Guide to the Human Genome
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Search of human proteins with 13470094

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13470094 apolipoprotein L5 [Homo sapiens]
         (433 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13470094 apolipoprotein L5 [Homo sapiens]                          875   0.0  
gi|13449281 apolipoprotein L6 [Homo sapiens]                          188   7e-48
gi|13562090 apolipoprotein L2 [Homo sapiens]                          136   4e-32
gi|22035653 apolipoprotein L2 [Homo sapiens]                          136   4e-32
gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]                135   7e-32
gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens]     110   3e-24
gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens]     110   3e-24
gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens]      110   3e-24
gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens]      110   3e-24
gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]                102   9e-22
gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]      102   9e-22
gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens]                100   3e-21
gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens]                100   3e-21
gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Hom...    42   0.001
gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Hom...    42   0.001
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                 39   0.012
gi|91984775 regulator of telomere elongation helicase 1 isoform ...    35   0.13 
gi|7706541 regulator of telomere elongation helicase 1 isoform 1...    35   0.13 
gi|119943102 CREB binding protein isoform b [Homo sapiens]             35   0.17 
gi|119943104 CREB binding protein isoform a [Homo sapiens]             35   0.17 
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             34   0.23 
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ...    34   0.30 
gi|21071077 dishevelled-associated activator of morphogenesis 1 ...    33   0.50 
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    32   1.1  
gi|114688046 TBC1 domain family, member 4 [Homo sapiens]               32   1.1  
gi|239751877 PREDICTED: hypothetical protein XP_002348035 [Homo ...    31   1.9  
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    31   1.9  
gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens]        31   1.9  
gi|112382372 guanylate binding protein 3 [Homo sapiens]                31   1.9  
gi|190570174 cytochrome P450, family 21, subfamily A, polypeptid...    31   2.5  

>gi|13470094 apolipoprotein L5 [Homo sapiens]
          Length = 433

 Score =  875 bits (2261), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 1   MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKIN 60
           MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKIN
Sbjct: 1   MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKIN 60

Query: 61  NLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKEL 120
           NLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKEL
Sbjct: 61  NLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKEL 120

Query: 121 NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA 180
           NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA
Sbjct: 121 NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA 180

Query: 181 AITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGI 240
           AITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGI
Sbjct: 181 AITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGI 240

Query: 241 KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAG 300
           KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAG
Sbjct: 241 KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAG 300

Query: 301 FLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSS 360
           FLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSS
Sbjct: 301 FLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSS 360

Query: 361 SRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP 420
           SRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP
Sbjct: 361 SRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP 420

Query: 421 ARKGRQAPGRHRQ 433
           ARKGRQAPGRHRQ
Sbjct: 421 ARKGRQAPGRHRQ 433


>gi|13449281 apolipoprotein L6 [Homo sapiens]
          Length = 343

 Score =  188 bits (478), Expect = 7e-48
 Identities = 112/284 (39%), Positives = 165/284 (58%), Gaps = 7/284 (2%)

Query: 85  CDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSS 144
           C+   + DG+LS EEK+FL  FP  K +L+ NI +L  LAD +D TH+  TK ++VA+S+
Sbjct: 25  CEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATST 84

Query: 145 GAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASR 204
             +SGVM++LGLALAP T GGSL+LS  G GL  AA +T+IV+  LE   N  A+ +A  
Sbjct: 85  AVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAED 144

Query: 205 LGPLTTSHEAFGGINWSE-IEAAGFCVNKCVKAIQ-GIKDLHAYQMAKSNSGFMAMVKNF 262
           + P     +       ++ + AAG  +      ++   K++ A+   ++N       K  
Sbjct: 145 ILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLANATKRL 204

Query: 263 VAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGAR 322
           +    +   +   VQ+AF GTTLAMT  A V+G   + F L  D+++  + WKHL++GAR
Sbjct: 205 LTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGAR 264

Query: 323 TETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAV 366
           T+ AEELRA A +LE++L  LTQ ++ L QK       SR R V
Sbjct: 265 TKFAEELRAKALELERKLTELTQLYKSLQQKV-----RSRARGV 303


>gi|13562090 apolipoprotein L2 [Homo sapiens]
          Length = 337

 Score =  136 bits (342), Expect = 4e-32
 Identities = 97/283 (34%), Positives = 150/283 (53%), Gaps = 15/283 (5%)

Query: 73  MLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHE 132
           + S+ + ++  R DKD        +  + FL  FP  K ELE +I++L  LA++V+  H 
Sbjct: 59  LASHMVMKDKNRHDKDQ-------QHRQWFLKEFPRLKRELEDHIRKLRALAEEVEQVHR 111

Query: 133 LLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLEN 192
             T  ++V++S G  SG++ +LGL LAP T G S +L  TG GLGAAAA+  I  +V+E 
Sbjct: 112 GTTIANVVSNSVGTTSGILTLLGLGLAPFTEGISFVLLDTGMGLGAAAAVAGITCSVVEL 171

Query: 193 RSNSAARDKASRLGPLTTS----HEAFGGINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQ 247
            +   AR +A  L    T+     + F G N   +      V+   +  QGI +++ A +
Sbjct: 172 VNKLRARAQARNLDQSGTNVAKVMKEFVGGNTPNVLT---LVDNWYQVTQGIGRNIRAIR 228

Query: 248 MAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDM 307
            A++N    A          I       V+R  EG   AM+ G  ++GAA  G LL+ D+
Sbjct: 229 RARANPQLGAYAPPPHIIGRISAEGGEQVERVVEGPAQAMSRGTMIVGAATGGILLLLDV 288

Query: 308 SSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHL 350
            S     KHL +GA++E+AEEL+  A++LE +L+ LT+ H  L
Sbjct: 289 VSLAYESKHLLEGAKSESAEELKKRAQELEGKLNFLTKIHEML 331


>gi|22035653 apolipoprotein L2 [Homo sapiens]
          Length = 337

 Score =  136 bits (342), Expect = 4e-32
 Identities = 97/283 (34%), Positives = 150/283 (53%), Gaps = 15/283 (5%)

Query: 73  MLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHE 132
           + S+ + ++  R DKD        +  + FL  FP  K ELE +I++L  LA++V+  H 
Sbjct: 59  LASHMVMKDKNRHDKDQ-------QHRQWFLKEFPRLKRELEDHIRKLRALAEEVEQVHR 111

Query: 133 LLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLEN 192
             T  ++V++S G  SG++ +LGL LAP T G S +L  TG GLGAAAA+  I  +V+E 
Sbjct: 112 GTTIANVVSNSVGTTSGILTLLGLGLAPFTEGISFVLLDTGMGLGAAAAVAGITCSVVEL 171

Query: 193 RSNSAARDKASRLGPLTTS----HEAFGGINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQ 247
            +   AR +A  L    T+     + F G N   +      V+   +  QGI +++ A +
Sbjct: 172 VNKLRARAQARNLDQSGTNVAKVMKEFVGGNTPNVLT---LVDNWYQVTQGIGRNIRAIR 228

Query: 248 MAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDM 307
            A++N    A          I       V+R  EG   AM+ G  ++GAA  G LL+ D+
Sbjct: 229 RARANPQLGAYAPPPHIIGRISAEGGEQVERVVEGPAQAMSRGTMIVGAATGGILLLLDV 288

Query: 308 SSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHL 350
            S     KHL +GA++E+AEEL+  A++LE +L+ LT+ H  L
Sbjct: 289 VSLAYESKHLLEGAKSESAEELKKRAQELEGKLNFLTKIHEML 331


>gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]
          Length = 402

 Score =  135 bits (340), Expect = 7e-32
 Identities = 87/251 (34%), Positives = 143/251 (56%), Gaps = 8/251 (3%)

Query: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161
           FL  FP  K +++++I++L  LA+ ++  H   T +++V+SS+GA SG+M++ GL LAP 
Sbjct: 152 FLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGLVLAPF 211

Query: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGINW 220
           TAG SL L+A G GLGAA+A+T I T+++E+   S+A  +ASRL   +    + F  +  
Sbjct: 212 TAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFKEVMR 271

Query: 221 SEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRA 279
                    +N   +A Q I  ++ A + A+      A  +  V    I   +    +R 
Sbjct: 272 DITPNLLSLLNNYYEATQTIGSEIRAIRQAR------ARARLPVTTWRISAGSGGQAERT 325

Query: 280 FEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQE 339
             GTT A++ GA ++ A  +G  L  D+ + +   KHL +GA++ +AEELR  A++LE+ 
Sbjct: 326 IAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQELEEN 385

Query: 340 LDRLTQHHRHL 350
           L  LTQ ++ L
Sbjct: 386 LMELTQIYQRL 396


>gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens]
          Length = 380

 Score =  110 bits (274), Expect = 3e-24
 Identities = 84/260 (32%), Positives = 134/260 (51%), Gaps = 18/260 (6%)

Query: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161
           FL  FP  K ELE NI+ L  LAD V   H+  T  ++V+ S    SG++ ++G+ LAP 
Sbjct: 122 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 181

Query: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENR----SNSAARDKASR-LGPLTTSHEAFG 216
           T GGSL+L   G  LG  AA+T I ++ ++      + + A D   + L  L    E  G
Sbjct: 182 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 241

Query: 217 GINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKR-----HIPF 270
               + +  AG       +  +GI KD+ A + A++N   +  V +  A R      I  
Sbjct: 242 ENISNFLSLAG----NTYQLTRGIGKDIRALRRARAN---LQSVPHASASRPRVTEPISA 294

Query: 271 WTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELR 330
            +   V+R  E + L M+ G  +   A   F L+ D+   +   KHL +GA++ETAEEL+
Sbjct: 295 ESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELK 354

Query: 331 ALAKKLEQELDRLTQHHRHL 350
            +A++LE++L+ L  +++ L
Sbjct: 355 KVAQELEEKLNILNNNYKIL 374


>gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens]
          Length = 398

 Score =  110 bits (274), Expect = 3e-24
 Identities = 84/260 (32%), Positives = 134/260 (51%), Gaps = 18/260 (6%)

Query: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161
           FL  FP  K ELE NI+ L  LAD V   H+  T  ++V+ S    SG++ ++G+ LAP 
Sbjct: 140 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 199

Query: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENR----SNSAARDKASR-LGPLTTSHEAFG 216
           T GGSL+L   G  LG  AA+T I ++ ++      + + A D   + L  L    E  G
Sbjct: 200 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 259

Query: 217 GINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKR-----HIPF 270
               + +  AG       +  +GI KD+ A + A++N   +  V +  A R      I  
Sbjct: 260 ENISNFLSLAG----NTYQLTRGIGKDIRALRRARAN---LQSVPHASASRPRVTEPISA 312

Query: 271 WTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELR 330
            +   V+R  E + L M+ G  +   A   F L+ D+   +   KHL +GA++ETAEEL+
Sbjct: 313 ESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELK 372

Query: 331 ALAKKLEQELDRLTQHHRHL 350
            +A++LE++L+ L  +++ L
Sbjct: 373 KVAQELEEKLNILNNNYKIL 392


>gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens]
          Length = 414

 Score =  110 bits (274), Expect = 3e-24
 Identities = 84/260 (32%), Positives = 134/260 (51%), Gaps = 18/260 (6%)

Query: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161
           FL  FP  K ELE NI+ L  LAD V   H+  T  ++V+ S    SG++ ++G+ LAP 
Sbjct: 156 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 215

Query: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENR----SNSAARDKASR-LGPLTTSHEAFG 216
           T GGSL+L   G  LG  AA+T I ++ ++      + + A D   + L  L    E  G
Sbjct: 216 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 275

Query: 217 GINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKR-----HIPF 270
               + +  AG       +  +GI KD+ A + A++N   +  V +  A R      I  
Sbjct: 276 ENISNFLSLAG----NTYQLTRGIGKDIRALRRARAN---LQSVPHASASRPRVTEPISA 328

Query: 271 WTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELR 330
            +   V+R  E + L M+ G  +   A   F L+ D+   +   KHL +GA++ETAEEL+
Sbjct: 329 ESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELK 388

Query: 331 ALAKKLEQELDRLTQHHRHL 350
            +A++LE++L+ L  +++ L
Sbjct: 389 KVAQELEEKLNILNNNYKIL 408


>gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens]
          Length = 398

 Score =  110 bits (274), Expect = 3e-24
 Identities = 84/260 (32%), Positives = 134/260 (51%), Gaps = 18/260 (6%)

Query: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161
           FL  FP  K ELE NI+ L  LAD V   H+  T  ++V+ S    SG++ ++G+ LAP 
Sbjct: 140 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 199

Query: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENR----SNSAARDKASR-LGPLTTSHEAFG 216
           T GGSL+L   G  LG  AA+T I ++ ++      + + A D   + L  L    E  G
Sbjct: 200 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 259

Query: 217 GINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKR-----HIPF 270
               + +  AG       +  +GI KD+ A + A++N   +  V +  A R      I  
Sbjct: 260 ENISNFLSLAG----NTYQLTRGIGKDIRALRRARAN---LQSVPHASASRPRVTEPISA 312

Query: 271 WTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELR 330
            +   V+R  E + L M+ G  +   A   F L+ D+   +   KHL +GA++ETAEEL+
Sbjct: 313 ESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELK 372

Query: 331 ALAKKLEQELDRLTQHHRHL 350
            +A++LE++L+ L  +++ L
Sbjct: 373 KVAQELEEKLNILNNNYKIL 392


>gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]
          Length = 348

 Score =  102 bits (253), Expect = 9e-22
 Identities = 73/253 (28%), Positives = 134/253 (52%), Gaps = 16/253 (6%)

Query: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161
           FL  FP  +++++++I+ L  +A++++  H      ++V+ S+G    +++++G+ LAP 
Sbjct: 105 FLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSGSTG----ILSVIGVMLAPF 160

Query: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGI-- 218
           TAG SL ++A G GLG A+A   I ++++EN    +A   ASRL   +T   EA   I  
Sbjct: 161 TAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILR 220

Query: 219 -NWSEIEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ 277
                + +     ++  K I    D+H  + +K+  G     +  +A R++P      + 
Sbjct: 221 DITPNVLSFALDFDEATKMI--ANDVHTLRRSKATVG-----RPLIAWRYVPINVVETL- 272

Query: 278 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE 337
           R     T  +   A  +G A +G L++ D+ + +Q    L  GA++E+AE LR  A++LE
Sbjct: 273 RTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELE 332

Query: 338 QELDRLTQHHRHL 350
           + L+ LT  H+ L
Sbjct: 333 ENLNELTHIHQSL 345


>gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]
          Length = 351

 Score =  102 bits (253), Expect = 9e-22
 Identities = 73/253 (28%), Positives = 134/253 (52%), Gaps = 16/253 (6%)

Query: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161
           FL  FP  +++++++I+ L  +A++++  H      ++V+ S+G    +++++G+ LAP 
Sbjct: 108 FLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSGSTG----ILSVIGVMLAPF 163

Query: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGI-- 218
           TAG SL ++A G GLG A+A   I ++++EN    +A   ASRL   +T   EA   I  
Sbjct: 164 TAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILR 223

Query: 219 -NWSEIEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ 277
                + +     ++  K I    D+H  + +K+  G     +  +A R++P      + 
Sbjct: 224 DITPNVLSFALDFDEATKMI--ANDVHTLRRSKATVG-----RPLIAWRYVPINVVETL- 275

Query: 278 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE 337
           R     T  +   A  +G A +G L++ D+ + +Q    L  GA++E+AE LR  A++LE
Sbjct: 276 RTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELE 335

Query: 338 QELDRLTQHHRHL 350
           + L+ LT  H+ L
Sbjct: 336 ENLNELTHIHQSL 348


>gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens]
          Length = 202

 Score =  100 bits (248), Expect = 3e-21
 Identities = 69/202 (34%), Positives = 109/202 (53%), Gaps = 8/202 (3%)

Query: 151 MNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTT 210
           M++ GL LAP TAG SL L+A G GLGAA+A+T I T+++E+   S+A  +ASRL   + 
Sbjct: 1   MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60

Query: 211 SH-EAFGGINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHI 268
              + F  +           +N   +A Q I  ++ A + A+      A  +  V    I
Sbjct: 61  DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQAR------ARARLPVTTWRI 114

Query: 269 PFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEE 328
              +    +R   GTT A++ GA ++ A  +G  L  D+ + +   KHL +GA++ +AEE
Sbjct: 115 SAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEE 174

Query: 329 LRALAKKLEQELDRLTQHHRHL 350
           LR  A++LE+ L  LTQ ++ L
Sbjct: 175 LRRQAQELEENLMELTQIYQRL 196


>gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens]
          Length = 202

 Score =  100 bits (248), Expect = 3e-21
 Identities = 69/202 (34%), Positives = 109/202 (53%), Gaps = 8/202 (3%)

Query: 151 MNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTT 210
           M++ GL LAP TAG SL L+A G GLGAA+A+T I T+++E+   S+A  +ASRL   + 
Sbjct: 1   MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60

Query: 211 SH-EAFGGINWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHI 268
              + F  +           +N   +A Q I  ++ A + A+      A  +  V    I
Sbjct: 61  DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQAR------ARARLPVTTWRI 114

Query: 269 PFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEE 328
              +    +R   GTT A++ GA ++ A  +G  L  D+ + +   KHL +GA++ +AEE
Sbjct: 115 SAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEE 174

Query: 329 LRALAKKLEQELDRLTQHHRHL 350
           LR  A++LE+ L  LTQ ++ L
Sbjct: 175 LRRQAQELEENLMELTQIYQRL 196


>gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 279

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 4/62 (6%)

Query: 132 ELLTKTSLVASSSG----AVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVT 187
           E L + SLVA+ +G    A   +  I+GL+L+PVT G SL++SA G G+  A     I +
Sbjct: 77  ERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLVSAVGLGVATAGGAVTITS 136

Query: 188 NV 189
           ++
Sbjct: 137 DL 138


>gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 248

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 4/62 (6%)

Query: 132 ELLTKTSLVASSSG----AVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVT 187
           E L + SLVA+ +G    A   +  I+GL+L+PVT G SL++SA G G+  A     I +
Sbjct: 46  ERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLVSAVGLGVATAGGAVTITS 105

Query: 188 NV 189
           ++
Sbjct: 106 DL 107


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 36/136 (26%), Positives = 60/136 (44%), Gaps = 14/136 (10%)

Query: 302  LLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSS 361
            L  K +   + SW+H+     TE A  L+  A+   ++ + LT+ H+      +Q  SS 
Sbjct: 1270 LKAKALEKTVASWQHMA----TEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSV 1325

Query: 362  RGRAVR--GSRVVKPEGSRSPLPWPVVEHQPRL-------GPGVALRTPKRTVSAPRMLG 412
            +   V   G+R +  +     L +P  + Q  L          +   T K+T  A RMLG
Sbjct: 1326 QAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLG 1385

Query: 413  H-QPAPPAPARKGRQA 427
            +  P   +  +KGR+A
Sbjct: 1386 NAAPLSSSAKKKGREA 1401


>gi|91984775 regulator of telomere elongation helicase 1 isoform 2
            [Homo sapiens]
          Length = 1300

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 349  HLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQ-PRLGPGVALRTPKRTVSA 407
            H  Q+ SQTC+   GR   G     P+  R  +P PV+ H+ P+ GP  + +T K     
Sbjct: 1123 HHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVP-PVLTHRAPQPGPSRSEKTGKTQSKI 1181

Query: 408  PRMLGHQPA 416
               L  +PA
Sbjct: 1182 SSFLRQRPA 1190


>gi|7706541 regulator of telomere elongation helicase 1 isoform 1
            [Homo sapiens]
          Length = 1219

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 349  HLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQ-PRLGPGVALRTPKRTVSA 407
            H  Q+ SQTC+   GR   G     P+  R  +P PV+ H+ P+ GP  + +T K     
Sbjct: 1123 HHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVP-PVLTHRAPQPGPSRSEKTGKTQSKI 1181

Query: 408  PRMLGHQPA 416
               L  +PA
Sbjct: 1182 SSFLRQRPA 1190


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 344  TQHHRHLPQKA--SQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTP 401
            T + R++PQ++  S T +       + S    P+    P P PV    P   P VA   P
Sbjct: 1833 TMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPV-SMSPAGFPSVARTQP 1891

Query: 402  KRTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ 433
              TVS  +     PAPP PA+    A    RQ
Sbjct: 1892 PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQ 1923


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 344  TQHHRHLPQKA--SQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTP 401
            T + R++PQ++  S T +       + S    P+    P P PV    P   P VA   P
Sbjct: 1871 TMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPV-SMSPAGFPSVARTQP 1929

Query: 402  KRTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ 433
              TVS  +     PAPP PA+    A    RQ
Sbjct: 1930 PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQ 1961


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 34.3 bits (77), Expect = 0.23
 Identities = 34/115 (29%), Positives = 47/115 (40%), Gaps = 12/115 (10%)

Query: 324 ETAEELRALAKKLEQELDRLTQHHRHLPQ-----KASQTCSSSRGRAVRGSRVVKPE--- 375
           ET E+LR L ++  QE D L     +LP      +        + R  RG    +P    
Sbjct: 578 ETMEQLRNLPQQCMQE-DFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRL 636

Query: 376 -GSRSPLPWPVVEHQPRLGPGVALRT-PKRTVSAPRMLGHQPAPPAPARKGRQAP 428
            GSR+ +       QP LGP  +L + P       R  G  P+PP P R+    P
Sbjct: 637 HGSRA-IHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVRRASAGP 690


>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
           [Homo sapiens]
          Length = 424

 Score = 33.9 bits (76), Expect = 0.30
 Identities = 33/111 (29%), Positives = 41/111 (36%), Gaps = 11/111 (9%)

Query: 334 KKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVK---------PEGSRSPLPWP 384
           K L   + +LT+    LP  A     SS  R V  SR  K         P G  +  PWP
Sbjct: 216 KHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPWP 275

Query: 385 VVEHQPRLGPGVALRTPKRTVSAPRM-LGHQPAP-PAPARKGRQAPGRHRQ 433
           +    P   P  +   P   V      +G Q  P PA A+ G Q   R  Q
Sbjct: 276 IWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQ 326


>gi|21071077 dishevelled-associated activator of morphogenesis 1
           [Homo sapiens]
          Length = 1078

 Score = 33.1 bits (74), Expect = 0.50
 Identities = 29/114 (25%), Positives = 44/114 (38%), Gaps = 6/114 (5%)

Query: 315 KHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKP 374
           K  E  A+T+  EE+     K++++L++ T  H+ + Q+ +   +     + R      P
Sbjct: 469 KERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVCASIP 528

Query: 375 EGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAPARKGRQAP 428
            G   P P       P   PG  L  P      P   G  P PP P   G   P
Sbjct: 529 GG---PSPGAPGGPFPSSVPGSLLPPPP---PPPLPGGMLPPPPPPLPPGGPPP 576


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 7/93 (7%)

Query: 342 RLTQHHRHLPQKASQTCSSSR---GRAVRGSRVVKPEGSRSPLPWPVVEHQPRLG---PG 395
           ++T+ HR  P+K S++ SSS+       + S+    +     LP       P+     P 
Sbjct: 196 KVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPK 255

Query: 396 VALRTPKRTVSAPRMLGHQPAPPAPARKGRQAP 428
           +AL+  K   ++P+  G  P PP P R   + P
Sbjct: 256 MALKETKLESTSPKG-GPPPPPPPPPRASSKRP 287


>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
          Length = 1298

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 6/61 (9%)

Query: 63   MSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYF------PLHKFELEQN 116
            +S + S E  ++    FE ++   K+++PD N SE EK+    F       LH +E+E +
Sbjct: 1121 LSLLSSQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDISKQLHAYEVEYH 1180

Query: 117  I 117
            +
Sbjct: 1181 V 1181


>gi|239751877 PREDICTED: hypothetical protein XP_002348035 [Homo
           sapiens]
          Length = 944

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 8/110 (7%)

Query: 290 GAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRH 349
           G W++G    G  L       L   + +  GAR    E+L A A+ L   +  + Q HR 
Sbjct: 633 GRWLVGLGRLGGCL-------LGLGRRIGPGARLVLQEQLLA-AESLLAAIAAVHQLHRG 684

Query: 350 LPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALR 399
           L ++  +     RGR  RG R  +  G   PL   V        PG+  R
Sbjct: 685 LRRRQKELRHHGRGRGRRGGRRGRAVGLEVPLQVGVAHEDLAGLPGLGGR 734


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 9/94 (9%)

Query: 332 LAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVV--KPEGSRSPLPWPVVEHQ 389
           L   LE +L     HH HL  +  +  +++ G    G+ VV   P G+    P    E  
Sbjct: 25  LVGSLESQLAASAAHHHHLAPRTPEVRAAAAG--ALGNHVVSGSPAGAAGAGPAAPAEG- 81

Query: 390 PRLGPGVALRTPKRTVSAPRMLGHQ-PAPPAPAR 422
               PG A   P    + P   G Q P PP+P R
Sbjct: 82  ---APGAAPEPPPAGRARPGGGGPQRPGPPSPRR 112


>gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens]
          Length = 356

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 328 ELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVE 387
           E RA  ++L Q   R  +H     ++ ++T ++S GR  RG    +  G R+  P P+V 
Sbjct: 217 EERARKRRL-QAARRAEEHKNQTIERLTKTAATS-GRGGRGGARGERRGGRAAAPAPMVR 274

Query: 388 HQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP 420
           +      G  L  P   V AP  +  +P+P  P
Sbjct: 275 YCSG-AQGSTLSFPP-GVPAPTAVSQRPSPSGP 305


>gi|112382372 guanylate binding protein 3 [Homo sapiens]
          Length = 595

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 49  SLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFP 107
           +L  L  S  + N M T++      L Y++ E   R    S PD N +E+   F+S+FP
Sbjct: 117 TLAVLLSSTLVYNSMGTINQQAMDQL-YYVTELTHRIRSKSSPDENENEDSADFVSFFP 174


>gi|190570174 cytochrome P450, family 21, subfamily A, polypeptide 2
           isoform b [Homo sapiens]
          Length = 465

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 19/68 (27%), Positives = 27/68 (39%)

Query: 346 HHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTV 405
           HH  + Q+  +      G     SRV   + +R PL    +    RL P V L  P RT 
Sbjct: 280 HHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTT 339

Query: 406 SAPRMLGH 413
               + G+
Sbjct: 340 RPSSISGY 347


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,584,683
Number of Sequences: 37866
Number of extensions: 861453
Number of successful extensions: 3907
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 3829
Number of HSP's gapped (non-prelim): 164
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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