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Search of human proteins with 62912476
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62912476 lethal giant larvae homolog 1 [Homo sapiens]
(1064 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62912476 lethal giant larvae homolog 1 [Homo sapiens] 2142 0.0
gi|73427803 lethal giant larvae homolog 2 isoform c [Homo sapiens] 1099 0.0
gi|62739161 lethal giant larvae homolog 2 isoform a [Homo sapiens] 1099 0.0
gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Hom... 356 6e-98
gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Hom... 347 3e-95
gi|62739163 lethal giant larvae homolog 2 isoform b [Homo sapiens] 343 6e-94
gi|149363700 syntaxin binding protein 5-like [Homo sapiens] 327 3e-89
gi|53759148 retinoblastoma binding protein 5 [Homo sapiens] 37 0.076
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 37 0.099
gi|21536371 telomerase-associated protein 1 [Homo sapiens] 35 0.49
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 34 0.64
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 33 1.1
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 33 1.4
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 33 1.4
gi|55743108 ATG16 autophagy related 16-like 2 [Homo sapiens] 33 1.4
gi|238859557 regulatory factor X1 [Homo sapiens] 33 1.9
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 33 1.9
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 33 1.9
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 33 1.9
gi|46559747 hypothetical protein LOC399947 [Homo sapiens] 33 1.9
gi|23199987 WD repeat domain 5B [Homo sapiens] 33 1.9
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 32 2.4
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 32 2.4
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 32 2.4
gi|239049440 FCH domain only 1 isoform a [Homo sapiens] 32 2.4
gi|156139122 CXXC finger 6 [Homo sapiens] 32 2.4
gi|4503519 eukaryotic translation initiation factor 3, subunit 5... 32 2.4
gi|4507103 small nuclear RNA activating complex, polypeptide 2, ... 32 2.4
gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific ... 32 3.2
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 32 3.2
>gi|62912476 lethal giant larvae homolog 1 [Homo sapiens]
Length = 1064
Score = 2142 bits (5551), Expect = 0.0
Identities = 1064/1064 (100%), Positives = 1064/1064 (100%)
Query: 1 MMKFRFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI 60
MMKFRFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI
Sbjct: 1 MMKFRFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI 60
Query: 61 YGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQ 120
YGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQ
Sbjct: 61 YGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQ 120
Query: 121 LPSRPGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGE 180
LPSRPGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGE
Sbjct: 121 LPSRPGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGE 180
Query: 181 VLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQL 240
VLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQL
Sbjct: 181 VLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQL 240
Query: 241 ESLCWGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCE 300
ESLCWGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCE
Sbjct: 241 ESLCWGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCE 300
Query: 301 SGGHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQA 360
SGGHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQA
Sbjct: 301 SGGHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQA 360
Query: 361 LAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQS 420
LAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQS
Sbjct: 361 LAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQS 420
Query: 421 PQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQ 480
PQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQ
Sbjct: 421 PQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQ 480
Query: 481 TDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLV 540
TDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLV
Sbjct: 481 TDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLV 540
Query: 541 LELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAA 600
LELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAA
Sbjct: 541 LELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAA 600
Query: 601 VTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSL 660
VTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSL
Sbjct: 601 VTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSL 660
Query: 661 RQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS 720
RQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS
Sbjct: 661 RQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS 720
Query: 721 GVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGK 780
GVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGK
Sbjct: 721 GVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGK 780
Query: 781 EVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPK 840
EVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPK
Sbjct: 781 EVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPK 840
Query: 841 VSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVH 900
VSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVH
Sbjct: 841 VSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVH 900
Query: 901 YSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQA 960
YSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQA
Sbjct: 901 YSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQA 960
Query: 961 SYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSAD 1020
SYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSAD
Sbjct: 961 SYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSAD 1020
Query: 1021 TTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK 1064
TTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK
Sbjct: 1021 TTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK 1064
>gi|73427803 lethal giant larvae homolog 2 isoform c [Homo sapiens]
Length = 1020
Score = 1099 bits (2843), Expect = 0.0
Identities = 557/947 (58%), Positives = 693/947 (73%), Gaps = 14/947 (1%)
Query: 5 RFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAP 64
RF R G DP RE+LK++LF FNKTVEHGFP+QPSAL + P LRI+AIGTRSGA+K+YGAP
Sbjct: 3 RFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAP 62
Query: 65 GVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSR 124
GVEF GLH++ VTQ+H L GQ +L++LLDD+SLHLW + G + L+E SF L
Sbjct: 63 GVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGP 122
Query: 125 PGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRS 184
PG +AP S T++TVVL ++ ++ LGTE +VF + + LE +T++ VL+
Sbjct: 123 PG----AAP-SATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQR 177
Query: 185 VPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLC 244
+P++ R + VE+LQ H RDP +ILIGYSRGL+VIW+ V + FL +QQLE++
Sbjct: 178 LPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIW 237
Query: 245 WGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGH 304
W RD +VS HSDGSY W V + + +P + PYGPFPCKAI +ILW G
Sbjct: 238 WQRDGRLLVSCHSDGSYCQWPVSSEAQQP-EPLRSLVPYGPFPCKAITRILWLTTRQGLP 296
Query: 305 FIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVL 364
F IF GGMPRASYGDRHC+SV+ DFTSR+I F + P FDDP AL VL
Sbjct: 297 FTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVL 356
Query: 365 LEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPV 424
EEELVV+DLQT GWP V PYLA LH SAITCS HV+++P KLW RI++AG +Q+
Sbjct: 357 AEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAH-- 414
Query: 425 SSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCE 484
S + WPI GG +L P QR LLLTGHEDGTVRFWDASGV LR LYKLST +F TD +
Sbjct: 415 FSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTD 474
Query: 485 HADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELS 544
++ + ED+WPP RKVG FDPYSDDPRLG+QK+ LCKY+ + VAGTAGQVLVLEL+
Sbjct: 475 PNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELN 534
Query: 545 DVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAAVTAV 604
D EQAV DLLQD+EG+ WKGHERL+ R+GP+ + GFQP VLVQC PPA VT++
Sbjct: 535 DEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSL 594
Query: 605 TLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSF 664
LH+EW LVAFGTSHGFGLFD+Q++ V +CTLHP+D LA+EGPLSRVKSLKKSLRQSF
Sbjct: 595 ALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSF 654
Query: 665 RRIRKSRVSGKKR-AANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLSGVV 723
RR+R+SRVS +KR A + QE +A+ AE+ ++E+ PVQR+IE RSA+DS +G V
Sbjct: 655 RRMRRSRVSSRKRHPAGPPGEAQEGSAK-AERPGLQNMELAPVQRKIEARSAEDSFTGFV 713
Query: 724 RCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQ 783
R LYFADT+L+D + H P++WAGTN G+++A++L VP A E+R ++ V A KE+Q
Sbjct: 714 RTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPA----ERRMDEPVRAEQAKEIQ 769
Query: 784 LMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSA 843
LMHRAPVV I VLDG PLPEP E + DL+++PDMQG H +L+ SEEQFKVFTLPKVSA
Sbjct: 770 LMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA 829
Query: 844 KTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVHYSC 903
K K KLTA EG RVR+V++A F S EDY E LA LTNLGD+ V S+P L+PQV YSC
Sbjct: 830 KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSC 889
Query: 904 IRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLD 950
IR+ED+SGIASCVFT++GQGFYLISPSEFERFSLS + + EP C +D
Sbjct: 890 IRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVD 936
>gi|62739161 lethal giant larvae homolog 2 isoform a [Homo sapiens]
Length = 1015
Score = 1099 bits (2843), Expect = 0.0
Identities = 557/947 (58%), Positives = 693/947 (73%), Gaps = 14/947 (1%)
Query: 5 RFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAP 64
RF R G DP RE+LK++LF FNKTVEHGFP+QPSAL + P LRI+AIGTRSGA+K+YGAP
Sbjct: 3 RFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAP 62
Query: 65 GVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSR 124
GVEF GLH++ VTQ+H L GQ +L++LLDD+SLHLW + G + L+E SF L
Sbjct: 63 GVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGP 122
Query: 125 PGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRS 184
PG +AP S T++TVVL ++ ++ LGTE +VF + + LE +T++ VL+
Sbjct: 123 PG----AAP-SATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQR 177
Query: 185 VPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLC 244
+P++ R + VE+LQ H RDP +ILIGYSRGL+VIW+ V + FL +QQLE++
Sbjct: 178 LPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIW 237
Query: 245 WGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGH 304
W RD +VS HSDGSY W V + + +P + PYGPFPCKAI +ILW G
Sbjct: 238 WQRDGRLLVSCHSDGSYCQWPVSSEAQQP-EPLRSLVPYGPFPCKAITRILWLTTRQGLP 296
Query: 305 FIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVL 364
F IF GGMPRASYGDRHC+SV+ DFTSR+I F + P FDDP AL VL
Sbjct: 297 FTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVL 356
Query: 365 LEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPV 424
EEELVV+DLQT GWP V PYLA LH SAITCS HV+++P KLW RI++AG +Q+
Sbjct: 357 AEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAH-- 414
Query: 425 SSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCE 484
S + WPI GG +L P QR LLLTGHEDGTVRFWDASGV LR LYKLST +F TD +
Sbjct: 415 FSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTD 474
Query: 485 HADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELS 544
++ + ED+WPP RKVG FDPYSDDPRLG+QK+ LCKY+ + VAGTAGQVLVLEL+
Sbjct: 475 PNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELN 534
Query: 545 DVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAAVTAV 604
D EQAV DLLQD+EG+ WKGHERL+ R+GP+ + GFQP VLVQC PPA VT++
Sbjct: 535 DEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSL 594
Query: 605 TLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSF 664
LH+EW LVAFGTSHGFGLFD+Q++ V +CTLHP+D LA+EGPLSRVKSLKKSLRQSF
Sbjct: 595 ALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSF 654
Query: 665 RRIRKSRVSGKKR-AANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLSGVV 723
RR+R+SRVS +KR A + QE +A+ AE+ ++E+ PVQR+IE RSA+DS +G V
Sbjct: 655 RRMRRSRVSSRKRHPAGPPGEAQEGSAK-AERPGLQNMELAPVQRKIEARSAEDSFTGFV 713
Query: 724 RCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQ 783
R LYFADT+L+D + H P++WAGTN G+++A++L VP A E+R ++ V A KE+Q
Sbjct: 714 RTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPA----ERRMDEPVRAEQAKEIQ 769
Query: 784 LMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSA 843
LMHRAPVV I VLDG PLPEP E + DL+++PDMQG H +L+ SEEQFKVFTLPKVSA
Sbjct: 770 LMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA 829
Query: 844 KTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVHYSC 903
K K KLTA EG RVR+V++A F S EDY E LA LTNLGD+ V S+P L+PQV YSC
Sbjct: 830 KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSC 889
Query: 904 IRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLD 950
IR+ED+SGIASCVFT++GQGFYLISPSEFERFSLS + + EP C +D
Sbjct: 890 IRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVD 936
>gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Homo
sapiens]
Length = 1115
Score = 356 bits (914), Expect = 6e-98
Identities = 285/1023 (27%), Positives = 456/1023 (44%), Gaps = 151/1023 (14%)
Query: 15 REKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRD 74
+E L+ E F KTV HGFP QPSALAFDP +I+A+GT++GA++++G PGVE H
Sbjct: 38 QETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDS 97
Query: 75 AATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGASAPL 134
A V Q+ FL +G L+S L D +LHLW + RP S
Sbjct: 98 GAAVIQLQFLINEGALVSALADDTLHLWNLRQ----------------KRPAILH-SLKF 140
Query: 135 SLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRSVPDDYRCGKA 194
RVT L +GTE ++ ++V + TL G + + + +
Sbjct: 141 CRERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTL-SGYVIMWNKAIELSSKSHP---- 195
Query: 195 LGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLCWGRDSSTVVS 254
GPV + + D K+LIG+ G +V+W+ S+ D+ + ++ + S+ W + +
Sbjct: 196 -GPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFIC 254
Query: 255 SHSDGSYAVWSVDAGSFPTLQPTVATTPYG--------PFPCKAINKILWRNCESGGHFI 306
SHSDG+ +W+V + + +P TP+G P PCK I K+ ++ SG FI
Sbjct: 255 SHSDGTLTIWNVRSPA----KPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFI 310
Query: 307 IFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLE 366
I SGG+ + G R C++V+ ++ L+ I+DF T+ T ++F +P A+ VLLE
Sbjct: 311 ILSGGLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLE 370
Query: 367 EELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSS 426
++LV++DL G+P PY +H S +TC + A P L + S G +Q Q S
Sbjct: 371 KDLVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSK 430
Query: 427 ALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEHA 486
WPI GG S +++TGH DG+V+FWDAS + L+ LYKL T+ +F+
Sbjct: 431 K-EWPINGGNWGLGAQSYPEIIITGHADGSVKFWDASAITLQVLYKLKTSKVFE------ 483
Query: 487 DSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSDV 546
++ D P + DPY+ +Q ++ C + + +AG + V++ S
Sbjct: 484 ----KSRNKDDRPNTDIVDEDPYA------IQIISWCPESRMLCIAGVSAHVIIYRFS-- 531
Query: 547 PVEQAVSVAIIDLLQDR------EGFTWKGHER--------------------------- 573
+Q V +I +L+ R + T +G +
Sbjct: 532 --KQEVITEVIPMLEVRLLYEINDVETPEGEQPPPLPTPVGGSNPQPIPPQSHPSTSSSS 589
Query: 574 ----------LSPRTGPLPWPAGFQPRVLVQCL-----PPAAVTAVTLHTEWSLVAFGTS 618
L + PL G+Q +++Q + PP +T++ +++ + LV FG
Sbjct: 590 SDGLRDNVPCLKVKNSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNC 649
Query: 619 HGFGLFDYQRKSPVLARCTLH---PNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGK 675
+G + DY +K+ +L T+ ND E P S KS + S I + V +
Sbjct: 650 NGIAMVDYLQKAVLLNLGTIELYGSNDPYRRE-PRSPRKSRQPS-GAGLCDISEGTVVPE 707
Query: 676 KRAANASSKLQEANAQLAEQACPH-DVEMTPV--QRRIEPRSADDSLSGVVRCLYFADTF 732
R + +S L P DV+ R S D + L+F +TF
Sbjct: 708 DRCKSPTSAKMSRKLSLPTDLKPDLDVKDNSFSRSRSSSVTSIDKESREAISALHFCETF 767
Query: 733 LR-DGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQLMHRAPVV 791
R + P +W GT G+V AL +P GGE+R Q V V L + ++
Sbjct: 768 TRKTDSSPSPCLWVGTTLGTVLVIALNLPP---GGEQRLLQPV-IVSPSGTILRLKGAIL 823
Query: 792 AIAVLDGRGRPLPEPYEASRD----------------------LAQAPDMQGGHAVLIAS 829
+A LD G +P YE R+ + + ++ +I S
Sbjct: 824 RMAFLDTTGCLIPPAYEPWREHNVPEEKDEKEKLKKRRPVSVSPSSSQEISENQYAVICS 883
Query: 830 EEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHV 889
E+Q KV +LP + K +T E V + + ++ CLAC G +
Sbjct: 884 EKQAKVISLPTQNCAYKQNIT--ETSFVLRGDIVALSN-------SICLACFCANGHIMT 934
Query: 890 FSVPGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLS---ARNITEPL 946
FS+P LRP + + ++ + FT +GQ YL+SP+E +R + S N+ E L
Sbjct: 935 FSLPSLRPLLDVYYLPLTNMRIARTFCFTNNGQALYLVSPTEIQRLTYSQETCENLQEML 994
Query: 947 CSL 949
L
Sbjct: 995 GEL 997
>gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Homo
sapiens]
Length = 1151
Score = 347 bits (891), Expect = 3e-95
Identities = 282/1057 (26%), Positives = 458/1057 (43%), Gaps = 183/1057 (17%)
Query: 15 REKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRD 74
+E L+ E F KTV HGFP QPSALAFDP +I+A+GT++GA++++G PGVE H
Sbjct: 38 QETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDS 97
Query: 75 AATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGASAPL 134
A V Q+ FL +G L+S L D +LHLW + RP S
Sbjct: 98 GAAVIQLQFLINEGALVSALADDTLHLWNLRQ----------------KRPAILH-SLKF 140
Query: 135 SLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRSVPDDYRCGKA 194
RVT L +GTE ++ ++V + TL G + + + +
Sbjct: 141 CRERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTL-SGYVIMWNKAIELSSKSHP---- 195
Query: 195 LGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLCWGRDSSTVVS 254
GPV + + D K+LIG+ G +V+W+ S+ D+ + ++ + S+ W + +
Sbjct: 196 -GPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFIC 254
Query: 255 SHSDGSYAVWSVDAGSFPTLQPTVATTPYG--------PFPCKAINKILWRNCESGGHFI 306
SHSDG+ +W+V + + +P TP+G P PCK I K+ ++ SG FI
Sbjct: 255 SHSDGTLTIWNVRSPA----KPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFI 310
Query: 307 IFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLE 366
I SGG+ + G R C++V+ ++ L+ I+DF T+ T ++F +P A+ VLLE
Sbjct: 311 ILSGGLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLE 370
Query: 367 EELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSS 426
++LV++DL G+P PY +H S +TC + A P L + S G +Q Q S
Sbjct: 371 KDLVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSK 430
Query: 427 ALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEHA 486
WPI GG S +++TGH DG+V+FWDAS + L+ LYKL T+ +F+
Sbjct: 431 K-EWPINGGNWGLGAQSYPEIIITGHADGSVKFWDASAITLQVLYKLKTSKVFE------ 483
Query: 487 DSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSDV 546
++ D P + DPY+ +Q ++ C + + +AG + V++ S
Sbjct: 484 ----KSRNKDDRPNTDIVDEDPYA------IQIISWCPESRMLCIAGVSAHVIIYRFS-- 531
Query: 547 PVEQAVSVAIIDLLQDR------EGFTWKGHER--------------------------- 573
+Q V +I +L+ R + T +G +
Sbjct: 532 --KQEVITEVIPMLEVRLLYEINDVETPEGEQPPPLPTPVGGSNPQPIPPQSHPSTSSSS 589
Query: 574 ----------LSPRTGPLPWPAGFQPRVLVQCL-----PPAAVTAVTLHTEWSLVAFGTS 618
L + PL G+Q +++Q + PP +T++ +++ + LV FG
Sbjct: 590 SDGLRDNVPCLKVKNSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNC 649
Query: 619 HGFGLFDYQRKSPVLARCTLH--------------PNDSLAMEG------------PLSR 652
+G + DY +K+ +L T+ P S G P R
Sbjct: 650 NGIAMVDYLQKAVLLNLGTIELYGSNDPYRREPRSPRKSRQPSGAGLCDISEGTVVPEDR 709
Query: 653 VKSL------------KKSLRQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHD 700
KS ++ + +++ K AN +K+ + + D
Sbjct: 710 CKSPTSGSSSPHNSDDEQKMNNFIEKVKTKSRKFSKMVANDIAKMSRKLSLPTDLKPDLD 769
Query: 701 VEMTPV--QRRIEPRSADDSLSGVVRCLYFADTFLR-DGAHHGPTMWAGTNSGSVFAYAL 757
V+ R S D + L+F +TF R + P +W GT G+V AL
Sbjct: 770 VKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKTDSSPSPCLWVGTTLGTVLVIAL 829
Query: 758 EVPAAAVGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRD----- 812
+P GGE+R Q V V L + ++ +A LD G +P YE R+
Sbjct: 830 NLPP---GGEQRLLQPV-IVSPSGTILRLKGAILRMAFLDTTGCLIPPAYEPWREHNVPE 885
Query: 813 -----------------LAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGC 855
+ + ++ +I SE+Q KV +LP + K +T E
Sbjct: 886 EKDEKEKLKKRRPVSVSPSSSQEISENQYAVICSEKQAKVISLPTQNCAYKQNIT--ETS 943
Query: 856 RVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKEDISGIASC 915
V + + ++ CLAC G + FS+P LRP + + ++ +
Sbjct: 944 FVLRGDIVALSN-------SICLACFCANGHIMTFSLPSLRPLLDVYYLPLTNMRIARTF 996
Query: 916 VFTRHGQGFYLISPSEFERFSLS---ARNITEPLCSL 949
FT +GQ YL+SP+E +R + S N+ E L L
Sbjct: 997 CFTNNGQALYLVSPTEIQRLTYSQETCENLQEMLGEL 1033
>gi|62739163 lethal giant larvae homolog 2 isoform b [Homo sapiens]
Length = 356
Score = 343 bits (879), Expect = 6e-94
Identities = 178/347 (51%), Positives = 232/347 (66%), Gaps = 6/347 (1%)
Query: 5 RFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAP 64
RF R G DP RE+LK++LF FNKTVEHGFP+QPSAL + P LRI+AIGTRSGA+K+YGAP
Sbjct: 3 RFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAP 62
Query: 65 GVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSR 124
GVEF GLH++ VTQ+H L GQ +L++LLDD+SLHLW + G + L+E SF L
Sbjct: 63 GVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGP 122
Query: 125 PGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRS 184
PG +AP S T++TVVL ++ ++ LGTE +VF + + LE +T++ VL+
Sbjct: 123 PG----AAP-SATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQR 177
Query: 185 VPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLC 244
+P++ R + VE+LQ H RDP +ILIGYSRGL+VIW+ V + FL +QQLE++
Sbjct: 178 LPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIW 237
Query: 245 WGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGH 304
W RD +VS HSDGSY W V + + +P + PYGPFPCKAI +ILW G
Sbjct: 238 WQRDGRLLVSCHSDGSYCQWPVSSEA-QQPEPLRSLVPYGPFPCKAITRILWLTTRQGLP 296
Query: 305 FIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRP 351
F IF GGMPRASYGDRHC+SV+ DFTSR+I F + P
Sbjct: 297 FTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADP 343
>gi|149363700 syntaxin binding protein 5-like [Homo sapiens]
Length = 1186
Score = 327 bits (839), Expect = 3e-89
Identities = 281/1051 (26%), Positives = 456/1051 (43%), Gaps = 174/1051 (16%)
Query: 15 REKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRD 74
+E L E F KTV HGFP+QP+ALAFDP +I+AIGTR+GA++I G PGV+ H
Sbjct: 51 QETLTSEYFQICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHES 110
Query: 75 AATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGASAPL 134
A V Q+ FL +G L+S D +LHLW + RP S
Sbjct: 111 GAAVLQLQFLINEGALVSASSDDTLHLWNLRQ----------------KRPAILH-SLKF 153
Query: 135 SLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRSVPDDYRCGKA 194
+ R+T L +GTE + +++ + +L G + + + +
Sbjct: 154 NRERITYCHLPFQSKWLYVGTERGNTHIVNIESF-ILSGYVIMWNKAIELSTKTHP---- 208
Query: 195 LGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLCWGRDSSTVVS 254
GPV L RD K+LIGY G +V W+ S+ + ++ + S+ W + +
Sbjct: 209 -GPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHHEGKQFMC 267
Query: 255 SHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFP--------CKAINKILWRNCESGGHFI 306
SHSDGS +W++ + S +P T P+G CK I K+ ++ C++ FI
Sbjct: 268 SHSDGSLTLWNLKSPS----RPFQTTIPHGKSQREGRKSESCKPILKVEYKTCKNSEPFI 323
Query: 307 IFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLE 366
IFSGG+ R ++++ + + L+ I++F T+ T +EF +P A+ VLLE
Sbjct: 324 IFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVVVLLE 383
Query: 367 EELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSS 426
++L+V+DL +P PY +H S +TC+A+ A P L + S G + Q S+
Sbjct: 384 KDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSN 443
Query: 427 ALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTD-CEH 485
WPI+GG + +++TGH DG+++FWDAS + L+ LYKL T+ +F+
Sbjct: 444 K-EWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASAITLQMLYKLKTSKVFEKQKVGE 502
Query: 486 ADSLAQAAEDD--------WPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQ 537
+ E+D W P ++ C S + + K + + T ++V Q
Sbjct: 503 GKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVS--AYVIIYKFSRHEITTEIVSLEVRLQ 560
Query: 538 VLVLELSDVPVEQAVSVAIIDLLQD---------------REGFTWKGHERLSPRTGPLP 582
V ++ + E S DL EG T L+ +T P+
Sbjct: 561 YDVEDI--ITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVKTRPVR 618
Query: 583 WPAGFQPRVLVQCL-----PPAAVTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCT 637
P G+Q +++Q + PP +T++ + + + +VAFG +G + D+ +K+ +L+ T
Sbjct: 619 MPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLLSMGT 678
Query: 638 L-----------HPN----------DSLAMEGPLSRVKSLKKSLRQSFRRI--------- 667
+ P D+ M G + L K +R S++ +
Sbjct: 679 IDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVP 738
Query: 668 ----------------------RKSRVSGKKRAANASSKLQE--------ANAQLAEQAC 697
+S SGK+ ++ SK+ AQ A AC
Sbjct: 739 LELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSA--AC 796
Query: 698 PH-DVEMTPVQRRIEP--RSADDSLSGV-------VRCLYFADTFLR-DGAHHGPTMWAG 746
+ +T + R RS S+S + + LYF D+F R + + P ++ G
Sbjct: 797 MEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDSFARKNDSTISPCLFVG 856
Query: 747 TNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEP 806
T+ G V +L +P A E+R + V VL L + V+ + +D G + P
Sbjct: 857 TSLGMVLIISLNLPLA---DEQRFTEPV-MVLPSGTFLSLKGAVLTFSCMDRMGGLMQPP 912
Query: 807 YEASRD------------------LAQAPDMQGGHA-VLIASEEQFKVFTLPKVSAKTKF 847
YE RD + A G H +I SE+Q KVF+LP +
Sbjct: 913 YEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKVFSLPSQTCLYVH 972
Query: 848 KLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKE 907
+T L V C + CLAC G + + S+P LRP + + +
Sbjct: 973 NITE------TSFILQANVVVMC---SSACLACFCANGHIMIMSLPSLRPMLDVNYLPLT 1023
Query: 908 DISGIASCVFTRHGQGFYLISPSEFERFSLS 938
D+ + FT GQ YL+SP+E +R + S
Sbjct: 1024 DMRIARTFCFTNEGQALYLVSPTEIQRLTYS 1054
>gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
Length = 538
Score = 37.4 bits (85), Expect = 0.076
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 209 TKILIGYSRGLLVIWNQASQCVDHIFLGN-QQLESLCWGRDSSTVVSSHSDGSYAVWSVD 267
T + +G + G +VIW+ ++ + I + + SLCW RD +VS+ +D + W V
Sbjct: 37 TLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVL 96
Query: 268 AG 269
+G
Sbjct: 97 SG 98
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 37.0 bits (84), Expect = 0.099
Identities = 21/55 (38%), Positives = 29/55 (52%)
Query: 956 DATQASYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSP 1010
D +Q+++ S S ++ S +L P S G DPA S P+ PEP EA SP
Sbjct: 1263 DLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSP 1317
>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
Length = 2627
Score = 34.7 bits (78), Expect = 0.49
Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)
Query: 30 EHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFT-GLHRDAATVTQMHFLTGQG 88
+H +P + +AF PE +++A G+ +G++ + G++ T L A++ + F G
Sbjct: 1796 QHTYPKSLNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGG 1855
Query: 89 RLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGAS 131
+ DS + LW A E A P+ GF A+
Sbjct: 1856 VVAVGRLDSMVELW--------AWREGARLAAFPAHHGFVAAA 1890
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 34.3 bits (77), Expect = 0.64
Identities = 22/87 (25%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 32 GFPNQPSALAFDPELRIMAIGTRSGAVKIY----GAPGVEFTGLHRDAATVTQMHFLTGQ 87
G + + L P+ +A+G G+++I+ G V F G H+ A +T + +
Sbjct: 63 GLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNG-HK--AAITTLKYDQLG 119
Query: 88 GRLLSLLDDSSLHLWEIVHHNGCAHLE 114
GRL S D+ + +W++++ +G L+
Sbjct: 120 GRLASGSKDTDIIVWDVINESGLYRLK 146
>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
Length = 1388
Score = 33.5 bits (75), Expect = 1.1
Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 933 ERFSLSARNIT---EPLCSLDINWPRDATQASYRIRESPKLSQANGTPSILLAPQSLDGS 989
ERF+ S + +T +P ++ P +++ + E+ L +A+G IL A S
Sbjct: 213 ERFTGSLQQLTVHPDPRTPEELCDPEESSASG----ETSGLQEADGVAEILEAVTYTQAS 268
Query: 990 PDPAHSMGPDTPEPPEAALSPMSIDSATSADTTLDTTGDVTVEDVKDFLGSSE 1042
P A +TP P + M + + TL+TT ++ GS E
Sbjct: 269 PKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGSGE 321
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 33.1 bits (74), Expect = 1.4
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 6/77 (7%)
Query: 987 DGSPDPAHSMGPDTPEPPEAALSPMSIDSATSADTTLDTTGDVTVEDVKD-----FLGSS 1041
+G+P GP PPE ++ D ++ +TL G + E +K+ F S
Sbjct: 1886 EGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISP 1945
Query: 1042 EESEKNLRNLAEDEAHA 1058
+S +N++ + EDE H+
Sbjct: 1946 AQSHRNIK-ILEDEPHS 1961
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 33.1 bits (74), Expect = 1.4
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 6/77 (7%)
Query: 987 DGSPDPAHSMGPDTPEPPEAALSPMSIDSATSADTTLDTTGDVTVEDVKD-----FLGSS 1041
+G+P GP PPE ++ D ++ +TL G + E +K+ F S
Sbjct: 1669 EGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISP 1728
Query: 1042 EESEKNLRNLAEDEAHA 1058
+S +N++ + EDE H+
Sbjct: 1729 AQSHRNIK-ILEDEPHS 1744
>gi|55743108 ATG16 autophagy related 16-like 2 [Homo sapiens]
Length = 619
Score = 33.1 bits (74), Expect = 1.4
Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 10/64 (15%)
Query: 248 DSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGHFII 307
D S ++ DG+ +W VD G + + GP C A+N + W C SG H +
Sbjct: 559 DRSYALAGSCDGALYIWDVDTGK-------LESRLQGPH-CAAVNAVAW--CYSGSHMVS 608
Query: 308 FSGG 311
G
Sbjct: 609 VDQG 612
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 32.7 bits (73), Expect = 1.9
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 5/54 (9%)
Query: 957 ATQASYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSP 1010
ATQA ++ +P SQ P PQ+ P P P P+PP AA +P
Sbjct: 2 ATQAYTELQAAPPPSQPPQAP-----PQAQPQPPPPPPPAAPQPPQPPTAAATP 50
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 32.7 bits (73), Expect = 1.9
Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 32 GFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGV--EFTGLHRDAATVTQMHFLTGQGR 89
G + + + F P ++A G+R V+I+ P V E T ATV +HF +
Sbjct: 21 GHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQS 79
Query: 90 LLSLLDDSSLHLW 102
++ DD ++ +W
Sbjct: 80 FVTASDDKTVKVW 92
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 32.7 bits (73), Expect = 1.9
Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 32 GFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGV--EFTGLHRDAATVTQMHFLTGQGR 89
G + + + F P ++A G+R V+I+ P V E T ATV +HF +
Sbjct: 59 GHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQS 117
Query: 90 LLSLLDDSSLHLW 102
++ DD ++ +W
Sbjct: 118 FVTASDDKTVKVW 130
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 32.7 bits (73), Expect = 1.9
Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 32 GFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGV--EFTGLHRDAATVTQMHFLTGQGR 89
G + + + F P ++A G+R V+I+ P V E T ATV +HF +
Sbjct: 59 GHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQS 117
Query: 90 LLSLLDDSSLHLW 102
++ DD ++ +W
Sbjct: 118 FVTASDDKTVKVW 130
>gi|46559747 hypothetical protein LOC399947 [Homo sapiens]
Length = 197
Score = 32.7 bits (73), Expect = 1.9
Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 8/84 (9%)
Query: 954 PRDATQASYRIRESPKLSQANGTPSILLAPQ---SLDGSPDPAHSMGPDTPEPPEAALSP 1010
PR QA +E+ Q +P AP SL S GP P PP A SP
Sbjct: 116 PRPGRQAPTHAKETRLERQPRDSP--FCAPSNASSLSSSSPGLPCQGPCAPPPPPPASSP 173
Query: 1011 MSIDSATSADTTLDTTGDVTVEDV 1034
+A+S LDT G+ ++ V
Sbjct: 174 QGAHAASSC---LDTAGEGLLQTV 194
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 32.7 bits (73), Expect = 1.9
Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 219 LLVIWNQASQCVDHIFLG-NQQLESLCWGRDSSTVVSSHSDGSYAVWSVDAG 269
L++IW + G N ++ + W DSS +VS+ D + +W V +G
Sbjct: 64 LIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSG 115
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 32.3 bits (72), Expect = 2.4
Identities = 42/154 (27%), Positives = 58/154 (37%), Gaps = 11/154 (7%)
Query: 902 SCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDAT-QA 960
S ED +G +S FT F SP E L + + P S D PR T Q+
Sbjct: 392 SAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQS 451
Query: 961 SYRIRESPKLSQANGTPSILLAPQSLDGSPDP----AHSMGPDTPEPPE------AALSP 1010
R P ++ P + +PQ L SP P A + G P P + A P
Sbjct: 452 PPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPP 511
Query: 1011 MSIDSATSADTTLDTTGDVTVEDVKDFLGSSEES 1044
+ S + + GD++ LGSS S
Sbjct: 512 RRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAS 545
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 32.3 bits (72), Expect = 2.4
Identities = 42/154 (27%), Positives = 58/154 (37%), Gaps = 11/154 (7%)
Query: 902 SCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDAT-QA 960
S ED +G +S FT F SP E L + + P S D PR T Q+
Sbjct: 442 SAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQS 501
Query: 961 SYRIRESPKLSQANGTPSILLAPQSLDGSPDP----AHSMGPDTPEPPE------AALSP 1010
R P ++ P + +PQ L SP P A + G P P + A P
Sbjct: 502 PPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPP 561
Query: 1011 MSIDSATSADTTLDTTGDVTVEDVKDFLGSSEES 1044
+ S + + GD++ LGSS S
Sbjct: 562 RRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAS 595
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 32.3 bits (72), Expect = 2.4
Identities = 42/154 (27%), Positives = 58/154 (37%), Gaps = 11/154 (7%)
Query: 902 SCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDAT-QA 960
S ED +G +S FT F SP E L + + P S D PR T Q+
Sbjct: 442 SAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQS 501
Query: 961 SYRIRESPKLSQANGTPSILLAPQSLDGSPDP----AHSMGPDTPEPPE------AALSP 1010
R P ++ P + +PQ L SP P A + G P P + A P
Sbjct: 502 PPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPP 561
Query: 1011 MSIDSATSADTTLDTTGDVTVEDVKDFLGSSEES 1044
+ S + + GD++ LGSS S
Sbjct: 562 RRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAS 595
>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
Length = 891
Score = 32.3 bits (72), Expect = 2.4
Identities = 42/154 (27%), Positives = 58/154 (37%), Gaps = 11/154 (7%)
Query: 902 SCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDAT-QA 960
S ED +G +S FT F SP E L + + P S D PR T Q+
Sbjct: 442 SAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQS 501
Query: 961 SYRIRESPKLSQANGTPSILLAPQSLDGSPDP----AHSMGPDTPEPPE------AALSP 1010
R P ++ P + +PQ L SP P A + G P P + A P
Sbjct: 502 PPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPP 561
Query: 1011 MSIDSATSADTTLDTTGDVTVEDVKDFLGSSEES 1044
+ S + + GD++ LGSS S
Sbjct: 562 RRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAS 595
>gi|156139122 CXXC finger 6 [Homo sapiens]
Length = 2136
Score = 32.3 bits (72), Expect = 2.4
Identities = 29/118 (24%), Positives = 45/118 (38%), Gaps = 8/118 (6%)
Query: 945 PLCSLDINWPRDATQASYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPP 1004
P S + P ++ S + E Q N PS L +PQ L SP + EPP
Sbjct: 1911 PTLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPP 1970
Query: 1005 EAALSPMSIDSATSADTTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAIL 1062
P+S D + A+ L + + FL + N+ +A AH ++
Sbjct: 1971 SD--EPLSDDPLSPAEEKLPHIDEYWSDSEHIFL------DANIGGVAIAPAHGSVLI 2020
>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
epsilon, 47kDa [Homo sapiens]
Length = 357
Score = 32.3 bits (72), Expect = 2.4
Identities = 20/67 (29%), Positives = 27/67 (40%)
Query: 376 TPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSSALSWPITGG 435
TP A P P AP SS +A + P + A + + +P AL P GG
Sbjct: 30 TPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALPGPALPGPFPGG 89
Query: 436 RNLAQEP 442
R + P
Sbjct: 90 RVVRLHP 96
>gi|4507103 small nuclear RNA activating complex, polypeptide 2, 45kDa
[Homo sapiens]
Length = 334
Score = 32.3 bits (72), Expect = 2.4
Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 13/103 (12%)
Query: 968 PKLSQANGTPSILLAP-------QSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSAD 1020
PK +QA G P +L AP + S A S P TP+P S S +T D
Sbjct: 142 PKPTQARGKPLLLSAPGGQEDPAPEIPSSAPAAPSSAPRTPDPAPEKPSESSAGPSTEED 201
Query: 1021 TTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILI 1063
+D E + +L S S ++ A + A +L+
Sbjct: 202 FAVD------FEKIYKYLSSVSRSGRSPELSAAESAVVLDLLM 238
>gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific [Homo
sapiens]
Length = 912
Score = 32.0 bits (71), Expect = 3.2
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 12/65 (18%)
Query: 966 ESPKLSQANGTPSILLAPQSLDGSP-DPAHSMGPDTP--------EPPEAALSPMSIDSA 1016
ESP L A +P L PQ+L +P P S P +P E P ++L+P + DSA
Sbjct: 275 ESPSLDSALASP---LDPQALACTPASPPDSQPPASPQDSEALDFETPSSSLAPQTPDSA 331
Query: 1017 TSADT 1021
+++T
Sbjct: 332 LASET 336
>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
Length = 1894
Score = 32.0 bits (71), Expect = 3.2
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 415 AGEQQSPQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLS 474
A +QQ P PV+++ P R+ + PSQ L LT S + P Y S
Sbjct: 1001 APQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDP-YTAS 1059
Query: 475 TAGLFQTDCEHADSLAQAAEDD 496
+ G+ T ++ D AQ + DD
Sbjct: 1060 SRGMLPTALQNQDEDAQGSYDD 1081
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,821,518
Number of Sequences: 37866
Number of extensions: 2142584
Number of successful extensions: 7729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 7520
Number of HSP's gapped (non-prelim): 270
length of query: 1064
length of database: 18,247,518
effective HSP length: 113
effective length of query: 951
effective length of database: 13,968,660
effective search space: 13284195660
effective search space used: 13284195660
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.