Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 13569879

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 1 [Homo sapiens]
         (268 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...   535   e-152
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   440   e-124
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   414   e-116
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   298   4e-81
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   296   1e-80
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]           235   3e-62
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...   230   9e-61
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...   230   9e-61
gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]          170   1e-42
gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]          163   2e-40
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    86   3e-17
gi|21735415 centromere protein B [Homo sapiens]                        76   4e-14
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              76   4e-14
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    74   1e-13
gi|55956788 nucleolin [Homo sapiens]                                   74   1e-13
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          72   4e-13
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  69   3e-12
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    68   7e-12
gi|4504487 histidine rich calcium binding protein precursor [Hom...    67   1e-11
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               67   2e-11
gi|115529449 upstream binding transcription factor, RNA polymera...    67   2e-11
gi|115529451 upstream binding transcription factor, RNA polymera...    67   2e-11
gi|7657671 upstream binding transcription factor, RNA polymerase...    67   2e-11
gi|221219020 NYD-SP11 protein [Homo sapiens]                           66   3e-11
gi|210032580 SET domain containing 1B [Homo sapiens]                   66   3e-11
gi|31621309 leucine rich repeat containing 6 [Homo sapiens]            66   3e-11
gi|22749303 hypothetical protein LOC196477 [Homo sapiens]              65   5e-11
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       65   6e-11
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       65   6e-11
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        65   6e-11

>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score =  535 bits (1378), Expect = e-152
 Identities = 268/268 (100%), Positives = 268/268 (100%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
           PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
Sbjct: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120

Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
           FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
Sbjct: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180

Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
           PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
Sbjct: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240

Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
           EEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 241 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 268


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score =  440 bits (1132), Expect = e-124
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 49  MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA 108
           MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA
Sbjct: 1   MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA 60

Query: 109 LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE 168
           LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE
Sbjct: 61  LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE 120

Query: 169 DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD 228
           DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD
Sbjct: 121 DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD 180

Query: 229 EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
           EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 181 EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score =  414 bits (1064), Expect = e-116
 Identities = 219/268 (81%), Positives = 222/268 (82%), Gaps = 41/268 (15%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVE      L
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVE------L 54

Query: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
            SL +L  L                            NK++        QNLKNLKSLDL
Sbjct: 55  SSLARLPSL----------------------------NKLRK-------QNLKNLKSLDL 79

Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
           FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
Sbjct: 80  FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139

Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
           PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
Sbjct: 140 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 199

Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
           EEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 200 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 227


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score =  298 bits (762), Expect = 4e-81
 Identities = 158/267 (59%), Positives = 204/267 (76%), Gaps = 18/267 (6%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEM ++I+LELRNR+P +V ELVLDN     G++EGL D F+ELEFLS  NV L+S+A L
Sbjct: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60

Query: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
           P LNKL+KLELSDN +SGGLEVLAEKCPNLT+LNLSGNKIKDLST+E L+ L+NLKSLDL
Sbjct: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120

Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
           FNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E   +G  DDEEE+E+E   
Sbjct: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 179

Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
            E  +  E+EE+E++E+E E+ED +G    E E+E G +     E+ DEED++   E GE
Sbjct: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEEDEE---ELGE 230

Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
           EE        RG+KRKR+ ED+GE++D
Sbjct: 231 EE--------RGQKRKREPEDEGEDDD 249


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score =  296 bits (759), Expect = 1e-80
 Identities = 155/266 (58%), Positives = 202/266 (75%), Gaps = 15/266 (5%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           M+MK++I+LELRNR+P  V ELVLDNC   +G+IEGL   F  LEFLS+ NV L S++ L
Sbjct: 1   MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 60

Query: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
           P L KL+KLELS+N I GGL++LAEK PNLT+LNLSGNK+KD+ST+E L+ L+ LKSLDL
Sbjct: 61  PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 120

Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
           FNCE+TNL DYRES+F+LL Q+TYLDG+D+ED EAPDS+ E D   +E+++EE E+E   
Sbjct: 121 FNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDE 180

Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
            +   EEEE +EE+DEDED + DE   E+ E EEE GL         DEED+D+     +
Sbjct: 181 DDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGL---------DEEDEDE-----D 226

Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEE 266
           E+EEEEEGG +GEKRKR+ +D+GE++
Sbjct: 227 EDEEEEEGG-KGEKRKRETDDEGEDD 251


>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
          Length = 234

 Score =  235 bits (600), Expect = 3e-62
 Identities = 139/256 (54%), Positives = 175/256 (68%), Gaps = 22/256 (8%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEM ++I+ ELRNR+P +V EL LDN     G++E L D F+ELEFLS  N  L+S++ L
Sbjct: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60

Query: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
           P L KLRKLEL    +SGGLEVLAEKCPNLT+L LSGNKIKDLST+E L+ L+NLKSLDL
Sbjct: 61  PKL-KLRKLELR---VSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116

Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
           FNCE+TNL DY E++F+LL Q+TYLD    +  EAP S+ ED  +G  DDEEE E+E   
Sbjct: 117 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEG-LDDEEEGEHEEEY 175

Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
            E  +  E+EE EE+E+E E+ED +G     G+EE            DEE  +D   +GE
Sbjct: 176 DEDAQVVEDEEGEEEEEEGEEEDVSG-----GDEE------------DEEGYNDGEVDGE 218

Query: 241 EEEEEEEGGLRGEKRK 256
           E+EEE     RG+KRK
Sbjct: 219 EDEEELGEEERGQKRK 234



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 225 EIQDEEDDDDYVEEGEEEEE-EEEGGLRGEKRKRDAEDDGEEED 267
           +I+D  +  D  EEGE EEE +E+  +  ++   + E++GEEED
Sbjct: 155 DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEED 198


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  230 bits (587), Expect = 9e-61
 Identities = 130/254 (51%), Positives = 171/254 (67%), Gaps = 25/254 (9%)

Query: 15  SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDN 74
           S   V E VLDNC   + +IE L   F  LEFL + NV L S++ LP L KL+K  LS+N
Sbjct: 35  SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94

Query: 75  IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRES 134
            I GGL + AEK PNLT+LNLSG K+KD+ST+E L+ L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95  RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154

Query: 135 IFELLQQITYLDGFDQEDNEAPDSE------EEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
           +F+LL Q+T LD +D ED EAPDS+      ++++ED + +DE++ ENE G      EEE
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDG------EEE 208

Query: 189 EEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG 248
           E +EEEDEDED + D+   E+ E EEE GL        +DE+D+D    E E+EEEEE G
Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD-------KDEDDED----EDEDEEEEESG 257

Query: 249 GLRGEKRKRDAEDD 262
             +GE RKR+ +D+
Sbjct: 258 --KGENRKRETDDE 269


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  230 bits (587), Expect = 9e-61
 Identities = 130/254 (51%), Positives = 171/254 (67%), Gaps = 25/254 (9%)

Query: 15  SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDN 74
           S   V E VLDNC   + +IE L   F  LEFL + NV L S++ LP L KL+K  LS+N
Sbjct: 35  SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94

Query: 75  IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRES 134
            I GGL + AEK PNLT+LNLSG K+KD+ST+E L+ L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95  RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154

Query: 135 IFELLQQITYLDGFDQEDNEAPDSE------EEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
           +F+LL Q+T LD +D ED EAPDS+      ++++ED + +DE++ ENE G      EEE
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDG------EEE 208

Query: 189 EEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG 248
           E +EEEDEDED + D+   E+ E EEE GL        +DE+D+D    E E+EEEEE G
Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD-------KDEDDED----EDEDEEEEESG 257

Query: 249 GLRGEKRKRDAEDD 262
             +GE RKR+ +D+
Sbjct: 258 --KGENRKRETDDE 269


>gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
          Length = 131

 Score =  170 bits (430), Expect = 1e-42
 Identities = 86/131 (65%), Positives = 104/131 (79%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEM K I+LELRNR+P +V EL LDN     G++EGL D F+ELE L+  N+ L+S+A L
Sbjct: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60

Query: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
           P LNKL+KLELS N  S GLEVLAEKCPNL +LNLSGNKIKDLST+E L+ L+NL+SLDL
Sbjct: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120

Query: 121 FNCEITNLEDY 131
           F CE+TNL +Y
Sbjct: 121 FTCEVTNLNNY 131


>gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]
          Length = 450

 Score =  163 bits (412), Expect = 2e-40
 Identities = 93/185 (50%), Positives = 119/185 (64%), Gaps = 6/185 (3%)

Query: 15  SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDN 74
           S   V E VLDNC   + +IE L   F  LEFL + NV L S++ LP L KL+K  LS+N
Sbjct: 35  SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94

Query: 75  IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRES 134
            I GGL + AEK PNLT+LNLSG K+KD+ST+E L+ L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95  RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154

Query: 135 IFELLQQITYLDGFDQEDNEAPDSEEE--DDEDGDEDDEEEE----ENEAGPPEGYEEEE 188
           +F+LL Q+T LD +D ED EAPDS+ +   D  G E           + A PPE     +
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQLLADPWGKEYHTNNAPLLLRSPAWPPEPSIRPQ 214

Query: 189 EEEEE 193
           E++ E
Sbjct: 215 EQDYE 219


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 51/126 (40%), Positives = 76/126 (60%), Gaps = 6/126 (4%)

Query: 145 LDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
           ++G + E+ +    EEE++ +G+E++ E EE E    EG EEE E + EE+ +E E E+E
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG---EGEEEEGEGKGEEEGEEGEGEEE 870

Query: 205 AGSELGEGEEEVGLSYLMKE---EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAED 261
                GEGEEE G     +E   E ++EE + +  EEGE E EEEEG  +GE+   + E 
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930

Query: 262 DGEEED 267
           +GEEE+
Sbjct: 931 EGEEEE 936



 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 57/126 (45%), Positives = 73/126 (57%), Gaps = 9/126 (7%)

Query: 151  EDNEAPDSEEEDDEDGDEDDEEEE---ENEAGPPEGYEEEEE----EEEEEDEDEDEDED 203
            E+ E     EE+ E+G+ + EEEE   E E G  EG EEE E    EEE E E E+E E 
Sbjct: 913  EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972

Query: 204  EAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE-EEEEEEEGGLRGEKRKRDAED 261
            E     GEGEEE G     +EE ++E E++ +  EEGE E EEEEEG + GE    + E 
Sbjct: 973  EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032

Query: 262  DGEEED 267
            +GEEE+
Sbjct: 1033 EGEEEE 1038



 Score = 84.7 bits (208), Expect = 8e-17
 Identities = 55/125 (44%), Positives = 73/125 (58%), Gaps = 9/125 (7%)

Query: 151  EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED--EAGSE 208
            ED E    EEE + +G+E++ E E  E G  EG E E E EEEE E E E+E+  E G E
Sbjct: 942  EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001

Query: 209  LGEGEEEVGLSYLMKEE--IQDEEDDDDYVEEGEEEEEEEEGGLR-----GEKRKRDAED 261
             GEGEEE       +EE  ++ E + ++   EGEEEE EEEG  R     GE+ +R+ E+
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE 1061

Query: 262  DGEEE 266
            + EEE
Sbjct: 1062 EEEEE 1066



 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 53/118 (44%), Positives = 68/118 (57%), Gaps = 5/118 (4%)

Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE-EEEEDEDEDEDEDEAGSEL 209
           E+ E    EEE + +G+E+ E E E E G  EG EE E E EEEE E + E+E E G   
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE-- 929

Query: 210 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
           GEGEEE G       E + EE++ ++  EGEEEE E EG   GE    + E +GEEE+
Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEGEW--EGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985



 Score = 81.3 bits (199), Expect = 8e-16
 Identities = 51/122 (41%), Positives = 70/122 (57%), Gaps = 11/122 (9%)

Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
           +G  +E+ E    EEE + +G+E+ E E E E G  +G EE EE E E +E+E E E E 
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943

Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
           G   GEGEEE G     + E ++EE + +  EEGE E EE EG    E  + + E +GEE
Sbjct: 944 GE--GEGEEEEG-----EWEGEEEEGEGEGEEEGEGEGEEGEG----EGEEEEGEGEGEE 992

Query: 266 ED 267
           E+
Sbjct: 993 EE 994



 Score = 79.0 bits (193), Expect = 4e-15
 Identities = 52/118 (44%), Positives = 68/118 (57%), Gaps = 6/118 (5%)

Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
           +E+ +  + EEE+ E   E+ EE  E E G  E  + E EEEEEE E E+E E E   E 
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE-EGEGEEEE 846

Query: 210 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
           GEGEEE G      EE  +E + ++  EEGE E EEEEG   GE+   + E +GEEE+
Sbjct: 847 GEGEEEEGEG--KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE---EGEGEGEEEE 899



 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 52/132 (39%), Positives = 73/132 (55%), Gaps = 11/132 (8%)

Query: 146  DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYE-------EEEEEEEEEDEDE 198
            +G  +E+    + EEE + +G+E++ E E  E G  EG E       EEE EE E + +E
Sbjct: 875  EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934

Query: 199  DEDEDEAGSELGEGEEEVGLSYLMKE--EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 256
            +E E E     GEGEEE G     +E  E + EE+ +   EEGE E EEEEG   GE  +
Sbjct: 935  EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG--EGEGEE 992

Query: 257  RDAEDDGEEEDD 268
             + E++GEEE +
Sbjct: 993  EEGEEEGEEEGE 1004



 Score = 77.8 bits (190), Expect = 9e-15
 Identities = 56/120 (46%), Positives = 67/120 (55%), Gaps = 13/120 (10%)

Query: 151 EDNEAPDSEEEDDEDGDEDDEE---EEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
           E+ E    EEE +  G+E+ EE   EEE E G  EG EEEE E E E+E E E E+E G 
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG-EEEEGEGEGEEEGEGEGEEEEGE 901

Query: 208 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
             GEGEEE        EE + E   ++  EEGE E EEEEG   GE    D E +GEEE+
Sbjct: 902 --GEGEEE---GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE----DGEGEGEEEE 952



 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 53/131 (40%), Positives = 71/131 (54%), Gaps = 23/131 (17%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEA--------GPPEGYEEEE---EEEEEEDED 197
           +++  E    EE+ +E+GD+ + EEEE E         G  EG E EE   E EEEE+E 
Sbjct: 774 ERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833

Query: 198 EDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKR 257
           E E+E+      GEGEEE G      EE + E   ++  EEGE EEE EEG   GE  + 
Sbjct: 834 EGEEEE------GEGEEEEGEG----EEEEGEGKGEEEGEEGEGEEEGEEG--EGEGEEE 881

Query: 258 DAEDDGEEEDD 268
           + E +GEEE +
Sbjct: 882 EGEGEGEEEGE 892



 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 18/129 (13%)

Query: 146  DGFDQEDNEAPDSEEE-DDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
            +G ++ + E  + E E ++E+G+ + EEEE  E G  EG  EEE E E E+E+E E E E
Sbjct: 965  EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024

Query: 205  AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE--------EEEEEEEGGLRGEKRK 256
               E GEGE E         E + EE+ ++  +EGE        EEEEEEEG  +    +
Sbjct: 1025 VEGEEGEGEGE---------EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEE 1075

Query: 257  RDAEDDGEE 265
             +   DGEE
Sbjct: 1076 ENERQDGEE 1084



 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 57/160 (35%), Positives = 84/160 (52%), Gaps = 17/160 (10%)

Query: 124 EITNLEDYRESIFELLQQITYLDGFDQEDNEAPDS--EEE----DDEDGDEDDEEEEENE 177
           E+   E++++   E  +Q     G  +E N+  +   EEE    ++E+GD ++EEE+E E
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754

Query: 178 AGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE--------LGEGEEEVGLSYLMKEEIQDE 229
            G  EG  EE E E E++E E + E+ AG E         GEGEEE       ++E   E
Sbjct: 755 -GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813

Query: 230 EDDDDYVE-EGEEEEEEEEG-GLRGEKRKRDAEDDGEEED 267
            +  +  E +GE EEEEEEG G   E    + E +GEEE+
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853



 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 47/123 (38%), Positives = 66/123 (53%), Gaps = 10/123 (8%)

Query: 149 DQEDNEAPDSE---EEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
           DQ + E  ++E   EE +E G+ +  E EE +    E  EE E EEEE + +E+E E E 
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851

Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
               G+GEEE        EE + EE+ ++   EGEEEE E EG   GE    + E +GE 
Sbjct: 852 EEGEGKGEEE-------GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG 904

Query: 266 EDD 268
           E++
Sbjct: 905 EEE 907



 Score = 71.2 bits (173), Expect = 9e-13
 Identities = 48/121 (39%), Positives = 69/121 (57%), Gaps = 11/121 (9%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEE-ENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
           ++E+ E    EE ++ +G+E+ EE E E E    EG  EEE E E E+E+ + + +E G 
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE 909

Query: 208 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG-GLRGEKRKRDAEDDGEEE 266
             GEGEEE G       E + EE+ ++   EGEEEE E EG    GE  + + E +GEEE
Sbjct: 910 --GEGEEEEG-------EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960

Query: 267 D 267
           +
Sbjct: 961 E 961



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 44/130 (33%), Positives = 70/130 (53%), Gaps = 11/130 (8%)

Query: 149 DQEDNEAPDSEEEDDEDGDE--DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED--- 203
           D+E+ E  + E +++ +G+E   + E+EE E    E   +EE+ EEE D+ E E+E+   
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803

Query: 204 -----EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRD 258
                E G E+  GE E G     +EE + E ++++   E EE E EEE G  G+  +  
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG-EGKGEEEG 862

Query: 259 AEDDGEEEDD 268
            E +GEEE +
Sbjct: 863 EEGEGEEEGE 872



 Score = 64.7 bits (156), Expect = 8e-11
 Identities = 47/129 (36%), Positives = 66/129 (51%), Gaps = 12/129 (9%)

Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE---EEEEDEDEDEDEDEAGS 207
           E  E  + EE + E   E+ E ++E  AG  E  EEE ++   EEEE E   E+++E G 
Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813

Query: 208 -ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL--------RGEKRKRD 258
            E GE EE  G     +EE + EE++ +  EE  E EEEE  G          GE+   +
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873

Query: 259 AEDDGEEED 267
            E +GEEE+
Sbjct: 874 GEGEGEEEE 882



 Score = 61.2 bits (147), Expect = 9e-10
 Identities = 42/126 (33%), Positives = 64/126 (50%), Gaps = 12/126 (9%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAG-- 206
           ++E  E      E +  G+ + E  E+ E    +G E+E++E E+  + E   E E G  
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE 732

Query: 207 SELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE----EEEEEEEGGLRGEKRKRDAEDD 262
            E GEGEEE G      +  ++EE + +  EEGE    E E E+E G R ++ +   E+ 
Sbjct: 733 EEHGEGEEEEG------DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786

Query: 263 GEEEDD 268
           GEEE D
Sbjct: 787 GEEEGD 792



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 42/130 (32%), Positives = 70/130 (53%), Gaps = 27/130 (20%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEE--EEEEEEEDEDEDEDEDEAG 206
           ++E+ +  D EE++ ++ ++  ++E   E    EG EEE  E EEEE D +E+E+++  G
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEM--EEGGEEEHGEGEEEEGDREEEEEKEGEG 755

Query: 207 SELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE--------EEGGLRGEKRKRD 258
            E GEGEE           ++ E +     EEGE ++EE        EE G +GE  + +
Sbjct: 756 KEEGEGEE-----------VEGEREK----EEGERKKEERAGKEEKGEEEGDQGEGEEEE 800

Query: 259 AEDDGEEEDD 268
            E  GEE+++
Sbjct: 801 TEGRGEEKEE 810



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 17/146 (11%)

Query: 138 LLQQITYLDGFDQEDNEAPDSEE--EDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEED 195
           + Q  T ++ F  E+ E P+ +E  ED +    +++E E NE         +E+ E   D
Sbjct: 569 MTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSD 628

Query: 196 EDEDEDEDEAGSELGEGEEEVG----------LSYLMKEEIQDEEDDDDYVEEGEEE--- 242
           +  D+ E   G     GE E G                E  QDEE +    ++G  E   
Sbjct: 629 DLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER 688

Query: 243 --EEEEEGGLRGEKRKRDAEDDGEEE 266
             E E+E   + E +KRD E+  ++E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKE 714



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 13/119 (10%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
           D   ++A  SE +    G+ +D  E   +    EG    E  ++EE E  ++D+     E
Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687

Query: 209 L-GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
             GEGE+E+      KEE +  + ++      +E++E E+G    ++R ++ E+ GEEE
Sbjct: 688 RPGEGEKELA----EKEEWKKRDGEE------QEQKEREQG--HQKERNQEMEEGGEEE 734


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)

Query: 143 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 198
           T L    +E+ E  + EEE++ +G+E++E  EEEE E G  E  G EEE EEE + D DE
Sbjct: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458

Query: 199 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 239
           +E+EDE  S  G       +G  E G S   Y  +EE Q          E+ D D  EE 
Sbjct: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518

Query: 240 EEEEEEEEGGLRGEKRKRDAEDDGEEED 267
           +EEE++E           D +DD +EED
Sbjct: 519 DEEEDDE-----------DEDDDDDEED 535



 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)

Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 203
           +G ++E+ E  + EEE + + +E++ EEEE E G  E  G EEE EEE + D DE+E+ED
Sbjct: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463

Query: 204 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 244
           E  S  G       +G  E G S   Y  +EE Q          E+ D D  EE +EEE+
Sbjct: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523

Query: 245 EEEGGLRGEKRKRDAEDDGEEEDD 268
           +E+            EDD ++E+D
Sbjct: 524 DED------------EDDDDDEED 535



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)

Query: 147 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 181
           G  +E  E  + EEE D D DE++EE+EE+               EAG            
Sbjct: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496

Query: 182 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
                   EG E+ + + EEED++E++DEDE   +  E  +EV
Sbjct: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)

Query: 144 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 181
           +L+G +  D+  E  D EEEDDED D+DD+EE+ +E   P
Sbjct: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 65/187 (34%), Positives = 99/187 (52%), Gaps = 32/187 (17%)

Query: 37  LND-TFKELEFLSMANVELSSLARLPSLNKLRKLELSDNII-SGGLEVLAEKC----PNL 90
           LND TF E   ++MA         L +L ++  +   D ++ S G   +A+      P L
Sbjct: 243 LNDNTFTEKGAVAMAET-------LKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKL 295

Query: 91  TYLNLSGNKIKD---LSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDG 147
             LNLS  +IK    L+  EA+ +   L+ LDL      N     E   E LQ++  L+G
Sbjct: 296 KELNLSFCEIKRDAALAVAEAMADKAELEKLDL------NGNTLGEEGCEQLQEV--LEG 347

Query: 148 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
           F+     A  S++ED+E+ +E +EEEEE E        EEEEE+EEE+E+E+E+E+E   
Sbjct: 348 FNMAKVLASLSDDEDEEEEEEGEEEEEEAE--------EEEEEDEEEEEEEEEEEEEEPQ 399

Query: 208 ELGEGEE 214
           + G+GE+
Sbjct: 400 QRGQGEK 406



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 64/212 (30%), Positives = 99/212 (46%), Gaps = 39/212 (18%)

Query: 54  LSSLARLPSLNKL-RKLELSDNIISG-GLEVLAEKCPNLTY---LNLSGNKIKDLSTV-- 106
           +++LA+  ++N L R + L+DN  +  G   +AE    L     +N     ++    V  
Sbjct: 225 ITALAQAFAVNPLLRVINLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAI 284

Query: 107 -EALQN-LKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDE 164
            +A++  L  LK L+L  CEI    D   ++ E +     L+  D   N           
Sbjct: 285 ADAIRGGLPKLKELNLSFCEIKR--DAALAVAEAMADKAELEKLDLNGNTL--------- 333

Query: 165 DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKE 224
            G+E  E+ +E      EG+   +      D DEDE+E+E      EGEEE       +E
Sbjct: 334 -GEEGCEQLQE----VLEGFNMAKVLASLSD-DEDEEEEE------EGEEE-------EE 374

Query: 225 EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 256
           E ++EE++D+  EE EEEEEEEE   RG+  K
Sbjct: 375 EAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 4/82 (4%)

Query: 191 EEEEDEDEDEDEDEAGSELGEGE----EEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 246
           E   D+ E E  D  G+ LGE      +EV   + M + +    DD+D  EE E EEEEE
Sbjct: 315 EAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEE 374

Query: 247 EGGLRGEKRKRDAEDDGEEEDD 268
           E     E+ + + E++ EEE++
Sbjct: 375 EAEEEEEEDEEEEEEEEEEEEE 396



 Score = 34.7 bits (78), Expect = 0.090
 Identities = 22/82 (26%), Positives = 44/82 (53%), Gaps = 5/82 (6%)

Query: 187 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 246
           ++ E E+ D + +   +E   +L E  E   ++ ++     DE+++++   E EEEE EE
Sbjct: 319 DKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEE 378

Query: 247 EGGLRGEKRKRDAEDDGEEEDD 268
           E     E+   + E++ EEE++
Sbjct: 379 E-----EEEDEEEEEEEEEEEE 395


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 43/97 (44%), Positives = 62/97 (63%), Gaps = 12/97 (12%)

Query: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
           D EEE++E+ +E++EEEEE E    E +EEEEE+EEE  E+E+E+E+E   E  E E E+
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEE----EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942

Query: 217 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
                   E ++EE+D++  EE EE E+ E G   GE
Sbjct: 943 --------EEEEEEEDEEEEEELEEVEDLEFGTAGGE 971



 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 45/99 (45%), Positives = 59/99 (59%), Gaps = 20/99 (20%)

Query: 156 PDSEEED-------DEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
           P + EED         D +E++EEEEE E       EEEEEEEEE+ E+E+EDE+E   E
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEE-------EEEEEEEEEDFEEEEEDEEEYFEE 923

Query: 209 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
             E EEE       +EE ++EE + +  EE E+EEEEEE
Sbjct: 924 EEEEEEE------FEEEFEEEEGELEEEEEEEDEEEEEE 956



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 35/76 (46%), Positives = 50/76 (65%), Gaps = 1/76 (1%)

Query: 187 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY-VEEGEEEEEE 245
           +EEEEEEE+E+E+E+E+E   E  E EEE    Y  +EE ++EE ++++  EEGE EEEE
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 246 EEGGLRGEKRKRDAED 261
           EE     E+   + ED
Sbjct: 947 EEEDEEEEEELEEVED 962



 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 33/84 (39%), Positives = 48/84 (57%), Gaps = 22/84 (26%)

Query: 185 EEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244
           EEEEEEEEEE+E+E+E+E+E                   E+ ++EE+D+   EE  EEEE
Sbjct: 888 EEEEEEEEEEEEEEEEEEEE-------------------EDFEEEEEDE---EEYFEEEE 925

Query: 245 EEEGGLRGEKRKRDAEDDGEEEDD 268
           EEE     E  + + E + EEE++
Sbjct: 926 EEEEEFEEEFEEEEGELEEEEEEE 949



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 10/116 (8%)

Query: 149  DQEDNEAPDSEEEDDEDGDEDDEEEEEN---EAGPPEGY---EEEEEEEEEEDEDEDEDE 202
            ++E+ E  + EEED+E+  E++EEEEE    E    EG    EEEEE+EEEE+E E+ ++
Sbjct: 903  EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962

Query: 203  DEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE----EEEEGGLRGEK 254
             E G+  GE EE       +   +   E       E E E     E EE G   E+
Sbjct: 963  LEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEER 1018



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEE-DEDEDEDEDE 204
           + F++E+ +  +  EE++E+ +E +EE EE E    E  EEE+EEEEEE +E ED +   
Sbjct: 908 EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGT 967

Query: 205 AGSELGEG 212
           AG E+ EG
Sbjct: 968 AGGEVEEG 975



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 18/56 (32%), Positives = 35/56 (62%)

Query: 213 EEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
           EE++ +  +   + ++EE++++  EE EEEEEEE+     E  +   E++ EEE++
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 6/63 (9%)

Query: 149  DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
            ++E +  P   EE+ EDG +  +   E  A      EEE E E E +  +++++D+  + 
Sbjct: 1055 EEEPSAPPTLLEEETEDGSDKVQPPPETPA------EEEMETETEAEALQEKEQDDTAAM 1108

Query: 209  LGE 211
            L +
Sbjct: 1109 LAD 1111



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 6/83 (7%)

Query: 157  DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEE------EDEDEDEDEDEAGSELG 210
            + E E    G    E  EE  + PP   EEE E+  +      E   E+E E E  +E  
Sbjct: 1038 EREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL 1097

Query: 211  EGEEEVGLSYLMKEEIQDEEDDD 233
            + +E+   + ++ + I    DD+
Sbjct: 1098 QEKEQDDTAAMLADFIDCPPDDE 1120



 Score = 28.9 bits (63), Expect = 4.9
 Identities = 29/97 (29%), Positives = 39/97 (40%), Gaps = 19/97 (19%)

Query: 154  EAPDSEEEDDEDG------------DEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDED 201
            E P +EEE   D              E + E E   AGPP   +E  EEE        E+
Sbjct: 1010 EEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPP--QELVEEEPSAPPTLLEE 1067

Query: 202  EDEAGSELGEGEEEVGLSYLMK-----EEIQDEEDDD 233
            E E GS+  +   E      M+     E +Q++E DD
Sbjct: 1068 ETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 41/135 (30%), Positives = 70/135 (51%), Gaps = 25/135 (18%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
           +  D E  D  EED+ED +++DE+E+E E    +        E+E+DED+++DED+   E
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202

Query: 209 LGEGEEE---------------VGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
             + EEE               V +      E +DEE+DD+  ++ ++E++E++      
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD------ 256

Query: 254 KRKRDAEDDGEEEDD 268
               D EDD EEE++
Sbjct: 257 ----DDEDDEEEEEE 267



 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 40/138 (28%), Positives = 77/138 (55%), Gaps = 30/138 (21%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEE----ENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
           D+E+++  + +EEDDED DED++E E    +  A  P   +E++E++E++++D+D++ED+
Sbjct: 146 DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDD 205

Query: 205 AGSELGEGEEEVGLSYLM--------------KEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
           +  E  E     G                   +EE  ++EDDDD  +E +E++++E+   
Sbjct: 206 SEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD--DEDDEDDDDED--- 260

Query: 251 RGEKRKRDAEDDGEEEDD 268
                  D E++ EEE++
Sbjct: 261 -------DEEEEEEEEEE 271



 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 30/128 (23%)

Query: 156 PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-------AGSE 208
           P    ++ ++  ++D +EEE++       + EE+EE++EDEDEDEDE E       A + 
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDD-------DSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP 182

Query: 209 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE--------KRKRDAE 260
             E E++        E+ +D+EDDDD  E+  EEE  E    +G+        K K  AE
Sbjct: 183 ASEDEDD--------EDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234

Query: 261 DDGEEEDD 268
           D+ EEEDD
Sbjct: 235 DEDEEEDD 242



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 39/129 (30%), Positives = 69/129 (53%), Gaps = 29/129 (22%)

Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE------EEEEEEDEDEDEDED 203
           +++++  D ++EDD+D +EDD EEE  E  P +G +  +      +   E++++E++DED
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244

Query: 204 EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE------GGLRGEKRKR 257
           E                   ++ +D+EDDDD  +E EEEEEEEE      G  + E  K+
Sbjct: 245 ED-----------------DDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287

Query: 258 DAEDDGEEE 266
            A  + +++
Sbjct: 288 KAAPEAKKQ 296



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 30/109 (27%), Positives = 54/109 (49%), Gaps = 24/109 (22%)

Query: 146 DGFDQEDNEAPDSEEE------------------------DDEDGDEDDEEEEENEAGPP 181
           D  D +D+E  DSEEE                        +DED +EDDE+E++++    
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD 253

Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 230
           E  ++E++EEEEE+E+E+  ++  G    E  ++       K++++  E
Sbjct: 254 EDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302



 Score = 31.6 bits (70), Expect = 0.76
 Identities = 14/40 (35%), Positives = 26/40 (65%), Gaps = 3/40 (7%)

Query: 170 DEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
           ++ + +  A PP+   E EE+ E+E+  EDE++D +G E+
Sbjct: 10  NQGDPKKMAPPPK---EVEEDSEDEEMSEDEEDDSSGEEV 46



 Score = 28.1 bits (61), Expect = 8.4
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 179 GPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGE 211
           G P+      +E EE+ EDE+  EDE     GE
Sbjct: 12  GDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGE 44


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 47/123 (38%), Positives = 64/123 (52%), Gaps = 23/123 (18%)

Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
           DG +  D +  D  EE  ED DE  +E+EE+E    EG  EEEEE EEEDED+DED    
Sbjct: 94  DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE----EGDREEEEEIEEEDEDDDED---- 145

Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
               GE  E+        EE ++EE+++   EE EEE E+ +      +  +D E D   
Sbjct: 146 ----GEDVED--------EEEEEEEEEE---EEEEEENEDHQMNCHNTRIMQDTEKDDNN 190

Query: 266 EDD 268
            D+
Sbjct: 191 NDE 193



 Score = 64.7 bits (156), Expect = 8e-11
 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%)

Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 210
           EDN+ P  E+E+DE+GD ++EEE E E    +  E+ E+ E+EE+E+E+E+E+E   E  
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169

Query: 211 EGEEEVGLSYLMKEEIQDEEDDDDY 235
           + +     + +M++  +D+ ++D+Y
Sbjct: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 36/110 (32%), Positives = 51/110 (46%), Gaps = 35/110 (31%)

Query: 159 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 218
           +E DD DG ED +E+EE+E            EE  ED DE  DEDE              
Sbjct: 88  DECDDSDGTEDMDEKEEDEG-----------EEYSEDNDEPGDEDE-------------- 122

Query: 219 SYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
                     E+++ D  EE E EEE+E+    GE  + + E++ EEE++
Sbjct: 123 ----------EDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE 162



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 32/122 (26%), Positives = 59/122 (48%), Gaps = 8/122 (6%)

Query: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG----- 183
           E+  E   E  ++I   D  D ED E  D E+E++E+ +E++EEEEE             
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGE--DVEDEEEEEEEEEEEEEEEENEDHQMNCHNTR 179

Query: 184 -YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 242
             ++ E+++   DE ++ DE  A S L  G+     +Y  + E +   +  + +E+  ++
Sbjct: 180 IMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDK 239

Query: 243 EE 244
            E
Sbjct: 240 NE 241



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%)

Query: 168 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 226
           +D + +E      P   + +    +E +D D  ED DE                  KEE 
Sbjct: 64  QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105

Query: 227 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
           + EE  +D  E G+E+EE+ E G R E+ + + ED+ ++ED
Sbjct: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 14/132 (10%)

Query: 149 DQEDNEAPDSEEEDDEDGD------------EDDEEEEENEAGPPEGYEEEEEEEEEEDE 196
           D  ++EA +SEEE +++G+            EDD+EEEE E    +  +   +    +D+
Sbjct: 3   DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62

Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD--EEDDDDYVEEGEEEEEEEEGGLRGEK 254
           DEDE E++ GS+ G+ E++VG     +    D  E+DD D +EE    + +     R  K
Sbjct: 63  DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122

Query: 255 RKRDAEDDGEEE 266
           +  D EDD EEE
Sbjct: 123 KMSDDEDDDEEE 134



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 14/112 (12%)

Query: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
           D  E + E+ +E+  +E E      + + EEE+++EEE+E+  +D+DE G+         
Sbjct: 3   DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGN--------- 53

Query: 217 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
                +K  I D++D+D+  E+   +  + E  +  +KRKR + DD  E+DD
Sbjct: 54  -----LKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 14/123 (11%)

Query: 148 FDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-- 204
           + +E++E     EE  +DG+ E+ +E  E    PPE  EE++EE + +D   D+D     
Sbjct: 135 YGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLK 194

Query: 205 -----------AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
                        + L E +E  G+ +   E  +  E D++  EE E E++E EG +R  
Sbjct: 195 KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVR 254

Query: 254 KRK 256
            +K
Sbjct: 255 PKK 257



 Score = 28.9 bits (63), Expect = 4.9
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 8/68 (11%)

Query: 188 EEEEEEEDEDEDEDEDEAGSELGEGE--------EEVGLSYLMKEEIQDEEDDDDYVEEG 239
           EE +EE + DE EDE++ G EL +          +  GL  L K+     E   + + + 
Sbjct: 494 EEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDS 553

Query: 240 EEEEEEEE 247
            +  E E+
Sbjct: 554 YQRHETEQ 561


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 36/95 (37%), Positives = 54/95 (56%)

Query: 172  EEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEED 231
            E+ E++   PE  EEEEEEEEEE+E+E+ +E+E G  + +  +        + EI  E++
Sbjct: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE 1400

Query: 232  DDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
            D   +++ EEEEEE+E     E    D EDD   E
Sbjct: 1401 DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHME 1435



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 30/92 (32%), Positives = 50/92 (54%)

Query: 154  EAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGE 213
            E  + EEE++E+ +E++ EEEE      +  +  + +E+EE E   E ED A  +  E E
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411

Query: 214  EEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
            EE        E+   +++DD ++E  E E+EE
Sbjct: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEE 1443



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 25/47 (53%), Positives = 36/47 (76%), Gaps = 7/47 (14%)

Query: 158  SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
            S+E  +E+ +E+DEEEEE E       EEEEE+EEEE+E+E+E+E+E
Sbjct: 1065 SKESSEEEEEEEDEEEEEEE-------EEEEEDEEEEEEEEEEEEEE 1104



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 25/51 (49%), Positives = 37/51 (72%), Gaps = 9/51 (17%)

Query: 157  DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
            +S EE++E+ DE++EEEEE         EEEE+EEEEE+E+E+E+E+   S
Sbjct: 1067 ESSEEEEEEEDEEEEEEEE---------EEEEDEEEEEEEEEEEEEENIQS 1108



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 63/115 (54%), Gaps = 21/115 (18%)

Query: 150  QEDNEAPDSEEEDDEDGDEDDEEEE--ENEAG-----PPEGYEEEEEEEEE--------- 193
            ++D   P+ EEE++E+ +E++EEEE  E E G      P+G + +E+EE E         
Sbjct: 1344 EDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSA 1403

Query: 194  ----EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244
                 +E+E+EDE+ + +E  + ++E   S++   E++ EE   +  +E  E +E
Sbjct: 1404 RLDDHEEEEEEDEEPSHNEDHDADDEDD-SHMESAEVEKEELPRESFKEVLENQE 1457



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 5/127 (3%)

Query: 147  GFDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEE----DEDEDED 201
            GF       P++  E DE    E+ +E  E +  P     EEE +E  E     E+   +
Sbjct: 1268 GFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRRE 1327

Query: 202  EDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAED 261
            E  A         E     L+K E ++EE++++  EE EEE EEEEGG   EK    A+ 
Sbjct: 1328 ETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKS 1387

Query: 262  DGEEEDD 268
              +EE +
Sbjct: 1388 QEKEEPE 1394



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 24/54 (44%), Positives = 33/54 (61%)

Query: 155  APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
            +P+S     E G   +  +E +E    E  EEEEEEEEEE+EDE+E+E+E   E
Sbjct: 1048 SPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE 1101



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 10/85 (11%)

Query: 146  DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
            DG   ++ E P+   E ++    DD EEEE         EE+EE    ED D D DED++
Sbjct: 1383 DGAKSQEKEEPEISTEKEDSARLDDHEEEE---------EEDEEPSHNEDHDAD-DEDDS 1432

Query: 206  GSELGEGEEEVGLSYLMKEEIQDEE 230
              E  E E+E       KE ++++E
Sbjct: 1433 HMESAEVEKEELPRESFKEVLENQE 1457



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 25/67 (37%), Positives = 36/67 (53%)

Query: 150  QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
            Q  N+   S E     G+     E   E+   E  EE+EEEEEEE+E+E+++E+E   E 
Sbjct: 1040 QSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099

Query: 210  GEGEEEV 216
             E EE +
Sbjct: 1100 EEEEENI 1106



 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 23/62 (37%)

Query: 186  EEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
            +E  EEEEE+EDE+E+E+E                       +EE++D+  EE EEEEEE
Sbjct: 1066 KESSEEEEEEEDEEEEEEE-----------------------EEEEEDEEEEEEEEEEEE 1102

Query: 246  EE 247
            EE
Sbjct: 1103 EE 1104



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 9/55 (16%)

Query: 141  QITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEED 195
            Q+  L     E+ E  + EEE++E+ +E+++EEEE         EEEEEEEEEE+
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE---------EEEEEEEEEEN 1105



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 11/118 (9%)

Query: 150  QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
            +E+ EA    E   E     ++EE+E  +      +   + + +       +      E 
Sbjct: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058

Query: 210  GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
            G+      L  L KE  ++EE+++D     EEEEEEEE     E+ + + E++ EEE+
Sbjct: 1059 GQ------LLELSKESSEEEEEEED-----EEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 14/34 (41%), Positives = 27/34 (79%), Gaps = 1/34 (2%)

Query: 149  DQEDNEAPDSEEEDDEDGDEDDEEEEEN-EAGPP 181
            ++E+ E  + EE+++E+ +E++EEEEEN ++ PP
Sbjct: 1078 EEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111



 Score = 35.8 bits (81), Expect = 0.040
 Identities = 14/46 (30%), Positives = 31/46 (67%)

Query: 132  RESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENE 177
            R  + EL ++ +  +  ++++ E  + EEE++++ +E++EEEEE E
Sbjct: 1058 RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103



 Score = 35.0 bits (79), Expect = 0.069
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 9/132 (6%)

Query: 122  NCEITNLEDYRESIFELLQ-QITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
            + E+   E  RES  E+L+ Q T+LD   Q  +  P+   +   D       E +  AG 
Sbjct: 1436 SAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGD 1495

Query: 181  PEGYEEEEEEE---EEEDEDEDEDEDEAGSELGEG-----EEEVGLSYLMKEEIQDEEDD 232
            PE   E +EE    E+  + + ++  E  +E  EG     E +      ++   Q+  + 
Sbjct: 1496 PEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQ 1555

Query: 233  DDYVEEGEEEEE 244
            DD  ++  E +E
Sbjct: 1556 DDTFQDCAETQE 1567



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 13/126 (10%)

Query: 151  EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL- 209
            +D+E  + EEED+E    +D + ++ +    E  E E+EE   E   E  +  E   +L 
Sbjct: 1406 DDHE--EEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLN 1463

Query: 210  ---GEGEEE------VGLSYLMKEEIQDEEDDDDYVEEGEEEEEE-EEGGLRGEKRKRDA 259
               G    E      V L+     E ++   D + V E +EE    E+   + +K  ++ 
Sbjct: 1464 VQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEV 1523

Query: 260  EDDGEE 265
            + + +E
Sbjct: 1524 DTEFKE 1529


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 25/139 (17%)

Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE-------------EEEEDE 196
           ++D+E    +EED    +EDDE  E+ E G   G  ++E+E             EEEE+E
Sbjct: 479 KDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEE 538

Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE---------EEEEEE 247
           D++E+E+E   E  E   EVG + L  +  ++EE++++ +EE E          +  EE 
Sbjct: 539 DKEEEEEEEDEERREERAEVG-APLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEA 597

Query: 248 GGLRGEKRKRDAEDDGEEE 266
           GG   E  +   ED G ++
Sbjct: 598 GGASSE--EESGEDTGPQD 614



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 40/173 (23%), Positives = 74/173 (42%), Gaps = 52/173 (30%)

Query: 147 GFDQEDNEAPDSEEEDDED-----------------GDEDDEE--EEENEAGPPEGYEEE 187
           G D ED+E  + EEE++E+                 G E+DE+  +  +  GP   ++  
Sbjct: 184 GHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGH 243

Query: 188 EEEEEEEDEDEDEDED-------------------EAGSELGEGEEEVGLSYLMKEEIQD 228
           EE+++++D+D+D+D+D                   E   ++ +G      S+  +   +D
Sbjct: 244 EEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEED 303

Query: 229 EEDDDDYVEE-------GEEEEEEEEGGLRGE-------KRKRDAEDDGEEED 267
           + DDDD   E        ++  +EE   + GE        R +   D+ E+ED
Sbjct: 304 DNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDED 356



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 21/121 (17%)

Query: 146 DGFDQEDNE-----APDSEEEDDEDGDEDDEEEEEN------EAGPPEGYEEEEEEEEEE 194
           D  D+ED E     + + EEE++ED +E++EEE+E       E G P   +  EEEEEEE
Sbjct: 515 DQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEE 574

Query: 195 DEDEDEDEDE---AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLR 251
            E  +EDE       + L   EE  G S       ++E  +D   ++ +E    + G L 
Sbjct: 575 -EGLEEDEPRFTIIPNPLDRREEAGGAS------SEEESGEDTGPQDAQEYGNYQPGSLC 627

Query: 252 G 252
           G
Sbjct: 628 G 628



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 21/128 (16%)

Query: 158 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED-------------- 203
           S +++DED     E           G++ E++E EEE+E+E+E+E+              
Sbjct: 159 SHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRG 218

Query: 204 ---EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE 260
              E   ++ +G    G S+  +   +D++DDDD     ++++++++  +    +    +
Sbjct: 219 HGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDD----DDDDDDDDDVSIEYRHQAHRHQ 274

Query: 261 DDGEEEDD 268
             G EED+
Sbjct: 275 GHGIEEDE 282



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 28/148 (18%)

Query: 149 DQEDNEAPDSEE------------EDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDE 196
           D++++E   SE             + ++D  E++EEEEE E      Y  +         
Sbjct: 162 DEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGS 221

Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDD-------------YVEEGEEEE 243
           +EDED  +     G      G      ++  D++DDDD             +   G EE+
Sbjct: 222 EEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEED 281

Query: 244 EEEEGGLR---GEKRKRDAEDDGEEEDD 268
           E+   G        R R  E+D  ++DD
Sbjct: 282 EDVSDGHHHRDPSHRHRSHEEDDNDDDD 309



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 42/175 (24%), Positives = 73/175 (41%), Gaps = 66/175 (37%)

Query: 159 EEEDDEDGDED--------------DEEEEENE----------AGPPEGYEEEEEEEEEE 194
           +EE+DED   +              DEEEEE E          +  P G++ +EE+ ++E
Sbjct: 350 DEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDE 409

Query: 195 DEDE----------DEDEDEAGSELGEG---------EEEVG------------------ 217
            + E           E+++E  +ELG           +EE G                  
Sbjct: 410 YKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHT 469

Query: 218 ----LSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKR-KRDAEDDGEEED 267
                S+L K++ ++E++ ++     EE++E  E G +G     RD ED+ +EE+
Sbjct: 470 VVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEE 524



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 41/139 (29%)

Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE-----------EEEEEDEDE 198
           +ED++  D +++DD+D D   E   +       G EE+E+                 E++
Sbjct: 244 EEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEED 303

Query: 199 DEDEDEAGSELG-----------------EGEEEVGLSYLMKEEIQDEEDDDD------- 234
           D D+D+  +E G                  GE    +     +  +DEE+D+D       
Sbjct: 304 DNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWH 363

Query: 235 ----YVEEG--EEEEEEEE 247
               +V  G  +EEEEEEE
Sbjct: 364 QGPQHVHHGLVDEEEEEEE 382



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 26/107 (24%)

Query: 156 PDSEEEDDEDGDEDDEEEE--ENEAGPPEGYEEEEEEEEEEDED-------------EDE 200
           P    +D + GDE    EE      G   G+     E+ E+  +             +DE
Sbjct: 104 PGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDE 163

Query: 201 DEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
           DEDE  S            ++++   +  + +DD   EGEE EEEEE
Sbjct: 164 DEDEVVSSEHH-------HHILRHGHRGHDGEDD---EGEE-EEEEE 199


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 44/140 (31%), Positives = 78/140 (55%), Gaps = 13/140 (9%)

Query: 137 ELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDE 196
           E ++  T   G  +E   A    EE+D+  DE+D+ EE+ EAG     +E+++E+ EED 
Sbjct: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG-----KEDKDEKGEEDG 157

Query: 197 DEDEDEDEAGSELGE------GEEEVGLSYLMKEEIQDEEDDDDYVE--EGEEEEEEEEG 248
            ED++ +E G +  E      GE+  G     KE+ +DE++++D  E  +G+E E+ +E 
Sbjct: 158 KEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEK 217

Query: 249 GLRGEKRKRDAEDDGEEEDD 268
           G + E +    ++D +E +D
Sbjct: 218 GDKKEGKDVKVKEDEKERED 237



 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 25/150 (16%)

Query: 127 NLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEE 186
           N+ED  E             G  +E   A    EE+D+  DE+D+ EE+ EAG     +E
Sbjct: 104 NIEDATEK-----------GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG-----KE 147

Query: 187 EEEEEEEEDEDEDEDEDEAGSELGE------GEEEVGLSYLMKEEIQDEEDDDDYVEEG- 239
           +++E+ EED  ED++ +E G +  E      GE+  G     KE+ +DE++++D  E G 
Sbjct: 148 DKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207

Query: 240 --EEEEEEEEGGLRGEKRKRDAEDDGEEED 267
             E E+ +E+G  +  K  +  ED+ E ED
Sbjct: 208 GKENEDGKEKGDKKEGKDVKVKEDEKERED 237



 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 49/143 (34%), Positives = 76/143 (53%), Gaps = 28/143 (19%)

Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED-------- 197
           D  DQ + +    +E+ DE G+ED +E++    G  +G + +E+E+ ++ ED        
Sbjct: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKN---GNEKGEDAKEKEDGKKGEDGKGNGEDG 189

Query: 198 ----EDEDEDEAGSELGEGEE-EVGLSYLMKEEIQDEEDDDDYVEEGEEEEE---EEEGG 249
               EDE E+E   E G+G+E E G     KE+   +E  D  V+E E+E E   E+EGG
Sbjct: 190 KEKGEDEKEEEDRKETGDGKENEDG-----KEKGDKKEGKDVKVKEDEKEREDGKEDEGG 244

Query: 250 LRGE--KRKRD--AEDDGEEEDD 268
              E  K K D   E++G+EED+
Sbjct: 245 NEEEAGKEKEDLKEEEEGKEEDE 267



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 23/145 (15%)

Query: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
           EDY E+      +IT     ++E  E    +EE+ ED  E   E++E  A      + EE
Sbjct: 74  EDYNENAKNGEAKITEAPASEKEIVEV---KEENIEDATEKGGEKKEAVAAE---VKNEE 127

Query: 189 EEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG 248
           E+++E++ED++E++ EAG E  + + E           +D ++D +  E+GE+ +E+E+G
Sbjct: 128 EDQKEDEEDQNEEKGEAGKEDKDEKGE-----------EDGKEDKNGNEKGEDAKEKEDG 176

Query: 249 GL------RGEKRKRDAEDDGEEED 267
                    GE  K   ED+ EEED
Sbjct: 177 KKGEDGKGNGEDGKEKGEDEKEEED 201



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 36/109 (33%), Positives = 65/109 (59%), Gaps = 13/109 (11%)

Query: 146 DGFDQEDNEA--PDSEEEDDEDGDEDDEEE----EENEAGPPEGYEEEEEE---EEEEDE 196
           DG   ED +    D +E+ +++ +E+D +E    +ENE G  +G ++E ++   +E+E E
Sbjct: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKE 234

Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
            ED  EDE G+E   G+E+  L    KEE + +E+D+   ++G++EE +
Sbjct: 235 REDGKEDEGGNEEEAGKEKEDL----KEEEEGKEEDEIKEDDGKKEEPQ 279



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 36/114 (31%), Positives = 65/114 (57%), Gaps = 15/114 (13%)

Query: 146 DGFDQEDNEAPDSEEEDDEDGDE--DDEEEEENEAGPPEGYEEEEEEEEEEDED------ 197
           D  ++ED +  +  + + EDG E  +DE+EEE+     +G E E+ +E+ + ++      
Sbjct: 169 DAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKV 228

Query: 198 -EDEDEDEAGSE-LGEGEEEVGLSYLMKEEIQDEED--DDDYVEEGEEEEEEEE 247
            EDE E E G E  G  EEE G     KE++++EE+  ++D ++E + ++EE +
Sbjct: 229 KEDEKEREDGKEDEGGNEEEAGKE---KEDLKEEEEGKEEDEIKEDDGKKEEPQ 279



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 30/103 (29%), Positives = 56/103 (54%), Gaps = 4/103 (3%)

Query: 170 DEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE 229
           +E+  EN         E    E+E  E ++E+ ++A  + GE +E V      +EE Q E
Sbjct: 73  EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132

Query: 230 EDDDDYVEEGE--EEEEEEEGGLRGEKRKRDAE--DDGEEEDD 268
           +++D   E+GE  +E+++E+G   G++ K   E  +D +E++D
Sbjct: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 12/109 (11%)

Query: 158 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVG 217
           +E + +   +ED  E  +N           E+E  E  E+  ED  E G     GE++  
Sbjct: 64  AETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKG-----GEKKEA 118

Query: 218 LSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
           ++  +K E +D+++D       EE++ EE+G    E +    E+DG+E+
Sbjct: 119 VAAEVKNEEEDQKED-------EEDQNEEKGEAGKEDKDEKGEEDGKED 160



 Score = 36.2 bits (82), Expect = 0.031
 Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)

Query: 159 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEE-EEEEEDEDEDEDEDEAGS 207
           +E++ EDG ED+   EE      E  +EEEE +EE+E +++D  ++E  S
Sbjct: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)

Query: 131 YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 190
           Y+E I    + +T L G + + +      + + E+ DE+DE++E+          E+EEE
Sbjct: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 657

Query: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
           E++E+ D  ED  ++     E E E G      E  +D+ED+DD  ++ E+E+ E EG  
Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 712

Query: 251 RGEKRKRDAED 261
                  D+ D
Sbjct: 713 SSSSSSGDSSD 723



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 240
           E  E++EE+E++EDEDE+E++DE G    +G +    S   + E  DE E+DD+  ++ E
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
           +++E+E+    G      +  D  + D
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 188 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 241
           + + E E++DE+      EDE+E   E G+  E+ G S         E   +D  E+G+E
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 686

Query: 242 EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
            EE++E        + D EDD E+ED+
Sbjct: 687 NEEDDED-------EDDDEDDDEDEDN 706



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 197
           D+ ++   + E+++DED DEDD+E+E+NE+           +  + D +
Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 35.0 bits (79), Expect = 0.069
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 152 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
           ++E+ D +E +++D DEDD+E+++         E+E+ E E          D + S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 725


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)

Query: 131 YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 190
           Y+E I    + +T L G + + +      + + E+ DE+DE++E+          E+EEE
Sbjct: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 657

Query: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
           E++E+ D  ED  ++     E E E G      E  +D+ED+DD  ++ E+E+ E EG  
Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 712

Query: 251 RGEKRKRDAED 261
                  D+ D
Sbjct: 713 SSSSSSGDSSD 723



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 240
           E  E++EE+E++EDEDE+E++DE G    +G +    S   + E  DE E+DD+  ++ E
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
           +++E+E+    G      +  D  + D
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 188 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 241
           + + E E++DE+      EDE+E   E G+  E+ G S         E   +D  E+G+E
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 686

Query: 242 EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
            EE++E        + D EDD E+ED+
Sbjct: 687 NEEDDED-------EDDDEDDDEDEDN 706



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 197
           D+ ++   + E+++DED DEDD+E+E+NE+           +  + D +
Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 35.0 bits (79), Expect = 0.069
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 152 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
           ++E+ D +E +++D DEDD+E+++         E+E+ E E          D + S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 725


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)

Query: 131 YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 190
           Y+E I    + +T L G + + +      + + E+ DE+DE++E+          E+EEE
Sbjct: 645 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 694

Query: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
           E++E+ D  ED  ++     E E E G      E  +D+ED+DD  ++ E+E+ E EG  
Sbjct: 695 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 749

Query: 251 RGEKRKRDAED 261
                  D+ D
Sbjct: 750 SSSSSSGDSSD 760



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 240
           E  E++EE+E++EDEDE+E++DE G    +G +    S   + E  DE E+DD+  ++ E
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735

Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
           +++E+E+    G      +  D  + D
Sbjct: 736 DDDEDEDNESEGSSSSSSSSGDSSDSD 762



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 188 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 241
           + + E E++DE+      EDE+E   E G+  E+ G S         E   +D  E+G+E
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 723

Query: 242 EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
            EE++E        + D EDD E+ED+
Sbjct: 724 NEEDDED-------EDDDEDDDEDEDN 743



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 197
           D+ ++   + E+++DED DEDD+E+E+NE+           +  + D +
Sbjct: 716 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 35.0 bits (79), Expect = 0.069
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 152 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
           ++E+ D +E +++D DEDD+E+++         E+E+ E E          D + S+
Sbjct: 715 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 762


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 36/125 (28%), Positives = 74/125 (59%), Gaps = 2/125 (1%)

Query: 124  EITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEE-DDEDGDEDDEEEEENEAGPPE 182
            E+ + E + E +  LL ++   +    E+ E  + EEE ++E+  E++EE +E E G  +
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK 2278

Query: 183  GYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 242
              E+EEEE++++ +++ ++E +   E+ E +EE+ +S    E + DEE++++     EE 
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI-MSEEETESLSDEEEEEESCSLEEEV 2337

Query: 243  EEEEE 247
            + E+E
Sbjct: 2338 DREKE 2342



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 11/146 (7%)

Query: 132  RESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEE 191
            +E     + ++   + F +E     D  E+ +    E++EE EE E    E   EEEEE 
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269

Query: 192  EEEDEDED-----EDEDEAGSELGEGEEEVGLS---YLMKEEIQDEEDDDDYVEEGEEEE 243
            +EE+E E+     E+E++   +  + +EEV      +  KEEI  EE+ +   +E EEEE
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329

Query: 244  E---EEEGGLRGEKRKRDAEDDGEEE 266
                EEE     E  K++ +   +E+
Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKLQEQ 2355



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 37/142 (26%), Positives = 75/142 (52%), Gaps = 14/142 (9%)

Query: 128  LEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDE-EEEENEAGPPEGYEE 186
            L+D  E   E  + I +L    ++  EA   ++  ++   + DE E EE+ +   E   +
Sbjct: 2176 LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLD 2235

Query: 187  EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 246
            E E++E    +E+E+ +E      E E E       +EE+++EE++    EEGEE++ E+
Sbjct: 2236 ELEKQESLSSEEEEEREE------EEERE-------EEEVREEEEERKEEEEGEEKQVEK 2282

Query: 247  EGGLRGEKRKRDAEDDGEEEDD 268
            E   + +K+K   +++ +E+++
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEE 2304



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 29/128 (22%)

Query: 158  SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE-------------DEDE 204
            S+E+  +D +E   EEE +     EG E+E++  EE+   ++E             ++  
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSR----EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588

Query: 205  AGSELGEGEEEVGLSYLMKEEIQDE-----------EDDDDYVE-EGEEEEEEEEGGLRG 252
            A  E    +EE  L+   ++  Q+E           +DD +  + EG+  ++EE    RG
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRG 1648

Query: 253  EKRKRDAE 260
            EK  ++AE
Sbjct: 1649 EKLSQEAE 1656



 Score = 32.0 bits (71), Expect = 0.58
 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 7/102 (6%)

Query: 150  QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-GYEEEEEEEEE----EDEDEDEDEDE 204
            Q+  E P  E+  D    E  +E EE E    E  ++EEE  +EE    E++ +  +E+E
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754

Query: 205  AGSELGE--GEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244
            A +   E   EEE  L+   +  IQ++E    + E+  EEEE
Sbjct: 1755 ALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796



 Score = 29.3 bits (64), Expect = 3.8
 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 4/101 (3%)

Query: 171  EEEEENEAGPPEGYEEEEEEEEEE---DEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQ 227
            EEE+ ++AG     EEE  +E+++   +E +   E+   S+  E + +      ++EE+ 
Sbjct: 1492 EEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVS 1551

Query: 228  DE-EDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
             E E+ +  V E +   +EE    R  +++  AE    +E+
Sbjct: 1552 REGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 48/147 (32%), Positives = 69/147 (46%), Gaps = 19/147 (12%)

Query: 129  EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
            ED +ES+ E  +        ++E+    + EEEDD+D D DD +E EN+       E  E
Sbjct: 1035 EDEKESLSEEQEST------EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088

Query: 189  EEEEEEDEDE------DEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 242
            ++E + DE+E       + E  + SE  E  E    S   +      ED+++ V   EEE
Sbjct: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSS---ESSPSSSEDEEEVVAREEEE 1145

Query: 243  EEEEEGGLRGEKR----KRDAEDDGEE 265
            EEEEE  +  E        D E DGEE
Sbjct: 1146 EEEEEEMVAEESMASAGPEDFEQDGEE 1172



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 5/115 (4%)

Query: 152  DNEAPDSEEEDDED-GDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 210
            D E  +SE E D D  D   E  + +  G   G         E D   +EDE E+ SE  
Sbjct: 988  DEEDEESERERDRDMADTPCELAKRDPKGV--GVRRRPARPLELDSGGEEDEKESLSEEQ 1045

Query: 211  EGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
            E  EE       +EE ++++DDDD  +  E E ++E+  L     K + + D EE
Sbjct: 1046 ESTEEE--EEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 36/119 (30%)

Query: 181  PEGYEEEEEEEEEEDEDED---------------------------------EDEDEAGS 207
            P    +EE+EE E + D D                                 EDE E+ S
Sbjct: 983  PSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLS 1042

Query: 208  ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
            E  E  EE       +EE ++E+DDDD  ++ +E E ++E     E  ++D  D  EEE
Sbjct: 1043 EEQESTEE---EEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 6/87 (6%)

Query: 187  EEEEEEEEDEDEDEDEDEAGSELGEGEEE-VGLSYLMKEEIQ----DEEDDDDYVEEGEE 241
            +EE+EE E E  D D  +   EL + + + VG+       ++     EED+ + + E +E
Sbjct: 988  DEEDEESERE-RDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQE 1046

Query: 242  EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
              EEEE     E+ + D +DD ++ D+
Sbjct: 1047 STEEEEEAEEEEEEEDDDDDDSDDRDE 1073



 Score = 34.7 bits (78), Expect = 0.090
 Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 72/174 (41%)

Query: 149  DQEDNEAPDSEEEDDED-----------GDEDDEE-----------------------EE 174
            D +D++  D  E DDED           GD D+EE                       E 
Sbjct: 1064 DDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFES 1123

Query: 175  ENEAGPPEGY--------EEEEEEEEEE-----------DEDEDEDEDEAGSELGEGEEE 215
             +E+ P            EEEEEEEEEE            ED ++D +EA   L  G   
Sbjct: 1124 SSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAA--LAPGAPA 1181

Query: 216  VGLSYLMKEEIQDEED-----------DDDYVEEGEEE-----EEEEEGGLRGE 253
            V  S  M+EE+  E +           D+  +  G EE     E  EE GL  E
Sbjct: 1182 VD-SLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQE 1234


>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
          Length = 466

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 57/239 (23%), Positives = 115/239 (48%), Gaps = 4/239 (1%)

Query: 12  RNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLEL 71
           RN    +     L+       EIE L    K    L +  ++ + + ++ +++KL+KLE 
Sbjct: 11  RNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEY 70

Query: 72  SDNIISGGLEVLA--EKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLE 129
             N+    +E +   E C  L  L+L+ N I +LS+++ LQ+  +LK L L      + +
Sbjct: 71  L-NLALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFD 129

Query: 130 DYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 189
            YRE +   L Q+ +LDG + E +E   + ++      +  E+E+++     +  EE + 
Sbjct: 130 HYREFVVATLPQLKWLDGKEIEPSERIKALQDYSVIEPQIREQEKDHCLKRAKLKEEAQR 189

Query: 190 EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYL-MKEEIQDEEDDDDYVEEGEEEEEEEE 247
           + +EED++ED+  +         +    LS L  K+ +Q  + ++   ++ +  E++ E
Sbjct: 190 KHQEEDKNEDKRSNAGFDGRWYTDINATLSSLESKDHLQAPDTEEHNTKKLDNSEDDLE 248


>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
          Length = 406

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 12/118 (10%)

Query: 132 RESIFELLQQITYLDGFDQEDNE--APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 189
           +E+++  +Q  +     + E+N+  AP   EE++E  ++D+EE ++      E  EEEEE
Sbjct: 247 QETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEE 306

Query: 190 --EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
             +EEEE EDE+E+E E    + EGEEE     L +EE+++EE   + +EE E+  EE
Sbjct: 307 VEDEEEEVEDEEEEEVEEAEYVEEGEEE-----LEEEELEEEE---EVLEENEQRGEE 356



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 1/90 (1%)

Query: 148 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDEDEAG 206
           +DQE  +A ++ EE++E  DE++E E+E E    E  Y EE EEE EE+E E+E+E    
Sbjct: 290 YDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349

Query: 207 SELGEGEEEVGLSYLMKEEIQDEEDDDDYV 236
           +E    E  + L   +   ++ EE  ++++
Sbjct: 350 NEQRGEEFHLPLEMPLSIFVEAEEKRENFI 379



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)

Query: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
           E+Y + + +  +     +  + E+ E  D EEE+ E+ +  +E EEE         EEEE
Sbjct: 288 EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE--------LEEEE 339

Query: 189 EEEEEEDEDEDEDEDE 204
            EEEEE  +E+E   E
Sbjct: 340 LEEEEEVLEENEQRGE 355


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)

Query: 149 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 204
           D ED+    SEEED E   DG+E + +EE   A   E  EE E+EEEEEE+E+ DE+E+E
Sbjct: 3   DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 205 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
              +    +   G   L + ++ DE +D+D  E+G E+  E+E
Sbjct: 61  EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)

Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 205
           E  E P+ EEE++E+ + D+EEEEE++  PP+     G+  +E + ++E EDED+ ED  
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 262
                 G E++    L KEEI+    D+  +      +E+  G  R +   RD  ++
Sbjct: 95  ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)

Query: 184 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 243
           + EEE+ E   D +E E ++E  S  G  +E         EE +DEE++++  EE  +EE
Sbjct: 9   FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57

Query: 244 EEEEGGLRGEKRKR---------DAEDDGEEED 267
           EEEE   R  K+ R         D +D+ E+ED
Sbjct: 58  EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 229 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 268
           EE+D +   +GEE E +EE     G +++ + ED+ EEE++
Sbjct: 11  EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)

Query: 194 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
           + ED +  E+E      +GEE              E D++     G E+EEE E     E
Sbjct: 3   DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49

Query: 254 KRKRDAEDDGEEEDD 268
           + +   E++ EE+DD
Sbjct: 50  EEEEYDEEEEEEDDD 64


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)

Query: 149 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 204
           D ED+    SEEED E   DG+E + +EE   A   E  EE E+EEEEEE+E+ DE+E+E
Sbjct: 3   DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 205 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
              +    +   G   L + ++ DE +D+D  E+G E+  E+E
Sbjct: 61  EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)

Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 205
           E  E P+ EEE++E+ + D+EEEEE++  PP+     G+  +E + ++E EDED+ ED  
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 262
                 G E++    L KEEI+    D+  +      +E+  G  R +   RD  ++
Sbjct: 95  ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)

Query: 184 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 243
           + EEE+ E   D +E E ++E  S  G  +E         EE +DEE++++  EE  +EE
Sbjct: 9   FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57

Query: 244 EEEEGGLRGEKRKR---------DAEDDGEEED 267
           EEEE   R  K+ R         D +D+ E+ED
Sbjct: 58  EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 229 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 268
           EE+D +   +GEE E +EE     G +++ + ED+ EEE++
Sbjct: 11  EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)

Query: 194 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
           + ED +  E+E      +GEE              E D++     G E+EEE E     E
Sbjct: 3   DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49

Query: 254 KRKRDAEDDGEEEDD 268
           + +   E++ EE+DD
Sbjct: 50  EEEEYDEEEEEEDDD 64


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)

Query: 149 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 204
           D ED+    SEEED E   DG+E + +EE   A   E  EE E+EEEEEE+E+ DE+E+E
Sbjct: 3   DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 205 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
              +    +   G   L + ++ DE +D+D  E+G E+  E+E
Sbjct: 61  EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)

Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 205
           E  E P+ EEE++E+ + D+EEEEE++  PP+     G+  +E + ++E EDED+ ED  
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 262
                 G E++    L KEEI+    D+  +      +E+  G  R +   RD  ++
Sbjct: 95  ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)

Query: 184 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 243
           + EEE+ E   D +E E ++E  S  G  +E         EE +DEE++++  EE  +EE
Sbjct: 9   FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57

Query: 244 EEEEGGLRGEKRKR---------DAEDDGEEED 267
           EEEE   R  K+ R         D +D+ E+ED
Sbjct: 58  EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 229 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 268
           EE+D +   +GEE E +EE     G +++ + ED+ EEE++
Sbjct: 11  EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)

Query: 194 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
           + ED +  E+E      +GEE              E D++     G E+EEE E     E
Sbjct: 3   DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49

Query: 254 KRKRDAEDDGEEEDD 268
           + +   E++ EE+DD
Sbjct: 50  EEEEYDEEEEEEDDD 64


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.301    0.130    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,480,559
Number of Sequences: 37866
Number of extensions: 835467
Number of successful extensions: 67601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1408
Number of HSP's successfully gapped in prelim test: 724
Number of HSP's that attempted gapping in prelim test: 8712
Number of HSP's gapped (non-prelim): 21067
length of query: 268
length of database: 18,247,518
effective HSP length: 100
effective length of query: 168
effective length of database: 14,460,918
effective search space: 2429434224
effective search space used: 2429434224
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press