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Search of human proteins with 62865654
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62865654 regulator of G-protein signalling 3 isoform 3 [Homo
sapiens]
(602 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865654 regulator of G-protein signalling 3 isoform 3 [Homo ... 1234 0.0
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 1115 0.0
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ... 786 0.0
gi|13384594 protein kinase C, gamma [Homo sapiens] 79 2e-14
gi|4506067 protein kinase C, alpha [Homo sapiens] 76 8e-14
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 72 1e-12
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 72 1e-12
gi|119120915 rhophilin 1 [Homo sapiens] 52 2e-06
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 51 3e-06
gi|154354981 regulating synaptic membrane exocytosis 2 isoform b... 50 8e-06
gi|38570146 synaptotagmin VII [Homo sapiens] 47 5e-05
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 47 7e-05
gi|194018553 solute carrier family 9 isoform 3 regulator 2 isofo... 47 7e-05
gi|71897229 solute carrier family 9 isoform 3 regulator 2 isofor... 47 7e-05
gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo... 46 9e-05
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 46 1e-04
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 46 1e-04
gi|45504376 synaptotagmin VI [Homo sapiens] 46 1e-04
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 45 1e-04
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 45 1e-04
gi|21361472 neural precursor cell expressed, developmentally dow... 44 3e-04
gi|222352086 neural precursor cell expressed, developmentally do... 44 3e-04
gi|45387945 family with sequence similarity 62 (C2 domain contai... 44 3e-04
gi|119120907 par-3 partitioning defective 3 homolog B isoform a ... 44 3e-04
gi|119120903 par-3 partitioning defective 3 homolog B isoform c ... 44 3e-04
gi|119120897 par-3 partitioning defective 3 homolog B isoform b ... 44 3e-04
gi|94536846 synaptotagmin VIII [Homo sapiens] 44 3e-04
gi|211059429 synaptotagmin II [Homo sapiens] 44 4e-04
gi|31543670 synaptotagmin II [Homo sapiens] 44 4e-04
gi|6005997 double C2-like domains, beta [Homo sapiens] 44 4e-04
>gi|62865654 regulator of G-protein signalling 3 isoform 3 [Homo
sapiens]
Length = 602
Score = 1234 bits (3194), Expect = 0.0
Identities = 602/602 (100%), Positives = 602/602 (100%)
Query: 1 MERSLHRVSLGSRRAHPDLSFYLTTFGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDP 60
MERSLHRVSLGSRRAHPDLSFYLTTFGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDP
Sbjct: 1 MERSLHRVSLGSRRAHPDLSFYLTTFGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDP 60
Query: 61 YVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQS 120
YVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQS
Sbjct: 61 YVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQS 120
Query: 121 GLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDT 180
GLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDT
Sbjct: 121 GLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDT 180
Query: 181 ENGKKLKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHW 240
ENGKKLKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHW
Sbjct: 181 ENGKKLKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHW 240
Query: 241 KCVELAHEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTH 300
KCVELAHEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTH
Sbjct: 241 KCVELAHEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTH 300
Query: 301 GVQARPEQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILA 360
GVQARPEQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILA
Sbjct: 301 GVQARPEQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILA 360
Query: 361 PLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVR 420
PLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVR
Sbjct: 361 PLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVR 420
Query: 421 PHATHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAY 480
PHATHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAY
Sbjct: 421 PHATHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAY 480
Query: 481 SDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQE 540
SDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQE
Sbjct: 481 SDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQE 540
Query: 541 QKKRVCWCLSENIAKQQQLAASPPDSKKLHPFGSLQQEMGPVNSTNATQDRSFTSPGQTL 600
QKKRVCWCLSENIAKQQQLAASPPDSKKLHPFGSLQQEMGPVNSTNATQDRSFTSPGQTL
Sbjct: 541 QKKRVCWCLSENIAKQQQLAASPPDSKKLHPFGSLQQEMGPVNSTNATQDRSFTSPGQTL 600
Query: 601 IG 602
IG
Sbjct: 601 IG 602
>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
sapiens]
Length = 1198
Score = 1115 bits (2883), Expect = 0.0
Identities = 549/578 (94%), Positives = 552/578 (95%), Gaps = 4/578 (0%)
Query: 27 GQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRD 86
GQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRD
Sbjct: 139 GQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRD 198
Query: 87 PAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYL 146
PAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYL
Sbjct: 199 PAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYL 258
Query: 147 LGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICCDSP 206
LGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICCDSP
Sbjct: 259 LGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICCDSP 318
Query: 207 VRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQ 266
VRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQ
Sbjct: 319 VRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQ 378
Query: 267 VKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGLLLGG 326
VKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGLLLGG
Sbjct: 379 VKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGLLLGG 438
Query: 327 WERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPS 386
WERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPS
Sbjct: 439 WERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPS 498
Query: 387 KGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSYGTYVTLAPKVLVFPVFVQ 446
KGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSYGTYVTLAPKVLVFPVFVQ
Sbjct: 499 KGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSYGTYVTLAPKVLVFPVFVQ 558
Query: 447 PLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQS 506
PLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQS
Sbjct: 559 PLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQS 618
Query: 507 VKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDS 566
VKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDS
Sbjct: 619 VKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDS 678
Query: 567 KKLHPFGSLQQEM----GPVNSTNATQDRSFTSPGQTL 600
K ++EM G + SPGQ L
Sbjct: 679 KMFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQEL 716
>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
sapiens]
Length = 917
Score = 786 bits (2031), Expect = 0.0
Identities = 388/418 (92%), Positives = 392/418 (93%), Gaps = 4/418 (0%)
Query: 187 KITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELA 246
+ITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELA
Sbjct: 18 QITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELA 77
Query: 247 HEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARP 306
HEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARP
Sbjct: 78 HEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARP 137
Query: 307 EQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGS 366
EQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGS
Sbjct: 138 EQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGS 197
Query: 367 QLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHS 426
QLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHS
Sbjct: 198 QLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHS 257
Query: 427 SYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLF 486
SYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLF
Sbjct: 258 SYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLF 317
Query: 487 TKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVC 546
TKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVC
Sbjct: 318 TKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVC 377
Query: 547 WCLSENIAKQQQLAASPPDSKKLHPFGSLQQEM----GPVNSTNATQDRSFTSPGQTL 600
WCLSENIAKQQQLAASPPDSK ++EM G + SPGQ L
Sbjct: 378 WCLSENIAKQQQLAASPPDSKMFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQEL 435
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/136 (38%), Positives = 75/136 (55%), Gaps = 5/136 (3%)
Query: 27 GQLRLSIDAQDR-VLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQTVPDC 84
G+L+L I A + + + E + LI P G DPYVK+ LIP+ L QKT+TV
Sbjct: 159 GRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKAT 218
Query: 85 RDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWY 144
+P ++E F F ++ D ++RL V VW+ SR + +G MSFGV LL + GWY
Sbjct: 219 LNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSR-NDFMGAMSFGVSELL--KAPVDGWY 275
Query: 145 YLLGEHLGRTKHLKVA 160
LL + G ++ VA
Sbjct: 276 KLLNQEEGEYYNVPVA 291
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 76.3 bits (186), Expect = 8e-14
Identities = 43/127 (33%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 27 GQLRLSIDAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQTVPDCR 85
G++ L + D L + + + K LI P G DPYVK+ LIP+ QKT+T+
Sbjct: 160 GRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTL 219
Query: 86 DPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYY 145
+P ++E F F ++ D +RL V +W+ ++ ++ +G +SFGV L+ SGWY
Sbjct: 220 NPQWNESFTFKLKPSDKDRRLSVEIWD-WDRTTRNDFMGSLSFGVSELM--KMPASGWYK 276
Query: 146 LLGEHLG 152
LL + G
Sbjct: 277 LLNQEEG 283
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 72.4 bits (176), Expect = 1e-12
Identities = 41/127 (32%), Positives = 68/127 (53%), Gaps = 4/127 (3%)
Query: 27 GQLRLSIDAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQTVPDCR 85
G++ + VL++ + + K L+ P G DPYVK+ LIP+ QKT+T+
Sbjct: 160 GRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSL 219
Query: 86 DPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYY 145
+P ++E F F ++E D +RL V +W+ SR + +G +SFG+ L + GW+
Sbjct: 220 NPEWNETFRFQLKESDKDRRLSVEIWDWDLTSR-NDFMGSLSFGISEL--QKASVDGWFK 276
Query: 146 LLGEHLG 152
LL + G
Sbjct: 277 LLSQEEG 283
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 72.4 bits (176), Expect = 1e-12
Identities = 41/127 (32%), Positives = 68/127 (53%), Gaps = 4/127 (3%)
Query: 27 GQLRLSIDAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQTVPDCR 85
G++ + VL++ + + K L+ P G DPYVK+ LIP+ QKT+T+
Sbjct: 160 GRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSL 219
Query: 86 DPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYY 145
+P ++E F F ++E D +RL V +W+ SR + +G +SFG+ L + GW+
Sbjct: 220 NPEWNETFRFQLKESDKDRRLSVEIWDWDLTSR-NDFMGSLSFGISEL--QKASVDGWFK 276
Query: 146 LLGEHLG 152
LL + G
Sbjct: 277 LLSQEEG 283
>gi|119120915 rhophilin 1 [Homo sapiens]
Length = 670
Score = 51.6 bits (122), Expect = 2e-06
Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 18/152 (11%)
Query: 188 ITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAH 247
+ + RG+ GFG T+ DSPV + AV G A AGL++ D ++ +N +P W+ E+
Sbjct: 514 VHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVT 573
Query: 248 EIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPE 307
E+++ G G L+ S + L S ++R R +
Sbjct: 574 ELKAA-----------------GEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQ 616
Query: 308 QRHSCHLVCDS-SDGLLLGGWERYTEVAKRGG 338
+ H C + + L W R + K GG
Sbjct: 617 REHGCKTPASTWASPRPLLNWSRKAQQGKTGG 648
>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
[Homo sapiens]
Length = 1349
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/123 (28%), Positives = 69/123 (56%), Gaps = 6/123 (4%)
Query: 28 QLRLSIDAQDRVLLLHIIEGKGLISKQPGTC-DPYVKISLIPEDSRLRHQKTQTVPDCRD 86
Q++L D L++ I+ K L S++ G +PYVKI +P+ S ++T+TV +
Sbjct: 748 QIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLE 807
Query: 87 PAFHEHFFF-PVQEEDDQKRLL-VTVWNRAS-QSRQSGLIGCMSFGVKSLLTPDKEISGW 143
P +++ F + PV + ++R+L +T+W++A + +S +G + +++ L D+ W
Sbjct: 808 PKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDE--PHW 865
Query: 144 YYL 146
Y L
Sbjct: 866 YKL 868
Score = 35.0 bits (79), Expect = 0.20
Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 15/127 (11%)
Query: 27 GQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCD---PYVKISLIPEDSRLRHQKTQTVPD 83
G +++ + + L + II +GL+ K PG+ PYVK+ L+ + +KT+
Sbjct: 1197 GDIQVGMMDKKGQLEVEIIRARGLVVK-PGSKTLPAPYVKVYLLDNGVCIAKKKTKVARK 1255
Query: 84 CRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEIS-- 141
+P + + F +E K L + VW + + GV +L + E+S
Sbjct: 1256 TLEPLYQQLLSF--EESPQGKVLQIIVWGDYGRMDHKSFM-----GVAQILLDELELSNM 1308
Query: 142 --GWYYL 146
GW+ L
Sbjct: 1309 VIGWFKL 1315
>gi|154354981 regulating synaptic membrane exocytosis 2 isoform b
[Homo sapiens]
Length = 1163
Score = 49.7 bits (117), Expect = 8e-06
Identities = 36/133 (27%), Positives = 73/133 (54%), Gaps = 6/133 (4%)
Query: 18 DLSFYLTTFGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTC-DPYVKISLIPEDSRLRHQ 76
D+ +L+ ++L D L++ I+ K L S++ G +PYVKI +P+ S +
Sbjct: 530 DVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKR 589
Query: 77 KTQTVPDCRDPAFHEHFFF-PVQEEDDQKRLL-VTVWNRAS-QSRQSGLIGCMSFGVKSL 133
+T+TV +P +++ F + PV + ++R+L +T+W++A + +S +G + +++
Sbjct: 590 RTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETA 649
Query: 134 LTPDKEISGWYYL 146
L D+ WY L
Sbjct: 650 LLDDE--PHWYKL 660
Score = 35.0 bits (79), Expect = 0.20
Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 15/127 (11%)
Query: 27 GQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCD---PYVKISLIPEDSRLRHQKTQTVPD 83
G +++ + + L + II +GL+ K PG+ PYVK+ L+ + +KT+
Sbjct: 1011 GDIQVGMMDKKGQLEVEIIRARGLVVK-PGSKTLPAPYVKVYLLDNGVCIAKKKTKVARK 1069
Query: 84 CRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEIS-- 141
+P + + F +E K L + VW + + GV +L + E+S
Sbjct: 1070 TLEPLYQQLLSF--EESPQGKVLQIIVWGDYGRMDHKSFM-----GVAQILLDELELSNM 1122
Query: 142 --GWYYL 146
GW+ L
Sbjct: 1123 VIGWFKL 1129
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/135 (27%), Positives = 70/135 (51%), Gaps = 16/135 (11%)
Query: 27 GQLRLSI--DAQDRVLLLHIIEGKGLISKQ-PGTCDPYVKISLIPEDSRLRHQKTQTVPD 83
G+L LS+ + ++++II+ + L + GT DPYVK+ L+ +D R+ +KT T+
Sbjct: 268 GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKR 327
Query: 84 CRDPAFHEHFFFPVQEED-DQKRLLVTVWNRASQSRQSGLIGCMSFGVKS---------- 132
+P F+E F F + E + +++TV ++ SR + +IG + KS
Sbjct: 328 NLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSR-NDVIGKIYLSWKSGPGEVKHWKD 386
Query: 133 -LLTPDKEISGWYYL 146
+ P + ++ W+ L
Sbjct: 387 MIARPRQPVAQWHQL 401
Score = 30.4 bits (67), Expect = 4.9
Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 28 QLRLSIDAQDRVLLLHIIEGKGLISKQ-PGTCDPYVKISLIPEDSRLRHQKTQTVPDCRD 86
Q + + Q+ L + I++ + L +K GT DP+VKI L+P+ + +T+ +
Sbjct: 140 QFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPD--KKHKLETKVKRKNLN 197
Query: 87 PAFHEHFFF 95
P ++E F F
Sbjct: 198 PHWNETFLF 206
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 46.6 bits (109), Expect = 7e-05
Identities = 31/122 (25%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Query: 27 GQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRD 86
G ++LSI ++ L + ++ K L+++ +PYVK L+P++ + +KT+ R+
Sbjct: 1561 GAVKLSISYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRN 1620
Query: 87 PAFHEHFFFPVQEEDD--QKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWY 144
P F+E + ++ Q+ L ++V + A R++ +G ++ +K KE WY
Sbjct: 1621 PTFNEMLVYSGYSKETLRQRELQLSVLS-AESLRENFFLGGVTLPLKD-FNLSKETVKWY 1678
Query: 145 YL 146
L
Sbjct: 1679 QL 1680
>gi|194018553 solute carrier family 9 isoform 3 regulator 2 isoform
a [Homo sapiens]
Length = 337
Score = 46.6 bits (109), Expect = 7e-05
Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 19/122 (15%)
Query: 158 KVARRRLRPLRDPLLRMP-----GGGDTENGKK-----LKITIPR------GKDGFGFTI 201
++A+R L P DP P G +E GKK L+ PR G G+GF +
Sbjct: 106 EMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNL 165
Query: 202 CCDSP---VRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIIL 258
D +++VD G PA R+GL+ D ++++N + VE + E+ I++ E L
Sbjct: 166 HSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARL 225
Query: 259 LV 260
LV
Sbjct: 226 LV 227
>gi|71897229 solute carrier family 9 isoform 3 regulator 2 isoform b
[Homo sapiens]
Length = 326
Score = 46.6 bits (109), Expect = 7e-05
Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 19/122 (15%)
Query: 158 KVARRRLRPLRDPLLRMP-----GGGDTENGKK-----LKITIPR------GKDGFGFTI 201
++A+R L P DP P G +E GKK L+ PR G G+GF +
Sbjct: 106 EMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNL 165
Query: 202 CCDSP---VRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIIL 258
D +++VD G PA R+GL+ D ++++N + VE + E+ I++ E L
Sbjct: 166 HSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARL 225
Query: 259 LV 260
LV
Sbjct: 226 LV 227
>gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo
sapiens]
Length = 1544
Score = 46.2 bits (108), Expect = 9e-05
Identities = 24/64 (37%), Positives = 38/64 (59%)
Query: 188 ITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAH 247
+ I + +GFG T+ D+PV VQ+V G A RAG+Q D ++++N V H +E+
Sbjct: 73 VIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVK 132
Query: 248 EIRS 251
I+S
Sbjct: 133 LIKS 136
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Query: 24 TTFGQLRLSI--DAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQT 80
TT G L S+ D + L II+ KGL G DPYVK+ L+P S+ +T+T
Sbjct: 391 TTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKT 450
Query: 81 VPDCRDPAFHEHF-FFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSL 133
+ + R+P ++E + + +ED Q++ L + + IG F +K L
Sbjct: 451 LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 504
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 11/106 (10%)
Query: 56 GTCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLL-VTVWNRA 114
G DP+VK+ L P+ + KTQ +P F+E FF+ ++ D K+ L ++VW+
Sbjct: 584 GYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD 643
Query: 115 SQSRQSGLIGC----------MSFGVKSLLTPDKEISGWYYLLGEH 150
+ GC + + L DK+I W+ L E+
Sbjct: 644 IGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN 689
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Query: 24 TTFGQLRLSI--DAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQT 80
TT G L S+ D + L II+ KGL G DPYVK+ L+P S+ +T+T
Sbjct: 387 TTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKT 446
Query: 81 VPDCRDPAFHEHF-FFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSL 133
+ + R+P ++E + + +ED Q++ L + + IG F +K L
Sbjct: 447 LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 500
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 11/106 (10%)
Query: 56 GTCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLL-VTVWNRA 114
G DP+VK+ L P+ + KTQ +P F+E FF+ ++ D K+ L ++VW+
Sbjct: 580 GYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD 639
Query: 115 SQSRQSGLIGC----------MSFGVKSLLTPDKEISGWYYLLGEH 150
+ GC + + L DK+I W+ L E+
Sbjct: 640 IGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN 685
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 21/137 (15%)
Query: 22 YLTTFGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTV 81
YL T G+L L++ + + I G DPYVK+SL+ + RL+ +KT
Sbjct: 286 YLPTAGRLTLTVIKCRNLKAMDIT----------GYSDPYVKVSLLCDGRRLKKKKTTIK 335
Query: 82 PDCRDPAFHEHFFFPVQEED-DQKRLLVTV--WNRASQSRQSGL--IGCMSFGV------ 130
+ +P ++E F + E+ DQ LL++V ++R + G+ +G + G+
Sbjct: 336 KNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWN 395
Query: 131 KSLLTPDKEISGWYYLL 147
+ L P K I+ W+ L+
Sbjct: 396 EMLAYPRKPIAHWHSLV 412
Score = 38.9 bits (89), Expect = 0.014
Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 31 LSIDAQDRVLLLHIIEGKGLISKQ-PGTCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAF 89
L D + L++ I++ L +K G+ DPYVKI L+P+ R +T+ +P F
Sbjct: 152 LRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPD--RKCKLQTRVHRKTLNPTF 209
Query: 90 HEHFFFPVQEEDDQKRLL 107
E+F FPV E+ R L
Sbjct: 210 DENFHFPVPYEELADRKL 227
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/108 (28%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 27 GQLRLSIDAQDRV--LLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDC 84
G+L S++ + LL+ +I+ + L + TC P VK+ L+P++ R KT+
Sbjct: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSE-TCSPLVKLYLLPDERRFLQSKTKRKTS- 206
Query: 85 RDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKS 132
+P F EHF F V + +R+L + R+ L+G + F +K+
Sbjct: 207 -NPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
Score = 35.0 bits (79), Expect = 0.20
Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 10/130 (7%)
Query: 26 FGQLRLSIDAQDRV--LLLHIIEGKGL-ISKQPGTCDPYVKISLIPEDSRLRHQKTQTVP 82
FG L+ + D + L + ++ KGL + + G +VK+SL+ + ++ +KT V
Sbjct: 279 FGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVL 338
Query: 83 DCRDPAFHEHFFFPVQ--EEDDQKRLLVTVWN-RASQSRQSGLIGCMSFGVKSLLTPDKE 139
+P ++E F F E D L V N +S+Q G + + + T +E
Sbjct: 339 GSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPY----MYTRGRE 394
Query: 140 ISGWYYLLGE 149
+ W +L +
Sbjct: 395 LEHWDEMLSK 404
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/108 (28%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 27 GQLRLSIDAQDRV--LLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDC 84
G+L S++ + LL+ +I+ + L + TC P VK+ L+P++ R KT+
Sbjct: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSE-TCSPLVKLYLLPDERRFLQSKTKRKTS- 206
Query: 85 RDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKS 132
+P F EHF F V + +R+L + R+ L+G + F +K+
Sbjct: 207 -NPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
Score = 35.0 bits (79), Expect = 0.20
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 4/111 (3%)
Query: 26 FGQLRLSIDAQDRV--LLLHIIEGKGL-ISKQPGTCDPYVKISLIPEDSRLRHQKTQTVP 82
FG L+ + D + L + ++ KGL + + G +VK+SL+ + ++ +KT V
Sbjct: 279 FGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVL 338
Query: 83 DCRDPAFHEHFFFPVQ-EEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKS 132
+P ++E F F E D L +TV +Q+ + F + S
Sbjct: 339 GSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKQATTVELFLFHLTS 389
>gi|21361472 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 3 [Homo sapiens]
Length = 955
Score = 44.3 bits (103), Expect = 3e-04
Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 7/152 (4%)
Query: 34 DAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISL--IPEDSRLRHQKTQTVPDCRDPAFH 90
+ + R+L + ++ G L K G DPYVK+SL E+ L +T+T+ +P ++
Sbjct: 16 EGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWN 75
Query: 91 EHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEH 150
E F+F V + RLL V++ +R +G + + L T D + Y
Sbjct: 76 EEFYFRVNPSN--HRLLFEVFDENRLTRDD-FLGQVDVPLSHLPTEDPTMERPYTFKDFL 132
Query: 151 LGRTKHLKVARRRLRPLRDPLLRMPGGGDTEN 182
L H + LR L+ + GG D EN
Sbjct: 133 LRPRSHKSRVKGFLR-LKMAYMPKNGGQDEEN 163
>gi|222352086 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 1 [Homo sapiens]
Length = 975
Score = 44.3 bits (103), Expect = 3e-04
Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 7/152 (4%)
Query: 34 DAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISL--IPEDSRLRHQKTQTVPDCRDPAFH 90
+ + R+L + ++ G L K G DPYVK+SL E+ L +T+T+ +P ++
Sbjct: 16 EGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWN 75
Query: 91 EHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEH 150
E F+F V + RLL V++ +R +G + + L T D + Y
Sbjct: 76 EEFYFRVNPSN--HRLLFEVFDENRLTRDD-FLGQVDVPLSHLPTEDPTMERPYTFKDFL 132
Query: 151 LGRTKHLKVARRRLRPLRDPLLRMPGGGDTEN 182
L H + LR L+ + GG D EN
Sbjct: 133 LRPRSHKSRVKGFLR-LKMAYMPKNGGQDEEN 163
>gi|45387945 family with sequence similarity 62 (C2 domain
containing) member B [Homo sapiens]
Length = 893
Score = 44.3 bits (103), Expect = 3e-04
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 8/121 (6%)
Query: 27 GQLRLSI--DAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDC 84
GQ++L+I +Q L++ + + LI+ DPYV++ L+P+ R +KT
Sbjct: 760 GQIQLTIRHSSQRNKLIVVVHACRNLIAFSEDGSDPYVRMYLLPDKRRSGRRKTHVSKKT 819
Query: 85 RDPAFHEHFFFPVQEEDDQKRLL-VTVWNRAS-QSRQSGLIGCMSFGVKSLLTPDKEISG 142
+P F + F F V + Q+R L V V N S+ GL+G V L ++ G
Sbjct: 820 LNPVFDQSFDFSVSLPEVQRRTLDVAVKNSGGFLSKDKGLLG----KVLVALASEELAKG 875
Query: 143 W 143
W
Sbjct: 876 W 876
>gi|119120907 par-3 partitioning defective 3 homolog B isoform a
[Homo sapiens]
Length = 1104
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 8/109 (7%)
Query: 151 LGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICC------- 203
L + K +V R +P L + G G +N KK+KI + +G +G GFT+
Sbjct: 347 LQQNKSPRVPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHG 406
Query: 204 DSPVRVQAVDSGGPAERAG-LQQLDTVLQLNERPVEHWKCVELAHEIRS 251
P+ V+ + G A + G LQ D +L++N R V EL +RS
Sbjct: 407 PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRS 455
>gi|119120903 par-3 partitioning defective 3 homolog B isoform c
[Homo sapiens]
Length = 1136
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 8/109 (7%)
Query: 151 LGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICC------- 203
L + K +V R +P L + G G +N KK+KI + +G +G GFT+
Sbjct: 347 LQQNKSPRVPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHG 406
Query: 204 DSPVRVQAVDSGGPAERAG-LQQLDTVLQLNERPVEHWKCVELAHEIRS 251
P+ V+ + G A + G LQ D +L++N R V EL +RS
Sbjct: 407 PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRS 455
>gi|119120897 par-3 partitioning defective 3 homolog B isoform b
[Homo sapiens]
Length = 1143
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 8/109 (7%)
Query: 151 LGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICC------- 203
L + K +V R +P L + G G +N KK+KI + +G +G GFT+
Sbjct: 347 LQQNKSPRVPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHG 406
Query: 204 DSPVRVQAVDSGGPAERAG-LQQLDTVLQLNERPVEHWKCVELAHEIRS 251
P+ V+ + G A + G LQ D +L++N R V EL +RS
Sbjct: 407 PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRS 455
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 44.3 bits (103), Expect = 3e-04
Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 12/131 (9%)
Query: 40 LLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQE 99
L + ++E +GL +PG +PYVK+ L+ + + +KT T P F+E F F V
Sbjct: 262 LTVVVLEARGL---RPGLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPF 318
Query: 100 EDDQK-RLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLK 158
Q L++ VW+R+ R +G + G ++ P + W + L +
Sbjct: 319 SQVQNVDLVLAVWDRSLPLRTEP-VGKVHLGARASGQP---LQHW----ADMLAHARRPI 370
Query: 159 VARRRLRPLRD 169
R LRP R+
Sbjct: 371 AQRHPLRPARE 381
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 43.9 bits (102), Expect = 4e-04
Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 17/133 (12%)
Query: 40 LLLHIIEGKGLISKQPG-TCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQ 98
L + I+E K L G DPYVKI L+ RL+ +KT +P F+E F F +
Sbjct: 287 LTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIP 346
Query: 99 EEDDQK-RLLVTV--WNRASQSRQSG--LIGCMSFGVK------SLLTPDKEISGWYYLL 147
E QK +++VTV +++ ++ G +G + G + L P + I+ W+ L
Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 406
Query: 148 GEH-----LGRTK 155
E LG+ K
Sbjct: 407 PEEEVDALLGKNK 419
Score = 36.6 bits (83), Expect = 0.068
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 28 QLRLSIDAQDRVLLLHIIEGKGLIS-KQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRD 86
Q L D Q L + +++ L + GT DPYVK+ L+P+ + + +T+ +
Sbjct: 144 QFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD--KKKKYETKVHRKTLN 201
Query: 87 PAFHEHFFFPV-QEEDDQKRLLVTVWN 112
PAF+E F F V +E K L++ +++
Sbjct: 202 PAFNETFTFKVPYQELGGKTLVMAIYD 228
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 43.9 bits (102), Expect = 4e-04
Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 17/133 (12%)
Query: 40 LLLHIIEGKGLISKQPG-TCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQ 98
L + I+E K L G DPYVKI L+ RL+ +KT +P F+E F F +
Sbjct: 287 LTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIP 346
Query: 99 EEDDQK-RLLVTV--WNRASQSRQSG--LIGCMSFGVK------SLLTPDKEISGWYYLL 147
E QK +++VTV +++ ++ G +G + G + L P + I+ W+ L
Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 406
Query: 148 GEH-----LGRTK 155
E LG+ K
Sbjct: 407 PEEEVDALLGKNK 419
Score = 36.6 bits (83), Expect = 0.068
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 28 QLRLSIDAQDRVLLLHIIEGKGLIS-KQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRD 86
Q L D Q L + +++ L + GT DPYVK+ L+P+ + + +T+ +
Sbjct: 144 QFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD--KKKKYETKVHRKTLN 201
Query: 87 PAFHEHFFFPV-QEEDDQKRLLVTVWN 112
PAF+E F F V +E K L++ +++
Sbjct: 202 PAFNETFTFKVPYQELGGKTLVMAIYD 228
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 14/134 (10%)
Query: 29 LRLSIDAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQTVPDCRDP 87
+ L +Q + LL+ I+ L + G DPYVK L P+ + KT +P
Sbjct: 272 ISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNP 331
Query: 88 AFHEHFFFPVQEED-DQKRLLVTVWNRASQSRQSGLIGCMSFGVKS-----------LLT 135
F+E F + ++ D +K L VTVW+ + + IG + G+ + L
Sbjct: 332 EFNEEFCYEIKHGDLAKKSLEVTVWD-YDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKN 390
Query: 136 PDKEISGWYYLLGE 149
DK I W+ L E
Sbjct: 391 KDKRIERWHTLTSE 404
Score = 38.5 bits (88), Expect = 0.018
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
Query: 24 TTFGQLRLSI--DAQDRVLLLHIIEGKGLISKQP-GTCDPYVKISLIPEDSRLRHQKTQT 80
T G L S+ D ++ L I + KGL G DPYVK+ L+P S+ +T+T
Sbjct: 125 TALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKT 184
Query: 81 VPDCRDPAFHEHF-FFPVQEEDDQKRLL 107
+ + +P ++E ++ + +ED ++ L
Sbjct: 185 LRNTLNPTWNETLTYYGITDEDMIRKTL 212
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,124,772
Number of Sequences: 37866
Number of extensions: 1297473
Number of successful extensions: 3003
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 2801
Number of HSP's gapped (non-prelim): 259
length of query: 602
length of database: 18,247,518
effective HSP length: 108
effective length of query: 494
effective length of database: 14,157,990
effective search space: 6994047060
effective search space used: 6994047060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.