Guide to the Human Genome
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Name: MAP2K2 Sequence: fasta or formatted (400aa) NCBI GI: 13489054
Description:

mitogen-activated protein kinase kinase 2

Referenced in:

MAP Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         25           1
 C cysteine            1.2          5           1
 D aspartate           4.8         19           3
 E glutamate           8.8         35           2
 F phenylalanine       3.2         13           1
 G glycine             7.8         31           2
 H histidine           2.5         10           1
 I isoleucine          6.8         27           2
 K lysine              6.0         24           2
 L leucine            10.0         40           2
 M methionine          2.8         11           1
 N asparagine          3.5         14           1
 P proline             7.8         31           3
 Q glutamine           3.5         14           2
 R arginine            6.2         25           2
 S serine              6.2         25           1
 T threonine           3.5         14           1
 V valine              6.8         27           2
 W tryptophan          0.5          2           1
 Y tyrosine            2.0          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase 2 
MAP2K1                0.787   mitogen-activated protein kinase kinase 1 
MAP2K5                0.294   mitogen-activated protein kinase kinase 5 isoform A ...
MAP2K5                0.274   mitogen-activated protein kinase kinase 5 isoform B [...
MAP2K6                0.234   mitogen-activated protein kinase kinase 6 
MAP2K3                0.231   mitogen-activated protein kinase kinase 3 isoform A ...
MAP2K3                0.231   mitogen-activated protein kinase kinase 3 isoform B ...
MAP2K4                0.229   mitogen-activated protein kinase kinase 4 
MAP2K7                0.228   mitogen-activated protein kinase kinase 7 
STK3                  0.186   serine/threonine kinase 3 
LOC100133591          0.179   PREDICTED: similar to MAP kinase 3c 
STK4                  0.174   serine/threonine kinase 4 
STK25                 0.157   serine/threonine kinase 25 
STK24                 0.154   serine/threonine kinase 24 isoform b 
STK24                 0.154   serine/threonine kinase 24 isoform a 
MST4                  0.153   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK10                 0.140   serine/threonine kinase 10 
LOC100133591          0.138   PREDICTED: similar to mitogen-activated protein kin...
MAP4K3                0.129   mitogen-activated protein kinase kinase kinase kinas...
MAP4K1                0.127   mitogen-activated protein kinase kinase kinase kina...
MAP4K1                0.127   mitogen-activated protein kinase kinase kinase kinase...
MAP4K5                0.123   mitogen-activated protein kinase kinase kinase kinas...
MAP4K5                0.123   mitogen-activated protein kinase kinase kinase kinas...
SLK                   0.123   serine/threonine kinase 2 
MINK1                 0.120   misshapen/NIK-related kinase isoform 4 
MINK1                 0.120   misshapen/NIK-related kinase isoform 2 
MINK1                 0.120   misshapen/NIK-related kinase isoform 3 
MINK1                 0.120   misshapen/NIK-related kinase isoform 1 
PAK2                  0.118   p21-activated kinase 2 
MAP4K2                0.118   mitogen-activated protein kinase kinase kinase kinas...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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