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Search of human proteins with 61097912
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61097912 nucleolar protein with MIF4G domain 1 [Homo
sapiens]
(860 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens] 1687 0.0
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s... 129 1e-29
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 64 8e-10
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 62 3e-09
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 60 7e-09
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 59 1e-08
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 59 1e-08
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 59 2e-08
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 59 2e-08
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 59 3e-08
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 58 3e-08
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 58 3e-08
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 58 4e-08
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 58 4e-08
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 58 4e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 6e-08
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 57 6e-08
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 57 6e-08
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 57 7e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 57 7e-08
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 57 1e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 57 1e-07
gi|55956788 nucleolin [Homo sapiens] 56 1e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 1e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 56 1e-07
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 56 1e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 55 3e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 55 4e-07
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 55 4e-07
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 54 6e-07
>gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens]
Length = 860
Score = 1687 bits (4369), Expect = 0.0
Identities = 860/860 (100%), Positives = 860/860 (100%)
Query: 1 MAASRSAGEAGPGGSQGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGE 60
MAASRSAGEAGPGGSQGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGE
Sbjct: 1 MAASRSAGEAGPGGSQGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGE 60
Query: 61 APGGCEGRGAPVSFRPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEAS 120
APGGCEGRGAPVSFRPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEAS
Sbjct: 61 APGGCEGRGAPVSFRPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEAS 120
Query: 121 GHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANE 180
GHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANE
Sbjct: 121 GHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANE 180
Query: 181 EEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEE 240
EEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEE
Sbjct: 181 EEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEE 240
Query: 241 DAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQ 300
DAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQ
Sbjct: 241 DAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQ 300
Query: 301 EKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELER 360
EKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELER
Sbjct: 301 EKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELER 360
Query: 361 LKKHVKGLLNRLSEPNMASISGQLEELYMAHSRKDMNDTLTSALMGACVTASAMPSRLMM 420
LKKHVKGLLNRLSEPNMASISGQLEELYMAHSRKDMNDTLTSALMGACVTASAMPSRLMM
Sbjct: 361 LKKHVKGLLNRLSEPNMASISGQLEELYMAHSRKDMNDTLTSALMGACVTASAMPSRLMM 420
Query: 421 EHVLLVSILHHTVGIEVGAHFLEAVVRKFDAIYKYGSEGKECDNLFTVIAHLYNFHVVQS 480
EHVLLVSILHHTVGIEVGAHFLEAVVRKFDAIYKYGSEGKECDNLFTVIAHLYNFHVVQS
Sbjct: 421 EHVLLVSILHHTVGIEVGAHFLEAVVRKFDAIYKYGSEGKECDNLFTVIAHLYNFHVVQS 480
Query: 481 LLIFDILKKLIGTFTEKDIELILLMLKNVGFSLRKDDALSLKELITEAQTKASGAGSEFQ 540
LLIFDILKKLIGTFTEKDIELILLMLKNVGFSLRKDDALSLKELITEAQTKASGAGSEFQ
Sbjct: 481 LLIFDILKKLIGTFTEKDIELILLMLKNVGFSLRKDDALSLKELITEAQTKASGAGSEFQ 540
Query: 541 DQTRIRFMLETMLALKNNDMRKIPGYDPEPVEKLRKLQRALVRNAGSGSETQLRVSWDSV 600
DQTRIRFMLETMLALKNNDMRKIPGYDPEPVEKLRKLQRALVRNAGSGSETQLRVSWDSV
Sbjct: 541 DQTRIRFMLETMLALKNNDMRKIPGYDPEPVEKLRKLQRALVRNAGSGSETQLRVSWDSV 600
Query: 601 LSAEQTGRWWIVGSAWSGAPMIDNSHHTHLQKQLVGTVSSKILELARKQRMNTDIRRNIF 660
LSAEQTGRWWIVGSAWSGAPMIDNSHHTHLQKQLVGTVSSKILELARKQRMNTDIRRNIF
Sbjct: 601 LSAEQTGRWWIVGSAWSGAPMIDNSHHTHLQKQLVGTVSSKILELARKQRMNTDIRRNIF 660
Query: 661 CTIMTSEDFLDAFEKLLKLGLKDQQEREIIHVLMDCCLQEKTYNPFYAFLASKFCEYERR 720
CTIMTSEDFLDAFEKLLKLGLKDQQEREIIHVLMDCCLQEKTYNPFYAFLASKFCEYERR
Sbjct: 661 CTIMTSEDFLDAFEKLLKLGLKDQQEREIIHVLMDCCLQEKTYNPFYAFLASKFCEYERR 720
Query: 721 FQMTFQFSIWDKFRDLENLPATNFSNLVHLVAHLLKTKSLSLSILKVVEFSELDKPRVRF 780
FQMTFQFSIWDKFRDLENLPATNFSNLVHLVAHLLKTKSLSLSILKVVEFSELDKPRVRF
Sbjct: 721 FQMTFQFSIWDKFRDLENLPATNFSNLVHLVAHLLKTKSLSLSILKVVEFSELDKPRVRF 780
Query: 781 LRKVLSILLMETEVEDLSLIFTRVSDNPKLGVLREGLKLFISHFLLKNAQAHRSADEANV 840
LRKVLSILLMETEVEDLSLIFTRVSDNPKLGVLREGLKLFISHFLLKNAQAHRSADEANV
Sbjct: 781 LRKVLSILLMETEVEDLSLIFTRVSDNPKLGVLREGLKLFISHFLLKNAQAHRSADEANV 840
Query: 841 LREKADLATKCLQGKASLRM 860
LREKADLATKCLQGKASLRM
Sbjct: 841 LREKADLATKCLQGKASLRM 860
>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
sapiens]
Length = 908
Score = 129 bits (324), Expect = 1e-29
Identities = 124/584 (21%), Positives = 241/584 (41%), Gaps = 78/584 (13%)
Query: 241 DAGQTLPESDLESDSQDESEEEEEG------------DVEKEKKAQEAEAQSEDDDEDTE 288
D + L S +D EE+E D E ++ + ++ E + D E
Sbjct: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
Query: 289 EEQGEEKEKGAQEKRRGKRV--RFAEDEEKSENSSEDGDITDKS-------LCGSGEKYI 339
+ + E++ + R+ R E +S++D T K L +G YI
Sbjct: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTGGAYI 134
Query: 340 PP-HVRQAEETVDFK-----KKEELERLKKHVKGLLNRLSEPNMASISGQLEELYMAHSR 393
PP +R +E + K ++ E LKK + GL+N+++ N++ I +L + + R
Sbjct: 135 PPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGR 194
Query: 394 KDMNDTLTSALMGACVTASAMPSRLMMEHVL--LVSILHHTVGIEVGAHFLEAVVRKFDA 451
++ ++ A SA P + HV LV+I++ ++G L+ ++ F
Sbjct: 195 GLLSRSVLQA-------QSASP---IFTHVYAALVAIINSKFP-QIGELILKRLILNFRK 243
Query: 452 IYKYGSEGKECDNLFTVIAHLYNFHVVQSLLIFDILKKLIGTFTEKDIELILLMLKNVGF 511
Y+ + + C +AHL N +V +L ++L L+ T+ +E+ + LK G
Sbjct: 244 GYRRNDK-QLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGL 302
Query: 512 SLRKDDALSLKELITEAQTKASGAGSEFQDQTRIRFMLETMLALKNNDMRKIP------- 564
L + + + + E + R+++M+E M A++ + + P
Sbjct: 303 KLTQVSPRGINAIFERLRNILH----ESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLD 358
Query: 565 ----------------GYDPEPVEKLRKLQRALVRNAGSGSETQLRVSWDSVLSAEQTGR 608
Y+PE V + K+ + N E + + +L T
Sbjct: 359 LVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMEN-----EEKYKAIKKEILDEGDTD- 412
Query: 609 WWIVGSAWSGAPMIDNSHHTHLQKQLVGTVSSKILELARKQRMNTDIRRNIFCTIMTSED 668
+ A + ++ K+ + + RR I+ I +S D
Sbjct: 413 ----SNTDQDAGSSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLD 468
Query: 669 FLDAFEKLLKLGLKDQQEREIIHVLMDCCLQEKTYNPFYAFLASKFCEYERRFQMTFQFS 728
F + KLLK+ + Q +E+ ++++DCC Q++TY F+ LA +FC ++ + +F+
Sbjct: 469 FEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGI 528
Query: 729 IWDKFRDLENLPATNFSNLVHLVAHLLKTKSLSLSILKVVEFSE 772
+++ + L N+ + AHLL T SL S+L+ ++ SE
Sbjct: 529 FKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSE 572
Score = 33.9 bits (76), Expect = 0.66
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 8/102 (7%)
Query: 200 KKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDES 259
+KDG P+ +GLD + + L D E+ + + +E++ + ++
Sbjct: 343 RKDGFKDHPIIL--EGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKA 400
Query: 260 EEEE---EGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKG 298
++E EGD + + +A S ++DE+ EEE+GEE E+G
Sbjct: 401 IKKEILDEGDTDSNT---DQDAGSSEEDEEEEEEEGEEDEEG 439
Score = 32.7 bits (73), Expect = 1.5
Identities = 16/49 (32%), Positives = 29/49 (59%)
Query: 227 KNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQE 275
+N Y + +E D G T +D ++ S +E EEEEE + E++++ Q+
Sbjct: 393 ENEEKYKAIKKEILDEGDTDSNTDQDAGSSEEDEEEEEEEGEEDEEGQK 441
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 6/102 (5%)
Query: 225 SGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDD- 283
S +S DSS + + + + S ESDS S + KK E D
Sbjct: 673 SASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDK 732
Query: 284 ----DEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSS 321
+ + +Q E +++ ++ R +R R +E + + +NSS
Sbjct: 733 LIRNQQTNDRKQKERRQEHGHQETRTERERRSE-KHRDQNSS 773
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 63.5 bits (153), Expect = 8e-10
Identities = 35/106 (33%), Positives = 60/106 (56%), Gaps = 10/106 (9%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
E+EED G+ E + E DE EE+EEGD E+E++ +E + ++D ED E+E+ EE+E
Sbjct: 101 EKEEDEGEEYSEDNDEPG--DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEE 158
Query: 297 KGAQEKRRGK--------RVRFAEDEEKSENSSEDGDITDKSLCGS 334
+ +E+ R +D EK +N++++ D D+ + S
Sbjct: 159 EEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKS 204
Score = 43.5 bits (101), Expect = 8e-04
Identities = 28/79 (35%), Positives = 44/79 (55%), Gaps = 10/79 (12%)
Query: 252 ESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFA 311
+S S DE ++ + + EK+ E E SED+DE +E+ EE E+G +E+
Sbjct: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED--EEDEEGDREEEE------- 133
Query: 312 EDEEKSENSSEDG-DITDK 329
E EE+ E+ EDG D+ D+
Sbjct: 134 EIEEEDEDDDEDGEDVEDE 152
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/79 (27%), Positives = 40/79 (50%)
Query: 245 TLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR 304
++ E D ++D E+EE+ E + E + E+D+E EE+ E +E+ +
Sbjct: 86 SVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDED 145
Query: 305 GKRVRFAEDEEKSENSSED 323
G+ V E+EE+ E E+
Sbjct: 146 GEDVEDEEEEEEEEEEEEE 164
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 61.6 bits (148), Expect = 3e-09
Identities = 79/316 (25%), Positives = 124/316 (39%), Gaps = 41/316 (12%)
Query: 55 ATSEGEAPGGCEGRG-APVSFRPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGR 113
A S GEA G EGRG G + ++ +EK K R G + PG G +
Sbjct: 641 AKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGR------GEMERPGEGEK 694
Query: 114 SGAEEASGHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKR 173
AE+ ++D EE+ + + +K R ++ + ++
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQG---HQKERNQEMEEGGEEEHGEGEEEEGDREEEEEK 751
Query: 174 ALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYD 233
E E E+ ER +RKK++ + G E G+ G
Sbjct: 752 EGEGKEEGEGEEVEG-EREKEEGERKKEERA----------------GKEEKGEEEG-DQ 793
Query: 234 SSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGE 293
GEEEE G+ + E + E E EEG E+E++ +E E + E+ + + EE +GE
Sbjct: 794 GEGEEEETEGR---GEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGE 850
Query: 294 EKE---KGAQEKRRGKRVR-------FAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHV 343
E+E KG +E G+ E+EE E+G+ + G GE
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEG 910
Query: 344 RQAEETVDFKKKEELE 359
EE + K +EE E
Sbjct: 911 EGEEEEGEGKGEEEGE 926
Score = 60.8 bits (146), Expect = 5e-09
Identities = 43/115 (37%), Positives = 61/115 (53%), Gaps = 13/115 (11%)
Query: 221 GALESGKNSGLYDSS-GEEEEDAGQT--LPESDLESDSQDESEEEEEGDVEKEKKAQEAE 277
G E G+ G + GE EE+ G+ E + E + + E EEEEEG+VE E + +E E
Sbjct: 972 GEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031
Query: 278 AQSEDDDEDTEEEQGEEKEK-GAQEKRRGKRVRFAEDEEK------SENSSEDGD 325
+ E E+ EE+GEE+EK G E+ R R E+E K EN +DG+
Sbjct: 1032 GEGE---EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGE 1083
Score = 59.3 bits (142), Expect = 1e-08
Identities = 46/146 (31%), Positives = 73/146 (50%), Gaps = 11/146 (7%)
Query: 221 GALESGKNSGLYDSS---GEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAE 277
G E G+ G + GEEEE G+ E + E + + EEEEG+ E E++ E E
Sbjct: 939 GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Query: 278 AQSEDDDEDTEEEQGEEKEKGAQE-KRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGE 336
+ E + E+ E +GEE+E+G E + G+ E E + E E+G+ +K G GE
Sbjct: 999 GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE---GEGEGEEEEGEEEGEEREKE--GEGE 1053
Query: 337 KYIPPHVRQAEETVDFKK--KEELER 360
+ + EE +++ +EE ER
Sbjct: 1054 ENRRNREEEEEEEGKYQETGEEENER 1079
Score = 58.2 bits (139), Expect = 3e-08
Identities = 68/265 (25%), Positives = 111/265 (41%), Gaps = 21/265 (7%)
Query: 75 RPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAP 134
R G + +KE +E+ H +K R + G E+ G G EE G R++ EE+
Sbjct: 705 RDGEEQEQKE--REQGH-QKERNQEMEEGGEEEHGEG-----EEEEGDREEEEEKE--GE 754
Query: 135 SRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLG 194
++ + R K + K A + EEE+ E R E+ G
Sbjct: 755 GKEEGEGEEVEGEREKEEGER---KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEG 811
Query: 195 LNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESD 254
+ + G + + G E G+ + GE EE+ G+ E + E
Sbjct: 812 ---GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE---EEEGEGEEEEGEGKGEEEGEEG 865
Query: 255 SQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTE-EEQGEEKEKGAQEKRRGKRVRFAED 313
+E EE EG+ E+E+ E E + E + E+ E E +GEE+ +G E+ G+ E
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925
Query: 314 EE-KSENSSEDGDITDKSLCGSGEK 337
EE + E E+G+ + G GE+
Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEE 950
Score = 58.2 bits (139), Expect = 3e-08
Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 12/143 (8%)
Query: 221 GALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEE---EEEGDV-EKEKKAQEA 276
G E G+ G + GE EE+ G+ E + E + ++E E EEEG+ E E + +E
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 277 EAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGE 336
E + ED + + EEE+GE +G +E+ G E EE+ E E+G+ + G GE
Sbjct: 938 EGEGEDGEGEGEEEEGE--WEGEEEEGEG------EGEEEGEGEGEEGEGEGEEEEGEGE 989
Query: 337 KYIPPHVRQAEETVDFKKKEELE 359
+ EE + +++ E E
Sbjct: 990 GEEEEGEEEGEEEGEGEEEGEGE 1012
Score = 57.8 bits (138), Expect = 4e-08
Identities = 36/118 (30%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
Query: 224 ESGKNSGLY-DSSGEEEEDAGQ-TLPESDLESDSQDESEEEEEGDVEKEKKAQ-EAEAQS 280
E G+ G + GEEEE G+ E + E + + E EEE EG+ E+E++ + E E +
Sbjct: 968 EEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG 1027
Query: 281 EDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKY 338
E+ + + EEE+GEE+ + +++ G+ R +EE+ E +++ GE+Y
Sbjct: 1028 EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEY 1085
Score = 56.2 bits (134), Expect = 1e-07
Identities = 48/152 (31%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 221 GALESGKNSGLYDSSGEEEEDAGQTLPESDL-ESDSQDESEEE-EEGDVEKEKKAQEAEA 278
G E G+ G D GE EE+ G+ E + E + ++E E E EEG+ E E++ E E
Sbjct: 932 GEEEEGEGEG-EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990
Query: 279 QSEDDDEDTEEE-QGEEKEKG-AQEKRRGKRVRFAEDEE-KSENSSEDGDITDKSLCGSG 335
+ E+ +E+ EEE +GEE+ +G +E+ G+ E EE + E E+G+ + G
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEG 1050
Query: 336 EKYIPPHVRQAEETVDFKKKEELERLKKHVKG 367
E R+ EE + K +E E + G
Sbjct: 1051 EGEENRRNREEEEEEEGKYQETGEEENERQDG 1082
Score = 55.8 bits (133), Expect = 2e-07
Identities = 52/178 (29%), Positives = 83/178 (46%), Gaps = 13/178 (7%)
Query: 221 GALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEK-EKKAQEAEAQ 279
G E G+ G + GE EE+ G+ E + E + EEE EG+ E E + +E E +
Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954
Query: 280 SEDDDEDTE---EEQGE-EKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSG 335
E ++E+ E EE+GE E E+G E + E+EE E E+G+ ++ G G
Sbjct: 955 WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE-GEG 1013
Query: 336 EK----YIPPHVRQAE---ETVDFKKKEELERLKKHVKGLLNRLSEPNMASISGQLEE 386
E+ + V E E + + +EE E +K +G NR + G+ +E
Sbjct: 1014 EEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Score = 48.1 bits (113), Expect = 3e-05
Identities = 43/149 (28%), Positives = 68/149 (45%), Gaps = 11/149 (7%)
Query: 220 LGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQ 279
+G E G G D + EE + + + E +D+ E E E EK+ E E
Sbjct: 644 VGEAEDGPE-GRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKE-- 700
Query: 280 SEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGD-ITDKSLCGSGEKY 338
E D EE++ +E+E+G Q K R + + +EE E E+GD ++ G G++
Sbjct: 701 -EWKKRDGEEQEQKEREQGHQ-KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE- 757
Query: 339 IPPHVRQAEETVDFKKKEELERLKKHVKG 367
+ EE ++KEE ER K+ G
Sbjct: 758 ----EGEGEEVEGEREKEEGERKKEERAG 782
Score = 39.3 bits (90), Expect = 0.016
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 224 ESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDD 283
E G+ G + GE E + E + E + +E EE E + E E+ + E + E++
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 284 -------DEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSE 322
+E+ E + GEE +K ++ K K + ++KS +++
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQ 1112
Score = 33.5 bits (75), Expect = 0.87
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 16/114 (14%)
Query: 236 GEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQ---------EAEAQSEDDDED 286
GE +D T E+D +SD +E E +EG K+ +Q EA S+++ E
Sbjct: 530 GELTQDTALT--END-DSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEI 586
Query: 287 TEEEQGEEKEKG----AQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGE 336
EE++G E KG QE + K + D+TDK+ G+
Sbjct: 587 PEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGK 640
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 60.5 bits (145), Expect = 7e-09
Identities = 28/67 (41%), Positives = 46/67 (68%)
Query: 252 ESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFA 311
E++ + E EEEE+ K KK +E E + E+++E+ EE++ EEKE+G + K++ KR R
Sbjct: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Query: 312 EDEEKSE 318
E+EEK +
Sbjct: 108 EEEEKKK 114
Score = 57.0 bits (136), Expect = 7e-08
Identities = 32/112 (28%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
Query: 252 ESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFA 311
E++ +E+EEEEE + ++++K +E + E + E E+ +EKE+ ++KR+ KR +
Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE-EEKKRKRKRKKKK 70
Query: 312 EDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELERLKK 363
E+EE+ E E+ + ++ G + R+ +E + KKK+ + KK
Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 43.9 bits (102), Expect = 6e-04
Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 269 KEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKR------VRFAEDEEKSENSSE 322
K+KK ++ E + ++ E+TEEE EEKE +EKR+ KR + E E++ E E
Sbjct: 1 KKKKKKKKETEETEETEETEEE--EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58
Query: 323 DGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELERLKKHVK 366
+ K E+ + EE + ++KEE R KK K
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 59.3 bits (142), Expect = 1e-08
Identities = 67/294 (22%), Positives = 121/294 (41%), Gaps = 25/294 (8%)
Query: 80 KSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPS 139
+S ++ ++K RK+ R++ T Q P + R + +R + +
Sbjct: 34 ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSAT 93
Query: 140 PPRKPRPSRVKA-KATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLNKR 198
+ R + K A K R S++A+ K N+ E +RK +
Sbjct: 94 EYKNEEYQRSERNKRLDADRKIRLSSSASREPYK------NQPEKTCVRKRD-------- 139
Query: 199 KKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGE--EEEDAGQTLPESDLESDSQ 256
++ S P R GL+ A S ++S +S E + + G + SD + ++
Sbjct: 140 PERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSS-GSSDEQGNNT 198
Query: 257 DESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEK 316
+ EE E DVE++++ +E + E+ DED EEE+ EE+E+ +E+ + E ++K
Sbjct: 199 ENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQK 258
Query: 317 SENSSEDGDITDKSLCGSGEKYIPPHVRQAEET--VDFKKKEELERLKKHVKGL 368
E + D + VR T D KKKE +K +G+
Sbjct: 259 EEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE-----RKRARGI 307
Score = 35.0 bits (79), Expect = 0.30
Identities = 25/107 (23%), Positives = 42/107 (39%), Gaps = 1/107 (0%)
Query: 224 ESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDD 283
E G + EEEE+ + E + E D +D+ EE + D E +E+ S D
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Query: 284 DEDTEEEQGEEKEKGAQEKRRGKRVR-FAEDEEKSENSSEDGDITDK 329
+ ++ +E++R + + D S S D T K
Sbjct: 283 GSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYADQTSK 329
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 59.3 bits (142), Expect = 1e-08
Identities = 67/294 (22%), Positives = 121/294 (41%), Gaps = 25/294 (8%)
Query: 80 KSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPS 139
+S ++ ++K RK+ R++ T Q P + R + +R + +
Sbjct: 34 ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSAT 93
Query: 140 PPRKPRPSRVKA-KATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLNKR 198
+ R + K A K R S++A+ K N+ E +RK +
Sbjct: 94 EYKNEEYQRSERNKRLDADRKIRLSSSASREPYK------NQPEKTCVRKRD-------- 139
Query: 199 KKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGE--EEEDAGQTLPESDLESDSQ 256
++ S P R GL+ A S ++S +S E + + G + SD + ++
Sbjct: 140 PERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSS-GSSDEQGNNT 198
Query: 257 DESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEK 316
+ EE E DVE++++ +E + E+ DED EEE+ EE+E+ +E+ + E ++K
Sbjct: 199 ENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQK 258
Query: 317 SENSSEDGDITDKSLCGSGEKYIPPHVRQAEET--VDFKKKEELERLKKHVKGL 368
E + D + VR T D KKKE +K +G+
Sbjct: 259 EEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE-----RKRARGI 307
Score = 36.2 bits (82), Expect = 0.13
Identities = 29/139 (20%), Positives = 57/139 (41%), Gaps = 12/139 (8%)
Query: 224 ESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDD 283
E G + EEEE+ + E + E D +D+ EE + D E +E+ S D
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Query: 284 DEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHV 343
+ ++ +E++R + + + ++SE S GS +K+
Sbjct: 283 GSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASE-------SYAGSEKKH----- 330
Query: 344 RQAEETVDFKKKEELERLK 362
+ +V +K++ +LK
Sbjct: 331 EKLSSSVRAVRKDQTSKLK 349
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 58.9 bits (141), Expect = 2e-08
Identities = 72/311 (23%), Positives = 125/311 (40%), Gaps = 42/311 (13%)
Query: 79 RKSRKELRKE--KRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSR 136
R+ R+E+ +E +R + +L+R E+ + E+ R+ E R R
Sbjct: 138 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 197
Query: 137 DPSPPRKPRPSRVKAKATAA---TAKTRPSAAATAAARKRALLAANEEEDREIRKLERCL 193
+ S + K A+ + RP R + + E+R++ + +
Sbjct: 198 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 257
Query: 194 GLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLES 253
++RK SS + ESG S + EEEE+ G T ES
Sbjct: 258 SDSERKTSSAESS---------------SAESGSGSEEEEEEEEEEEEEGSTSEES---- 298
Query: 254 DSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR-GKRVRFAE 312
E EEEEE + E+E + EA + +E +EEE E++E+ + RF
Sbjct: 299 ----EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 354
Query: 313 DEEKSENSSED-GDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELERLKKHVKG---- 367
D +SE + E+ G+ T +S + Y+P + + + K+EL + ++G
Sbjct: 355 DSGESEEAEEEVGEGTPQSSALTEGDYVP----DSPALLPIELKQELPKYLPALQGCRSV 410
Query: 368 ----LLNRLSE 374
LNR+ E
Sbjct: 411 EEFQCLNRIEE 421
Score = 34.7 bits (78), Expect = 0.39
Identities = 24/82 (29%), Positives = 37/82 (45%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+EE+ + L SD +D EE E D E + + + ED ED EE
Sbjct: 26 QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAI 85
Query: 297 KGAQEKRRGKRVRFAEDEEKSE 318
K Q+ R ++V +DE++ E
Sbjct: 86 KPPQQMSRKEKVHHRKDEKRKE 107
Score = 33.1 bits (74), Expect = 1.1
Identities = 29/138 (21%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
EE++ A + +++ S E + + E+K + E E E++ E+E
Sbjct: 127 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK---ERE 183
Query: 297 KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKE 356
+ A+E+R+ + R E + + + D +DK + P R+ E D +K
Sbjct: 184 RRAEERRKEREAR---REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240
Query: 357 ELERLKKHVKGLLNRLSE 374
+ E++++ + LL+ L +
Sbjct: 241 KEEKMEE--RDLLSDLQD 256
Score = 32.3 bits (72), Expect = 1.9
Identities = 27/129 (20%), Positives = 54/129 (41%), Gaps = 18/129 (13%)
Query: 238 EEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEK 297
+E+D+ + ++ + + E+EE+ ++++ K + DD D++ + EE E
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNS---------DDRDSKRDSLEEGEL 53
Query: 298 GAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
+ + + E+S ED D SL PP +E V +K E+
Sbjct: 54 ----RDHCMEITIRNSPYRREDSMEDRGEEDDSLA-----IKPPQQMSRKEKVHHRKDEK 104
Query: 358 LERLKKHVK 366
+ KH +
Sbjct: 105 RKEKWKHAR 113
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 58.9 bits (141), Expect = 2e-08
Identities = 72/311 (23%), Positives = 125/311 (40%), Gaps = 42/311 (13%)
Query: 79 RKSRKELRKE--KRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSR 136
R+ R+E+ +E +R + +L+R E+ + E+ R+ E R R
Sbjct: 148 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 207
Query: 137 DPSPPRKPRPSRVKAKATAA---TAKTRPSAAATAAARKRALLAANEEEDREIRKLERCL 193
+ S + K A+ + RP R + + E+R++ + +
Sbjct: 208 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 267
Query: 194 GLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLES 253
++RK SS + ESG S + EEEE+ G T ES
Sbjct: 268 SDSERKTSSAESS---------------SAESGSGSEEEEEEEEEEEEEGSTSEES---- 308
Query: 254 DSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR-GKRVRFAE 312
E EEEEE + E+E + EA + +E +EEE E++E+ + RF
Sbjct: 309 ----EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 364
Query: 313 DEEKSENSSED-GDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELERLKKHVKG---- 367
D +SE + E+ G+ T +S + Y+P + + + K+EL + ++G
Sbjct: 365 DSGESEEAEEEVGEGTPQSSALTEGDYVP----DSPALLPIELKQELPKYLPALQGCRSV 420
Query: 368 ----LLNRLSE 374
LNR+ E
Sbjct: 421 EEFQCLNRIEE 431
Score = 34.7 bits (78), Expect = 0.39
Identities = 24/82 (29%), Positives = 37/82 (45%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+EE+ + L SD +D EE E D E + + + ED ED EE
Sbjct: 26 QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAI 85
Query: 297 KGAQEKRRGKRVRFAEDEEKSE 318
K Q+ R ++V +DE++ E
Sbjct: 86 KPPQQMSRKEKVHHRKDEKRKE 107
Score = 33.1 bits (74), Expect = 1.1
Identities = 29/138 (21%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
EE++ A + +++ S E + + E+K + E E E++ E+E
Sbjct: 137 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK---ERE 193
Query: 297 KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKE 356
+ A+E+R+ + R E + + + D +DK + P R+ E D +K
Sbjct: 194 RRAEERRKEREAR---REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 250
Query: 357 ELERLKKHVKGLLNRLSE 374
+ E++++ + LL+ L +
Sbjct: 251 KEEKMEE--RDLLSDLQD 266
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 58.5 bits (140), Expect = 3e-08
Identities = 68/287 (23%), Positives = 117/287 (40%), Gaps = 21/287 (7%)
Query: 68 RGAPVSFRPGG----RKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSG---AEEAS 120
+ AP RP R ++E++ E + Q+ A P L GR+ EEA+
Sbjct: 355 KAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANE---PSLKGRAPLVKVEEAT 411
Query: 121 -GHRQDTEERARPA-PSRDPSPPRKPRPSRVKAKATAATAK--TRPSAAATAAAR-KRAL 175
R E PA P+ P+P P P+ A A T + PS+ A+A K +
Sbjct: 412 VEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSA 471
Query: 176 LAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSS 235
+ EE + +R L +R+K++ R + + + + + + S
Sbjct: 472 GTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEES 531
Query: 236 GEEEEDAGQTLPES---DLESDSQDESEEEEEGDVEKEKKA---QEAEAQSEDDDEDTEE 289
E + + E E + E EE E +KE++A +EAE ++ ++ +
Sbjct: 532 RRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQR 591
Query: 290 EQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGE 336
E+ E E+ + + KR R E +K + +GDI +L G E
Sbjct: 592 EEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTE 638
Score = 33.9 bits (76), Expect = 0.66
Identities = 61/282 (21%), Positives = 101/282 (35%), Gaps = 23/282 (8%)
Query: 129 RARPAPSRDPSPPR-KPRPSRVKAKATAATAKTRPSAAATAAARK-RALLAANEEEDREI 186
+A PA R PSP +P VK + + P A + K RA L EE E
Sbjct: 355 KAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEE 414
Query: 187 RK-LERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQT 245
R E +G +S P + + S ++S + AG T
Sbjct: 415 RTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTT 474
Query: 246 LPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRG 305
PE E + EK+ E + +++ E E+E+ E +++ +R
Sbjct: 475 DPE--------------EATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVA 520
Query: 306 KRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKK-----KEELER 360
+ +EE +E ++ L E+ +AE K+ +EE ER
Sbjct: 521 EERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAER 580
Query: 361 LKKHVKGLLNRLSEPNMASISGQLEELYMAHSRKDMNDTLTS 402
+++ + R E +LEE+ R + D TS
Sbjct: 581 VRQEREKHFQR-EEQERLERKKRLEEIMKRTRRTEATDKKTS 621
Score = 30.4 bits (67), Expect = 7.3
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 11/99 (11%)
Query: 229 SGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGD-------VEKEKKA-QEAEAQS 280
SG ++ + D L D + +++ EE E+ +E+E++A Q E
Sbjct: 44 SGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHL 103
Query: 281 EDDDEDTEEE-QGEEKEKGAQEKRRGKRVRFAEDEEKSE 318
E+ + EE+ Q EE+ + A E++R R R ED+E+ E
Sbjct: 104 EERKKRLEEQRQKEERRRAAVEEKR--RQRLEEDKERHE 140
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 58.2 bits (139), Expect = 3e-08
Identities = 76/322 (23%), Positives = 125/322 (38%), Gaps = 34/322 (10%)
Query: 23 KRRGGRGPRRGPAGGGEKALKRLKLAVEEFV--HATSEGEAPGGCEGRGAPVSFRPGGRK 80
KR+ R R A GG+ A + K E H + +A E + R R+
Sbjct: 70 KRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 129
Query: 81 SRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPSP 140
R L + +R + R+++ ++ E + E AR S
Sbjct: 130 ERDRLEQLERKRERERKMREQQKEQR------EQKERERRAEERRKEREARREVSAHHRT 183
Query: 141 PRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLNKRKK 200
R+ +VKA + + RP R + + E+R++ + + ++RK
Sbjct: 184 MREDYSDKVKASHWSRSPP-RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 242
Query: 201 KDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESE 260
SS + ESG S + EEEE+ G T ES E E
Sbjct: 243 SSAESS---------------SAESGSGSEEEEEEEEEEEEEGSTSEES--------EEE 279
Query: 261 EEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR-GKRVRFAEDEEKSEN 319
EEEE + E+E + EA + +E +EEE E++E+ + RF D +SE
Sbjct: 280 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 339
Query: 320 SSED-GDITDKSLCGSGEKYIP 340
+ E+ G+ T +S + Y+P
Sbjct: 340 AEEEVGEGTPQSSALTEGDYVP 361
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/350 (20%), Positives = 133/350 (38%), Gaps = 22/350 (6%)
Query: 22 MKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGEAPGGCEGRGAPVSFRPGGRKS 81
M + R +R GE R+++ + + + G E ++ +P + S
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDS--LAIKPPQQMS 58
Query: 82 RKE-LRKEKRHLRKARRLQRTAGPEQGPGLGGRSGA----------EEASGHRQDTEERA 130
RKE + K RK +R R+ E G + EE R++ E +
Sbjct: 59 RKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQK 118
Query: 131 RPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLE 190
R +R+ S + R +++ K K R ++R A ++RE R+
Sbjct: 119 RREMAREHSRRERDRLEQLERKRERER-KMREQQKEQREQKERERRAEERRKEREARR-- 175
Query: 191 RCLGLNKRKKKDGSSSVPLS-FARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPES 249
++ ++D S V S ++R E G EE D L +
Sbjct: 176 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 235
Query: 250 DLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDED--TEEEQGEEKEKGAQEKRRGKR 307
SDS+ ++ E E ++E E + E+++E+ T EE EE+E+ +E+
Sbjct: 236 ---SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 292
Query: 308 VRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
E+ +E SE+ D+ + P R ++ + ++ EE
Sbjct: 293 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 342
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 58.2 bits (139), Expect = 3e-08
Identities = 76/322 (23%), Positives = 125/322 (38%), Gaps = 34/322 (10%)
Query: 23 KRRGGRGPRRGPAGGGEKALKRLKLAVEEFV--HATSEGEAPGGCEGRGAPVSFRPGGRK 80
KR+ R R A GG+ A + K E H + +A E + R R+
Sbjct: 104 KRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 163
Query: 81 SRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPSP 140
R L + +R + R+++ ++ E + E AR S
Sbjct: 164 ERDRLEQLERKRERERKMREQQKEQR------EQKERERRAEERRKEREARREVSAHHRT 217
Query: 141 PRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLNKRKK 200
R+ +VKA + + RP R + + E+R++ + + ++RK
Sbjct: 218 MREDYSDKVKASHWSRSPP-RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 276
Query: 201 KDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESE 260
SS + ESG S + EEEE+ G T ES E E
Sbjct: 277 SSAESS---------------SAESGSGSEEEEEEEEEEEEEGSTSEES--------EEE 313
Query: 261 EEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR-GKRVRFAEDEEKSEN 319
EEEE + E+E + EA + +E +EEE E++E+ + RF D +SE
Sbjct: 314 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 373
Query: 320 SSED-GDITDKSLCGSGEKYIP 340
+ E+ G+ T +S + Y+P
Sbjct: 374 AEEEVGEGTPQSSALTEGDYVP 395
Score = 52.0 bits (123), Expect = 2e-06
Identities = 73/356 (20%), Positives = 136/356 (38%), Gaps = 22/356 (6%)
Query: 16 QGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGEAPGGCEGRGAPVSFR 75
+ + R+K R +R GE R+++ + + + G E ++ +
Sbjct: 29 KAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDS--LAIK 86
Query: 76 PGGRKSRKE-LRKEKRHLRKARRLQRTAGPEQGPGLGGRSGA----------EEASGHRQ 124
P + SRKE + K RK +R R+ E G + EE R+
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARR 146
Query: 125 DTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDR 184
+ E + R +R+ S + R +++ K K R ++R A ++R
Sbjct: 147 EWERQKRREMAREHSRRERDRLEQLERKRERER-KMREQQKEQREQKERERRAEERRKER 205
Query: 185 EIRKLERCLGLNKRKKKDGSSSVPLS-FARDGLDYILGALESGKNSGLYDSSGEEEEDAG 243
E R+ ++ ++D S V S ++R E G EE D
Sbjct: 206 EARR--EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL 263
Query: 244 QTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDED--TEEEQGEEKEKGAQE 301
L + SDS+ ++ E E ++E E + E+++E+ T EE EE+E+ +E
Sbjct: 264 SDLQDI---SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 320
Query: 302 KRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
+ E+ +E SE+ D+ + P R ++ + ++ EE
Sbjct: 321 EEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 376
Score = 38.5 bits (88), Expect = 0.027
Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 16/128 (12%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+EE+ + L SD +D EE E D E + + + ED ED EE
Sbjct: 26 QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAI 85
Query: 297 KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKE 356
K Q+ R ++V +DE++ E +S G K H R E K+
Sbjct: 86 KPPQQMSRKEKVHHRKDEKRKEKRRH------RSHSAEGGK----HARVKE------KER 129
Query: 357 ELERLKKH 364
E ER K+H
Sbjct: 130 EHERRKRH 137
Score = 33.1 bits (74), Expect = 1.1
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 257 DESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEK 316
DE +E++ E+E+KA E + DD D++ + EE E + + +
Sbjct: 14 DEILQEKKRRKEQEEKA-EIKRLKNSDDRDSKRDSLEEGEL----RDHRMEITIRNSPYR 68
Query: 317 SENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELERLKKH 364
E+S ED D SL PP +E V +K E+ + ++H
Sbjct: 69 REDSMEDRGEEDDSLA-----IKPPQQMSRKEKVHHRKDEKRKEKRRH 111
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 57.8 bits (138), Expect = 4e-08
Identities = 32/91 (35%), Positives = 52/91 (57%), Gaps = 4/91 (4%)
Query: 236 GEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQS--EDDDEDTEEEQGE 293
G + ED Q P+SD E D DE EE+EEG+ E+++ ++ E + E+DDED + E E
Sbjct: 147 GYDRED--QEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDE 204
Query: 294 EKEKGAQEKRRGKRVRFAEDEEKSENSSEDG 324
+ ++ ++E+ EDE++ E E G
Sbjct: 205 DDDEVSEEEEEFGLDEEDEDEDEDEEEEEGG 235
Score = 54.3 bits (129), Expect = 5e-07
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Query: 233 DSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQG 292
D GE+EED E + E D +D+ +E+ EGD + ++ ++E E D++++ E+E
Sbjct: 171 DEEGEDEEDEDDEDGEEE-EFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDE 229
Query: 293 EEKEKGAQEKRRGKRVRFAEDE 314
EE+E G EKR+ + ED+
Sbjct: 230 EEEEGGKGEKRKRETDDEGEDD 251
Score = 40.0 bits (92), Expect = 0.009
Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 16/70 (22%)
Query: 232 YDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQ 291
+D +E+ED + + D + SEEEEE +++E ED+DED EEE+
Sbjct: 190 FDEEDDEDEDV-------EGDEDDDEVSEEEEEFGLDEE---------DEDEDEDEEEEE 233
Query: 292 GEEKEKGAQE 301
G + EK +E
Sbjct: 234 GGKGEKRKRE 243
Score = 38.5 bits (88), Expect = 0.027
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 7/94 (7%)
Query: 264 EGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSED 323
+G ++++A +++A+ + DE+ E+E+GE++E ++ G+ F DEE E+ +
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEED--EDDEDGEEEEF--DEEDDEDEDVE 201
Query: 324 GDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
GD D + E++ + + +E D ++EE
Sbjct: 202 GDEDDDEVSEEEEEF---GLDEEDEDEDEDEEEE 232
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 57.8 bits (138), Expect = 4e-08
Identities = 64/269 (23%), Positives = 109/269 (40%), Gaps = 30/269 (11%)
Query: 79 RKSRKELRKE--KRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSR 136
R+ R+E+ +E +R + +L+R E+ + E+ R+ E R R
Sbjct: 139 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 198
Query: 137 DPSPPRKPRPSRVKAKATAA---TAKTRPSAAATAAARKRALLAANEEEDREIRKLERCL 193
+ S + K A+ + RP R + + E+R++ + +
Sbjct: 199 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 258
Query: 194 GLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLES 253
++RK SS + ESG S + EEEE+ G T ES
Sbjct: 259 SDSERKTSSAESS---------------SAESGSGSEEEEEEEEEEEEEGSTSEES---- 299
Query: 254 DSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR-GKRVRFAE 312
E EEEEE + E+E + EA + +E +EEE E++E+ + RF
Sbjct: 300 ----EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 355
Query: 313 DEEKSENSSED-GDITDKSLCGSGEKYIP 340
D +SE + E+ G+ T +S + Y+P
Sbjct: 356 DSGESEEAEEEVGEGTPQSSALTEGDYVP 384
Score = 50.1 bits (118), Expect = 9e-06
Identities = 74/356 (20%), Positives = 136/356 (38%), Gaps = 33/356 (9%)
Query: 16 QGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGEAPGGCEGRGAPVSFR 75
+ + R+K R +R GE +++ + + + G E ++ +
Sbjct: 29 KAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS--LAIK 86
Query: 76 PGGRKSRKEL--------RKEKRHLR---KARRLQRTAGPEQGPGLGGRSGAEEASGHRQ 124
P + SRKE RKEK+H R K R +R + EE R+
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR-----------KRHREEQDKARR 135
Query: 125 DTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDR 184
+ E + R +R+ S + R +++ K K R ++R A ++R
Sbjct: 136 EWERQKRREMAREHSRRERDRLEQLERKRERER-KMREQQKEQREQKERERRAEERRKER 194
Query: 185 EIRKLERCLGLNKRKKKDGSSSVPLS-FARDGLDYILGALESGKNSGLYDSSGEEEEDAG 243
E R+ ++ ++D S V S ++R E G EE D
Sbjct: 195 EARR--EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL 252
Query: 244 QTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDED--TEEEQGEEKEKGAQE 301
L + SDS+ ++ E E ++E E + E+++E+ T EE EE+E+ +E
Sbjct: 253 SDLQDI---SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 309
Query: 302 KRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
+ E+ +E SE+ D+ + P R ++ + ++ EE
Sbjct: 310 EEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 365
Score = 34.7 bits (78), Expect = 0.39
Identities = 24/82 (29%), Positives = 37/82 (45%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+EE+ + L SD +D EE E D E + + + ED ED EE
Sbjct: 26 QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAI 85
Query: 297 KGAQEKRRGKRVRFAEDEEKSE 318
K Q+ R ++V +DE++ E
Sbjct: 86 KPPQQMSRKEKVHHRKDEKRKE 107
Score = 31.6 bits (70), Expect = 3.3
Identities = 28/129 (21%), Positives = 55/129 (42%), Gaps = 19/129 (14%)
Query: 238 EEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEK 297
+E+D+ + ++ + + E+EE+ ++++ K + DD D++ + EE E
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNS---------DDRDSKRDSLEEGEL 53
Query: 298 GAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
+ + + E+S ED D SL PP +E V +K+E
Sbjct: 54 ----RDHCMEITIRNSPYRREDSMEDRGEEDDSLA-----IKPPQQMSRKEKV-HHRKDE 103
Query: 358 LERLKKHVK 366
+ KKH +
Sbjct: 104 KRKEKKHAR 112
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 57.8 bits (138), Expect = 4e-08
Identities = 64/269 (23%), Positives = 109/269 (40%), Gaps = 30/269 (11%)
Query: 79 RKSRKELRKE--KRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSR 136
R+ R+E+ +E +R + +L+R E+ + E+ R+ E R R
Sbjct: 105 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 164
Query: 137 DPSPPRKPRPSRVKAKATAA---TAKTRPSAAATAAARKRALLAANEEEDREIRKLERCL 193
+ S + K A+ + RP R + + E+R++ + +
Sbjct: 165 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 224
Query: 194 GLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLES 253
++RK SS + ESG S + EEEE+ G T ES
Sbjct: 225 SDSERKTSSAESS---------------SAESGSGSEEEEEEEEEEEEEGSTSEES---- 265
Query: 254 DSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR-GKRVRFAE 312
E EEEEE + E+E + EA + +E +EEE E++E+ + RF
Sbjct: 266 ----EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 321
Query: 313 DEEKSENSSED-GDITDKSLCGSGEKYIP 340
D +SE + E+ G+ T +S + Y+P
Sbjct: 322 DSGESEEAEEEVGEGTPQSSALTEGDYVP 350
Score = 50.1 bits (118), Expect = 9e-06
Identities = 74/350 (21%), Positives = 134/350 (38%), Gaps = 33/350 (9%)
Query: 22 MKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGEAPGGCEGRGAPVSFRPGGRKS 81
M + R +R GE R+++ + + + G E ++ +P + S
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDS--LAIKPPQQMS 58
Query: 82 RKEL--------RKEKRHLR---KARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERA 130
RKE RKEK+H R K R +R + EE R++ E +
Sbjct: 59 RKEKVHHRKDEKRKEKKHARVKEKEREHERR-----------KRHREEQDKARREWERQK 107
Query: 131 RPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLE 190
R +R+ S + R +++ K K R ++R A ++RE R+
Sbjct: 108 RREMAREHSRRERDRLEQLERKRERER-KMREQQKEQREQKERERRAEERRKEREARR-- 164
Query: 191 RCLGLNKRKKKDGSSSVPLS-FARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPES 249
++ ++D S V S ++R E G EE D L +
Sbjct: 165 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 224
Query: 250 DLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDED--TEEEQGEEKEKGAQEKRRGKR 307
SDS+ ++ E E ++E E + E+++E+ T EE EE+E+ +E+
Sbjct: 225 ---SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 281
Query: 308 VRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
E+ +E SE+ D+ + P R ++ + ++ EE
Sbjct: 282 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 331
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 57.4 bits (137), Expect = 6e-08
Identities = 98/360 (27%), Positives = 138/360 (38%), Gaps = 72/360 (20%)
Query: 8 GEAGPGGSQGRVVRMKRRG--------GRGPRRGPAGGGEKALKRLKLAVEEFVH--ATS 57
G GPG SQG V G + P+ G A G A +R E H TS
Sbjct: 1728 GGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQER-----EGKTHNSETS 1782
Query: 58 EGEAPGGCEGRGAPVSFR--PGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLG-GRS 114
G G E G +S R GG+ S E + + AG +Q PG G
Sbjct: 1783 AGSELGEAEQEGEGISERGETGGQGSGHEDNLQG---------EAAAGGDQDPGQSDGAE 1833
Query: 115 GAE--EASGHRQDTEE--RARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAA 170
G E EA G Q E A A + +P +A A + +P
Sbjct: 1834 GIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP-------- 1885
Query: 171 RKRALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESG---- 226
E ED E + E + + +G+ + + ALE+
Sbjct: 1886 ---------ESEDVETPEAE----WEVQPESEGAEAPEAEKEAQPETESVEALETEGEDE 1932
Query: 227 -KNSGLYDSSGEE--EEDAGQTLPESDL------ESDSQDESEEEEEGDVEKEKKAQEAE 277
++ G EE +E GQT PES++ E ++Q ESE+ E +VE E + E E
Sbjct: 1933 PESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE 1992
Query: 278 AQSEDDDEDTEEEQGE--EKEKGAQEKRRGKRVR-FAEDEEKSENSSE----DGDITDKS 330
AQ E +D + E +GE E E+ AQ + G + +E EE E E +GD +S
Sbjct: 1993 AQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPES 2052
Score = 44.7 bits (104), Expect = 4e-04
Identities = 50/218 (22%), Positives = 85/218 (38%), Gaps = 26/218 (11%)
Query: 116 AEEASGHRQDTEERARPAPSRDPSPPRKP--RPSRVKAKATAATAKTRPSAAATAAARKR 173
A EA G Q+ EE A+P + P+ V+ + +P + A
Sbjct: 2002 APEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPE-- 2059
Query: 174 ALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFAR---DGLDYILGALESGKNSG 230
A EE +++ G + +D + A+ +G++ E+ K G
Sbjct: 2060 ----AEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115
Query: 231 LYDSSGEEEEDAGQTLPESD------LESDSQDESE----EEEEGDVEKEKKAQEAEAQS 280
+ E E G+ PES+ E ++Q ESE ++ EG+ + E + EA+
Sbjct: 2116 I-----EAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170
Query: 281 EDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSE 318
E+ + E + E E AQ + G AE E + E
Sbjct: 2171 EEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPE 2208
Score = 39.7 bits (91), Expect = 0.012
Identities = 51/253 (20%), Positives = 90/253 (35%), Gaps = 34/253 (13%)
Query: 84 ELRKEKRHLRKARRLQRTAGPEQGPGLGGRS-----GAEEASGHRQDTEERARPAPSRDP 138
E KE + ++ T G ++ G + A+EA G Q E + +
Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEE 1969
Query: 139 SPPRKP--RPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLN 196
+ P V+ + A + +P + A + EEE
Sbjct: 1970 AQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEE-------------- 2015
Query: 197 KRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQ 256
+ + DG + P S + + + G + + +S G E +A + E++ E
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQE-VEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEA 2074
Query: 257 DESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGE----------EKEKGAQEKRRGK 306
+ E DV+ ++ E EAQ E + + E +GE E E AQ + G
Sbjct: 2075 EGEAHPESEDVDAQE--AEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGI 2132
Query: 307 RVRFAEDEEKSEN 319
AE E + E+
Sbjct: 2133 EAPEAEGEAQPES 2145
Score = 39.7 bits (91), Expect = 0.012
Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 16/97 (16%)
Query: 234 SSGEEEEDA-GQTLPESDLESDSQDESE-------EEEEGDVEKEKKAQEAEAQSEDDDE 285
S GEE ++ G+T E D+Q ES+ EEE + E E + E EA E +D
Sbjct: 2029 SEGEEAQEVEGET---QKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV 2085
Query: 286 DTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSE 322
D +E +GE AQ + G AE E + E
Sbjct: 2086 DAQEAEGE-----AQPESEGVEAPEAEGEAQKAEGIE 2117
Score = 37.4 bits (85), Expect = 0.060
Identities = 70/288 (24%), Positives = 106/288 (36%), Gaps = 54/288 (18%)
Query: 103 GPEQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRP 162
G E P G A+E G Q TE A+P +P + + + A + P
Sbjct: 2022 GVEAQPKSEGEE-AQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHP 2080
Query: 163 SAAATAAARKRALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGA 222
+ A A E E +E + +K +G + + A
Sbjct: 2081 ESEDVDAQE------AEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEA 2134
Query: 223 LESGKNSGLYDSSGEEEEDA-GQTLPESD--------------LES----DSQDESEEEE 263
E+ + +S G E +DA G+ PES+ LE +++ E++ E
Sbjct: 2135 PEA-EGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPES 2193
Query: 264 EG--DVEKEKKAQ-----------EAEAQSEDDDEDTEEEQGE---EKEKGAQEKRRGK- 306
EG E E +AQ E EAQ E + +T E +GE E E Q +++G
Sbjct: 2194 EGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSP 2253
Query: 307 --RVRFAEDEEKSENSS---EDGDITDKSLCGSGEKYIPPHVRQAEET 349
+ + EE SE+SS ED S G PH R +T
Sbjct: 2254 QVSLGDGQSEEASESSSPVPEDRPTPPPSPGGD-----TPHQRPGSQT 2296
Score = 36.6 bits (83), Expect = 0.10
Identities = 56/233 (24%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Query: 203 GSSSVPLSF----ARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPES-DLESDSQD 257
G SSVP + G + L +S Y+S G+ E P + + +
Sbjct: 1211 GESSVPCAMDGTLVTQGTELPLKTSNQRPDSRTYESPGDLENQQQCCFPTFLNARACACA 1270
Query: 258 ESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKS 317
+E+E E D E+++ + E +E+ + EE Q EE ++G + + + E+ +
Sbjct: 1271 TNEDEAERDSEEQRASSNLEQLAENTVQ--EEVQLEETKEGTEGEGLQEEAVQLEETKTE 1328
Query: 318 ENSSEDGDITD--KSLCGSGEKYIPPHVRQAEETVDFKKKEE---LERLKKHVKGLL--N 370
E E+G + K G G++ + + EET +EE LE +K+ +G L
Sbjct: 1329 EGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGE 1388
Query: 371 RLSE-------PNMASISGQ-LEELYMAHSRKDMNDTLTSALMGACVTASAMP 415
L E P S+ GQ L E + D +ASA P
Sbjct: 1389 ALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEP 1441
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 57.4 bits (137), Expect = 6e-08
Identities = 67/288 (23%), Positives = 113/288 (39%), Gaps = 31/288 (10%)
Query: 83 KELRKEKRHLRKARRLQRTA-GPEQGPG---LGGRSGAEEASGHRQDTEERARPAPSRDP 138
KEL + + +R+A+ A PE G GGRS + S R ++ +R S+
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332
Query: 139 SPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLNKR 198
R SR + K + + + RK + + ++ ++ R E+ +
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR--EKIKEKERV 390
Query: 199 KKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDE 258
K+KD R+ E GKN D E E+D E D E D + E
Sbjct: 391 KEKDREKEREREKEREK------EKERGKNK---DRDKEREKDR-----EKDKEKDRERE 436
Query: 259 SEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQ------EKRRGKRVRFAE 312
E+E E D +KEK+ ++ + + + D E ++ +K+K ++ R R E
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496
Query: 313 DEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELER 360
+ SS T K++ + P R ++ KK E ER
Sbjct: 497 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-----KKREKER 539
Score = 30.8 bits (68), Expect = 5.6
Identities = 58/344 (16%), Positives = 117/344 (34%), Gaps = 49/344 (14%)
Query: 39 EKALKRLKLAVEEFVHATSEGEAPGGCEGRG----------APVSFRPGGRKSRKELRKE 88
E+ +KR++ A + F+ A E E+ E +G + S + R+ R + +
Sbjct: 276 EEVMKRVREA-QSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHR 334
Query: 89 KRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGH--------RQDTEERARP---APSRD 137
R ++R Q+ + P E R+DT E+ + +D
Sbjct: 335 SRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD 394
Query: 138 PSPPRKPRPSRVKAKATAATA---------------KTRPSAAATAAARKRALLAANEEE 182
R+ R K K K R + R E++
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454
Query: 183 DREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDA 242
+ R+ +R +++++KKD S P R S + S
Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTP---PRSYNASRRSRSSSRERRRRRSRSSSRSPRT 511
Query: 243 GQTLPESDLESDS------QDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+T+ S S +D+ E+E + + ++ + + + + ++ +E+ E+
Sbjct: 512 SKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNS 571
Query: 297 KGAQEKRRGKRVRFA---EDEEKSENSSEDGDITDKSLCGSGEK 337
+EK K + E ++K +E+ I C E+
Sbjct: 572 TSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEE 615
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 57.4 bits (137), Expect = 6e-08
Identities = 67/288 (23%), Positives = 113/288 (39%), Gaps = 31/288 (10%)
Query: 83 KELRKEKRHLRKARRLQRTA-GPEQGPG---LGGRSGAEEASGHRQDTEERARPAPSRDP 138
KEL + + +R+A+ A PE G GGRS + S R ++ +R S+
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216
Query: 139 SPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLNKR 198
R SR + K + + + RK + + ++ ++ R E+ +
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR--EKIKEKERV 274
Query: 199 KKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDE 258
K+KD R+ E GKN D E E+D E D E D + E
Sbjct: 275 KEKDREKEREREKEREK------EKERGKNK---DRDKEREKDR-----EKDKEKDRERE 320
Query: 259 SEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQ------EKRRGKRVRFAE 312
E+E E D +KEK+ ++ + + + D E ++ +K+K ++ R R E
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380
Query: 313 DEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELER 360
+ SS T K++ + P R ++ KK E ER
Sbjct: 381 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-----KKREKER 423
Score = 30.8 bits (68), Expect = 5.6
Identities = 58/344 (16%), Positives = 117/344 (34%), Gaps = 49/344 (14%)
Query: 39 EKALKRLKLAVEEFVHATSEGEAPGGCEGRG----------APVSFRPGGRKSRKELRKE 88
E+ +KR++ A + F+ A E E+ E +G + S + R+ R + +
Sbjct: 160 EEVMKRVREA-QSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHR 218
Query: 89 KRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGH--------RQDTEERARP---APSRD 137
R ++R Q+ + P E R+DT E+ + +D
Sbjct: 219 SRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD 278
Query: 138 PSPPRKPRPSRVKAKATAATA---------------KTRPSAAATAAARKRALLAANEEE 182
R+ R K K K R + R E++
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338
Query: 183 DREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDA 242
+ R+ +R +++++KKD S P R S + S
Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTP---PRSYNASRRSRSSSRERRRRRSRSSSRSPRT 395
Query: 243 GQTLPESDLESDS------QDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+T+ S S +D+ E+E + + ++ + + + + ++ +E+ E+
Sbjct: 396 SKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNS 455
Query: 297 KGAQEKRRGKRVRFA---EDEEKSENSSEDGDITDKSLCGSGEK 337
+EK K + E ++K +E+ I C E+
Sbjct: 456 TSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEE 499
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 57.0 bits (136), Expect = 7e-08
Identities = 66/268 (24%), Positives = 106/268 (39%), Gaps = 60/268 (22%)
Query: 79 RKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGH----RQDTEERARPAP 134
R+ +KE R++K R+A ++ R E S H R+D ++ + A
Sbjct: 180 REQQKEQREQKERERRAEERRKE-----------REARREVSAHHRTMREDYSDKVK-AS 227
Query: 135 SRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLG 194
SPPR PR R + + E+R++ + +
Sbjct: 228 HWSRSPPRPPRERFELGDG-------------------RKPVKEEKMEERDLLSDLQDIS 268
Query: 195 LNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESD 254
++RK SS + ESG S + EEEE+ G T ES
Sbjct: 269 DSERKTSSAESS---------------SAESGSGSEEEEEEEEEEEEEGSTSEES----- 308
Query: 255 SQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRR-GKRVRFAED 313
E EEEEE + E+E + EA + +E +EEE E++E+ + RF D
Sbjct: 309 ---EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD 365
Query: 314 EEKSENSSED-GDITDKSLCGSGEKYIP 340
+SE + E+ G+ T +S + Y+P
Sbjct: 366 SGESEEAEEEVGEGTPQSSALTEGDYVP 393
Score = 45.4 bits (106), Expect = 2e-04
Identities = 77/373 (20%), Positives = 144/373 (38%), Gaps = 48/373 (12%)
Query: 16 QGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGEAPGGCEGRGAPVSFR 75
+ + R+K R +R GE +++ + + + G E ++ +
Sbjct: 29 KAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS--LAIK 86
Query: 76 PGGRKSRKEL--------RKEKRHLR---KARRLQRTAGPEQGPGLGGRSGAEEASGHRQ 124
P + SRKE RKEK+H R K R +R + EE R+
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR-----------KRHREEQDKARR 135
Query: 125 DTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDR 184
+ E + R +R+ S R + + R R+R + ++E R
Sbjct: 136 EWERQKRREMAREHS-------RRERGNDGVCLFRDRLEQLERKRERERKM-REQQKEQR 187
Query: 185 EIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAG- 243
E ++ ER +RK+++ V DY +++ S E + G
Sbjct: 188 EQKERER-RAEERRKEREARREVSAHHRTMREDYS-DKVKASHWSRSPPRPPRERFELGD 245
Query: 244 -------QTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEA--QSEDDDEDTEEE--QG 292
+ + E DL SD QD S+ E + + A+ + E+++E+ EEE
Sbjct: 246 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 305
Query: 293 EEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDF 352
EE E+ +E+ + + EE SE S+E +++++ + E+ H+ E+
Sbjct: 306 EESEEEEEEEEEEEEETGSNSEEASEQSAE--EVSEEEMSEDEERENENHLLVVPESRFD 363
Query: 353 KKKEELERLKKHV 365
+ E E ++ V
Sbjct: 364 RDSGESEEAEEEV 376
Score = 34.7 bits (78), Expect = 0.39
Identities = 24/82 (29%), Positives = 37/82 (45%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+EE+ + L SD +D EE E D E + + + ED ED EE
Sbjct: 26 QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAI 85
Query: 297 KGAQEKRRGKRVRFAEDEEKSE 318
K Q+ R ++V +DE++ E
Sbjct: 86 KPPQQMSRKEKVHHRKDEKRKE 107
Score = 31.6 bits (70), Expect = 3.3
Identities = 28/129 (21%), Positives = 55/129 (42%), Gaps = 19/129 (14%)
Query: 238 EEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEK 297
+E+D+ + ++ + + E+EE+ ++++ K + DD D++ + EE E
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNS---------DDRDSKRDSLEEGEL 53
Query: 298 GAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
+ + + E+S ED D SL PP +E V +K+E
Sbjct: 54 ----RDHCMEITIRNSPYRREDSMEDRGEEDDSLA-----IKPPQQMSRKEKV-HHRKDE 103
Query: 358 LERLKKHVK 366
+ KKH +
Sbjct: 104 KRKEKKHAR 112
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 57.0 bits (136), Expect = 7e-08
Identities = 64/265 (24%), Positives = 111/265 (41%), Gaps = 23/265 (8%)
Query: 117 EEASGHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALL 176
EE R++ EER K R R+K + T R + A A K
Sbjct: 370 EELEAKRKE-EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQA 428
Query: 177 AANEEEDREIRKLERCLGLNKRKKK--------DGSSSVPLSFARDGLDYILGALESGKN 228
E ++ +R + +K++KK + S S+ L A + ++ G E +
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ--GVPEKEET 486
Query: 229 SGLYDSSGEEE-EDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDT 287
+ EE+ EDAG D E+ + DE E+ EG+ + + E + E+++E+
Sbjct: 487 PPPVEPEEEEDTEDAGL----DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542
Query: 288 EEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDK---SLCGSGEKYIPPHVR 344
E+E+ EE+E +E+ + E++EK + + G DK S +Y R
Sbjct: 543 EDEESEEEE---EEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDR 599
Query: 345 QAEETVDFKKKEELERLK-KHVKGL 368
EE K K +E+ + +H K +
Sbjct: 600 TKEERAYDKAKRRIEKRRLEHSKNV 624
Score = 45.4 bits (106), Expect = 2e-04
Identities = 65/333 (19%), Positives = 136/333 (40%), Gaps = 22/333 (6%)
Query: 66 EGRGAPVSFRPGGRKSRKELRKEKRHLRK---ARRLQRTAGPEQGPGLGGRSGAEEASGH 122
EG GA P K +K+ K+K+ + + L+ + QG A+ +
Sbjct: 27 EGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQG------IKADRETVA 80
Query: 123 RQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEE 182
+ TE S+D + + + + + S + A K + + ++++
Sbjct: 81 VKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDD 140
Query: 183 D--REIRKLERCLGLNKRKKKDGSSSVPLSFAR-DGLDYILGALESGKNSGLYDSSGEEE 239
D ++ K + KK DGS + + I + ESG S + S + +
Sbjct: 141 DDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQ 200
Query: 240 EDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE--- 296
+ + P ++ES ++D+ + V ++K ++ + + D+E + + +EKE
Sbjct: 201 KKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELE 260
Query: 297 --KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKK 354
K Q K++ + +F E+ KS+ + + G I S EK P + + D KK
Sbjct: 261 TGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP-----ASEEKAETPTAAEDDNEGDKKK 315
Query: 355 KEELERLKKHVKGLLNRLSEPNMASISGQLEEL 387
K++ ++ + + + P+ A++ E L
Sbjct: 316 KDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL 348
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/260 (21%), Positives = 97/260 (37%), Gaps = 36/260 (13%)
Query: 113 RSGAEEASGHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARK 172
RS + +++E + + + KP P+ + + A A +K
Sbjct: 177 RSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKK 236
Query: 173 RALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLY 232
+EE ++RKL+ L KK + E+ K+
Sbjct: 237 ERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEE---------ETVKSKVTV 287
Query: 233 DSS---GEEEEDAGQTLPESDLESDSQDESEEEEEGDVE---KEKKAQEAEAQSEDDDED 286
D+ EE+ T E D E D + + +++++G+ E KEKK ++A + E
Sbjct: 288 DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA 347
Query: 287 TEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQA 346
+ + EE+ + +E+ R KR+ E + K E E ++
Sbjct: 348 LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE---------------------QEK 386
Query: 347 EETVDFKKKEELERLKKHVK 366
E K+KE ERLKK K
Sbjct: 387 RERKKQKEKERKERLKKEGK 406
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 56.6 bits (135), Expect = 1e-07
Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 8/118 (6%)
Query: 224 ESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDD 283
ESG S + EEEE+ G T ES+ E + ++E EEEE G +E Q AE SE++
Sbjct: 29 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE-EEEETGSNSEEASEQSAEEVSEEE 87
Query: 284 DEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSED-GDITDKSLCGSGEKYIP 340
+ EE + E E RF D +SE + E+ G+ T +S + Y+P
Sbjct: 88 MSEDEERENENHLLVVPES------RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 139
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 229 SGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTE 288
S L D S E + + + S ES S E EEEEE + E+E E + E+++E+ E
Sbjct: 8 SDLQDISDSERKTS--SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 65
Query: 289 EEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSS 321
EE G E+ +++ ++E+ EN +
Sbjct: 66 EETGSNSEEASEQSAEEVSEEEMSEDEERENEN 98
Score = 43.5 bits (101), Expect = 8e-04
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 16/129 (12%)
Query: 246 LPESDLESDSQDESEEE------EEGDVEKEKKAQEAEAQSEDDDED---TEEEQGEEKE 296
+ E DL SD QD S+ E E E ++E E + E+++E+ +EE + EE+E
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60
Query: 297 KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKE 356
+ +E+ G + EE SE S+E +++++ + E+ H+ E+ +
Sbjct: 61 EEEEEEETG-----SNSEEASEQSAE--EVSEEEMSEDEERENENHLLVVPESRFDRDSG 113
Query: 357 ELERLKKHV 365
E E ++ V
Sbjct: 114 ESEEAEEEV 122
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 56.6 bits (135), Expect = 1e-07
Identities = 64/295 (21%), Positives = 121/295 (41%), Gaps = 31/295 (10%)
Query: 68 RGAPVSFRPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTE 127
RG S P GR RKE KE AGPE +S ++ + + +++
Sbjct: 498 RGTTAS--PKGRVRRKEEAKES---------PSAAGPED------KSQSKRRASNEKESA 540
Query: 128 ERARPAPSRDPSP-PRKPRPSRVKAKA-TAATAKTRPSAAATAAARKRALLAANEEEDRE 185
A PAPS PSP P P+ + A+ T A T P A A + + + E+
Sbjct: 541 APASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEAT 600
Query: 186 IRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQT 245
E+ ++++++ L RD + + L + E +
Sbjct: 601 RLLAEKRRQAREQRERE-EQERRLQAERD---------KRMREEQLAREAEARAEREAEA 650
Query: 246 LPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRG 305
+ E+ + ++E+EE+ ++K+K+ EA ++ E + + E E+ ++++ +++RR
Sbjct: 651 RRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRK 710
Query: 306 KRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELER 360
+ + KSE S K +G P V+ E +KE +++
Sbjct: 711 RLEEIMKRTRKSEVSETKQKQDSKEANANGSS--PEPVKAVEARSPGLQKEAVQK 763
Score = 49.7 bits (117), Expect = 1e-05
Identities = 89/408 (21%), Positives = 142/408 (34%), Gaps = 48/408 (11%)
Query: 4 SRSAGEAGPGGSQGRVVRMKRRGGRGPRRGPAGGGEKALKRLKLAVEEFVHATSEGEAPG 63
S SA P V R G RG RR P GG A R + + +
Sbjct: 364 SASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERE 423
Query: 64 GCEGRGAPVSFRPGGRKSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHR 123
+ + A R K R+ L R RL + E P R + S HR
Sbjct: 424 NEKEKSALA--RERSLKKRQSLPASPR-----ARLSASTASELSPKSKARPSSPSTSWHR 476
Query: 124 QDTEERARPAPSRDPS---PPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANE 180
A P PS P PP+ P P + T A+ K R A K + AA
Sbjct: 477 P-----ASPCPSPGPGHTLPPKPPSP-----RGTTASPKGRVRRKEEA---KESPSAAGP 523
Query: 181 EEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGA--------LESGKNSGLY 232
E+ + ++ R + S+ P S A A E+ ++ +
Sbjct: 524 EDKSQSKR---------RASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVL 574
Query: 233 DSSGEEEEDAGQTLP---ESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEE 289
S + P +D E ++ +E+ + ++E++ QE Q+E D EE
Sbjct: 575 TSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREE 634
Query: 290 EQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEET 349
+ E E A+ + +R E EK++ E+ + K + + RQ E
Sbjct: 635 QLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLER 694
Query: 350 VDFKKKEELERLKKHVKGLLNRLSEPNMASISGQLEELYMAHSRKDMN 397
+++E ER ++ RL E + ++ E K+ N
Sbjct: 695 EKHFQQQEQERQERR-----KRLEEIMKRTRKSEVSETKQKQDSKEAN 737
Score = 33.5 bits (75), Expect = 0.87
Identities = 59/265 (22%), Positives = 97/265 (36%), Gaps = 30/265 (11%)
Query: 105 EQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPSPPRKPR--------PSRVKAKATAA 156
E GP +GA A R T RP+P DPSPP P P A A
Sbjct: 2 ESGPRAELGAGAPPAVVAR--TPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNAT 59
Query: 157 TAKTRPSAAATAAARKRALLAANEEEDREIRKLER-----CLGLNKRKKKDGSSSVPLSF 211
++K P + + + A +EE R +G + + SS P
Sbjct: 60 SSKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMG-PRDARPPRRSSQPSPT 118
Query: 212 ARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESD---LESDSQDESEEEEEGDVE 268
A D E K + + E E+ + L LE + + ++ E++ E
Sbjct: 119 AVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQ-E 177
Query: 269 KEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEK----RRGKRVRFAEDEEK------SE 318
+ ++ +E ++E EE Q ++ EK + +R + +AE ++ +
Sbjct: 178 RRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGAL 237
Query: 319 NSSEDGDITDKSLCGSGEKYIPPHV 343
+ S G T S C +P HV
Sbjct: 238 HHSSPGHKTSGSRCSVSAVNLPKHV 262
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 56.2 bits (134), Expect = 1e-07
Identities = 59/233 (25%), Positives = 100/233 (42%), Gaps = 34/233 (14%)
Query: 124 QDTEERARPAPSRDPSPPRK---PRPSRVKAKATAA-------TAKTRPSAAATAAARKR 173
+D+E+ D S + P+ KA AT+A T K + A AA
Sbjct: 26 EDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTP 85
Query: 174 ALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYD 233
AA + + + K+ G + V + GA ++GKN+ D
Sbjct: 86 GKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGA-KNGKNAKKED 144
Query: 234 SSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEA------QSEDDDEDT 287
S EE++D+ E D E D +DE E+E+E + K A A A + ++DDED
Sbjct: 145 SDEEEDDDS-----EED-EEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDD 198
Query: 288 EEEQGEEKEKGAQE--KRRGKRV---------RFAEDEEKSENSSEDGDITDK 329
++++ ++ E+ A E +GK+ AEDE++ E+ ++ D D+
Sbjct: 199 DDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE 251
Score = 45.8 bits (107), Expect = 2e-04
Identities = 25/102 (24%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Query: 233 DSSGEEEEDAGQTLPESDLES------DSQDESEEEEEGDVEKEKKAQEAEAQSEDDDED 286
D + EE+A +T P ++ +++ +E+E+E + ++++ + E +DDDED
Sbjct: 201 DEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDED 260
Query: 287 TEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITD 328
EEE+ EE+E+ +E ++ A+ + E + + T+
Sbjct: 261 DEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/208 (24%), Positives = 83/208 (39%), Gaps = 16/208 (7%)
Query: 130 ARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKL 189
A PA +P +K + K T A A T P A +AL+A ++ I
Sbjct: 75 ATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKG--ATPGKALVATPGKKGAAIPAK 132
Query: 190 ERCLGLNKRKK-----KDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQ 244
G N +K+ +D S D D +E + E+ED
Sbjct: 133 GAKNGKNAKKEDSDEEEDDDSEEDEEDDEDE-DEDEDEIEPAAMKAAAAAPASEDEDDED 191
Query: 245 TLPESDLESDSQDESEEEE-EGDVEKEKKAQEA---EAQSEDDDEDTEEEQGEEKEKGAQ 300
+ D + D +D+SEEE E K KKA + +A++ +DED EE+ +E + +
Sbjct: 192 DEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE 251
Query: 301 EKRRGKRVRFAEDEEKSENSSEDGDITD 328
+ ED+E+ E E+ + +
Sbjct: 252 DDEDDD----DEDDEEEEEEEEEEPVKE 275
Score = 38.5 bits (88), Expect = 0.027
Identities = 41/198 (20%), Positives = 68/198 (34%), Gaps = 37/198 (18%)
Query: 104 PEQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPS 163
P +G G + E++ D E + + P+ +KA A A ++
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDD 189
Query: 164 AAATAAARKRALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGAL 223
++++D E E + K K + VP+
Sbjct: 190 EDDEDDE--------DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVK------------- 228
Query: 224 ESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVE--------------K 269
KN + E++ED E D + D +D+ EEEEE + E K
Sbjct: 229 --AKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAK 286
Query: 270 EKKAQEAEAQSEDDDEDT 287
+K A EA+ Q + E T
Sbjct: 287 QKAAPEAKKQKVEGTEPT 304
Score = 37.0 bits (84), Expect = 0.078
Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 11/104 (10%)
Query: 256 QDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEE 315
+++S+EEE+ D E++ ++D++ E+E +E E A + ED+E
Sbjct: 142 KEDSDEEEDDDSEED-----------EEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDE 190
Query: 316 KSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELE 359
E+ +D D + + P ++A + V K K E
Sbjct: 191 DDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 56.2 bits (134), Expect = 1e-07
Identities = 42/154 (27%), Positives = 74/154 (48%), Gaps = 21/154 (13%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
+E+E+ E E + +D+ +E+EE E+E+K QE E + + +E E+ EEK
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ--EEKM 662
Query: 297 KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEK---------------YIPP 341
+ +EK +G+ + E EEK + E ++ + G EK +
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 722
Query: 342 HVRQAEETVDFKKKEELERLKKHVKGLLNRLSEP 375
+R+ EE + +K++ ERL +H + R SEP
Sbjct: 723 EMREKEERIRDQKEKMQERLPEHEE----RCSEP 752
Score = 44.7 bits (104), Expect = 4e-04
Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 11/127 (8%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
EE+E Q LPE + Q++ +E+EE E+E+K + D EE G+EK+
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR-----------DQEEMWGQEKK 474
Query: 297 KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKE 356
QEK R + + E EEK + + ++ + E+ R E+ ++++E
Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
Query: 357 ELERLKK 363
++ KK
Sbjct: 535 KMREEKK 541
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 14/134 (10%)
Query: 237 EEEE---DAGQTLPESDLESDSQDES--EEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQ 291
EEEE + + + E + + Q+E E+EE+ ++EK ++ E E ++ED +EQ
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 292 GEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETV- 350
EE +EK + + + E EEK E ++ + G EK +R+ EE +
Sbjct: 631 -EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK-----MREQEEKMQ 684
Query: 351 --DFKKKEELERLK 362
+ K +E+ E+++
Sbjct: 685 GQEEKMREQEEKMR 698
Score = 40.8 bits (94), Expect = 0.005
Identities = 36/159 (22%), Positives = 73/159 (45%), Gaps = 9/159 (5%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEE-----Q 291
EE+ + E + ++ Q+E EEE E+EKK +E E + +E +E+ +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 292 GEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKS--LCGSGEKYIPPHVRQAEET 349
EEK +EK + + + E EEK E+ + ++ + EK + E+
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
Query: 350 VDFKKKEE-LERLKKHVKGLLNRLSEPNMASISGQLEEL 387
+++EE + ++ ++G ++ E + GQ E++
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMREQE-EKMQGQEEKM 690
Score = 38.5 bits (88), Expect = 0.027
Identities = 26/107 (24%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 254 DSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAED 313
D ++ E++E EKE++ +E E E +++ EEE+ E+EK +E+ R + +
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 314 EEKSEN--SSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEEL 358
+++ EN E+ + + L EK Q +E ++++E++
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
Score = 38.1 bits (87), Expect = 0.035
Identities = 34/144 (23%), Positives = 68/144 (47%), Gaps = 13/144 (9%)
Query: 233 DSSGEEEE---DAGQTLPESDLESDSQDESEEEEEGDVEKEKKA--QEAEAQSEDDDEDT 287
D E+EE D Q + + + QDE E+E + ++KK QE + + E ++
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 288 EEEQGEEKEKGAQEKR---RGKRVR-----FAEDEEKSENSSEDGDITDKSLCGSGEKYI 339
E++ +++EK +E+R R K++R E EEK + E ++ + EK
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ 605
Query: 340 PPHVRQAEETVDFKKKEELERLKK 363
+ E+ ++EE +++++
Sbjct: 606 EQEEKMWEQEEKMWEQEEEDKMQE 629
Score = 37.7 bits (86), Expect = 0.046
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 262 EEEGDVEKEKKAQEAEAQSEDDDEDTEEEQG----EEKEKGAQEKRRGKRVRFAEDEEKS 317
++E + +EKK QE E ++ D +E EE+ E+K + +E R + + E EEK
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 318 ENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELERL 361
E ++ + EK + E+ + K +E+ E +
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM 634
Score = 37.0 bits (84), Expect = 0.078
Identities = 25/114 (21%), Positives = 57/114 (50%), Gaps = 5/114 (4%)
Query: 256 QDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEE 315
Q++ E+E ++ ++KK +E E Q ++ +E E+ EEK + +EK + R E E+
Sbjct: 288 QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQ--EEKMREQEEKMWRQEERLWEQEK 345
Query: 316 KSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEEL---ERLKKHVK 366
+ + ++ + E+ R E+ ++++E++ ER+++ K
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Score = 36.2 bits (82), Expect = 0.13
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 256 QDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEE 315
Q+E +EE E+EKK ++ E + +E E++G+ +E+ + +R+ KR+R ++E
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR---EQE 289
Query: 316 KSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
K E K L E+ + E+ +++EE
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Score = 36.2 bits (82), Expect = 0.13
Identities = 35/169 (20%), Positives = 77/169 (45%), Gaps = 11/169 (6%)
Query: 224 ESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDD 283
E K + + EEE + + E + E EE+ + EK ++ +E + E+
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 284 DEDTEEEQGEEKEK----GAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYI 339
++ EE+ E++EK ++K + + E EEK + E ++ + EK
Sbjct: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK-- 661
Query: 340 PPHVRQAEETVDFKKKEELERLKKHVKGLLNRLSEPNMASISGQLEELY 388
+R+ EE + ++E++ ++ ++G ++ E + GQ E+++
Sbjct: 662 ---MREQEEKMQ-GQEEKMREQEEKMQGQEEKMREQE-EKMRGQEEKMW 705
Score = 35.4 bits (80), Expect = 0.23
Identities = 37/181 (20%), Positives = 80/181 (44%), Gaps = 5/181 (2%)
Query: 179 NEEEDREIRKLERCLGLNKRKKKDGSSSVP-LSFARDGLDYILGALESGKNSGLYDSSGE 237
NEE ++ +L+ L L + +K + +V L + ++L +++ E
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 238 EEEDAGQTLPESDLESDSQDESEEEEEGDV-EKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
E + + + + + + Q+E E+EG + E+E+K + E + + +++ E+ EKE
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ---EKE 298
Query: 297 KGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKE 356
Q+K R + + E EEK E ++ + E+ + E+ + +E
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 357 E 357
E
Sbjct: 359 E 359
Score = 33.9 bits (76), Expect = 0.66
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 25/136 (18%)
Query: 238 EEEDAGQTLPESDLESDSQDESEEE-----EEGDVEKEKKAQEAEAQSEDDDEDTEEEQG 292
E+E+ Q E E + + +EE EE E+EK+ +E E + D +E E+
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 293 EEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDF 352
+EK E+R ++ + E EEK + E+ I ++ +R+ EET+
Sbjct: 367 RLREK---EERMREQEKMWEQEEKMQ---EEERIRERE----------KKMREEEETM-- 408
Query: 353 KKKEELERLKKHVKGL 368
+E+ E+++K + +
Sbjct: 409 --REQEEKMQKQEENM 422
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 10/90 (11%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEE------ 290
++ D + + E D ++E E+E E+E+K QE E E + + EEE
Sbjct: 352 QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQ 411
Query: 291 ----QGEEKEKGAQEKRRGKRVRFAEDEEK 316
Q +E+ QE++ ++ R E +EK
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Score = 31.6 bits (70), Expect = 3.3
Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 256 QDESEEEEEGDVEKEKKAQEAEAQSEDDDE----------DTEEEQGEEKEKGAQEKRRG 305
Q++ E+E+ E+E+K ++ E + D +E + EE E+K+ QE++
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 306 KRVRFAEDEEKSENSSE 322
+ + E E+K+ + E
Sbjct: 538 EEKKTQEQEKKTWDQEE 554
Score = 30.4 bits (67), Expect = 7.3
Identities = 25/122 (20%), Positives = 54/122 (44%), Gaps = 4/122 (3%)
Query: 238 EEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDE--DTEEEQGEEK 295
E+ED Q + + D + + ++EE E++++ +E E + + + EE+ EEK
Sbjct: 483 EQED--QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 296 EKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKK 355
+ QEK+ + +EE+ + ++ + EK + E+ ++
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 356 EE 357
EE
Sbjct: 601 EE 602
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 56.2 bits (134), Expect = 1e-07
Identities = 34/104 (32%), Positives = 55/104 (52%)
Query: 238 EEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEK 297
EE+ + SD E + ++E EEEEE + E+E+ +E E E+ E+ EEE+ E +E+
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 298 GAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPP 341
+E+ + EDEE+ E E D+ + G E+ PP
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPP 978
Score = 50.1 bits (118), Expect = 9e-06
Identities = 25/74 (33%), Positives = 45/74 (60%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKE 296
EEEE+ + E + E D ++E E+EEE E+E++ +E E + E+++ + EEE+ EE E
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
Query: 297 KGAQEKRRGKRVRF 310
+ +E + + F
Sbjct: 952 EEEEELEEVEDLEF 965
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 59/115 (51%), Gaps = 28/115 (24%)
Query: 248 ESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKR 307
E DL + + S+EEEE + E+E E E + E+++ED EEE+ +E+E +E+
Sbjct: 875 EEDLTVININSSDEEEEEEEEEE----EEEEEEEEEEEDFEEEEEDEEEYFEEEEEE--- 927
Query: 308 VRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEELERLK 362
E+E + E E+G++ ++ EE D +++EELE ++
Sbjct: 928 ----EEEFEEEFEEEEGELEEE-----------------EEEEDEEEEEELEEVE 961
Score = 37.7 bits (86), Expect = 0.046
Identities = 41/183 (22%), Positives = 74/183 (40%), Gaps = 38/183 (20%)
Query: 123 RQDTEER-ARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLA---A 178
+++ EE A P P P PP P P V + P A + + +
Sbjct: 826 KEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININS 885
Query: 179 NEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEE 238
++EE+ E + E + +++D ++ E+
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEED-----------------------------FEEEEED 916
Query: 239 EEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSE-DDDEDTE-EEQGEEKE 296
EE + E + E + +E EEEEG++E+E++ ++ E + E ++ ED E G E E
Sbjct: 917 EE---EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973
Query: 297 KGA 299
+GA
Sbjct: 974 EGA 976
Score = 30.8 bits (68), Expect = 5.6
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 237 EEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQ-EAEAQSEDDDEDT 287
EEE A TL E + E D D+ + E E+E + + EAEA E + +DT
Sbjct: 1055 EEEPSAPPTLLEEETE-DGSDKVQPPPETPAEEEMETETEAEALQEKEQDDT 1105
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 56.2 bits (134), Expect = 1e-07
Identities = 59/242 (24%), Positives = 102/242 (42%), Gaps = 40/242 (16%)
Query: 112 GRSGAEEASGHRQDTEERARPAPSRDPSPPRKPRPSRVKA---KATAATAKTRPSAAATA 168
G+ GAEE H E R +P R SP R PR SR ++ + +++ R
Sbjct: 244 GKEGAEEIDRH---VERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE 300
Query: 169 AARKRALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKN 228
R E+E R R ++R GL +R+ + S +RD G
Sbjct: 301 RQRLEREAKEREKERRRSRSIDR--GLERRRSRSRERHRSRSRSRD---------RKGDR 349
Query: 229 SGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEE------------GDVEKEK-KAQE 275
D E+E + G+ + D + + +E E+E E G+VE++K K +
Sbjct: 350 RDR-DREREKENERGRRR-DRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407
Query: 276 AEAQSEDDDEDTEEEQGEEKEKGAQEKRR--------GKRVRFAEDEEKSENSSEDGDIT 327
+ + DD D+++E+ + + + K R GKR R E+ S++ +E + +
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467
Query: 328 DK 329
+K
Sbjct: 468 NK 469
Score = 40.4 bits (93), Expect = 0.007
Identities = 43/214 (20%), Positives = 88/214 (41%), Gaps = 33/214 (15%)
Query: 78 GRKSRKELRKEKRHLR-KARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSR 136
GR+ ++ KE+ + R K R R EQ G E H++D ++R R
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRS-----RGEVEEKKHKEDKDDRRHRDDKR 417
Query: 137 DPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDREIRKLERCLGLN 196
D +K SR + + + +++R +A + +R + + ++ E +E
Sbjct: 418 DSKKEKKHSRSRSRERKHRSRSRSR-NAGKRSRSRSKEKSSKHKNESKE----------- 465
Query: 197 KRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQ 256
K K+ S S G +S + S + S +E+ ++ S S +
Sbjct: 466 KSNKRSRSGS-------------QGRTDSVEKSKKREHSPSKEKSRKRS--RSKERSHKR 510
Query: 257 DESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEE 290
D S+ +++ D +++Q E +S++ ++E
Sbjct: 511 DHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 32.0 bits (71), Expect = 2.5
Identities = 56/275 (20%), Positives = 103/275 (37%), Gaps = 32/275 (11%)
Query: 66 EGRGAPVSFRPGGR-KSRKELRKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQ 124
EG G+ R R K R+ L +E + K RR R+ GL R + HR
Sbjct: 284 EGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDR----GLERRR-SRSRERHRS 338
Query: 125 DTEERARPAPSRDPSPPRKPRPSRV--------KAKATAATAKTRPSAAATAAARKRALL 176
+ R R RD R+ R K + + S + R R +
Sbjct: 339 RSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEV 398
Query: 177 AANE-EEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSS 235
+ +ED++ R+ +K++KK S R + +N+G S
Sbjct: 399 EEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR--------SRSRSRNAGKRSRS 450
Query: 236 GEEEEDAGQTLPESDLESDSQDESEEEEEGD-VEKEKKAQEAEAQSEDDDEDTEEEQGEE 294
+E+ + ES +S+ + S + D VEK KK + + ++ + +E+ +
Sbjct: 451 RSKEKSSKHK-NESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHK 509
Query: 295 K-------EKGAQEKRRGKRVRFAEDEEKSENSSE 322
+ + ++RR + + E++ +N E
Sbjct: 510 RDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 55.1 bits (131), Expect = 3e-07
Identities = 41/147 (27%), Positives = 76/147 (51%), Gaps = 16/147 (10%)
Query: 233 DSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQG 292
DS GEE+E ++L E ++ ++E+EEEEE + + + + + + +SE+DDEDT +
Sbjct: 1030 DSGGEEDEK--ESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRD-ESENDDEDTALSEA 1086
Query: 293 EEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDF 352
EK++G ++ + ++ E S + S + + S S P + EE V
Sbjct: 1087 SEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESS------PSSSEDEEEVVA 1140
Query: 353 KKKEELERLKKHVKGLLNRLSEPNMAS 379
+++EE E ++ V +E +MAS
Sbjct: 1141 REEEEEEEEEEMV-------AEESMAS 1160
Score = 37.4 bits (85), Expect = 0.060
Identities = 40/179 (22%), Positives = 71/179 (39%), Gaps = 4/179 (2%)
Query: 127 EERARPAPSRDPSPPRKPRP-SRVKAKATAATAKTRPSAAATAAARKRALLAANEEEDRE 185
++R RP+ S D R R A AK P R L + E+ E
Sbjct: 978 QKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDE 1037
Query: 186 IRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQT 245
L + +++ D D + +++ L ++S ++E D+ +
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE 1097
Query: 246 LPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDE---DTEEEQGEEKEKGAQE 301
S + S ++ S E E E ++ + + SED++E EEE+ EE+E A+E
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEE 1156
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 54.7 bits (130), Expect = 4e-07
Identities = 24/71 (33%), Positives = 45/71 (63%)
Query: 231 LYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEE 290
L D++ EE L + + + ++E EEEEE + E+E++ +E E + E+++E+ EEE
Sbjct: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299
Query: 291 QGEEKEKGAQE 301
+ EE+E+ A +
Sbjct: 300 EEEEEEEAAPD 310
Score = 52.4 bits (124), Expect = 2e-06
Identities = 24/76 (31%), Positives = 47/76 (61%)
Query: 238 EEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEK 297
E+ + ++ + + S +++ EEEEE + E+E + +E E + E+++E+ EEE+ EE+E+
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 298 GAQEKRRGKRVRFAED 313
+E+ V F ED
Sbjct: 301 EEEEEEAAPDVIFQED 316
Score = 48.5 bits (114), Expect = 3e-05
Identities = 61/225 (27%), Positives = 101/225 (44%), Gaps = 36/225 (16%)
Query: 111 GGRSGAE-EASG----HRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAA 165
G GAE E SG HR +T E P S S P +ATA ++ S +
Sbjct: 110 GTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNP-----------IGSATASSKGSYS 158
Query: 166 ATAAARKRALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPL-SFARDGLDYILGALE 224
+ +LL + + + +E LG + K G V L A +G A E
Sbjct: 159 SYQGIIATSLLNLGQIAEETL--VEEDLG---QAAKPGPGIVHLLQEAAEG-----AASE 208
Query: 225 SGKNSGLYDSSGEEEE------DAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEA 278
G+ GL+ + EE + Q L LE D+ E +++G + E++ +E E
Sbjct: 209 EGEK-GLFIQPEDAEEVVEVTTERSQDLCPQSLE-DAASEESSKQKGILSHEEEDEEEE- 265
Query: 279 QSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSED 323
+ E+++E+ EEE+ EE+E+ +E+ + E+EE+ E ++ D
Sbjct: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 14/121 (11%)
Query: 224 ESGKNSGLY---DSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQS 280
ES K G+ + EEEE+ + + + E + ++E EEEEE + E+E++ +E E +
Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Query: 281 EDDDEDTEEEQGEEKEKGAQEKRRGKR----------VRFAEDEEKSENS-SEDGDITDK 329
D +E+ + A E R + V D++K E++ S +TD+
Sbjct: 307 AAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDE 366
Query: 330 S 330
S
Sbjct: 367 S 367
Score = 32.7 bits (73), Expect = 1.5
Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 20/111 (18%)
Query: 228 NSGLYDSSGEEEEDAGQ-----TLPESDLESDSQDESEEEEEGDVE---------KEKKA 273
+S S G + DA Q + P S + S ++ ++E D +E++
Sbjct: 686 SSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEP 745
Query: 274 QEAE------AQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSE 318
+E+E A SE DD++ EE EE++ + +++F + K E
Sbjct: 746 EESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKE 796
Score = 30.8 bits (68), Expect = 5.6
Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 6/125 (4%)
Query: 239 EEDAGQTLPESD------LESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQG 292
EED GQ E+ SEE E+G + + A+E + + +D +
Sbjct: 181 EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240
Query: 293 EEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDF 352
E+ K++G EDEE+ E E+ + ++ E+ + EE +
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 353 KKKEE 357
+++EE
Sbjct: 301 EEEEE 305
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 54.7 bits (130), Expect = 4e-07
Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 8/161 (4%)
Query: 185 EIRKLERCLGLNKRKKKDGSSSVPLSFARDGL----DYILGALESGKNSGLYDSSGEEEE 240
E+ L R LNK +K++ + L + DY E + D +E+
Sbjct: 53 ELSSLARLPSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDN 112
Query: 241 DAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDED-TEEEQGEEKEKGA 299
+A + E D + D DE EEE E + + +E E + ED+DED E+E G E +G
Sbjct: 113 EAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGE 172
Query: 300 QEKRRGKRVR-FAEDEEKSENSSEDGDITDKSLCGS--GEK 337
+E ++ +DEE ++ E+G+ ++ G GEK
Sbjct: 173 EEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEK 213
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/111 (31%), Positives = 52/111 (46%), Gaps = 18/111 (16%)
Query: 224 ESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEA------- 276
E G D EEE +AG P E + ++E EE+E+ D ++++ E
Sbjct: 119 EEDDEDGDEDDEEEEENEAG---PPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175
Query: 277 --------EAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSEN 319
E Q E+DD+D EE EE+E+ R KR R AED+ + E+
Sbjct: 176 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
Score = 37.0 bits (84), Expect = 0.078
Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 9/59 (15%)
Query: 236 GEEEEDAGQT-LPESDLESDSQD--------ESEEEEEGDVEKEKKAQEAEAQSEDDDE 285
GE EE+ G + L + +++ + D E EEEEEG + EK+ ++AE E++D+
Sbjct: 169 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 53.9 bits (128), Expect = 6e-07
Identities = 25/82 (30%), Positives = 51/82 (62%), Gaps = 2/82 (2%)
Query: 244 QTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQS--EDDDEDTEEEQGEEKEKGAQE 301
Q P+SD + D D+ EE+EEG+ EK+ + ++ E + E++DED + E ++K++ ++E
Sbjct: 173 QEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEE 232
Query: 302 KRRGKRVRFAEDEEKSENSSED 323
+ + +DE++ E+ E+
Sbjct: 233 EEEFGLDKDEDDEDEDEDEEEE 254
Score = 50.8 bits (120), Expect = 5e-06
Identities = 30/84 (35%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Query: 233 DSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQG 292
D GE+E+D E + E D +++ +E+ EGD +K++ ++E E D DED E+E
Sbjct: 191 DEEGEDEKDXENEDGEEE-ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDE 249
Query: 293 EEKEKGAQEKRRGK-RVRFAEDEE 315
+E+E +E +G+ R R +DEE
Sbjct: 250 DEEE---EESGKGENRKRETDDEE 270
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 9/96 (9%)
Query: 232 YDSSGEEEEDAGQTLPESDLESDSQ---DESEEEEEGDVEKEKKAQEAEAQSEDDDEDTE 288
YD +E D+ + D E + + DE + E E E+E +E E + + D+D +
Sbjct: 168 YDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKD 227
Query: 289 EEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDG 324
E EE+E G + EDE++ E E G
Sbjct: 228 EVSEEEEEFGLDKDEDD------EDEDEDEEEEESG 257
Score = 40.8 bits (94), Expect = 0.005
Identities = 41/169 (24%), Positives = 69/169 (40%), Gaps = 31/169 (18%)
Query: 193 LGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSS----GEEEEDAGQTLPE 248
L L+ +K KD S+ PL LE K+ L++ + +E + LP+
Sbjct: 113 LNLSGKKLKDISTLEPLK-----------KLECLKSLDLFNCEVINLNDYQESVFKLLPQ 161
Query: 249 SDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKGAQEKRRGKRV 308
E +E + D + + +E E + +D++D E E GEE+E
Sbjct: 162 LTCLDTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEEL----------- 210
Query: 309 RFAEDEEKSENSSEDGDITDKSLCGSGEKYIPPHVRQAEETVDFKKKEE 357
DEE+ E+ +GD DK E+ + +E D ++EE
Sbjct: 211 ----DEEEDEDEDVEGD-DDKDEVSEEEEEFGLDKDEDDEDEDEDEEEE 254
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,531,114
Number of Sequences: 37866
Number of extensions: 1778148
Number of successful extensions: 43470
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 741
Number of HSP's successfully gapped in prelim test: 1253
Number of HSP's that attempted gapping in prelim test: 15421
Number of HSP's gapped (non-prelim): 12540
length of query: 860
length of database: 18,247,518
effective HSP length: 111
effective length of query: 749
effective length of database: 14,044,392
effective search space: 10519249608
effective search space used: 10519249608
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.