Guide to the Human Genome
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Name: MAP2K4 Sequence: fasta or formatted (399aa) NCBI GI: 4506889
Description:

mitogen-activated protein kinase kinase 4

Referenced in:

MAP Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.3         21           2
 C cysteine            2.0          8           1
 D aspartate           6.0         24           2
 E glutamate           5.5         22           2
 F phenylalanine       3.8         15           1
 G glycine             7.8         31           4
 H histidine           2.0          8           1
 I isoleucine          5.8         23           2
 K lysine              7.3         29           1
 L leucine             8.3         33           2
 M methionine          3.0         12           1
 N asparagine          3.5         14           1
 P proline             7.5         30           2
 Q glutamine           3.3         13           1
 R arginine            5.0         20           1
 S serine              9.3         37           2
 T threonine           4.0         16           1
 V valine              6.3         25           2
 W tryptophan          1.0          4           1
 Y tyrosine            3.5         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase 4 
MAP2K6                0.417   mitogen-activated protein kinase kinase 6 
MAP2K3                0.401   mitogen-activated protein kinase kinase 3 isoform B ...
MAP2K3                0.398   mitogen-activated protein kinase kinase 3 isoform A ...
MAP2K7                0.339   mitogen-activated protein kinase kinase 7 
LOC100133591          0.298   PREDICTED: similar to MAP kinase 3c 
LOC100133591          0.238   PREDICTED: similar to mitogen-activated protein kin...
MAP2K5                0.228   mitogen-activated protein kinase kinase 5 isoform A ...
MAP2K2                0.225   mitogen-activated protein kinase kinase 2 
MAP2K1                0.221   mitogen-activated protein kinase kinase 1 
MAP2K5                0.206   mitogen-activated protein kinase kinase 5 isoform B [...
STK3                  0.167   serine/threonine kinase 3 
STK4                  0.164   serine/threonine kinase 4 
STK24                 0.155   serine/threonine kinase 24 isoform a 
STK24                 0.155   serine/threonine kinase 24 isoform b 
STK25                 0.153   serine/threonine kinase 25 
MST4                  0.149   serine/threonine protein kinase MST4 isoform 1 [Homo...
SLK                   0.147   serine/threonine kinase 2 
MYO3A                 0.143   myosin IIIA 
STK10                 0.142   serine/threonine kinase 10 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 8 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 7 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 6 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 5 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 4 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 3 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 2 
TNIK                  0.135   TRAF2 and NCK interacting kinase isoform 1 
MYO3B                 0.135   myosin IIIB isoform 1 
MYO3B                 0.135   myosin IIIB isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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