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Search of human proteins with 66879666
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66879666 Fanconi anemia, complementation group A isoform b
[Homo sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66879666 Fanconi anemia, complementation group A isoform b [H... 587 e-168
gi|66880553 Fanconi anemia, complementation group A isoform a [H... 587 e-168
gi|28173564 keratin 73 [Homo sapiens] 31 1.5
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 30 2.6
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 30 2.6
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 30 2.6
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 30 3.3
gi|221139830 transmembrane protein 25 isoform 2 [Homo sapiens] 29 4.4
gi|221219039 transmembrane protein 25 isoform 2 [Homo sapiens] 29 4.4
gi|221139840 transmembrane protein 25 isoform 5 [Homo sapiens] 29 4.4
gi|126012573 low density lipoprotein-related protein 2 [Homo sap... 29 4.4
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 29 4.4
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 29 5.7
gi|223278356 glutamate receptor, ionotropic, N-methyl-D-aspartat... 28 9.7
gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Hom... 28 9.7
gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Hom... 28 9.7
gi|172073175 microtubule associated serine/threonine kinase-like... 28 9.7
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 28 9.7
gi|118498337 HECT domain containing 1 [Homo sapiens] 28 9.7
gi|34485727 NCK-associated protein 1-like [Homo sapiens] 28 9.7
>gi|66879666 Fanconi anemia, complementation group A isoform b [Homo
sapiens]
Length = 297
Score = 587 bits (1514), Expect = e-168
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL 60
MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
Sbjct: 1 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL 60
Query: 61 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS 120
LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
Sbjct: 61 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS 120
Query: 121 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE 180
VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
Sbjct: 121 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE 180
Query: 181 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ 240
AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
Sbjct: 181 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ 240
Query: 241 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRC 297
MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRC
Sbjct: 241 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRC 297
>gi|66880553 Fanconi anemia, complementation group A isoform a [Homo
sapiens]
Length = 1455
Score = 587 bits (1514), Expect = e-168
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL 60
MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
Sbjct: 1 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL 60
Query: 61 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS 120
LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
Sbjct: 61 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS 120
Query: 121 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE 180
VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
Sbjct: 121 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE 180
Query: 181 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ 240
AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
Sbjct: 181 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ 240
Query: 241 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRC 297
MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRC
Sbjct: 241 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRC 297
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 30.8 bits (68), Expect = 1.5
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 41 QKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANH-SSSFIGSALQ 99
Q+ KE R+LR +Q+L ++ L ++ + L + +C S Y N S S I S++
Sbjct: 404 QQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMA 463
Query: 100 DQASRLGVPVGILSAG 115
A G G +AG
Sbjct: 464 GMAG-TGAGFGFSNAG 478
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 30.0 bits (66), Expect = 2.6
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 44 KESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQAS 103
KE R+LR +Q+L +L L ++ + L + +C S Y N S + S+ A
Sbjct: 400 KEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAG 459
Query: 104 RLGVPVGILSAGMVASSVGQICTAPAE 130
G S G ASS TA A+
Sbjct: 460 GAG-----FSMGFGASSSYSYKTAAAD 481
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 30.0 bits (66), Expect = 2.6
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 44 KESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQAS 103
KE R+LR +Q+L +L L ++ + L + +C S Y N S + S+ A
Sbjct: 358 KEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAG 417
Query: 104 RLGVPVGILSAGMVASSVGQICTAPAE 130
G S G ASS TA A+
Sbjct: 418 GAG-----FSMGFGASSSYSYKTAAAD 439
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 30.0 bits (66), Expect = 2.6
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 44 KESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQAS 103
KE R+LR +Q+L +L L ++ + L + +C S Y N S + S+ A
Sbjct: 400 KEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAG 459
Query: 104 RLGVPVGILSAGMVASSVGQICTAPAE 130
G S G ASS TA A+
Sbjct: 460 GAG-----FSMGFGASSSYSYKTAAAD 481
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 29.6 bits (65), Expect = 3.3
Identities = 41/138 (29%), Positives = 58/138 (42%), Gaps = 19/138 (13%)
Query: 7 PNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEG 66
P + G PG R++AW L A + + PE K +A L + + L L + EG
Sbjct: 1015 PLAGPGISPGARKQAW--LPADHLSKV---PE-----KLAAAPLSVASKALQKLAAQ-EG 1063
Query: 67 PLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICT 126
P LSLS+ SS + A G L D S L G+ AG + +
Sbjct: 1064 P----LSLSRCSSL-SSLSSAGRPGPSEGGDLDDSDSSL---EGLEEAGPSEAELDSTWR 1115
Query: 127 APAETSHPVLLTVEQRKK 144
AP TS PV + +R +
Sbjct: 1116 APGATSLPVAIPAPRRNR 1133
>gi|221139830 transmembrane protein 25 isoform 2 [Homo sapiens]
Length = 322
Score = 29.3 bits (64), Expect = 4.4
Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 15/137 (10%)
Query: 9 SASGQDPGGRRRAWAELLAG-RVKRE------KYNPERAQKLKESAVRLLRSHQDLNALL 61
+ S QDP R A A ++ + K E KY + L L+R++ N
Sbjct: 106 NCSLQDPRSGRSANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPPANVTW 165
Query: 62 LEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSV 121
++ +GP+ S V+D + NH+ + L+ A L V V G+ ++S+
Sbjct: 166 IDQDGPVTVNTSDFLVLDAQNYPWLTNHT---VQLQLRSLAHNLSV-VATNDVGVTSASL 221
Query: 122 GQICTAPAETSHPVLLT 138
AP + HP L++
Sbjct: 222 ----PAPGPSRHPSLIS 234
>gi|221219039 transmembrane protein 25 isoform 2 [Homo sapiens]
Length = 322
Score = 29.3 bits (64), Expect = 4.4
Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 15/137 (10%)
Query: 9 SASGQDPGGRRRAWAELLAG-RVKRE------KYNPERAQKLKESAVRLLRSHQDLNALL 61
+ S QDP R A A ++ + K E KY + L L+R++ N
Sbjct: 106 NCSLQDPRSGRSANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPPANVTW 165
Query: 62 LEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSV 121
++ +GP+ S V+D + NH+ + L+ A L V V G+ ++S+
Sbjct: 166 IDQDGPVTVNTSDFLVLDAQNYPWLTNHT---VQLQLRSLAHNLSV-VATNDVGVTSASL 221
Query: 122 GQICTAPAETSHPVLLT 138
AP + HP L++
Sbjct: 222 ----PAPGPSRHPSLIS 234
>gi|221139840 transmembrane protein 25 isoform 5 [Homo sapiens]
Length = 306
Score = 29.3 bits (64), Expect = 4.4
Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 15/137 (10%)
Query: 9 SASGQDPGGRRRAWAELLAG-RVKRE------KYNPERAQKLKESAVRLLRSHQDLNALL 61
+ S QDP R A A ++ + K E KY + L L+R++ N
Sbjct: 106 NCSLQDPRSGRSANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPPANVTW 165
Query: 62 LEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSV 121
++ +GP+ S V+D + NH+ + L+ A L V V G+ ++S+
Sbjct: 166 IDQDGPVTVNTSDFLVLDAQNYPWLTNHT---VQLQLRSLAHNLSV-VATNDVGVTSASL 221
Query: 122 GQICTAPAETSHPVLLT 138
AP + HP L++
Sbjct: 222 ----PAPGPSRHPSLIS 234
>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
Length = 4655
Score = 29.3 bits (64), Expect = 4.4
Identities = 17/44 (38%), Positives = 23/44 (52%)
Query: 100 DQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRK 143
DQ + GVP I SA M +SV + T E V L +E++K
Sbjct: 1889 DQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDIEEQK 1932
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 29.3 bits (64), Expect = 4.4
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 18 RRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDL 57
R R A+ L+G+ KR + E A+ L+E A RL R ++L
Sbjct: 297 RLRQEAQALSGQAKRAELYREEAEALRERAGRLPRLQEEL 336
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 28.9 bits (63), Expect = 5.7
Identities = 31/126 (24%), Positives = 53/126 (42%), Gaps = 9/126 (7%)
Query: 24 ELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSS 83
++L R++ E+ + Q+L+E+A L +DL L EVEG C + + D S+
Sbjct: 209 QVLLSRLEEEEQ--DILQRLRENAAHLGDKRRDLAHLAAEVEGK-CLQSGFEMLKDVKST 265
Query: 84 ----EAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTV 139
E + + L+ S P + + + T ET+HP L+
Sbjct: 266 LEKCEKVKTMEVTSVSIELEKNFSNF--PRQYFALRKILKQLIADVTLDPETAHPNLVLS 323
Query: 140 EQRKKL 145
E RK +
Sbjct: 324 EDRKSV 329
>gi|223278356 glutamate receptor, ionotropic, N-methyl-D-aspartate
3A [Homo sapiens]
Length = 1115
Score = 28.1 bits (61), Expect = 9.7
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 128 PAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSF--CQELWKIQSSLLL-EAVWH 184
P E+ +P+ L + LSS + +L + + S CQE W I LLL +
Sbjct: 229 PRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTQNNSK 288
Query: 185 LHVQGIVSLQELLESHPDM 203
H+ I+++ L S D+
Sbjct: 289 FHLGSIINITANLPSTQDL 307
>gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Homo
sapiens]
Length = 1324
Score = 28.1 bits (61), Expect = 9.7
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 187 VQGIVSLQELLESHPDMHAVGSWLFRN-----LCCLCEQMEASCQH 227
VQ + L LL S+P+ H G W F + +CE+M+ + H
Sbjct: 1060 VQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTSGH 1105
>gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Homo
sapiens]
Length = 1463
Score = 28.1 bits (61), Expect = 9.7
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 187 VQGIVSLQELLESHPDMHAVGSWLFRN-----LCCLCEQMEASCQH 227
VQ + L LL S+P+ H G W F + +CE+M+ + H
Sbjct: 1060 VQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTSGH 1105
>gi|172073175 microtubule associated serine/threonine kinase-like
[Homo sapiens]
Length = 878
Score = 28.1 bits (61), Expect = 9.7
Identities = 15/52 (28%), Positives = 28/52 (53%)
Query: 89 HSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVE 140
+SS + S L+ AS G+PV L++ ++ S ++ + SH + +VE
Sbjct: 263 YSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATSSASSQSHTFISSVE 314
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 28.1 bits (61), Expect = 9.7
Identities = 14/52 (26%), Positives = 25/52 (48%)
Query: 66 GPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMV 117
GP CK+ L V DSSE+ + I + ++ A R+ + + G++
Sbjct: 789 GPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGII 840
>gi|118498337 HECT domain containing 1 [Homo sapiens]
Length = 2610
Score = 28.1 bits (61), Expect = 9.7
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 8/58 (13%)
Query: 8 NSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVE 65
+S DPG E GR+K E+ R + L E A +++ H D + +LEVE
Sbjct: 2113 SSVRRDDPG-------EFRVGRLKHERVKVPRGESLMEWAENVMQIHADRKS-VLEVE 2162
>gi|34485727 NCK-associated protein 1-like [Homo sapiens]
Length = 1127
Score = 28.1 bits (61), Expect = 9.7
Identities = 37/151 (24%), Positives = 66/151 (43%), Gaps = 32/151 (21%)
Query: 47 AVRLLRSHQD-----LNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSAL--- 98
A +L H D L ++LE + PL KKL+ E + H+ + G+ L
Sbjct: 161 AHEMLHGHGDPSFARLGQMVLEYDHPL-KKLT----------EEFGPHTKAVSGALLSLH 209
Query: 99 -----QDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQ 153
++Q + +LS ++++ I A ++T L+VE ++ +
Sbjct: 210 FLFVRRNQGAEQWRSAQLLS--LISNPPAMINPANSDTMACEYLSVEVMERWIII----G 263
Query: 154 YLLAHSMFSRLSFCQELWK--IQSSLLLEAV 182
+LL H + S CQ+LWK +Q SL + +
Sbjct: 264 FLLCHGCLNSNSQCQKLWKLCLQGSLYITLI 294
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.131 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,526,741
Number of Sequences: 37866
Number of extensions: 413888
Number of successful extensions: 1296
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1283
Number of HSP's gapped (non-prelim): 22
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.