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Search of human proteins with 62241022
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
[Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [... 737 0.0
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H... 737 0.0
gi|8922886 DDX19-like protein [Homo sapiens] 730 0.0
gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [... 695 0.0
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap... 538 e-153
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 252 4e-67
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 251 7e-67
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 237 1e-62
gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 198 6e-51
gi|18375623 HLA-B associated transcript 1 [Homo sapiens] 198 6e-51
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 196 4e-50
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 189 4e-48
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi... 186 4e-47
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 162 6e-40
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 151 8e-37
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 151 8e-37
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 149 3e-36
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 148 7e-36
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 148 7e-36
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 142 4e-34
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 142 6e-34
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 133 2e-31
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 133 2e-31
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 133 2e-31
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 133 2e-31
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 133 3e-31
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 132 4e-31
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 132 4e-31
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 132 4e-31
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 130 1e-30
>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
[Homo sapiens]
Length = 370
Score = 737 bits (1902), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS
Sbjct: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 120
PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK
Sbjct: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 120
Query: 121 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 180
FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV
Sbjct: 121 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 180
Query: 181 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 240
PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL
Sbjct: 181 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 240
Query: 241 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 300
AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD
Sbjct: 241 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 300
Query: 301 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 360
LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD
Sbjct: 301 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 360
Query: 361 DLDEIEKIAN 370
DLDEIEKIAN
Sbjct: 361 DLDEIEKIAN 370
>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
sapiens]
Length = 479
Score = 737 bits (1902), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS
Sbjct: 110 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 169
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 120
PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK
Sbjct: 170 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 229
Query: 121 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 180
FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV
Sbjct: 230 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 289
Query: 181 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 240
PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL
Sbjct: 290 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 349
Query: 241 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 300
AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD
Sbjct: 350 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 409
Query: 301 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 360
LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD
Sbjct: 410 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 469
Query: 361 DLDEIEKIAN 370
DLDEIEKIAN
Sbjct: 470 DLDEIEKIAN 479
>gi|8922886 DDX19-like protein [Homo sapiens]
Length = 478
Score = 730 bits (1885), Expect = 0.0
Identities = 365/370 (98%), Positives = 370/370 (100%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
MGFNRPSKIQENALP+MLAEPPQNLIAQSQSGTGKTAAFVLAMLS+VEP+++YPQCLCLS
Sbjct: 109 MGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPSDRYPQCLCLS 168
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 120
PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK
Sbjct: 169 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 228
Query: 121 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 180
FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV
Sbjct: 229 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 288
Query: 181 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 240
PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL
Sbjct: 289 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 348
Query: 241 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 300
AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD
Sbjct: 349 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 408
Query: 301 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 360
LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD
Sbjct: 409 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 468
Query: 361 DLDEIEKIAN 370
DLDEIEKIAN
Sbjct: 469 DLDEIEKIAN 478
>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
[Homo sapiens]
Length = 448
Score = 695 bits (1794), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 22 PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP 81
PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP
Sbjct: 100 PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP 159
Query: 82 ELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIAT 141
ELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIAT
Sbjct: 160 ELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIAT 219
Query: 142 QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQY 201
QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQY
Sbjct: 220 QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQY 279
Query: 202 YVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVE 261
YVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVE
Sbjct: 280 YVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVE 339
Query: 262 QRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT 321
QRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT
Sbjct: 340 QRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT 399
Query: 322 GRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 370
GRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 400 GRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 448
>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
sapiens]
Length = 483
Score = 538 bits (1385), Expect = e-153
Identities = 256/368 (69%), Positives = 315/368 (85%), Gaps = 1/368 (0%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
MGFNRPSKIQE ALP+MLA PPQNLIAQSQSGTGKTAAFVLAMLS+V +PQCLCL+
Sbjct: 115 MGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLA 174
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 120
PTYELALQTG+V+EQMGKF ++++ YA+RGN++ RG I++QI+IGTPGTVLDWC KLK
Sbjct: 175 PTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLK 234
Query: 121 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 180
ID KI+VFVLDEADVMI TQG D SIRIQR LP CQMLLFSATFEDSVW FA++++
Sbjct: 235 LIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERII 294
Query: 181 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 240
PDPNVIKL++EE TL+ I+QYYVLC R +K+QALCN+YG+ITI QA+IFC TR+ A WL
Sbjct: 295 PDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWL 354
Query: 241 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 300
E+ ++GHQV+LLSGE+ VEQRA++I+RFR+GKEKVL+TTNVCARGIDV+QV++V+NFD
Sbjct: 355 TVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFD 414
Query: 301 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 360
LPV + PD ETYLHRIGRTGRFGK+GLA NM++ +++ +IQ+HFN I++L+ +
Sbjct: 415 LPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLM-KIQDHFNSSIKQLNAE 473
Query: 361 DLDEIEKI 368
D+DEIEKI
Sbjct: 474 DMDEIEKI 481
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 252 bits (643), Expect = 4e-67
Identities = 148/369 (40%), Positives = 226/369 (61%), Gaps = 18/369 (4%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
GF +PS IQ+ A+ + ++IAQ+QSGTGKTA F +++L Q+E K Q L L+P
Sbjct: 52 GFEKPSAIQQRAIIPCIKG--YDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAP 109
Query: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRG-----NKLERGQKISEQIVIGTPGTVLDWC 116
T ELA Q KVI +G + +A G N++++ Q + IV+GTPG V D
Sbjct: 110 TRELAQQIQKVILALGDYMGAT--CHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDML 167
Query: 117 SKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFA 176
++ +++ PK IK+FVLDEAD M++ +G +DQ I + L + Q++L SAT V +
Sbjct: 168 NR-RYLSPKWIKMFVLDEADEMLS-RGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVT 225
Query: 177 QKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT 236
+K + DP I +K+EE TL+ IKQ+Y+ + K LC+LY +TI QA+IF +TR+
Sbjct: 226 KKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRK 285
Query: 237 ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVV 296
WL ++ V+ L G+M ++R ++ FR G +VL+TT++ ARGIDV+QVS+V
Sbjct: 286 VDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLV 345
Query: 297 INFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIER 356
IN+DLP ++ E Y+HRIGR GRFG++G+A+N V ++ IL I+ +N +E
Sbjct: 346 INYDLPTNR------ENYIHRIGRGGRFGRKGVAINFV-TEEDKRILRDIETFYNTTVEE 398
Query: 357 LDTDDLDEI 365
+ + D I
Sbjct: 399 MPMNVADLI 407
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 251 bits (641), Expect = 7e-67
Identities = 148/368 (40%), Positives = 223/368 (60%), Gaps = 16/368 (4%)
Query: 2 GFNRPSKIQENA-LPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
GF +PS IQ+ A LP + ++IAQ+QSGTGKTA F +++L Q+E K Q L L+
Sbjct: 51 GFEKPSAIQQRAILPCIKG---YDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLA 107
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCS 117
PT ELA Q KV+ +G + A N QK+ + I++GTPG V D +
Sbjct: 108 PTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLN 167
Query: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177
+ +++ PK IK+FVLDEAD M++ +G +DQ I + L N Q++L SAT V + +
Sbjct: 168 R-RYLSPKYIKMFVLDEADEMLS-RGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTK 225
Query: 178 KVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTA 237
K + DP I +K+EE TL+ I+Q+Y+ + K LC+LY +TI QA+IF +TR+
Sbjct: 226 KFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKV 285
Query: 238 SWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVI 297
WL ++ V+ + G+M ++R ++ FR G +VL+TT++ ARGIDV+QVS+VI
Sbjct: 286 DWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI 345
Query: 298 NFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERL 357
N+DLP ++ E Y+HRIGR GRFG++G+A+NMV ++ L I+ +N IE +
Sbjct: 346 NYDLPTNR------ENYIHRIGRGGRFGRKGVAINMV-TEEDKRTLRDIETFYNTSIEEM 398
Query: 358 DTDDLDEI 365
+ D I
Sbjct: 399 PLNVADLI 406
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 237 bits (605), Expect = 1e-62
Identities = 137/371 (36%), Positives = 226/371 (60%), Gaps = 23/371 (6%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
GF +PS IQ+ A+ ++ +++IAQSQSGTGKTA F +++L ++ + Q L L+P
Sbjct: 57 GFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAP 114
Query: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLERGQKISEQIVIGTPGTVLD 114
T ELA+Q K + +G Y ++ + G KL+ GQ +V GTPG V D
Sbjct: 115 TRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDYGQ----HVVAGTPGRVFD 169
Query: 115 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 174
+ + + + IK+ VLDEAD M+ +G ++Q + R LP Q++L SAT + +
Sbjct: 170 MIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPHEILE 227
Query: 175 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 234
K + DP I +KR+E TL+ IKQ++V + KF LC+LY +TI QA+IFC+T+
Sbjct: 228 MTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTK 287
Query: 235 KTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS 294
+ WL ++ + V+ + G+M ++R ++++ FR G +VL++T+V ARG+DV QVS
Sbjct: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVS 347
Query: 295 VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKI 354
++IN+DLP ++ E Y+HRIGR+GR+G++G+A+N V + IL I+++++ +I
Sbjct: 348 LIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRDIEQYYSTQI 400
Query: 355 ERLDTDDLDEI 365
+ + + D I
Sbjct: 401 DEMPMNVADLI 411
>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 198 bits (504), Expect = 6e-51
Identities = 122/367 (33%), Positives = 200/367 (54%), Gaps = 16/367 (4%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
GF PS++Q +P + +++ Q++SG GKTA FVLA L Q+EP L +
Sbjct: 64 GFEHPSEVQHECIPQAILG--MDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCH 121
Query: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ----IVIGTPGTVLDWCS 117
T ELA Q K E+ K+ P +K+A G +++ +++ ++ IV+GTPG +L +
Sbjct: 122 TRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILA-LA 180
Query: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177
+ K ++ K IK F+LDE D M+ + I RM P Q+++FSAT + +
Sbjct: 181 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR 240
Query: 178 KVVPDPNVIKLKREEE-TLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT 236
K + DP I + E + TL ++QYYV +EK + L +L + Q +IF + +
Sbjct: 241 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQR 299
Query: 237 ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVV 296
LA L ++ + M E+R + ++F++ + ++LV TN+ RG+D+E+V++
Sbjct: 300 CIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIA 359
Query: 297 INFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIER 356
N+D+P D D TYLHR+ R GRFG +GLA+ V ++ ILN +Q+ F I
Sbjct: 360 FNYDMPEDSD------TYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISE 413
Query: 357 LDTDDLD 363
L D++D
Sbjct: 414 L-PDEID 419
>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 198 bits (504), Expect = 6e-51
Identities = 122/367 (33%), Positives = 200/367 (54%), Gaps = 16/367 (4%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
GF PS++Q +P + +++ Q++SG GKTA FVLA L Q+EP L +
Sbjct: 64 GFEHPSEVQHECIPQAILG--MDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCH 121
Query: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ----IVIGTPGTVLDWCS 117
T ELA Q K E+ K+ P +K+A G +++ +++ ++ IV+GTPG +L +
Sbjct: 122 TRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILA-LA 180
Query: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177
+ K ++ K IK F+LDE D M+ + I RM P Q+++FSAT + +
Sbjct: 181 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR 240
Query: 178 KVVPDPNVIKLKREEE-TLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT 236
K + DP I + E + TL ++QYYV +EK + L +L + Q +IF + +
Sbjct: 241 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQR 299
Query: 237 ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVV 296
LA L ++ + M E+R + ++F++ + ++LV TN+ RG+D+E+V++
Sbjct: 300 CIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIA 359
Query: 297 INFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIER 356
N+D+P D D TYLHR+ R GRFG +GLA+ V ++ ILN +Q+ F I
Sbjct: 360 FNYDMPEDSD------TYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISE 413
Query: 357 LDTDDLD 363
L D++D
Sbjct: 414 L-PDEID 419
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 196 bits (497), Expect = 4e-50
Identities = 117/361 (32%), Positives = 192/361 (53%), Gaps = 15/361 (4%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
GF PS++Q +P + +++ Q++SG GKTA FVLA L Q+EP N L +
Sbjct: 63 GFEHPSEVQHECIPQAILG--MDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCH 120
Query: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ----IVIGTPGTVLDWCS 117
T ELA Q K E+ K+ P +K++ G +++ +++ ++ +V+GTPG +L
Sbjct: 121 TRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVR 180
Query: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177
F K +K FVLDE D M+ + I R+ P Q ++FSAT + +
Sbjct: 181 NRSF-SLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCR 239
Query: 178 KVVPDPNVIKLKREEE-TLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT 236
K + DP + + E + TL ++QYYV EK + L +L + Q +IF + +
Sbjct: 240 KFMQDPMEVFVDDETKLTLHGLQQYYVKLKD-SEKNRKLFDLLDVLEFNQVIIFVKSVQR 298
Query: 237 ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVV 296
LA L ++ + M E+R + ++F++ + ++LV TN+ RG+D+E+V++V
Sbjct: 299 CMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIV 358
Query: 297 INFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIER 356
N+D+P D D TYLHR+ R GRFG +GLA+ V ++ ILN +Q+ F +
Sbjct: 359 FNYDMPEDSD------TYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAE 412
Query: 357 L 357
L
Sbjct: 413 L 413
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 189 bits (479), Expect = 4e-48
Identities = 127/364 (34%), Positives = 204/364 (56%), Gaps = 18/364 (4%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
MG+ +PS IQE ++P+ L+ ++++A++++GTGK+ A+++ +L +++ Q + +
Sbjct: 114 MGWEKPSPIQEESIPIALSG--RDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIV 171
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG-QKISE--QIVIGTPGTVLDWCS 117
PT ELALQ ++ Q+ K K+ G L ++ + +VI TPG +LD
Sbjct: 172 PTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIK 231
Query: 118 K-LKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFA 176
K + +D +++ VLDEAD +++ Q I LP+N Q+LL+SATF SV KF
Sbjct: 232 KGVAKVD--HVQMIVLDEADKLLSQDFVQIME-DIILTLPKNRQILLYSATFPLSVQKFM 288
Query: 177 QKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT 236
+ P I L EE TL + QYY + R +K L L+ + I Q++IFC++ +
Sbjct: 289 NSHLQKPYEINLM-EELTLKGVTQYYAYVTER-QKVHCLNTLFSRLQINQSIIFCNSSQR 346
Query: 237 ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVV 296
LA ++S+ G+ + +M E R V FR G + LV T++ RGID++ V+VV
Sbjct: 347 VELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVV 406
Query: 297 INFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIER 356
INFD P ETYLHRIGR+GRFG GLA+N++ N L I+E +I+
Sbjct: 407 INFDFP------KLAETYLHRIGRSGRFGHLGLAINLITYDDRFN-LKSIEEQLGTEIKP 459
Query: 357 LDTD 360
+ ++
Sbjct: 460 IPSN 463
>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
sapiens]
Length = 824
Score = 186 bits (471), Expect = 4e-47
Identities = 122/359 (33%), Positives = 189/359 (52%), Gaps = 18/359 (5%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
GF RPS +Q A+PL +LI Q++SGTGKT F L + N Q L L+P
Sbjct: 81 GFERPSPVQLKAIPL--GRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAP 138
Query: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ--IVIGTPGTVLDWCSKL 119
T E+A+Q VI +G L+ + G L + + ++ I +G+PG + +L
Sbjct: 139 TREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLI-EL 197
Query: 120 KFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKV 179
+++P I++F+LDEAD ++ Q+Q I LP + QML SAT+ + + K
Sbjct: 198 DYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKY 257
Query: 180 VPDPNVIKLKREEETLDTIKQYYVLCSSR-------DEKFQALCNLYGAITIAQAMIFCH 232
+ DP ++L + +L +KQYY + +S +EK Q L L+ I QA++F +
Sbjct: 258 MRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSN 317
Query: 233 TRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQ 292
A LA LS +G +SG M QR + + + +VL++T++ +RGID E+
Sbjct: 318 LHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEK 377
Query: 293 VSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFN 351
V++V+N D+P+D ETY+HRIGR GRFG GL V N++ RI + N
Sbjct: 378 VNLVVNLDVPLDW------ETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCN 430
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 162 bits (409), Expect = 6e-40
Identities = 108/368 (29%), Positives = 192/368 (52%), Gaps = 16/368 (4%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
+G+ +P+KIQ A+PL L +++I +++G+GKT AF L +L+ + + L L+
Sbjct: 42 LGWTKPTKIQIEAIPLALQG--RDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLT 99
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRG-NKLERGQKISEQ--IVIGTPGTVLDWCS 117
PT ELA Q + E +G ++ A V G + + + ++++ I+I TPG ++D
Sbjct: 100 PTRELAFQISEQFEALGSSIG-VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
Query: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177
K + + +K V+DEAD I + + +I +++PR+ + LFSAT V K +
Sbjct: 159 NTKGFNLRALKYLVMDEAD-RILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQR 217
Query: 178 KVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTA 237
+ +P + + +T++ ++QYY+ S+ K L + + MIFC T
Sbjct: 218 AALKNPVKCAVSSKYQTVEKLQQYYIFIPSKF-KDTYLVYILNELAGNSFMIFCSTCNNT 276
Query: 238 SWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVI 297
A L G L G+M +R + +F+ +L+ T+V +RG+D+ V VV+
Sbjct: 277 QRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVV 336
Query: 298 NFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERL 357
NFD+P ++ Y+HR+GRT R G+ G A+ V +++ + + RI+ KK+
Sbjct: 337 NFDIPT------HSKDYIHRVGRTARAGRSGKAITFV-TQYDVELFQRIEHLIGKKLPGF 389
Query: 358 DTDDLDEI 365
T D DE+
Sbjct: 390 PTQD-DEV 396
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 151 bits (382), Expect = 8e-37
Identities = 119/367 (32%), Positives = 185/367 (50%), Gaps = 41/367 (11%)
Query: 3 FNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEP------------- 49
+ RP+ +Q++A+P++ + ++L+A +Q+G+GKTAAF+L +LSQ+
Sbjct: 198 YTRPTPVQKHAIPIIKGK--RDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKEN 255
Query: 50 -----ANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-- 102
+YP L L+PT ELA+Q + E+ KF ++ V + GQ+I +
Sbjct: 256 GRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE 312
Query: 103 ---QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRI---QRMLP 156
+++ TPG ++D + K I K VLDEAD M+ G + Q RI M P
Sbjct: 313 RGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRML-DMGFEPQIRRIVEQDTMPP 370
Query: 157 RNCQ-MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQAL 215
+ + ++FSATF + A+ + + + + R T + I Q V D++ L
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
Query: 216 CNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKE 275
L + + ++F T+K A L L EG+ + G+ R + +FR GK
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
Query: 276 KVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 335
+LV T V ARG+D+ V VINFDLP D E Y+HRIGRTGR G GLA + +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFN 544
Query: 336 SKHSMNI 342
K +MNI
Sbjct: 545 EK-NMNI 550
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 151 bits (382), Expect = 8e-37
Identities = 119/367 (32%), Positives = 185/367 (50%), Gaps = 41/367 (11%)
Query: 3 FNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEP------------- 49
+ RP+ +Q++A+P++ + ++L+A +Q+G+GKTAAF+L +LSQ+
Sbjct: 198 YTRPTPVQKHAIPIIKGK--RDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKEN 255
Query: 50 -----ANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-- 102
+YP L L+PT ELA+Q + E+ KF ++ V + GQ+I +
Sbjct: 256 GRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE 312
Query: 103 ---QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRI---QRMLP 156
+++ TPG ++D + K I K VLDEAD M+ G + Q RI M P
Sbjct: 313 RGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRML-DMGFEPQIRRIVEQDTMPP 370
Query: 157 RNCQ-MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQAL 215
+ + ++FSATF + A+ + + + + R T + I Q V D++ L
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
Query: 216 CNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKE 275
L + + ++F T+K A L L EG+ + G+ R + +FR GK
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
Query: 276 KVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 335
+LV T V ARG+D+ V VINFDLP D E Y+HRIGRTGR G GLA + +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFN 544
Query: 336 SKHSMNI 342
K +MNI
Sbjct: 545 EK-NMNI 550
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 149 bits (377), Expect = 3e-36
Identities = 115/363 (31%), Positives = 181/363 (49%), Gaps = 40/363 (11%)
Query: 3 FNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEP------------- 49
+ RP+ +Q++A+P++ + ++L+A +Q+G+GKTAAF+L +LSQ+
Sbjct: 200 YTRPTPVQKHAIPII--KEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKEN 257
Query: 50 -----ANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-- 102
+YP L L+PT ELA+Q + E+ KF ++ V + GQ+I +
Sbjct: 258 GRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE 314
Query: 103 ---QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRI---QRMLP 156
+++ TPG ++D + K I K VLDEAD M+ G + Q RI M P
Sbjct: 315 RGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRML-DMGFEPQIRRIVEQDTMPP 372
Query: 157 RNCQ-MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQAL 215
+ + ++FSATF + A+ + + + + R T + I Q V D++ L
Sbjct: 373 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLL 432
Query: 216 CNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKE 275
L + ++F T+K A L L EG+ + G+ R + +FR GK
Sbjct: 433 DLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 492
Query: 276 KVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 335
+LV T V ARG+D+ V VINFDLP D E Y+HRIGRTGR G GLA + +
Sbjct: 493 PILVATAVAARGLDISNVKHVINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFN 546
Query: 336 SKH 338
++
Sbjct: 547 ERN 549
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 148 bits (374), Expect = 7e-36
Identities = 111/346 (32%), Positives = 180/346 (52%), Gaps = 20/346 (5%)
Query: 3 FNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML------SQVEPANKYPQC 56
+ +P+ IQ +P+ L+ +++I +++G+GKTAAF+ ML ++EP + P
Sbjct: 273 YTQPTPIQCQGVPVALSG--RDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDG-PIA 329
Query: 57 LCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE--QIVIGTPGTVLD 114
+ + PT EL Q ++ GK Y +A G+ E+ + + E +IV+ TPG ++D
Sbjct: 330 VIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLID 389
Query: 115 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 174
K K + +++ V DEAD M G + Q I + + Q LLFSATF + K
Sbjct: 390 HVKK-KATNLQRVSYLVFDEADRMF-DMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEK 447
Query: 175 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 234
A+ ++ DP + E + + Q + S K+ L T + +++ T+
Sbjct: 448 LARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTK 507
Query: 235 KT-ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQV 293
K A LA L +EGH + LL G+M +R VI F++ VLV T+V ARG+D+ +
Sbjct: 508 KANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSI 567
Query: 294 SVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHS 339
VIN+D+ D D T+ HRIGRTGR G++G+A ++ K S
Sbjct: 568 KTVINYDVARDID------THTHRIGRTGRAGEKGVAYTLLTPKDS 607
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 148 bits (374), Expect = 7e-36
Identities = 111/346 (32%), Positives = 180/346 (52%), Gaps = 20/346 (5%)
Query: 3 FNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML------SQVEPANKYPQC 56
+ +P+ IQ +P+ L+ +++I +++G+GKTAAF+ ML ++EP + P
Sbjct: 273 YTQPTPIQCQGVPVALSG--RDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDG-PIA 329
Query: 57 LCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE--QIVIGTPGTVLD 114
+ + PT EL Q ++ GK Y +A G+ E+ + + E +IV+ TPG ++D
Sbjct: 330 VIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLID 389
Query: 115 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 174
K K + +++ V DEAD M G + Q I + + Q LLFSATF + K
Sbjct: 390 HVKK-KATNLQRVSYLVFDEADRMF-DMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEK 447
Query: 175 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 234
A+ ++ DP + E + + Q + S K+ L T + +++ T+
Sbjct: 448 LARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTK 507
Query: 235 KT-ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQV 293
K A LA L +EGH + LL G+M +R VI F++ VLV T+V ARG+D+ +
Sbjct: 508 KANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSI 567
Query: 294 SVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHS 339
VIN+D+ D D T+ HRIGRTGR G++G+A ++ K S
Sbjct: 568 KTVINYDVARDID------THTHRIGRTGRAGEKGVAYTLLTPKDS 607
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 142 bits (359), Expect = 4e-34
Identities = 111/378 (29%), Positives = 190/378 (50%), Gaps = 26/378 (6%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
+G +P+ +Q +P +L ++ + +++G+GKTAAFVL +L ++ CL L+
Sbjct: 20 LGLKQPTPVQLGCIPAILEG--RDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLT 77
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRG-----NKLERGQKISEQIVIGTPGTVLDW 115
PT ELA Q + +GK LK V G LE +K +VI TPG + D
Sbjct: 78 PTRELAYQIAEQFRVLGKPLG-LKDCIIVGGMDMVAQALELSRK--PHVVIATPGRLADH 134
Query: 116 CSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML---PRNCQMLLFSATFEDSV 172
KKI+ V+DEAD ++ QG D ++ ++ +L P Q LLFSAT D++
Sbjct: 135 LRSSNTFSIKKIRFLVMDEADRLLE-QGCTDFTVDLEAILAAVPARRQTLLFSATLTDTL 193
Query: 173 WKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQA----M 228
+ P + + T++ + Q Y+L + K L +L +
Sbjct: 194 RELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEK-VKDAYLVHLIQRFQDEHEDWSII 252
Query: 229 IFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGI 288
IF +T KT L L K L M ++R A + +F+ ++L+ T+V +RG+
Sbjct: 253 IFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGL 312
Query: 289 DVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQE 348
D+ V VVIN + P G P + Y+HR+GRT R G++G A+ +V +++ +++++ I+E
Sbjct: 313 DIPTVQVVINHNTP----GLP--KIYIHRVGRTARAGRQGQAITLV-TQYDIHLVHAIEE 365
Query: 349 HFNKKIERLDTDDLDEIE 366
KK+E ++ + ++
Sbjct: 366 QIKKKLEEFSVEEAEVLQ 383
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 142 bits (357), Expect = 6e-34
Identities = 108/342 (31%), Positives = 173/342 (50%), Gaps = 18/342 (5%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQV--EPANK-YPQCL 57
MGF +P+ IQ+ +P+ L +++ A + +GTGKTAAF L +L ++ +P + L
Sbjct: 236 MGFKQPTPIQKACIPVGLLG--KDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVL 293
Query: 58 CLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG---NKLERGQKISEQIVIGTPGTVLD 114
L PT EL +Q V Q+ +F + AV G E + + I+I TPG ++D
Sbjct: 294 VLVPTRELGIQVHSVTRQLAQFC-NITTCLAVGGLDVKSQEAALRAAPDILIATPGRLID 352
Query: 115 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 174
I+V +LDEAD M+ + ++Q I RM + Q +LFSAT D V
Sbjct: 353 HLHNCPSFHLSSIEVLILDEADRML-DEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKD 411
Query: 175 FAQKVVPDPNVIKLKREEETLDTIKQYYV-LCSSRDEKFQALCNLYGAITIAQ-AMIFCH 232
A + +P I + + ++Q ++ + +R+ +A+ T M+F
Sbjct: 412 LASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQ 471
Query: 233 TRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQ 292
T+K A + L G QV L G + QR + RF++ + +LV T+V ARG+D+E
Sbjct: 472 TKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEG 531
Query: 293 VSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV 334
V VINF +P + Y+HR+GRT R G+ G +V++V
Sbjct: 532 VKTVINFTMP------NTIKHYVHRVGRTARAGRAGRSVSLV 567
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 133 bits (335), Expect = 2e-31
Identities = 111/376 (29%), Positives = 178/376 (47%), Gaps = 36/376 (9%)
Query: 3 FNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVE-----PANKYPQCL 57
F P+ IQ PL L+ ++++ +Q+G+GKT A++L + + P CL
Sbjct: 191 FTEPTPIQCQGFPLALSG--RDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICL 248
Query: 58 CLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-------NKLERGQKISEQIVIGTPG 110
L+PT ELA Q +V + GK LK G LERG +I I TPG
Sbjct: 249 VLAPTRELAQQVQQVADDYGKC-SRLKSTCIYGGAPKGPQIRDLERGV----EICIATPG 303
Query: 111 TVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFED 170
++D+ K + ++ VLDEAD M+ G + Q +I + + Q L++SAT+
Sbjct: 304 RLIDFLESGK-TNLRRCTYLVLDEADRML-DMGFEPQIRKIVDQIRPDRQTLMWSATWPK 361
Query: 171 SVWKFAQKVVPDPNVIKLKREEETLD-TIKQYYVLC--SSRDEKFQALCNLYGAITIAQA 227
V + A+ + D I + E + + I Q +C S +D K L A +
Sbjct: 362 EVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKT 421
Query: 228 MIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARG 287
+IF T++ L + ++G + G+ +R V+ FR GK +L+ T+V +RG
Sbjct: 422 IIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 288 IDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAV------NMVDSKHSMN 341
+DVE V VIN+D P +E Y+HRIGRT R +G A N+ ++ +
Sbjct: 482 LDVEDVKFVINYDYP------NSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535
Query: 342 ILNRIQEHFNKKIERL 357
+L + N K+ +L
Sbjct: 536 VLEEANQAINPKLMQL 551
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 133 bits (335), Expect = 2e-31
Identities = 111/376 (29%), Positives = 178/376 (47%), Gaps = 36/376 (9%)
Query: 3 FNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVE-----PANKYPQCL 57
F P+ IQ PL L+ ++++ +Q+G+GKT A++L + + P CL
Sbjct: 191 FTEPTPIQCQGFPLALSG--RDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICL 248
Query: 58 CLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-------NKLERGQKISEQIVIGTPG 110
L+PT ELA Q +V + GK LK G LERG +I I TPG
Sbjct: 249 VLAPTRELAQQVQQVADDYGKC-SRLKSTCIYGGAPKGPQIRDLERGV----EICIATPG 303
Query: 111 TVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFED 170
++D+ K + ++ VLDEAD M+ G + Q +I + + Q L++SAT+
Sbjct: 304 RLIDFLESGK-TNLRRCTYLVLDEADRML-DMGFEPQIRKIVDQIRPDRQTLMWSATWPK 361
Query: 171 SVWKFAQKVVPDPNVIKLKREEETLD-TIKQYYVLC--SSRDEKFQALCNLYGAITIAQA 227
V + A+ + D I + E + + I Q +C S +D K L A +
Sbjct: 362 EVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKT 421
Query: 228 MIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARG 287
+IF T++ L + ++G + G+ +R V+ FR GK +L+ T+V +RG
Sbjct: 422 IIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 288 IDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAV------NMVDSKHSMN 341
+DVE V VIN+D P +E Y+HRIGRT R +G A N+ ++ +
Sbjct: 482 LDVEDVKFVINYDYP------NSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535
Query: 342 ILNRIQEHFNKKIERL 357
+L + N K+ +L
Sbjct: 536 VLEEANQAINPKLMQL 551
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 133 bits (335), Expect = 2e-31
Identities = 97/368 (26%), Positives = 179/368 (48%), Gaps = 65/368 (17%)
Query: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
+G+ +P+KIQ A+PL L +++I +++G+GKT AF L +L+ + + L L+
Sbjct: 42 LGWTKPTKIQIEAIPLALQG--RDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLT 99
Query: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRG-NKLERGQKISEQ--IVIGTPGTVLDWCS 117
PT ELA Q + E +G ++ A V G + + + ++++ I+I TPG ++D
Sbjct: 100 PTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
Query: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177
K + + +K V+DEAD I + + +I +++PR+ + LFSAT V K +
Sbjct: 159 NTKGFNLRALKYLVMDEAD-RILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQR 217
Query: 178 KVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTA 237
+ +P + + +T++ ++QYY+ S KF++
Sbjct: 218 AALKNPVKCAVSSKYQTVEKLQQYYIFIPS---KFKS----------------------- 251
Query: 238 SWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVI 297
+R + +F+ +L+ T+V +RG+D+ V VV+
Sbjct: 252 ------------------------KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVV 287
Query: 298 NFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERL 357
NFD+P ++ Y+HR+GRT R G+ G A+ V +++ + + RI+ KK+
Sbjct: 288 NFDIPT------HSKDYIHRVGRTARAGRSGKAITFV-TQYDVELFQRIEHLIGKKLPGF 340
Query: 358 DTDDLDEI 365
T D DE+
Sbjct: 341 PTQD-DEV 347
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 133 bits (335), Expect = 2e-31
Identities = 98/342 (28%), Positives = 178/342 (52%), Gaps = 19/342 (5%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
G+ P+ IQ +P+ L ++++A + +G+GKTAAF+L ++ + +K P L L+P
Sbjct: 222 GYEVPTPIQMQMIPVGLLG--RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTP 279
Query: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRG----NKLERGQKISEQIVIGTPGTVLDWCS 117
T ELA+Q + +++ P +K V G +L R Q+ +++I TPG +LD
Sbjct: 280 TRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQ-HVKVIIATPGRLLD-II 337
Query: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177
K ++ +K+ V+DEAD M+ G Q Q + I +P +CQ +L SAT S+ + A
Sbjct: 338 KQSSVELCGVKIVVVDEADTML-KMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLAS 396
Query: 178 KVVPDPNVIKLKREEETLDTIKQ--YYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRK 235
+++ +P I + ++Q +V ++ +K + N + ++F +
Sbjct: 397 QLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILN-DKKLFKPPVLVFVDCKL 455
Query: 236 TASWLAAELSK-EGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS 294
A L+ + K G + + E +R +++ EG +V+V+T V RG+D+ V
Sbjct: 456 GADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVR 515
Query: 295 VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 336
+V+NFD+P D Y+H+IGR GR G+ G A+ +++
Sbjct: 516 LVVNFDMPSSMD------EYVHQIGRVGRLGQNGTAITFINN 551
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 133 bits (334), Expect = 3e-31
Identities = 106/372 (28%), Positives = 184/372 (49%), Gaps = 34/372 (9%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFV------LAMLSQVEPANKYPQ 55
GF +P+ IQ A P++L +LI +Q+GTGKT ++ L + ++ P
Sbjct: 261 GFQKPTPIQSQAWPIVLQGI--DLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPG 318
Query: 56 CLCLSPTYELALQTGKVIEQMGKF-YPELKLAYAVRGNKLERGQKISE-----QIVIGTP 109
L L+PT ELALQ V + K+ Y L+ G R ++I E I+I TP
Sbjct: 319 MLVLTPTRELALQ---VEGECCKYSYKGLRSVCVYGGGN--RDEQIEELKKGVDIIIATP 373
Query: 110 GTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFE 169
G + D F++ K I VLDEAD M+ G + Q ++I + + Q ++ SAT+
Sbjct: 374 GRLND-LQMSNFVNLKNITYLVLDEADKML-DMGFEPQIMKILLDVRPDRQTVMTSATWP 431
Query: 170 DSVWKFAQKVVPDPNVIKLKREE-ETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAM 228
SV + AQ + +P ++ + + + ++KQ ++ + ++ L + + +
Sbjct: 432 HSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVI 491
Query: 229 IFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGI 288
+F + A L+++L V L G+ R +E F+ GK ++L+ T++ +RG+
Sbjct: 492 VFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGL 551
Query: 289 DVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD------SKHSMNI 342
DV V+ V NFD P + E Y+HRIGRTGR G+ G+++ + + +NI
Sbjct: 552 DVHDVTHVYNFDFP------RNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINI 605
Query: 343 LNRIQEHFNKKI 354
L R + +++
Sbjct: 606 LERANQSIPEEL 617
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 132 bits (333), Expect = 4e-31
Identities = 110/351 (31%), Positives = 177/351 (50%), Gaps = 29/351 (8%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVE----PANKY---- 53
G+ + + +Q+ ++P++LA ++L+A +Q+G+GKTAAF+L +L+ + A+++
Sbjct: 307 GYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQ 364
Query: 54 -PQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIG 107
P+C+ ++PT EL Q + + KF + V + G I + I+
Sbjct: 365 EPECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCA 421
Query: 108 TPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQ-GHQDQSIRIQRMLP--RNCQMLLF 164
TPG ++D K K I K+IK VLDEAD M+ G + + + +P Q L+F
Sbjct: 422 TPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
Query: 165 SATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITI 224
SATF + + + A + + + + Q VL + K + L + I
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 540
Query: 225 AQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVC 284
+ M+F T+K A ++A L +E + G+ +R + FR GK VLV T+V
Sbjct: 541 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 600
Query: 285 ARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 335
ARG+D+E V VINFDLP D Y+HRIGRTGR G G A++ D
Sbjct: 601 ARGLDIENVQHVINFDLPSTID------EYVHRIGRTGRCGNTGRAISFFD 645
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 132 bits (333), Expect = 4e-31
Identities = 110/351 (31%), Positives = 177/351 (50%), Gaps = 29/351 (8%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVE----PANKY---- 53
G+ + + +Q+ ++P++LA ++L+A +Q+G+GKTAAF+L +L+ + A+++
Sbjct: 307 GYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQ 364
Query: 54 -PQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIG 107
P+C+ ++PT EL Q + + KF + V + G I + I+
Sbjct: 365 EPECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCA 421
Query: 108 TPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQ-GHQDQSIRIQRMLP--RNCQMLLF 164
TPG ++D K K I K+IK VLDEAD M+ G + + + +P Q L+F
Sbjct: 422 TPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
Query: 165 SATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITI 224
SATF + + + A + + + + Q VL + K + L + I
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 540
Query: 225 AQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVC 284
+ M+F T+K A ++A L +E + G+ +R + FR GK VLV T+V
Sbjct: 541 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 600
Query: 285 ARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 335
ARG+D+E V VINFDLP D Y+HRIGRTGR G G A++ D
Sbjct: 601 ARGLDIENVQHVINFDLPSTID------EYVHRIGRTGRCGNTGRAISFFD 645
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 132 bits (333), Expect = 4e-31
Identities = 110/351 (31%), Positives = 177/351 (50%), Gaps = 29/351 (8%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVE----PANKY---- 53
G+ + + +Q+ ++P++LA ++L+A +Q+G+GKTAAF+L +L+ + A+++
Sbjct: 273 GYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQ 330
Query: 54 -PQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISE-----QIVIG 107
P+C+ ++PT EL Q + + KF + V + G I + I+
Sbjct: 331 EPECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCA 387
Query: 108 TPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQ-GHQDQSIRIQRMLP--RNCQMLLF 164
TPG ++D K K I K+IK VLDEAD M+ G + + + +P Q L+F
Sbjct: 388 TPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 446
Query: 165 SATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITI 224
SATF + + + A + + + + Q VL + K + L + I
Sbjct: 447 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 506
Query: 225 AQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVC 284
+ M+F T+K A ++A L +E + G+ +R + FR GK VLV T+V
Sbjct: 507 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 566
Query: 285 ARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 335
ARG+D+E V VINFDLP D Y+HRIGRTGR G G A++ D
Sbjct: 567 ARGLDIENVQHVINFDLPSTID------EYVHRIGRTGRCGNTGRAISFFD 611
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 130 bits (328), Expect = 1e-30
Identities = 105/377 (27%), Positives = 179/377 (47%), Gaps = 52/377 (13%)
Query: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML---------SQVEPANK 52
G+ P+ IQ A+P+ L +++I +++G+GKTAAF++ +L ++E +++
Sbjct: 410 GYKEPTPIQRQAIPIGLQN--RDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQ 467
Query: 53 YPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQ----KISEQIVIGT 108
P + L+PT ELA Q + + GK P AV G Q ++ +IVI T
Sbjct: 468 GPYAIILAPTRELAQQIEEETIKFGK--PLGIRTVAVIGGISREDQGFRLRMGCEIVIAT 525
Query: 109 PGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP------------ 156
PG ++D +++ + VLDEAD MI G + +I +P
Sbjct: 526 PGRLIDVLEN-RYLVLSRCTYVVLDEADRMI-DMGFEPDVQKILEHMPVSNQKPDTDEAE 583
Query: 157 --------------RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYY 202
+ Q ++F+AT +V + A+ + P V+ + + + ++Q
Sbjct: 584 DPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKV 643
Query: 203 VLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQ 262
L S +++ + L L +IF + +K LA L K G+ L G EQ
Sbjct: 644 FLMSESEKRKKLLAILEQGFD-PPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQ 702
Query: 263 RAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTG 322
R + + G + +LV T+V RGID++ VS+V+N+D+ + E Y+HRIGRTG
Sbjct: 703 REFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMA------KNIEDYIHRIGRTG 756
Query: 323 RFGKRGLAVNMVDSKHS 339
R GK G+A+ + + S
Sbjct: 757 RAGKSGVAITFLTKEDS 773
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,269,559
Number of Sequences: 37866
Number of extensions: 543629
Number of successful extensions: 1630
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1380
Number of HSP's gapped (non-prelim): 112
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.