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Search of human proteins with 63252913
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252913 gelsolin-like capping protein [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252913 gelsolin-like capping protein [Homo sapiens] 708 0.0
gi|162951877 scinderin isoform 1 [Homo sapiens] 352 4e-97
gi|4504165 gelsolin isoform a precursor [Homo sapiens] 342 2e-94
gi|38044288 gelsolin isoform b [Homo sapiens] 342 2e-94
gi|189083782 gelsolin isoform c [Homo sapiens] 342 2e-94
gi|189083780 gelsolin isoform c [Homo sapiens] 342 2e-94
gi|189083778 gelsolin isoform b [Homo sapiens] 342 2e-94
gi|189083776 gelsolin isoform b [Homo sapiens] 342 2e-94
gi|189083774 gelsolin isoform b [Homo sapiens] 342 2e-94
gi|189083772 gelsolin isoform b [Homo sapiens] 342 2e-94
gi|194394237 villin 1 [Homo sapiens] 259 2e-69
gi|17572824 advillin [Homo sapiens] 257 1e-68
gi|94721268 villin-like protein [Homo sapiens] 211 1e-54
gi|4503743 flightless I homolog [Homo sapiens] 148 6e-36
gi|14916473 scinderin isoform 2 [Homo sapiens] 129 3e-30
gi|150417973 supervillin isoform 2 [Homo sapiens] 62 1e-09
gi|150417971 supervillin isoform 1 [Homo sapiens] 62 1e-09
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 33 0.38
gi|239750652 PREDICTED: hypothetical protein XP_002347499 [Homo ... 30 2.5
gi|239744960 PREDICTED: hypothetical protein XP_002343317 [Homo ... 30 2.5
gi|154744870 zinc finger protein 574 [Homo sapiens] 30 4.2
gi|34485720 echinoderm microtubule associated protein like 5 [Ho... 29 5.5
gi|16904383 leucine rich repeat containing 7 [Homo sapiens] 29 7.1
gi|51317380 D-glucuronyl C5-epimerase [Homo sapiens] 29 7.1
gi|32129212 zinc finger protein 434 [Homo sapiens] 28 9.3
>gi|63252913 gelsolin-like capping protein [Homo sapiens]
Length = 348
Score = 708 bits (1828), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSH 60
MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSH
Sbjct: 1 MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSH 60
Query: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
Sbjct: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLT 240
KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLT
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLT 240
Query: 241 ADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRK 300
ADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRK
Sbjct: 241 ADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRK 300
Query: 301 ANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
ANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK
Sbjct: 301 ANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
>gi|162951877 scinderin isoform 1 [Homo sapiens]
Length = 715
Score = 352 bits (902), Expect = 4e-97
Identities = 166/340 (48%), Positives = 240/340 (70%), Gaps = 4/340 (1%)
Query: 12 FPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHLHLWIGQQ 68
F + + GL VWR+EKL+ VPV Q G F+ GD+YLVLH HLH W+G++
Sbjct: 10 FARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKE 69
Query: 69 SSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKT 128
S+DE A A+ V ++ LG +PVQ+RE+QG ES+ F+SYF GLKY+ GGV S +
Sbjct: 70 CSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHV 129
Query: 129 STGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERN 188
T A K+L VKG++ +RATE L+WDSFN GDCFI+DLG I+ WCG N ER
Sbjct: 130 LTNDLTA-KRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERL 188
Query: 189 KARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQA 248
KA +A IR +ER+G++++ +V +G EP+E+I+VLG KP L +G ++D+ AD +N +
Sbjct: 189 KANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISNRKM 248
Query: 249 AALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQA 308
A LY VSDA+G M +T VA+ +PF++ +L+S++CF+LD+G +I++WKG+ AN +ER+A
Sbjct: 249 AKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKA 308
Query: 309 ALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A++ AE F+ +M Y+ NTQ+++LP+G E+PIFKQFFKDW+
Sbjct: 309 AMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWR 348
Score = 118 bits (295), Expect = 9e-27
Identities = 99/335 (29%), Positives = 155/335 (46%), Gaps = 30/335 (8%)
Query: 21 LHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVL 80
+ +WRVE + V Q + G F+ GD Y++L+ P ++ W G ++RDE A L
Sbjct: 398 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTTSAFL 456
Query: 81 AVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKKL 139
V L+ LG + VQ R QG E +S F + L + G K APA +L
Sbjct: 457 TVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTS----KKGGQAPAPPTRL 512
Query: 140 YQVKGKKNIRATERALNWD----SFNTGDCFILDLGQNI-FAWCGGKSNILERNKARDLA 194
+QV ++N+ + R + D S N+ D F+L L QN + W G ++ E A +A
Sbjct: 513 FQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 570
Query: 195 LAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKV 254
+ K + + +GEEP E LG K+ L +A LY
Sbjct: 571 SVL-------KCKTLRIQEGEEPEEFWNSLGG----KKDYQTSPLLETQAEDHPPRLYGC 619
Query: 255 SDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAE 314
S+ TG+ + ++ F + L DD +LD +I+IW G+ ANE E++ +L+ A+
Sbjct: 620 SNKTGRFVIEEI--PGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAK 675
Query: 315 GFISRMQYA--PNTQVEILPQGHESPIFKQFFKDW 347
++ T + I+ QGHE P F +F W
Sbjct: 676 MYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
>gi|4504165 gelsolin isoform a precursor [Homo sapiens]
Length = 782
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 64 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 122
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 123 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 181
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 182 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 241
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 242 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 300
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 301 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 360
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 361 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 397
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 449 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 508
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 509 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 564
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 565 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 624
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 625 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 674
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 675 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 730
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 731 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 763
>gi|38044288 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 13 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 72 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 130
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 131 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 190
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 191 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 249
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 250 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 309
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 310 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 346
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 398 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 458 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 513
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 514 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 573
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 574 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 623
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 624 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 679
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 680 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 712
>gi|189083782 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 24 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 82
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 83 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 141
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 142 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 201
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 202 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 260
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 261 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 320
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 321 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 357
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 409 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 468
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 469 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 524
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 525 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 584
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 585 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 634
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 635 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 690
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 691 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 723
>gi|189083780 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 24 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 82
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 83 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 141
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 142 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 201
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 202 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 260
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 261 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 320
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 321 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 357
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 409 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 468
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 469 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 524
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 525 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 584
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 585 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 634
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 635 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 690
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 691 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 723
>gi|189083778 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 13 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 72 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 130
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 131 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 190
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 191 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 249
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 250 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 309
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 310 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 346
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 398 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 458 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 513
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 514 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 573
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 574 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 623
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 624 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 679
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 680 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 712
>gi|189083776 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 13 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 72 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 130
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 131 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 190
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 191 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 249
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 250 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 309
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 310 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 346
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 398 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 458 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 513
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 514 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 573
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 574 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 623
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 624 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 679
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 680 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 712
>gi|189083774 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 13 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 72 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 130
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 131 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 190
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 191 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 249
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 250 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 309
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 310 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 346
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 398 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 458 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 513
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 514 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 573
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 574 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 623
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 624 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 679
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 680 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 712
>gi|189083772 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 342 bits (878), Expect = 2e-94
Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71
++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+
Sbjct: 13 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K
Sbjct: 72 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 130
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA
Sbjct: 131 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 190
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251
++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L
Sbjct: 191 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 249
Query: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311
YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+
Sbjct: 250 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 309
Query: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A FI++M Y TQV +LP+G E+P+FKQFFK+W+
Sbjct: 310 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 346
Score = 125 bits (314), Expect = 6e-29
Identities = 99/333 (29%), Positives = 156/333 (46%), Gaps = 26/333 (7%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79
+WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+
Sbjct: 398 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457
Query: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKK 138
L L+ LG PVQ R VQG E MS F + + +GG +T APA+ +
Sbjct: 458 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQT---APAS-TR 513
Query: 139 LYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALA 196
L+QV+ RA E + N+ D F+L + W G ++ E+ A++L
Sbjct: 514 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 573
Query: 197 IRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSD 256
+R AQ V +G EP + LG K A + +D K +A L+ S+
Sbjct: 574 LR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRLFACSN 623
Query: 257 ATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGF 316
G+ + +V E L +DD +LD ++++W G+ + E+E+ AL A+ +
Sbjct: 624 KIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRY 679
Query: 317 ISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347
I T + ++ QG E P F +F W
Sbjct: 680 IETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 712
>gi|194394237 villin 1 [Homo sapiens]
Length = 827
Score = 259 bits (663), Expect = 2e-69
Identities = 146/342 (42%), Positives = 201/342 (58%), Gaps = 14/342 (4%)
Query: 15 SVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL--HNGPEEVSH-LHLWIGQQSSR 71
++ PGL +WR+E ++ VPV G FF GD Y++L H +S+ +H WIGQ SS
Sbjct: 13 NITTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSL 72
Query: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131
DEQGA A+ ++ L R VQHREVQGNES+ F YF +GL ++GGV S T
Sbjct: 73 DEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETN 132
Query: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191
+ +++L VKGK+N+ A E ++W SFN GD F+LDLG+ I W G +S +ER +
Sbjct: 133 S-YDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGM 191
Query: 192 DLALAIRDSERQGKAQVEIVTDGEEPAE------MIQVLGPKPALKEGNPEEDLTADKAN 245
LA IRD ER G+ V +V E A M VLG + LK P D + A
Sbjct: 192 TLAKEIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVP--DTVVEPAL 249
Query: 246 AQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKE 305
A LY VSD+ G + + +VA + P +LL +DC++LD G KIY+WKG+KANE+E
Sbjct: 250 KAALKLYHVSDSEGNLVVREVA-TRPLTQDLLSHEDCYILDQGGL-KIYVWKGKKANEQE 307
Query: 306 RQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDW 347
++ A+ A FI QY P+TQVE+ G ES +F+Q F+ W
Sbjct: 308 KKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 139 bits (351), Expect = 3e-33
Identities = 107/336 (31%), Positives = 165/336 (49%), Gaps = 30/336 (8%)
Query: 21 LHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGAC 77
+ VWR+E L+ VPV + G F+ GD YL+L+ G ++ L++W G Q+S+DE A
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459
Query: 78 AVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIK 137
A AV L+ PVQ R G E MS F + +GG S + TG
Sbjct: 460 AYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGT-SRTNNLETGPST--- 515
Query: 138 KLYQVK--GKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLAL 195
+L+QV+ G N +A E + N+ D F+L + WCG + ER A+ +A
Sbjct: 516 RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVAD 575
Query: 196 AIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKP--ALKEGNPEEDLTADKANAQAAALYK 253
I +E+Q +V +G+EPA LG K A + EE+L L++
Sbjct: 576 TISRTEKQ------VVVEGQEPANFWMALGGKAPYANTKRLQEENLVI------TPRLFE 623
Query: 254 VSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVA 313
S+ TG+ T++ D + LE DD F+LD + +++ W G+ ANE+E++AA A
Sbjct: 624 CSNKTGRFLATEIPDFNQDDLE---EDDVFLLD--VWDQVFFWIGKHANEEEKKAAATTA 678
Query: 314 EGFISRMQYA--PNTQVEILPQGHESPIFKQFFKDW 347
+ ++ P T + ++ QGHE P F +F W
Sbjct: 679 QEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAW 714
>gi|17572824 advillin [Homo sapiens]
Length = 819
Score = 257 bits (656), Expect = 1e-68
Identities = 149/349 (42%), Positives = 206/349 (59%), Gaps = 18/349 (5%)
Query: 10 SPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL-----HLW 64
S F DPG+ VWR+EK++ V G F+ GD Y++L V+ L H W
Sbjct: 5 SAFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILST--RRVASLLSQDIHFW 62
Query: 65 IGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESA 124
IG+ SS+DEQ A+ L+ LG PVQHREVQ +ESD F YF +G+ Y++GGV S
Sbjct: 63 IGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASG 122
Query: 125 FHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNI 184
T +K+L VKGK+NIRATE ++WDSFN GD F+LDLG+ I W G +SN
Sbjct: 123 MKHVETNT-YDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNS 181
Query: 185 LERNKARDLALAIRDSERQGKAQVEIVTDGEEPA--EMIQV----LGPKPALKEGNPEED 238
ER KA LA IRD ER G+A++ ++ +E A E+++V LG + +K P+E
Sbjct: 182 GERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEI 241
Query: 239 LTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKG 298
+ D+ LY +SD+ GQ+ +T+VA + P +LL DDC++LD KIY+WKG
Sbjct: 242 I--DQKQKSTIMLYHISDSAGQLAVTEVA-TRPLVQDLLNHDDCYILDQS-GTKIYVWKG 297
Query: 299 RKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDW 347
+ A + E+QAA+ A GFI Y +T VE + G ES +FKQ F+ W
Sbjct: 298 KGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKW 346
Score = 134 bits (336), Expect = 2e-31
Identities = 105/336 (31%), Positives = 163/336 (48%), Gaps = 30/336 (8%)
Query: 21 LHVWRVEKLKPVPVAQENQGVFFSGDSYLVLH----NG-PEEVSHLHLWIGQQSSRDEQG 75
+ VWR+E L+ VPV + G F+ GD YLVL+ NG P + L++W G+ +S+DE
Sbjct: 397 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHI--LYIWQGRHASQDELA 454
Query: 76 ACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAA 135
A A AV ++ VQ R G E FM+ F L EGG + P
Sbjct: 455 ASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTS----RKGNAEPDP 510
Query: 136 IKKLYQVKG--KKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDL 193
+L+Q+ G K N +A E S N+ D F+L + W G S+ ER A++L
Sbjct: 511 PVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKEL 570
Query: 194 ALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYK 253
A + D V +G+EPAE +LG K ++ L + + Q + L++
Sbjct: 571 ASLLCDGSE------NTVAEGQEPAEFWDLLGGKTPYAN---DKRLQQEILDVQ-SRLFE 620
Query: 254 VSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVA 313
S+ TGQ +T++ D F + L D +LD ++++W G +AN E+++AL A
Sbjct: 621 CSNKTGQFVVTEITD---FTQDDLNPTDVMLLDT--WDQVFLWIGAEANATEKESALATA 675
Query: 314 EGFISRMQYA--PNTQVEILPQGHESPIFKQFFKDW 347
+ ++ P+T + I+ QG E PIF +F W
Sbjct: 676 QQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAW 711
>gi|94721268 villin-like protein [Homo sapiens]
Length = 856
Score = 211 bits (536), Expect = 1e-54
Identities = 129/341 (37%), Positives = 193/341 (56%), Gaps = 19/341 (5%)
Query: 20 GLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLH--NGPEEV----SHLHLWIGQQSSRDE 73
GLH+W E K VPV + G FF Y++LH P+ S LH W+G+Q+ +
Sbjct: 13 GLHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSDLHYWVGKQAGAEA 72
Query: 74 QGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAP 133
QGA L LG + V HRE QG+ESD F SYF G+ Y++GG+ S T
Sbjct: 73 QGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLASDLKHVETNL- 131
Query: 134 AAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDL 193
I++L +KG+K++ ATE L+W+SFN GD F+LDLG+ + W G K++I E+ + L
Sbjct: 132 FNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARGLAL 191
Query: 194 ALAIRDSER-QGKAQVEIVTDGEEPAEMIQ----VLGPK-PALKEGNPEEDLT-ADKANA 246
++RD ER G+AQ+ +V D + +++Q VLG + +L+ P +D+ KAN
Sbjct: 192 TYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQKANV 251
Query: 247 QAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKER 306
+ LY V + + + ++A + P +LL +D ++LD G KIY+W+GR ++ +ER
Sbjct: 252 R---LYHVYEKGKDLVVLELA-TPPLTQDLLQEEDFYILDQG-GFKIYVWQGRMSSLQER 306
Query: 307 QAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDW 347
+AA A GFI Y T VE++ G ES FKQ F+ W
Sbjct: 307 KAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTW 347
Score = 89.0 bits (219), Expect = 6e-18
Identities = 89/332 (26%), Positives = 139/332 (41%), Gaps = 24/332 (7%)
Query: 21 LHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPE--EVSH-LHLWIGQQSSRDEQGAC 77
+ VW ++ L PV + G +G+ YLVL+ V + L+LW G Q++ DE A
Sbjct: 393 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEAL 452
Query: 78 AVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIK 137
A L+ + G VQ G+E F++ F L + E A H G A+
Sbjct: 453 NSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQ---ERAGHH-GKGQSASTT 508
Query: 138 KLYQVKG--KKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLAL 195
+L+QV+G N R E S N+ D F+L + W G N +R AR +
Sbjct: 509 RLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARVVVT 568
Query: 196 AIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVS 255
I + E V +G+EP + LG + P ++ + L++ S
Sbjct: 569 VI------SRKNEETVLEGQEPPHFWEALGGRAPY----PSNKRLPEEVPSFQPRLFECS 618
Query: 256 DATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEG 315
G + L +V F+ E L D +LD +I++W G A+E + A
Sbjct: 619 SHMGCLVLAEVGF---FSQEDLDKYDIMLLDT--WQEIFLWLGEAASEWKEAVAWGQEYL 673
Query: 316 FISRMQYAPNTQVEILPQGHESPIFKQFFKDW 347
+P T + ++ QGHE P F +F W
Sbjct: 674 KTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 705
>gi|4503743 flightless I homolog [Homo sapiens]
Length = 1269
Score = 148 bits (374), Expect = 6e-36
Identities = 102/351 (29%), Positives = 168/351 (47%), Gaps = 29/351 (8%)
Query: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQQSSRD 72
Q PGL +W++E PV V + G F+ D Y+VL ++ L + WIG +++ D
Sbjct: 497 QLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLD 556
Query: 73 EQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGA 132
++ A+ AV+L LG RE G+ES+ F+ F + Y EGG S F+
Sbjct: 557 KKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVED-- 614
Query: 133 PAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARD 192
+ ++Y+V GKKNI+ L S + F+LD G +I+ W G ++ + KAR
Sbjct: 615 THYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARL 674
Query: 193 LALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALY 252
A I +ER+GKA++ ++ G+E E + LG +P+ + + ED + LY
Sbjct: 675 FAEKINKNERKGKAEITLLVQGQELPEFWEALGGEPSEIKKHVPEDFWPPQPK-----LY 729
Query: 253 KVSDATGQMNLTKV-------------ADSSP--FALELLISDDC-FVLDNGLCGKIYIW 296
KV G + L ++ + P L+ L+ C ++LD ++IW
Sbjct: 730 KVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILD--CWSDVFIW 787
Query: 297 KGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDW 347
GRK+ R AAL++ + + + V +G E+ +FK FK+W
Sbjct: 788 LGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSLEGTEAQVFKAKFKNW 838
Score = 61.2 bits (147), Expect = 1e-09
Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 36/265 (13%)
Query: 96 REVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERA- 154
R Q E+ F+S+F R G K A LYQ++ + T
Sbjct: 1020 RMTQQQENPKFLSHFKRKFIIHRG-------KRKAVQGAQQPSLYQIRTNGSALCTRCIQ 1072
Query: 155 LNWDS--FNTGDCFIL-------DLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGK 205
+N DS N+ CFIL D ++AW G S+ E A D+ + D+
Sbjct: 1073 INTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNTMFDTSYSK- 1131
Query: 206 AQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNLTK 265
+++ +GEEP V + P +D D + L++ S+ G +T+
Sbjct: 1132 ---QVINEGEEPENFFWV-----GIGAQKPYDD---DAEYMKHTRLFRCSNEKGYFAVTE 1180
Query: 266 VADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRM---QY 322
S F + L DD +LDNG ++Y+W G + ++ E + +L+ + +I M ++
Sbjct: 1181 KC--SDFCQDDLADDDIMLLDNGQ--EVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEH 1236
Query: 323 APNTQVEILPQGHESPIFKQFFKDW 347
++ ++ +G+E F + F W
Sbjct: 1237 ERPRRLRLVRKGNEQHAFTRCFHAW 1261
Score = 30.4 bits (67), Expect = 2.5
Identities = 36/163 (22%), Positives = 72/163 (44%), Gaps = 20/163 (12%)
Query: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
++ W+G+ S DE + LNT+ + +G E + ++F G+ Q+
Sbjct: 1101 VYAWVGRASDPDEAKLAEDI---LNTMFDTSYSKQVINEGEEPE---NFFWVGIGAQKPY 1154
Query: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRA-TERALNW--DSFNTGDCFILDLGQNIFAW 177
+ A + T +L++ +K A TE+ ++ D D +LD GQ ++ W
Sbjct: 1155 DDDAEYMKHT-------RLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMW 1207
Query: 178 CGGKSNILERN---KARDLALA-IRDSERQGKAQVEIVTDGEE 216
G +++ +E KA + + +R E + ++ +V G E
Sbjct: 1208 VGTQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVRKGNE 1250
>gi|14916473 scinderin isoform 2 [Homo sapiens]
Length = 468
Score = 129 bits (325), Expect = 3e-30
Identities = 53/100 (53%), Positives = 82/100 (82%)
Query: 249 AALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQA 308
A LY VSDA+G M +T VA+ +PF++ +L+S++CF+LD+G +I++WKG+ AN +ER+A
Sbjct: 2 AKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKA 61
Query: 309 ALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
A++ AE F+ +M Y+ NTQ+++LP+G E+PIFKQFFKDW+
Sbjct: 62 AMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWR 101
Score = 118 bits (295), Expect = 9e-27
Identities = 99/335 (29%), Positives = 155/335 (46%), Gaps = 30/335 (8%)
Query: 21 LHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVL 80
+ +WRVE + V Q + G F+ GD Y++L+ P ++ W G ++RDE A L
Sbjct: 151 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTTSAFL 209
Query: 81 AVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSTGAPAAIKKL 139
V L+ LG + VQ R QG E +S F + L + G K APA +L
Sbjct: 210 TVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTS----KKGGQAPAPPTRL 265
Query: 140 YQVKGKKNIRATERALNWD----SFNTGDCFILDLGQNI-FAWCGGKSNILERNKARDLA 194
+QV ++N+ + R + D S N+ D F+L L QN + W G ++ E A +A
Sbjct: 266 FQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 323
Query: 195 LAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKV 254
+ K + + +GEEP E LG K+ L +A LY
Sbjct: 324 SVL-------KCKTLRIQEGEEPEEFWNSLGG----KKDYQTSPLLETQAEDHPPRLYGC 372
Query: 255 SDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAE 314
S+ TG+ + ++ F + L DD +LD +I+IW G+ ANE E++ +L+ A+
Sbjct: 373 SNKTGRFVIEEI--PGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAK 428
Query: 315 GFISRMQYA--PNTQVEILPQGHESPIFKQFFKDW 347
++ T + I+ QGHE P F +F W
Sbjct: 429 MYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463
>gi|150417973 supervillin isoform 2 [Homo sapiens]
Length = 2214
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/227 (21%), Positives = 100/227 (44%), Gaps = 22/227 (9%)
Query: 126 HKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNIL 185
+ ++ P L Q+KG+++++ + N+GDCF+L F W G +N++
Sbjct: 1432 NSNNSAVPYKRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVI 1491
Query: 186 ERNKARDLALAIRDSERQG--KAQVEIVTDG-----EEPAEMIQVLGPKPALKE-GNPEE 237
E+ KA +LA I+ G ++ + +G + ++LG + + + G+P+E
Sbjct: 1492 EKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKE 1551
Query: 238 DLTADKANAQAAALYKVSDATGQMNLTKVADSSPF-----ALELLISDDCFVLDNGLCGK 292
D + A + +Y++ D K+ + LL + V D G +
Sbjct: 1552 DELYEAAIIETNCIYRLMD-------DKLVPDDDYWGKIPKCSLLQPKEVLVFDFG--SE 1602
Query: 293 IYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPI 339
+Y+W G++ +R+ A Q+A+ + N + L G +P+
Sbjct: 1603 VYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPL 1649
Score = 46.2 bits (108), Expect = 4e-05
Identities = 69/320 (21%), Positives = 121/320 (37%), Gaps = 59/320 (18%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLV-------------------LHNGPEEVSHLHL 63
VW + + + +++ G F GD+Y+V + +E
Sbjct: 1756 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1815
Query: 64 WIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVES 123
W G+ S+ E+G A++ V L+ ER Q + +QG E F+ F G+ G E
Sbjct: 1816 WQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREE 1872
Query: 124 AFHKTSTGAPAAIKKLYQVKGKKNIRAT--ERALNWDSFNTGDCFILDLGQN---IFAWC 178
+ +LY V+G+ + E A + S + ++ L N I+ W
Sbjct: 1873 EEENVQSE-----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLWH 1926
Query: 179 GGKSNILERNKARDLALAIRDS-------ERQGKAQVEIVTDGEEPAEMIQVLGPKPALK 231
G K+ + R A I++ K + +G EP LG +
Sbjct: 1927 GCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG----RR 1982
Query: 232 EGNPEEDLTADKANAQ-AAALYKVSDATGQMNLTK---------VADSSPFALELLIS-- 279
+ + + D + A L+ +S ++G T+ V S PF E L S
Sbjct: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042
Query: 280 -DDCFVLDNGLCGKIYIWKG 298
F++DN ++Y+W+G
Sbjct: 2043 QPALFLVDNH--HEVYLWQG 2060
>gi|150417971 supervillin isoform 1 [Homo sapiens]
Length = 1788
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/227 (21%), Positives = 100/227 (44%), Gaps = 22/227 (9%)
Query: 126 HKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNIL 185
+ ++ P L Q+KG+++++ + N+GDCF+L F W G +N++
Sbjct: 1006 NSNNSAVPYKRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVI 1065
Query: 186 ERNKARDLALAIRDSERQG--KAQVEIVTDG-----EEPAEMIQVLGPKPALKE-GNPEE 237
E+ KA +LA I+ G ++ + +G + ++LG + + + G+P+E
Sbjct: 1066 EKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKE 1125
Query: 238 DLTADKANAQAAALYKVSDATGQMNLTKVADSSPF-----ALELLISDDCFVLDNGLCGK 292
D + A + +Y++ D K+ + LL + V D G +
Sbjct: 1126 DELYEAAIIETNCIYRLMD-------DKLVPDDDYWGKIPKCSLLQPKEVLVFDFG--SE 1176
Query: 293 IYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPI 339
+Y+W G++ +R+ A Q+A+ + N + L G +P+
Sbjct: 1177 VYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPL 1223
Score = 46.2 bits (108), Expect = 4e-05
Identities = 69/320 (21%), Positives = 121/320 (37%), Gaps = 59/320 (18%)
Query: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLV-------------------LHNGPEEVSHLHL 63
VW + + + +++ G F GD+Y+V + +E
Sbjct: 1330 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1389
Query: 64 WIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVES 123
W G+ S+ E+G A++ V L+ ER Q + +QG E F+ F G+ G E
Sbjct: 1390 WQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREE 1446
Query: 124 AFHKTSTGAPAAIKKLYQVKGKKNIRAT--ERALNWDSFNTGDCFILDLGQN---IFAWC 178
+ +LY V+G+ + E A + S + ++ L N I+ W
Sbjct: 1447 EEENVQSE-----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLWH 1500
Query: 179 GGKSNILERNKARDLALAIRDS-------ERQGKAQVEIVTDGEEPAEMIQVLGPKPALK 231
G K+ + R A I++ K + +G EP LG +
Sbjct: 1501 GCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG----RR 1556
Query: 232 EGNPEEDLTADKANAQ-AAALYKVSDATGQMNLTK---------VADSSPFALELLIS-- 279
+ + + D + A L+ +S ++G T+ V S PF E L S
Sbjct: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
Query: 280 -DDCFVLDNGLCGKIYIWKG 298
F++DN ++Y+W+G
Sbjct: 1617 QPALFLVDNH--HEVYLWQG 1634
>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
Length = 1388
Score = 33.1 bits (74), Expect = 0.38
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 204 GKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNL 263
G A+V I T GE A + GP ++ NPEE +T N + A +A ++
Sbjct: 363 GLAEVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASM 422
Query: 264 TKVADSS---PFALELLIS 279
++S P L+L +S
Sbjct: 423 PGEVEASGVAPGELDLSMS 441
>gi|239750652 PREDICTED: hypothetical protein XP_002347499 [Homo
sapiens]
Length = 166
Score = 30.4 bits (67), Expect = 2.5
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 179 GGKSNILERNKARDLALAIRDSERQGKAQVEIVTDG-EEPAEMIQVLGPKPALKEGNPEE 237
GG+S AR L L R S R+G+ + E T+G + ++ + A +EG EE
Sbjct: 49 GGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEE 108
Query: 238 DLTADKANA 246
A +A A
Sbjct: 109 GAGAREAGA 117
>gi|239744960 PREDICTED: hypothetical protein XP_002343317 [Homo
sapiens]
Length = 166
Score = 30.4 bits (67), Expect = 2.5
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 179 GGKSNILERNKARDLALAIRDSERQGKAQVEIVTDG-EEPAEMIQVLGPKPALKEGNPEE 237
GG+S AR L L R S R+G+ + E T+G + ++ + A +EG EE
Sbjct: 49 GGQSRCCSVVAARLLRLTPRSSARRGRPESEPATNGTRQQGDLPALSAAAEAPREGGKEE 108
Query: 238 DLTADKANA 246
A +A A
Sbjct: 109 GAGAREAGA 117
>gi|154744870 zinc finger protein 574 [Homo sapiens]
Length = 896
Score = 29.6 bits (65), Expect = 4.2
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 7/50 (14%)
Query: 290 CGKIY-----IWKGRKANEKERQAAL--QVAEGFISRMQYAPNTQVEILP 332
CGK Y +WK RK ++++ QAA+ Q+AE + T VE LP
Sbjct: 827 CGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAEAAVGLAVMETAVEALP 876
>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
sapiens]
Length = 1977
Score = 29.3 bits (64), Expect = 5.5
Identities = 14/53 (26%), Positives = 26/53 (49%), Gaps = 5/53 (9%)
Query: 17 QDPGLHVWRVEKLKPVPVAQEN-----QGVFFSGDSYLVLHNGPEEVSHLHLW 64
+DP +H+W E +KP+ + + + V FS D + G ++ + LW
Sbjct: 749 RDPSIHIWDTETIKPLSILKGHHQYGVSAVDFSADGKRLASVGIDDSHTVVLW 801
>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
Length = 1537
Score = 28.9 bits (63), Expect = 7.1
Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 14/107 (13%)
Query: 50 VLHNGPEEVSHLHLWIGQQSSRDEQGACAVL---AVHLNTLLGERPVQHRE-----VQGN 101
+L NG E+VS W R + + H+ TL+G + +QHR +GN
Sbjct: 1340 ILDNGQEDVSPSGQWNPYPLGRRDVPPDTITKKAGSHIQTLMGSQSLQHRSREQQPYEGN 1399
Query: 102 ESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNI 148
+ + + F L Q + S+ +T P + L Q KG++++
Sbjct: 1400 INKVTIQQFQSPLPIQ---IPSS---QATRGPQPGRCLIQTKGQRSM 1440
>gi|51317380 D-glucuronyl C5-epimerase [Homo sapiens]
Length = 617
Score = 28.9 bits (63), Expect = 7.1
Identities = 11/22 (50%), Positives = 16/22 (72%)
Query: 327 QVEILPQGHESPIFKQFFKDWK 348
Q+++L ESP+FK+F K WK
Sbjct: 585 QLQLLSTIDESPVFKEFVKRWK 606
>gi|32129212 zinc finger protein 434 [Homo sapiens]
Length = 485
Score = 28.5 bits (62), Expect = 9.3
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 19/86 (22%)
Query: 15 SVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLV----LHNG--PEEVSHLHLWIGQQ 68
SV P ++EK+ P G FS SYLV +H G P + S ++
Sbjct: 294 SVHSPHKPALKLEKVSQCPEC----GKTFSRSSYLVRHQRIHTGEKPHKCSECGKGFSER 349
Query: 69 SSRDEQGACAVLAVHLNTLLGERPVQ 94
S+ L HL T GERP Q
Sbjct: 350 SN---------LTAHLRTHTGERPYQ 366
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,164,028
Number of Sequences: 37866
Number of extensions: 648666
Number of successful extensions: 1645
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1455
Number of HSP's gapped (non-prelim): 43
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.