Search of human proteins with 61888836

Search of human proteins with 61888836

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related)
[Homo sapiens]
         (262 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Hom...   543   e-155
gi|124028517 hematopoietic transcription factor PU.1 isoform 2 [...   174   5e-44
gi|124028521 hematopoietic transcription factor PU.1 isoform 1 [...   174   7e-44
gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Hom...   117   8e-27
gi|34452721 GA binding protein transcription factor, alpha subun...    68   9e-12
gi|209954808 ets-related isoform 4 [Homo sapiens]                      59   4e-09
gi|4758300 ets-related isoform 2 [Homo sapiens]                        59   4e-09
gi|33667107 ets-related isoform 1 [Homo sapiens]                       59   4e-09
gi|209954797 ets-related isoform 3 [Homo sapiens]                      59   4e-09
gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]                    58   1e-08
gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]                     58   1e-08
gi|253683437 ets variant gene 1 isoform f [Homo sapiens]               57   1e-08
gi|253683435 ets variant gene 1 isoform e [Homo sapiens]               57   1e-08
gi|253683433 ets variant gene 1 isoform d [Homo sapiens]               57   1e-08
gi|253683431 ets variant gene 1 isoform c [Homo sapiens]               57   1e-08
gi|253683429 ets variant gene 1 isoform c [Homo sapiens]               57   1e-08
gi|31742534 ets variant gene 1 isoform a [Homo sapiens]                57   1e-08
gi|253683427 ets variant gene 1 isoform b [Homo sapiens]               55   5e-08
gi|219689118 v-ets erythroblastosis virus E26 oncogene homolog 1...    54   1e-07
gi|4885219 v-ets erythroblastosis virus E26 oncogene homolog 1 i...    54   1e-07
gi|241666446 v-ets erythroblastosis virus E26 oncogene homolog 1...    54   1e-07
gi|4885221 v-ets erythroblastosis virus E26 oncogene homolog 2 [...    53   2e-07
gi|8923789 FEV (ETS oncogene family) [Homo sapiens]                    53   3e-07
gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]          52   4e-07
gi|223718207 ets variant gene 3 isoform 1 [Homo sapiens]               52   5e-07
gi|20270188 ets variant gene 3 isoform 2 [Homo sapiens]                52   5e-07
gi|166851840 E74-like factor 3 (ets domain transcription factor,...    52   5e-07
gi|167235023 E74-like factor 3 (ets domain transcription factor,...    52   5e-07
gi|187608767 E74-like factor 4 [Homo sapiens]                          52   7e-07
gi|4503555 E74-like factor 4 [Homo sapiens]                            52   7e-07

>gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Homo
           sapiens]
          Length = 262

 Score =  543 bits (1399), Expect = e-155
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA 60
           MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA
Sbjct: 1   MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA 60

Query: 61  FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY 120
           FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
Sbjct: 61  FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY 120

Query: 121 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT 180
           APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
Sbjct: 121 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT 180

Query: 181 RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI 240
           RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
Sbjct: 181 RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI 240

Query: 241 RKVKRKLTYQFDSALLPAVRRA 262
           RKVKRKLTYQFDSALLPAVRRA
Sbjct: 241 RKVKRKLTYQFDSALLPAVRRA 262


>gi|124028517 hematopoietic transcription factor PU.1 isoform 2
           [Homo sapiens]
          Length = 270

 Score =  174 bits (442), Expect = 5e-44
 Identities = 117/267 (43%), Positives = 150/267 (56%), Gaps = 25/267 (9%)

Query: 4   LEAAQLDGPHFSCLYP---DGVFYDLDSCK---HSSYP----DSEGAPDSLWDWTVAPPV 53
           L+A +++G  F  + P   D V YD D  +   H  YP    D E   D  WD+   P  
Sbjct: 2   LQACKMEG--FPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFH--PHH 57

Query: 54  PATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQ 113
             + +E+F  A   F+  Q+ Q    P       ++EL        P +P +P+      
Sbjct: 58  VHSEFESF--AENNFTELQSVQ---PPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVS 112

Query: 114 TLVPPAYAPYPS----PVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKL 169
            L P     YPS       S+EE+    SP LEVSD E+D  L  GP     E G++KK+
Sbjct: 113 YL-PRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGSKKKI 170

Query: 170 RLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLAR 229
           RLYQFLL LL  GDM++ +WWV+   G FQFSSKHKE LA RWG QKGNRK+MTYQK+AR
Sbjct: 171 RLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMAR 230

Query: 230 ALRNYAKTGEIRKVKRKLTYQFDSALL 256
           ALRNY KTGE++KVK+KLTYQF   +L
Sbjct: 231 ALRNYGKTGEVKKVKKKLTYQFSGEVL 257


>gi|124028521 hematopoietic transcription factor PU.1 isoform 1
           [Homo sapiens]
          Length = 271

 Score =  174 bits (441), Expect = 7e-44
 Identities = 117/268 (43%), Positives = 150/268 (55%), Gaps = 26/268 (9%)

Query: 4   LEAAQLDGPHFSCLYP----DGVFYDLDSCK---HSSYP----DSEGAPDSLWDWTVAPP 52
           L+A +++G  F  + P    D V YD D  +   H  YP    D E   D  WD+   P 
Sbjct: 2   LQACKMEG--FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFH--PH 57

Query: 53  VPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFAS 112
              + +E+F  A   F+  Q+ Q    P       ++EL        P +P +P+     
Sbjct: 58  HVHSEFESF--AENNFTELQSVQ---PPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQV 112

Query: 113 QTLVPPAYAPYPS----PVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKK 168
             L P     YPS       S+EE+    SP LEVSD E+D  L  GP     E G++KK
Sbjct: 113 SYL-PRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGSKKK 170

Query: 169 LRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLA 228
           +RLYQFLL LL  GDM++ +WWV+   G FQFSSKHKE LA RWG QKGNRK+MTYQK+A
Sbjct: 171 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 230

Query: 229 RALRNYAKTGEIRKVKRKLTYQFDSALL 256
           RALRNY KTGE++KVK+KLTYQF   +L
Sbjct: 231 RALRNYGKTGEVKKVKKKLTYQFSGEVL 258


>gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Homo
           sapiens]
          Length = 248

 Score =  117 bits (294), Expect = 8e-27
 Identities = 57/99 (57%), Positives = 73/99 (73%), Gaps = 5/99 (5%)

Query: 158 GKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKG 217
           GKG     RKKLRL+++L   L   +M  C+ WV+   G+FQF SK+KE LA  WG++KG
Sbjct: 105 GKG-----RKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKG 159

Query: 218 NRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALL 256
           NRK MTYQK+ARALRNY ++GEI K++RKLTYQF  A+L
Sbjct: 160 NRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAIL 198


>gi|34452721 GA binding protein transcription factor, alpha subunit
           [Homo sapiens]
          Length = 454

 Score = 67.8 bits (164), Expect = 9e-12
 Identities = 38/93 (40%), Positives = 57/93 (61%), Gaps = 5/93 (5%)

Query: 160 GSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNR 219
           G+  G   +++L+QFLL LLT  D R+C+ WV       +F     EL+A++WGQ+K N+
Sbjct: 311 GNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEG---EFKLNQPELVAQKWGQRK-NK 366

Query: 220 KRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
             M Y+KL+RALR Y     I KV+ ++  Y+F
Sbjct: 367 PTMNYEKLSRALRYYYDGDMICKVQGKRFVYKF 399


>gi|209954808 ets-related isoform 4 [Homo sapiens]
          Length = 387

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 5/131 (3%)

Query: 123 YPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRG 182
           +P+P     +  P   P  E    + D   + GP           +++L+QFLL LL+  
Sbjct: 173 HPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDS 232

Query: 183 DMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRK 242
               C+ W E   G F+ +   +  +ARRWG++K ++  M Y KL+RALR Y     + K
Sbjct: 233 SNSSCITW-EGTNGEFKMTDPDE--VARRWGERK-SKPNMNYDKLSRALRYYYDKNIMTK 288

Query: 243 VK-RKLTYQFD 252
           V  ++  Y+FD
Sbjct: 289 VHGKRYAYKFD 299


>gi|4758300 ets-related isoform 2 [Homo sapiens]
          Length = 462

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 5/131 (3%)

Query: 123 YPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRG 182
           +P+P     +  P   P  E    + D   + GP           +++L+QFLL LL+  
Sbjct: 248 HPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDS 307

Query: 183 DMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRK 242
               C+ W E   G F+ +   +  +ARRWG++K ++  M Y KL+RALR Y     + K
Sbjct: 308 SNSSCITW-EGTNGEFKMTDPDE--VARRWGERK-SKPNMNYDKLSRALRYYYDKNIMTK 363

Query: 243 VK-RKLTYQFD 252
           V  ++  Y+FD
Sbjct: 364 VHGKRYAYKFD 374


>gi|33667107 ets-related isoform 1 [Homo sapiens]
          Length = 479

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 5/131 (3%)

Query: 123 YPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRG 182
           +P+P     +  P   P  E    + D   + GP           +++L+QFLL LL+  
Sbjct: 265 HPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDS 324

Query: 183 DMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRK 242
               C+ W E   G F+ +   +  +ARRWG++K ++  M Y KL+RALR Y     + K
Sbjct: 325 SNSSCITW-EGTNGEFKMTDPDE--VARRWGERK-SKPNMNYDKLSRALRYYYDKNIMTK 380

Query: 243 VK-RKLTYQFD 252
           V  ++  Y+FD
Sbjct: 381 VHGKRYAYKFD 391


>gi|209954797 ets-related isoform 3 [Homo sapiens]
          Length = 486

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 5/131 (3%)

Query: 123 YPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRG 182
           +P+P     +  P   P  E    + D   + GP           +++L+QFLL LL+  
Sbjct: 272 HPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDS 331

Query: 183 DMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRK 242
               C+ W E   G F+ +   +  +ARRWG++K ++  M Y KL+RALR Y     + K
Sbjct: 332 SNSSCITW-EGTNGEFKMTDPDE--VARRWGERK-SKPNMNYDKLSRALRYYYDKNIMTK 387

Query: 243 VK-RKLTYQFD 252
           V  ++  Y+FD
Sbjct: 388 VHGKRYAYKFD 398


>gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]
          Length = 265

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 30/62 (48%), Positives = 41/62 (66%), Gaps = 3/62 (4%)

Query: 190 WVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTY 249
           W +   G+F+      E LA+ WGQ+K N  RMTY+KL+RALR Y KTG + +V R+L Y
Sbjct: 195 WEDREQGIFRVVKS--EALAKMWGQRKKN-DRMTYEKLSRALRYYYKTGILERVDRRLVY 251

Query: 250 QF 251
           +F
Sbjct: 252 KF 253


>gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]
          Length = 255

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 30/62 (48%), Positives = 41/62 (66%), Gaps = 3/62 (4%)

Query: 190 WVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTY 249
           W +   G+F+      E LA+ WGQ+K N  RMTY+KL+RALR Y KTG + +V R+L Y
Sbjct: 185 WEDREQGIFRVVKS--EALAKMWGQRKKN-DRMTYEKLSRALRYYYKTGILERVDRRLVY 241

Query: 250 QF 251
           +F
Sbjct: 242 KF 243


>gi|253683437 ets variant gene 1 isoform f [Homo sapiens]
          Length = 374

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 24/221 (10%)

Query: 51  PPVPATPYEAFDPAAAAFSHP------QAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPA 104
           PP+P  P E         S P      Q  +  Y  P Y     +  A S   P P +  
Sbjct: 95  PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIK 154

Query: 105 YPTENFASQTLVPPAYAPY-------PSPVLSEE---EDLP---LDSPALEVSDSESDEA 151
               +FA  + VP  ++ Y         P  +E    E  P    D   +     + D  
Sbjct: 155 QEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIK 214

Query: 152 LVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARR 211
              G   +G     R  L+L+QFL+ LL        + W   G    +F     E +ARR
Sbjct: 215 QEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG---MEFKLIEPEEVARR 271

Query: 212 WGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           WG QK NR  M Y KL+R+LR Y + G ++KV   +  Y+F
Sbjct: 272 WGIQK-NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 311


>gi|253683435 ets variant gene 1 isoform e [Homo sapiens]
          Length = 419

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 24/221 (10%)

Query: 51  PPVPATPYEAFDPAAAAFSHP------QAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPA 104
           PP+P  P E         S P      Q  +  Y  P Y     +  A S   P P +  
Sbjct: 140 PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIK 199

Query: 105 YPTENFASQTLVPPAYAPY-------PSPVLSEE---EDLP---LDSPALEVSDSESDEA 151
               +FA  + VP  ++ Y         P  +E    E  P    D   +     + D  
Sbjct: 200 QEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIK 259

Query: 152 LVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARR 211
              G   +G     R  L+L+QFL+ LL        + W   G    +F     E +ARR
Sbjct: 260 QEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG---MEFKLIEPEEVARR 316

Query: 212 WGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           WG QK NR  M Y KL+R+LR Y + G ++KV   +  Y+F
Sbjct: 317 WGIQK-NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 356


>gi|253683433 ets variant gene 1 isoform d [Homo sapiens]
          Length = 437

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 24/221 (10%)

Query: 51  PPVPATPYEAFDPAAAAFSHP------QAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPA 104
           PP+P  P E         S P      Q  +  Y  P Y     +  A S   P P +  
Sbjct: 158 PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIK 217

Query: 105 YPTENFASQTLVPPAYAPY-------PSPVLSEE---EDLP---LDSPALEVSDSESDEA 151
               +FA  + VP  ++ Y         P  +E    E  P    D   +     + D  
Sbjct: 218 QEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIK 277

Query: 152 LVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARR 211
              G   +G     R  L+L+QFL+ LL        + W   G    +F     E +ARR
Sbjct: 278 QEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG---MEFKLIEPEEVARR 334

Query: 212 WGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           WG QK NR  M Y KL+R+LR Y + G ++KV   +  Y+F
Sbjct: 335 WGIQK-NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 374


>gi|253683431 ets variant gene 1 isoform c [Homo sapiens]
          Length = 459

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 24/221 (10%)

Query: 51  PPVPATPYEAFDPAAAAFSHP------QAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPA 104
           PP+P  P E         S P      Q  +  Y  P Y     +  A S   P P +  
Sbjct: 180 PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIK 239

Query: 105 YPTENFASQTLVPPAYAPY-------PSPVLSEE---EDLP---LDSPALEVSDSESDEA 151
               +FA  + VP  ++ Y         P  +E    E  P    D   +     + D  
Sbjct: 240 QEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIK 299

Query: 152 LVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARR 211
              G   +G     R  L+L+QFL+ LL        + W   G    +F     E +ARR
Sbjct: 300 QEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG---MEFKLIEPEEVARR 356

Query: 212 WGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           WG QK NR  M Y KL+R+LR Y + G ++KV   +  Y+F
Sbjct: 357 WGIQK-NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 396


>gi|253683429 ets variant gene 1 isoform c [Homo sapiens]
          Length = 459

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 24/221 (10%)

Query: 51  PPVPATPYEAFDPAAAAFSHP------QAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPA 104
           PP+P  P E         S P      Q  +  Y  P Y     +  A S   P P +  
Sbjct: 180 PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIK 239

Query: 105 YPTENFASQTLVPPAYAPY-------PSPVLSEE---EDLP---LDSPALEVSDSESDEA 151
               +FA  + VP  ++ Y         P  +E    E  P    D   +     + D  
Sbjct: 240 QEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIK 299

Query: 152 LVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARR 211
              G   +G     R  L+L+QFL+ LL        + W   G    +F     E +ARR
Sbjct: 300 QEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG---MEFKLIEPEEVARR 356

Query: 212 WGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           WG QK NR  M Y KL+R+LR Y + G ++KV   +  Y+F
Sbjct: 357 WGIQK-NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 396


>gi|31742534 ets variant gene 1 isoform a [Homo sapiens]
          Length = 477

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 24/221 (10%)

Query: 51  PPVPATPYEAFDPAAAAFSHP------QAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPA 104
           PP+P  P E         S P      Q  +  Y  P Y     +  A S   P P +  
Sbjct: 198 PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIK 257

Query: 105 YPTENFASQTLVPPAYAPY-------PSPVLSEE---EDLP---LDSPALEVSDSESDEA 151
               +FA  + VP  ++ Y         P  +E    E  P    D   +     + D  
Sbjct: 258 QEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIK 317

Query: 152 LVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARR 211
              G   +G     R  L+L+QFL+ LL        + W   G    +F     E +ARR
Sbjct: 318 QEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG---MEFKLIEPEEVARR 374

Query: 212 WGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           WG QK NR  M Y KL+R+LR Y + G ++KV   +  Y+F
Sbjct: 375 WGIQK-NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 414


>gi|253683427 ets variant gene 1 isoform b [Homo sapiens]
          Length = 454

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 58/209 (27%), Positives = 81/209 (38%), Gaps = 23/209 (11%)

Query: 51  PPVPATPYEAFDPAAAAFSHP------QAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPA 104
           PP+P  P E         S P      Q  +  Y  P Y     +  A S   P P +  
Sbjct: 198 PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIK 257

Query: 105 YPTENFASQTLVPPAYAPYPSPVLSEEEDLPL-DSPALEVSDSESDEALVAGPEGKGSEA 163
               +FA           Y S  + E+      D   +     + D     G   +G   
Sbjct: 258 QEPRDFA-----------YDSGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTY 306

Query: 164 GTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMT 223
             R  L+L+QFL+ LL        + W   G    +F     E +ARRWG QK NR  M 
Sbjct: 307 QRRGSLQLWQFLVALLDDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMN 362

Query: 224 YQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           Y KL+R+LR Y + G ++KV   +  Y+F
Sbjct: 363 YDKLSRSLRYYYEKGIMQKVAGERYVYKF 391


>gi|219689118 v-ets erythroblastosis virus E26 oncogene homolog 1
           isoform 1 [Homo sapiens]
          Length = 485

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 29/157 (18%)

Query: 102 LPAYPTENFASQTLVPPAYAPYPSP------VLSEEEDLPLDSPALEVSDSESDEALVAG 155
           +P+Y  ++F S+    PA  P   P       + +  DL  D P +         A +AG
Sbjct: 324 VPSY--DSFDSEDY--PAALPNHKPKGTFKDYVRDRADLNKDKPVIPA-------AALAG 372

Query: 156 PEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQ 215
             G G        ++L+QFLL LLT    +  + W   G   ++F     + +ARRWG++
Sbjct: 373 YTGSGP-------IQLWQFLLELLTDKSCQSFISWTGDG---WEFKLSDPDEVARRWGKR 422

Query: 216 KGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           K N+ +M Y+KL+R LR Y     I K   ++  Y+F
Sbjct: 423 K-NKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 458


>gi|4885219 v-ets erythroblastosis virus E26 oncogene homolog 1
           isoform 2 [Homo sapiens]
          Length = 441

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 29/157 (18%)

Query: 102 LPAYPTENFASQTLVPPAYAPYPSP------VLSEEEDLPLDSPALEVSDSESDEALVAG 155
           +P+Y  ++F S+    PA  P   P       + +  DL  D P +         A +AG
Sbjct: 280 VPSY--DSFDSEDY--PAALPNHKPKGTFKDYVRDRADLNKDKPVIPA-------AALAG 328

Query: 156 PEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQ 215
             G G        ++L+QFLL LLT    +  + W   G   ++F     + +ARRWG++
Sbjct: 329 YTGSGP-------IQLWQFLLELLTDKSCQSFISWTGDG---WEFKLSDPDEVARRWGKR 378

Query: 216 KGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           K N+ +M Y+KL+R LR Y     I K   ++  Y+F
Sbjct: 379 K-NKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 414


>gi|241666446 v-ets erythroblastosis virus E26 oncogene homolog 1
           isoform 3 [Homo sapiens]
          Length = 225

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 29/157 (18%)

Query: 102 LPAYPTENFASQTLVPPAYAPYPSP------VLSEEEDLPLDSPALEVSDSESDEALVAG 155
           +P+Y  ++F S+    PA  P   P       + +  DL  D P +         A +AG
Sbjct: 64  VPSY--DSFDSEDY--PAALPNHKPKGTFKDYVRDRADLNKDKPVIPA-------AALAG 112

Query: 156 PEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQ 215
             G G        ++L+QFLL LLT    +  + W   G   ++F     + +ARRWG++
Sbjct: 113 YTGSGP-------IQLWQFLLELLTDKSCQSFISWTGDG---WEFKLSDPDEVARRWGKR 162

Query: 216 KGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           K N+ +M Y+KL+R LR Y     I K   ++  Y+F
Sbjct: 163 K-NKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 198


>gi|4885221 v-ets erythroblastosis virus E26 oncogene homolog 2
           [Homo sapiens]
          Length = 469

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 12/127 (9%)

Query: 126 PVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMR 185
           P +S ++ +   S  +E        A++AG  G G        ++L+QFLL LL+    +
Sbjct: 327 PTMSFKDYIQERSDPVEQGKPVIPAAVLAGFTGSGP-------IQLWQFLLELLSDKSCQ 379

Query: 186 ECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK- 244
             + W   G   ++F     + +ARRWG++K N+ +M Y+KL+R LR Y     I K   
Sbjct: 380 SFISWTGDG---WEFKLADPDEVARRWGKRK-NKPKMNYEKLSRGLRYYYDKNIIHKTSG 435

Query: 245 RKLTYQF 251
           ++  Y+F
Sbjct: 436 KRYVYRF 442


>gi|8923789 FEV (ETS oncogene family) [Homo sapiens]
          Length = 238

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 36/99 (36%), Positives = 56/99 (56%), Gaps = 6/99 (6%)

Query: 155 GPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQ 214
           GP     + G+ + ++L+QFLL LL       C+ W E G G F+ +   +  +ARRWG+
Sbjct: 34  GPLSPAVQKGSGQ-IQLWQFLLELLADRANAGCIAW-EGGHGEFKLTDPDE--VARRWGE 89

Query: 215 QKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQFD 252
           +K ++  M Y KL+RALR Y     + KV  ++  Y+FD
Sbjct: 90  RK-SKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFD 127


>gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]
          Length = 452

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)

Query: 147 ESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKE 206
           + D   + GP           +++L+QFLL LL+      C+ W E   G F+ +   + 
Sbjct: 259 QPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITW-EGTNGEFKMTDPDE- 316

Query: 207 LLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQFD 252
            +ARRWG++K ++  M Y KL+RALR Y     + KV  ++  Y+FD
Sbjct: 317 -VARRWGERK-SKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFD 361


>gi|223718207 ets variant gene 3 isoform 1 [Homo sapiens]
          Length = 512

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 17/115 (14%)

Query: 151 ALVAGPEGKG------------SEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVF 198
           ++V  PEG G            S  G+R+ ++L+ F+L LL + + R  + W +   G  
Sbjct: 6   SIVEKPEGGGGYQFPDWAYKTESSPGSRQ-IQLWHFILELLQKEEFRHVIAWQQGEYG-- 62

Query: 199 QFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQFD 252
           +F  K  + +AR WG++K  + +M Y KL+RALR Y     + K K ++ TY+F+
Sbjct: 63  EFVIKDPDEVARLWGRRKC-KPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFN 116


>gi|20270188 ets variant gene 3 isoform 2 [Homo sapiens]
          Length = 143

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 17/115 (14%)

Query: 151 ALVAGPEGKG------------SEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVF 198
           ++V  PEG G            S  G+R+ ++L+ F+L LL + + R  + W +   G  
Sbjct: 6   SIVEKPEGGGGYQFPDWAYKTESSPGSRQ-IQLWHFILELLQKEEFRHVIAWQQGEYG-- 62

Query: 199 QFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQFD 252
           +F  K  + +AR WG++K  + +M Y KL+RALR Y     + K K ++ TY+F+
Sbjct: 63  EFVIKDPDEVARLWGRRKC-KPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFN 116


>gi|166851840 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 6/97 (6%)

Query: 157 EGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVW-WVEPGAGVFQFSSKHKELLARRWGQQ 215
           EGK S+   R    L++F+  +L   ++ E +  W     GVF+F     E +A+ WGQ+
Sbjct: 262 EGKKSKHAPRGT-HLWEFIRDILIHPELNEGLMKWENRHEGVFKFL--RSEAVAQLWGQK 318

Query: 216 KGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           K N   MTY+KL+RA+R Y K   + +V  R+L Y+F
Sbjct: 319 KKN-SNMTYEKLSRAMRYYYKREILERVDGRRLVYKF 354


>gi|167235023 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 6/97 (6%)

Query: 157 EGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVW-WVEPGAGVFQFSSKHKELLARRWGQQ 215
           EGK S+   R    L++F+  +L   ++ E +  W     GVF+F     E +A+ WGQ+
Sbjct: 262 EGKKSKHAPRGT-HLWEFIRDILIHPELNEGLMKWENRHEGVFKFL--RSEAVAQLWGQK 318

Query: 216 KGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           K N   MTY+KL+RA+R Y K   + +V  R+L Y+F
Sbjct: 319 KKN-SNMTYEKLSRAMRYYYKREILERVDGRRLVYKF 354


>gi|187608767 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 33/98 (33%), Positives = 55/98 (56%), Gaps = 5/98 (5%)

Query: 156 PEGKGSEAGTRKKLRLYQFLLGLLT-RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQ 214
           P  K S+ G    + L++FLL LL  R    + + W +   G+F+      + +++ WG+
Sbjct: 196 PIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDS--KAVSKLWGK 253

Query: 215 QKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           QK N+  M Y+ + RALR Y + G + KV+ ++L YQF
Sbjct: 254 QK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 290


>gi|4503555 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 33/98 (33%), Positives = 55/98 (56%), Gaps = 5/98 (5%)

Query: 156 PEGKGSEAGTRKKLRLYQFLLGLLT-RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQ 214
           P  K S+ G    + L++FLL LL  R    + + W +   G+F+      + +++ WG+
Sbjct: 196 PIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDS--KAVSKLWGK 253

Query: 215 QKGNRKRMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 251
           QK N+  M Y+ + RALR Y + G + KV+ ++L YQF
Sbjct: 254 QK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 290


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,516,200
Number of Sequences: 37866
Number of extensions: 729115
Number of successful extensions: 3722
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 301
Number of HSP's that attempted gapping in prelim test: 3349
Number of HSP's gapped (non-prelim): 617
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.