Search of human proteins with 13489083

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13489083 SAPS domain family, member 3 [Homo sapiens]
         (793 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13489083 SAPS domain family, member 3 [Homo sapiens]              1585   0.0  
gi|37537701 SAPS domain family, member 2 [Homo sapiens]               700   0.0  
gi|151101459 SAPS domain family, member 1 [Homo sapiens]              633   0.0  
gi|169218088 PREDICTED: similar to SAPS domain family, member 2 ...    76   1e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    54   7e-07
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    50   6e-06
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    50   6e-06
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    50   6e-06
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    49   1e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    49   1e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    45   2e-04
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ...    45   3e-04
gi|210032580 SET domain containing 1B [Homo sapiens]                   44   8e-04
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                  43   0.001
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    42   0.002
gi|37595553 ring finger protein 111 [Homo sapiens]                     42   0.002
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    42   0.003
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    42   0.003
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    42   0.003
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    42   0.003
gi|147903302 MAP7 domain containing 3 [Homo sapiens]                   41   0.004

>gi|13489083 SAPS domain family, member 3 [Homo sapiens]
          Length = 793

 Score = 1585 bits (4104), Expect = 0.0
 Identities = 793/793 (100%), Positives = 793/793 (100%)

Query: 1   MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 60
           MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF
Sbjct: 1   MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 60

Query: 61  IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 120
           IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL
Sbjct: 61  IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 120

Query: 121 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 180
           ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ
Sbjct: 121 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 180

Query: 181 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 240
           DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA
Sbjct: 181 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 240

Query: 241 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 300
           TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS
Sbjct: 241 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 300

Query: 301 VNKSVLEAIRGRLGSFHELLLEPPKNMFFKYTWNNFLHTQVEICIALILASPFENTENAT 360
           VNKSVLEAIRGRLGSFHELLLEPPKNMFFKYTWNNFLHTQVEICIALILASPFENTENAT
Sbjct: 301 VNKSVLEAIRGRLGSFHELLLEPPKNMFFKYTWNNFLHTQVEICIALILASPFENTENAT 360

Query: 361 ITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHS 420
           ITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHS
Sbjct: 361 ITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHS 420

Query: 421 TDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLAFSDYQMQQMTSNFID 480
           TDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLAFSDYQMQQMTSNFID
Sbjct: 421 TDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLAFSDYQMQQMTSNFID 480

Query: 481 QFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEE 540
           QFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEE
Sbjct: 481 QFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEE 540

Query: 541 DIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEP 600
           DIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEP
Sbjct: 541 DIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEP 600

Query: 601 PNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNS 660
           PNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNS
Sbjct: 601 PNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNS 660

Query: 661 PVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKE 720
           PVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKE
Sbjct: 661 PVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKE 720

Query: 721 TLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQ 780
           TLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQ
Sbjct: 721 TLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQ 780

Query: 781 PSAPGDTSVNGPV 793
           PSAPGDTSVNGPV
Sbjct: 781 PSAPGDTSVNGPV 793


>gi|37537701 SAPS domain family, member 2 [Homo sapiens]
          Length = 932

 Score =  700 bits (1806), Expect = 0.0
 Identities = 396/875 (45%), Positives = 525/875 (60%), Gaps = 112/875 (12%)

Query: 1   MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 60
           MFWKFDL+++SH+D LL++E VTL+ELMDE+D+LQECKAQN+KL++FL + +C+E+LVS 
Sbjct: 1   MFWKFDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVSL 60

Query: 61  IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 120
           I ++PP DM+EK+R+KYPN +CELLT DV Q++DRLG DESLL  LY FL ++ PLNPLL
Sbjct: 61  ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDRLGGDESLLSLLYDFLDHEPPLNPLL 120

Query: 121 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 180
           ASFFSK +  LI+RK EQ++ FLKKK  F+ L++KHIGTSA+MDLLLRL++C+EP   RQ
Sbjct: 121 ASFFSKTIGNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAGLRQ 180

Query: 181 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 240
           DVL+WLNEEK+IQRLVE++HPSQ+EDR SNASQ+LC+IVRL RDQ  Q+Q + EPDPLL 
Sbjct: 181 DVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEALEPDPLLT 240

Query: 241 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 300
            LE Q+ +EQLL N+F  ++ ES +VS  Q+LLTLLETRR   EG ++    G+  S  +
Sbjct: 241 ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVGTEGLVDSFSQGLERS-YA 299

Query: 301 VNKSVLEAIRGRLGSFHELLLEPPK----------------------------------- 325
           V+ SVL  I  RL  FH+LLL PPK                                   
Sbjct: 300 VSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTP 359

Query: 326 ----------------NMFFKYTWNNFLHTQVEICIALILA------------------S 351
                           ++FFKYTWNNFLH QVE+CIA IL+                   
Sbjct: 360 SINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHAAREERTEASGSESRVEP 419

Query: 352 PFENTENATITDQD--STGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGH 409
           P EN   +  T Q   S  DN ++ HLFQKC L++RILEAWE N+  QA GG R G MGH
Sbjct: 420 PHENGNRSLETPQPAASLPDNTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGH 479

Query: 410 LTRIANCIVHSTDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLAFSDY 469
           LTRIAN +V + ++GP    + ++I+ LP + R RWE+F   +L ETN+RNTVDLAFSDY
Sbjct: 480 LTRIANAVVQNLERGPVQTHISEVIRGLPADCRGRWESFVEETLTETNRRNTVDLAFSDY 539

Query: 470 QMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNE-SGNIALFEACCKER 528
           Q+QQMT+NF+DQFGFNDE+FADQDD  N  FDR+++INF ++ +E S + ALFEACC +R
Sbjct: 540 QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADEDSPSAALFEACCSDR 599

Query: 529 IQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD-------- 580
           IQ FDD   ++EDIWE+           R   G+  + ES      +   QD        
Sbjct: 600 IQPFDD--DEDEDIWEDSDTRCAARVMARPRFGAPHASESCSKNGPERGGQDGKASLEAH 657

Query: 581 ------LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAP--LDSVGSDVWSTEEP 632
                    P+    E       SE   W+A FD P  +T  AP  +  VGS VW+    
Sbjct: 658 RDAPGAGAPPAPGKKEAPPVEGDSEGAMWTAVFDEPANSTPTAPGVVRDVGSSVWAAGTS 717

Query: 633 MPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETS----------TEPMDPLTPSAAALA 682
            P +E GWA F++F     ++   R +SPV+ E S           +   P +P A  + 
Sbjct: 718 AP-EEKGWAKFTDFQPFCCSESGPRCSSPVDTECSHAEGSRSQGPEKAFSPASPCAWNVC 776

Query: 683 VQPEAAGSVAMEASSDGEEDAESTDK----VTETVMNGGMKETLSLTVDAKTETAVFKSE 738
           V  +A   +A ++SS G   +E  D+      + V  G  +E   L   A+TE AV    
Sbjct: 777 VTRKAP-LLASDSSSSGGSHSEDGDQKAASAMDAVSRGPGREAPPLPTVARTEEAV---- 831

Query: 739 EGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            G++  +       A   P+   A  A   PP ++
Sbjct: 832 -GRVGCADSRLLSPACPAPKEVTAAPAVAVPPEAT 865


>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
          Length = 881

 Score =  633 bits (1633), Expect = 0.0
 Identities = 381/914 (41%), Positives = 516/914 (56%), Gaps = 161/914 (17%)

Query: 1   MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 60
           MFWKFDLH+SSH+DTLLERED++L EL+DEEDVLQECK  NRKL++FLL+   L+ +V++
Sbjct: 1   MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAW 60

Query: 61  IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 120
           + +EPP   +E++RYKYP+++CE+LTSDV Q+ND LG DESLL +LY FL +   LNPLL
Sbjct: 61  VTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLL 120

Query: 121 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 180
           ASFFSKV+ ILI+RK +Q+V FL+KK DFVDL+++HIGTSAIMDLLLRLLTC+E PQ RQ
Sbjct: 121 ASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQ 180

Query: 181 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 240
           DV+NWLNEEKI+QRL+E +HPS++E++HSNASQSLC+I+RLSR+QM+Q+Q+S EPD LLA
Sbjct: 181 DVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLA 240

Query: 241 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRP------------TFEGHIE 288
           TLEKQE IEQLLSN+F  E+++S IVS IQ+LLTLLE RRP            + +G +E
Sbjct: 241 TLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLE 300

Query: 289 ICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPK----------------------- 325
           +   G   S  S +   L A+R RL  FH+LLLEPPK                       
Sbjct: 301 LLAQGALESTVS-SVGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVV 359

Query: 326 ----------------------------NMFFKYTWNNFLHTQVEICIA--LILASPFEN 355
                                       ++FF Y +NNFLH QVE C++  L L  P ++
Sbjct: 360 KLLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPPDS 419

Query: 356 TENATITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIAN 415
           +    I        N ++KHL Q+C+L+ERIL +WE N++ Q  GG R GYMGHLTR+A 
Sbjct: 420 SPETPI-------QNPVVKHLLQQCRLVERILTSWEENDRVQCAGGPRKGYMGHLTRVAG 472

Query: 416 CIVHSTDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDL----------- 464
            +V +T+KGPN+  ++QL+K+LP E +E+WE F +  L ETNK+N VDL           
Sbjct: 473 ALVQNTEKGPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSD 532

Query: 465 -------------------AFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSD 505
                              AF D+QMQ+MTS FID FGFNDE+F +Q++  N  FD+ ++
Sbjct: 533 DEDDRLKEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTAN 592

Query: 506 INFTLNT-NESGNIALFEACCKERIQQFDD-------------GGSDEED-IWEEKHIA- 549
           I F+LN  +E+ N  L E C K+RIQQFDD             G SD ED  W+   +A 
Sbjct: 593 ITFSLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLAR 652

Query: 550 ----FTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEP----P 601
                 P   R  S GSTDSE+  + +EE+   ++    ++      +      P    P
Sbjct: 653 GARLGQPPGVR--SGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGP 710

Query: 602 NWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSP 661
           +W+A FD         P D+  S   S EE + T              L T+    ++ P
Sbjct: 711 SWTATFD-------PVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQS--LASPP 761

Query: 662 VEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKET 721
                     DP  PSA               + +++G +  E +      V  G ++ T
Sbjct: 762 ARDALQLRSQDPTPPSAP--------------QEATEGSKVTEPSAPCQALVSIGDLQAT 807

Query: 722 LSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRP---PSSSPEQRT 778
                     +A   S+      S       A + P+T E +  +P P   P S   Q  
Sbjct: 808 FH-----GIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGE-KSPEPLGLPQSQSAQAL 861

Query: 779 GQPSAPGDTSVNGP 792
             P  P  ++  GP
Sbjct: 862 TPPPIPNGSAPEGP 875


>gi|169218088 PREDICTED: similar to SAPS domain family, member 2
           [Homo sapiens]
          Length = 79

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 33/44 (75%), Positives = 41/44 (93%)

Query: 163 MDLLLRLLTCIEPPQPRQDVLNWLNEEKIIQRLVEIVHPSQEED 206
           MDLLLRL++C+EP   RQDVL+WLNEEK+IQRLVE++HPSQ+ED
Sbjct: 1   MDLLLRLVSCVEPAGLRQDVLHWLNEEKVIQRLVELIHPSQDED 44


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 58/289 (20%), Positives = 121/289 (41%), Gaps = 35/289 (12%)

Query: 485 NDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWE 544
           +D K A+ DD      D  SD N   N++ +GN                + G+D+ D  +
Sbjct: 505 SDSKGAEDDDS-----DSTSDTN---NSDSNGN---------------GNNGNDDNDKSD 541

Query: 545 E-KHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNW 603
             K  + + +S    SS S+DS +S+DS+  D       + S +++ D  + D S+  N 
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601

Query: 604 SANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVE 663
           S + D            S  SD   + +   +K     S S+ + S S  DS  SNS   
Sbjct: 602 SDSSD-----------SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 650

Query: 664 METSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLS 723
            + S       + +++  +   +++ S +   SS+  + ++S+D    +  +     + S
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710

Query: 724 LTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSS 772
            + D+   +    S+    ++S  +   ++ +  +++++  ++    SS
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 67/351 (19%), Positives = 137/351 (39%), Gaps = 25/351 (7%)

Query: 439 DEVRERWETFCTSSLGETNKRNTVDLAF-SDYQMQQMTSNFIDQFGFNDEKFADQDDIGN 497
           D  +   ++  + S  +++  N+ D +  SD      +SN  D    +D   +      +
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684

Query: 498 VSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRR 557
            S D  SD + + N++ES + +  ++   +     D   S+  D         +  S   
Sbjct: 685 NSSDS-SDSSDSSNSSESSDSS--DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGA 617
            SS S+DS  S+DS +   +        S+++ D  +   S   N S+N           
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN----------- 790

Query: 618 PLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPS 677
              S  SD  ++ +   + ++  +S S  + S ++ DS  S+   +   S++  D    S
Sbjct: 791 --SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848

Query: 678 AAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKS 737
             + +     + S     SSD  + + S+D    +  N       S + D+   +    S
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES-----SNSSDSSDSSNSSDS 903

Query: 738 EEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
           +    S S D++  D+    +++E+  ++    +SS    +   S   D+S
Sbjct: 904 DSSDSSNSSDSS--DSSNSSDSSESSNSSDN-SNSSDSSNSSDSSDSSDSS 951



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 56/325 (17%), Positives = 131/325 (40%), Gaps = 9/325 (2%)

Query: 450  TSSLGETNKRNTVDLAFSDYQMQQMTSNFIDQF-GFNDEKFADQDDIGNVSFDRVSDINF 508
            + S   ++  ++ D + SD      +SN  D     N    +D  D  + S    S+ + 
Sbjct: 801  SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860

Query: 509  TLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEES 568
            + N+++S + +              +  S+  D  +  + + +  S   +SS S+DS  S
Sbjct: 861  SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920

Query: 569  TDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWS 628
            +DS E   +  +     S+N+ D    D S+  N S + +    +      DS  SD   
Sbjct: 921  SDSSESSNSSDNSNSSDSSNSSDSS--DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978

Query: 629  TEEPMPTKETGWAS-FSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEA 687
            +     + ++  +S  S+ + S ++ DS  S+   +   S++  +    S ++     ++
Sbjct: 979  SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS-----DS 1033

Query: 688  AGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKSEEGKLSTSQD 747
            + S     SSD  + ++S+D    +  +     + S      ++++          +S  
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093

Query: 748  AACKDAEECPETAEAKCAAPRPPSS 772
            +   D+ +  +++++  ++    SS
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSS 1118



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 59/353 (16%), Positives = 136/353 (38%), Gaps = 20/353 (5%)

Query: 436 DLPDEVRERWETFCTSSLGETNKRNTVDLAFSDYQMQQMTSNFIDQFGFNDEKFADQDDI 495
           D  D  + + ++  + S   +N  ++ D + SD       SN       +D   +D  D 
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD----SSDSNSSSDSDSSDSDSSDSSDS 593

Query: 496 GNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQ 555
            +      SD + + ++++S + +       +      D    E D  +    + + +S 
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSS-------DSSDSKSDSSKSESDSSDSDSKSDSSDSN 646

Query: 556 RRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTH 615
              SS ++DS +S++S     +        S+++ D      S   + S+N     +++ 
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706

Query: 616 GAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLT 675
            +  DS  S   S      +  +  +  S+ ++S  + DS  S++  +   S++  +   
Sbjct: 707 SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD 766

Query: 676 PSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVF 735
            S ++     +++ S     SSD  + + S+D    +  N       S + D+   +   
Sbjct: 767 SSDSS-----DSSDSSDSSNSSDSNDSSNSSDSSDSS--NSSDSSNSSDSSDSSDSSDSD 819

Query: 736 KSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
            S     S S D++  D+    +++++  ++    S S  +     S+    S
Sbjct: 820 SSNSSDSSNSSDSS--DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS 870



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 53/302 (17%), Positives = 119/302 (39%), Gaps = 6/302 (1%)

Query: 490  ADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIA 549
            +D  D  N S    SD + + ++++S N +                 S+  D  +    +
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 550  FTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDV 609
             + +S   +SS S++S +S+DS   D +       SS +++     D S+  N S + D 
Sbjct: 952  NSSDSS--NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009

Query: 610  PMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
               +      DS  S   S+     +  +  +  S+ + S  + DS  S+   +   S++
Sbjct: 1010 SDSSDSSNSSDSSNSSD-SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068

Query: 670  PMDPLTPS-AAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              D    S ++  +   +++ S     SSD  + ++S+D    +  +     + S     
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPS--SSPEQRTGQPSAPGD 786
             ++++          +S  +   D+ +  +++++  ++    S  SS    +   S   D
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188

Query: 787  TS 788
            +S
Sbjct: 1189 SS 1190



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 50/237 (21%), Positives = 97/237 (40%), Gaps = 23/237 (9%)

Query: 554  SQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMET 613
            S    SS S+DS +S+DS + D         SS +++     D S+  N S + D     
Sbjct: 798  SNSSDSSNSSDSSDSSDSSDSD---------SSNSSDSSNSSDSSDSSNSSDSSD----- 843

Query: 614  THGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDP 673
               +   S GSD  S+     +  +  +  S+ ++S  + DS  SN   E   S++  D 
Sbjct: 844  ---SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN---ESSNSSDSSDS 897

Query: 674  LTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETA 733
               S +  +    ++ S     SSD  E + S+D  + +  +    ++   +  + +  +
Sbjct: 898  SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN-SNSSDSSNSSDSSDSSDSSNSSDS 956

Query: 734  VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPS--SSPEQRTGQPSAPGDTS 788
               S+    S S D+   D+ +   ++++  ++    S  SS    +   S   D+S
Sbjct: 957  SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 45/277 (16%), Positives = 110/277 (39%), Gaps = 12/277 (4%)

Query: 504  SDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRS----S 559
            SD + + N+++S N     +         D   SD  D       + + +S   S    S
Sbjct: 945  SDSSDSSNSSDSSN----SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000

Query: 560  SGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPL 619
            S S+DS +S+DS +   +        S+N+ D  +   S   + S++     ++++ +  
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060

Query: 620  DSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAA 679
                    S++    +  +  +  S+ + S ++ DS  S+   +   S++  D    S +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120

Query: 680  ALAVQP----EAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVF 735
            + +       +++ S     SSD  + +ES+D    +  +     + S      ++++  
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180

Query: 736  KSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSS 772
                    +S  +   D+ +  +++++  ++    SS
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 47/304 (15%), Positives = 119/304 (39%), Gaps = 5/304 (1%)

Query: 490  ADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIA 549
            +D  +  + S    SD + + N+++S + +                 SD  D  +  + +
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019

Query: 550  FTPESQRRS-SSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFD 608
             +  S   S SS S+DS +S+DS +   +       +S+++ D  +   S   + S++  
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079

Query: 609  VPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST 668
               E++  +   +      S++    +  +  +  S+ + S ++ DS  S+   +   S+
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139

Query: 669  EPMDPLTPSAAA----LAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSL 724
               D    S ++     +   +++ S     SSD  + + S+D    +  +     + S 
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199

Query: 725  TVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAP 784
                 ++++          +S  +   D+ +  E++++  ++    SS+    +    + 
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSS 1259

Query: 785  GDTS 788
              TS
Sbjct: 1260 DSTS 1263



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 51/242 (21%), Positives = 98/242 (40%), Gaps = 10/242 (4%)

Query: 467  SDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCK 526
            SD      +SN  D    +D   +      + S D  SD + + ++++S N +       
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSD 1065

Query: 527  ERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSS 586
                      SD  D  E    + +  S    SS S+DS +S+DS +   +       +S
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSS--DSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123

Query: 587  ANTEDKME-VDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSE 645
            +++ D  +  D S+  N S + D    +      DS  S   S++    +  +  ++ S+
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD-SSDSSDSSDSSDSSNSSD 1182

Query: 646  FTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAES 705
             + S  + DS  S+   +   S++  D    S ++     +++ S     SSD  E ++S
Sbjct: 1183 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSNESSDS 1237

Query: 706  TD 707
            +D
Sbjct: 1238 SD 1239



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 33/182 (18%), Positives = 77/182 (42%), Gaps = 2/182 (1%)

Query: 554  SQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMET 613
            S   +SS S+DS +S+DS +   +        S+++ D  +   S   + S++     ++
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 614  THGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD- 672
            ++ +          S++    +  +  +  S+ + S  + DS  S+   +   S E  D 
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237

Query: 673  -PLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTE 731
               + S+ +      +  S + +++SD  ++++S  K      NG   ++ S   D+   
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297

Query: 732  TA 733
            T+
Sbjct: 1298 TS 1299


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 62/266 (23%), Positives = 99/266 (37%), Gaps = 24/266 (9%)

Query: 533  DDGGSDEEDIWEEKHIAFTPESQRRSSS-GSTDSEESTDSEEEDGAKQDLFEPSSANTED 591
            ++    +E++ E K     P S+    +  +  S    +S E +GA QD  E  +A    
Sbjct: 1397 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL 1456

Query: 592  KMEVDLSEPPNWSANFDVPMETTHGAPLDSVGS----DVWSTEEP-MPTKETGWASFSEF 646
            +      E P  S   D    + H +P+ SV S     V S   P +P  E+G+   S  
Sbjct: 1457 QSYTQADEDPQMSMVEDCHA-SEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPE 1515

Query: 647  TSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAEST 706
              SLS        S   METS     P     +   V    +   ++E++++  E+  S 
Sbjct: 1516 QGSLSAP------SMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSY 1569

Query: 707  DKVT-----------ETVMNGGMKETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEE 755
            D               +   GG+  + SLT  +   T    S     S  Q ++ + A  
Sbjct: 1570 DSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAAN 1629

Query: 756  CPETAEAKCAAPRPPSSSPEQRTGQP 781
            C   +   C   RPPS+  +Q    P
Sbjct: 1630 CSIKSPQSCVVERPPSNQQQQPPPPP 1655



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 58/278 (20%), Positives = 98/278 (35%), Gaps = 58/278 (20%)

Query: 522  EACCKERIQQFDDGG-----SDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDG 576
            +AC  E I      G      + E+  E K     PE ++       ++EE+ + EEED 
Sbjct: 1185 QACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDA 1244

Query: 577  AKQDLFEPSSANTEDKMEVDLSEP---------------------------PNWSANFDV 609
            A  ++   S A++ +  E +  EP                           P      D 
Sbjct: 1245 ASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDA 1304

Query: 610  PMETTHGAPLDSVGSDVWSTE-------EPMPTK-----ETGWASFSEFTSSLSTKDSLR 657
              ET      D+   D    E       E  PT+     E G        +   +++ ++
Sbjct: 1305 AAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIK 1364

Query: 658  SNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGG 717
                 E+++  E      PS     V  + AGS       D EED+ + +++ E      
Sbjct: 1365 DKEETELDSEEE-----QPSHDTSVVSEQMAGS-----EDDHEEDSHTKEELIELKEE-- 1412

Query: 718  MKETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEE 755
             +E     +D +T  AV +S   + S+  + A +D EE
Sbjct: 1413 -EEIPHSELDLETVQAV-QSLTQEESSEHEGAYQDCEE 1448


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 62/266 (23%), Positives = 99/266 (37%), Gaps = 24/266 (9%)

Query: 533  DDGGSDEEDIWEEKHIAFTPESQRRSSS-GSTDSEESTDSEEEDGAKQDLFEPSSANTED 591
            ++    +E++ E K     P S+    +  +  S    +S E +GA QD  E  +A    
Sbjct: 1397 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL 1456

Query: 592  KMEVDLSEPPNWSANFDVPMETTHGAPLDSVGS----DVWSTEEP-MPTKETGWASFSEF 646
            +      E P  S   D    + H +P+ SV S     V S   P +P  E+G+   S  
Sbjct: 1457 QSYTQADEDPQMSMVEDCHA-SEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPE 1515

Query: 647  TSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAEST 706
              SLS        S   METS     P     +   V    +   ++E++++  E+  S 
Sbjct: 1516 QGSLSAP------SMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSY 1569

Query: 707  DKVT-----------ETVMNGGMKETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEE 755
            D               +   GG+  + SLT  +   T    S     S  Q ++ + A  
Sbjct: 1570 DSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAAN 1629

Query: 756  CPETAEAKCAAPRPPSSSPEQRTGQP 781
            C   +   C   RPPS+  +Q    P
Sbjct: 1630 CSIKSPQSCVVERPPSNQQQQPPPPP 1655



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 58/278 (20%), Positives = 98/278 (35%), Gaps = 58/278 (20%)

Query: 522  EACCKERIQQFDDGG-----SDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDG 576
            +AC  E I      G      + E+  E K     PE ++       ++EE+ + EEED 
Sbjct: 1185 QACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDA 1244

Query: 577  AKQDLFEPSSANTEDKMEVDLSEP---------------------------PNWSANFDV 609
            A  ++   S A++ +  E +  EP                           P      D 
Sbjct: 1245 ASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDA 1304

Query: 610  PMETTHGAPLDSVGSDVWSTE-------EPMPTK-----ETGWASFSEFTSSLSTKDSLR 657
              ET      D+   D    E       E  PT+     E G        +   +++ ++
Sbjct: 1305 AAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIK 1364

Query: 658  SNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGG 717
                 E+++  E      PS     V  + AGS       D EED+ + +++ E      
Sbjct: 1365 DKEETELDSEEE-----QPSHDTSVVSEQMAGS-----EDDHEEDSHTKEELIELKEE-- 1412

Query: 718  MKETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEE 755
             +E     +D +T  AV +S   + S+  + A +D EE
Sbjct: 1413 -EEIPHSELDLETVQAV-QSLTQEESSEHEGAYQDCEE 1448


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 62/266 (23%), Positives = 99/266 (37%), Gaps = 24/266 (9%)

Query: 533  DDGGSDEEDIWEEKHIAFTPESQRRSSS-GSTDSEESTDSEEEDGAKQDLFEPSSANTED 591
            ++    +E++ E K     P S+    +  +  S    +S E +GA QD  E  +A    
Sbjct: 1397 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTL 1456

Query: 592  KMEVDLSEPPNWSANFDVPMETTHGAPLDSVGS----DVWSTEEP-MPTKETGWASFSEF 646
            +      E P  S   D    + H +P+ SV S     V S   P +P  E+G+   S  
Sbjct: 1457 QSYTQADEDPQMSMVEDCHA-SEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPE 1515

Query: 647  TSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAEST 706
              SLS        S   METS     P     +   V    +   ++E++++  E+  S 
Sbjct: 1516 QGSLSAP------SMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSY 1569

Query: 707  DKVT-----------ETVMNGGMKETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEE 755
            D               +   GG+  + SLT  +   T    S     S  Q ++ + A  
Sbjct: 1570 DSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAAN 1629

Query: 756  CPETAEAKCAAPRPPSSSPEQRTGQP 781
            C   +   C   RPPS+  +Q    P
Sbjct: 1630 CSIKSPQSCVVERPPSNQQQQPPPPP 1655



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 58/278 (20%), Positives = 98/278 (35%), Gaps = 58/278 (20%)

Query: 522  EACCKERIQQFDDGG-----SDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDG 576
            +AC  E I      G      + E+  E K     PE ++       ++EE+ + EEED 
Sbjct: 1185 QACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDA 1244

Query: 577  AKQDLFEPSSANTEDKMEVDLSEP---------------------------PNWSANFDV 609
            A  ++   S A++ +  E +  EP                           P      D 
Sbjct: 1245 ASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDA 1304

Query: 610  PMETTHGAPLDSVGSDVWSTE-------EPMPTK-----ETGWASFSEFTSSLSTKDSLR 657
              ET      D+   D    E       E  PT+     E G        +   +++ ++
Sbjct: 1305 AAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIK 1364

Query: 658  SNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGG 717
                 E+++  E      PS     V  + AGS       D EED+ + +++ E      
Sbjct: 1365 DKEETELDSEEE-----QPSHDTSVVSEQMAGS-----EDDHEEDSHTKEELIELKEE-- 1412

Query: 718  MKETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEE 755
             +E     +D +T  AV +S   + S+  + A +D EE
Sbjct: 1413 -EEIPHSELDLETVQAV-QSLTQEESSEHEGAYQDCEE 1448


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 65/248 (26%), Positives = 102/248 (41%), Gaps = 32/248 (12%)

Query: 511 NTNESGNIALFE-----ACCKERIQQFDDGGS-DEEDIWEEKHIAFTPESQRRSSSGSTD 564
           NT +SG   L E        K RI + DD    D+ +  EE     T  S  R +  S  
Sbjct: 250 NTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQP 309

Query: 565 SEESTDSEEEDGAKQDLFEPSSAN-----TEDKMEVDLSEPPNWSANFDVPMETTHGAPL 619
             +S    +ED +K++L +  S N     +E   E +LS   N S + +  +  + G   
Sbjct: 310 RRDSKGDSQED-SKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNP 368

Query: 620 DSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE----PMDPLT 675
           D   S V   E+   ++E    + S  + S S ++   S S   +  S E    P D  +
Sbjct: 369 DPTTSYVEDQEDSDSSEEDSSHTLSH-SKSESREEQADSESSESLNFSEESPESPEDENS 427

Query: 676 PSAAALAVQPEAAGSVAMEA-----------SSDGEEDAESTDKVTETVMNGGMK----E 720
            S   L     +A S + E+           SS  +ED+ ST+  + +  +G +K    E
Sbjct: 428 SSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIE 487

Query: 721 TLSLTVDA 728
           +  LTVDA
Sbjct: 488 SRKLTVDA 495


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 65/248 (26%), Positives = 102/248 (41%), Gaps = 32/248 (12%)

Query: 511 NTNESGNIALFE-----ACCKERIQQFDDGGS-DEEDIWEEKHIAFTPESQRRSSSGSTD 564
           NT +SG   L E        K RI + DD    D+ +  EE     T  S  R +  S  
Sbjct: 234 NTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQP 293

Query: 565 SEESTDSEEEDGAKQDLFEPSSAN-----TEDKMEVDLSEPPNWSANFDVPMETTHGAPL 619
             +S    +ED +K++L +  S N     +E   E +LS   N S + +  +  + G   
Sbjct: 294 RRDSKGDSQED-SKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNP 352

Query: 620 DSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE----PMDPLT 675
           D   S V   E+   ++E    + S  + S S ++   S S   +  S E    P D  +
Sbjct: 353 DPTTSYVEDQEDSDSSEEDSSHTLSH-SKSESREEQADSESSESLNFSEESPESPEDENS 411

Query: 676 PSAAALAVQPEAAGSVAMEA-----------SSDGEEDAESTDKVTETVMNGGMK----E 720
            S   L     +A S + E+           SS  +ED+ ST+  + +  +G +K    E
Sbjct: 412 SSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIE 471

Query: 721 TLSLTVDA 728
           +  LTVDA
Sbjct: 472 SRKLTVDA 479


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 21/221 (9%)

Query: 570  DSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSV----GSD 625
            +S E+D   QD  E   A    +      + P  +   D   ++ H +P+ SV    G  
Sbjct: 1551 ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS 1610

Query: 626  VWSTEEP-MPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQ 684
            V S   P +P  E  +A  S   S++S        S   METS     P     +   V 
Sbjct: 1611 VRSVNSPSVPALENSYAQISPDQSAISVP------SLQNMETSPMMDVPSVSDHSQQVVD 1664

Query: 685  PEAAGSVAMEASSDGEEDAESTDKVTETVM--NGGMKETLS---LTVDAKTETAVFKSEE 739
               +   ++E++++  E+  S D      +  NG  + + S   LT  + T+++   +++
Sbjct: 1665 SGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQ 1724

Query: 740  -----GKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPE 775
                 G  S  Q  +      C   +   C   RPPSSS +
Sbjct: 1725 MSNISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQ 1765



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 55/224 (24%), Positives = 84/224 (37%), Gaps = 18/224 (8%)

Query: 552  PESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFD--- 608
            PE +        + EE  + EEE+G      +P  A +++K E ++S     SA  D   
Sbjct: 1350 PEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHE 1409

Query: 609  ----VPMETTHGAPLDSVGSDVWSTEE-PMPTKETGWASFSEFTSSLSTKDSL-----RS 658
                   E +H    D+   D    E   +  +E    SF E   +  T   L      S
Sbjct: 1410 EEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHS 1469

Query: 659  NSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGM 718
            N  V M+   +           LA  PEA    + E    GE+ A+  D+     ++   
Sbjct: 1470 NPEVLMDCGVDLTASCNSEPKELAGDPEAVPE-SDEEPPPGEQ-AQKQDQKNSKEVDTEF 1527

Query: 719  KETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEA 762
            KE    T++  +ET        + S+ QD   +D   C ET EA
Sbjct: 1528 KEGNPATMEIDSETVQAVQSLTQESSEQDDTFQD---CAETQEA 1568


>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
           sapiens]
          Length = 776

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 58/249 (23%), Positives = 92/249 (36%), Gaps = 29/249 (11%)

Query: 547 HIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANT-EDKMEVDLSEPPNWSA 605
           H+  TP  Q+  +     SEE        GA  +  E    +  ED  E DL EP     
Sbjct: 304 HVEITPNVQKEQAH----SEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQ- 358

Query: 606 NFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEME 665
               P     G P+    S V   +  M +K        +  +  ST+ S ++   ++  
Sbjct: 359 ----PAAAPRGKPV----SRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKT---LKNR 407

Query: 666 TSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLT 725
               P  P TP ++   +QP +        SS      +    VT    + G KE     
Sbjct: 408 PCLSPKHP-TPGSSDPLIQPSSPAVCPEPPSSP-----KHVSSVTSRTGSSGAKEMKLKG 461

Query: 726 VDAKTETAVFKS-----EEGKLSTSQ-DAACKDAEECPETAEAKCAAPRPPSSSPEQRTG 779
            D KT+ A  +      ++G+ + ++  A    A + P ++  K    RPP + P    G
Sbjct: 462 ADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERG 521

Query: 780 QPSAPGDTS 788
           +P   GD S
Sbjct: 522 EPPKSGDRS 530


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 63/301 (20%), Positives = 110/301 (36%), Gaps = 70/301 (23%)

Query: 531  QFDDGG--------SDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLF 582
            + D GG        S+E++  EE+  A   E +       +D  + +++++ED A  +  
Sbjct: 1028 ELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEAS 1087

Query: 583  EPSSANTED---------KMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPM 633
            E    ++++         K E   S   + S+ F+   E++  +  D    +V + EE  
Sbjct: 1088 EKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDE--EEVVAREEEE 1145

Query: 634  PTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAM 693
              +E            +  ++S+ S  P + E   E         AALA    A  S+ M
Sbjct: 1146 EEEE----------EEMVAEESMASAGPEDFEQDGE--------EAALAPGAPAVDSLGM 1187

Query: 694  EASSDGEEDA----ESTDKVTETVMNGGMKETLSLTVDAKTETAVFKSEEGKLSTSQDAA 749
            E   D E +A    E    + E  +  G++E    + +   E  +  S+EG +  S +  
Sbjct: 1188 EEEVDIETEAVAPEERPSMLDEPPLPVGVEEPAD-SREPPEEPGL--SQEGAMLLSPEPP 1244

Query: 750  CKDAEECPETAEAKC--------------------------AAPRPPSSSPEQRTGQPSA 783
             K+ E  P  +  +                             PRPPS  PE  T   S 
Sbjct: 1245 AKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASH 1304

Query: 784  P 784
            P
Sbjct: 1305 P 1305


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 56/251 (22%), Positives = 95/251 (37%), Gaps = 24/251 (9%)

Query: 559  SSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAP 618
            ++GS  +  ST+  E         E ++A+T D     +S   + +         T    
Sbjct: 1048 TTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVY 1107

Query: 619  LDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSA 678
            +    +   STE    T  T   + SE T++ +T   + +      ET+T        + 
Sbjct: 1108 ITGSKTTTASTEGSEAT--TVSTTSSETTTASTTGSEMTTVFTTVSETTT------VSTI 1159

Query: 679  AALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK 736
             + A    AAGS A   S++G E   A +    T T    G + T + T  ++T TA   
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTS 1219

Query: 737  SEE-------GKLSTSQDAACKDAEEC----PETAEAKCAAPRPPSSS---PEQRTGQPS 782
              E       G  +++  +A  +         ET  A  A+  P ++S    E  T   +
Sbjct: 1220 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1279

Query: 783  APGDTSVNGPV 793
            A G T+ +  V
Sbjct: 1280 ASGATAASTTV 1290


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 48/231 (20%), Positives = 86/231 (37%), Gaps = 15/231 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S++GS  +  ST   E   A  +  E ++ ++       +S     +   +  + 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS-----TTGTETTIT 1026

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
            +T G+   +V   GS+  +         T     SE T+  +T     + S  ++ET+T 
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 670  PMDPLTPSAAALAVQPEAA----GSVAMEASSDGEED---AESTDKVTETVMNGGMKETL 722
                   + A+ A          GS    AS++G E    + ++ + T     G    T+
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 723  SLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
              TV   T  +   SE    S +   A   + E  ET  A  A     ++S
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 48/231 (20%), Positives = 86/231 (37%), Gaps = 15/231 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S++GS  +  ST   E   A  +  E ++ ++       +S     +   +  + 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS-----TTGTETTIT 1026

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
            +T G+   +V   GS+  +         T     SE T+  +T     + S  ++ET+T 
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 670  PMDPLTPSAAALAVQPEAA----GSVAMEASSDGEED---AESTDKVTETVMNGGMKETL 722
                   + A+ A          GS    AS++G E    + ++ + T     G    T+
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 723  SLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
              TV   T  +   SE    S +   A   + E  ET  A  A     ++S
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 623 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 678

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 679 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 734

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 735 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 792

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 793 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 849

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 850 GSETIPASTA 859



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 747 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 806

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 807 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 866

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 867 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 926

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 927 ASTEGSEITTVSTTGSETTTASTEGSETTTA 957



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 214 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 273

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 274 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 333

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 334 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 393

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 394 TTTA---STEGSETTTASTEGSEA 414



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 580 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 633

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 634 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 693

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 694 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 753

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 754 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 793



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 873  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 927

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 928  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 987

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 988  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1041

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1042 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1100



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 48/231 (20%), Positives = 86/231 (37%), Gaps = 15/231 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S++GS  +  ST   E   A  +  E ++ ++       +S     +   +  + 
Sbjct: 993  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS-----TTGTETTIT 1047

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
            +T G+   +V   GS+  +         T     SE T+  +T     + S  ++ET+T 
Sbjct: 1048 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1107

Query: 670  PMDPLTPSAAALAVQPEAA----GSVAMEASSDGEED---AESTDKVTETVMNGGMKETL 722
                   + A+ A          GS    AS++G E    + ++ + T     G    T+
Sbjct: 1108 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1167

Query: 723  SLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
              TV   T  +   SE    S +   A   + E  ET  A  A     ++S
Sbjct: 1168 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1218



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 53/249 (21%), Positives = 87/249 (34%), Gaps = 28/249 (11%)

Query: 558 SSSGSTDSEESTDSEEE---DGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETT 614
           S SGS  +  ST   E      A       S A +E  +    SE         V +  T
Sbjct: 80  SISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTT------VSITGT 133

Query: 615 HGAPLDSVGSDVWS----TEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEP 670
               + ++GS+  +    + E   T   G  + +  T    T  +  ++S     ++T  
Sbjct: 134 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGS 193

Query: 671 MDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
                 +A +  + P  AGS     S+ G E        T TV   G + T + T  ++T
Sbjct: 194 EMTTVFTAGSETITPSTAGSETTTVSTAGSE--------TTTVSTTGSETTTASTAHSET 245

Query: 731 ETA-VFKSEEGKLSTS------QDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSA 783
             A    SE  K+ST+        A  +      E +E   A      ++    TG  + 
Sbjct: 246 TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETT 305

Query: 784 PGDTSVNGP 792
              T+ + P
Sbjct: 306 AASTTGSEP 314


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 48/231 (20%), Positives = 86/231 (37%), Gaps = 15/231 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S++GS  +  ST   E   A  +  E ++ ++       +S     +   +  + 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS-----TTGTETTIT 1026

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
            +T G+   +V   GS+  +         T     SE T+  +T     + S  ++ET+T 
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 670  PMDPLTPSAAALAVQPEAA----GSVAMEASSDGEED---AESTDKVTETVMNGGMKETL 722
                   + A+ A          GS    AS++G E    + ++ + T     G    T+
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 723  SLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
              TV   T  +   SE    S +   A   + E  ET  A  A     ++S
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 48/231 (20%), Positives = 86/231 (37%), Gaps = 15/231 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S++GS  +  ST   E   A  +  E ++ ++       +S     +   +  + 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS-----TTGTETTIT 1026

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
            +T G+   +V   GS+  +         T     SE T+  +T     + S  ++ET+T 
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 670  PMDPLTPSAAALAVQPEAA----GSVAMEASSDGEED---AESTDKVTETVMNGGMKETL 722
                   + A+ A          GS    AS++G E    + ++ + T     G    T+
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 723  SLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
              TV   T  +   SE    S +   A   + E  ET  A  A     ++S
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 56/251 (22%), Positives = 95/251 (37%), Gaps = 24/251 (9%)

Query: 559  SSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAP 618
            ++GS  +  ST+  E         E ++A+T D     +S   + +         T    
Sbjct: 1048 TTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVY 1107

Query: 619  LDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSA 678
            +    +   STE    T  T   + SE T++ +T   + +      ET+T        + 
Sbjct: 1108 ITGSKTTTASTEGSEAT--TVSTTSSETTTASTTGSEMTTVFTTVSETTT------VSTI 1159

Query: 679  AALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK 736
             + A    AAGS A   S++G E   A +    T T    G + T + T  ++T TA   
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTS 1219

Query: 737  SEE-------GKLSTSQDAACKDAEEC----PETAEAKCAAPRPPSSS---PEQRTGQPS 782
              E       G  +++  +A  +         ET  A  A+  P ++S    E  T   +
Sbjct: 1220 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1279

Query: 783  APGDTSVNGPV 793
            A G T+ +  V
Sbjct: 1280 ASGATAASTTV 1290


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 56/251 (22%), Positives = 95/251 (37%), Gaps = 24/251 (9%)

Query: 559  SSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAP 618
            ++GS  +  ST+  E         E ++A+T D     +S   + +         T    
Sbjct: 1048 TTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVY 1107

Query: 619  LDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSA 678
            +    +   STE    T  T   + SE T++ +T   + +      ET+T        + 
Sbjct: 1108 ITGSKTTTASTEGSEAT--TVSTTSSETTTASTTGSEMTTVFTTVSETTT------VSTI 1159

Query: 679  AALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAKTETAVFK 736
             + A    AAGS A   S++G E   A +    T T    G + T + T  ++T TA   
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTS 1219

Query: 737  SEE-------GKLSTSQDAACKDAEEC----PETAEAKCAAPRPPSSS---PEQRTGQPS 782
              E       G  +++  +A  +         ET  A  A+  P ++S    E  T   +
Sbjct: 1220 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1279

Query: 783  APGDTSVNGPV 793
            A G T+ +  V
Sbjct: 1280 ASGATAASTTV 1290


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 T--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 11/223 (4%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSA--AALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKT 730
             T SA  +   V  E +G+  +  +        +T   T T    G + T +    ++T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 731 ETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
            TA   S EG  +T+      +      T      A    S +
Sbjct: 733 TTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 48/231 (20%), Positives = 86/231 (37%), Gaps = 15/231 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S++GS  +  ST   E   A  +  E ++ ++       +S     +   +  + 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS-----TTGTETTIT 1026

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
            +T G+   +V   GS+  +         T     SE T+  +T     + S  ++ET+T 
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 670  PMDPLTPSAAALAVQPEAA----GSVAMEASSDGEED---AESTDKVTETVMNGGMKETL 722
                   + A+ A          GS    AS++G E    + ++ + T     G    T+
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 723  SLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
              TV   T  +   SE    S +   A   + E  ET  A  A     ++S
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 42/177 (23%), Positives = 74/177 (41%), Gaps = 15/177 (8%)

Query: 544 EEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNW 603
           E++H+A      +R+  G  D+E +    ++D + +D  +P SAN  +   + L    N 
Sbjct: 79  EDEHLA------KRARQGEEDNEYTESYSDDDSSMEDYPDPQSANHMNSSLLSLYRKGNP 132

Query: 604 SANFDVP----METTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSN 659
            +  + P     ETT   P  S  +     + P    E GW  F + T S+  KDS   +
Sbjct: 133 DSVSNTPEMEQRETTSSTPRISSKTGSIPLKTPAKDSEGGW--FIDKTPSVK-KDSFFLD 189

Query: 660 SPVEMETSTEPMDPLTPS--AAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVM 714
              E     +P+  +  S  ++ L    +  G +  + S   +ED +  D   E V+
Sbjct: 190 LSCEKSNPKKPITEIQDSKDSSLLESDMKRKGKLKNKGSKRKKEDLQEVDGEIEAVL 246


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 19/250 (7%)

Query: 545 EKHIAFTPESQRRSSS--GSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPN 602
           E   A T +S+  S+S  GS  +  ST S E   A  +  E ++ +T D     +S    
Sbjct: 602 ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---- 657

Query: 603 WSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPV 662
            +   +  + +T G+   +V +    +E  + T+ +G  + S  T S +TK S   +   
Sbjct: 658 -TTGSERTITSTEGSETTTVSAT--GSETTVSTEGSGTTTVS-ITGSETTKVSTTGSETT 713

Query: 663 EMETSTEPMDPLTPS-AAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMK 719
              TSTE  +  T S   +        GS    AS++G E   A +T   T T      +
Sbjct: 714 I--TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 720 ETLSLTVDAKTETA-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRT 778
            T++  + ++T  A    SE  K+ST   A+ K      E +E   A+     ++     
Sbjct: 772 TTMASIMGSETTMASTIGSETTKVST---ASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 779 GQPSAPGDTS 788
           G  + P  T+
Sbjct: 829 GSETIPASTA 838



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 48/211 (22%), Positives = 81/211 (38%), Gaps = 6/211 (2%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVP-METTHG 616
           S +GS  +  ST+  E   A  +  E +SA+T        S   + +    +   ETT  
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785

Query: 617 APLDSVGSDVWSTEEPMPT--KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPL 674
           + + S  + V +    M T   E    + +  T+S +T  S   +  +   T+       
Sbjct: 786 STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 675 TPSAAALAVQPEAAGSVAMEASSDGEEDAEST--DKVTETVMNGGMKETLSLTVDAKTET 732
           T +  +        GS    AS++  E   +T     T T    G + T + T  ++T T
Sbjct: 846 TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 733 AVFK-SEEGKLSTSQDAACKDAEECPETAEA 762
           A  + SE   +ST+       + E  ET  A
Sbjct: 906 ASTEGSEITTVSTTGSETTTASTEGSETTTA 936



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 6/204 (2%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E+   S++GS  +  ST   E   A     E ++A+T       +S   + +       E
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKET-GWASFSEFTSSLSTKDSLRSNSPVEMETSTEPM 671
           TT  +  DS  +  ++ +    T  T G+ + +  T+      +    S   M ++  P 
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312

Query: 672 DPLTPSAAALAVQPEAAGSVAMEASSDGEE--DAESTDKVTETVMNGGMKETLSLTVDAK 729
                +A++      AAGS  + AS+ G E     +T   T T    G + +   T  ++
Sbjct: 313 TTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE 372

Query: 730 TETAVFKSEEGKLSTSQDAACKDA 753
           T TA   S EG  +T+      +A
Sbjct: 373 TTTA---STEGSETTTASTEGSEA 393



 Score = 37.0 bits (84), Expect = 0.072
 Identities = 51/222 (22%), Positives = 81/222 (36%), Gaps = 15/222 (6%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E    ++  +T +E +TDS E  G        S   T     V  ++  N +A+     E
Sbjct: 559 EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT-----VSTADSENTTAS-TADSE 612

Query: 613 TTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMD 672
           TT  +   S  +   +T     T  T  +  +  +++ S    + +       TSTE  +
Sbjct: 613 TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 673 PLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTET 732
             T SA          GS     S  G E    T KV+ T    G + T++ T  ++  T
Sbjct: 673 TTTVSATGSETTVSTEGSGTTTVSITGSE----TTKVSTT----GSETTITSTEGSEITT 724

Query: 733 A-VFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
           A +  SE    ST        + E  ET  A        ++S
Sbjct: 725 ASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 50/240 (20%), Positives = 90/240 (37%), Gaps = 16/240 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S+ GS  +  ST+S E   A     E ++A+TE       S     +   +    
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS-----TEGSETTTA 906

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST- 668
            +T G+ + +V   GS+  +         T     SE T+  +T     + S    ET+T 
Sbjct: 907  STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 669  EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
              M   T +A+    +     +   E ++   E +E+T     TV + G + T   T   
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT-----TVSSTGSETTTVSTTG- 1020

Query: 729  KTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTS 788
             TET +  +E  + +T   A  +        +E    +     ++    TG  +    T+
Sbjct: 1021 -TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 48/231 (20%), Positives = 86/231 (37%), Gaps = 15/231 (6%)

Query: 553  ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
            E+   S++GS  +  ST   E   A  +  E ++ ++       +S     +   +  + 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS-----TTGTETTIT 1026

Query: 613  TTHGAPLDSV---GSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTE 669
            +T G+   +V   GS+  +         T     SE T+  +T     + S  ++ET+T 
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 670  PMDPLTPSAAALAVQPEAA----GSVAMEASSDGEED---AESTDKVTETVMNGGMKETL 722
                   + A+ A          GS    AS++G E    + ++ + T     G    T+
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 723  SLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSS 773
              TV   T  +   SE    S +   A   + E  ET  A  A     ++S
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/234 (19%), Positives = 96/234 (41%), Gaps = 24/234 (10%)

Query: 554 SQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMET 613
           S   SSS ST+ EE       +  + +   PS +  ED + ++ S  P  +AN ++ + +
Sbjct: 262 SSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTS 321

Query: 614 THGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSS----------LSTK-DSLRSNSPV 662
           T          + + +   +    + W+  S   +S          +ST    LR N+  
Sbjct: 322 TDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAAE 381

Query: 663 EMETSTEPMDP-LTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKET 721
            ++ + +  +P + P+ +A       + S+     S  E+ +++   VT +  +   + +
Sbjct: 382 VVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETS 441

Query: 722 LSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPE 775
            +LT ++ T T++   ++ + +TS             T     A PR PS  P+
Sbjct: 442 ATLTSNSTTGTSI--GDDSRRTTSSAV----------TETGPPAMPRLPSCCPQ 483


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 58/269 (21%), Positives = 101/269 (37%), Gaps = 40/269 (14%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGA 617
           SS  ++ S + TD E +   K    + SS +T++      +  P      DV  +   GA
Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG--DVTPQVKGGA 256

Query: 618 PLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPS 677
              +  +     EE   + E G  S SE  +   T+  ++++  +    +       TP 
Sbjct: 257 LPPAKRAK--KPEEESESSEEG--SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312

Query: 678 AAALAVQPEAAGSVAM---------------EASSDGEEDAESTDKVTETVMNGGMKETL 722
             A    P  AG+VA                E SSD EE+  +   + +   +G   +  
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372

Query: 723 SLTVDA--------------KTETAVFKSEEGKLSTSQDAACKDA---EECPETAEAKCA 765
           + +  A              KT  AV K++ GK      ++ +++   EE P  A+    
Sbjct: 373 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432

Query: 766 AP--RPPSSSPEQRTGQPSAPGDTSVNGP 792
           AP  R  S+  ++   + +AP      GP
Sbjct: 433 APQVRAASAPAKESPRKGAAPAPPRKTGP 461



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 53/250 (21%), Positives = 90/250 (36%), Gaps = 32/250 (12%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E   +SSS  +DSEE   ++ +   K      +SA  +        E P   A    P +
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK--------ESPRKGAAPAPPRK 458

Query: 613 TTHGAPLDSVGSDV----WSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST 668
           T   A    VG        S+EE    +E   A  +     L     ++  S + M    
Sbjct: 459 TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 518

Query: 669 EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
           +   P+ P     A      G    ++ S  EE ++S+D    T +    +++L   + A
Sbjct: 519 KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578

Query: 729 KTETAVFKSEEGKL-----------------STSQDAACKDAEECP---ETAEAKCAAPR 768
           K  ++  K    K                  S+ + +   D+EE P     A+AK A   
Sbjct: 579 KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638

Query: 769 PPSSSPEQRT 778
           P + +  ++T
Sbjct: 639 PQTKACPKKT 648



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 57/251 (22%), Positives = 93/251 (37%), Gaps = 16/251 (6%)

Query: 546  KHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSA 605
            K +A   ++Q      S  SEE +DSEEE      +      +          E P   A
Sbjct: 852  KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911

Query: 606  NFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEME 665
                P +T   A       D  S+ E     ++   + +  TS+   K  L     + ++
Sbjct: 912  APTPPGKTGPSAAQAGKQDDSGSSSE---ESDSDGEAPAAVTSAQVIKPPL-----IFVD 963

Query: 666  TSTEPMDP-LTPSAAALAVQP-EAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLS 723
             +  P  P  TP+ A  A  P +A  S +   SS  E + E     T+  +  G++  + 
Sbjct: 964  PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ-CLTPGIRTNVV 1022

Query: 724  LTVDAKTETAVFKSEEGKLSTSQDAACKDA--EECPETAEAKCAAPRPPSSSPEQRTGQP 781
                A    A   S  G  S+ + +   D   +E P T +   A    P++SP+  + Q 
Sbjct: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPAT-QVDSAVGTLPATSPQSTSVQ- 1080

Query: 782  SAPGDTSVNGP 792
             A G   +  P
Sbjct: 1081 -AKGTNKLRKP 1090


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 58/269 (21%), Positives = 101/269 (37%), Gaps = 40/269 (14%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGA 617
           SS  ++ S + TD E +   K    + SS +T++      +  P      DV  +   GA
Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG--DVTPQVKGGA 256

Query: 618 PLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPS 677
              +  +     EE   + E G  S SE  +   T+  ++++  +    +       TP 
Sbjct: 257 LPPAKRAK--KPEEESESSEEG--SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312

Query: 678 AAALAVQPEAAGSVAM---------------EASSDGEEDAESTDKVTETVMNGGMKETL 722
             A    P  AG+VA                E SSD EE+  +   + +   +G   +  
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372

Query: 723 SLTVDA--------------KTETAVFKSEEGKLSTSQDAACKDA---EECPETAEAKCA 765
           + +  A              KT  AV K++ GK      ++ +++   EE P  A+    
Sbjct: 373 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432

Query: 766 AP--RPPSSSPEQRTGQPSAPGDTSVNGP 792
           AP  R  S+  ++   + +AP      GP
Sbjct: 433 APQVRAASAPAKESPRKGAAPAPPRKTGP 461



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 53/250 (21%), Positives = 90/250 (36%), Gaps = 32/250 (12%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E   +SSS  +DSEE   ++ +   K      +SA  +        E P   A    P +
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK--------ESPRKGAAPAPPRK 458

Query: 613 TTHGAPLDSVGSDV----WSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST 668
           T   A    VG        S+EE    +E   A  +     L     ++  S + M    
Sbjct: 459 TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 518

Query: 669 EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
           +   P+ P     A      G    ++ S  EE ++S+D    T +    +++L   + A
Sbjct: 519 KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578

Query: 729 KTETAVFKSEEGKL-----------------STSQDAACKDAEECP---ETAEAKCAAPR 768
           K  ++  K    K                  S+ + +   D+EE P     A+AK A   
Sbjct: 579 KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638

Query: 769 PPSSSPEQRT 778
           P + +  ++T
Sbjct: 639 PQTKACPKKT 648



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 58/262 (22%), Positives = 93/262 (35%), Gaps = 27/262 (10%)

Query: 546  KHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSA 605
            K +A   ++Q      S  SEE +DSEEE      +      +          E P   A
Sbjct: 852  KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911

Query: 606  NFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEME 665
                P +T   A       D  S+ E     ++   + +  TS+   K  L     + ++
Sbjct: 912  APTPPGKTGPSAAQAGKQDDSGSSSE---ESDSDGEAPAAVTSAQVIKPPL-----IFVD 963

Query: 666  TSTEPMDP-LTPSAAALAVQP-EAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLS 723
             +  P  P  TP+ A  A  P +A  S +   SS  E + E     T+  +  G++  + 
Sbjct: 964  PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ-CLTPGIRTNVV 1022

Query: 724  LTVDAKTETAVFKSEEGKLSTSQDAACKDA--EECPET--------------AEAKCAAP 767
                A    A   S  G  S+ + +   D   +E P T              A  K  A 
Sbjct: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ 1082

Query: 768  RPPSSSPEQRTGQPSAPGDTSV 789
            +   + P     QPS+  D++V
Sbjct: 1083 KASEAQPPVARTQPSSGVDSAV 1104


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 58/269 (21%), Positives = 101/269 (37%), Gaps = 40/269 (14%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGA 617
           SS  ++ S + TD E +   K    + SS +T++      +  P      DV  +   GA
Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG--DVTPQVKGGA 256

Query: 618 PLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPS 677
              +  +     EE   + E G  S SE  +   T+  ++++  +    +       TP 
Sbjct: 257 LPPAKRAK--KPEEESESSEEG--SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312

Query: 678 AAALAVQPEAAGSVAM---------------EASSDGEEDAESTDKVTETVMNGGMKETL 722
             A    P  AG+VA                E SSD EE+  +   + +   +G   +  
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372

Query: 723 SLTVDA--------------KTETAVFKSEEGKLSTSQDAACKDA---EECPETAEAKCA 765
           + +  A              KT  AV K++ GK      ++ +++   EE P  A+    
Sbjct: 373 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432

Query: 766 AP--RPPSSSPEQRTGQPSAPGDTSVNGP 792
           AP  R  S+  ++   + +AP      GP
Sbjct: 433 APQVRAASAPAKESPRKGAAPAPPRKTGP 461



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 53/250 (21%), Positives = 90/250 (36%), Gaps = 32/250 (12%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E   +SSS  +DSEE   ++ +   K      +SA  +        E P   A    P +
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK--------ESPRKGAAPAPPRK 458

Query: 613 TTHGAPLDSVGSDV----WSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST 668
           T   A    VG        S+EE    +E   A  +     L     ++  S + M    
Sbjct: 459 TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 518

Query: 669 EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
           +   P+ P     A      G    ++ S  EE ++S+D    T +    +++L   + A
Sbjct: 519 KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578

Query: 729 KTETAVFKSEEGKL-----------------STSQDAACKDAEECP---ETAEAKCAAPR 768
           K  ++  K    K                  S+ + +   D+EE P     A+AK A   
Sbjct: 579 KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638

Query: 769 PPSSSPEQRT 778
           P + +  ++T
Sbjct: 639 PQTKACPKKT 648



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 57/251 (22%), Positives = 93/251 (37%), Gaps = 16/251 (6%)

Query: 546  KHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSA 605
            K +A   ++Q      S  SEE +DSEEE      +      +          E P   A
Sbjct: 852  KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911

Query: 606  NFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEME 665
                P +T   A       D  S+ E     ++   + +  TS+   K  L     + ++
Sbjct: 912  APTPPGKTGPSAAQAGKQDDSGSSSE---ESDSDGEAPAAVTSAQVIKPPL-----IFVD 963

Query: 666  TSTEPMDP-LTPSAAALAVQP-EAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLS 723
             +  P  P  TP+ A  A  P +A  S +   SS  E + E     T+  +  G++  + 
Sbjct: 964  PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ-CLTPGIRTNVV 1022

Query: 724  LTVDAKTETAVFKSEEGKLSTSQDAACKDA--EECPETAEAKCAAPRPPSSSPEQRTGQP 781
                A    A   S  G  S+ + +   D   +E P T +   A    P++SP+  + Q 
Sbjct: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPAT-QVDSAVGTLPATSPQSTSVQ- 1080

Query: 782  SAPGDTSVNGP 792
             A G   +  P
Sbjct: 1081 -AKGTNKLRKP 1090


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 58/269 (21%), Positives = 101/269 (37%), Gaps = 40/269 (14%)

Query: 558 SSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGA 617
           SS  ++ S + TD E +   K    + SS +T++      +  P      DV  +   GA
Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG--DVTPQVKGGA 256

Query: 618 PLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPS 677
              +  +     EE   + E G  S SE  +   T+  ++++  +    +       TP 
Sbjct: 257 LPPAKRAK--KPEEESESSEEG--SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312

Query: 678 AAALAVQPEAAGSVAM---------------EASSDGEEDAESTDKVTETVMNGGMKETL 722
             A    P  AG+VA                E SSD EE+  +   + +   +G   +  
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372

Query: 723 SLTVDA--------------KTETAVFKSEEGKLSTSQDAACKDA---EECPETAEAKCA 765
           + +  A              KT  AV K++ GK      ++ +++   EE P  A+    
Sbjct: 373 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432

Query: 766 AP--RPPSSSPEQRTGQPSAPGDTSVNGP 792
           AP  R  S+  ++   + +AP      GP
Sbjct: 433 APQVRAASAPAKESPRKGAAPAPPRKTGP 461



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 53/250 (21%), Positives = 90/250 (36%), Gaps = 32/250 (12%)

Query: 553 ESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPME 612
           E   +SSS  +DSEE   ++ +   K      +SA  +        E P   A    P +
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK--------ESPRKGAAPAPPRK 458

Query: 613 TTHGAPLDSVGSDV----WSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETST 668
           T   A    VG        S+EE    +E   A  +     L     ++  S + M    
Sbjct: 459 TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 518

Query: 669 EPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDA 728
           +   P+ P     A      G    ++ S  EE ++S+D    T +    +++L   + A
Sbjct: 519 KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578

Query: 729 KTETAVFKSEEGKL-----------------STSQDAACKDAEECP---ETAEAKCAAPR 768
           K  ++  K    K                  S+ + +   D+EE P     A+AK A   
Sbjct: 579 KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638

Query: 769 PPSSSPEQRT 778
           P + +  ++T
Sbjct: 639 PQTKACPKKT 648


>gi|147903302 MAP7 domain containing 3 [Homo sapiens]
          Length = 876

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 60/238 (25%), Positives = 92/238 (38%), Gaps = 31/238 (13%)

Query: 563 TDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSV 622
           T  EES   + E   K  +  P   N E      +   P        P  +T   P+ SV
Sbjct: 285 TKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGM-APEVSTDSFPVVSV 343

Query: 623 G-SDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAAL 681
             S V ST +            SE +   S + S+ +   V++ET  +     +P A+  
Sbjct: 344 DVSPVVSTYD------------SEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLE 391

Query: 682 A---VQPEAAGSVAMEASSDGEEDAE---STDKVTETVMNGGMKETLSLTVDAKTETAVF 735
           A   V  EA   V++EA+ +G  +A    S +   +  + G  KE++  + +A  + +  
Sbjct: 392 APPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPK 451

Query: 736 KSEEGKLSTSQDAACKDA---EECPETAEAKCAAPRPP--------SSSPEQRTGQPS 782
            S E  +  S  A  +DA    E  + A    A  R          SSSPE   G PS
Sbjct: 452 TSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPS 509


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,649,039
Number of Sequences: 37866
Number of extensions: 1562478
Number of successful extensions: 8248
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 228
Number of HSP's that attempted gapping in prelim test: 7028
Number of HSP's gapped (non-prelim): 982
length of query: 793
length of database: 18,247,518
effective HSP length: 110
effective length of query: 683
effective length of database: 14,082,258
effective search space: 9618182214
effective search space used: 9618182214
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.