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Search of human proteins with 62177129
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62177129 Nedd4 binding protein 3 [Homo sapiens]
(544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62177129 Nedd4 binding protein 3 [Homo sapiens] 1085 0.0
gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo sa... 196 3e-50
gi|7662176 ProSAPiP1 protein [Homo sapiens] 191 2e-48
gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo sa... 152 1e-36
gi|221139761 zinc finger protein 853 [Homo sapiens] 62 1e-09
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 62 2e-09
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 59 1e-08
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 59 1e-08
gi|21735548 centrosomal protein 2 [Homo sapiens] 58 3e-08
gi|148746195 trichohyalin [Homo sapiens] 57 6e-08
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom... 56 7e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 1e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 1e-07
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 55 1e-07
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 55 1e-07
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 55 2e-07
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 55 2e-07
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 55 2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 2e-07
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 54 4e-07
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 53 6e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 8e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 52 1e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 52 1e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 52 1e-06
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] 52 2e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 51 2e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 51 2e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 51 3e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 51 3e-06
>gi|62177129 Nedd4 binding protein 3 [Homo sapiens]
Length = 544
Score = 1085 bits (2807), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MATAPGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFLSYLH 60
MATAPGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFLSYLH
Sbjct: 1 MATAPGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFLSYLH 60
Query: 61 LPKKDSKSTKNTKRAPRNEPADYATLYYREHSRAGDFSKTSLPERGRFDKCRIRPSVFKP 120
LPKKDSKSTKNTKRAPRNEPADYATLYYREHSRAGDFSKTSLPERGRFDKCRIRPSVFKP
Sbjct: 61 LPKKDSKSTKNTKRAPRNEPADYATLYYREHSRAGDFSKTSLPERGRFDKCRIRPSVFKP 120
Query: 121 TAGNGKGFLSMQSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEG 180
TAGNGKGFLSMQSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEG
Sbjct: 121 TAGNGKGFLSMQSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEG 180
Query: 181 GPEPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSC 240
GPEPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSC
Sbjct: 181 GPEPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSC 240
Query: 241 LPEPPPPYEFSCSSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRL 300
LPEPPPPYEFSCSSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRL
Sbjct: 241 LPEPPPPYEFSCSSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRL 300
Query: 301 YVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSA 360
YVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSA
Sbjct: 301 YVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSA 360
Query: 361 RPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELV 420
RPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELV
Sbjct: 361 RPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELV 420
Query: 421 RLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQ 480
RLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQ
Sbjct: 421 RLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQ 480
Query: 481 EQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLE 540
EQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLE
Sbjct: 481 EQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLE 540
Query: 541 SSKI 544
SSKI
Sbjct: 541 SSKI 544
>gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo
sapiens]
Length = 669
Score = 196 bits (499), Expect = 3e-50
Identities = 194/625 (31%), Positives = 263/625 (42%), Gaps = 104/625 (16%)
Query: 4 APGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGS---RQPDGLLRKGLGQREFLSYLH 60
A P MGSV SL+ + G G RQ DGLLR G +E L
Sbjct: 18 ATAPQAPVMGSVSSLISGRPCPGGPAPPRHHGPPGPTFFRQQDGLLRGGYEAQEPLCPAV 77
Query: 61 LPKKDSKSTK----NTKRAPRNEPADYATLYYREHSRAGDFSKTSLPER---------GR 107
P+K T N + P+ + + RA + P +
Sbjct: 78 PPRKAVPVTSFTYINEDFRTESPPSPSSDVEDAREQRAHNAHLRGPPPKLIPVSGKLEKN 137
Query: 108 FDKCRIRPSVFKPTAGNGKGFLSMQSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQA 167
+K IRP+ FKP +G S+ S + L S GSL L P S +S +
Sbjct: 138 MEKILIRPTAFKPVLPKPRGAPSLPSFMGPRATGLSGSQGSLTQLFGGPASSSSSSSSSS 197
Query: 168 RAQLLHALS------------------------LDEGGPEPEPSLSDS---SSGGSFGRS 200
A A S GG EP S S G G
Sbjct: 198 AADKPLAFSGWASGCPSGTLSDSGRNSLSSLPTYSTGGAEPTTSSPGGHLPSHGSGRGAL 257
Query: 201 PG------TGPSPF----SSSLGHLNHLGGSLDRASQGPKEAGPPAVLSC-----LPEPP 245
PG TGPS SSS LGG + G P SC P PP
Sbjct: 258 PGPARGVPTGPSHSDSGRSSSSKSTGSLGGRVAGGLLGSGTRASPDSSSCGERSPPPPPP 317
Query: 246 PPYEFSCSSAEEMGAVLPETCE--ELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVE 303
PP + + G + E +L+ L + + + Q EERQR W E + L E
Sbjct: 318 PPSDEALLHCVLEGKLRDREAELQQLRDSLDENEAT--MCQAYEERQRHWQREREALR-E 374
Query: 304 RLHEVTQKAERSERNLQLQLFMAQQEQRRLRKEL-RAQQGLAPEPRAPGTLPEADPSARP 362
Q+A+R+++ LQLQ+F QQE+R+L+ + + Q R TL P
Sbjct: 375 DCAAQAQRAQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGP 434
Query: 363 E-EEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRA----------- 410
EE +WEVCQK+ EISLLKQQL+E+QAEL QK +E+ +L+ LR +RA
Sbjct: 435 RLEETKWEVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARATLRVSEGRARG 494
Query: 411 ----------QAQAQDAELVRLREAVRSLQEQAPREEAPGS-----------------CE 443
+ +A EL R R+ L+E+A + +A + E
Sbjct: 495 LQEAARARELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATADPFLLAE 554
Query: 444 TDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRY 503
+D+ K + GGS R E+LR EL +ER RG+EQ FE ER WQ EKE+V+RY
Sbjct: 555 SDEAKVQRAAAGVGGS-LRAQVERLRVELQRERRRGEEQRDSFEGERLAWQAEKEQVIRY 613
Query: 504 QREIQGGYMDMYRRNQALEQELRAL 528
Q+++Q Y+ MYRRN+ LEQEL+ L
Sbjct: 614 QKQLQHNYIQMYRRNRQLEQELQQL 638
>gi|7662176 ProSAPiP1 protein [Homo sapiens]
Length = 673
Score = 191 bits (484), Expect = 2e-48
Identities = 199/663 (30%), Positives = 293/663 (44%), Gaps = 142/663 (21%)
Query: 5 PGPAGIAMGSVGS-LLERQDFSPEEL---------RAALAGSRGSRQPDGLLRKGLGQRE 54
P +AMGSVGS + Q+F+ + + + + G RGS R G E
Sbjct: 30 PPDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSE 89
Query: 55 FLS-----YLHLPKKDSKSTK-------NTKRAPRNEPADYATLYYREHSRAGDFSKTSL 102
YL+ + S T ++ + + +D A YRE S TS
Sbjct: 90 DKGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATS- 148
Query: 103 PERGRFDKCR---IRPSVFKPTAGNGKGFLSMQSLAS--------------------HKG 139
G+ D+C +RPS FKP K F SMQ+L K
Sbjct: 149 ---GKLDQCSEPLVRPSAFKPVVP--KNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKS 203
Query: 140 QKLWRSNGSLHTLAC--HPPLSPGPRASQARAQLLHALS-----LDEGGPEPEPSLSDSS 192
+ + + GS L+ L+ P S + +Q L LS ++ G S S S
Sbjct: 204 RTMTPAGGSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGS 263
Query: 193 SGGSFGRSP--------GTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSCLPEP 244
SGG G + S SSS+G HLG E G + P
Sbjct: 264 SGGGSGYQDLGTSDSGRASSKSGSSSSMGRPGHLGSG---------EGGGGGLPFAACSP 314
Query: 245 PPPYEFSCSSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLW---LAELKRLY 301
P P E + E L+R L E QVLEERQ+ W LAEL++
Sbjct: 315 PSPSALIQELEERLWEKEQEVAA-LRRSL--EQSEAAVAQVLEERQKAWERELAELRQGC 371
Query: 302 VERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKE---LRAQQGLAPEPRAPGTLPEADP 358
+L +V ++A+R+++ LQLQ+ QQ++++L++E L Q+ + A +AD
Sbjct: 372 SGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADF 431
Query: 359 SARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAE 418
R EE +WEVCQK EISLLKQQL+++QA+++QKL+EI L++QLR RA + ++ +
Sbjct: 432 LPRIEE-TKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQ 490
Query: 419 LVRLREAVRSLQ----------------------EQAPREEAPGSCETDDCKSRGLLG-- 454
L+ LR++ S Q + A ++A +CE+D+ K R G
Sbjct: 491 LLSLRDSFSSKQASLELGEGELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVA 550
Query: 455 ------------EAGGSEA----RDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKE 498
EAGG R +L+AEL ER + Q F +ERR W EEKE
Sbjct: 551 AAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKE 610
Query: 499 RVLRYQREIQGGYMDMYRRNQALEQELRAL-----REPPTP--------WSP----RLES 541
+V+ YQ+++Q Y++MY+RNQ LE+ LR PTP W+P R+ES
Sbjct: 611 KVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIES 670
Query: 542 SKI 544
++I
Sbjct: 671 TEI 673
>gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo
sapiens]
Length = 596
Score = 152 bits (383), Expect = 1e-36
Identities = 168/607 (27%), Positives = 258/607 (42%), Gaps = 112/607 (18%)
Query: 12 MGSVGSLLERQDFSPEELRAALAGSRGS-------RQPDGLLRKGLGQREFLSYLHLPKK 64
MGSV SL+ F + RA+ R S R DGLLR G Q + K
Sbjct: 1 MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDS--GHGKSSSK 58
Query: 65 DSKST-----KNTKRAPRNEPADYATLYYRE-HSRAG-DFSKTSLPERGRF--------D 109
KS K +++A + DY L + +AG DF ++ P+ F +
Sbjct: 59 MGKSEDFFYIKVSQKARGSHHPDYTALSSGDLGGQAGVDFDPSTPPKLMPFSNQLEMGSE 118
Query: 110 KCRIRPSVFKPTAGNGKGFL-SMQSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQAR 168
K +RP+ FKP L S ASH+ HP P+ + +
Sbjct: 119 KGAVRPTAFKPVLPRSGAILHSSPESASHQ---------------LHPAPPDKPKEQELK 163
Query: 169 AQLLHALSLDEGGPEPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHLNHLGGSLDRASQG 228
L +L + G SL S+ S+ P P +G + GGS +QG
Sbjct: 164 PGLCSG-ALSDSGRNSMSSLPTHSTSSSYQLDPLVTP------VGPTSRFGGSAHNITQG 216
Query: 229 ---------------------------PKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAV 261
+ GP SC+ P E S E+
Sbjct: 217 IVLQDSNMMSLKALSFSDGGSKLGHSNKADKGP----SCVRSPISTDECSIQELEQKLLE 272
Query: 262 LPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVE---RLHEVTQKAERSERN 318
++L+R +++ ++ EER R EL+ + +L + +QK++R+++
Sbjct: 273 REGALQKLQRSFEEKELASSLAY--EERPRRCRDELEGPEPKGGNKLKQASQKSQRAQQV 330
Query: 319 LQLQLFMAQQEQRRLRKELRA---QQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTA 375
L LQ+ QQE+R+LR+EL + +Q L E + E EE +WEVCQK+
Sbjct: 331 LHLQVLQLQQEKRQLRQELESLMKEQDLL-ETKLRSYEREKTSFGPALEETQWEVCQKSG 389
Query: 376 EISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSL------ 429
EISLLKQQL+E+Q E+ K +EI LK QL+ +R + + + L A+R+
Sbjct: 390 EISLLKQQLKESQTEVNAKASEILGLKAQLKDTRGKLEGLELRTQDLEGALRTKGLELEV 449
Query: 430 ---QEQAPREEAPGSCETDDCKSRGLLG-EAGGSEARDSA---------------EQLRA 470
+ Q + EA E + + L A + ARD E+LRA
Sbjct: 450 CENELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGPPTFPEDVPALQRELERLRA 509
Query: 471 ELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
EL +ER + + F+ ER W+EEKE+V++YQ+++Q Y+ MY+RNQ LE+ L+ L
Sbjct: 510 ELREERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYVAMYQRNQRLEKALQQLAR 569
Query: 531 PPTPWSP 537
+ P
Sbjct: 570 GDSAGEP 576
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 62.4 bits (150), Expect = 1e-09
Identities = 95/411 (23%), Positives = 174/411 (42%), Gaps = 72/411 (17%)
Query: 155 HPPLSPGPRASQARAQL--------LHALSLDEGGPEPEPSLSDSSSGGSFGRSPGTGPS 206
H P +PG R AR ++ L L++GGP P D+ SGGS G
Sbjct: 3 HQP-TPGNRGLTARMEVGPATETFVLELQCLEDGGPGP-----DTLSGGSGGSESQEEEE 56
Query: 207 PFSSSLGHLNHLGGSLDRASQGPKEAGP---PAVLSCLPEPPPPYEFSCSSAEEMGAVLP 263
P + + AS+ +E P L L + P P + + P
Sbjct: 57 PQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQ----QPQHEQLQQP 112
Query: 264 ETCEELKRGLGDEDGSNPFTQVLEER-QRLWLAELK----------RLYVERLHEVTQKA 312
+ EL++ +DG +Q+ +E+ Q + ELK +L +++ E Q+
Sbjct: 113 QPHLELQQQ-PQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQE-QQRL 170
Query: 313 ERSERNLQLQLFMAQQ---EQRRLRKELRAQQGLAPEP---RAPGTLPEADPSARPEEEA 366
++ + LQ Q QQ +Q +L+++++ QQ L + + L + + + + +
Sbjct: 171 QQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQ 230
Query: 367 RWEVCQKTAEISLLKQQ-------LREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAEL 419
+ E Q+ ++ LL+QQ L++ QA+L Q+L E + QAQ Q L
Sbjct: 231 QQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLE-----------QQQAQLQQQLL 279
Query: 420 VRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELL------ 473
++ +E ++ Q+Q ++ + + L E E++ EL+
Sbjct: 280 LQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPE--------EEEEVELELMPVDLGS 331
Query: 474 QERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQE 524
++ L Q Q L +QE QE+++ L+ Q E+Q + ++ Q LEQ+
Sbjct: 332 EQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQ 382
Score = 38.1 bits (87), Expect = 0.021
Identities = 46/240 (19%), Positives = 107/240 (44%), Gaps = 19/240 (7%)
Query: 307 EVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQG-----LAPEPRAPGTLPEADPSAR 361
E+ ++ +R LQLQ Q E ++ + + QQ L +P+ G +
Sbjct: 77 EIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQE 136
Query: 362 PEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVR 421
+ + + ++ +QQL+ Q + Q+L + + QL+ +AQ Q + +
Sbjct: 137 KHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQ---QQEQLQTQQAQEQQVLQQQEQ 193
Query: 422 LREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELL-------Q 474
L++ V+ ++Q +++ + + + L + + ++ +Q + LL Q
Sbjct: 194 LQQQVQ--EQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQ 251
Query: 475 ERLRGQEQALRFEQ--ERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPP 532
++L Q+QA +Q E++ Q +++ +L+ Q ++Q + Q + + + L+ PP
Sbjct: 252 QQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPP 311
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 61.6 bits (148), Expect = 2e-09
Identities = 101/392 (25%), Positives = 159/392 (40%), Gaps = 55/392 (14%)
Query: 158 LSPGPRASQARAQLLHALSLDEGGPEPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHLNH 217
LS R + A L LS + PS SS G GRSP GPSP S L
Sbjct: 470 LSGSERTADASNGSLRGLS-----GQRTPSPPRRSSPGR-GRSPRRGPSPACSDSSTLAL 523
Query: 218 LGGSLDRAS------QGPKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAVLPETCEELKR 271
+ +L + +G EA +L L + S +E L E + L+
Sbjct: 524 IHSALHKRQLQVQDMRGRYEASQD-LLGTLRK-------QLSDSESERRALEEQLQRLR- 574
Query: 272 GLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQR 331
D ++ Q E+ QR V+RL + R + NL L +AQQ+
Sbjct: 575 -----DKTDGAMQAHEDAQR---------EVQRLRSANELLSREKSNLAHSLQVAQQQAE 620
Query: 332 RLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAE- 390
LR+E Q E R + D +E+A + + E+ +QL + + +
Sbjct: 621 ELRQEREKLQAAQEELRR-----QRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKR 675
Query: 391 --LAQKLAEIFSLKTQLRGSRAQAQAQDAELVRL---REAVR-SLQEQAPREEAPGSCET 444
LA++L E+ ++ R QA+ AE+ EA R L+ + A +
Sbjct: 676 SVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQ 735
Query: 445 DDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERV--LR 502
D L E+ + D +L A+L +E+ Q + + EQE +EE+ER+ LR
Sbjct: 736 DSLSKLSALNESLAQDKLD-LNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 794
Query: 503 YQREI-----QGGYMDMYRRNQALEQELRALR 529
++E+ +G + +ALEQ+L LR
Sbjct: 795 LEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 826
Score = 47.4 bits (111), Expect = 3e-05
Identities = 91/392 (23%), Positives = 144/392 (36%), Gaps = 72/392 (18%)
Query: 194 GGSFGRSPGTGPSPFSSSLGHLNHLGGSLDRASQGPKEA-GPPAVLSCLPEPPPPYEFSC 252
G GR+P P P S D ++G E P+ L C P PP
Sbjct: 1443 GLGLGRAPSPAPRPVPGSPAR--------DAPAEGSGEGLNSPSTLECSPGSQPPSPGPA 1494
Query: 253 SSA-------EEMGAVLPETCEELKRGLGDEDGSNPFTQVL------------------- 286
+S E + L E +EL+ + D T L
Sbjct: 1495 TSPASPDLDPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRAR 1554
Query: 287 ---------EERQRLWLAELKRLYVERL--HEVTQKAERSERNLQLQLFMAQQEQRRLRK 335
EE +R L + E E +++ER R Q+ ++ +
Sbjct: 1555 QLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATES 1614
Query: 336 ELRAQQGLAPEPRAPGTLPEADP-------SARPEEEARWEVCQKTAEISLLKQQL---- 384
ELRA Q + +A T E D A + E+ +++ E L + +L
Sbjct: 1615 ELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSD 1674
Query: 385 REAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQ--APREEAPGSC 442
REAQA+ Q + SL+ Q+ S +A + RL A+ ++E A R++ G
Sbjct: 1675 REAQAQALQD--RVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLT 1732
Query: 443 ETDDCKSRGLLGEAGGS----EARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKE 498
E S L + +A + E R ++LQERL QAL +++ + E+
Sbjct: 1733 EALAQSSASLNSTRDKNLHLQKALTACEHDR-QVLQERLDAARQALSEARKQSSSLGEQV 1791
Query: 499 RVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
+ LR G D+ + E +L+ LRE
Sbjct: 1792 QTLR------GEVADLELQRVEAEGQLQQLRE 1817
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/269 (24%), Positives = 115/269 (42%), Gaps = 45/269 (16%)
Query: 296 ELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPE 355
+L RL V +L E + +R + + +A++EQ RL +ELR +Q +A +
Sbjct: 754 DLNRL-VAQLEEEKSALQGRQRQAEQEATVAREEQERL-EELRLEQEVARQG-------- 803
Query: 356 ADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQ 415
+ S R E+A+ + Q+ + + QL+E A+L+++L+ + +L +R +AQ Q
Sbjct: 804 LEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLS---GREQELEQARREAQRQ 860
Query: 416 ---------------------DAELVRLREAVRSLQEQAPR-----EEAPGSCETDDCKS 449
+LV R+L E+A R E GS +
Sbjct: 861 VEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQL 920
Query: 450 RGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEE--KERVLRYQREI 507
L EA A L E L L G Q + QE+ + +E +++++ +RE
Sbjct: 921 AQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREA 980
Query: 508 QGGYMDMYRRNQALEQELRAL-REPPTPW 535
Q + + A E++L+ L RE W
Sbjct: 981 QA---SLREQRAAHEEDLQRLQREKEAAW 1006
Score = 42.7 bits (99), Expect = 8e-04
Identities = 48/225 (21%), Positives = 95/225 (42%), Gaps = 22/225 (9%)
Query: 303 ERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGT-LPEADPSAR 361
E+L +++++ E+ L+ AQ++ L + R ++ LA E L A+ R
Sbjct: 834 EQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGR 893
Query: 362 PEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVR 421
E E + E L+ L E Q +LAQ A L+ + + + EL
Sbjct: 894 TLSE---EATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAG 950
Query: 422 LREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQE 481
LR+ + + QE+A ++ E + + + +A L ++R +E
Sbjct: 951 LRQQIIATQEKASLDK-----------------ELMAQKLVQAEREAQASLREQRAAHEE 993
Query: 482 QALRFEQERR-TWQEEKERVLRYQREIQGGYMDMYRRNQALEQEL 525
R ++E+ W+E + + Q ++Q ++ R +A ++EL
Sbjct: 994 DLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEEL 1038
Score = 39.7 bits (91), Expect = 0.007
Identities = 43/142 (30%), Positives = 67/142 (47%), Gaps = 26/142 (18%)
Query: 384 LREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCE 443
L+E L Q+L+ + L AQ++A+ EL AV EQA R E PG E
Sbjct: 79 LQEENQLLQQELSRVEDLL-------AQSRAERDELAIKYNAVSERLEQALRLE-PGELE 130
Query: 444 TDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRY 503
T + RGL+ R S E LR +L QE+ + ++ + +QE ++R +
Sbjct: 131 TQE--PRGLV--------RQSVE-LRRQL-------QEEQASYRRKLQAYQEGQQRQAQL 172
Query: 504 QREIQGGYMDMYRRNQALEQEL 525
+ +QG + +R LEQ+L
Sbjct: 173 VQRLQGKILQYKKRCSELEQQL 194
Score = 39.3 bits (90), Expect = 0.009
Identities = 60/278 (21%), Positives = 108/278 (38%), Gaps = 31/278 (11%)
Query: 256 EEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERS 315
EE+ + +E GL + L+E ++ L+E L ++ + ER
Sbjct: 1036 EELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQ 1095
Query: 316 ERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTA 375
+R+ Q + + L ELR D A+ EE A
Sbjct: 1096 KRDAQSRQEQDRSTVNALTSELR------------------DLRAQREEAA----AAHAQ 1133
Query: 376 EISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQE--QA 433
E+ L++Q R+ + L E L+TQLR EL+ + +R QE +
Sbjct: 1134 EVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREV 1193
Query: 434 PREEAPGSCET--DDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERR 491
R+EA + + K R L E R + ++ +E + +L +++ EQ+
Sbjct: 1194 QRQEAGELRRSLGEGAKEREAL-RRSNEELRSAVKKAESERISLKLANEDK----EQKLA 1248
Query: 492 TWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALR 529
+E + V + E++ G ++ R +EL+ LR
Sbjct: 1249 LLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELR 1286
Score = 39.3 bits (90), Expect = 0.009
Identities = 70/289 (24%), Positives = 109/289 (37%), Gaps = 36/289 (12%)
Query: 287 EERQRLWLAELKRLYVER--LHEVTQKAERSERNLQLQLFMAQQEQRRLRKEL------- 337
EE E++RL + L + R L+ QL + + + LR+EL
Sbjct: 1125 EEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL 1184
Query: 338 -RAQQGLAPEPRAPGTL--------PEADPSARPEEEARWEVCQKTAEISLLKQQLREAQ 388
+Q+G + + G L E + R EE R V + +E + L+ A
Sbjct: 1185 RESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESE----RISLKLAN 1240
Query: 389 AELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLR-EAVRSLQE------QAPREEAPGS 441
+ QKLA + +T + + + E+ R R EA R LQE E
Sbjct: 1241 EDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLG 1300
Query: 442 CETDDCKSRGLLGEAGGSEARDSAEQLRAELL--QERLRGQEQALRFEQERRTWQE---- 495
E + + R LGE E+R LR LL + L Q L+ Q + QE
Sbjct: 1301 RELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFR 1360
Query: 496 -EKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLESSK 543
+ R+L E +G + LE +L A R RL +++
Sbjct: 1361 TRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAE 1409
Score = 38.9 bits (89), Expect = 0.012
Identities = 64/244 (26%), Positives = 97/244 (39%), Gaps = 34/244 (13%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPE 346
E + L E + + E L + ++ E + R L+ + Q + +R ++EL A+
Sbjct: 977 EREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARL----- 1031
Query: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLR 406
EA+ EE A + Q+ E LL + E Q L+ K +E +L +L
Sbjct: 1032 --------EAEKEELSEEIAALQ--QERDEGLLLAES--EKQQALSLKESEKTALSEKLM 1079
Query: 407 GSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAE 466
G+R E+ R + +S QEQ D L E + R E
Sbjct: 1080 GTRHSLATISLEMERQKRDAQSRQEQ------------DRSTVNALTSEL--RDLRAQRE 1125
Query: 467 QLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELR 526
+ A QE R QEQA ++R + E E LR Q + D RR L + R
Sbjct: 1126 EAAAAHAQEVRRLQEQARDLGKQRDSCLREAEE-LRTQLRLLEDARDGLRRE--LLEAQR 1182
Query: 527 ALRE 530
LRE
Sbjct: 1183 KLRE 1186
Score = 37.4 bits (85), Expect = 0.035
Identities = 67/265 (25%), Positives = 105/265 (39%), Gaps = 52/265 (19%)
Query: 286 LEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
LEE+ R + K L +++ KA+ S R +L L + + E++ L K+ + + L
Sbjct: 367 LEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKD-QVNKDLTE 425
Query: 346 EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQL 405
+ EA S R +E+A E T + L+Q LR +LAQ + QL
Sbjct: 426 K-------LEALESLRLQEQAALE----TEDGEGLQQTLR----DLAQAVLSDSESGVQL 470
Query: 406 RGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSA 465
GS A A + LR PR +PG RG G S A +
Sbjct: 471 SGSERTADASNGS---LRGLSGQRTPSPPRRSSPG---------RGRSPRRGPSPACSDS 518
Query: 466 EQL--------RAELLQERLRGQEQALR------------FEQERRTWQEEKERVLRYQR 505
L + +L + +RG+ +A + E ERR +E+ +R+ R
Sbjct: 519 STLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRL----R 574
Query: 506 EIQGGYMDMYRRNQALEQELRALRE 530
+ G M + Q Q LR+ E
Sbjct: 575 DKTDGAMQAHEDAQREVQRLRSANE 599
Score = 29.3 bits (64), Expect = 9.6
Identities = 55/218 (25%), Positives = 85/218 (38%), Gaps = 29/218 (13%)
Query: 346 EPRAPGTLPEAD-PSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFS-LKT 403
+P +P LP + S +E + Q+ + + L Q R + ELA K + L+
Sbjct: 61 QPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQ 120
Query: 404 QLRGSRAQAQAQDAE-LVRLR-EAVRSLQE-QAPREEAPGSCETDDCKSRGLLGEAGG-- 458
LR + + Q+ LVR E R LQE QA + + + L+ G
Sbjct: 121 ALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKI 180
Query: 459 -------SEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKER---------VLR 502
SE + EL Q+RLR E + E +EE++R +LR
Sbjct: 181 LQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLR 240
Query: 503 YQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLE 540
Q + G NQAL +++R + T LE
Sbjct: 241 EQLDQAGS------ANQALSEDIRKVTNDWTRCRKELE 272
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 58.5 bits (140), Expect = 1e-08
Identities = 71/248 (28%), Positives = 110/248 (44%), Gaps = 29/248 (11%)
Query: 267 EELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAER-----SERNLQL 321
E L+R E+ Q +EE +R L E+K ERL +V Q ER E+ Q+
Sbjct: 543 ENLRR---KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 599
Query: 322 QLFMAQ-QEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLL 380
+ AQ E+ KE R + A + A + E + + EEEAR + L
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR--------RLRWL 651
Query: 381 KQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPG 440
+Q+ E + + E+ K + R + A+ L RE R +EQ RE+
Sbjct: 652 QQEEEERRHQ------ELLQKKKEEEQERLRKAAEAKRLAEQREQER--REQERREQERR 703
Query: 441 SCETDDCKSRGLLGEAGGSEARDSAEQLRAEL-LQER---LRGQEQALRFEQERRTWQEE 496
E + + R + E R E+L+AE LQER LR Q++ L+ E E + +EE
Sbjct: 704 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 763
Query: 497 KERVLRYQ 504
++R+ Q
Sbjct: 764 QQRLAERQ 771
Score = 47.4 bits (111), Expect = 3e-05
Identities = 57/243 (23%), Positives = 112/243 (46%), Gaps = 17/243 (6%)
Query: 301 YVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSA 360
+VE+ + + R E QL+ ++++RR +E++ ++ E R L +
Sbjct: 534 FVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKR----EERLRKVLQARERVE 589
Query: 361 RPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELV 420
+ +EE + ++ QK A+I ++ +E + LA++ A+ + ++ A+ + Q+ E
Sbjct: 590 QMKEEKKKQIEQKFAQIDEKTEKAKEER--LAEEKAKKKAAAKKMEEVEARRK-QEEEAR 646
Query: 421 RLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQ 480
RLR + +E+ +E E + + R +EA+ AEQ E ++ R Q
Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEEQERLRK------AAEAKRLAEQREQERREQERREQ 700
Query: 481 EQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLE 540
E R EQERR QE +E+ + + + + + + L++ +ALR LE
Sbjct: 701 E---RREQERRE-QERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 756
Query: 541 SSK 543
K
Sbjct: 757 EKK 759
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 58.5 bits (140), Expect = 1e-08
Identities = 71/248 (28%), Positives = 110/248 (44%), Gaps = 29/248 (11%)
Query: 267 EELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAER-----SERNLQL 321
E L+R E+ Q +EE +R L E+K ERL +V Q ER E+ Q+
Sbjct: 539 ENLRR---KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
Query: 322 QLFMAQ-QEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLL 380
+ AQ E+ KE R + A + A + E + + EEEAR + L
Sbjct: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR--------RLRWL 647
Query: 381 KQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPG 440
+Q+ E + + E+ K + R + A+ L RE R +EQ RE+
Sbjct: 648 QQEEEERRHQ------ELLQKKKEEEQERLRKAAEAKRLAEQREQER--REQERREQERR 699
Query: 441 SCETDDCKSRGLLGEAGGSEARDSAEQLRAEL-LQER---LRGQEQALRFEQERRTWQEE 496
E + + R + E R E+L+AE LQER LR Q++ L+ E E + +EE
Sbjct: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
Query: 497 KERVLRYQ 504
++R+ Q
Sbjct: 760 QQRLAERQ 767
Score = 44.7 bits (104), Expect = 2e-04
Identities = 56/241 (23%), Positives = 110/241 (45%), Gaps = 17/241 (7%)
Query: 303 ERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARP 362
E+ + + R E QL+ ++++RR +E++ ++ E R L + +
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKR----EERLRKVLQARERVEQM 587
Query: 363 EEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRL 422
+EE + ++ QK A+I ++ +E + LA++ A+ + ++ A+ + Q+ E RL
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEER--LAEEKAKKKAAAKKMEEVEARRK-QEEEARRL 644
Query: 423 REAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQ 482
R + +E+ +E E + + R +EA+ AEQ E ++ R QE
Sbjct: 645 RWLQQEEEERRHQELLQKKKEEEQERLRK------AAEAKRLAEQREQERREQERREQE- 697
Query: 483 ALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLESS 542
R EQERR QE +E+ + + + + + + L++ +ALR LE
Sbjct: 698 --RREQERRE-QERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 543 K 543
K
Sbjct: 755 K 755
Score = 37.7 bits (86), Expect = 0.027
Identities = 52/218 (23%), Positives = 97/218 (44%), Gaps = 24/218 (11%)
Query: 316 ERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEA--RWEVCQK 373
+RN L++ ++E++RL R ++ A + R E D R EE R E +K
Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEE--AEQLRRQKV--EEDKRRRLEEVKLKREERLRK 576
Query: 374 TAEISLLKQQLREAQA-ELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQ 432
+ +Q++E + ++ QK A+I KT+ +A+ + E + + A + ++E
Sbjct: 577 VLQARERVEQMKEEKKKQIEQKFAQIDE-KTE----KAKEERLAEEKAKKKAAAKKMEEV 631
Query: 433 APREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRT 492
R + + ++ + L + Q + E QERLR +A R ++R
Sbjct: 632 EARRK-----QEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
Query: 493 WQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
+ E+ER + +RE + RR Q ++ R L E
Sbjct: 687 ERREQERREQERREQE-------RREQERREQERQLAE 717
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 57.8 bits (138), Expect = 3e-08
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 18/239 (7%)
Query: 303 ERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRA-----QQGLAPEPRAPGTLPEAD 357
++L E ++ E E++LQ QL AQ+ + +EL A QQ E R +AD
Sbjct: 1785 QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVK---EKAD 1841
Query: 358 PSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDA 417
E+A + ++ E+ K+Q R + ELA + + +L+ L RA+++ Q+
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 418 ELVRLREAVRSLQEQAPRE---------EAPGSCETDDCKSRGLLGEAGGSEARDSAEQL 468
L+ L++ ++ E +A + D + L E+ S ++ A +
Sbjct: 1902 ALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARA 1961
Query: 469 RAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYR-RNQALEQELR 526
RAE LQE L AL+ +++ Q E R L +D + ++ LE+ LR
Sbjct: 1962 RAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Score = 57.0 bits (136), Expect = 4e-08
Identities = 70/287 (24%), Positives = 127/287 (44%), Gaps = 29/287 (10%)
Query: 256 EEMGAVLPETCEELKRGLGDEDGSNPFTQVLEER-QRLWLAELKRLYVERLHEVTQKAER 314
+++ L + EEL+ ++ + L +R Q + E + L ER E + +
Sbjct: 2038 QQLQQALAQRDEELRH---QQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQ 2094
Query: 315 SERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEE-EARWEVCQK 373
S R LQL L +QE LR E + + L P + T P + S + + E R + +
Sbjct: 2095 SVRELQLTLAQKEQEILELR-ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELE 2153
Query: 374 TAEISLLKQQLREAQ---------AELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLRE 424
+ +L + + RE + LAQ A + SL+ +A +D+E RL++
Sbjct: 2154 RLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQD 2213
Query: 425 AVRSLQEQAPREE--APGSCETDDCKSRG----LLGEAGGSEARDSAEQLRAELLQERLR 478
+ + +E +PG+ T + SRG LGE G EA S + + + ++RL
Sbjct: 2214 ELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLE 2273
Query: 479 GQEQAL-RFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQE 524
+QA+ R E +R R+ R+ +++ + R + L++E
Sbjct: 2274 HLQQAVARLEIDR-------SRLQRHNVQLRSTLEQVERERRKLKRE 2313
Score = 42.0 bits (97), Expect = 0.001
Identities = 52/192 (27%), Positives = 80/192 (41%), Gaps = 25/192 (13%)
Query: 359 SARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQ--- 415
S EE+++WE Q + E L+ +L E A L +L + + +G R QA
Sbjct: 1295 SQNQEEKSKWEGKQNSLESELM--ELHETMASLQSRLRRAELQRMEAQGERELLQAAKEN 1352
Query: 416 -DAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLL----GEAGGSEARDSAEQLRA 470
A++ L+ AV + QA A G E D +R L E R A Q +
Sbjct: 1353 LTAQVEHLQAAVVEARAQA---SAAGILEEDLRTARSALKLKNEEVESERERAQALQEQG 1409
Query: 471 EL-------LQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGG-----YMDMYRRN 518
EL LQE L Q L +E + + L QRE+Q +D+ +RN
Sbjct: 1410 ELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRN 1469
Query: 519 QALEQELRALRE 530
Q ++ + ++E
Sbjct: 1470 QEVDLQQEQIQE 1481
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/230 (22%), Positives = 96/230 (41%), Gaps = 19/230 (8%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEA--- 366
QKAE + LQ L Q+E+ ++K+L + + A L + A+ +EE
Sbjct: 669 QKAEEAGAELQADLRDIQEEKEEIQKKL--SESRHQQEAATTQLEQLHQEAKRQEEVLAR 726
Query: 367 ----RWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRL 422
+ + ++ A + + Q + + +LA++L + S K L S +AQ Q++ ++ +
Sbjct: 727 AVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS-VIEV 785
Query: 423 REAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSE-ARDSAEQLRAELLQERLRGQE 481
+ +Q Q + C L E +E RD+A + A+ QE E
Sbjct: 786 TKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALE 845
Query: 482 Q-----ALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELR 526
Q Q R W++E+ +Q+E+ + R LE L+
Sbjct: 846 QQKAAHEKEVNQLREKWEKERS---WHQQELAKALESLEREKMELEMRLK 892
Score = 40.4 bits (93), Expect = 0.004
Identities = 37/134 (27%), Positives = 67/134 (50%), Gaps = 20/134 (14%)
Query: 328 QEQRRLRKELRAQQG-----LAPEPRAPGTLPEADPSARPE--------EEARWEVCQKT 374
QE R++KEL ++ L + + L EAD + E +EA+ E + +
Sbjct: 1041 QEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELS 1100
Query: 375 AEISLLKQQLREAQAEL----AQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
A++ LL+Q+++E +A+ AQ L E+ + + RA AQ+A+ +L+ +RS +
Sbjct: 1101 AQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTE 1160
Query: 431 EQAPR---EEAPGS 441
Q E+ PG+
Sbjct: 1161 SQLEALAAEQQPGN 1174
Score = 38.5 bits (88), Expect = 0.016
Identities = 63/286 (22%), Positives = 123/286 (43%), Gaps = 57/286 (19%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMA----QQEQRRLRKELRAQQG 342
E+ + L + K + + ++++ +K E+ Q +L A ++E+ L L+ QQ
Sbjct: 837 EQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQ- 895
Query: 343 LAPEPRAPGTLPEADPSARPEEEARWE--VCQKTAE-----ISLLKQQLREAQAELAQKL 395
T EA + R EE + E +CQ E +SLL + L + Q ELA
Sbjct: 896 ---------TEMEAIQAQREEERTQAESALCQMQLETEKERVSLL-ETLLQTQKELADAS 945
Query: 396 AEIFSLKTQLRGSRAQAQAQDAEL-VRLREAVRSLQEQAPR--------EEAPGSCETDD 446
++ L+ ++ + + Q L +L+EA R L+E A + +E S D
Sbjct: 946 QQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDK 1005
Query: 447 CKSRGLLGEAGGS-EARDSAEQLRAELLQERLRGQEQALRFEQERR--------TWQEEK 497
+ + + A+D +++L + +QE+LR ++ R ++E + E++
Sbjct: 1006 MDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKE 1065
Query: 498 ERVLRYQ-----------------REIQGGYMDMYRRNQALEQELR 526
+R+L Q +E QG ++ + + L QE++
Sbjct: 1066 QRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 1111
Score = 37.4 bits (85), Expect = 0.035
Identities = 66/290 (22%), Positives = 104/290 (35%), Gaps = 61/290 (21%)
Query: 307 EVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEP---------RAPGTLPEAD 357
E+++ E S LQ L Q R+L + LR Q+G + + L + D
Sbjct: 1989 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRD 2048
Query: 358 PSARPEEEARWEVCQKTA----------------------EISLLKQQLREAQAELAQKL 395
R ++E R ++ +K+ EI L Q +RE Q LAQK
Sbjct: 2049 EELRHQQE-REQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKE 2107
Query: 396 AEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGE 455
EI L+ + + +A + + E L PR + E + ++ E
Sbjct: 2108 QEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQR----ELERLQAALRQTE 2163
Query: 456 AGGSEARDSAEQLRAELLQER----------LRGQEQALRFEQERRTWQEEKE---RVLR 502
A E R+ A+ L L Q + + Q L + E++ Q+E E R L
Sbjct: 2164 AREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALE 2223
Query: 503 YQREIQGGYMDMYRRNQALEQ-----ELRALREPPTP-------WSPRLE 540
+R G EQ E+ + P+P W RLE
Sbjct: 2224 KERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLE 2273
Score = 35.0 bits (79), Expect = 0.18
Identities = 63/281 (22%), Positives = 116/281 (41%), Gaps = 40/281 (14%)
Query: 286 LEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
LEER + A+ +++ H E ER+ +++ Q E+ + +KE Q
Sbjct: 1597 LEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD---L 1653
Query: 346 EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLRE------AQAELAQKLAE-- 397
E R + + + E++ + ++ +K LRE Q +L Q+ AE
Sbjct: 1654 ERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEG 1713
Query: 398 ----------IFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAP---REEAPGSCET 444
+ +K LR + + Q + L+E L++Q R+ S
Sbjct: 1714 KGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLL 1773
Query: 445 DDCKSRGLLGEAGGSEARDSAEQLRAELLQERL---------RGQE-QALRFEQERRTWQ 494
+ ++ + EAR+ E L+ + LQ +L R QE +AL+ EQ++ Q
Sbjct: 1774 SQREQEIVVLQQQLQEAREQGE-LKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQ 1832
Query: 495 EE--KERVLRYQREIQGGYMDMYRRNQALE---QELRALRE 530
EE KE+ Q ++ +M + R+ L+ ++ R L E
Sbjct: 1833 EERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE 1873
Score = 32.7 bits (73), Expect = 0.87
Identities = 60/262 (22%), Positives = 102/262 (38%), Gaps = 33/262 (12%)
Query: 278 GSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKEL 337
G +L+++ W E K L +RL ++T + + L Q Q E L KE
Sbjct: 411 GCQEAVNLLQQQHDQWEEEGKALR-QRLQKLTGERD----TLAGQTVDLQGEVDSLSKER 465
Query: 338 RAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISL----LKQQLREAQAELAQ 393
Q E R E+ W + + E+ L + Q E Q EL
Sbjct: 466 ELLQKAREELRQ---------QLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHL 516
Query: 394 KLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRS--LQEQAPREEAPGSCETDDCKSRG 451
+ E L+ L G A+ +EL+ LREA+ S L+ + R+E ++
Sbjct: 517 AVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQT-EVTAALARAEQ 575
Query: 452 LLGEAGGSE---------ARDSAEQLRA---ELLQERLRGQEQALRFEQERRTWQEEKER 499
+ E SE R +A +L A L +++ +Q L+ E+E ++ E
Sbjct: 576 SIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEA 635
Query: 500 VLRYQREIQGGYMDMYRRNQAL 521
+ + +Q + +R +AL
Sbjct: 636 AEQARNALQVDLAEAEKRREAL 657
Score = 32.3 bits (72), Expect = 1.1
Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 13/208 (6%)
Query: 286 LEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
L+E QR ELK + ++ E S LQ ++ + Q++ L+ +L AQ
Sbjct: 973 LQEAQR----ELKEAARQHRDDLAALQEESSSLLQDKMDL-QKQVEDLKSQLVAQDDSQR 1027
Query: 346 --EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKT 403
E L E R ++E E T + +Q+L Q + + E+ +L+
Sbjct: 1028 LVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQ 1087
Query: 404 QLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAP--GSCETDDCKSRGLLGEAGGSEA 461
++ ++ + + A++ LR+ V+ + +EA E + L EA
Sbjct: 1088 DMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEA 1147
Query: 462 RDSAEQLRAELLQERLRGQEQALRFEQE 489
+ + QLR + +L +AL EQ+
Sbjct: 1148 KAAQLQLRLRSTESQL----EALAAEQQ 1171
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 56.6 bits (135), Expect = 6e-08
Identities = 62/258 (24%), Positives = 110/258 (42%), Gaps = 32/258 (12%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPE 346
EER+ WL + E+ Q+ R + + Q Q+E+ RL++ LR++Q L
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL--- 538
Query: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQA--ELAQKLAEIFSLKTQ 404
R E+E R E K E L+Q+ RE + E ++ ++ + +
Sbjct: 539 --------------RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 405 LRGSRAQAQAQDAELVRL-REAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARD 463
R R + + ++ RL RE V L+++ RE+ E ++ + + LL E R
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR- 643
Query: 464 SAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQ 523
Q++LR ++Q R EQ + +EE+ R +RE + + + EQ
Sbjct: 644 ----------QQQLRREQQERR-EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 524 ELRALREPPTPWSPRLES 541
++ W +LES
Sbjct: 693 ARERIKSRIPKWQWQLES 710
Score = 56.6 bits (135), Expect = 6e-08
Identities = 68/253 (26%), Positives = 114/253 (45%), Gaps = 32/253 (12%)
Query: 287 EERQRLWLAELKRLY--VERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLA 344
EER++ E +R Y E+L + ++ R ER + + Q+ +R+ RK+ + QQ
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR----QERERQYRKDKKLQQ--- 968
Query: 345 PEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQ 404
E + G PE E++ R E + E LL++ E + Q+ + K +
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE---EREKRRRQEWERQYRKKDE 1025
Query: 405 LRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDS 464
L+ Q ++ E RL+E R +E+ ++ + LLGE + R
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQ----------EEEQLLGEERETRRRQE 1075
Query: 465 AE-QLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMY------RR 517
E Q R E +E + +EQ LR E E+R ++E+ER R + E+Q + RR
Sbjct: 1076 LERQYRKE--EELQQEEEQLLREEPEKRR-RQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 518 NQALEQELRALRE 530
Q LE++ R E
Sbjct: 1133 RQELERQYREEEE 1145
Score = 53.1 bits (126), Expect = 6e-07
Identities = 64/246 (26%), Positives = 107/246 (43%), Gaps = 41/246 (16%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGL 343
++ EE ++L E + L ER E Q+ +R R QL+ Q+E+RR ++E R +Q
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEE-EQQQQRLRREQQLR--RKQEEERREQQEERREQ-- 324
Query: 344 APEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAE--LAQKLAEIFSL 401
E R R +EE R + ++ E +QQLR Q E Q+L L
Sbjct: 325 -QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 402 KTQLRGSRAQAQAQDAELVRLREAVRSLQ---EQAPREEAPGSCETDDCKSRGLLGEAGG 458
+ + + R Q ++ +L R ++ R Q EQ R E
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE--------------------- 422
Query: 459 SEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRN 518
+ R E+ R E E+ R +++ R ++ERR W + +E R+++E RR
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE---------RRK 473
Query: 519 QALEQE 524
Q L+++
Sbjct: 474 QQLKRD 479
Score = 52.0 bits (123), Expect = 1e-06
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 22/226 (9%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEP--------RAPGTLPEADPSAR 361
Q+ ER E+ L+ + + +++Q R ++LR +Q L E R L R
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 362 PEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVR 421
+EE R E + E +Q+L+ Q E L + + R Q +D E R
Sbjct: 428 EQEEERHE---QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484
Query: 422 LREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQE 481
RE L+E+ RE+ + + + L E + Q E LQ+RLR ++
Sbjct: 485 -RERWLKLEEEERREQ-------QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 482 QALRFEQERRTW---QEEKERVLRYQREIQGGYMDMYRRNQALEQE 524
Q R ++ERR +EE++R+ + +RE + RR+Q L++E
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Score = 51.6 bits (122), Expect = 2e-06
Identities = 65/288 (22%), Positives = 116/288 (40%), Gaps = 30/288 (10%)
Query: 267 EELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMA 326
E R L +E G + E+ + L E + ERL + ++ E Q Q +
Sbjct: 123 EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE 182
Query: 327 QQEQRRLRKELRAQQG----------------------LAPEPRAPGTLPEADPSARPEE 364
++E+R ++L++ +G E + D + EE
Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
Query: 365 EARWEVCQKT--AEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRL 422
E W + E L+++ + Q EL ++ ++ L+ Q Q + Q + +R
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 423 REAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQ 482
+ +R QE+ RE+ E + R E + R E+ R +++LR +++
Sbjct: 303 EQQLRRKQEEERREQQEERREQQE--RREQQEERREQQLRREQEERR----EQQLRREQE 356
Query: 483 ALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
R EQ+ R QEE+ R + +RE Q RR Q L +E + RE
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Score = 50.8 bits (120), Expect = 3e-06
Identities = 79/303 (26%), Positives = 128/303 (42%), Gaps = 33/303 (10%)
Query: 256 EEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERS 315
EE G + +E +R L + + + + LE+R R E L+ +R E ++ ER
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDE--ELWRQR-QEWQEREERR 187
Query: 316 ERNLQLQLFMAQQ------EQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWE 369
QLQ + E++ R+EL + E + D + EEE W
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWR 247
Query: 370 VCQKTA--EISLLKQQLREAQAELAQKLAEIFSLKTQ-LRGSRAQAQAQ------DAELV 420
+ E L+++ + Q EL ++ ++ L+ Q LR R + + Q + +L
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 421 RLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGG---------SEARDSAEQLRAE 471
R +E R Q++ RE+ + ++ + + L E E +QLR E
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 472 LLQERLRGQ---EQALRFEQE-RRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRA 527
+ER Q EQ LR EQ+ RR Q +E+ LR RE Q RR Q L +E +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRREQQLRREQQL 425
Query: 528 LRE 530
RE
Sbjct: 426 RRE 428
Score = 50.8 bits (120), Expect = 3e-06
Identities = 67/262 (25%), Positives = 111/262 (42%), Gaps = 29/262 (11%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQL--QLFMAQQEQRRLRKEL---- 337
Q+ +ER+ L+ +R RL E + + ER Q Q+ Q++LR+E
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 338 ---------RAQQGLAPEPRAPGTLPEADPSARPEEEA--RWEVCQKTAEISLLKQQLRE 386
R +Q L + R L E R E E R + +K E L Q+ E
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
Query: 387 AQAELAQKLAEIFSLKTQLRGSRAQAQ-AQDAELVRLREAVRSLQEQAP-REEAPGSCET 444
Q ++ + + QLR + + Q+ + +R +E R +E+ R+E
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741
Query: 445 DDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQ 504
+ R +L E EQLR E +++LR QE+ +F +E + QE +E+ LR Q
Sbjct: 1742 RQERYRKILEE----------EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 505 REIQGGYMDMYRRNQALEQELR 526
+ + R + EQ+LR
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLR 1813
Score = 49.7 bits (117), Expect = 7e-06
Identities = 62/247 (25%), Positives = 110/247 (44%), Gaps = 16/247 (6%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPE 346
EER+ +L+R ER + ++ + ER Q QL Q+E+RR ++LR +Q L E
Sbjct: 332 EERRE---QQLRREQEERREQQLRREQEEERREQ-QLRREQEEERR-EQQLRREQQLRRE 386
Query: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLK--TQ 404
+ + R E++ R E + + +QQLR Q ++ E K +
Sbjct: 387 QQL-----RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 405 LRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDS 464
R R + + ++ RE EQ R++ + ++ + R L E E R+
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE--EERREQ 499
Query: 465 AEQLRAELLQERLRGQEQALRFEQERRTWQEE--KERVLRYQREIQGGYMDMYRRNQALE 522
E+ +L +E+ +EQ L+ ++E Q+ E+ LR ++E + + + LE
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
Query: 523 QELRALR 529
QE R R
Sbjct: 560 QERREQR 566
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/262 (25%), Positives = 111/262 (42%), Gaps = 34/262 (12%)
Query: 286 LEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
LEE Q+L E R + E+ +Q+ ER + QL Q+R RK L+ +Q L
Sbjct: 1488 LEEEQQLRRQERDRKFREQELR-SQEPERKFLEEEQQL----HRQQRQRKFLQEEQQLRR 1542
Query: 346 EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQ------LREAQAELAQKLAEIF 399
+ R + D R EE+ R Q+ E L +Q+ L E + ++ +
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLR----QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFM 1598
Query: 400 SLKTQLRGSRAQAQAQDAELVRLREAVRSLQE----QAPREEAPGSCETDDCKSRGLLGE 455
+ QLR Q Q + + RE + LQE Q R+E ++ + R E
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE 1658
Query: 456 AGGSEARDSAEQLRAELLQE-------------RLRGQEQALRFEQERRTWQEEKERVLR 502
RD + +LLQE + R +EQ LR ++ R + +E++++ R
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRR 1718
Query: 503 YQREIQGGYMDMYRRNQALEQE 524
+E++ + + + Q EQE
Sbjct: 1719 --QELERKFREEEQLRQETEQE 1738
Score = 47.0 bits (110), Expect = 4e-05
Identities = 70/255 (27%), Positives = 110/255 (43%), Gaps = 41/255 (16%)
Query: 287 EERQRLWLAELKRLY-----VERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQ 341
EER++ E +R Y +++ E + ER +R LQ + +R+ R+E QQ
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ-------ERERQYREEEELQQ 1058
Query: 342 G---LAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEI-SLLKQQLREAQAELAQKLAE 397
L E R E + R EEE + E Q E ++Q RE Q ++L +
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 398 IFSLKTQLRGSRAQAQAQDAEL-VRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEA 456
+ LR R + + Q+ E R E V+ +EQ REE K R
Sbjct: 1119 --EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE--------KRR------ 1162
Query: 457 GGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYR 516
++ Q R E +E + +EQ LR EQE+R ++E+ER R + E+Q
Sbjct: 1163 ----RQELERQYREE--EELQQEEEQLLREEQEKR--RQERERQYREEEELQRQKRKQRY 1214
Query: 517 RNQALEQELRALREP 531
R++ +L+ EP
Sbjct: 1215 RDEDQRSDLKWQWEP 1229
Score = 46.6 bits (109), Expect = 6e-05
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 24/254 (9%)
Query: 281 PFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQ 340
P + E+R+R K L E Q+ ER+++ + + + + ++RR +E R
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 341 Q----GLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLA 396
Q L E + A P+ +E+ R E +Q L+E + EL ++
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPAL--QEQLRKE-----------QQLLQEEEEELQREER 918
Query: 397 EIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEA 456
E + Q R R + Q Q E LRE R + + RE + K LLGE
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQLLREE-REKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 457 GGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYR 516
R E+ E +E L+ +E+ L E+ + ++E ER R + E+Q + R
Sbjct: 978 PEKRRRQEREKKYRE--EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
Query: 517 RNQALEQELRALRE 530
E+E R L+E
Sbjct: 1036 E----EREKRRLQE 1045
Score = 46.6 bits (109), Expect = 6e-05
Identities = 63/281 (22%), Positives = 112/281 (39%), Gaps = 37/281 (13%)
Query: 281 PFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQ 340
P + LEE Q+L + +R +++ ++ ++ +R ++EQ R +E +
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE---E 1569
Query: 341 QGLAPEPRAPGTLPEADPSARPEEEARW------------------EVCQKTAEISLLKQ 382
Q L+ + R E R E+E ++ E +K E L Q
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 383 QLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQE----QAPREEA 438
+ E Q ++ + + QLR + Q + + RE + LQE Q R+E
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 439 PGSCETDDC------KSRGLLGEAGGSEARD------SAEQLRAELLQERLRGQEQALRF 486
++ + R L E ++ EQLR E QE+LR QE+ +
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 487 EQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRA 527
+E + E +E+ LR Q + + R + EQ+LR+
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Score = 43.5 bits (101), Expect = 5e-04
Identities = 69/278 (24%), Positives = 123/278 (44%), Gaps = 39/278 (14%)
Query: 255 AEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAER 314
++E +L E EE +R + Q+L+ER+ L +R R E+ + E+
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ-EQ 1372
Query: 315 SERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEE--ARWEVCQ 372
+ L+ + + +QE R RK L+ +Q L + R + D R EE+ +R E +
Sbjct: 1373 GRKFLEEEQRLRRQE--RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 373 KTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQ 432
K E +QQ+R + E + + QLR R + ++ +L++ RE ++Q
Sbjct: 1431 KFREE---EQQVRRQERE-----RKFLEEEQQLRQERHRKFREEEQLLQERE-----EQQ 1477
Query: 433 APREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRT 492
R+E + R L E +QLR + + R EQ LR ++ R
Sbjct: 1478 LHRQE----------RDRKFLEEE---------QQLRRQERDRKFR--EQELRSQEPERK 1516
Query: 493 WQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
+ EE++++ R QR+ + + R Q Q+ R R+
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Score = 42.7 bits (99), Expect = 8e-04
Identities = 63/259 (24%), Positives = 114/259 (44%), Gaps = 23/259 (8%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGL 343
Q EE++R +EL+ ER H Q+ E R+ Q + A+++ R R+ L A+
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHR-QQQEEEQRRDFTWQ-WQAEEKSERGRQRLSAR--- 787
Query: 344 APEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKT 403
P + + R EE + E Q+ K+Q R + E ++L + +
Sbjct: 788 ------PPLREQRERQLRAEERQQRE--QRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 404 QLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARD 463
R RAQ ++ + ++ + R QEQ ++ E + + R L + +
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 464 SAEQLRAELLQERLRGQEQALRFEQER-------RTWQEEKERVLRYQREIQGGY--MDM 514
EQ + +E L+ +E+ R QE+ Q+E+E++LR +RE +
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 515 YRRNQALEQ-ELRALREPP 532
YR+++ L+Q E + L E P
Sbjct: 960 YRKDKKLQQKEEQLLGEEP 978
Score = 42.7 bits (99), Expect = 8e-04
Identities = 77/298 (25%), Positives = 126/298 (42%), Gaps = 52/298 (17%)
Query: 267 EELKRGLGDEDGSNPFTQVL--EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLF 324
+EL+R +E+ + L EE ++ EL+R Y E E+ Q+ E QL
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE-EELQQEEE--------QLL 1184
Query: 325 MAQQEQRRLRKE--LRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQ 382
+QE+RR +E R ++ L + R D R + + +WE +K + K
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRY---RDEDQRSDLKWQWEP-EKENAVRDNKV 1240
Query: 383 QLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDA---ELVRLREAVRSLQEQA----PR 435
+ + E ++L + +QLR ++Q Q + R RE R +Q P
Sbjct: 1241 YCKGRENEQFRQLED-----SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 436 EEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRA------------ELLQER----LRG 479
EE E + K R + R+ E+ R +LLQER LR
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 480 QE-------QALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
QE + LR +++ R + EE++R+ R +RE + + R Q EQ+LR R+
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Score = 42.7 bits (99), Expect = 8e-04
Identities = 63/269 (23%), Positives = 113/269 (42%), Gaps = 32/269 (11%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQR------RLRKEL 337
Q+ +ER R + E ++L ER + + ER + L+ + + +QE+ R RK
Sbjct: 1612 QLRQERDRKF-REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 338 RAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAE 397
+Q L E D R EE+ ++ ++ E L+++ + + EL +K E
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQ---QLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 398 IFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAG 457
+ QLR Q Q + E R R+ + Q + REE + D K R E
Sbjct: 1728 ----EEQLRQETEQEQLRRQE--RYRKILEEEQLRPEREEQQLRRQERDRKFR----EEE 1777
Query: 458 GSEARDSAEQLRAELLQERLRGQEQALRFEQERR-----------TWQEEKERVLRYQRE 506
+QLR++ + R +EQ LR E+E + W+EE+ ++ ++
Sbjct: 1778 QLRQEREEQQLRSQESDRKFREEEQ-LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Query: 507 IQGGYMDMYRRNQALEQELRALREPPTPW 535
++ YR + + ++ RE W
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELW 1865
Score = 42.7 bits (99), Expect = 8e-04
Identities = 66/258 (25%), Positives = 113/258 (43%), Gaps = 26/258 (10%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPE 346
+ER++ + R + E ++ Q+ E + Q + ++E+++LR++ R ++ L E
Sbjct: 1655 QEREQQLRHDRDRKFREE-EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEIS------LLKQQLR---EAQAELAQKLAE 397
+ E + R EE+ R E Q+ L ++QLR E Q Q+
Sbjct: 1714 QQL--RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 398 IFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAG 457
F + QLR R + Q + E R L+++ REE + D K R E
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE--REEQQLRPQQRDGKYRW---EEE 1826
Query: 458 GSEARDSAEQLRAEL-----LQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYM 512
+ + ++LR E +E+ QE++ R EQE WQEE+++ R Q +
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE--LWQEEEQK--RRQERERKLRE 1882
Query: 513 DMYRRNQALEQELRALRE 530
+ RR Q EQ R + E
Sbjct: 1883 EHIRRQQKEEQRHRQVGE 1900
Score = 40.0 bits (92), Expect = 0.005
Identities = 49/210 (23%), Positives = 93/210 (44%), Gaps = 23/210 (10%)
Query: 304 RLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPE 363
+L + + +S+++LQ L QQE+ R ++ R QQ PE + R E
Sbjct: 1252 QLEDSQLRDRQSQQDLQ-HLLGEQQERDREQERRRWQQ-------RDRHFPEEEQLEREE 1303
Query: 364 EEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLR 423
++ +K+ E KQ LRE + E ++ + R Q ++ + +R +
Sbjct: 1304 QKEAKRRDRKSQEE---KQLLREEREEKRRRQ----ETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 424 EAVRSLQEQAPREEAPGSCETDDC-------KSRGLLGEAGGSEARDSAEQLRAELLQER 476
E R +E+ R + G ++ + R L E ++ +QLR + +
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR-DRK 1415
Query: 477 LRGQEQALRFEQERRTWQEEKERVLRYQRE 506
R +EQ L ++ R ++EE+++V R +RE
Sbjct: 1416 FREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Score = 38.1 bits (87), Expect = 0.021
Identities = 76/311 (24%), Positives = 119/311 (38%), Gaps = 71/311 (22%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELR----- 338
Q+ E+Q LKR E E K E E + +L +QEQ R R + R
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705
Query: 339 ---------AQQGLAPEPRAP----GTLPEADPSARPEEEARWEVCQK------------ 373
Q + PR + + R E E +W+ ++
Sbjct: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Query: 374 -------------------TAEISLLKQQLREAQAELAQKLAEIF----SLKTQLRGSRA 410
+A L +Q+ R+ +AE Q+ + F K Q R R
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825
Query: 411 QAQ-----AQDAELVRLREAVRSLQE-----QAPREEAPGSCETDDCKSRGLLGEAGGSE 460
+ + ++ E ++ RE + LQE Q +E + D K R L E E
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE----E 881
Query: 461 ARDSAEQLRAE-LLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQ 519
+ L A+ LQE+LR ++Q L+ E+E +EE+E+ R ++E Q Y + + Q
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQ-EEEEELQREEREKRRRQEQERQ--YREEEQLQQ 938
Query: 520 ALEQELRALRE 530
EQ LR RE
Sbjct: 939 EEEQLLREERE 949
>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
sapiens]
Length = 1551
Score = 56.2 bits (134), Expect = 7e-08
Identities = 71/280 (25%), Positives = 110/280 (39%), Gaps = 42/280 (15%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGL 343
Q LE+ + EL R + E LH T E + ++Q + RL + LR + L
Sbjct: 420 QCLEQEK----VELSRKHQEALHAPTDHRELEQLRKEVQTL-----RDRLPEMLRDKASL 470
Query: 344 APEPRAPGTLPEADPSARPE---------------EEARWEVCQKTAEISLLKQQLREAQ 388
+ P P D R E + E+C+ + L Q+L+EAQ
Sbjct: 471 SQTDGPPAGSPGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQ 530
Query: 389 AELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ---EQAPREEAPGSCETD 445
A ++ +L +QL +RA + +A++ L V LQ EQ E +
Sbjct: 531 EREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHT 590
Query: 446 DCKSRGLLGEAGG---SEARDSAEQLRAELLQ---ERLRGQEQALRFEQERRTWQEEKER 499
++ G+ GG ++ R LR +L Q R G+E+AL QEE R
Sbjct: 591 ASETNGMGPPEGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEAL------CQLQEENRR 644
Query: 500 VLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRL 539
+ R Q ++ Q LE E RE + W +L
Sbjct: 645 LSREQERLEAELAQEQESKQRLEGE---RRETESNWEAQL 681
Score = 42.7 bits (99), Expect = 8e-04
Identities = 60/295 (20%), Positives = 124/295 (42%), Gaps = 39/295 (13%)
Query: 267 EELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMA 326
+EL R G ++ Q +ER+ ++ + L + ++A ++R L+ Q+
Sbjct: 510 QELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQ-----LEEARAAQRELEAQVSSL 564
Query: 327 QQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLRE 386
++ +L+ + + + + + T E + PE + Q E++ L++QL +
Sbjct: 565 SRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGP--QEAQLRKEVAALREQLEQ 622
Query: 387 AQAELAQKLAE-IFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCE-- 443
A + E + L+ + R + + +AEL + +E+ + L+ + E+ +
Sbjct: 623 AHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRETESNWEAQLA 682
Query: 444 ------TDDCKSRGLLGEAGGSEARDSAEQLRAELLQ-------------ERLRGQEQAL 484
D+ SRG L +A ++ + E LR Q RL+ E +
Sbjct: 683 DILSWVNDEKVSRGYL-QALATKMAEELESLRNVGTQTLPARPLDHQWKARRLQKMEASA 741
Query: 485 RFEQE---------RRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
R E + ++ QE +V Q + + + +++QAL+QEL LRE
Sbjct: 742 RLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQALQQELAMLRE 796
Score = 30.8 bits (68), Expect = 3.3
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 26/116 (22%)
Query: 353 LPEADPSARPEEEARWEVCQKTAEISLLKQQLRE--AQAELAQKLAEIFSLKTQLRGSRA 410
L + + SAR E ++ E AEI KQ L+E Q + AQ AE +L+ +
Sbjct: 734 LQKMEASARLELQSALE-----AEIRA-KQGLQERLTQVQEAQLQAE-----RRLQEAEK 782
Query: 411 QAQAQDAELVRLREAVRSLQEQAPREEAPG----------SCETDDCKSRGLLGEA 456
Q+QA EL LRE +R+ + P + P S E D K G+ GEA
Sbjct: 783 QSQALQQELAMLREELRA---RGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEA 835
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 55.8 bits (133), Expect = 1e-07
Identities = 64/261 (24%), Positives = 114/261 (43%), Gaps = 44/261 (16%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGL 343
++ ++ +++W E ERL E K E ++ Q ++ R KELR Q+
Sbjct: 249 KIRKQEEKMWRQE------ERLREQEGKMREQEEKMRRQ----EKRLREQEKELREQE-- 296
Query: 344 APEPRAPGTLPEADPSARPEEEARWEVCQKTAE-----------ISLLKQQLREAQAELA 392
E R L E + + +EE WE +K E + ++Q+RE + ++
Sbjct: 297 -KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 393 QKLAEIFSLKTQLRGSRAQAQAQD-----AELVRLREAVRSLQEQAPREEAPGSCETDDC 447
+ ++ +LR + + Q+ E ++ E +R +E+ REE E ++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE-REKKMREEEETMREQEEK 414
Query: 448 KSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEK----ERVLRY 503
+ + + EQ E Q+RL Q++ L +EQE+ QEEK E +R
Sbjct: 415 MQK---------QEENMWEQEEKEWQQQRLPEQKEKL-WEQEKMQEQEEKIWEQEEKIRD 464
Query: 504 QREIQGGYMDMYRRNQALEQE 524
Q E+ G M+R+ + EQE
Sbjct: 465 QEEMWGQEKKMWRQEKMREQE 485
Score = 49.3 bits (116), Expect = 9e-06
Identities = 50/254 (19%), Positives = 110/254 (43%), Gaps = 20/254 (7%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQ----- 341
++ Q++W E ER+ E ++ E ++ Q M QQE++ +R+E + Q+
Sbjct: 497 DQEQKMWDQE------ERMWEQDERLREKEERMREQKKMWQQEEK-MREEKKTQEQEKKT 549
Query: 342 -GLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAE--- 397
+ R + E + R EEE E +K E ++ E E +K+ E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 398 -IFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEA 456
++ + ++ + + Q+ E + + + +++ E + K R +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 457 GGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYR 516
G E + ++ + + +E++R QE+ +R ++E+ QEEK + Q E G +M
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK---MWGQEEKMWGQEEMRE 726
Query: 517 RNQALEQELRALRE 530
+ + + + ++E
Sbjct: 727 KEERIRDQKEKMQE 740
Score = 47.0 bits (110), Expect = 4e-05
Identities = 46/240 (19%), Positives = 108/240 (45%), Gaps = 24/240 (10%)
Query: 296 ELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPE 355
E L +E E ++N +LQ + E + +L ++ RA LP+
Sbjct: 167 ERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQ 226
Query: 356 ADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQ 415
+ EE R E ++LRE + ++ ++ +++ + +LR + + Q
Sbjct: 227 VQTNTLQEEMWRQE------------EELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 416 DAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQE 475
+ ++ R + +R QE+ RE+ E + + + ++ E++ + +E
Sbjct: 275 EEKMRRQEKRLRE-QEKELREQEKELREQKKLREQ-------EEQMQEQEEKMWEQ--EE 324
Query: 476 RLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPW 535
++R QE+ + + QE R W++EK+ + +++++ M+ +++ L ++ +RE W
Sbjct: 325 KMREQEEKM-WRQEERLWEQEKQ-MREQEQKMRDQEERMWEQDERLREKEERMREQEKMW 382
Score = 46.6 bits (109), Expect = 6e-05
Identities = 56/258 (21%), Positives = 111/258 (43%), Gaps = 24/258 (9%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNL-QLQLFMAQQEQRRLRKELRAQQG 342
Q+ E+ +++W E E++ E +K R E L + + M +QEQ+ +E R +
Sbjct: 311 QMQEQEEKMWEQE------EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE- 363
Query: 343 LAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLK 402
L E + R E+E WE +K E ++++ ++ + E + ++
Sbjct: 364 ------QDERLREKEERMR-EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
Query: 403 TQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAR 462
Q Q + ++ + RL E L EQ +E + K R G +
Sbjct: 417 KQEENMWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 463 DSAEQLRAELLQ-----ERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRR 517
E++R + Q E++R QEQ + ++QE R W++++ LR + E M+++
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKM-WDQEERMWEQDER--LREKEERMREQKKMWQQ 532
Query: 518 NQALEQELRALREPPTPW 535
+ + +E + + W
Sbjct: 533 EEKMREEKKTQEQEKKTW 550
Score = 45.4 bits (106), Expect = 1e-04
Identities = 47/246 (19%), Positives = 102/246 (41%), Gaps = 33/246 (13%)
Query: 264 ETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQL 323
E E K+ E+ + E+ ++ W E K ER+ E +K E ++ Q
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 324 FMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQ 383
Q+++ ++R++ + E + + +EE WE E + +Q+
Sbjct: 581 EKMQEQEEKMREQ-------------EEKMWEQEEKMQEQEEKMWE-----QEEKMWEQE 622
Query: 384 LREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCE 443
+ E + + E + Q Q+ ++ E +R +E+ +E +
Sbjct: 623 EEDKMQEQEEMMWE----------QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 672
Query: 444 TDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQE---EKERV 500
+ + + + + R+ E++R + +E++ GQE+ + ++E+ QE EKE
Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQ--EEKMWGQEEKMWGQEEKMWGQEEMREKEER 730
Query: 501 LRYQRE 506
+R Q+E
Sbjct: 731 IRDQKE 736
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 55.5 bits (132), Expect = 1e-07
Identities = 54/265 (20%), Positives = 123/265 (46%), Gaps = 26/265 (9%)
Query: 287 EERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
E+ ++W E K R E++ E +K R E + Q + ++E+R+ ++E+ Q+
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
Query: 346 EP----RAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSL 401
E R + E + R +EE W +K E ++++RE + ++ ++ +I
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE---QEEKIREQEEKMWRQEEKIREQ 543
Query: 402 KTQLRGSRA-----------QAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSR 450
+ R + Q Q+ ++ R E +R +E+ R+E + + + +
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603
Query: 451 GLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEK-----ERVLRYQR 505
+ R+ E+++ + +E++R QE+ +R ++E QEEK E++ +
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQ--EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 506 EIQGGYMDMYRRNQALEQELRALRE 530
++Q M+R+ + + ++ + +RE
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIRE 686
Score = 53.9 bits (128), Expect = 4e-07
Identities = 58/295 (19%), Positives = 126/295 (42%), Gaps = 27/295 (9%)
Query: 253 SSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELK-RLYVERLHEVTQK 311
+ A+ +G L +L+ + + + N Q EE+ +W E K + + E++ E +K
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK--MWRQEEKIQEWEEKIQEQEEK 322
Query: 312 AERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVC 371
E ++ +QE++ R+E + R + E + R +EE WE
Sbjct: 323 IREQEEKIR------EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 376
Query: 372 QKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLR--------GSRAQAQAQDAELVRLR 423
+K + + E EL +K+ E ++ Q + + Q Q+A++ R
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 424 EAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSA--------EQLRAELLQE 475
E +R +E+ +E + + + + E + ++ EQ +E
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 476 RLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
++ QE+ +R +QE + W++E E++ + +I+ M+R+ + + ++ RE
Sbjct: 497 KMHEQEEKIR-KQEEKVWRQE-EKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
Score = 47.0 bits (110), Expect = 4e-05
Identities = 43/242 (17%), Positives = 113/242 (46%), Gaps = 43/242 (17%)
Query: 286 LEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
+ E++ +W E K E++ E ++ E+ ++ + + + +QE++ R+E +
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK------- 592
Query: 346 EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQL 405
+ E + + +EE W+ ++++RE + ++ ++ +I + ++
Sbjct: 593 -------IREQEEKRQEQEEKMWK----------QEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 406 RGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSA 465
R Q Q+ ++ E + +E+ +E + + + R+
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE--------------KIREQE 681
Query: 466 EQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQAL-EQE 524
+++R + +E++R QE+ ++ EQE + W++E E++ + ++Q M R+ + + EQE
Sbjct: 682 KKIREQ--EEKIREQEEMMQ-EQEEKMWEQE-EKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Query: 525 LR 526
+R
Sbjct: 738 VR 739
Score = 34.7 bits (78), Expect = 0.23
Identities = 36/175 (20%), Positives = 83/175 (47%), Gaps = 17/175 (9%)
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKT--QLRGSRAQAQAQDAELVRLREAVRSLQEQAPR 435
++ ++L+E A+L +KL + S K+ QL + + + A+L+ ++ +++ + +
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 272
Query: 436 E----EAPGSCETDDCKSRGLLGEAGGSEARDSAEQL-----RAELLQERLRGQEQALRF 486
E A + ++ + L + + E++ + + +E++R QE+ +R
Sbjct: 273 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 487 EQERRTWQE----EKERVLRYQREIQGGYMDMYRRNQAL--EQELRALREPPTPW 535
++E+ QE EKE +R Q E+ + RR + + E+E + R+ W
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 55.5 bits (132), Expect = 1e-07
Identities = 77/293 (26%), Positives = 122/293 (41%), Gaps = 45/293 (15%)
Query: 242 PEPPPPYEFSCSSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLY 301
PEPP +E + E E + R L E +N +L RQ L E +
Sbjct: 150 PEPPAGPSKVEQLQDETNHLRKEL-ESVGRQLQAEVENNQMLSLLNRRQEERLREQE--- 205
Query: 302 VERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSAR 361
ERL E ++ E L Q ++++ RLR++ E R L E + R
Sbjct: 206 -ERLREQEERLREQEERLCEQEERLREQEERLREQ---------EER----LCEQEERLR 251
Query: 362 PEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVR 421
EE +C++ + +++LRE + L ++ + + +LR + Q+ R
Sbjct: 252 EHEE---RLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEE---R 305
Query: 422 LREAVRSL--QEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRG 479
LRE L QE+ RE+ CE + + L E E EQ R + QERL
Sbjct: 306 LREQEERLCEQEERLREQEERLCEQEKLPGQERLLE----EVEKLLEQERRQEEQERLLE 361
Query: 480 QEQALR-----FEQER------RTWQEEK----ERVLRYQREIQGGYMDMYRR 517
+E+ L EQER R WQ+E ER+ +R ++ G+ +Y +
Sbjct: 362 RERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQ 414
Score = 42.4 bits (98), Expect = 0.001
Identities = 63/239 (26%), Positives = 98/239 (41%), Gaps = 32/239 (13%)
Query: 315 SERNLQLQLFMAQQEQRRLRK-ELRAQQGLAPEPRAPGT----LPEADPSARPEEEARWE 369
S+ + ++ + Q+ R L K + + + LAPEP A + L + R E E+
Sbjct: 119 SKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGR 178
Query: 370 VCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSL 429
Q E + + L Q E ++ E +LR + + Q+ L E +R
Sbjct: 179 QLQAEVENNQMLSLLNRRQEERLREQEE------RLREQEERLREQEERLCEQEERLRE- 231
Query: 430 QEQAPREEAPGSCETDD---------CKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQ 480
QE+ RE+ CE ++ C+ L E E R ++ R +ERL Q
Sbjct: 232 QEERLREQEERLCEQEERLREHEERLCEQEERLCE---QEERLREQEERLHEQEERLCEQ 288
Query: 481 EQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRL 539
E+ LR ++ER QEE+ LR Q E + R EQE R + P RL
Sbjct: 289 EERLREQEERLCEQEER---LREQEERLCEQEERLR-----EQEERLCEQEKLPGQERL 339
Score = 37.0 bits (84), Expect = 0.046
Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 18/146 (12%)
Query: 370 VCQKTAEISLLKQQLREA---QAELAQKLAE-IFSLKTQLRGSRA-QAQAQDAELVRLRE 424
+ Q T I+ L + +E + L QKL +F LK Q A + A +++ +L++
Sbjct: 105 ISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQD 164
Query: 425 AVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQAL 484
L+++ E ++ + LL R E+LR + +ERLR QE+ L
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLN-------RRQEERLREQ--EERLREQEERL 215
Query: 485 RFEQERRTWQEEK----ERVLRYQRE 506
R ++ER QEE+ E LR Q E
Sbjct: 216 REQEERLCEQEERLREQEERLREQEE 241
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 55.5 bits (132), Expect = 1e-07
Identities = 60/230 (26%), Positives = 104/230 (45%), Gaps = 22/230 (9%)
Query: 326 AQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLR 385
AQQ RL++E + +G R PGT +A S +V ++ L+++LR
Sbjct: 743 AQQVLARLQEENQQLRGSLSPCREPGTSLKAPASP--------QVAALEQDLGKLEEELR 794
Query: 386 EAQAELAQKLAEIFSLKT---QLRGSRAQAQAQDAELVRLREAVRS---LQEQAPREEAP 439
QA ++ K EI LK Q A+ +A++A +R E R Q QA +E
Sbjct: 795 AVQATMSGKSQEIGKLKQLLYQATEEVAELRAREAASLRQHEKTRGSLVAQAQAWGQELK 854
Query: 440 GSCE--TDDCKSRGLLGEAGGSEARDSAEQLRAELLQER----LRGQEQALRFEQERRTW 493
E C+ G L EA E R S + QER +RG+ + +FE+
Sbjct: 855 ALLEKYNTACREVGRLREAVAEERRRSGDLAAQAAEQERQASEMRGRSE--QFEKTAELL 912
Query: 494 QEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLESSK 543
+E+ E ++ R+ + ++ ++ + L +E+ A+R + +L+ S+
Sbjct: 913 KEKMEHLIGACRDKEAKIKELLKKLEQLSEEVLAIRGENARLALQLQDSQ 962
Score = 30.4 bits (67), Expect = 4.3
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
Query: 330 QRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEA-------------RWEVCQKTAE 376
QR ++ A Q EP+A G+ P++ A PEEE RW+ ++ +
Sbjct: 250 QRLVQHPDLASQASPSEPQA-GSPPKSSWRAEPEEEQEEKEDEDPCSEEWRWKYEEERRK 308
Query: 377 ISLLKQQLREAQAELAQKLAEIFSLKTQLR 406
+ L+Q+L + E + A L+ Q+R
Sbjct: 309 VVRLEQELVQKTEECKTQAAAYLDLENQIR 338
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 55.1 bits (131), Expect = 2e-07
Identities = 99/389 (25%), Positives = 151/389 (38%), Gaps = 64/389 (16%)
Query: 202 GTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAV 261
G ++L GG+ + + +EA A L+ E + + AE+
Sbjct: 1111 GRKEEELQAALARAEDEGGARAQLLKSLREA--QAALAEAQEDLESERVARTKAEKQRRD 1168
Query: 262 LPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVE--RLHEVTQKAERSERNL 319
L E E L+ L D S Q L ++ + ELK+ E R+HE + R
Sbjct: 1169 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1228
Query: 320 QLQLFMAQQEQRRLRK---------------ELRA---------QQGLAPEPRAPGTLPE 355
L Q EQ R K ELRA Q+G R L E
Sbjct: 1229 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQE 1288
Query: 356 ADPSARPEEEARWEVCQKT----AEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSR-- 409
A E AR E +K AE+ + L EA+++ + E+ S + QL ++
Sbjct: 1289 VQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1348
Query: 410 ------------AQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCK----SRGLL 453
++ +A +AE LRE + +E A RE A +T + R
Sbjct: 1349 LQEETRAKLALGSRVRAMEAEAAGLREQLE--EEAAARERAGRELQTAQAQLSEWRRRQE 1406
Query: 454 GEAGGSEARDSAEQ---LRAELLQERLRGQEQAL-RFEQERRTWQEEKERV---LRYQRE 506
EAG EA + A + AE L +RL + + + R E+ RR Q+E + L QR+
Sbjct: 1407 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1466
Query: 507 IQGGYMDMYRR-NQALEQE----LRALRE 530
+ R+ +Q L +E LRA+ E
Sbjct: 1467 LVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1495
Score = 48.1 bits (113), Expect = 2e-05
Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 45/301 (14%)
Query: 253 SSAEEMGAVLPETCEELKRG--LGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQ 310
SS +++G ++ EL+R + ++ ++ QV E L AE +L +E VT
Sbjct: 1543 SSKDDVG----KSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE----VTV 1594
Query: 311 KAERS--ERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPE----- 363
+A ++ ER+LQ + ++ +R+L K+LR + E R TL A AR +
Sbjct: 1595 QALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVA---ARKKLEGEL 1651
Query: 364 EEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKT-------QLRGSRAQAQAQD 416
EE + ++ +QLR+ QA++ + E+ +T Q R S + + +
Sbjct: 1652 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1711
Query: 417 AELVRLREAVRS-----LQEQAPREEAPGSCETDDC-------KSRGLLGEAGGSEARDS 464
AE++RL+E + + Q Q R+E + + R L G G E
Sbjct: 1712 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1771
Query: 465 AEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQE 524
EQ +ELL +R R L + E T + ER + + + G + R+ Q L
Sbjct: 1772 EEQSNSELLNDRYR----KLLLQVESLTTELSAER--SFSAKAESGRQQLERQIQELRGR 1825
Query: 525 L 525
L
Sbjct: 1826 L 1826
Score = 46.6 bits (109), Expect = 6e-05
Identities = 71/277 (25%), Positives = 113/277 (40%), Gaps = 28/277 (10%)
Query: 255 AEEMGAVLPETCEELKRGLG---DEDGSNP-FTQVLEERQRLWLAELKRLYVERLHEVTQ 310
AEE+ A L EEL+ L DE G+ + L E Q + L ER+
Sbjct: 1103 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART-- 1160
Query: 311 KAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV 370
KAE+ R+L +L + E AQQ L + T + EEE R
Sbjct: 1161 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVT----ELKKTLEEETRIH- 1215
Query: 371 CQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
A + L+Q+ +A ELA++L + K +R A +AE+ LR + SL
Sbjct: 1216 ---EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRL---ALEAEVSELRAELSSL- 1268
Query: 431 EQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQER 490
Q R+E + + + + G AG E+ RAE ++ R Q + E
Sbjct: 1269 -QTARQEGEQRRRRLELQLQEVQGRAG------DGERARAEAAEKLQRAQAE---LENVS 1318
Query: 491 RTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRA 527
E + + +R +E+ ++ + L++E RA
Sbjct: 1319 GALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1355
Score = 40.4 bits (93), Expect = 0.004
Identities = 61/273 (22%), Positives = 122/273 (44%), Gaps = 30/273 (10%)
Query: 262 LPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQL 321
L + +EL+ L E+G+ Q L+ + A++K+ + L Q ++ S+ L
Sbjct: 973 LQQHIQELEAHLEAEEGAR---QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1029
Query: 322 QLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV----CQKTAEI 377
+ +A+ + +E + + + T+ + + R EE+ R E+ + E
Sbjct: 1030 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1089
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQD---AELVR-LREAVRSLQEQA 433
S L++Q+ E Q + A++ + +L+ + A+A+ + A+L++ LREA +L E
Sbjct: 1090 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAE-- 1147
Query: 434 PREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTW 493
+D +S + + RD E+L E L+ L + +QE R+
Sbjct: 1148 ---------AQEDLESERVARTKAEKQRRDLGEEL--EALRGELEDTLDSTNAQQELRSK 1196
Query: 494 QEEKERVLRYQREIQGGYMDMYRRNQALEQELR 526
+E++ L+ E + R ++A QELR
Sbjct: 1197 REQEVTELKKTLE------EETRIHEAAVQELR 1223
Score = 36.6 bits (83), Expect = 0.060
Identities = 62/311 (19%), Positives = 123/311 (39%), Gaps = 60/311 (19%)
Query: 267 EELKR-----GLGDEDGSNPFTQVLEERQRLWL-AELKRLYVERLHEVTQKAERSERNLQ 320
EELK G G E+ ++ + + LW E R E + +++E+ + L+
Sbjct: 1652 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1711
Query: 321 LQLFMAQQE---QRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEI 377
++ Q+E R R++ + + + A G L +A A EE+ + E +
Sbjct: 1712 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA---AILEEKRQLE-----GRL 1763
Query: 378 SLLKQQLREAQAE-------LAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
L+++L E Q+ + L ++ SL T+L R+ + ++ +L ++ L+
Sbjct: 1764 GQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELR 1823
Query: 431 EQAPREEAPGSCE-------------------TDDCKSRGLLGEAGG------------- 458
+ E+A + + R L G+
Sbjct: 1824 GRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQV 1883
Query: 459 SEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRN 518
E R A+QLR +L + LR ++ + E+ +EE R +R +Q D+
Sbjct: 1884 EEERRVADQLRDQLEKGNLRVKQLKRQLEEA----EEEASRAQAGRRRLQRELEDVTESA 1939
Query: 519 QALEQELRALR 529
+++ +E+ LR
Sbjct: 1940 ESMNREVTTLR 1950
Score = 35.8 bits (81), Expect = 0.10
Identities = 35/175 (20%), Positives = 75/175 (42%), Gaps = 26/175 (14%)
Query: 253 SSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKA 312
+ AE L +EL+ LG+ED R ++ +A L+ +L + ++
Sbjct: 1806 AKAESGRQQLERQIQELRGRLGEEDAG------ARARHKMTIAALE----SKLAQAEEQL 1855
Query: 313 ERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQ 372
E+ R L + ++ ++RL++ + + + R ++ R ++ +
Sbjct: 1856 EQETRERILSGKLVRRAEKRLKE----------------VVLQVEEERRVADQLRDQLEK 1899
Query: 373 KTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVR 427
+ LK+QL EA+ E ++ A L+ +L A++ + E+ LR +R
Sbjct: 1900 GNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 55.1 bits (131), Expect = 2e-07
Identities = 99/389 (25%), Positives = 151/389 (38%), Gaps = 64/389 (16%)
Query: 202 GTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAV 261
G ++L GG+ + + +EA A L+ E + + AE+
Sbjct: 1103 GRKEEELQAALARAEDEGGARAQLLKSLREA--QAALAEAQEDLESERVARTKAEKQRRD 1160
Query: 262 LPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVE--RLHEVTQKAERSERNL 319
L E E L+ L D S Q L ++ + ELK+ E R+HE + R
Sbjct: 1161 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1220
Query: 320 QLQLFMAQQEQRRLRK---------------ELRA---------QQGLAPEPRAPGTLPE 355
L Q EQ R K ELRA Q+G R L E
Sbjct: 1221 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQE 1280
Query: 356 ADPSARPEEEARWEVCQKT----AEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSR-- 409
A E AR E +K AE+ + L EA+++ + E+ S + QL ++
Sbjct: 1281 VQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1340
Query: 410 ------------AQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCK----SRGLL 453
++ +A +AE LRE + +E A RE A +T + R
Sbjct: 1341 LQEETRAKLALGSRVRAMEAEAAGLREQLE--EEAAARERAGRELQTAQAQLSEWRRRQE 1398
Query: 454 GEAGGSEARDSAEQ---LRAELLQERLRGQEQAL-RFEQERRTWQEEKERV---LRYQRE 506
EAG EA + A + AE L +RL + + + R E+ RR Q+E + L QR+
Sbjct: 1399 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1458
Query: 507 IQGGYMDMYRR-NQALEQE----LRALRE 530
+ R+ +Q L +E LRA+ E
Sbjct: 1459 LVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1487
Score = 48.1 bits (113), Expect = 2e-05
Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 45/301 (14%)
Query: 253 SSAEEMGAVLPETCEELKRG--LGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQ 310
SS +++G ++ EL+R + ++ ++ QV E L AE +L +E VT
Sbjct: 1535 SSKDDVG----KSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE----VTV 1586
Query: 311 KAERS--ERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPE----- 363
+A ++ ER+LQ + ++ +R+L K+LR + E R TL A AR +
Sbjct: 1587 QALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVA---ARKKLEGEL 1643
Query: 364 EEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKT-------QLRGSRAQAQAQD 416
EE + ++ +QLR+ QA++ + E+ +T Q R S + + +
Sbjct: 1644 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1703
Query: 417 AELVRLREAVRS-----LQEQAPREEAPGSCETDDC-------KSRGLLGEAGGSEARDS 464
AE++RL+E + + Q Q R+E + + R L G G E
Sbjct: 1704 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1763
Query: 465 AEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQE 524
EQ +ELL +R R L + E T + ER + + + G + R+ Q L
Sbjct: 1764 EEQSNSELLNDRYR----KLLLQVESLTTELSAER--SFSAKAESGRQQLERQIQELRGR 1817
Query: 525 L 525
L
Sbjct: 1818 L 1818
Score = 46.6 bits (109), Expect = 6e-05
Identities = 71/277 (25%), Positives = 113/277 (40%), Gaps = 28/277 (10%)
Query: 255 AEEMGAVLPETCEELKRGLG---DEDGSNP-FTQVLEERQRLWLAELKRLYVERLHEVTQ 310
AEE+ A L EEL+ L DE G+ + L E Q + L ER+
Sbjct: 1095 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART-- 1152
Query: 311 KAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV 370
KAE+ R+L +L + E AQQ L + T + EEE R
Sbjct: 1153 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVT----ELKKTLEEETRIH- 1207
Query: 371 CQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
A + L+Q+ +A ELA++L + K +R A +AE+ LR + SL
Sbjct: 1208 ---EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRL---ALEAEVSELRAELSSL- 1260
Query: 431 EQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQER 490
Q R+E + + + + G AG E+ RAE ++ R Q + E
Sbjct: 1261 -QTARQEGEQRRRRLELQLQEVQGRAG------DGERARAEAAEKLQRAQAE---LENVS 1310
Query: 491 RTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRA 527
E + + +R +E+ ++ + L++E RA
Sbjct: 1311 GALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1347
Score = 40.4 bits (93), Expect = 0.004
Identities = 61/273 (22%), Positives = 122/273 (44%), Gaps = 30/273 (10%)
Query: 262 LPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQL 321
L + +EL+ L E+G+ Q L+ + A++K+ + L Q ++ S+ L
Sbjct: 965 LQQHIQELEAHLEAEEGAR---QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1021
Query: 322 QLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV----CQKTAEI 377
+ +A+ + +E + + + T+ + + R EE+ R E+ + E
Sbjct: 1022 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1081
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQD---AELVR-LREAVRSLQEQA 433
S L++Q+ E Q + A++ + +L+ + A+A+ + A+L++ LREA +L E
Sbjct: 1082 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAE-- 1139
Query: 434 PREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTW 493
+D +S + + RD E+L E L+ L + +QE R+
Sbjct: 1140 ---------AQEDLESERVARTKAEKQRRDLGEEL--EALRGELEDTLDSTNAQQELRSK 1188
Query: 494 QEEKERVLRYQREIQGGYMDMYRRNQALEQELR 526
+E++ L+ E + R ++A QELR
Sbjct: 1189 REQEVTELKKTLE------EETRIHEAAVQELR 1215
Score = 36.6 bits (83), Expect = 0.060
Identities = 62/311 (19%), Positives = 123/311 (39%), Gaps = 60/311 (19%)
Query: 267 EELKR-----GLGDEDGSNPFTQVLEERQRLWL-AELKRLYVERLHEVTQKAERSERNLQ 320
EELK G G E+ ++ + + LW E R E + +++E+ + L+
Sbjct: 1644 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1703
Query: 321 LQLFMAQQE---QRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEI 377
++ Q+E R R++ + + + A G L +A A EE+ + E +
Sbjct: 1704 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA---AILEEKRQLE-----GRL 1755
Query: 378 SLLKQQLREAQAE-------LAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
L+++L E Q+ + L ++ SL T+L R+ + ++ +L ++ L+
Sbjct: 1756 GQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELR 1815
Query: 431 EQAPREEAPGSCE-------------------TDDCKSRGLLGEAGG------------- 458
+ E+A + + R L G+
Sbjct: 1816 GRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQV 1875
Query: 459 SEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRN 518
E R A+QLR +L + LR ++ + E+ +EE R +R +Q D+
Sbjct: 1876 EEERRVADQLRDQLEKGNLRVKQLKRQLEEA----EEEASRAQAGRRRLQRELEDVTESA 1931
Query: 519 QALEQELRALR 529
+++ +E+ LR
Sbjct: 1932 ESMNREVTTLR 1942
Score = 35.8 bits (81), Expect = 0.10
Identities = 35/175 (20%), Positives = 75/175 (42%), Gaps = 26/175 (14%)
Query: 253 SSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKA 312
+ AE L +EL+ LG+ED R ++ +A L+ +L + ++
Sbjct: 1798 AKAESGRQQLERQIQELRGRLGEEDAG------ARARHKMTIAALE----SKLAQAEEQL 1847
Query: 313 ERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQ 372
E+ R L + ++ ++RL++ + + + R ++ R ++ +
Sbjct: 1848 EQETRERILSGKLVRRAEKRLKE----------------VVLQVEEERRVADQLRDQLEK 1891
Query: 373 KTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVR 427
+ LK+QL EA+ E ++ A L+ +L A++ + E+ LR +R
Sbjct: 1892 GNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 55.1 bits (131), Expect = 2e-07
Identities = 99/389 (25%), Positives = 151/389 (38%), Gaps = 64/389 (16%)
Query: 202 GTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAV 261
G ++L GG+ + + +EA A L+ E + + AE+
Sbjct: 1144 GRKEEELQAALARAEDEGGARAQLLKSLREA--QAALAEAQEDLESERVARTKAEKQRRD 1201
Query: 262 LPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVE--RLHEVTQKAERSERNL 319
L E E L+ L D S Q L ++ + ELK+ E R+HE + R
Sbjct: 1202 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1261
Query: 320 QLQLFMAQQEQRRLRK---------------ELRA---------QQGLAPEPRAPGTLPE 355
L Q EQ R K ELRA Q+G R L E
Sbjct: 1262 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQE 1321
Query: 356 ADPSARPEEEARWEVCQKT----AEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSR-- 409
A E AR E +K AE+ + L EA+++ + E+ S + QL ++
Sbjct: 1322 VQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1381
Query: 410 ------------AQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCK----SRGLL 453
++ +A +AE LRE + +E A RE A +T + R
Sbjct: 1382 LQEETRAKLALGSRVRAMEAEAAGLREQLE--EEAAARERAGRELQTAQAQLSEWRRRQE 1439
Query: 454 GEAGGSEARDSAEQ---LRAELLQERLRGQEQAL-RFEQERRTWQEEKERV---LRYQRE 506
EAG EA + A + AE L +RL + + + R E+ RR Q+E + L QR+
Sbjct: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1499
Query: 507 IQGGYMDMYRR-NQALEQE----LRALRE 530
+ R+ +Q L +E LRA+ E
Sbjct: 1500 LVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
Score = 48.1 bits (113), Expect = 2e-05
Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 45/301 (14%)
Query: 253 SSAEEMGAVLPETCEELKRG--LGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQ 310
SS +++G ++ EL+R + ++ ++ QV E L AE +L +E VT
Sbjct: 1576 SSKDDVG----KSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE----VTV 1627
Query: 311 KAERS--ERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPE----- 363
+A ++ ER+LQ + ++ +R+L K+LR + E R TL A AR +
Sbjct: 1628 QALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVA---ARKKLEGEL 1684
Query: 364 EEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKT-------QLRGSRAQAQAQD 416
EE + ++ +QLR+ QA++ + E+ +T Q R S + + +
Sbjct: 1685 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1744
Query: 417 AELVRLREAVRS-----LQEQAPREEAPGSCETDDC-------KSRGLLGEAGGSEARDS 464
AE++RL+E + + Q Q R+E + + R L G G E
Sbjct: 1745 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1804
Query: 465 AEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQE 524
EQ +ELL +R R L + E T + ER + + + G + R+ Q L
Sbjct: 1805 EEQSNSELLNDRYR----KLLLQVESLTTELSAER--SFSAKAESGRQQLERQIQELRGR 1858
Query: 525 L 525
L
Sbjct: 1859 L 1859
Score = 46.6 bits (109), Expect = 6e-05
Identities = 71/277 (25%), Positives = 113/277 (40%), Gaps = 28/277 (10%)
Query: 255 AEEMGAVLPETCEELKRGLG---DEDGSNP-FTQVLEERQRLWLAELKRLYVERLHEVTQ 310
AEE+ A L EEL+ L DE G+ + L E Q + L ER+
Sbjct: 1136 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART-- 1193
Query: 311 KAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV 370
KAE+ R+L +L + E AQQ L + T + EEE R
Sbjct: 1194 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVT----ELKKTLEEETRIH- 1248
Query: 371 CQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
A + L+Q+ +A ELA++L + K +R A +AE+ LR + SL
Sbjct: 1249 ---EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRL---ALEAEVSELRAELSSL- 1301
Query: 431 EQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQER 490
Q R+E + + + + G AG E+ RAE ++ R Q + E
Sbjct: 1302 -QTARQEGEQRRRRLELQLQEVQGRAG------DGERARAEAAEKLQRAQAE---LENVS 1351
Query: 491 RTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRA 527
E + + +R +E+ ++ + L++E RA
Sbjct: 1352 GALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1388
Score = 40.4 bits (93), Expect = 0.004
Identities = 61/273 (22%), Positives = 122/273 (44%), Gaps = 30/273 (10%)
Query: 262 LPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQL 321
L + +EL+ L E+G+ Q L+ + A++K+ + L Q ++ S+ L
Sbjct: 1006 LQQHIQELEAHLEAEEGAR---QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1062
Query: 322 QLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV----CQKTAEI 377
+ +A+ + +E + + + T+ + + R EE+ R E+ + E
Sbjct: 1063 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1122
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQD---AELVR-LREAVRSLQEQA 433
S L++Q+ E Q + A++ + +L+ + A+A+ + A+L++ LREA +L E
Sbjct: 1123 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAE-- 1180
Query: 434 PREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTW 493
+D +S + + RD E+L E L+ L + +QE R+
Sbjct: 1181 ---------AQEDLESERVARTKAEKQRRDLGEEL--EALRGELEDTLDSTNAQQELRSK 1229
Query: 494 QEEKERVLRYQREIQGGYMDMYRRNQALEQELR 526
+E++ L+ E + R ++A QELR
Sbjct: 1230 REQEVTELKKTLE------EETRIHEAAVQELR 1256
Score = 36.6 bits (83), Expect = 0.060
Identities = 62/311 (19%), Positives = 123/311 (39%), Gaps = 60/311 (19%)
Query: 267 EELKR-----GLGDEDGSNPFTQVLEERQRLWL-AELKRLYVERLHEVTQKAERSERNLQ 320
EELK G G E+ ++ + + LW E R E + +++E+ + L+
Sbjct: 1685 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1744
Query: 321 LQLFMAQQE---QRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEI 377
++ Q+E R R++ + + + A G L +A A EE+ + E +
Sbjct: 1745 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA---AILEEKRQLE-----GRL 1796
Query: 378 SLLKQQLREAQAE-------LAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
L+++L E Q+ + L ++ SL T+L R+ + ++ +L ++ L+
Sbjct: 1797 GQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELR 1856
Query: 431 EQAPREEAPGSCE-------------------TDDCKSRGLLGEAGG------------- 458
+ E+A + + R L G+
Sbjct: 1857 GRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQV 1916
Query: 459 SEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRN 518
E R A+QLR +L + LR ++ + E+ +EE R +R +Q D+
Sbjct: 1917 EEERRVADQLRDQLEKGNLRVKQLKRQLEEA----EEEASRAQAGRRRLQRELEDVTESA 1972
Query: 519 QALEQELRALR 529
+++ +E+ LR
Sbjct: 1973 ESMNREVTTLR 1983
Score = 35.8 bits (81), Expect = 0.10
Identities = 35/175 (20%), Positives = 75/175 (42%), Gaps = 26/175 (14%)
Query: 253 SSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKA 312
+ AE L +EL+ LG+ED R ++ +A L+ +L + ++
Sbjct: 1839 AKAESGRQQLERQIQELRGRLGEEDAG------ARARHKMTIAALE----SKLAQAEEQL 1888
Query: 313 ERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQ 372
E+ R L + ++ ++RL++ + + + R ++ R ++ +
Sbjct: 1889 EQETRERILSGKLVRRAEKRLKE----------------VVLQVEEERRVADQLRDQLEK 1932
Query: 373 KTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVR 427
+ LK+QL EA+ E ++ A L+ +L A++ + E+ LR +R
Sbjct: 1933 GNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 54.7 bits (130), Expect = 2e-07
Identities = 52/248 (20%), Positives = 117/248 (47%), Gaps = 34/248 (13%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGL 343
++ E+ +++W E K E++ E ++ E+ E Q + Q+E R ++++ Q+ +
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490
Query: 344 APEP----RAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIF 399
+ R + + + R +EE W +K E ++++RE Q E ++ E+
Sbjct: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE---QEEKIRE-QEEKIREQEEMM 546
Query: 400 SLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGS 459
+ + G + + + ++ R E +R QE+ RE+
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIRE-QEEKIREQK--------------------E 585
Query: 460 EARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQ 519
+ R+ E++ + +E++R QE+ ++ EQE + W++E E++ + ++Q M R+ +
Sbjct: 586 KIREQEEKIWEQ--EEKIREQEEMMQ-EQEEKMWEQE-EKMCEQEEKMQEQEEKMRRQEE 641
Query: 520 AL-EQELR 526
+ EQE+R
Sbjct: 642 KMWEQEVR 649
Score = 53.1 bits (126), Expect = 6e-07
Identities = 61/296 (20%), Positives = 129/296 (43%), Gaps = 44/296 (14%)
Query: 253 SSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKA 312
+ A+ +G L +L+ + + + N Q EE+ +W E E++ E +K
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK--MWRQE------EKIQEWEEKI 316
Query: 313 ERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQ 372
+ E ++ Q +++ R +++R Q+ + + E + R +EE WE +
Sbjct: 317 QEQEEKIREQ----EEKIREQEEKMRRQEEM---------MWEKEEKMRRQEEMMWEKEE 363
Query: 373 KTAEISLLKQQLREAQAELAQKLAEIFSLKTQLR--------GSRAQAQAQDAELVRLRE 424
K + + + E EL +K+ E ++ Q + + Q Q+A++ R E
Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 423
Query: 425 AVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQAL 484
+R +E+ +E + + + + E E R E++ + +E++R QE+
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIRE---EEKRQEQEEMWRQ--EEKIREQEEIW 478
Query: 485 R-----FEQERRTWQEEK-----ERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
R EQE+ QEEK E++ + +I+ M+R+ + + ++ +RE
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE 534
Score = 49.3 bits (116), Expect = 9e-06
Identities = 49/239 (20%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 276 EDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRK 335
E+ + + E++++ E KR E++ E ++ E+ + + + + +QE++ +
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Query: 336 ELRAQQGLAPEPRAPGTLPEADPSARPEEEARW---EVCQKTAEISLLKQQLREAQAELA 392
E + + E + + R E+E W E ++ EI K+++ E Q ++
Sbjct: 436 EKKMWR---QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE-QEKIR 491
Query: 393 QKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGL 452
++ +++ + ++ + + Q+ ++ R E +R QE+ RE+ E ++
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE-QEEKIREQEEKIREQEEMMQEQ- 549
Query: 453 LGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEK----ERVLRYQREI 507
E G + EQ + +E++R QE+ +R ++E+ QEEK E +R Q E+
Sbjct: 550 -EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEM 607
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/224 (21%), Positives = 109/224 (48%), Gaps = 24/224 (10%)
Query: 290 QRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPR 348
+ +W E K R E++HE + E+ E+ +QE+ ++R++ + Q+ A R
Sbjct: 370 EMMWEKEEKIRELEEKMHEQEKIREQEEK---------RQEEEKIREQEKRQEQEAKMWR 420
Query: 349 APGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGS 408
+ E + R +E+ W +K E ++++RE E Q+ E++ + ++R
Sbjct: 421 QEEKIREQEEKIREQEKKMWRQEEKIHE----QEKIREE--EKRQEQEEMWRQEEKIR-- 472
Query: 409 RAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQL 468
+ + E + +E +R +E+ R+E + + + + + R+ E++
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532
Query: 469 RAELLQERLRGQEQALRFEQERRTWQEEK----ERVLRYQREIQ 508
R + +E++R QE+ ++ ++E+ QEEK E++ R + +I+
Sbjct: 533 REQ--EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR 574
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Query: 284 QVLEERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLF-MAQQEQRRLRKE-LRAQ 340
++ E+ +++W E K R E++ E +K E +Q Q M +QE++ +E +R Q
Sbjct: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ 569
Query: 341 QGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAE-IF 399
+ E + E R +EE WE +K E + Q+ E E +K+ E
Sbjct: 570 EEKIREQEEK--IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 400 SLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEA 438
++ Q R Q + + VRLR+ +QE EA
Sbjct: 628 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 34.7 bits (78), Expect = 0.23
Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 25/168 (14%)
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVR-LREAVRSLQEQAPRE 436
++ ++L+E A+L +KL + S K+++ Q EL R L A L +Q +
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEI-------QLNVKELKRKLERAKLLLPQQQLQA 265
Query: 437 EAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELL----------QERLRGQEQALRF 486
EA + S L + +E + Q + E + +E+++ QE+ +R
Sbjct: 266 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 487 EQERRTWQEEKERVLRYQREIQGGYMDMYRRNQAL----EQELRALRE 530
++E+ QEEK +R Q E+ + RR + + E+++R L E
Sbjct: 326 QEEKIREQEEK---MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 53.9 bits (128), Expect = 4e-07
Identities = 80/337 (23%), Positives = 134/337 (39%), Gaps = 57/337 (16%)
Query: 209 SSSLGHLNHLGGSLDRAS----QGPKEAGPPAVLSCLP--------------EPPPPYEF 250
+SS HLNH S+ AS GP PA + P PPPP +
Sbjct: 1316 TSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHY 1375
Query: 251 SCS-SAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVT 309
+ M LP + GL + + EE QR + E RL ER
Sbjct: 1376 AGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEER----- 1430
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSA----RPEEE 365
+ +R E+ +L Q L AQQ +P P TL + +P+++
Sbjct: 1431 -ERKRREQERKLGQMRTQSLNPAPFSPLTAQQ---MKPEKPSTLQRPQETVIRELQPQQQ 1486
Query: 366 ARWEVCQKTAEISLLKQQL------------REAQAELAQK----LAEIFSLKTQLRGSR 409
R + I++ K++L R+A+ +L ++ + ++ S + Q S+
Sbjct: 1487 PRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSK 1546
Query: 410 AQAQAQDAELVRLREAV------RSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSE-AR 462
A++++ RLR+ + + LQE ++E E DD + ++ AR
Sbjct: 1547 PDRSAEESD--RLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1604
Query: 463 DSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKER 499
D + + +L + R R E R E+ERR +EE+ +
Sbjct: 1605 DEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK 1641
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 53.1 bits (126), Expect = 6e-07
Identities = 93/389 (23%), Positives = 153/389 (39%), Gaps = 75/389 (19%)
Query: 209 SSSLGHLNHLGGSLDRAS----QGPKEAGPPAVLSCLP--------------EPPPPYEF 250
+SS HLNH S+ AS GP PA + P PPPP +
Sbjct: 1315 TSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHY 1374
Query: 251 SCS-SAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVT 309
+ M LP + GL + + EE QR + E RL ER
Sbjct: 1375 AGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEER----- 1429
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSA----RPEEE 365
+ +R E+ +L Q L AQQ +P P TL + +P+++
Sbjct: 1430 -ERKRREQERKLGQMRTQSLNPAPFSPLTAQQ---MKPEKPSTLQRPQETVIRELQPQQQ 1485
Query: 366 ARWEVCQKTAEISLLKQQL------------REAQAELAQK----LAEIFSLKTQLRGSR 409
R + I++ K++L R+A+ +L ++ + ++ S + Q S+
Sbjct: 1486 PRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSK 1545
Query: 410 AQAQAQDAELVRLREAV------RSLQEQAPREEAPGSCETDDC-------------KSR 450
A++++ RLR+ + + LQE ++E E DD ++R
Sbjct: 1546 PDRSAEESD--RLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1603
Query: 451 GLLGEAGGSEARDSAEQLRAELLQE-RLRGQEQALRFEQERRTWQEEK-ERVLRYQREIQ 508
+ + E+ R + L+E R R E R E+ERR +EE+ +R +R +
Sbjct: 1604 TAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQE 1663
Query: 509 GGY---MDMYRRNQALEQELRALREPPTP 534
GY ++ RR Q ++ R L EP P
Sbjct: 1664 EGYYSRLEAERRRQH-DEAARRLLEPEAP 1691
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 52.8 bits (125), Expect = 8e-07
Identities = 58/256 (22%), Positives = 107/256 (41%), Gaps = 41/256 (16%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQE----QRRLRKELRAQQG 342
E+ +++W E K +RL E +K E+ + + Q+E Q ++ K+ + Q+
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 343 LA---PEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIF 399
+ R ++ E + R EEE E +K E Q+ E E +K+ E
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE-- 759
Query: 400 SLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGS 459
+ + E RL E L E +E E ++
Sbjct: 760 ------------QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE------------- 794
Query: 460 EARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEK-----ERVLRYQREIQGGYMDM 514
+ RD E++R + +E++RGQE+ +R ++E+ QEEK E++ + ++ G M
Sbjct: 795 KMRDQEEKMRGQ--EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 515 YRRNQALEQELRALRE 530
+ Q E+++R E
Sbjct: 853 EEKMQGQEEKMREQEE 868
Score = 52.4 bits (124), Expect = 1e-06
Identities = 63/271 (23%), Positives = 116/271 (42%), Gaps = 44/271 (16%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGL 343
++ ++ +++W E ERL E K E + Q ++ R KELR Q+
Sbjct: 287 KIRKQEEKMWRQE------ERLREQEGKMREQEEKMWRQ----EKRLREQEKELREQE-- 334
Query: 344 APEPRAPGTLPEADPSARPEEEARWEVCQKTAE-----------ISLLKQQLREAQAELA 392
E R L E + + +EE WE +K E + ++Q+RE + ++
Sbjct: 335 -KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 393 QKLAEIFSLKTQLRGSRAQAQAQD---AELVRLREAVR-SLQEQAPREEAPGSCETDDCK 448
+ ++ +LR + + Q+ ++ ++RE + QE+ R++ E + +
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 449 SRGLLGEAGGSEARDSAEQLR-----------AELLQERLRGQEQALRFEQERRTWQEEK 497
R R+ E+++ E Q+RL Q++ L +EQE+ QEEK
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL-WEQEKMQEQEEK 512
Query: 498 ----ERVLRYQREIQGGYMDMYRRNQALEQE 524
E +R Q E+ G M+R+ + EQE
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/250 (25%), Positives = 111/250 (44%), Gaps = 54/250 (21%)
Query: 287 EERQRLWLAELKRLYVE-RLHEVTQKAERSERNL-QLQLFMAQQEQRRLRKELRAQQGLA 344
E +++L LAE ++ ++ + E+ +K ER++ L Q+Q Q+E R +ELR Q+
Sbjct: 229 ELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI 288
Query: 345 PEP-----RAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIF 399
+ R L E + R +EE W +++LRE + EL ++ E+
Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQ----------EKRLREQEKELREQEKELR 338
Query: 400 SLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGS 459
K +LR Q Q Q+ ++ E +R +E+ R+E
Sbjct: 339 EQK-ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE---------------------- 375
Query: 460 EARDSAEQLRAELLQERLRGQEQALRFEQERRTWQE-----EKERVLRYQREIQGGYMDM 514
E+L + ++++R QEQ +R +QE R W++ EKE +R Q ++ M
Sbjct: 376 ------ERLWEQ--EKQMREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQVEKM 426
Query: 515 YRRNQALEQE 524
+ EQE
Sbjct: 427 REEKKMQEQE 436
Score = 51.2 bits (121), Expect = 2e-06
Identities = 43/218 (19%), Positives = 102/218 (46%), Gaps = 6/218 (2%)
Query: 286 LEERQRLWLAELKRLYVERLHEVTQKAERS---ERNLQLQLFMAQQEQRRLRKELRAQQG 342
++E++++ E K E++ + TQ+ E+ + ++ + M ++E++ +E ++
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Query: 343 LAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREA-QAELAQKLAEIFSL 401
+ E + +EE WE +K E L +Q + + E Q+ +I+
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 402 KTQLRGSRAQAQAQDAELVRLREAVRSLQEQ--APREEAPGSCETDDCKSRGLLGEAGGS 459
+ ++R + + Q+ ++ E +R +E+ E+ G E + + G+
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 460 EARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEK 497
E + ++ + +E++RGQE+ +R ++E+ QEEK
Sbjct: 853 EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 45.4 bits (106), Expect = 1e-04
Identities = 51/255 (20%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPE 346
E+ +RL E + E++ E +K R E+ +Q Q + ++ ++++E R ++
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKM-REEKKMQEQEKKTRDQEEKMQEEERIREREKKM 459
Query: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLRE--AQAELAQKLAEIFSLKTQ 404
T+ E + + +EE WE +K + L +Q + Q ++ ++ +I+ + +
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 405 LRGSRAQAQAQDAELVR---LREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEA 461
+R + + Q+ ++ R +RE + EQ + D + + +
Sbjct: 520 IR-DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Query: 462 RDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQAL 521
D E++R E ER+R +E+ +R E+E +E++E++ + ++Q M+ + + +
Sbjct: 579 WDQEEKMREE---ERMREREKKMREEEE--MMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 522 -EQELRALREPPTPW 535
EQE + + W
Sbjct: 634 QEQEEKMWEQEEKMW 648
Score = 42.7 bits (99), Expect = 8e-04
Identities = 46/248 (18%), Positives = 102/248 (41%), Gaps = 22/248 (8%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPE 346
E++++LW E ++ E +K E ++ Q M QE++ R+E +Q
Sbjct: 495 EQKEKLWEQE-------KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ----- 542
Query: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLR 406
+ E + R +E+ W+ ++ + + Q+ + + +K+ E ++ + +
Sbjct: 543 ---EDQMWEQEEKMRDQEQKMWDQEERMEKKT---QEQEKKTWDQEEKMREEERMREREK 596
Query: 407 GSRAQAQAQDAELVRLREAVRSLQEQAPR----EEAPGSCETDDCKSRGLLGEAGGSEAR 462
R + + + +++E +QEQ + EE E + + E
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWE 656
Query: 463 DSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALE 522
+ E L E + QEQ EQE + W++EK ++E + + R +++
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Query: 523 QELRALRE 530
+ + +RE
Sbjct: 717 EREKKMRE 724
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/235 (21%), Positives = 100/235 (42%), Gaps = 52/235 (22%)
Query: 296 ELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPE 355
E L +E E ++N +LQ + E + +L ++ RA LP+
Sbjct: 205 ERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQ 264
Query: 356 ADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQ 415
+ EE R E ++LRE + ++ ++ +++ + +LR + + Q
Sbjct: 265 VQTNTLQEEMWRQE------------EELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 312
Query: 416 DAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQE 475
+ ++ R QE+ RE+ E R+ ++LR Q+
Sbjct: 313 EEKMWR--------QEKRLREQE--------------------KELREQEKELRE---QK 341
Query: 476 RLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
LR QE+ ++ EQE + W++E++ +R Q E M+R+ + L ++ + +RE
Sbjct: 342 ELREQEEQMQ-EQEEKMWEQEEK--MREQEE------KMWRQEERLWEQEKQMRE 387
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.4 bits (124), Expect = 1e-06
Identities = 47/231 (20%), Positives = 104/231 (45%), Gaps = 26/231 (11%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWE 369
+K R E +Q +QE++ +EL+ ++ R + E + R +E+ W
Sbjct: 297 EKMWRQEEKIQ------EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWR 350
Query: 370 VCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSL 429
++++RE + ++ ++ +++ + ++R + Q Q+ E+ R E +R
Sbjct: 351 Q----------EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 430 QEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALR---- 485
+E+ R+E E K R + E ++ + L+E ++ QE+ LR
Sbjct: 401 EEK--RQEKMWRQEK---KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 486 -FEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPW 535
++E QE++E++ R + +IQ +R+ + L+QE + + W
Sbjct: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/254 (22%), Positives = 111/254 (43%), Gaps = 38/254 (14%)
Query: 284 QVLEERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQR---RLRKELRA 339
++ E+ ++W E K R E++ E +K R E ++ Q Q+++ R +++R
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 340 QQGLAPEP--RAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAE 397
Q+ E R + E D R +EE W +K E+ + Q E E+ +K+ E
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 398 IFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAG 457
+ Q Q+ ++ R E ++ +E+ R+E LL +
Sbjct: 460 ----------EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK-------------LLKQ-- 494
Query: 458 GSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKER---VLRYQREIQGGYMDM 514
E + ++ + +E++ QE+ ++ ++E+ QEEK R V +Q+E + +
Sbjct: 495 --EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK--MQEQ 550
Query: 515 YRRNQALEQELRAL 528
R Q LE+ L L
Sbjct: 551 EVRLQELEERLGKL 564
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/184 (22%), Positives = 81/184 (44%), Gaps = 21/184 (11%)
Query: 287 EERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
EE +++ E K + E++ E +K R E+ L+ + + +QE++ R+E + +
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 346 EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFS----- 400
+ + R +E W+ +K E + Q+L E +L QK AE+
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK-AELLGGAGRE 577
Query: 401 ------------LKTQLRGSRAQA--QAQDAELVRLREAVRSLQEQAPREEAPGSCETDD 446
L+ +L+ AQ+ Q QD L++ V + Q+ A +EA SC +
Sbjct: 578 SGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRK 637
Query: 447 CKSR 450
+++
Sbjct: 638 LRAK 641
Score = 32.7 bits (73), Expect = 0.87
Identities = 34/159 (21%), Positives = 73/159 (45%), Gaps = 31/159 (19%)
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREE 437
++ ++L+E AEL +KL + S K+++ Q +D + +L A L +Q + E
Sbjct: 210 TITDEELKEKNAELQEKLRLVESEKSEI-----QLNVKDLKR-KLERAQLLLPQQQLQVE 263
Query: 438 APGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTW---- 493
A + G E + + +L+A++ + L L +QE + W
Sbjct: 264 A----------------DRLGKELQSVSAKLQAQVEENELWN---LLNQQQEEKMWRQEE 304
Query: 494 --QEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
QE++E++ + +I+ M+R+ + + ++ +RE
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.4 bits (124), Expect = 1e-06
Identities = 47/231 (20%), Positives = 104/231 (45%), Gaps = 26/231 (11%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWE 369
+K R E +Q +QE++ +EL+ ++ R + E + R +E+ W
Sbjct: 297 EKMWRQEEKIQ------EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWR 350
Query: 370 VCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSL 429
++++RE + ++ ++ +++ + ++R + Q Q+ E+ R E +R
Sbjct: 351 Q----------EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 430 QEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALR---- 485
+E+ R+E E K R + E ++ + L+E ++ QE+ LR
Sbjct: 401 EEK--RQEKMWRQEK---KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 486 -FEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPW 535
++E QE++E++ R + +IQ +R+ + L+QE + + W
Sbjct: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/254 (22%), Positives = 111/254 (43%), Gaps = 38/254 (14%)
Query: 284 QVLEERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQR---RLRKELRA 339
++ E+ ++W E K R E++ E +K R E ++ Q Q+++ R +++R
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 340 QQGLAPEP--RAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAE 397
Q+ E R + E D R +EE W +K E+ + Q E E+ +K+ E
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 398 IFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAG 457
+ Q Q+ ++ R E ++ +E+ R+E LL +
Sbjct: 460 ----------EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK-------------LLKQ-- 494
Query: 458 GSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKER---VLRYQREIQGGYMDM 514
E + ++ + +E++ QE+ ++ ++E+ QEEK R V +Q+E + +
Sbjct: 495 --EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK--MQEQ 550
Query: 515 YRRNQALEQELRAL 528
R Q LE+ L L
Sbjct: 551 EVRLQELEERLGKL 564
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/184 (22%), Positives = 81/184 (44%), Gaps = 21/184 (11%)
Query: 287 EERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
EE +++ E K + E++ E +K R E+ L+ + + +QE++ R+E + +
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 346 EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFS----- 400
+ + R +E W+ +K E + Q+L E +L QK AE+
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK-AELLGGAGRE 577
Query: 401 ------------LKTQLRGSRAQA--QAQDAELVRLREAVRSLQEQAPREEAPGSCETDD 446
L+ +L+ AQ+ Q QD L++ V + Q+ A +EA SC +
Sbjct: 578 SGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRK 637
Query: 447 CKSR 450
+++
Sbjct: 638 LRAK 641
Score = 32.7 bits (73), Expect = 0.87
Identities = 34/159 (21%), Positives = 73/159 (45%), Gaps = 31/159 (19%)
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREE 437
++ ++L+E AEL +KL + S K+++ Q +D + +L A L +Q + E
Sbjct: 210 TITDEELKEKNAELQEKLRLVESEKSEI-----QLNVKDLKR-KLERAQLLLPQQQLQVE 263
Query: 438 APGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTW---- 493
A + G E + + +L+A++ + L L +QE + W
Sbjct: 264 A----------------DRLGKELQSVSAKLQAQVEENELWN---LLNQQQEEKMWRQEE 304
Query: 494 --QEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
QE++E++ + +I+ M+R+ + + ++ +RE
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/244 (20%), Positives = 117/244 (47%), Gaps = 24/244 (9%)
Query: 288 ERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPE 346
+ + +W E K R E++HE + E+ E+ +QE+ ++R++ + Q+ A
Sbjct: 335 QEEMMWEKEEKIRELEEKMHEQEKIREQEEK---------RQEEEKIREQEKRQEQEAKM 385
Query: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLR 406
R + E + R +EE E +K E ++++ E + E+ ++ ++ + ++R
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGE---QEEKMWEQEEEMQEQEEKMRRQEEKIR 442
Query: 407 GSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAE 466
+ + Q+ ++RE +QEQ EE G E C+ + E + R E
Sbjct: 443 EQEKKIREQEE---KIREQEEMMQEQ---EEKMGEQEGKMCEQEAKMQEQE-EKMRRQEE 495
Query: 467 QLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELR 526
++R + ++++R QE+ +R ++E QE++E++ + ++ M + + + ++
Sbjct: 496 KIREQ--EKKIREQEEKIREQEEMM--QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Query: 527 ALRE 530
+RE
Sbjct: 552 KMRE 555
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/297 (18%), Positives = 133/297 (44%), Gaps = 27/297 (9%)
Query: 253 SSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELK-RLYVERLHEVTQK 311
+ A+ +G L +L+ + + + N Q EE+ +W E K + E++ E +K
Sbjct: 253 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK--MWRQEEKIQEREEKIQEQEEK 310
Query: 312 AERSERNLQLQLFMAQQEQRRLRKELRAQ-------QGLAPEPRAPGTLPEADPSARPEE 364
E ++ Q M +++ ++R++ + L + + E + + EE
Sbjct: 311 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 370
Query: 365 EARWEVCQKTAEISLLKQQ---------LREAQAELAQKLAEIFSLKTQLRGSRAQAQAQ 415
+ R + ++ E + +Q+ +RE + + ++ ++ + ++ + Q Q
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ 430
Query: 416 DAELVRLREAVRSLQEQAPREEAPGSCETDDC--KSRGLLGEAGGSEARDSAEQLRAELL 473
+ ++ R E +R QE+ RE+ E ++ + +GE G A+ E
Sbjct: 431 EEKMRRQEEKIRE-QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE-- 487
Query: 474 QERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
E++R QE+ +R EQE++ +E++E++ + +Q M+ + + + ++ ++E
Sbjct: 488 -EKMRRQEEKIR-EQEKKI-REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Score = 42.7 bits (99), Expect = 8e-04
Identities = 48/212 (22%), Positives = 88/212 (41%), Gaps = 26/212 (12%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLF-MAQQEQRRLRKELRAQQGLAP 345
E+ ++W E E++ E +K E +Q Q M +QE++ +E Q+
Sbjct: 380 EQEAKMWRQE------EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK 433
Query: 346 EPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQL 405
R + E + R +EE K E + Q+ E E K+ E
Sbjct: 434 MRRQEEKIREQEKKIREQEE-------KIREQEEMMQEQEEKMGEQEGKMCE-------- 478
Query: 406 RGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSA 465
A+ Q Q+ ++ R E +R QE+ RE+ E ++ + E +
Sbjct: 479 --QEAKMQEQEEKMRRQEEKIRE-QEKKIREQEEKIREQEEMMQEQE-EKMWEQEEKMCE 534
Query: 466 EQLRAELLQERLRGQEQALRFEQERRTWQEEK 497
++ + + +E++R QE+ +R ++ R QEEK
Sbjct: 535 QEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 34.3 bits (77), Expect = 0.30
Identities = 39/161 (24%), Positives = 77/161 (47%), Gaps = 18/161 (11%)
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVR-LREAVRSLQEQAPRE 436
++ ++L+E A+L +KL + S K+++ Q EL R L A L +Q +
Sbjct: 201 TITDEELKEKNAKLQEKLQLVESEKSEI-------QLNVKELKRKLERAKLLLPQQQLQA 253
Query: 437 EAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELL---QERLRGQEQALRFEQERRTW 493
EA + S L + +E + Q + E + +E+++ +E+ ++ ++E+
Sbjct: 254 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Query: 494 QEEKERVLRYQREIQGGYMDMYRRNQAL----EQELRALRE 530
QEEK +R Q E+ + RR + + E+++R L E
Sbjct: 314 QEEK---MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351
>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
Length = 1133
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/247 (22%), Positives = 99/247 (40%), Gaps = 27/247 (10%)
Query: 290 QRLWLAELKRLYVERLHEVTQKAERSERNLQLQL--FMAQQEQRRLRKELRAQQGLAPEP 347
+R L K +E V K R L + F AQQ+ + R E A++ L +
Sbjct: 853 ERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKERAEREAERALQVDT 912
Query: 348 RAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRG 407
+ GTL + ++ AE+ + +LR + +LA + A + + +LR
Sbjct: 913 QREGTLIS--------------LAKEQAELKIRASELRAEEKQLAAERAALEQERQELRL 958
Query: 408 SRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQ 467
+ + A + E V S+ + A + G L EA +A A
Sbjct: 959 EKERINATALRVKLRAEEVESMSKVASEKYEEG---------ERALREAQQVQAEQQARL 1009
Query: 468 LRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRA 527
+ QERLR QEQ QE + +++ ++ R ++++ + ++ R Q ++
Sbjct: 1010 QAVQQQQERLRKQEQ--HMHQEHLSLAQQRLQLDRARQDLPSSLVGLFPRAQGPAASSQS 1067
Query: 528 LREPPTP 534
PP P
Sbjct: 1068 ALMPPAP 1074
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/228 (21%), Positives = 107/228 (46%), Gaps = 14/228 (6%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEE----E 365
++ E R + Q+ + + R ++R Q+G E G + E + R +E E
Sbjct: 90 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVRE 147
Query: 366 ARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREA 425
+V ++ ++ + Q+RE + ++ ++ ++ + Q+R Q Q+ ++ E
Sbjct: 148 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ 207
Query: 426 VRSLQEQAPR-EEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQAL 484
+ +EQ + EE G E K +GE E + ++ + + +E++R QE+ +
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE---QEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 485 RFEQERRTWQEEK--ERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
R ++E+ QEE+ ++ + ++E Q G + R Q E+++R E
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ--EEQMREQEE 310
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/218 (20%), Positives = 101/218 (46%), Gaps = 18/218 (8%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEA--- 366
Q E+ E+ + + M +QE++ ++E + Q+ + + E + R +EE
Sbjct: 221 QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
Query: 367 RWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAV 426
+ E ++ + ++Q+RE + ++ ++ ++ + Q+R Q Q+ ++ +E +
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Query: 427 RSLQEQA-PREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALR 485
+EQ +EE G E K + R EQ+R + +E++R QE+ +R
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQE--------EQVRKQEEQMRKQ--EEQMRKQEEQMR 390
Query: 486 FEQERRTWQE----EKERVLRYQREIQGGYMDMYRRNQ 519
++E+ Q+ E++ +R Q E G + R+ +
Sbjct: 391 KQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Score = 36.2 bits (82), Expect = 0.079
Identities = 39/214 (18%), Positives = 90/214 (42%), Gaps = 10/214 (4%)
Query: 313 ERSERNLQLQ--LFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV 370
E E+N +LQ L + + E+ ++ ++ + + P LP+ E + R
Sbjct: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIP--LPQEGQVREQEGQVR--- 62
Query: 371 CQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQ 430
++ ++ + Q+RE + ++ ++ ++ + Q+R Q + Q+ ++ VR +
Sbjct: 63 -EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
Query: 431 EQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQER 490
Q +E G + + R G+ E + ++ + + ++R QE +R ++ +
Sbjct: 122 GQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 179
Query: 491 RTWQEEKERVLRYQREIQGGYMDMYRRNQALEQE 524
QE + R Q Q G M ++E
Sbjct: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
Score = 34.7 bits (78), Expect = 0.23
Identities = 44/214 (20%), Positives = 91/214 (42%), Gaps = 21/214 (9%)
Query: 325 MAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQL 384
M +QE++ ++E + + + + E + + +EE +V ++ ++ ++Q+
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE---QVQKQEEQMRKQEEQM 264
Query: 385 REAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCET 444
RE + ++ ++ ++ K Q + + + E +R +E QE+ RE+ E
Sbjct: 265 REQEEQMREQEEQMLKQKEQTE--QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ 322
Query: 445 DDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRG--------QEQALRFEQERRTWQEE 496
++ G E + EQ QE G QE+ +R ++E+ QEE
Sbjct: 323 EE--QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE 380
Query: 497 ----KERVLRYQREIQGGYMDMY--RRNQALEQE 524
+E +R Q E G + ++ Q EQE
Sbjct: 381 QMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE 414
Score = 29.6 bits (65), Expect = 7.4
Identities = 21/134 (15%), Positives = 62/134 (46%), Gaps = 4/134 (2%)
Query: 303 ERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARP 362
E+ + Q E+ E+ + + M +QE++ +E + ++ + + E
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 363 EEEARW----EVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAE 418
++E W ++ ++ ++ ++Q+R+ + ++ ++ ++ + Q+R Q Q +
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402
Query: 419 LVRLREAVRSLQEQ 432
+ +E +R +EQ
Sbjct: 403 MGEQKEQMREQEEQ 416
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 51.2 bits (121), Expect = 2e-06
Identities = 58/278 (20%), Positives = 124/278 (44%), Gaps = 28/278 (10%)
Query: 253 SSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKA 312
+ A+ +G L +L+ + + + N Q EE+ +W E E++ E +K
Sbjct: 326 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK--MWRQE------EKIQEWEEKI 377
Query: 313 ERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQ 372
+ E ++ Q +++ R +++R Q+ + + E + R +EE WE +
Sbjct: 378 QEQEEKIREQ----EEKIREQEEKMRRQEEM---------MWEKEEKMRRQEEMMWEKEE 424
Query: 373 KTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQ 432
K + + E EL +K+ E ++ Q + + + ++ E + +EA QE+
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 433 APREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRT 492
RE+ E ++ R E + + E+ R E QE + QE+ +R ++E
Sbjct: 485 KIREQEEKIREQEEKMWR--QEEKIHEQEKIREEEKRQE--QEEMWRQEEKIREQEE--I 538
Query: 493 WQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
W+ +KE++ + +I+ M+R+ + + + +RE
Sbjct: 539 WR-QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE 575
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/262 (18%), Positives = 116/262 (44%), Gaps = 48/262 (18%)
Query: 287 EERQRLWLAELK-RLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAP 345
E+ ++W E K R E++ E +K R E + Q + ++E+R+ ++E+ Q+
Sbjct: 474 EQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 533
Query: 346 EP----RAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSL 401
E R + E + R +EE W ++++ + + ++ ++ +++
Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKMWRQ----------EEKMHDQEEKIREQEEKVWRQ 583
Query: 402 KTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEA 461
+ ++R + + Q+ E +R +E + QE+ E+ CE ++
Sbjct: 584 EEKIREQEEKIREQE-EKIREQEEMTQEQEEKMGEQEEKMCEQEE--------------- 627
Query: 462 RDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQAL 521
+ + +E++R QE+ +R EQE++ +E++E++ + +Q M+ + + +
Sbjct: 628 -------KMQEQEEKMRRQEEKIR-EQEKKI-REQEEKIREQEEMMQEQEEKMWEQEEKM 678
Query: 522 --------EQELRALREPPTPW 535
EQE + R+ W
Sbjct: 679 CEQEEKMQEQEEKMRRQEEKMW 700
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/234 (19%), Positives = 109/234 (46%), Gaps = 13/234 (5%)
Query: 284 QVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGL 343
++ E+ +++W E K E++ E ++ E+ E Q + Q+E R ++++ Q+
Sbjct: 492 KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEK 551
Query: 344 APEP-----RAPGTLPEADPSARPEEEARWEVCQKTAE----ISLLKQQLREAQAELAQK 394
+ R + + + R +EE W +K E I ++++RE + ++
Sbjct: 552 IRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ 611
Query: 395 LAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLG 454
++ + ++ + Q Q+ ++ R E +R QE+ RE+ E ++
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE-QEKKIREQEEKIREQEEMMQEQE-E 669
Query: 455 EAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQ 508
+ E + ++ + + +E++R QE+ + +EQE R Q+E E++ +Q ++
Sbjct: 670 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKM-WEQEVRLRQQE-EKMQEHQEHLE 721
Score = 35.0 bits (79), Expect = 0.18
Identities = 36/172 (20%), Positives = 83/172 (48%), Gaps = 19/172 (11%)
Query: 378 SLLKQQLREAQAELAQKLAEIFSLKT--QLRGSRAQAQAQDAELVRLREAVRSLQEQAPR 435
++ ++L+E A+L +KL + S K+ QL + + + A+L+ ++ +++ + +
Sbjct: 274 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 333
Query: 436 E----EAPGSCETDDCKSRGLLGEAGGSEARDSAEQL-----RAELLQERLRGQEQALRF 486
E A + ++ + L + + E++ + + +E++R QE+ +R
Sbjct: 334 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 393
Query: 487 EQERRTWQE----EKERVLRYQREIQGGYMDMYRRNQAL----EQELRALRE 530
++E+ QE EKE +R Q E+ + RR + + E+++R L E
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 50.8 bits (120), Expect = 3e-06
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 21/226 (9%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQ--QGLA 344
EE +R L++ VER +V E ++R+ + +L Q +R E AQ + L
Sbjct: 1546 EEAER----RLRQAEVERARQVQVALETAQRSAEAEL----QSKRASFAEKTAQLERSLQ 1597
Query: 345 PEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQ 404
E A L E + R +++A E ++ AE L + QL+ +A + AE + +
Sbjct: 1598 EEHVAVAQLRE-EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1656
Query: 405 LRGSRAQAQAQDAELVRLREAVR--SLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAR 462
L + A+ Q ++AE REA R +EQA R+ E + K R L G ++ R
Sbjct: 1657 LAQAEAEKQKEEAE----REARRRGKAEEQAVRQRELAEQELE--KQRQL--AEGTAQQR 1708
Query: 463 DSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQ 508
+AEQ L E +G++Q E+E Q E + ++E++
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELE 1754
Score = 49.7 bits (117), Expect = 7e-06
Identities = 55/234 (23%), Positives = 96/234 (41%), Gaps = 22/234 (9%)
Query: 297 LKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEA 356
L+R+ E Q+AE ER +++ A E++R E AQ E A
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVE---AALEKQRQLAEAHAQAKAQAEREAKELQQRM 1397
Query: 357 DPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQD 416
EEA + Q+ I QQLR+ S + +++ QA+A +
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEELQQLRQ-------------SSEAEIQAKARQAEAAE 1444
Query: 417 AELVRLREAVRSLQ---EQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELL 473
+R+ E +R ++ E R+ E ++R EA +A++ AE+LR ++
Sbjct: 1445 RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1504
Query: 474 QERLRGQEQALRFEQERRTWQE---EKERVLRYQREIQGGYMDMYRRNQALEQE 524
E R ++ + + E EK+R L+ E++ + RR + E E
Sbjct: 1505 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE 1558
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/282 (23%), Positives = 126/282 (44%), Gaps = 30/282 (10%)
Query: 255 AEEMGAVLPETCEELKRGLGDEDGSNPFTQVLE---ERQRLWLAELKRLYVERLHEVTQK 311
A+E L E E++ + L +E + F + LE +RQ AE +RL + R+ E+++
Sbjct: 2339 AQEQARRLQEDKEQMAQQLAEE--TQGFQRTLEAERQRQLEMSAEAERLKL-RVAEMSRA 2395
Query: 312 AERSERNLQLQLFMAQQEQRRL-RKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV 370
R+E + Q A++ +L R EL Q+ + ++D A EA
Sbjct: 2396 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA---- 2451
Query: 371 CQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQ--LRGSRAQAQAQDAELVRLREAVRS 428
AE+ K++L++ L K E+ +++ + L+ ++A Q+ +E L + R
Sbjct: 2452 ---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2508
Query: 429 LQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQ 488
++++ + E E A + R+ ++ + ++ QER Q E+
Sbjct: 2509 IEQEKAKLEQLFQDEV-----------AKAQQLREEQQRQQQQMEQER---QRLVASMEE 2554
Query: 489 ERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
RR E +E V R Q E+Q ++ + L +E + LRE
Sbjct: 2555 ARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2596
Score = 41.6 bits (96), Expect = 0.002
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 20/230 (8%)
Query: 288 ERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRK---------ELR 338
ER +L E RL ++ EV Q+ ++ + Q A++E RR K EL
Sbjct: 1632 ERWQLKANEALRLRLQA-EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1690
Query: 339 AQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEI 398
Q+ A GT + + + R E Q + LL+++L Q E A +
Sbjct: 1691 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1750
Query: 399 FSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQA-PREEAPG----SCETDDCKSRGLL 453
L+ +L RA+ + A R E RS E++ R EA + + R L
Sbjct: 1751 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1810
Query: 454 GEAGGSE--ARDSAEQLRAE---LLQERLRGQEQALRFEQERRTWQEEKE 498
EA A + A + RAE +L E+L +A R + E +EKE
Sbjct: 1811 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKE 1860
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/285 (23%), Positives = 113/285 (39%), Gaps = 52/285 (18%)
Query: 298 KRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQ--QGLAPEPRAPGTLPE 355
KR E L ++ Q +E + Q A++ + R+ +E+R Q A E + G E
Sbjct: 1415 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1474
Query: 356 ADPSARPEEEARWEVCQKTAEISLLKQQL-------REAQAELAQKL---AEIFSLKTQ- 404
EEA + Q E L++Q+ R+A+ ELA ++ AE K +
Sbjct: 1475 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1534
Query: 405 --------LRGSRAQAQAQDAELVRLREAVRSLQ------------------------EQ 432
L+ A+ + + AE+ R R+ +L+ E+
Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1594
Query: 433 APREEAPGSCETDDCKSRGLLGEAGGSEARDSAE------QLRA-ELLQERLRGQEQALR 485
+ +EE + + R +A AR+ AE QL+A E L+ RL+ +E A +
Sbjct: 1595 SLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ 1654
Query: 486 FEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
+ +++KE R R R+ + EQEL R+
Sbjct: 1655 KSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699
Score = 38.9 bits (89), Expect = 0.012
Identities = 64/281 (22%), Positives = 114/281 (40%), Gaps = 46/281 (16%)
Query: 295 AELKRLYVERLHEVTQKAE-----RSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRA 349
A R VE + Q AE R++ + + EQ R+ Q L + A
Sbjct: 2104 AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA 2163
Query: 350 PGTLPE----ADPSARPEEEARWEVC-----------QKTA---EISLLKQQLREAQAEL 391
+ + A+ + R + + E+ QK E+ LK + EA +
Sbjct: 2164 DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQR 2223
Query: 392 AQKLAEIFSLKTQ---LRGSRAQAQAQDAELVRLRE---AVRSLQEQAPR------EEAP 439
+Q E+FS++ Q L +A+ +A++ L+ LR+ R LQE+A + E A
Sbjct: 2224 SQVEEELFSVRVQMEELSKLKARIEAENRALI-LRDKDNTQRFLQEEAEKMKQVAEEAAR 2282
Query: 440 GSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQE-----RLRGQEQALRFEQE----- 489
S + L E ++ R AE++ E +Q RL+ + + L+ ++E
Sbjct: 2283 LSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2342
Query: 490 RRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
R QE+KE++ + E G+ + + E+ A E
Sbjct: 2343 ARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2383
Score = 37.4 bits (85), Expect = 0.035
Identities = 42/142 (29%), Positives = 60/142 (42%), Gaps = 23/142 (16%)
Query: 381 KQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPG 440
++QL+EAQA A L E+ + K L+ RAQA+AQ LR+ +R QE R
Sbjct: 1109 EEQLKEAQAVPAT-LPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGER----- 1162
Query: 441 SCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERV 500
L + G RD + E + + L + L R+ E+ R
Sbjct: 1163 ------------LQQRHGE--RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1208
Query: 501 LRYQREIQ---GGYMDMYRRNQ 519
LRY RE G ++ RR Q
Sbjct: 1209 LRYYRESADPLGAWLQDARRRQ 1230
Score = 37.4 bits (85), Expect = 0.035
Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 61/241 (25%)
Query: 294 LAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQE-QRRLRKELRAQQGLAPEPRAPGT 352
L E++RL ++ E + ER+E+ QL +AQ+ Q+RL+ E +A
Sbjct: 2008 LEEVERLKA-KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH------------ 2054
Query: 353 LPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAE-IFSLKTQLRGSRAQ 411
A ++ E+ Q + + QLR +AE A++ AE + Q AQ
Sbjct: 2055 -------AFAVQQKEQELQQTLQQEQSVLDQLR-GEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 412 AQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAE 471
++ Q E RL++ S +EQA ++A+ +AE+LR E
Sbjct: 2107 SRRQVEEAERLKQ---SAEEQAQAR----------------------AQAQAAAEKLRKE 2141
Query: 472 LLQE---RLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRAL 528
QE R + ++ ALR +Q E+ ++ R+ +EQEL L
Sbjct: 2142 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAE----------QTLRQKAQVEQELTTL 2191
Query: 529 R 529
R
Sbjct: 2192 R 2192
Score = 36.6 bits (83), Expect = 0.060
Identities = 68/261 (26%), Positives = 117/261 (44%), Gaps = 37/261 (14%)
Query: 283 TQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNL-----QLQLFMAQ----QEQRRL 333
T+ E++++L EL RL E TQK + E L ++++ +A +E+ R
Sbjct: 1722 TEQGEQQRQLLEEELARLQREAA-AATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1780
Query: 334 RKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQ 393
E Q+ A R EA EEA+ + ++ AE +Q+ EA+ LA+
Sbjct: 1781 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ--RQLAEEDAARQRA-EAERVLAE 1837
Query: 394 KLA---EIFSLKTQLRGSRAQAQAQDAELVRLRE----AVRSLQEQAPREEAPGSCETDD 446
KLA E LKT+ + + +A++ L RL E R L+EQA + +A D
Sbjct: 1838 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA-------D 1890
Query: 447 CKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQRE 506
+ R A +A DS + + L+++ LR + Q E+E + E+ + E
Sbjct: 1891 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQV---EEEILALKASFEKAAAGKAE 1943
Query: 507 IQGGYMDMYRRNQALEQELRA 527
++ +++ R E LR+
Sbjct: 1944 LE---LELGRIRSNAEDTLRS 1961
Score = 35.8 bits (81), Expect = 0.10
Identities = 58/236 (24%), Positives = 103/236 (43%), Gaps = 25/236 (10%)
Query: 288 ERQRL--WLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKE----LRAQQ 341
+R+RL A+ K ERL ++ +KA SE Q L QRR +E L+A
Sbjct: 1876 QRRRLEEQAAQHKADIEERLAQL-RKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1934
Query: 342 GLAPEPRAPGTLP------EADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKL 395
A +A L A+ + R +E+A E ++ + +++ REA+ + + L
Sbjct: 1935 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL 1994
Query: 396 AEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGE 455
A Q + + + + A++ E R L+E+A +E A + + L E
Sbjct: 1995 AAEEEAARQRKAALEEVERLKAKV----EEARRLRERAEQESARQLQLAQEAAQKRLQAE 2050
Query: 456 AGGSEARDSAEQLRAELLQERLRGQEQAL-----RFEQERRTWQEEKERVLRYQRE 506
+A A Q + + LQ+ L+ ++ L E RR +E +E ++ +RE
Sbjct: 2051 ---EKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103
Score = 33.9 bits (76), Expect = 0.39
Identities = 58/223 (26%), Positives = 93/223 (41%), Gaps = 38/223 (17%)
Query: 337 LRAQQGLAPEPRA-PGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKL 395
LRA + E +A P TLPE + + ++ R + + L+ +LR AQ E+ ++L
Sbjct: 1105 LRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ-EVGERL 1163
Query: 396 AEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGL--- 452
Q G R D E+ R RE V L E+ A + + G
Sbjct: 1164 -------QQRHGER------DVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1210
Query: 453 --------LGEAGGSEARDSAEQLRA------ELLQERLRGQEQALRFEQERRTWQEEKE 498
LG A +AR EQ++A + ++E+LR QEQAL E ER E+ E
Sbjct: 1211 YYRESADPLG-AWLQDARRRQEQIQAMPLADSQAVREQLR-QEQALLEEIERH--GEKVE 1266
Query: 499 RVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLES 541
R+ ++ D + + +L + P P+++S
Sbjct: 1267 ECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK--KPKVQS 1307
Score = 31.2 bits (69), Expect = 2.5
Identities = 46/226 (20%), Positives = 93/226 (41%), Gaps = 27/226 (11%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWE 369
Q A R + +Q M + + +R++LR +Q L E G + E
Sbjct: 1224 QDARRRQEQIQA---MPLADSQAVREQLRQEQALLEEIERHGE--------------KVE 1266
Query: 370 VCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDA--ELVRLREAVR 427
CQ+ A+ + +++ + +L A++ + + + + Q+ ++ E V LR
Sbjct: 1267 ECQRFAKQYI--NAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYS 1324
Query: 428 SLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFE 487
L + S + L E +E R+ ++ A L ++R + A
Sbjct: 1325 ELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKA 1384
Query: 488 QERRTWQEEKERVLRYQREI---QGGYMDMYRRNQALEQELRALRE 530
Q R E KE R Q E+ + +D ++ +++++EL+ LR+
Sbjct: 1385 QAER---EAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1427
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 50.8 bits (120), Expect = 3e-06
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 21/226 (9%)
Query: 287 EERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQ--QGLA 344
EE +R L++ VER +V E ++R+ + +L Q +R E AQ + L
Sbjct: 1550 EEAER----RLRQAEVERARQVQVALETAQRSAEAEL----QSKRASFAEKTAQLERSLQ 1601
Query: 345 PEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQ 404
E A L E + R +++A E ++ AE L + QL+ +A + AE + +
Sbjct: 1602 EEHVAVAQLRE-EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1660
Query: 405 LRGSRAQAQAQDAELVRLREAVR--SLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAR 462
L + A+ Q ++AE REA R +EQA R+ E + K R L G ++ R
Sbjct: 1661 LAQAEAEKQKEEAE----REARRRGKAEEQAVRQRELAEQELE--KQRQL--AEGTAQQR 1712
Query: 463 DSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQ 508
+AEQ L E +G++Q E+E Q E + ++E++
Sbjct: 1713 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELE 1758
Score = 49.7 bits (117), Expect = 7e-06
Identities = 55/234 (23%), Positives = 96/234 (41%), Gaps = 22/234 (9%)
Query: 297 LKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEA 356
L+R+ E Q+AE ER +++ A E++R E AQ E A
Sbjct: 1345 LRRMEEEERLAEQQRAEERERLAEVE---AALEKQRQLAEAHAQAKAQAEREAKELQQRM 1401
Query: 357 DPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQD 416
EEA + Q+ I QQLR+ S + +++ QA+A +
Sbjct: 1402 QEEVVRREEAAVDAQQQKRSIQEELQQLRQ-------------SSEAEIQAKARQAEAAE 1448
Query: 417 AELVRLREAVRSLQ---EQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELL 473
+R+ E +R ++ E R+ E ++R EA +A++ AE+LR ++
Sbjct: 1449 RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1508
Query: 474 QERLRGQEQALRFEQERRTWQE---EKERVLRYQREIQGGYMDMYRRNQALEQE 524
E R ++ + + E EK+R L+ E++ + RR + E E
Sbjct: 1509 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVE 1562
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/282 (23%), Positives = 126/282 (44%), Gaps = 30/282 (10%)
Query: 255 AEEMGAVLPETCEELKRGLGDEDGSNPFTQVLE---ERQRLWLAELKRLYVERLHEVTQK 311
A+E L E E++ + L +E + F + LE +RQ AE +RL + R+ E+++
Sbjct: 2343 AQEQARRLQEDKEQMAQQLAEE--TQGFQRTLEAERQRQLEMSAEAERLKL-RVAEMSRA 2399
Query: 312 AERSERNLQLQLFMAQQEQRRL-RKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEV 370
R+E + Q A++ +L R EL Q+ + ++D A EA
Sbjct: 2400 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA---- 2455
Query: 371 CQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQ--LRGSRAQAQAQDAELVRLREAVRS 428
AE+ K++L++ L K E+ +++ + L+ ++A Q+ +E L + R
Sbjct: 2456 ---IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2512
Query: 429 LQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQ 488
++++ + E E A + R+ ++ + ++ QER Q E+
Sbjct: 2513 IEQEKAKLEQLFQDEV-----------AKAQQLREEQQRQQQQMEQER---QRLVASMEE 2558
Query: 489 ERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
RR E +E V R Q E+Q ++ + L +E + LRE
Sbjct: 2559 ARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2600
Score = 41.6 bits (96), Expect = 0.002
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 20/230 (8%)
Query: 288 ERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRK---------ELR 338
ER +L E RL ++ EV Q+ ++ + Q A++E RR K EL
Sbjct: 1636 ERWQLKANEALRLRLQA-EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1694
Query: 339 AQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEI 398
Q+ A GT + + + R E Q + LL+++L Q E A +
Sbjct: 1695 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1754
Query: 399 FSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQA-PREEAPG----SCETDDCKSRGLL 453
L+ +L RA+ + A R E RS E++ R EA + + R L
Sbjct: 1755 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1814
Query: 454 GEAGGSE--ARDSAEQLRAE---LLQERLRGQEQALRFEQERRTWQEEKE 498
EA A + A + RAE +L E+L +A R + E +EKE
Sbjct: 1815 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKE 1864
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/285 (23%), Positives = 113/285 (39%), Gaps = 52/285 (18%)
Query: 298 KRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQ--QGLAPEPRAPGTLPE 355
KR E L ++ Q +E + Q A++ + R+ +E+R Q A E + G E
Sbjct: 1419 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1478
Query: 356 ADPSARPEEEARWEVCQKTAEISLLKQQL-------REAQAELAQKL---AEIFSLKTQ- 404
EEA + Q E L++Q+ R+A+ ELA ++ AE K +
Sbjct: 1479 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1538
Query: 405 --------LRGSRAQAQAQDAELVRLREAVRSLQ------------------------EQ 432
L+ A+ + + AE+ R R+ +L+ E+
Sbjct: 1539 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1598
Query: 433 APREEAPGSCETDDCKSRGLLGEAGGSEARDSAE------QLRA-ELLQERLRGQEQALR 485
+ +EE + + R +A AR+ AE QL+A E L+ RL+ +E A +
Sbjct: 1599 SLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ 1658
Query: 486 FEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
+ +++KE R R R+ + EQEL R+
Sbjct: 1659 KSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1703
Score = 38.9 bits (89), Expect = 0.012
Identities = 64/281 (22%), Positives = 114/281 (40%), Gaps = 46/281 (16%)
Query: 295 AELKRLYVERLHEVTQKAE-----RSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRA 349
A R VE + Q AE R++ + + EQ R+ Q L + A
Sbjct: 2108 AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA 2167
Query: 350 PGTLPE----ADPSARPEEEARWEVC-----------QKTA---EISLLKQQLREAQAEL 391
+ + A+ + R + + E+ QK E+ LK + EA +
Sbjct: 2168 DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQR 2227
Query: 392 AQKLAEIFSLKTQ---LRGSRAQAQAQDAELVRLRE---AVRSLQEQAPR------EEAP 439
+Q E+FS++ Q L +A+ +A++ L+ LR+ R LQE+A + E A
Sbjct: 2228 SQVEEELFSVRVQMEELSKLKARIEAENRALI-LRDKDNTQRFLQEEAEKMKQVAEEAAR 2286
Query: 440 GSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQE-----RLRGQEQALRFEQE----- 489
S + L E ++ R AE++ E +Q RL+ + + L+ ++E
Sbjct: 2287 LSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2346
Query: 490 RRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALRE 530
R QE+KE++ + E G+ + + E+ A E
Sbjct: 2347 ARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2387
Score = 37.4 bits (85), Expect = 0.035
Identities = 42/142 (29%), Positives = 60/142 (42%), Gaps = 23/142 (16%)
Query: 381 KQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPG 440
++QL+EAQA A L E+ + K L+ RAQA+AQ LR+ +R QE R
Sbjct: 1113 EEQLKEAQAVPAT-LPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGER----- 1166
Query: 441 SCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERV 500
L + G RD + E + + L + L R+ E+ R
Sbjct: 1167 ------------LQQRHGE--RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1212
Query: 501 LRYQREIQ---GGYMDMYRRNQ 519
LRY RE G ++ RR Q
Sbjct: 1213 LRYYRESADPLGAWLQDARRRQ 1234
Score = 37.4 bits (85), Expect = 0.035
Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 61/241 (25%)
Query: 294 LAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQE-QRRLRKELRAQQGLAPEPRAPGT 352
L E++RL ++ E + ER+E+ QL +AQ+ Q+RL+ E +A
Sbjct: 2012 LEEVERLKA-KVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH------------ 2058
Query: 353 LPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAE-IFSLKTQLRGSRAQ 411
A ++ E+ Q + + QLR +AE A++ AE + Q AQ
Sbjct: 2059 -------AFAVQQKEQELQQTLQQEQSVLDQLR-GEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 412 AQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAE 471
++ Q E RL++ S +EQA ++A+ +AE+LR E
Sbjct: 2111 SRRQVEEAERLKQ---SAEEQAQAR----------------------AQAQAAAEKLRKE 2145
Query: 472 LLQE---RLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRAL 528
QE R + ++ ALR +Q E+ ++ R+ +EQEL L
Sbjct: 2146 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAE----------QTLRQKAQVEQELTTL 2195
Query: 529 R 529
R
Sbjct: 2196 R 2196
Score = 36.6 bits (83), Expect = 0.060
Identities = 68/261 (26%), Positives = 117/261 (44%), Gaps = 37/261 (14%)
Query: 283 TQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNL-----QLQLFMAQ----QEQRRL 333
T+ E++++L EL RL E TQK + E L ++++ +A +E+ R
Sbjct: 1726 TEQGEQQRQLLEEELARLQREAA-AATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1784
Query: 334 RKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQ 393
E Q+ A R EA EEA+ + ++ AE +Q+ EA+ LA+
Sbjct: 1785 TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ--RQLAEEDAARQRA-EAERVLAE 1841
Query: 394 KLA---EIFSLKTQLRGSRAQAQAQDAELVRLRE----AVRSLQEQAPREEAPGSCETDD 446
KLA E LKT+ + + +A++ L RL E R L+EQA + +A D
Sbjct: 1842 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA-------D 1894
Query: 447 CKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQRE 506
+ R A +A DS + + L+++ LR + Q E+E + E+ + E
Sbjct: 1895 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQV---EEEILALKASFEKAAAGKAE 1947
Query: 507 IQGGYMDMYRRNQALEQELRA 527
++ +++ R E LR+
Sbjct: 1948 LE---LELGRIRSNAEDTLRS 1965
Score = 35.8 bits (81), Expect = 0.10
Identities = 58/236 (24%), Positives = 103/236 (43%), Gaps = 25/236 (10%)
Query: 288 ERQRL--WLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKE----LRAQQ 341
+R+RL A+ K ERL ++ +KA SE Q L QRR +E L+A
Sbjct: 1880 QRRRLEEQAAQHKADIEERLAQL-RKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1938
Query: 342 GLAPEPRAPGTLP------EADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKL 395
A +A L A+ + R +E+A E ++ + +++ REA+ + + L
Sbjct: 1939 EKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL 1998
Query: 396 AEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGE 455
A Q + + + + A++ E R L+E+A +E A + + L E
Sbjct: 1999 AAEEEAARQRKAALEEVERLKAKV----EEARRLRERAEQESARQLQLAQEAAQKRLQAE 2054
Query: 456 AGGSEARDSAEQLRAELLQERLRGQEQAL-----RFEQERRTWQEEKERVLRYQRE 506
+A A Q + + LQ+ L+ ++ L E RR +E +E ++ +RE
Sbjct: 2055 ---EKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2107
Score = 33.9 bits (76), Expect = 0.39
Identities = 58/223 (26%), Positives = 93/223 (41%), Gaps = 38/223 (17%)
Query: 337 LRAQQGLAPEPRA-PGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKL 395
LRA + E +A P TLPE + + ++ R + + L+ +LR AQ E+ ++L
Sbjct: 1109 LRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ-EVGERL 1167
Query: 396 AEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGL--- 452
Q G R D E+ R RE V L E+ A + + G
Sbjct: 1168 -------QQRHGER------DVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1214
Query: 453 --------LGEAGGSEARDSAEQLRA------ELLQERLRGQEQALRFEQERRTWQEEKE 498
LG A +AR EQ++A + ++E+LR QEQAL E ER E+ E
Sbjct: 1215 YYRESADPLG-AWLQDARRRQEQIQAMPLADSQAVREQLR-QEQALLEEIERH--GEKVE 1270
Query: 499 RVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLES 541
R+ ++ D + + +L + P P+++S
Sbjct: 1271 ECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK--KPKVQS 1311
Score = 31.2 bits (69), Expect = 2.5
Identities = 46/226 (20%), Positives = 93/226 (41%), Gaps = 27/226 (11%)
Query: 310 QKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWE 369
Q A R + +Q M + + +R++LR +Q L E G + E
Sbjct: 1228 QDARRRQEQIQA---MPLADSQAVREQLRQEQALLEEIERHGE--------------KVE 1270
Query: 370 VCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDA--ELVRLREAVR 427
CQ+ A+ + +++ + +L A++ + + + + Q+ ++ E V LR
Sbjct: 1271 ECQRFAKQYI--NAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYS 1328
Query: 428 SLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFE 487
L + S + L E +E R+ ++ A L ++R + A
Sbjct: 1329 ELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKA 1388
Query: 488 QERRTWQEEKERVLRYQREI---QGGYMDMYRRNQALEQELRALRE 530
Q R E KE R Q E+ + +D ++ +++++EL+ LR+
Sbjct: 1389 QAER---EAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1431
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,773,777
Number of Sequences: 37866
Number of extensions: 1454831
Number of successful extensions: 10739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 775
Number of HSP's that attempted gapping in prelim test: 7403
Number of HSP's gapped (non-prelim): 2769
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.