Guide to the Human Genome
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Name: MAP2K1 Sequence: fasta or formatted (393aa) NCBI GI: 5579478
Description:

mitogen-activated protein kinase kinase 1

Referenced in:

MAP Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         24           2
 C cysteine            1.5          6           1
 D aspartate           5.1         20           3
 E glutamate           7.6         30           2
 F phenylalanine       3.6         14           1
 G glycine             7.9         31           2
 H histidine           2.3          9           1
 I isoleucine          6.4         25           2
 K lysine              7.1         28           3
 L leucine             9.7         38           2
 M methionine          3.3         13           1
 N asparagine          3.3         13           1
 P proline             7.4         29           3
 Q glutamine           4.3         17           2
 R arginine            4.6         18           1
 S serine              7.6         30           2
 T threonine           3.1         12           1
 V valine              6.4         25           2
 W tryptophan          0.5          2           1
 Y tyrosine            2.3          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase 1 
MAP2K2                0.800   mitogen-activated protein kinase kinase 2 
MAP2K5                0.311   mitogen-activated protein kinase kinase 5 isoform A ...
MAP2K5                0.289   mitogen-activated protein kinase kinase 5 isoform B [...
MAP2K6                0.252   mitogen-activated protein kinase kinase 6 
MAP2K3                0.241   mitogen-activated protein kinase kinase 3 isoform A ...
MAP2K3                0.241   mitogen-activated protein kinase kinase 3 isoform B ...
MAP2K7                0.237   mitogen-activated protein kinase kinase 7 
MAP2K4                0.229   mitogen-activated protein kinase kinase 4 
STK3                  0.201   serine/threonine kinase 3 
STK4                  0.191   serine/threonine kinase 4 
LOC100133591          0.178   PREDICTED: similar to MAP kinase 3c 
STK25                 0.170   serine/threonine kinase 25 
STK24                 0.169   serine/threonine kinase 24 isoform b 
STK24                 0.169   serine/threonine kinase 24 isoform a 
MST4                  0.167   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK10                 0.156   serine/threonine kinase 10 
MAP4K3                0.140   mitogen-activated protein kinase kinase kinase kinas...
LOC100133591          0.139   PREDICTED: similar to mitogen-activated protein kin...
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 8 
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 7 
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 6 
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 5 
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 4 
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 3 
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 2 
TNIK                  0.136   TRAF2 and NCK interacting kinase isoform 1 
MAP4K1                0.135   mitogen-activated protein kinase kinase kinase kina...
MAP4K1                0.135   mitogen-activated protein kinase kinase kinase kinase...
MAP4K5                0.132   mitogen-activated protein kinase kinase kinase kinas...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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