ++ ++RH LFCGT ++QA+A V AVV +TGF TAKG LV S
Sbjct: 351 ALP--EGLGPYCAET---HRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSS 405
Query: 384 ILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVP 443
IL+P+P+NF+ Y+ +++F+ L A +G IY++ + + P E+V +ALD++T+ VP
Sbjct: 406 ILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVP 465
Query: 444 PALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVS 503
PALPAA+T +YAQ RL+++GIFCI P RIN+ G+L LVCFDKTGTLT DGLD+ GVV
Sbjct: 466 PALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVP 525
Query: 504 CDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW----- 558
F + + LP GPL A+A+CH+L L T GDP+DLKM E+T W
Sbjct: 526 LKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEE 583
Query: 559 ---EMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEM 615
+ AF + P + +P A + P +++LH+FPFSSALQRM+V+V
Sbjct: 584 PAADSAFGTQVLAVMRPP----LWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWP 639
Query: 616 GGDRL-AFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLEND---HHA 671
G + A++KG+PE VA C PETVPT F LQ YT G+RV+ALA K L A
Sbjct: 640 GATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAA 699
Query: 672 TTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKS 731
LTR+TVE DL LGLL++ N LK +T PV++ L RIR VM+TGDNLQTA+TVAR
Sbjct: 700 QQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGC 759
Query: 732 GMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREG-- 789
GMV+ + +I++ A AS+ + +E + N + D+ + E
Sbjct: 760 GMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAV------NGVKDPDQAASYTVEPDP 813
Query: 790 -SYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGD 848
S H AL+G +F +I +HF LLPK+L+ GT+FARM+P QK+ LV E QKL Y VGMCGD
Sbjct: 814 RSRHLALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGD 873
Query: 849 GANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMA 908
GANDCGALK A VGISLS+ EASV SPFTS +IECVP +I+EGR +L TSF +FKYMA
Sbjct: 874 GANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMA 933
Query: 909 LYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLIS 968
LYS+ Q++ VL+LY +L + QFL DL ITT + V M+ G L RP G L+S
Sbjct: 934 LYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLS 993
Query: 969 PPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKME 1028
P+L S++ ++L + + G+ L QPW+ L + AP+ +
Sbjct: 994 VPVLSSLLLQMVLVTGVQLGGYFLTLAQPWF---------------VPLNRTVAAPDNL- 1037
Query: 1029 SNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILF 1088
++ENT V+ L + + +A SKG PFR+P YTN F++ L + V + ++
Sbjct: 1038 -----PNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPFLVALALLSSVLVGLVL 1092
Query: 1089 ADIPELYRRLDLL--CTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIKRCFGYQ 1146
+P L + L T ++ ++ +++LNF+ + + E + ++ L ++R +
Sbjct: 1093 --VPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLESVL--DQCLPACLRRLRPKR 1148
Query: 1147 -SKSQYRIWQRDLANDPSWPPL 1167
SK +++ +R+LA P WPPL
Sbjct: 1149 ASKKRFKQLERELAEQP-WPPL 1169
>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
Length = 1158
Score = 713 bits (1840), Expect = 0.0
Identities = 432/1058 (40%), Positives = 604/1058 (57%), Gaps = 114/1058 (10%)
Query: 44 GILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKK-VIWIYLSALN---- 98
GI L+F W+P W V PC+L A+T+++ D+ + SW+ + + A+
Sbjct: 59 GIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDK-EDSSWQLFTVQVQTEAIGEGSL 117
Query: 99 --------------SAFGLTPDHPLMTDEEYIINRAIRKPDLKVRCIKVQKIRYVWNYLE 144
+A G P+ + + ++ +R Q RY+W +
Sbjct: 118 EPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRV---LRYYLFQGQRYIWIETQ 174
Query: 145 GQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLN 204
F ++ L+ S +H+ GL+ ++Q +R+ I GPN I + V +LL+ E LN
Sbjct: 175 QAFYQVSLLDHGRSCDDVHRS-RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
Query: 205 PFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVS 264
P+Y FQ FS+ LW ++ Y YA I ++S ISI L++Y R+QS L +V+ S+ V
Sbjct: 234 PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKL--SMRVC 291
Query: 265 VCGRKAGVQE-LESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKT 323
VC R G +E ++S LVPGD L+L LMPCDA L+ G C+V+E LTGESIPV KT
Sbjct: 292 VC-RPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKT 350
Query: 324 PLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRS 383
LP + P+ ++ ++RH LFCGT ++QA+A V AVV +TGF TAKG LV S
Sbjct: 351 ALP--EGLGPYCAET---HRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSS 405
Query: 384 ILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVP 443
IL+P+P+NF+ Y+ +++F+ L A +G IY++ + + P E+V +ALD++T+ VP
Sbjct: 406 ILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVP 465
Query: 444 PALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVS 503
PALPAA+T +YAQ RL+++GIFCI P RIN+ G+L LVCFDKTGTLT DGLD+ GVV
Sbjct: 466 PALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVP 525
Query: 504 CDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW----- 558
F + + LP GPL A+A+CH+L L T GDP+DLKM E+T W
Sbjct: 526 LKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEE 583
Query: 559 ---EMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEM 615
+ AF + P + +P A + P +++LH+FPFSSALQRM+V+V
Sbjct: 584 PAADSAFGTQVLAVMRPP----LWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWP 639
Query: 616 GGDR-LAFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKL---ENDHHA 671
G + A++KG+PE VA C PETVPT F LQ YT G+RV+ALA K L + A
Sbjct: 640 GATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAA 699
Query: 672 TTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKS 731
LTR+TVE DL LGLL++ N LK +T PV++ L RIR VM+TGDNLQTA+TVAR
Sbjct: 700 QQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGC 759
Query: 732 GMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSY 791
GMV+ + +I++ A AS+ + +E
Sbjct: 760 GMVAPQEHLIIVHATHPERGQPASLEFLPMESPT-------------------------- 793
Query: 792 HFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGAN 851
A+ G K+L+ GT+FARM+P QK+ LV E QKL Y VGMCGDGAN
Sbjct: 794 --AVNG--------------VKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGAN 837
Query: 852 DCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYS 911
DCGALK A VGISLS+ EASV SPFTS +IECVP +I+EGR +L TSF +FKYMALYS
Sbjct: 838 DCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
Query: 912 MIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPL 971
+ Q++ VL+LY +L + QFL DL ITT + V M+ G L RP G L+S P+
Sbjct: 898 LTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPV 957
Query: 972 LLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKMESNS 1031
L S++ ++L + + G+ L QPW+ L + AP+ +
Sbjct: 958 LSSLLLQMVLVTGVQLGGYFLTLAQPWF---------------VPLNRTVAAPDNL---- 998
Query: 1032 TFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTN 1069
++ENT V+ L + + +A SKG PFR+P YTN
Sbjct: 999 --PNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034
>gi|170016077 ATPase type 13A1 [Homo sapiens]
Length = 1204
Score = 275 bits (704), Expect = 1e-73
Identities = 232/768 (30%), Positives = 371/768 (48%), Gaps = 81/768 (10%)
Query: 126 LKVRCIKVQKIRYVWNYLEG-QFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLI--C 182
L+V + QKI+Y ++ LE QF + + +A + + G +E+ EIR
Sbjct: 167 LEVLSFEFQKIKYSYDALEKKQFLPVAFP---VGNAFSYYQSNRGF-QEDSEIRAAEKKF 222
Query: 183 GPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYA-FAIIIMSIISISLTV 241
G N ++ V +L + PF++FQ+F V LW ++Y Y+ F + ++ SL
Sbjct: 223 GSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQ 282
Query: 242 YDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLIL--TGNKVLMPCDA 299
+R S ++ + + I V R + + S +VPGD++ + + + L+PCD
Sbjct: 283 QQMRNMS-EIRKMGNKPHMIQVY---RSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDV 338
Query: 300 VLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQ---- 355
+L+ G C+VDE MLTGES+P K P+ D S +AD + HV+F GT+V+Q
Sbjct: 339 LLLRGRCIVDEAMLTGESVPQMKEPIE--DLSPDRVLDLQADSRLHVIFGGTKVVQHIPP 396
Query: 356 ------AKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTA 409
K SG V A VL+TGFNT++G L+R+IL+ + F+L L+ A
Sbjct: 397 QKATTGLKPVDSGCV-AYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLLVFA 455
Query: 410 TIGMIYTLCVYVLSGEPPE----EVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRG 465
Y V++ + P ++ + ++T VPP LP L+ + + L K
Sbjct: 456 IAAAAY---VWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLY 512
Query: 466 IFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGP 525
++C P RI G++ + CFDKTGTLT D L + GV G ++ ++P
Sbjct: 513 MYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVA-----GLRDGKEVTPVSSIPV-E 566
Query: 526 LCAAMASCHSLILLD-GTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRT 584
A+ASCHSL+ LD GT+ GDPL+ M A W + F
Sbjct: 567 THRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVF----------------- 609
Query: 585 ASQVPVEGIAILHQFPFSSALQRMTVIV--QEMGGDRLAFM---KGAPERVASFCQPETV 639
+ +G+ I +F F+SAL+RM+V+ +++G L ++ KGAPE + S
Sbjct: 610 PRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQ--C 667
Query: 640 PTSFVSELQIYTTQGFRVIALAYKKLENDHH--ATTLTRETVESDLIFLGLLILENRLKE 697
P + + +G RV+AL YK+L + H A + RE +E L F+G +++ LK
Sbjct: 668 PPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPLKA 727
Query: 698 ETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASIS 757
++K V+ E+ +A R VMITGDN TA VA++ + ++ +IL +E
Sbjct: 728 DSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSE----KGRQCE 783
Query: 758 WTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILIN 817
W ++ + S K Y LTG + L +++ +
Sbjct: 784 WRSIDGSIVLPLARG----------SPKALALEYALCLTGDGLAHLQATDPQQLLRLIPH 833
Query: 818 GTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISL 865
+FAR++P QK ++ ++L Y MCGDG ND GALK A VG++L
Sbjct: 834 VQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
Score = 83.6 bits (205), Expect = 1e-15
Identities = 70/268 (26%), Positives = 120/268 (44%), Gaps = 36/268 (13%)
Query: 869 EASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWETNSL 928
+AS+A+PFTSK +I+C+ H+IK+GR LVT+ MFK +AL ++I +LY E
Sbjct: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
Query: 929 SNYQFLFQDLAITTLIGVTMNLNGAYP--KLVPFRPAGRLISPPLLLSVIFNILLSLAMH 986
S++Q Q L L G + ++ + P L RP + + L I ++L +H
Sbjct: 1013 SDFQATLQGL---LLAGCFLFISRSKPLKTLSRERPLPNIFN----LYTILTVMLQFFVH 1065
Query: 987 IAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKMES-NSTFTSFE----NTTV 1041
+ + R+ +PEK E + FE N+TV
Sbjct: 1066 FLSLVYLYRE----------------------AQARSPEKQEQFVDLYKEFEPSLVNSTV 1103
Query: 1042 WFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFADIPELYRRLDLL 1101
+ + + + KG PF + N V L + L + +L P+ + L+
Sbjct: 1104 YIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLV 1163
Query: 1102 CTPVLWRASIVIMLSLNFIVSLVAEEAV 1129
PV ++ I +L L+F ++L+A+ +
Sbjct: 1164 DIPVEFKLVIAQVLLLDFCLALLADRVL 1191
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
sapiens]
Length = 939
Score = 142 bits (358), Expect = 2e-33
Identities = 209/870 (24%), Positives = 352/870 (40%), Gaps = 164/870 (18%)
Query: 168 SGLTREEQEIRRLICGPNTIDV-EVTPIWKLLIKEVLNPFYIFQL----FSVCLWFSEDY 222
+GL + E RR G N D+ E P+WK I + NP + L SV + +D
Sbjct: 44 NGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA 103
Query: 223 KEYAFAIIIMSIISISLTVYDLREQSVKLHHLV--ESHNSITVSVCGRKAGVQELESRVL 280
AI+I+ ++ + Y + +L LV E H C R+ ++ +R L
Sbjct: 104 VSITVAILIVVTVAF-VQEYRSEKSLEELSKLVPPECH-------CVREGKLEHTLARDL 155
Query: 281 VPGDLLILT-GNKVLMPCDAVLIEG-SCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQS 338
VPGD + L+ G++V P D L E +DE LTGE+ P +K P+ P T
Sbjct: 156 VPGDTVCLSVGDRV--PADLRLFEAVDLSIDESSLTGETTPCSKVTAPQ-----PAATNG 208
Query: 339 EADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYR-- 396
+ + ++ F GT V KA + VV+ TG N+ G++ + + + L +
Sbjct: 209 DLASRSNIAFMGTLVRCGKA------KGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSM 262
Query: 397 DAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGI-I 455
D + L IG+I + V L G+ E+ ++ + A+P LP +T + +
Sbjct: 263 DLLGKQLSFYSFGIIGII--MLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLAL 320
Query: 456 YAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCD---------- 505
R +KKR I P + G N++C DKTGTLT++ + + + + D
Sbjct: 321 GVMRMVKKRAIVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVG 379
Query: 506 RNGFQE-------VHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW 558
N F E VH F + + A C+ ++ + T+ G P + + A
Sbjct: 380 YNQFGEVIVDGDVVHGFYNPAV---SRIVEAGCVCNDAVIRNNTLMGKPTEGALI-ALAM 435
Query: 559 EMAFSG--DDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTV-IVQEM 615
+M G D+ K ++PFSS + M V V
Sbjct: 436 KMGLDGLQQDYIRKA--------------------------EYPFSSEQKWMAVKCVHRT 469
Query: 616 GGDR--LAFMKGAPERVASFCQPETVPTSFVSELQIYT-TQGFRVIALAYKKLENDH--H 670
DR + FMKGA E+V +C T++ S+ Q T TQ R + K
Sbjct: 470 QQDRPEICFMKGAYEQVIKYC------TTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLR 523
Query: 671 ATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARK 730
L L FLGL+ + + + K + LI++ + MITGD+ +TA+ +A +
Sbjct: 524 VLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583
Query: 731 SGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGS 790
G+ S+ +S S+S G + + ++++
Sbjct: 584 LGLYSK---------------TSQSVS------------GEEIDAMDVQ----------- 605
Query: 791 YHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGA 850
S ++PK+ +F R SP K +++ QK V M GDG
Sbjct: 606 ---------------QLSQIVPKV----AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGV 646
Query: 851 NDCGALKMAHVGISLSEQEASV---ASPFTSKTPNIECVPHLIKEGRAAL--VTSFCMFK 905
ND ALK A +G+++ + V A+ + + + I+EG+ + +F F+
Sbjct: 647 NDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQ 706
Query: 906 YMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYP--KLVPFRPA 963
+ + + + L N L+ Q L+ ++ + G G P K V +P
Sbjct: 707 LSTSIAALTLISLATLMNFPNPLNAMQILWINIIMD---GPPAQSLGVEPVDKDVIRKPP 763
Query: 964 GRLISPPLLLSVIFNILLSLAMHIAGFILV 993
L ++I IL+S + + G + V
Sbjct: 764 RNWKDSILTKNLILKILVSSIIIVCGTLFV 793
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
sapiens]
Length = 949
Score = 142 bits (358), Expect = 2e-33
Identities = 209/870 (24%), Positives = 352/870 (40%), Gaps = 164/870 (18%)
Query: 168 SGLTREEQEIRRLICGPNTIDV-EVTPIWKLLIKEVLNPFYIFQL----FSVCLWFSEDY 222
+GL + E RR G N D+ E P+WK I + NP + L SV + +D
Sbjct: 44 NGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA 103
Query: 223 KEYAFAIIIMSIISISLTVYDLREQSVKLHHLV--ESHNSITVSVCGRKAGVQELESRVL 280
AI+I+ ++ + Y + +L LV E H C R+ ++ +R L
Sbjct: 104 VSITVAILIVVTVAF-VQEYRSEKSLEELSKLVPPECH-------CVREGKLEHTLARDL 155
Query: 281 VPGDLLILT-GNKVLMPCDAVLIEG-SCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQS 338
VPGD + L+ G++V P D L E +DE LTGE+ P +K P+ P T
Sbjct: 156 VPGDTVCLSVGDRV--PADLRLFEAVDLSIDESSLTGETTPCSKVTAPQ-----PAATNG 208
Query: 339 EADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYR-- 396
+ + ++ F GT V KA + VV+ TG N+ G++ + + + L +
Sbjct: 209 DLASRSNIAFMGTLVRCGKA------KGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSM 262
Query: 397 DAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGI-I 455
D + L IG+I + V L G+ E+ ++ + A+P LP +T + +
Sbjct: 263 DLLGKQLSFYSFGIIGII--MLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLAL 320
Query: 456 YAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCD---------- 505
R +KKR I P + G N++C DKTGTLT++ + + + + D
Sbjct: 321 GVMRMVKKRAIVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVG 379
Query: 506 RNGFQE-------VHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW 558
N F E VH F + + A C+ ++ + T+ G P + + A
Sbjct: 380 YNQFGEVIVDGDVVHGFYNPAV---SRIVEAGCVCNDAVIRNNTLMGKPTEGALI-ALAM 435
Query: 559 EMAFSG--DDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTV-IVQEM 615
+M G D+ K ++PFSS + M V V
Sbjct: 436 KMGLDGLQQDYIRKA--------------------------EYPFSSEQKWMAVKCVHRT 469
Query: 616 GGDR--LAFMKGAPERVASFCQPETVPTSFVSELQIYT-TQGFRVIALAYKKLENDH--H 670
DR + FMKGA E+V +C T++ S+ Q T TQ R + K
Sbjct: 470 QQDRPEICFMKGAYEQVIKYC------TTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLR 523
Query: 671 ATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARK 730
L L FLGL+ + + + K + LI++ + MITGD+ +TA+ +A +
Sbjct: 524 VLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583
Query: 731 SGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGS 790
G+ S+ +S S+S G + + ++++
Sbjct: 584 LGLYSK---------------TSQSVS------------GEEIDAMDVQ----------- 605
Query: 791 YHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGA 850
S ++PK+ +F R SP K +++ QK V M GDG
Sbjct: 606 ---------------QLSQIVPKV----AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGV 646
Query: 851 NDCGALKMAHVGISLSEQEASV---ASPFTSKTPNIECVPHLIKEGRAAL--VTSFCMFK 905
ND ALK A +G+++ + V A+ + + + I+EG+ + +F F+
Sbjct: 647 NDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQ 706
Query: 906 YMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYP--KLVPFRPA 963
+ + + + L N L+ Q L+ ++ + G G P K V +P
Sbjct: 707 LSTSIAALTLISLATLMNFPNPLNAMQILWINIIMD---GPPAQSLGVEPVDKDVIRKPP 763
Query: 964 GRLISPPLLLSVIFNILLSLAMHIAGFILV 993
L ++I IL+S + + G + V
Sbjct: 764 RNWKDSILTKNLILKILVSSIIIVCGTLFV 793
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
sapiens]
Length = 888
Score = 142 bits (358), Expect = 2e-33
Identities = 209/870 (24%), Positives = 352/870 (40%), Gaps = 164/870 (18%)
Query: 168 SGLTREEQEIRRLICGPNTIDV-EVTPIWKLLIKEVLNPFYIFQL----FSVCLWFSEDY 222
+GL + E RR G N D+ E P+WK I + NP + L SV + +D
Sbjct: 44 NGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA 103
Query: 223 KEYAFAIIIMSIISISLTVYDLREQSVKLHHLV--ESHNSITVSVCGRKAGVQELESRVL 280
AI+I+ ++ + Y + +L LV E H C R+ ++ +R L
Sbjct: 104 VSITVAILIVVTVAF-VQEYRSEKSLEELSKLVPPECH-------CVREGKLEHTLARDL 155
Query: 281 VPGDLLILT-GNKVLMPCDAVLIEG-SCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQS 338
VPGD + L+ G++V P D L E +DE LTGE+ P +K P+ P T
Sbjct: 156 VPGDTVCLSVGDRV--PADLRLFEAVDLSIDESSLTGETTPCSKVTAPQ-----PAATNG 208
Query: 339 EADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYR-- 396
+ + ++ F GT V KA + VV+ TG N+ G++ + + + L +
Sbjct: 209 DLASRSNIAFMGTLVRCGKA------KGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSM 262
Query: 397 DAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGI-I 455
D + L IG+I + V L G+ E+ ++ + A+P LP +T + +
Sbjct: 263 DLLGKQLSFYSFGIIGII--MLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLAL 320
Query: 456 YAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCD---------- 505
R +KKR I P + G N++C DKTGTLT++ + + + + D
Sbjct: 321 GVMRMVKKRAIVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVG 379
Query: 506 RNGFQE-------VHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW 558
N F E VH F + + A C+ ++ + T+ G P + + A
Sbjct: 380 YNQFGEVIVDGDVVHGFYNPAV---SRIVEAGCVCNDAVIRNNTLMGKPTEGALI-ALAM 435
Query: 559 EMAFSG--DDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTV-IVQEM 615
+M G D+ K ++PFSS + M V V
Sbjct: 436 KMGLDGLQQDYIRKA--------------------------EYPFSSEQKWMAVKCVHRT 469
Query: 616 GGDR--LAFMKGAPERVASFCQPETVPTSFVSELQIYT-TQGFRVIALAYKKLENDH--H 670
DR + FMKGA E+V +C T++ S+ Q T TQ R + K
Sbjct: 470 QQDRPEICFMKGAYEQVIKYC------TTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLR 523
Query: 671 ATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARK 730
L L FLGL+ + + + K + LI++ + MITGD+ +TA+ +A +
Sbjct: 524 VLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583
Query: 731 SGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGS 790
G+ S+ +S S+S G + + ++++
Sbjct: 584 LGLYSK---------------TSQSVS------------GEEIDAMDVQ----------- 605
Query: 791 YHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGA 850
S ++PK+ +F R SP K +++ QK V M GDG
Sbjct: 606 ---------------QLSQIVPKV----AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGV 646
Query: 851 NDCGALKMAHVGISLSEQEASV---ASPFTSKTPNIECVPHLIKEGRAAL--VTSFCMFK 905
ND ALK A +G+++ + V A+ + + + I+EG+ + +F F+
Sbjct: 647 NDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQ 706
Query: 906 YMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYP--KLVPFRPA 963
+ + + + L N L+ Q L+ ++ + G G P K V +P
Sbjct: 707 LSTSIAALTLISLATLMNFPNPLNAMQILWINIIMD---GPPAQSLGVEPVDKDVIRKPP 763
Query: 964 GRLISPPLLLSVIFNILLSLAMHIAGFILV 993
L ++I IL+S + + G + V
Sbjct: 764 RNWKDSILTKNLILKILVSSIIIVCGTLFV 793
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
sapiens]
Length = 919
Score = 142 bits (358), Expect = 2e-33
Identities = 209/870 (24%), Positives = 352/870 (40%), Gaps = 164/870 (18%)
Query: 168 SGLTREEQEIRRLICGPNTIDV-EVTPIWKLLIKEVLNPFYIFQL----FSVCLWFSEDY 222
+GL + E RR G N D+ E P+WK I + NP + L SV + +D
Sbjct: 44 NGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA 103
Query: 223 KEYAFAIIIMSIISISLTVYDLREQSVKLHHLV--ESHNSITVSVCGRKAGVQELESRVL 280
AI+I+ ++ + Y + +L LV E H C R+ ++ +R L
Sbjct: 104 VSITVAILIVVTVAF-VQEYRSEKSLEELSKLVPPECH-------CVREGKLEHTLARDL 155
Query: 281 VPGDLLILT-GNKVLMPCDAVLIEG-SCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQS 338
VPGD + L+ G++V P D L E +DE LTGE+ P +K P+ P T
Sbjct: 156 VPGDTVCLSVGDRV--PADLRLFEAVDLSIDESSLTGETTPCSKVTAPQ-----PAATNG 208
Query: 339 EADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYR-- 396
+ + ++ F GT V KA + VV+ TG N+ G++ + + + L +
Sbjct: 209 DLASRSNIAFMGTLVRCGKA------KGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSM 262
Query: 397 DAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGI-I 455
D + L IG+I + V L G+ E+ ++ + A+P LP +T + +
Sbjct: 263 DLLGKQLSFYSFGIIGII--MLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLAL 320
Query: 456 YAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCD---------- 505
R +KKR I P + G N++C DKTGTLT++ + + + + D
Sbjct: 321 GVMRMVKKRAIVKKLPI-VETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVG 379
Query: 506 RNGFQE-------VHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW 558
N F E VH F + + A C+ ++ + T+ G P + + A
Sbjct: 380 YNQFGEVIVDGDVVHGFYNPAV---SRIVEAGCVCNDAVIRNNTLMGKPTEGALI-ALAM 435
Query: 559 EMAFSG--DDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTV-IVQEM 615
+M G D+ K ++PFSS + M V V
Sbjct: 436 KMGLDGLQQDYIRKA--------------------------EYPFSSEQKWMAVKCVHRT 469
Query: 616 GGDR--LAFMKGAPERVASFCQPETVPTSFVSELQIYT-TQGFRVIALAYKKLENDH--H 670
DR + FMKGA E+V +C T++ S+ Q T TQ R + K
Sbjct: 470 QQDRPEICFMKGAYEQVIKYC------TTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLR 523
Query: 671 ATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARK 730
L L FLGL+ + + + K + LI++ + MITGD+ +TA+ +A +
Sbjct: 524 VLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583
Query: 731 SGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGS 790
G+ S+ +S S+S G + + ++++
Sbjct: 584 LGLYSK---------------TSQSVS------------GEEIDAMDVQ----------- 605
Query: 791 YHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGA 850
S ++PK+ +F R SP K +++ QK V M GDG
Sbjct: 606 ---------------QLSQIVPKV----AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGV 646
Query: 851 NDCGALKMAHVGISLSEQEASV---ASPFTSKTPNIECVPHLIKEGRAAL--VTSFCMFK 905
ND ALK A +G+++ + V A+ + + + I+EG+ + +F F+
Sbjct: 647 NDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQ 706
Query: 906 YMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYP--KLVPFRPA 963
+ + + + L N L+ Q L+ ++ + G G P K V +P
Sbjct: 707 LSTSIAALTLISLATLMNFPNPLNAMQILWINIIMD---GPPAQSLGVEPVDKDVIRKPP 763
Query: 964 GRLISPPLLLSVIFNILLSLAMHIAGFILV 993
L ++I IL+S + + G + V
Sbjct: 764 RNWKDSILTKNLILKILVSSIIIVCGTLFV 793
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo
sapiens]
Length = 994
Score = 124 bits (310), Expect = 7e-28
Identities = 232/1052 (22%), Positives = 396/1052 (37%), Gaps = 179/1052 (17%)
Query: 168 SGLTREEQEIRRLICGPNTIDVEV-TPIWKLLIKEVLNPFYIFQLFSVCL-----WFSED 221
+GLT ++ + G N + E +W+L+I++ + L + C+ WF E
Sbjct: 22 TGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEG 81
Query: 222 YKEYA-----FAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELE 276
+ F I+++ I + + V+ R + L E + + VQ ++
Sbjct: 82 EETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIK 141
Query: 277 SRVLVPGDLL-ILTGNKVLMPCDAVLIEGSCV-VDEGMLTGESIPVTKTPLPKMDSSVPW 334
+R +VPGD++ + G+KV + I+ + + VD+ +LTGES+ V K P D
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDP---- 197
Query: 335 KTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQL 394
++ K+++LF GT + KA +V TG T G + + + L
Sbjct: 198 --RAVNQDKKNMLFSGTNIAAGKAL------GIVATTGVGTEIGKIRDQMAATEQDKTPL 249
Query: 395 YRDAIRFLLCLVGTATIGMIYTLCVYVLS---GEPPEEV------------VRKALDVIT 439
+ F G +I +CV V G + V + A+ +
Sbjct: 250 QQKLDEF-----GEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAV 304
Query: 440 IAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLW 499
A+P LPA +TT + RR+ K+ S + G +++C DKTGTLT + + +
Sbjct: 305 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364
Query: 500 GVVSCDR--------NGFQEVHSFAS--GQAL----PWGP--------LCAAMASCHSLI 537
+ D+ N F S + G+ L P P L A C+
Sbjct: 365 KMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSS 424
Query: 538 LLDGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAIL 596
L +G + K+ EAT + + ++ ++ V+ + V + +
Sbjct: 425 LDFNEAKG--VYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482
Query: 597 HQFPFSSALQRMTVIVQEMGGDRLA-----FMKGAPERVASFCQPETVPTSFV------- 644
FS + M+V R A F+KGAPE V C V T+ V
Sbjct: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVK 542
Query: 645 ----SELQIYTT--QGFRVIALAYKKLENDHHATTLTRET----VESDLIFLGLLILENR 694
+ ++ + T R +ALA + L E+DL F+G++ + +
Sbjct: 543 EKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDP 602
Query: 695 LKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSA 754
++E ++ A IR +MITGDN TAI + R+ G+ E++
Sbjct: 603 PRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENE---------------- 646
Query: 755 SISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKI 814
EV+D+ A TG+ F + +
Sbjct: 647 --------------------------EVADR--------AYTGREFDDLPLAEQR---EA 669
Query: 815 LINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASV 872
FAR+ P KS +VE Q D M GDG ND ALK A +GI++ A
Sbjct: 670 CRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKT 729
Query: 873 ASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSN 930
AS N + ++EGRA +Y+ ++ + V + L +L
Sbjct: 730 ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIP 789
Query: 931 YQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGF 990
Q L+ +L L + N P L R PL+ +F +++ ++ G
Sbjct: 790 VQLLWVNLVTDGLPATALGFNP--PDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYV-GA 846
Query: 991 ILVQRQPW------------YSVEIH-SACTVQNESISELTMSP-TAPEKMESNSTFTSF 1036
V W YS H CT N + APE M T
Sbjct: 847 ATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPM----TMALS 902
Query: 1037 ENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFAD-IPELY 1095
T+ +N ++ R P + N + + + + + IL+ D +P ++
Sbjct: 903 VLVTIEMCNALNSLS-----ENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIF 957
Query: 1096 --RRLDLLCTPVLWRASIVIMLSLNFIVSLVA 1125
R LDL ++ + S+ + + L+ I+ VA
Sbjct: 958 KLRALDLTQWLMVLKISLPV-IGLDEILKFVA 988
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo
sapiens]
Length = 1001
Score = 124 bits (310), Expect = 7e-28
Identities = 232/1052 (22%), Positives = 396/1052 (37%), Gaps = 179/1052 (17%)
Query: 168 SGLTREEQEIRRLICGPNTIDVEV-TPIWKLLIKEVLNPFYIFQLFSVCL-----WFSED 221
+GLT ++ + G N + E +W+L+I++ + L + C+ WF E
Sbjct: 22 TGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEG 81
Query: 222 YKEYA-----FAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELE 276
+ F I+++ I + + V+ R + L E + + VQ ++
Sbjct: 82 EETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIK 141
Query: 277 SRVLVPGDLL-ILTGNKVLMPCDAVLIEGSCV-VDEGMLTGESIPVTKTPLPKMDSSVPW 334
+R +VPGD++ + G+KV + I+ + + VD+ +LTGES+ V K P D
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDP---- 197
Query: 335 KTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQL 394
++ K+++LF GT + KA +V TG T G + + + L
Sbjct: 198 --RAVNQDKKNMLFSGTNIAAGKAL------GIVATTGVGTEIGKIRDQMAATEQDKTPL 249
Query: 395 YRDAIRFLLCLVGTATIGMIYTLCVYVLS---GEPPEEV------------VRKALDVIT 439
+ F G +I +CV V G + V + A+ +
Sbjct: 250 QQKLDEF-----GEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAV 304
Query: 440 IAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLW 499
A+P LPA +TT + RR+ K+ S + G +++C DKTGTLT + + +
Sbjct: 305 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364
Query: 500 GVVSCDR--------NGFQEVHSFAS--GQAL----PWGP--------LCAAMASCHSLI 537
+ D+ N F S + G+ L P P L A C+
Sbjct: 365 KMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSS 424
Query: 538 LLDGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAIL 596
L +G + K+ EAT + + ++ ++ V+ + V + +
Sbjct: 425 LDFNEAKG--VYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482
Query: 597 HQFPFSSALQRMTVIVQEMGGDRLA-----FMKGAPERVASFCQPETVPTSFV------- 644
FS + M+V R A F+KGAPE V C V T+ V
Sbjct: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVK 542
Query: 645 ----SELQIYTT--QGFRVIALAYKKLENDHHATTLTRET----VESDLIFLGLLILENR 694
+ ++ + T R +ALA + L E+DL F+G++ + +
Sbjct: 543 EKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDP 602
Query: 695 LKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSA 754
++E ++ A IR +MITGDN TAI + R+ G+ E++
Sbjct: 603 PRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENE---------------- 646
Query: 755 SISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKI 814
EV+D+ A TG+ F + +
Sbjct: 647 --------------------------EVADR--------AYTGREFDDLPLAEQR---EA 669
Query: 815 LINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASV 872
FAR+ P KS +VE Q D M GDG ND ALK A +GI++ A
Sbjct: 670 CRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKT 729
Query: 873 ASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSN 930
AS N + ++EGRA +Y+ ++ + V + L +L
Sbjct: 730 ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIP 789
Query: 931 YQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGF 990
Q L+ +L L + N P L R PL+ +F +++ ++ G
Sbjct: 790 VQLLWVNLVTDGLPATALGFNP--PDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYV-GA 846
Query: 991 ILVQRQPW------------YSVEIH-SACTVQNESISELTMSP-TAPEKMESNSTFTSF 1036
V W YS H CT N + APE M T
Sbjct: 847 ATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPM----TMALS 902
Query: 1037 ENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFAD-IPELY 1095
T+ +N ++ R P + N + + + + + IL+ D +P ++
Sbjct: 903 VLVTIEMCNALNSLS-----ENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIF 957
Query: 1096 --RRLDLLCTPVLWRASIVIMLSLNFIVSLVA 1125
R LDL ++ + S+ + + L+ I+ VA
Sbjct: 958 KLRALDLTQWLMVLKISLPV-IGLDEILKFVA 988
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 120 bits (301), Expect = 8e-27
Identities = 210/929 (22%), Positives = 369/929 (39%), Gaps = 153/929 (16%)
Query: 126 LKVRCIKVQKIRYVWNYLEGQFQKIGSLEDW-LSSAKIHQKFGSGL------TREEQEIR 178
LK C++++K + + +FQK L+D LS+ ++ +K+G+ + TR + +
Sbjct: 34 LKNNCLELKKKNH-----KEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLA 88
Query: 179 RLICGPNTIDV-EVTPIWKLLIKEVLNPFYIFQLFSVCL-W------FSEDYKE-----Y 225
R GPN++ + TP +K+++ F I L W +S D Y
Sbjct: 89 R--DGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVY 146
Query: 226 AFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITV--SVCGRKAGVQELESRVLVPG 283
++ + +I + Y Q K +++ S N + ++ R + + + S LV G
Sbjct: 147 LGCVLGLVVILTGIFAY---YQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVG 203
Query: 284 DLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYK 343
D++ + G + VL C VD LTGES P ++ + P +T
Sbjct: 204 DIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSS--EFTHENPLET------- 254
Query: 344 RHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLL 403
+++ F T ++ GTV +V+ TG T G + + + F+
Sbjct: 255 KNICFYSTTCLE------GTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVH 308
Query: 404 CLVGTA-TIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLK 462
+ G A +IG+++ + L + + ++ + +I VP L A +T + +R+
Sbjct: 309 IVAGVAVSIGILFFIIAVSLKYQVLDSIIF-LIGIIVANVPEGLLATVTVTLSLTAKRMA 367
Query: 463 KRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLD---LWGVVSCDRNGFQEVHS--FAS 517
K+ + + + G +++C DKTGTLT++ + LW E HS
Sbjct: 368 KKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFD 427
Query: 518 GQALPWGPLCAAMASCH---------SLILLDGTIQGDPLDLKMFEATTWEMAFSGDDFH 568
+ W L + C+ ++ ++ + GD + + + + GD
Sbjct: 428 QSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLK---FSEVILGDVME 484
Query: 569 IKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEMGGDR-LAFMKGAP 627
I+ K R +++P F ++ Q + + G R L MKGAP
Sbjct: 485 IR---------KRNRKVAEIP---------FNSTNKFQLSIHEMDDPHGKRFLMVMKGAP 526
Query: 628 ERVASFCQP-----ETVPTSFVSELQIYTTQ------GFRVIALAYKKLENDHHATTLTR 676
ER+ C E P + +T G RV+ + L D T +
Sbjct: 527 ERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSF 586
Query: 677 ET-----VESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKS 731
+ S+L F+GLL + + + + + SA I+ +M+TGD+ TA +A+
Sbjct: 587 DIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSV 646
Query: 732 GMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSY 791
G++S AN T A VE+ +N RD +
Sbjct: 647 GIIS---------ANSETVEDIAHRLNIAVEQ------------VNKRDAKAA------- 678
Query: 792 HFALTGKSFHVISQHFSSLLPKILIN--GTIFARMSPGQKSSLVEEFQKLDYFVGMCGDG 849
+TG +S S L +IL N +FAR SP QK +VE Q+ D V + GDG
Sbjct: 679 --VVTGMELKDMS---SEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDG 733
Query: 850 ANDCGALKMAHVGISL---SEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKY 906
ND ALK A +GI++ A A+ N + ++EGR F K
Sbjct: 734 VNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLI----FDNLKK 789
Query: 907 MALYSMIQYVGVL---LLYWETN---SLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPF 960
YS+ + + L L+Y + LF DL + + + A ++
Sbjct: 790 TIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNR 849
Query: 961 RP----AGRLISPPLLLSVIFNILLSLAM 985
+P RL++ PL + +I L A+
Sbjct: 850 KPRHKNKDRLVNQPLAVYSYLHIGLMQAL 878
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 119 bits (297), Expect = 2e-26
Identities = 177/797 (22%), Positives = 324/797 (40%), Gaps = 112/797 (14%)
Query: 146 QFQKIGSLEDW-LSSAKIHQKFGSGLTREEQEIRRLIC----GPNTIDVE-VTPIWKLLI 199
+ +K S++D LS ++H+K+G+ L+R R GPN + TP W
Sbjct: 34 ELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFC 93
Query: 200 KEVLNPFYIFQLFSVCLWF----------SEDYKEYAFAIIIMSIISISLTVYDLREQSV 249
+++ F + L F E + + +++S + I + +++
Sbjct: 94 RQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA- 152
Query: 250 KLHHLVESHNSITV--SVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEGS-C 306
K ++ES ++ ++ R + + +V GDL+ + G + P D +I + C
Sbjct: 153 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRI-PADLRIISANGC 211
Query: 307 VVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRA 366
VD LTGES P T++P + P +T R++ F T ++ GT R
Sbjct: 212 KVDNSSLTGESEPQTRSP--DFTNENPLET-------RNIAFFSTNCVE------GTARG 256
Query: 367 VVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTAT-IGMIYTLCVYVLSGE 425
+V+ TG T G + + + + F+ + G A +G+ + + +L
Sbjct: 257 IVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYT 316
Query: 426 PPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCF 485
E V+ + +I VP L A +T + +R+ ++ + + + G + +C
Sbjct: 317 WLEAVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICS 375
Query: 486 DKTGTLTRDGL---DLW---GVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILL 539
DKTGTLT++ + +W + D Q SF A W L C+ +
Sbjct: 376 DKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSA-TWLALSRIAGLCNRAV-- 432
Query: 540 DGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQF 599
Q + +L + + A +GD A ++ C + + E A + +
Sbjct: 433 ---FQANQENLPIL-----KRAVAGD----ASESALLKCIELCCGSVKEMRERYAKIVEI 480
Query: 600 PFSSALQRMTVIVQEMG---GDRLAFMKGAPERVASFC---------QP--ETVPTSFVS 645
PF+S + I + L MKGAPER+ C QP E + +F +
Sbjct: 481 PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN 540
Query: 646 ELQIYTTQGFRVIALAYKKLENDHHATTLTRETVE-----SDLIFLGLLILENRLKEETK 700
G RV+ + L ++ +T + +L F+GL+ + + +
Sbjct: 541 AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP 600
Query: 701 PVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTL 760
+ + SA I+ +M+TGD+ TA +A+ G++S E NET +A ++ +
Sbjct: 601 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIIS--------EGNETVEDIAARLNIPV 652
Query: 761 VEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTI 820
+ +N RD + GS +T + I ++ + + +
Sbjct: 653 -------------SQVNPRDAKACV-VHGSDLKDMTSEQLDDILKYHTEI---------V 689
Query: 821 FARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASV---ASPFT 877
FAR SP QK +VE Q+ V + GDG ND ALK A +G+++ + V A+
Sbjct: 690 FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMI 749
Query: 878 SKTPNIECVPHLIKEGR 894
N + ++EGR
Sbjct: 750 LLDDNFASIVTGVEEGR 766
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
Length = 992
Score = 119 bits (297), Expect = 2e-26
Identities = 177/797 (22%), Positives = 324/797 (40%), Gaps = 112/797 (14%)
Query: 146 QFQKIGSLEDW-LSSAKIHQKFGSGLTREEQEIRRLIC----GPNTIDVE-VTPIWKLLI 199
+ +K S++D LS ++H+K+G+ L+R R GPN + TP W
Sbjct: 3 ELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFC 62
Query: 200 KEVLNPFYIFQLFSVCLWF----------SEDYKEYAFAIIIMSIISISLTVYDLREQSV 249
+++ F + L F E + + +++S + I + +++
Sbjct: 63 RQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA- 121
Query: 250 KLHHLVESHNSITV--SVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEGS-C 306
K ++ES ++ ++ R + + +V GDL+ + G + P D +I + C
Sbjct: 122 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRI-PADLRIISANGC 180
Query: 307 VVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRA 366
VD LTGES P T++P + P +T R++ F T ++ GT R
Sbjct: 181 KVDNSSLTGESEPQTRSP--DFTNENPLET-------RNIAFFSTNCVE------GTARG 225
Query: 367 VVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTAT-IGMIYTLCVYVLSGE 425
+V+ TG T G + + + + F+ + G A +G+ + + +L
Sbjct: 226 IVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYT 285
Query: 426 PPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCF 485
E V+ + +I VP L A +T + +R+ ++ + + + G + +C
Sbjct: 286 WLEAVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICS 344
Query: 486 DKTGTLTRDGL---DLW---GVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILL 539
DKTGTLT++ + +W + D Q SF A W L C+ +
Sbjct: 345 DKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSA-TWLALSRIAGLCNRAV-- 401
Query: 540 DGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQF 599
Q + +L + + A +GD A ++ C + + E A + +
Sbjct: 402 ---FQANQENLPIL-----KRAVAGD----ASESALLKCIELCCGSVKEMRERYAKIVEI 449
Query: 600 PFSSALQRMTVIVQEMG---GDRLAFMKGAPERVASFC---------QP--ETVPTSFVS 645
PF+S + I + L MKGAPER+ C QP E + +F +
Sbjct: 450 PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN 509
Query: 646 ELQIYTTQGFRVIALAYKKLENDHHATTLTRETVE-----SDLIFLGLLILENRLKEETK 700
G RV+ + L ++ +T + +L F+GL+ + + +
Sbjct: 510 AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP 569
Query: 701 PVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTL 760
+ + SA I+ +M+TGD+ TA +A+ G++S E NET +A ++ +
Sbjct: 570 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIIS--------EGNETVEDIAARLNIPV 621
Query: 761 VEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTI 820
+ +N RD + GS +T + I ++ + + +
Sbjct: 622 -------------SQVNPRDAKACV-VHGSDLKDMTSEQLDDILKYHTEI---------V 658
Query: 821 FARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASV---ASPFT 877
FAR SP QK +VE Q+ V + GDG ND ALK A +G+++ + V A+
Sbjct: 659 FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMI 718
Query: 878 SKTPNIECVPHLIKEGR 894
N + ++EGR
Sbjct: 719 LLDDNFASIVTGVEEGR 735
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 119 bits (297), Expect = 2e-26
Identities = 177/797 (22%), Positives = 324/797 (40%), Gaps = 112/797 (14%)
Query: 146 QFQKIGSLEDW-LSSAKIHQKFGSGLTREEQEIRRLIC----GPNTIDVE-VTPIWKLLI 199
+ +K S++D LS ++H+K+G+ L+R R GPN + TP W
Sbjct: 34 ELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFC 93
Query: 200 KEVLNPFYIFQLFSVCLWF----------SEDYKEYAFAIIIMSIISISLTVYDLREQSV 249
+++ F + L F E + + +++S + I + +++
Sbjct: 94 RQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA- 152
Query: 250 KLHHLVESHNSITV--SVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEGS-C 306
K ++ES ++ ++ R + + +V GDL+ + G + P D +I + C
Sbjct: 153 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRI-PADLRIISANGC 211
Query: 307 VVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRA 366
VD LTGES P T++P + P +T R++ F T ++ GT R
Sbjct: 212 KVDNSSLTGESEPQTRSP--DFTNENPLET-------RNIAFFSTNCVE------GTARG 256
Query: 367 VVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTAT-IGMIYTLCVYVLSGE 425
+V+ TG T G + + + + F+ + G A +G+ + + +L
Sbjct: 257 IVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYT 316
Query: 426 PPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCF 485
E V+ + +I VP L A +T + +R+ ++ + + + G + +C
Sbjct: 317 WLEAVIF-LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICS 375
Query: 486 DKTGTLTRDGL---DLW---GVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILL 539
DKTGTLT++ + +W + D Q SF A W L C+ +
Sbjct: 376 DKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSA-TWLALSRIAGLCNRAV-- 432
Query: 540 DGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQF 599
Q + +L + + A +GD A ++ C + + E A + +
Sbjct: 433 ---FQANQENLPIL-----KRAVAGD----ASESALLKCIELCCGSVKEMRERYAKIVEI 480
Query: 600 PFSSALQRMTVIVQEMG---GDRLAFMKGAPERVASFC---------QP--ETVPTSFVS 645
PF+S + I + L MKGAPER+ C QP E + +F +
Sbjct: 481 PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN 540
Query: 646 ELQIYTTQGFRVIALAYKKLENDHHATTLTRETVE-----SDLIFLGLLILENRLKEETK 700
G RV+ + L ++ +T + +L F+GL+ + + +
Sbjct: 541 AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP 600
Query: 701 PVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTL 760
+ + SA I+ +M+TGD+ TA +A+ G++S E NET +A ++ +
Sbjct: 601 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIIS--------EGNETVEDIAARLNIPV 652
Query: 761 VEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTI 820
+ +N RD + GS +T + I ++ + + +
Sbjct: 653 -------------SQVNPRDAKACV-VHGSDLKDMTSEQLDDILKYHTEI---------V 689
Query: 821 FARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASV---ASPFT 877
FAR SP QK +VE Q+ V + GDG ND ALK A +G+++ + V A+
Sbjct: 690 FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMI 749
Query: 878 SKTPNIECVPHLIKEGR 894
N + ++EGR
Sbjct: 750 LLDDNFASIVTGVEEGR 766
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 119 bits (297), Expect = 2e-26
Identities = 173/782 (22%), Positives = 312/782 (39%), Gaps = 107/782 (13%)
Query: 157 LSSAKIHQKFGSGLTR--EEQEIRRLIC--GPNTIDVE-VTPIWKLLIKEVLNPFYI--- 208
L+ ++ K+ LT+ Q + ++ GPNT+ TP W K++ F +
Sbjct: 54 LTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLW 113
Query: 209 ------FQLFSVCLWFSED-YKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSI 261
F +S+ ++F+E+ K+ + I++S++ I + +++ K ++ES ++
Sbjct: 114 TGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEA-KSSKIMESFKNM 172
Query: 262 TVSVCGRKAGVQELESRV--LVPGDLLILTGNKVLMPCDAVLIEGS-CVVDEGMLTGESI 318
G ++++ V +V GDL+ + G +P D LI C VD LTGES
Sbjct: 173 VPQQALVIRGGEKMQINVQEVVLGDLVEIKGGD-RVPADLRLISAQGCKVDNSSLTGESE 231
Query: 319 PVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKG 378
P +++P P +T R++ F T ++ GT R +V+ TG +T G
Sbjct: 232 PQSRSP--DFTHENPLET-------RNICFFSTNCVE------GTARGIVIATGDSTVMG 276
Query: 379 DLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVI 438
+ + + F+ + A + + +L G E + + +I
Sbjct: 277 RIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGII 336
Query: 439 TIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGL-- 496
VP L A +T + +R+ ++ + + + G + +C DKTGTLT++ +
Sbjct: 337 VANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTV 396
Query: 497 -DLW---GVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKM 552
+W V D Q +F W L C+ D + L +
Sbjct: 397 AHMWFDMTVYEADTTEEQTGKTFTKSSD-TWFMLARIAGLCNR---ADFKANQEILPIAK 452
Query: 553 FEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQ-RMTVI 611
ATT + + + +K + V R + E PF+S + +M++
Sbjct: 453 -RATTGD---ASESALLKFIEQSYSSVAEMREKNPKVAE-------IPFNSTNKYQMSIH 501
Query: 612 VQEMGGD-RLAFMKGAPERVASFCQP-----------ETVPTSFVSELQIYTTQGFRVIA 659
++E + MKGAPER+ FC + + +F + G RV+
Sbjct: 502 LREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLG 561
Query: 660 LAYKKLENDHHA----TTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVM 715
+ L + T +L F+GL+ + + + + + SA I+ +M
Sbjct: 562 FCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIM 621
Query: 716 ITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNY 775
+TGD+ TA +A+ G++SE + A E IS K I+ +
Sbjct: 622 VTGDHPITAKAIAKGVGIISEGTET----AEEVAARLKIPISKVDASAAKAIVVHGAE-- 675
Query: 776 INIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEE 835
++D + K I Q+ + +FAR SP QK +VE
Sbjct: 676 --LKD--------------IQSKQLDQILQNHPEI---------VFARTSPQQKLIIVEG 710
Query: 836 FQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASV---ASPFTSKTPNIECVPHLIKE 892
Q+L V + GDG ND ALK A +GI++ + V A+ N + ++E
Sbjct: 711 CQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEE 770
Query: 893 GR 894
GR
Sbjct: 771 GR 772
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 117 bits (294), Expect = 5e-26
Identities = 228/1061 (21%), Positives = 400/1061 (37%), Gaps = 182/1061 (17%)
Query: 168 SGLTREEQEIRRLICGPNTIDVEV-TPIWKLLIKEVLNPFYIFQLFSVCL-----WFSED 221
+GL+ E+ + + G N + E + +L+I++ + L + C+ WF E
Sbjct: 22 TGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEG 81
Query: 222 YKEYA-----FAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELE 276
+ F I+++ + + + V+ R + L E + + VQ ++
Sbjct: 82 EETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIK 141
Query: 277 SRVLVPGDLL-ILTGNKVLMPCDAVLIEGSCV-VDEGMLTGESIPVTKTPLPKMDSSVPW 334
++ +VPGD++ I G+KV I+ + + VD+ +LTGES+ V K P D
Sbjct: 142 AKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDP---- 197
Query: 335 KTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQL 394
++ K+++LF GT + KA VV+ TG NT G + ++ + L
Sbjct: 198 --RAVNQDKKNMLFSGTNIAAGKAM------GVVVATGVNTEIGKIRDEMVATEQERTPL 249
Query: 395 YRDAIRFLLCLVGTATIGMIYTLCVYVLS---GEPPEEV-----VRKALDVITIAV---- 442
+ F G +I +C+ V G + V +R A+ IAV
Sbjct: 250 QQKLDEF-----GEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 304
Query: 443 ---PPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLW 499
P LPA +TT + RR+ K+ S + G +++C DKTGTLT + + +
Sbjct: 305 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364
Query: 500 GVV--------SCDRNGFQ----------EVHS----FASGQALPWGPLCAAMASCHSLI 537
+ +C N F EVH Q L A C+
Sbjct: 365 RMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 424
Query: 538 LLDGTIQGDPLDLKMFEATTWEMAFSGD-----DFHIKGVPAHAMVVKPCRTASQVPVEG 592
L +G + K+ EAT + + D +KG+ ++ + V +
Sbjct: 425 LDYNEAKG--VYEKVGEATETALTCLVEKMNVFDTELKGLSK----IERANACNSVIKQL 478
Query: 593 IAILHQFPFSSALQRMTVIVQEMGGDRLA----FMKGAPERVASFCQ-----PETVPTSF 643
+ FS + M+V R + F+KGAPE V C VP +
Sbjct: 479 MKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTS 538
Query: 644 VSELQIYT--------TQGFRVIALAYK----KLENDHHATTLTRETVESDLIFLGLLIL 691
+ +I + + R +ALA + E H + E++L F+G + +
Sbjct: 539 GVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGM 598
Query: 692 ENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGS 751
+ + E ++ A IR +MITGDN TA+ + R+ G+ + +
Sbjct: 599 LDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDE------------- 645
Query: 752 SSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLL 811
+V+ K A TG+ F ++ S
Sbjct: 646 -----------------------------DVTSK--------AFTGREFDELNP---SAQ 665
Query: 812 PKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QE 869
+N FAR+ P KS +VE Q D M GDG ND ALK A +GI++
Sbjct: 666 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAV 725
Query: 870 ASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNS 927
A AS N + ++EGRA +Y+ ++ + V + L +
Sbjct: 726 AKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEA 785
Query: 928 LSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHI 987
L Q L+ +L L + N P L R PL+ +F L++ ++
Sbjct: 786 LIPVQLLWVNLVTDGLPATALGFNP--PDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYV 843
Query: 988 AGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKMESNSTFTS-----FENTTVW 1042
G V W+ + V +S + E N F FE+
Sbjct: 844 -GAATVGAAAWWFIAADGGPRVSFYQLSHFL------QCKEDNPDFEGVDCAIFESPYPM 896
Query: 1043 FLGTINCITVAL------VFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFAD-IPELY 1095
+ +T+ + + R P + N V + + + + IL+ + +P ++
Sbjct: 897 TMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIF 956
Query: 1096 RRLDLLCTP--VLWRASIVIML---SLNFIVSLVAEEAVIE 1131
+ L T ++ + S+ ++L +L F+ E A++E
Sbjct: 957 QITPLNVTQWLMVLKISLPVILMDETLKFVARNYLEPAILE 997
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
sapiens]
Length = 1042
Score = 116 bits (291), Expect = 1e-25
Identities = 204/914 (22%), Positives = 347/914 (37%), Gaps = 159/914 (17%)
Query: 168 SGLTREEQEIRRLICGPNTIDVEV-TPIWKLLIKEVLNPFYIFQLFSVCL-----WFSED 221
+GL+ E+ + + G N + E + +L+I++ + L + C+ WF E
Sbjct: 22 TGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEG 81
Query: 222 YKEYA-----FAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELE 276
+ F I+++ + + + V+ R + L E + + VQ ++
Sbjct: 82 EETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIK 141
Query: 277 SRVLVPGDLL-ILTGNKVLMPCDAVLIEGSCV-VDEGMLTGESIPVTKTPLPKMDSSVPW 334
++ +VPGD++ I G+KV I+ + + VD+ +LTGES+ V K P D
Sbjct: 142 AKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDP---- 197
Query: 335 KTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQL 394
++ K+++LF GT + KA VV+ TG NT G + ++ + L
Sbjct: 198 --RAVNQDKKNMLFSGTNIAAGKAM------GVVVATGVNTEIGKIRDEMVATEQERTPL 249
Query: 395 YRDAIRFLLCLVGTATIGMIYTLCVYVLS---GEPPEEV-----VRKALDVITIAV---- 442
+ F G +I +C+ V G + V +R A+ IAV
Sbjct: 250 QQKLDEF-----GEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 304
Query: 443 ---PPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLW 499
P LPA +TT + RR+ K+ S + G +++C DKTGTLT + + +
Sbjct: 305 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364
Query: 500 GVV--------SCDRNGFQ----------EVHS----FASGQALPWGPLCAAMASCHSLI 537
+ +C N F EVH Q L A C+
Sbjct: 365 RMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 424
Query: 538 LLDGTIQGDPLDLKMFEATTWEMAFSGD-----DFHIKGVPAHAMVVKPCRTASQVPVEG 592
L +G + K+ EAT + + D +KG+ ++ + V +
Sbjct: 425 LDYNEAKG--VYEKVGEATETALTCLVEKMNVFDTELKGLSK----IERANACNSVIKQL 478
Query: 593 IAILHQFPFSSALQRMTVIVQEMGGDRLA----FMKGAPERVASFCQ-----PETVPTSF 643
+ FS + M+V R + F+KGAPE V C VP +
Sbjct: 479 MKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTS 538
Query: 644 VSELQIYT--------TQGFRVIALAYK----KLENDHHATTLTRETVESDLIFLGLLIL 691
+ +I + + R +ALA + E H + E++L F+G + +
Sbjct: 539 GVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGM 598
Query: 692 ENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGS 751
+ + E ++ A IR +MITGDN TA+ + R+ G+ + +
Sbjct: 599 LDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDE------------- 645
Query: 752 SSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLL 811
+V+ K A TG+ F ++ S
Sbjct: 646 -----------------------------DVTSK--------AFTGREFDELNP---SAQ 665
Query: 812 PKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QE 869
+N FAR+ P KS +VE Q D M GDG ND ALK A +GI++
Sbjct: 666 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAV 725
Query: 870 ASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNS 927
A AS N + ++EGRA +Y+ ++ + V + L +
Sbjct: 726 AKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEA 785
Query: 928 LSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHI 987
L Q L+ +L L + N P L R PL+ +F L++ ++
Sbjct: 786 LIPVQLLWVNLVTDGLPATALGFNP--PDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYV 843
Query: 988 AGFILVQRQPWYSV 1001
G V W+ +
Sbjct: 844 -GAATVGAAAWWFI 856
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 112 bits (281), Expect = 2e-24
Identities = 178/798 (22%), Positives = 313/798 (39%), Gaps = 119/798 (14%)
Query: 148 QKIGSLEDWLSSAKIHQKFGS----GLTREEQEIRRLICGPNTIDVE-VTPIWKLLIKEV 202
+++ E +S ++ +K+ + GLT + + GPN + TP W +++
Sbjct: 27 KEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQL 86
Query: 203 LNPFYIFQLFSVCLWF-------------SEDYKEYAFAIIIMSIISISLTVYDLREQSV 249
F I L F S D + + II+ + Y Q
Sbjct: 87 FGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYY----QEA 142
Query: 250 KLHHLVESHNSITV--SVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEG-SC 306
K ++ES ++ ++ R+ ++ + +V GDL+ + G +P D +I C
Sbjct: 143 KSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGD-RVPADLRIISAHGC 201
Query: 307 VVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRA 366
VD LTGES P T++P D+ P +T R++ F T ++ GT R
Sbjct: 202 KVDNSSLTGESEPQTRSPDCTHDN--PLET-------RNITFFSTNCVE------GTARG 246
Query: 367 VVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEP 426
VV+ TG T G + + + + F+ + G A + + ++ G
Sbjct: 247 VVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYT 306
Query: 427 PEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFD 486
E V + +I VP L A +T + +R+ ++ + + + G + +C D
Sbjct: 307 WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD 366
Query: 487 KTGTLTRDGL---DLW---GVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLD 540
KTGTLT++ + +W + D Q SF + W L C+ +
Sbjct: 367 KTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSF-DKSSHTWVALSHIAGLCNRAVFKG 425
Query: 541 GTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFP 600
G P+ + E A +K + + VK R ++ E P
Sbjct: 426 GQ-DNIPVLKRDVAGDASESAL------LKCIELSSGSVKLMRERNKKVAE-------IP 471
Query: 601 FSSALQ-RMTVIVQEMGGDR--LAFMKGAPERVASFC---------QP--ETVPTSFVSE 646
F+S + ++++ E D L MKGAPER+ C QP E + +F +
Sbjct: 472 FNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNA 531
Query: 647 LQIYTTQGFRVIALAYKKLENDHHATTLTRET-----VESDLIFLGLLILENRLKEETKP 701
G RV+ + L + + +L F+GL+ + + +
Sbjct: 532 YLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPD 591
Query: 702 VLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLV 761
+ + SA I+ +M+TGD+ TA +A+ G++S E NET +A ++ +
Sbjct: 592 AVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIIS--------EGNETVEDIAARLNIPV- 642
Query: 762 EEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGT-- 819
+ +N RD + + G + S + +IL N T
Sbjct: 643 ------------SQVNPRDAKA---------CVIHGTD---LKDFTSEQIDEILQNHTEI 678
Query: 820 IFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASV---ASPF 876
+FAR SP QK +VE Q+ V + GDG ND ALK A +G+++ + V A+
Sbjct: 679 VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADM 738
Query: 877 TSKTPNIECVPHLIKEGR 894
N + ++EGR
Sbjct: 739 ILLDDNFASIVTGVEEGR 756
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 112 bits (281), Expect = 2e-24
Identities = 191/872 (21%), Positives = 340/872 (38%), Gaps = 169/872 (19%)
Query: 168 SGLTREEQEIRRLICGPNTIDVEVT-PIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYA 226
+GL+ RRL G N + + P+WK + + NP + L S + S KEY
Sbjct: 75 TGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALV--SVLTKEYE 132
Query: 227 FAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSV-----CGRKAGVQELESRVLV 281
A+ I + + + +TV ++E + +S +T V C R+ +Q L +R LV
Sbjct: 133 DAVSIATAVLVVVTVAFIQE-----YRSEKSLEELTKMVPPECNCLREGKLQHLLARELV 187
Query: 282 PGDLLILT-GNKVLMPCDAVLIEGS-CVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSE 339
PGD++ L+ G+++ P D L E + +VDE TGE+ P +KT P +
Sbjct: 188 PGDVVSLSIGDRI--PADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGG-------D 238
Query: 340 ADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYR--D 397
+++F GT V + + VV+ TG ++ G++ + + + L + D
Sbjct: 239 LTTLSNIVFMGTLVQYGRG------QGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMD 292
Query: 398 AIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYA 457
+ L L IG+I + + G+ + + + A+P LP + ++
Sbjct: 293 RLGKQLTLFSFGIIGLI--MLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLG 350
Query: 458 QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFAS 517
R+ K+ + + G +++C DKTGTLT + + + +V+ D +
Sbjct: 351 VLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYD 410
Query: 518 GQA----------------LPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTWEMA 561
GQ + G L A ++ ++ + G P E +A
Sbjct: 411 GQGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPT-----EGALMALA 465
Query: 562 FSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEMGGDR-- 619
D IK ++ + K + PFSS + M V D+
Sbjct: 466 MKMDLSDIK----NSYIRK----------------KEIPFSSEQKWMAVKCSLKTEDQED 505
Query: 620 LAFMKGAPERVASFCQPET---VPTSFVSELQIYTTQ--------GFRVIALAYKKLEND 668
+ FMKGA E V +C +P + + + Q G RV+ALA
Sbjct: 506 IYFMKGALEEVIRYCTMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALA------- 558
Query: 669 HHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVA 728
L R L FLGL+ + + + K ++ L + + MITGD L+TA+ +
Sbjct: 559 -SGPELGR------LTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIG 611
Query: 729 RKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGRE 788
R G L K M G + + + + E++D+ +
Sbjct: 612 RNIG---------------------------LCNGKLQAMSGEEVDSVE-KGELADRVGK 643
Query: 789 GSYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGD 848
S F R SP K +++ Q+ V M GD
Sbjct: 644 VSVFF-----------------------------RTSPKHKLKIIKALQESGAIVAMTGD 674
Query: 849 GANDCGALKMAHVGISLSEQEASV---ASPFTSKTPNIECVPHLIKEGRAAL--VTSFCM 903
G ND ALK A +GI++ + V A+ + + + ++EG+ + +F
Sbjct: 675 GVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVR 734
Query: 904 FKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYP-KLVPFRP 962
F+ S + + + ++ + L+ Q L+ ++ + G G P FR
Sbjct: 735 FQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMD---GPPAQSLGVEPVDKDAFRQ 791
Query: 963 AGRLISPPLL-LSVIFNILLSLAMHIAGFILV 993
R + +L ++I IL+S A+ I+G + +
Sbjct: 792 PPRSVRDTILSRALILKILMSAAIIISGTLFI 823
>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
Length = 1035
Score = 111 bits (278), Expect = 4e-24
Identities = 193/886 (21%), Positives = 329/886 (37%), Gaps = 164/886 (18%)
Query: 274 ELESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVP 333
++ + LV GDL+ + G + +L C VD LTGES P T++P +S P
Sbjct: 190 QINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHES--P 247
Query: 334 WKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDL------VRSILYP 387
+T R++ F T ++ GTV+ +V+ TG T G + V + P
Sbjct: 248 LET-------RNIAFFSTMCLE------GTVQGLVVNTGDRTIIGRIASLASGVENEKTP 294
Query: 388 KPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALP 447
+ + + D I L L G I +C+ G + + ++ VP L
Sbjct: 295 IAIEIEHFVDIIAGLAILFGATFF--IVAMCI----GYTFLRAMVFFMAIVVAYVPEGLL 348
Query: 448 AALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGL---DLW---GV 501
A +T + +RL + + + + G +++C DKTGTLT++ + LW +
Sbjct: 349 ATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHI 408
Query: 502 VSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDG---------TIQGDPLD--- 549
+ D Q +F W LC + C+ G + GD +
Sbjct: 409 HTADTTEDQSGQTFDQSSE-TWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETAL 467
Query: 550 LKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQ-RM 608
LK E T D F K C + PF+S + ++
Sbjct: 468 LKFSELTLGNAMGYRDRF-----------PKVC---------------EIPFNSTNKFQL 501
Query: 609 TVIVQEMGGD--RLAFMKGAPERVASFCQP---------------ETVPTSFVSELQI-Y 650
++ E D L MKGAPERV C E T+++S +
Sbjct: 502 SIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGE 561
Query: 651 TTQGFRVIALAYKKLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISAR 710
GF + L K + S L F GL+ + + + + + +A
Sbjct: 562 RVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAG 621
Query: 711 IRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYG 770
IR +M+TGD+ TA +A G++SE + +
Sbjct: 622 IRVIMVTGDHPITAKAIAASVGIISEGSETV----------------------------- 652
Query: 771 NQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILIN-GTIFARMSPGQK 829
+D +R V R+ + + G + S L+ + + +FAR SP QK
Sbjct: 653 -EDIAARLRVPVDQVNRKDARACVINGMQLKDMDP--SELVEALRTHPEMVFARTSPQQK 709
Query: 830 SSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISL---SEQEASVASPFTSKTPNIECV 886
+VE Q+L V + GDG ND ALK A +G+++ A A+ N +
Sbjct: 710 LVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASI 769
Query: 887 PHLIKEGRAALVTSFCMFKYMALYSMIQYVGVL---LLYWETN---SLSNYQFLFQDLAI 940
+++GR F K Y++ + + L L+Y + L LF +L
Sbjct: 770 VTGVEQGRLI----FDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCT 825
Query: 941 TTLIGVTMNLNGAYPKLVPFRPAG----RLISPPLLLSVIFNI--LLSLAMHIAGFILVQ 994
V++ A ++ RP RL++ PL F I + S A F +
Sbjct: 826 DIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMA 885
Query: 995 RQPWYSV---------EIHSACTVQNESISELTMSPTAPEKMESNSTFTSFENTTVWFLG 1045
++ W+ + E H +Q+ E T + + TV+F+
Sbjct: 886 QEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTF---------GQRLYQQYTCYTVFFIS 936
Query: 1046 TINCITVALVFSKGK---PFRQPTYTNYIFVLVLIIQLGVCLFILF 1088
C ++ K + F+Q + N I V+ ++ Q+ + F+ +
Sbjct: 937 IEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCY 982
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 111 bits (277), Expect = 5e-24
Identities = 166/782 (21%), Positives = 306/782 (39%), Gaps = 118/782 (15%)
Query: 161 KIHQKFGSGLTREEQEIRRLICGPNTIDVE-VTPIWKLLIKEVLNPFYIFQLFSVCLWF- 218
K GLT + + GPN + TP W +++ F I L F
Sbjct: 52 KYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFL 111
Query: 219 ---------SEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITV--SVCG 267
E + + ++++ + I + +++ K +++S ++ ++
Sbjct: 112 AYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEA-KSSKIMDSFKNMVPQQALVI 170
Query: 268 RKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEG-SCVVDEGMLTGESIPVTKTPLP 326
R+ ++ + +V GDL+ + G +P D +I C VD LTGES P T++P
Sbjct: 171 REGEKMQINAEEVVVGDLVEVKGGD-RVPADLRIISSHGCKVDNSSLTGESEPQTRSP-- 227
Query: 327 KMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILY 386
+ P +T R++ F T ++ GT R +V+ TG T G +
Sbjct: 228 EFTHENPLET-------RNICFFSTNCVE------GTARGIVIATGDRTVMGRIATLASG 274
Query: 387 PKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPAL 446
+ + + F+ + G A + + ++ G E V + +I VP L
Sbjct: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGL 334
Query: 447 PAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGL---DLW---G 500
A +T + +R+ ++ + + + G + +C DKTGTLT++ + +W
Sbjct: 335 LATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQ 394
Query: 501 VVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTWEM 560
+ D Q +F ++ W L C+ + G ++ + + T
Sbjct: 395 IHEADTTEDQSGATF-DKRSPTWTALSRIAGLCNRAVFKAG-----QENISVSKRDT--A 446
Query: 561 AFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVI--VQEMGGD 618
+ + +K + V+ R + E PF+S + I ++
Sbjct: 447 GDASESALLKCIELSCGSVRKMRDRNPKVAE-------IPFNSTNKYQLSIHEREDSPQS 499
Query: 619 RLAFMKGAPERVASFC-----QPETVP------TSFVSELQIYTTQGFRVIALAYKKLEN 667
+ MKGAPER+ C Q + +P +F + G RV+ L +
Sbjct: 500 HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPS 559
Query: 668 DHHATTLTRETVE-----SDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQ 722
+T E L F+GL+ + + + + + SA I+ +M+TGD+
Sbjct: 560 GKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI 619
Query: 723 TAITVARKSGMVSESQKVILIEANETTGSSSASISWTLV-----EEKKHIMYGNQDNYIN 777
TA +A+ G++S E NET +A ++ + E K +++G+ +
Sbjct: 620 TAKAIAKGVGIIS--------EGNETVEDIAARLNIPMSQVNPREAKACVVHGS-----D 666
Query: 778 IRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGT--IFARMSPGQKSSLVEE 835
++D S++ L +IL N T +FAR SP QK +VE
Sbjct: 667 LKDMTSEQ-------------------------LDEILKNHTEIVFARTSPQQKLIIVEG 701
Query: 836 FQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASV---ASPFTSKTPNIECVPHLIKE 892
Q+ V + GDG ND ALK A +GI++ + V A+ N + ++E
Sbjct: 702 CQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEE 761
Query: 893 GR 894
GR
Sbjct: 762 GR 763
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 106 bits (265), Expect = 1e-22
Identities = 198/895 (22%), Positives = 331/895 (36%), Gaps = 150/895 (16%)
Query: 183 GPNTIDVEV-TPIWKLLIKE----VLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISI 237
GPN + E +W+L++++ ++ + L S L + E+ +E A + +I +
Sbjct: 37 GPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIML 96
Query: 238 SLT------VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLL-ILTG 290
L V+ R + L E + + + GVQ + +R +VPGD++ + G
Sbjct: 97 ILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVG 156
Query: 291 NKVLMPCDAVLIEGSCV---VDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVL 347
+KV P D LIE VD+ +LTGES+ VTK ++P D K+++L
Sbjct: 157 DKV--PADLRLIEIKSTTLRVDQSILTGESVSVTKHT-----EAIPDPRAVNQD-KKNML 208
Query: 348 FCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVG 407
F GT + KA V + TG +T G + + +P L R F L
Sbjct: 209 FSGTNITSGKAV------GVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSH 262
Query: 408 TATIGMIYTLCVYVLSGEPPEE----------VVRKALDVITIAVPPALPAALTTGIIYA 457
++ + + + P + A+ + A+P LPA +TT +
Sbjct: 263 AISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALG 322
Query: 458 QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDL--WGVVSCDRNGFQEVHSF 515
RR+ ++ S + G +++C DKTGTLT + + + VV+ G +H F
Sbjct: 323 TRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEF 382
Query: 516 A-SGQA-LPWGPL--------CAAMASCHSLILLDGTIQGDPLDL--------KMFEATT 557
SG P G + C L + LD K+ EAT
Sbjct: 383 TISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATE 442
Query: 558 WEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAILHQFPFSSALQRMTVIV---- 612
+ + ++ A+ V+ + V + + FS + M+V
Sbjct: 443 TALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTR 502
Query: 613 -QEMGGDRLAFMKGAPERVASFCQ-----PETVPTSFVSELQIYT--------TQGFRVI 658
G F+KGAPE V C T P + S QI + R +
Sbjct: 503 PHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCL 562
Query: 659 ALAYK-------KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARI 711
ALA + +E D + + ET DL F+G + + + + E + A I
Sbjct: 563 ALATRDAPPRKEDMELDDCSKFVQYET---DLTFVGCVGMLDPPRPEVAACITRCYQAGI 619
Query: 712 RTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGN 771
R VMITGDN TA+ + R+ G+ +++ V TG
Sbjct: 620 RVVMITGDNKGTAVAICRRLGIFGDTEDV---AGKAYTGR-------------------- 656
Query: 772 QDNYINIRDEVSDKGREGSYHFALTGKSF-HVISQHFSSLLPKILINGTIFARMSPGQKS 830
E D E T + F V H S ++ +
Sbjct: 657 ---------EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL---------------- 691
Query: 831 SLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASVASPFTSKTPNIECVPH 888
+ F ++ G DG ND ALK A +GI++ A A+ N +
Sbjct: 692 ---QSFNEITAMTG---DGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVA 745
Query: 889 LIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSNYQFLFQDLAITTLIGV 946
++EGRA +Y+ ++ + V + L + +L Q L+ +L L
Sbjct: 746 AVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPAT 805
Query: 947 TMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSV 1001
+ N P L R L+ +F L++ +++ G V W+ V
Sbjct: 806 ALGFNP--PDLDIMEKLPRSPREALISGWLFFRYLAIGVYV-GLATVAAATWWFV 857
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 106 bits (265), Expect = 1e-22
Identities = 198/895 (22%), Positives = 331/895 (36%), Gaps = 150/895 (16%)
Query: 183 GPNTIDVEV-TPIWKLLIKE----VLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISI 237
GPN + E +W+L++++ ++ + L S L + E+ +E A + +I +
Sbjct: 37 GPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIML 96
Query: 238 SLT------VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLL-ILTG 290
L V+ R + L E + + + GVQ + +R +VPGD++ + G
Sbjct: 97 ILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVG 156
Query: 291 NKVLMPCDAVLIEGSCV---VDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVL 347
+KV P D LIE VD+ +LTGES+ VTK ++P D K+++L
Sbjct: 157 DKV--PADLRLIEIKSTTLRVDQSILTGESVSVTKHT-----EAIPDPRAVNQD-KKNML 208
Query: 348 FCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVG 407
F GT + KA V + TG +T G + + +P L R F L
Sbjct: 209 FSGTNITSGKAV------GVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSH 262
Query: 408 TATIGMIYTLCVYVLSGEPPEE----------VVRKALDVITIAVPPALPAALTTGIIYA 457
++ + + + P + A+ + A+P LPA +TT +
Sbjct: 263 AISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALG 322
Query: 458 QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDL--WGVVSCDRNGFQEVHSF 515
RR+ ++ S + G +++C DKTGTLT + + + VV+ G +H F
Sbjct: 323 TRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEF 382
Query: 516 A-SGQA-LPWGPL--------CAAMASCHSLILLDGTIQGDPLDL--------KMFEATT 557
SG P G + C L + LD K+ EAT
Sbjct: 383 TISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATE 442
Query: 558 WEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAILHQFPFSSALQRMTVIV---- 612
+ + ++ A+ V+ + V + + FS + M+V
Sbjct: 443 TALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTR 502
Query: 613 -QEMGGDRLAFMKGAPERVASFCQ-----PETVPTSFVSELQIYT--------TQGFRVI 658
G F+KGAPE V C T P + S QI + R +
Sbjct: 503 PHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCL 562
Query: 659 ALAYK-------KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARI 711
ALA + +E D + + ET DL F+G + + + + E + A I
Sbjct: 563 ALATRDAPPRKEDMELDDCSKFVQYET---DLTFVGCVGMLDPPRPEVAACITRCYQAGI 619
Query: 712 RTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGN 771
R VMITGDN TA+ + R+ G+ +++ V TG
Sbjct: 620 RVVMITGDNKGTAVAICRRLGIFGDTEDV---AGKAYTGR-------------------- 656
Query: 772 QDNYINIRDEVSDKGREGSYHFALTGKSF-HVISQHFSSLLPKILINGTIFARMSPGQKS 830
E D E T + F V H S ++ +
Sbjct: 657 ---------EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL---------------- 691
Query: 831 SLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASVASPFTSKTPNIECVPH 888
+ F ++ G DG ND ALK A +GI++ A A+ N +
Sbjct: 692 ---QSFNEITAMTG---DGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVA 745
Query: 889 LIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSNYQFLFQDLAITTLIGV 946
++EGRA +Y+ ++ + V + L + +L Q L+ +L L
Sbjct: 746 AVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPAT 805
Query: 947 TMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSV 1001
+ N P L R L+ +F L++ +++ G V W+ V
Sbjct: 806 ALGFNP--PDLDIMEKLPRSPREALISGWLFFRYLAIGVYV-GLATVAAATWWFV 857
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 106 bits (265), Expect = 1e-22
Identities = 198/895 (22%), Positives = 331/895 (36%), Gaps = 150/895 (16%)
Query: 183 GPNTIDVEV-TPIWKLLIKE----VLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISI 237
GPN + E +W+L++++ ++ + L S L + E+ +E A + +I +
Sbjct: 37 GPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIML 96
Query: 238 SLT------VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLL-ILTG 290
L V+ R + L E + + + GVQ + +R +VPGD++ + G
Sbjct: 97 ILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVG 156
Query: 291 NKVLMPCDAVLIEGSCV---VDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVL 347
+KV P D LIE VD+ +LTGES+ VTK ++P D K+++L
Sbjct: 157 DKV--PADLRLIEIKSTTLRVDQSILTGESVSVTKHT-----EAIPDPRAVNQD-KKNML 208
Query: 348 FCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVG 407
F GT + KA V + TG +T G + + +P L R F L
Sbjct: 209 FSGTNITSGKAV------GVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSH 262
Query: 408 TATIGMIYTLCVYVLSGEPPEE----------VVRKALDVITIAVPPALPAALTTGIIYA 457
++ + + + P + A+ + A+P LPA +TT +
Sbjct: 263 AISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALG 322
Query: 458 QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDL--WGVVSCDRNGFQEVHSF 515
RR+ ++ S + G +++C DKTGTLT + + + VV+ G +H F
Sbjct: 323 TRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEF 382
Query: 516 A-SGQA-LPWGPL--------CAAMASCHSLILLDGTIQGDPLDL--------KMFEATT 557
SG P G + C L + LD K+ EAT
Sbjct: 383 TISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATE 442
Query: 558 WEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAILHQFPFSSALQRMTVIV---- 612
+ + ++ A+ V+ + V + + FS + M+V
Sbjct: 443 TALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTR 502
Query: 613 -QEMGGDRLAFMKGAPERVASFCQ-----PETVPTSFVSELQIYT--------TQGFRVI 658
G F+KGAPE V C T P + S QI + R +
Sbjct: 503 PHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCL 562
Query: 659 ALAYK-------KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARI 711
ALA + +E D + + ET DL F+G + + + + E + A I
Sbjct: 563 ALATRDAPPRKEDMELDDCSKFVQYET---DLTFVGCVGMLDPPRPEVAACITRCYQAGI 619
Query: 712 RTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGN 771
R VMITGDN TA+ + R+ G+ +++ V TG
Sbjct: 620 RVVMITGDNKGTAVAICRRLGIFGDTEDV---AGKAYTGR-------------------- 656
Query: 772 QDNYINIRDEVSDKGREGSYHFALTGKSF-HVISQHFSSLLPKILINGTIFARMSPGQKS 830
E D E T + F V H S ++ +
Sbjct: 657 ---------EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL---------------- 691
Query: 831 SLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASVASPFTSKTPNIECVPH 888
+ F ++ G DG ND ALK A +GI++ A A+ N +
Sbjct: 692 ---QSFNEITAMTG---DGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVA 745
Query: 889 LIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSNYQFLFQDLAITTLIGV 946
++EGRA +Y+ ++ + V + L + +L Q L+ +L L
Sbjct: 746 AVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPAT 805
Query: 947 TMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSV 1001
+ N P L R L+ +F L++ +++ G V W+ V
Sbjct: 806 ALGFNP--PDLDIMEKLPRSPREALISGWLFFRYLAIGVYV-GLATVAAATWWFV 857
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 106 bits (265), Expect = 1e-22
Identities = 198/895 (22%), Positives = 331/895 (36%), Gaps = 150/895 (16%)
Query: 183 GPNTIDVEV-TPIWKLLIKE----VLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISI 237
GPN + E +W+L++++ ++ + L S L + E+ +E A + +I +
Sbjct: 37 GPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIML 96
Query: 238 SLT------VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLL-ILTG 290
L V+ R + L E + + + GVQ + +R +VPGD++ + G
Sbjct: 97 ILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVG 156
Query: 291 NKVLMPCDAVLIEGSCV---VDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVL 347
+KV P D LIE VD+ +LTGES+ VTK ++P D K+++L
Sbjct: 157 DKV--PADLRLIEIKSTTLRVDQSILTGESVSVTKHT-----EAIPDPRAVNQD-KKNML 208
Query: 348 FCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVG 407
F GT + KA V + TG +T G + + +P L R F L
Sbjct: 209 FSGTNITSGKAV------GVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSH 262
Query: 408 TATIGMIYTLCVYVLSGEPPEE----------VVRKALDVITIAVPPALPAALTTGIIYA 457
++ + + + P + A+ + A+P LPA +TT +
Sbjct: 263 AISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALG 322
Query: 458 QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDL--WGVVSCDRNGFQEVHSF 515
RR+ ++ S + G +++C DKTGTLT + + + VV+ G +H F
Sbjct: 323 TRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEF 382
Query: 516 A-SGQA-LPWGPL--------CAAMASCHSLILLDGTIQGDPLDL--------KMFEATT 557
SG P G + C L + LD K+ EAT
Sbjct: 383 TISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATE 442
Query: 558 WEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAILHQFPFSSALQRMTVIV---- 612
+ + ++ A+ V+ + V + + FS + M+V
Sbjct: 443 TALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTR 502
Query: 613 -QEMGGDRLAFMKGAPERVASFCQ-----PETVPTSFVSELQIYT--------TQGFRVI 658
G F+KGAPE V C T P + S QI + R +
Sbjct: 503 PHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCL 562
Query: 659 ALAYK-------KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARI 711
ALA + +E D + + ET DL F+G + + + + E + A I
Sbjct: 563 ALATRDAPPRKEDMELDDCSKFVQYET---DLTFVGCVGMLDPPRPEVAACITRCYQAGI 619
Query: 712 RTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGN 771
R VMITGDN TA+ + R+ G+ +++ V TG
Sbjct: 620 RVVMITGDNKGTAVAICRRLGIFGDTEDV---AGKAYTGR-------------------- 656
Query: 772 QDNYINIRDEVSDKGREGSYHFALTGKSF-HVISQHFSSLLPKILINGTIFARMSPGQKS 830
E D E T + F V H S ++ +
Sbjct: 657 ---------EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL---------------- 691
Query: 831 SLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASVASPFTSKTPNIECVPH 888
+ F ++ G DG ND ALK A +GI++ A A+ N +
Sbjct: 692 ---QSFNEITAMTG---DGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVA 745
Query: 889 LIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSNYQFLFQDLAITTLIGV 946
++EGRA +Y+ ++ + V + L + +L Q L+ +L L
Sbjct: 746 AVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPAT 805
Query: 947 TMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSV 1001
+ N P L R L+ +F L++ +++ G V W+ V
Sbjct: 806 ALGFNP--PDLDIMEKLPRSPREALISGWLFFRYLAIGVYV-GLATVAAATWWFV 857
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 106 bits (265), Expect = 1e-22
Identities = 198/895 (22%), Positives = 331/895 (36%), Gaps = 150/895 (16%)
Query: 183 GPNTIDVEV-TPIWKLLIKE----VLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISI 237
GPN + E +W+L++++ ++ + L S L + E+ +E A + +I +
Sbjct: 37 GPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIML 96
Query: 238 SLT------VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLL-ILTG 290
L V+ R + L E + + + GVQ + +R +VPGD++ + G
Sbjct: 97 ILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVG 156
Query: 291 NKVLMPCDAVLIEGSCV---VDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVL 347
+KV P D LIE VD+ +LTGES+ VTK ++P D K+++L
Sbjct: 157 DKV--PADLRLIEIKSTTLRVDQSILTGESVSVTKHT-----EAIPDPRAVNQD-KKNML 208
Query: 348 FCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVG 407
F GT + KA V + TG +T G + + +P L R F L
Sbjct: 209 FSGTNITSGKAV------GVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSH 262
Query: 408 TATIGMIYTLCVYVLSGEPPEE----------VVRKALDVITIAVPPALPAALTTGIIYA 457
++ + + + P + A+ + A+P LPA +TT +
Sbjct: 263 AISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALG 322
Query: 458 QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDL--WGVVSCDRNGFQEVHSF 515
RR+ ++ S + G +++C DKTGTLT + + + VV+ G +H F
Sbjct: 323 TRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEF 382
Query: 516 A-SGQA-LPWGPL--------CAAMASCHSLILLDGTIQGDPLDL--------KMFEATT 557
SG P G + C L + LD K+ EAT
Sbjct: 383 TISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATE 442
Query: 558 WEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAILHQFPFSSALQRMTVIV---- 612
+ + ++ A+ V+ + V + + FS + M+V
Sbjct: 443 TALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTR 502
Query: 613 -QEMGGDRLAFMKGAPERVASFCQ-----PETVPTSFVSELQIYT--------TQGFRVI 658
G F+KGAPE V C T P + S QI + R +
Sbjct: 503 PHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCL 562
Query: 659 ALAYK-------KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARI 711
ALA + +E D + + ET DL F+G + + + + E + A I
Sbjct: 563 ALATRDAPPRKEDMELDDCSKFVQYET---DLTFVGCVGMLDPPRPEVAACITRCYQAGI 619
Query: 712 RTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGN 771
R VMITGDN TA+ + R+ G+ +++ V TG
Sbjct: 620 RVVMITGDNKGTAVAICRRLGIFGDTEDV---AGKAYTGR-------------------- 656
Query: 772 QDNYINIRDEVSDKGREGSYHFALTGKSF-HVISQHFSSLLPKILINGTIFARMSPGQKS 830
E D E T + F V H S ++ +
Sbjct: 657 ---------EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL---------------- 691
Query: 831 SLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASVASPFTSKTPNIECVPH 888
+ F ++ G DG ND ALK A +GI++ A A+ N +
Sbjct: 692 ---QSFNEITAMTG---DGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVA 745
Query: 889 LIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSNYQFLFQDLAITTLIGV 946
++EGRA +Y+ ++ + V + L + +L Q L+ +L L
Sbjct: 746 AVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPAT 805
Query: 947 TMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSV 1001
+ N P L R L+ +F L++ +++ G V W+ V
Sbjct: 806 ALGFNP--PDLDIMEKLPRSPREALISGWLFFRYLAIGVYV-GLATVAAATWWFV 857
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 106 bits (265), Expect = 1e-22
Identities = 198/895 (22%), Positives = 331/895 (36%), Gaps = 150/895 (16%)
Query: 183 GPNTIDVEV-TPIWKLLIKE----VLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISI 237
GPN + E +W+L++++ ++ + L S L + E+ +E A + +I +
Sbjct: 37 GPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIML 96
Query: 238 SLT------VYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLL-ILTG 290
L V+ R + L E + + + GVQ + +R +VPGD++ + G
Sbjct: 97 ILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVG 156
Query: 291 NKVLMPCDAVLIEGSCV---VDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVL 347
+KV P D LIE VD+ +LTGES+ VTK ++P D K+++L
Sbjct: 157 DKV--PADLRLIEIKSTTLRVDQSILTGESVSVTKHT-----EAIPDPRAVNQD-KKNML 208
Query: 348 FCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVG 407
F GT + KA V + TG +T G + + +P L R F L
Sbjct: 209 FSGTNITSGKAV------GVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSH 262
Query: 408 TATIGMIYTLCVYVLSGEPPEE----------VVRKALDVITIAVPPALPAALTTGIIYA 457
++ + + + P + A+ + A+P LPA +TT +
Sbjct: 263 AISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALG 322
Query: 458 QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDL--WGVVSCDRNGFQEVHSF 515
RR+ ++ S + G +++C DKTGTLT + + + VV+ G +H F
Sbjct: 323 TRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEF 382
Query: 516 A-SGQA-LPWGPL--------CAAMASCHSLILLDGTIQGDPLDL--------KMFEATT 557
SG P G + C L + LD K+ EAT
Sbjct: 383 TISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATE 442
Query: 558 WEMAFSGDDFHIKGVPAHAMV-VKPCRTASQVPVEGIAILHQFPFSSALQRMTVIV---- 612
+ + ++ A+ V+ + V + + FS + M+V
Sbjct: 443 TALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTR 502
Query: 613 -QEMGGDRLAFMKGAPERVASFCQ-----PETVPTSFVSELQIYT--------TQGFRVI 658
G F+KGAPE V C T P + S QI + R +
Sbjct: 503 PHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCL 562
Query: 659 ALAYK-------KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARI 711
ALA + +E D + + ET DL F+G + + + + E + A I
Sbjct: 563 ALATRDAPPRKEDMELDDCSKFVQYET---DLTFVGCVGMLDPPRPEVAACITRCYQAGI 619
Query: 712 RTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGN 771
R VMITGDN TA+ + R+ G+ +++ V TG
Sbjct: 620 RVVMITGDNKGTAVAICRRLGIFGDTEDV---AGKAYTGR-------------------- 656
Query: 772 QDNYINIRDEVSDKGREGSYHFALTGKSF-HVISQHFSSLLPKILINGTIFARMSPGQKS 830
E D E T + F V H S ++ +
Sbjct: 657 ---------EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL---------------- 691
Query: 831 SLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSE--QEASVASPFTSKTPNIECVPH 888
+ F ++ G DG ND ALK A +GI++ A A+ N +
Sbjct: 692 ---QSFNEITAMTG---DGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVA 745
Query: 889 LIKEGRAALVTSFCMFKYMALYSMIQYVGVLL--LYWETNSLSNYQFLFQDLAITTLIGV 946
++EGRA +Y+ ++ + V + L + +L Q L+ +L L
Sbjct: 746 AVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPAT 805
Query: 947 TMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSV 1001
+ N P L R L+ +F L++ +++ G V W+ V
Sbjct: 806 ALGFNP--PDLDIMEKLPRSPREALISGWLFFRYLAIGVYV-GLATVAAATWWFV 857
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,891,583
Number of Sequences: 37866
Number of extensions: 1875743
Number of successful extensions: 4345
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3985
Number of HSP's gapped (non-prelim): 183
length of query: 1196
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1082
effective length of database: 13,930,794
effective search space: 15073119108
effective search space used: 15073119108
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.