Guide to the Human Genome
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Search of human proteins with 62122911

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62122911 interleukin 31 [Homo sapiens]
         (164 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62122911 interleukin 31 [Homo sapiens]                             328   1e-90
gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]         32   0.19 
gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]          32   0.19 
gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]         32   0.19 
gi|229577391 pyridine nucleotide-disulphide oxidoreductase domai...    30   0.94 
gi|209364523 alsin isoform 2 [Homo sapiens]                            29   1.6  
gi|40316935 alsin isoform 1 [Homo sapiens]                             29   1.6  
gi|5901948 FAS-associated factor 1 [Homo sapiens]                      29   2.1  
gi|57863255 zinc finger, SWIM domain containing 3 [Homo sapiens]       28   2.7  
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]      28   3.6  
gi|239753760 PREDICTED: hypothetical protein, partial [Homo sapi...    28   4.6  
gi|239742226 PREDICTED: hypothetical protein [Homo sapiens]            28   4.6  
gi|22749191 tetratricopeptide repeat domain 39B [Homo sapiens]         28   4.6  
gi|38348264 olfactomedin-like 1 [Homo sapiens]                         28   4.6  
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom...    27   6.1  
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad...    27   6.1  
gi|28329436 aprataxin isoform a [Homo sapiens]                         27   6.1  
gi|28329433 aprataxin isoform c [Homo sapiens]                         27   6.1  
gi|28329427 aprataxin isoform d [Homo sapiens]                         27   6.1  
gi|8923156 aprataxin isoform d [Homo sapiens]                          27   6.1  
gi|55741653 hypothetical protein LOC57691 [Homo sapiens]               27   6.1  
gi|36949366 mutS homolog 4 [Homo sapiens]                              27   7.9  
gi|215599324 coiled-coil domain containing 114 isoform 2 [Homo s...    27   7.9  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            27   7.9  

>gi|62122911 interleukin 31 [Homo sapiens]
          Length = 164

 Score =  328 bits (842), Expect = 1e-90
 Identities = 164/164 (100%), Positives = 164/164 (100%)

Query: 1   MASHSGPSTSVLFLFCCLGGWLASHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEK 60
           MASHSGPSTSVLFLFCCLGGWLASHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEK
Sbjct: 1   MASHSGPSTSVLFLFCCLGGWLASHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEK 60

Query: 61  GVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAP 120
           GVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAP
Sbjct: 61  GVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAP 120

Query: 121 ETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT 164
           ETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT
Sbjct: 121 ETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT 164


>gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]
          Length = 734

 Score = 32.3 bits (72), Expect = 0.19
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 9/118 (7%)

Query: 36  DDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTI 95
           +D+QK +EE + L     +  E+ K V       L  L  +A     +     R Y++TI
Sbjct: 64  EDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETI 123

Query: 96  RQLDN-KSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLAL 152
            +L N K+ ++   + L+K    +A E  +     T EC+  + T+ +  S  ++ +L
Sbjct: 124 EKLQNDKAKLEVKSQTLEK----EAKECRLR----TEECQLQLKTLHEDLSGRLEESL 173


>gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]
          Length = 769

 Score = 32.3 bits (72), Expect = 0.19
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 9/118 (7%)

Query: 36  DDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTI 95
           +D+QK +EE + L     +  E+ K V       L  L  +A     +     R Y++TI
Sbjct: 110 EDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETI 169

Query: 96  RQLDN-KSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLAL 152
            +L N K+ ++   + L+K    +A E  +     T EC+  + T+ +  S  ++ +L
Sbjct: 170 EKLQNDKAKLEVKSQTLEK----EAKECRLR----TEECQLQLKTLHEDLSGRLEESL 219


>gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]
          Length = 780

 Score = 32.3 bits (72), Expect = 0.19
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 9/118 (7%)

Query: 36  DDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTI 95
           +D+QK +EE + L     +  E+ K V       L  L  +A     +     R Y++TI
Sbjct: 110 EDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETI 169

Query: 96  RQLDN-KSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLAL 152
            +L N K+ ++   + L+K    +A E  +     T EC+  + T+ +  S  ++ +L
Sbjct: 170 EKLQNDKAKLEVKSQTLEK----EAKECRLR----TEECQLQLKTLHEDLSGRLEESL 219


>gi|229577391 pyridine nucleotide-disulphide oxidoreductase domain 2
           [Homo sapiens]
          Length = 581

 Score = 30.0 bits (66), Expect = 0.94
 Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 7/118 (5%)

Query: 39  QKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAI-RAYLKTIRQ 97
           +K V ++Q  S+  ++ V  E G  V     L   SP            +   +L+ I Q
Sbjct: 308 EKTVAKVQVNSEGCVQGVVLEDGTEVRSKMVLSNTSPQITFLKLTPQEWLPEEFLERISQ 367

Query: 98  LDNKSVIDEIIEHLDKL-IFQDAPETNISVPTDTHECKRFI-----LTISQQFSECMD 149
           LD +S + +I   +D+L  F  AP      P   H+C   +     L + Q F + MD
Sbjct: 368 LDTRSPVTKINVAVDRLPSFLAAPNAPRGQPLPHHQCSIHLNCEDTLLLHQAFEDAMD 425


>gi|209364523 alsin isoform 2 [Homo sapiens]
          Length = 396

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 13/49 (26%), Positives = 27/49 (55%)

Query: 23  ASHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLP 71
           A H+L +    PS D++ + E     S++L+   ++E  V++S ++  P
Sbjct: 210 AFHSLALVQCLPSQDLKPVPERCNQCSQLLITMTDKEDHVIISDSHCCP 258


>gi|40316935 alsin isoform 1 [Homo sapiens]
          Length = 1657

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 13/49 (26%), Positives = 27/49 (55%)

Query: 23  ASHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLP 71
           A H+L +    PS D++ + E     S++L+   ++E  V++S ++  P
Sbjct: 210 AFHSLALVQCLPSQDLKPVPERCNQCSQLLITMTDKEDHVIISDSHCCP 258


>gi|5901948 FAS-associated factor 1 [Homo sapiens]
          Length = 650

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 25/67 (37%), Positives = 42/67 (62%), Gaps = 11/67 (16%)

Query: 37  DVQKIVE-ELQ-SLSKMLLK-----DVEEE---KGVLVSQNYTLPCLSPDAQPP-NNIHS 85
           ++++I+E ELQ  +SKMLLK     DVE+    K + + +N +L  L+PD  PP ++ H+
Sbjct: 124 EIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHA 183

Query: 86  PAIRAYL 92
            A++  L
Sbjct: 184 GALQESL 190


>gi|57863255 zinc finger, SWIM domain containing 3 [Homo sapiens]
          Length = 696

 Score = 28.5 bits (62), Expect = 2.7
 Identities = 20/92 (21%), Positives = 44/92 (47%), Gaps = 7/92 (7%)

Query: 42  VEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPA----IRAYLKTIRQ 97
           ++ LQ +     KD++  +  LV  ++ L  +   ++P     +P+    I   +K   +
Sbjct: 124 LQRLQPVQPTTKKDLDTAEKSLVEPSFCLDKVQVSSKPEQEGITPSDLAKIAKVMKNFLK 183

Query: 98  LDNKSVIDEII---EHLDKLIFQDAPETNISV 126
           +D  S+    +   +HLD+L FQ +  T++ +
Sbjct: 184 VDEGSMASFSVGDSQHLDRLSFQSSKMTDLFI 215


>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
          Length = 757

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 23/92 (25%), Positives = 46/92 (50%), Gaps = 12/92 (13%)

Query: 26  TLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHS 85
           T   R L+ S  + + V +L+  + ++LKD+E  K  +         LS +    N++ +
Sbjct: 568 TTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQ-------LSQELDRANSLLN 620

Query: 86  PAIRAY---LKTIRQLDNKSVIDEIIEHLDKL 114
              + Y   ++++RQ D+K  ID + E + +L
Sbjct: 621 QTQQPYRYLIESVRQRDSK--IDSLTESIAQL 650


>gi|239753760 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 267

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 13/30 (43%), Positives = 20/30 (66%), Gaps = 1/30 (3%)

Query: 63  LVSQNYTLPCLSPDAQPPN-NIHSPAIRAY 91
           +++  + LP  SPDA+P N NI SP + +Y
Sbjct: 133 VLNLQHWLPTRSPDARPSNCNISSPRVSSY 162


>gi|239742226 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 303

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 13/30 (43%), Positives = 20/30 (66%), Gaps = 1/30 (3%)

Query: 63  LVSQNYTLPCLSPDAQPPN-NIHSPAIRAY 91
           +++  + LP  SPDA+P N NI SP + +Y
Sbjct: 133 VLNLQHWLPTRSPDARPSNCNISSPRVSSY 162


>gi|22749191 tetratricopeptide repeat domain 39B [Homo sapiens]
          Length = 616

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 6/52 (11%)

Query: 23  ASHTLPVRLLRPSDDVQ------KIVEELQSLSKMLLKDVEEEKGVLVSQNY 68
           AS   PV+L+ P+ ++        IV + + LS+ LL  VE+ +  L SQN+
Sbjct: 459 ASLPAPVKLILPALEMMYVWNGFSIVSKRKDLSENLLVTVEKAEAALQSQNF 510


>gi|38348264 olfactomedin-like 1 [Homo sapiens]
          Length = 402

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 14/34 (41%), Positives = 25/34 (73%), Gaps = 2/34 (5%)

Query: 29  VRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGV 62
           ++ LR +D+   IV E ++L++MLL++ EEEK +
Sbjct: 102 IQYLREADEC--IVSEDKTLAEMLLQEAEEEKKI 133


>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
           sapiens]
          Length = 2644

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 89  RAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECM 148
           R+ L+++++LD ++ ID++++  D LI+    + N S      E    +L++   +S   
Sbjct: 548 RSLLESVQKLDLEATIDKVVKIYDALIYM---QVNSSFEDHILEDLCGMLSLPWIYSHSD 604

Query: 149 DLALKSLTSGAQQAT 163
           D  LK  T  A   T
Sbjct: 605 DGCLKLTTFAANLLT 619


>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
           related protein, partial [Homo sapiens]
          Length = 2105

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 89  RAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECM 148
           R+ L+++++LD ++ ID++++  D LI+    + N S      E    +L++   +S   
Sbjct: 306 RSLLESVQKLDLEATIDKVVKIYDALIYM---QVNSSFEDHILEDLCGMLSLPWIYSHSD 362

Query: 149 DLALKSLTSGAQQAT 163
           D  LK  T  A   T
Sbjct: 363 DGCLKLTTFAANLLT 377


>gi|28329436 aprataxin isoform a [Homo sapiens]
          Length = 342

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 19/80 (23%), Positives = 40/80 (50%), Gaps = 11/80 (13%)

Query: 63  LVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPET 122
           ++SQ++  PCL       N  H  +      T   L++++VI E+++   ++  +D    
Sbjct: 263 VISQDFDSPCLK------NKKHWNSFN----TEYFLESQAVI-EMVQEAGRVTVRDGMPE 311

Query: 123 NISVPTDTHECKRFILTISQ 142
            + +P   HEC++ + +I Q
Sbjct: 312 LLKLPLRCHECQQLLPSIPQ 331


>gi|28329433 aprataxin isoform c [Homo sapiens]
          Length = 254

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 19/80 (23%), Positives = 40/80 (50%), Gaps = 11/80 (13%)

Query: 63  LVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPET 122
           ++SQ++  PCL       N  H  +      T   L++++VI E+++   ++  +D    
Sbjct: 175 VISQDFDSPCLK------NKKHWNSFN----TEYFLESQAVI-EMVQEAGRVTVRDGMPE 223

Query: 123 NISVPTDTHECKRFILTISQ 142
            + +P   HEC++ + +I Q
Sbjct: 224 LLKLPLRCHECQQLLPSIPQ 243


>gi|28329427 aprataxin isoform d [Homo sapiens]
          Length = 168

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 19/80 (23%), Positives = 40/80 (50%), Gaps = 11/80 (13%)

Query: 63  LVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPET 122
           ++SQ++  PCL       N  H  +      T   L++++VI E+++   ++  +D    
Sbjct: 89  VISQDFDSPCLK------NKKHWNSFN----TEYFLESQAVI-EMVQEAGRVTVRDGMPE 137

Query: 123 NISVPTDTHECKRFILTISQ 142
            + +P   HEC++ + +I Q
Sbjct: 138 LLKLPLRCHECQQLLPSIPQ 157


>gi|8923156 aprataxin isoform d [Homo sapiens]
          Length = 168

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 19/80 (23%), Positives = 40/80 (50%), Gaps = 11/80 (13%)

Query: 63  LVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPET 122
           ++SQ++  PCL       N  H  +      T   L++++VI E+++   ++  +D    
Sbjct: 89  VISQDFDSPCLK------NKKHWNSFN----TEYFLESQAVI-EMVQEAGRVTVRDGMPE 137

Query: 123 NISVPTDTHECKRFILTISQ 142
            + +P   HEC++ + +I Q
Sbjct: 138 LLKLPLRCHECQQLLPSIPQ 157


>gi|55741653 hypothetical protein LOC57691 [Homo sapiens]
          Length = 787

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 1/74 (1%)

Query: 73  LSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHE 132
           L P   P   I SP I A  KT+  L      +  +    + +  +    N+S+PT  ++
Sbjct: 634 LEPSTWPYEEITSPWI-AGEKTLFHLCKILKYEVDLNDFREFVNNNIKSNNVSIPTTIYK 692

Query: 133 CKRFILTISQQFSE 146
            K+ + TI+   +E
Sbjct: 693 AKKIVSTIAINSAE 706


>gi|36949366 mutS homolog 4 [Homo sapiens]
          Length = 936

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 9/121 (7%)

Query: 37  DVQKIVEELQSLSKMLLKDVEEEKGV-LVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTI 95
           D ++++  L  + K    +  E K   L+   +TL  + P      N ++P +RAY  ++
Sbjct: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSL 453

Query: 96  RQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSL 155
              D +  I  I+E +  +I  DA      +   T +C      +    +E +D+A ++ 
Sbjct: 454 E--DKRFGI--ILEKIKTVINDDARYMKGCLNMRTQKC----YAVRSNINEFLDIARRTY 505

Query: 156 T 156
           T
Sbjct: 506 T 506


>gi|215599324 coiled-coil domain containing 114 isoform 2 [Homo
           sapiens]
          Length = 670

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 10/90 (11%)

Query: 30  RLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIR 89
           RLL+    VQ  +EELQ  ++ L K ++E +  + +        S + + P  I    ++
Sbjct: 58  RLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTH-------SKNVRSPGFILDQKVK 110

Query: 90  AYLKTIRQLDNKSVIDEIIEHLDKLIFQDA 119
              + IR L+N+  +D +  H D  + ++A
Sbjct: 111 -IRRRIRILENQ--LDRVTCHFDNQLVRNA 137


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 30   RLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIR 89
            +LLR S+DV K+ E+L+S+  +L    E  K  +++        +   +  N++ +  I+
Sbjct: 2838 KLLRTSEDVAKMQEDLESMHPLL---EEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIK 2894

Query: 90   AYLKTIRQL----DNKSVIDEIIEHLD 112
            A  K  +      D +  +DE +  LD
Sbjct: 2895 ANEKAKKAQAIADDAQKDLDEALPALD 2921


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,420,398
Number of Sequences: 37866
Number of extensions: 258406
Number of successful extensions: 939
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 931
Number of HSP's gapped (non-prelim): 27
length of query: 164
length of database: 18,247,518
effective HSP length: 94
effective length of query: 70
effective length of database: 14,688,114
effective search space: 1028167980
effective search space used: 1028167980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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