Search of human proteins with 60593095

Search of human proteins with 60593095

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|60593095 GRAM domain containing 2 [Homo sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|60593095 GRAM domain containing 2 [Homo sapiens]                   731   0.0  
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]        140   1e-33
gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]        140   1e-33
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]        140   1e-33
gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]        140   1e-33
gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]        140   1e-33
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]        92   7e-19
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]         92   7e-19
gi|144227752 GRAM domain containing 1B [Homo sapiens]                  92   7e-19
gi|187936935 GRAM domain containing 1C [Homo sapiens]                  90   3e-18
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho...    57   3e-08
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso...    55   7e-08
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso...    55   7e-08
gi|67763814 death-inducing-protein [Homo sapiens]                      50   3e-06
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               47   3e-05
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso...    40   0.004
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso...    40   0.004
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]                   34   0.23 
gi|238859651 pleckstrin homology domain containing family A memb...    33   0.39 
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  33   0.39 
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    33   0.51 
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    33   0.51 
gi|83367077 mucin 16 [Homo sapiens]                                    32   0.86 
gi|118026942 zinc finger protein Cezanne [Homo sapiens]                32   0.86 
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    32   0.86 
gi|7662470 neuroligin 1 [Homo sapiens]                                 32   1.1  
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    32   1.1  
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int...    31   1.5  
gi|7662354 MON1 homolog B [Homo sapiens]                               31   1.5  
gi|146134388 YLP motif containing 1 [Homo sapiens]                     31   1.5  

>gi|60593095 GRAM domain containing 2 [Homo sapiens]
          Length = 354

 Score =  731 bits (1887), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MTALSRSEATEEGGNQQMHRKTASLNSPVSCKEKPDRVEEPPDYSLHWPEGLKGEEIKKC 60
           MTALSRSEATEEGGNQQMHRKTASLNSPVSCKEKPDRVEEPPDYSLHWPEGLKGEEIKKC
Sbjct: 1   MTALSRSEATEEGGNQQMHRKTASLNSPVSCKEKPDRVEEPPDYSLHWPEGLKGEEIKKC 60

Query: 61  GREGITLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFG 120
           GREGITLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFG
Sbjct: 61  GREGITLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFG 120

Query: 121 KDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHL 180
           KDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHL
Sbjct: 121 KDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHL 180

Query: 181 QPSSKKSLSVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSSVDSTDSFF 240
           QPSSKKSLSVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSSVDSTDSFF
Sbjct: 181 QPSSKKSLSVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSSVDSTDSFF 240

Query: 241 PSRKPPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPR 300
           PSRKPPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPR
Sbjct: 241 PSRKPPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPR 300

Query: 301 STGELRLWDYRLLKVFFVLICFLVMSSSYLAFRISRLEQQLCSLSWDDPVPGHR 354
           STGELRLWDYRLLKVFFVLICFLVMSSSYLAFRISRLEQQLCSLSWDDPVPGHR
Sbjct: 301 STGELRLWDYRLLKVFFVLICFLVMSSSYLAFRISRLEQQLCSLSWDDPVPGHR 354


>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
          Length = 416

 Score =  140 bits (354), Expect = 1e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 91  KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 150

Query: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 151 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 208

Query: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 209 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 258

Query: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 259 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 318

Query: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 319 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 359


>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
          Length = 440

 Score =  140 bits (354), Expect = 1e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 115 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 174

Query: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 175 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 232

Query: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 233 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 282

Query: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 283 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 342

Query: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 343 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 383


>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
          Length = 328

 Score =  140 bits (354), Expect = 1e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 3   KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 62

Query: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 63  AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 120

Query: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 121 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 170

Query: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 171 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 230

Query: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 231 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 271


>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
          Length = 447

 Score =  140 bits (354), Expect = 1e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 181

Query: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 182 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 239

Query: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 240 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 289

Query: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 290 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 349

Query: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 350 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 390


>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
          Length = 432

 Score =  140 bits (354), Expect = 1e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 166

Query: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 167 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 224

Query: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 225 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 274

Query: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 275 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 334

Query: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 335 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 375


>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
          Length = 713

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 50/127 (39%), Positives = 79/127 (62%), Gaps = 3/127 (2%)

Query: 66  TLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKV 125
           T  + N+ + KLF  +P  E ++   SCALQR+ LLQGRLY+S NW+CF++++F  +  +
Sbjct: 78  TYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTI 137

Query: 126 VIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSK 185
            I +  V  +KK K A+L+PN + I T  S+K+ F S  +RD  + L+ R+  +     +
Sbjct: 138 SIQLKEVTCLKKEKTAKLIPNAIQICTE-SEKHFFTSFGARDRCFLLIFRLWQN--ALLE 194

Query: 186 KSLSVRE 192
           K+LS RE
Sbjct: 195 KTLSPRE 201


>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
          Length = 724

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 50/127 (39%), Positives = 79/127 (62%), Gaps = 3/127 (2%)

Query: 66  TLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKV 125
           T  + N+ + KLF  +P  E ++   SCALQR+ LLQGRLY+S NW+CF++++F  +  +
Sbjct: 85  TYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTI 144

Query: 126 VIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSK 185
            I +  V  +KK K A+L+PN + I T  S+K+ F S  +RD  + L+ R+  +     +
Sbjct: 145 SIQLKEVTCLKKEKTAKLIPNAIQICTE-SEKHFFTSFGARDRCFLLIFRLWQN--ALLE 201

Query: 186 KSLSVRE 192
           K+LS RE
Sbjct: 202 KTLSPRE 208


>gi|144227752 GRAM domain containing 1B [Homo sapiens]
          Length = 738

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 44/111 (39%), Positives = 72/111 (64%), Gaps = 1/111 (0%)

Query: 66  TLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKV 125
           T  + N+ + KLFK +P  E ++   SCALQRD LLQGRLY+S NW+CF++++F  +  +
Sbjct: 90  TYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLL 149

Query: 126 VIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRV 176
            + +  +  + K K ARL+PN + + T+ S+K+ F S  +RD  Y ++ R+
Sbjct: 150 TVRLKDICSMTKEKTARLIPNAIQVCTD-SEKHFFTSFGARDRTYMMMFRL 199


>gi|187936935 GRAM domain containing 1C [Homo sapiens]
          Length = 662

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 49/128 (38%), Positives = 78/128 (60%), Gaps = 3/128 (2%)

Query: 66  TLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKV 125
           T    N++Y + F  +P  E ++   +CALQRD LLQGRLY+S NWLCF++++F  +  +
Sbjct: 63  TYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTI 122

Query: 126 VIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSK 185
            I + ++  + K K ARL+PN + I T  S+K+ F S  +RD  Y  + R+  ++     
Sbjct: 123 SIALKNITFMTKEKTARLIPNAIQIVTE-SEKFFFTSFGARDRSYLSIFRLWQNV--LLD 179

Query: 186 KSLSVREF 193
           KSL+ +EF
Sbjct: 180 KSLTRQEF 187


>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
           sapiens]
          Length = 1266

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 51/209 (24%), Positives = 96/209 (45%), Gaps = 25/209 (11%)

Query: 71  NQQYHKLFKDVPLEEVVLKVCSCALQRDFL---LQGRLYISPNWLCFHASLFGKDIKVVI 127
           +++Y  LF+ +P +E +     C L   F    + G++++S N++CF  S       ++I
Sbjct: 292 SERYRALFR-LPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICF-TSKEENLCSLII 349

Query: 128 PVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKS 187
           P+  V +++K   + +LP+ L+I+T     ++F +L  RD    L++R+   LQ ++ K 
Sbjct: 350 PLREVTIVEKADSSSVLPSPLSISTRNRMTFLFANLKDRDF---LVQRISDFLQQTTSKI 406

Query: 188 LSVREFSG-----------EPESLEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSSVDST 236
            S +EF+G            P SL    P+          R  +L  N     P++  + 
Sbjct: 407 YSDKEFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGN---SVPTATQTL 463

Query: 237 DSFFPSRKPPMSEKSRAQVASENGGRWAW 265
            + +  R P   E+   ++A E     AW
Sbjct: 464 MTMYRRRSP---EEFNPKLAKEFLKEQAW 489



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 30/92 (32%), Positives = 57/92 (61%), Gaps = 3/92 (3%)

Query: 73  QYHKLFKDVPLEEVVLKVCSCALQRDFL-LQGRLYISPNWLCFHASLFGKDIKVVIPVVS 131
           ++H+LF  +P EE ++   SC+  +  +  QG +Y+S N LCF++ L G++ K+VI  V 
Sbjct: 147 KFHRLF-GMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKLVIRWVD 205

Query: 132 VQMIKKHKMARLLPNGLAITTNTSQKYIFVSL 163
           +  ++K+    LLP+ + ++T +S+ +  V L
Sbjct: 206 ITQLEKN-ATLLLPDVIKVSTRSSEHFFSVFL 236


>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 1233

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 24/185 (12%)

Query: 71  NQQYHKLFKDVPLEEVVLKVCSCALQRDFL---LQGRLYISPNWLCFHASLFGKDIKVVI 127
           N+ Y   F+ +P +E +    SC L   F    + G+++IS N++CF AS       ++I
Sbjct: 287 NECYRATFR-LPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICF-ASKEEDACHLII 344

Query: 128 PVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKS 187
           P+  V +++K   + +LP+ L+I+T +   ++F +L  RD    L++R+   LQ +  K 
Sbjct: 345 PLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPSK- 400

Query: 188 LSVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLP---DNIPCIPPSSVDSTDSFFPSRK 244
                   +P S    I   K   V PS+ S   P      P  P S + S  SF     
Sbjct: 401 --------QPGS----IGSRKASVVDPSTESSPAPQEGSEQPASPASPLSSRQSFCAQEA 448

Query: 245 PPMSE 249
           P  S+
Sbjct: 449 PTASQ 453



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 6/130 (4%)

Query: 51  GLKGEEIKKCGREGIT-LNKYNQQYHKLFKD--VPLEEVVLKVCSCALQRDFL-LQGRLY 106
           G+  EE K    +G     K+ +   K+ K   +P  E ++   SC+  +  +  QG LY
Sbjct: 117 GIIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYYSCSYWKGRVPRQGWLY 176

Query: 107 ISPNWLCFHASLFGKDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSR 166
           ++ N LCF++ L GK++ +V+  V +  ++K+    L P  + + T   Q+  F   L+ 
Sbjct: 177 LTVNHLCFYSFLLGKEVSLVVQWVDITRLEKN-ATLLFPESIRVDTR-DQELFFSMFLNI 234

Query: 167 DSVYDLLRRV 176
              + L+ ++
Sbjct: 235 GETFKLMEQL 244


>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1250

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 24/185 (12%)

Query: 71  NQQYHKLFKDVPLEEVVLKVCSCALQRDFL---LQGRLYISPNWLCFHASLFGKDIKVVI 127
           N+ Y   F+ +P +E +    SC L   F    + G+++IS N++CF AS       ++I
Sbjct: 287 NECYRATFR-LPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICF-ASKEEDACHLII 344

Query: 128 PVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKS 187
           P+  V +++K   + +LP+ L+I+T +   ++F +L  RD    L++R+   LQ +  K 
Sbjct: 345 PLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPSK- 400

Query: 188 LSVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLP---DNIPCIPPSSVDSTDSFFPSRK 244
                   +P S    I   K   V PS+ S   P      P  P S + S  SF     
Sbjct: 401 --------QPGS----IGSRKASVVDPSTESSPAPQEGSEQPASPASPLSSRQSFCAQEA 448

Query: 245 PPMSE 249
           P  S+
Sbjct: 449 PTASQ 453



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 6/130 (4%)

Query: 51  GLKGEEIKKCGREGIT-LNKYNQQYHKLFKD--VPLEEVVLKVCSCALQRDFL-LQGRLY 106
           G+  EE K    +G     K+ +   K+ K   +P  E ++   SC+  +  +  QG LY
Sbjct: 117 GIIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYYSCSYWKGRVPRQGWLY 176

Query: 107 ISPNWLCFHASLFGKDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSR 166
           ++ N LCF++ L GK++ +V+  V +  ++K+    L P  + + T   Q+  F   L+ 
Sbjct: 177 LTVNHLCFYSFLLGKEVSLVVQWVDITRLEKN-ATLLFPESIRVDTR-DQELFFSMFLNI 234

Query: 167 DSVYDLLRRV 176
              + L+ ++
Sbjct: 235 GETFKLMEQL 244


>gi|67763814 death-inducing-protein [Homo sapiens]
          Length = 578

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 34/116 (29%), Positives = 65/116 (56%), Gaps = 17/116 (14%)

Query: 74  YHKLFKDVPLEEVVLKVCS-----CALQRD------FLLQGRLYISPNWLCFHASLFGKD 122
           +H++F ++   E  L VC      C + RD      ++  G LY++ N+LCF +S  G  
Sbjct: 447 FHEIF-NLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSS 505

Query: 123 IK-VVIPVVSVQMIKKHKMARLLPN---GLAITTNTSQK-YIFVSLLSRDSVYDLL 173
            +  VI +V +  I+K+K+  +LP    G+A++T ++QK  +F +++ RD  ++ +
Sbjct: 506 KRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETI 561


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 2/93 (2%)

Query: 84  EEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIPVVSVQMIKKHKMARL 143
           E++V     C  +     QG LY+S N LCF++   GK++K+V+P V +Q +++      
Sbjct: 157 EKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNV-F 215

Query: 144 LPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRV 176
           L + + ITT   ++  F   L+ D V+ ++ ++
Sbjct: 216 LTDTIRITTQNKER-DFSMFLNLDEVFKVMEQL 247



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 4/104 (3%)

Query: 73  QYHKLFKDVPLEEVVLKVCSCALQRDFL---LQGRLYISPNWLCFHASLFGKDIKVVIPV 129
           ++ + F  +P +E +  V  C+L   F      GR++ S +++CF AS      K+++P+
Sbjct: 285 EFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICF-ASREDGCCKIILPL 343

Query: 130 VSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLL 173
             V  I+K +   LLP+ + ++  +   + F+ L  RDS+ + L
Sbjct: 344 REVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDSLVEAL 387


>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 632

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 51  GLKGEEIKKCGREGITLNKYNQQYHKLFK--DVPLEEVVLKVCSCALQRDFL-LQGRLYI 107
           GL  EE K C  +     K+ +   K  K   +P +E ++   SC+  +  +  QG LY+
Sbjct: 121 GLIAEEGKHCFAKEDDPEKFREALLKFEKCFGLPEKEKLVTYYSCSYWKGRVPCQGWLYL 180

Query: 108 SPNWLCFHASLFGKDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRD 167
           S N+L F++ L G +IK++I    V  ++K     +L   + + +     Y F   L  +
Sbjct: 181 STNFLSFYSFLLGSEIKLIISWDEVSKLEKTSNV-ILTESIHVCSQGENHY-FSMFLHIN 238

Query: 168 SVYDLLRRVCTH 179
             Y L+ ++  +
Sbjct: 239 QTYLLMEQLANY 250


>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1120

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 51  GLKGEEIKKCGREGITLNKYNQQYHKLFK--DVPLEEVVLKVCSCALQRDFL-LQGRLYI 107
           GL  EE K C  +     K+ +   K  K   +P +E ++   SC+  +  +  QG LY+
Sbjct: 121 GLIAEEGKHCFAKEDDPEKFREALLKFEKCFGLPEKEKLVTYYSCSYWKGRVPCQGWLYL 180

Query: 108 SPNWLCFHASLFGKDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRD 167
           S N+L F++ L G +IK++I    V  ++K     +L   + + +     Y F   L  +
Sbjct: 181 STNFLSFYSFLLGSEIKLIISWDEVSKLEKTSNV-ILTESIHVCSQGENHY-FSMFLHIN 238

Query: 168 SVYDLLRRVCTH 179
             Y L+ ++  +
Sbjct: 239 QTYLLMEQLANY 250


>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
          Length = 398

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 15/84 (17%)

Query: 214 PSSRSLSLPDNIPCI--PP------SSVDSTDSFFPSRKPPMSEKSRAQVASENGGRWAW 265
           P  R+LS     P +  PP      S+  S  S      PP +  SRA+ +S+ G RW  
Sbjct: 284 PLGRNLSTHQTYPVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQ-GERW-- 340

Query: 266 PMPGWGPACPKKMPNCSPTAKNAV 289
               WGP CP   P   P  + A+
Sbjct: 341 ----WGPRCPDTHPTSPPADRAAM 360


>gi|238859651 pleckstrin homology domain containing family A member
           4 isoform 1 [Homo sapiens]
          Length = 779

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 2/67 (2%)

Query: 208 KWRKVCPSSRSLSLPDNIPCIP-PSSVDSTDSFFPSRKPPMSEKSRAQVASENGGRWAWP 266
           +W ++       S  D +P +P P S  +     P R PP++       +    GR   P
Sbjct: 686 QWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPPPRSPPVANSGSTGFSRRGSGRGGGP 745

Query: 267 MPGWGPA 273
            P WGPA
Sbjct: 746 TP-WGPA 751


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 3/77 (3%)

Query: 226 PCIPPSSVDSTDSFFPSRKPPMSEKSRAQVASENGGRWAWPMP---GWGPACPKKMPNCS 282
           P    + V  T    P  + PMS +S  Q  +  G  +  P P     GPA P   P   
Sbjct: 797 PAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPV 856

Query: 283 PTAKNAVYEEDELEEEP 299
           PTA   +    E + EP
Sbjct: 857 PTAVPTLCLPPEADAEP 873


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 31/125 (24%), Positives = 49/125 (39%), Gaps = 8/125 (6%)

Query: 143 LLPNGLAITTNTSQKYIFVS---LLSRDSVYDLLRRVCTHLQPSSKKSLSVREFSGEPES 199
           L P+   I T +S   +  S   +L+R S   L       L PSS  +L+         S
Sbjct: 144 LTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPS 203

Query: 200 LEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSS-----VDSTDSFFPSRKPPMSEKSRAQ 254
              ++       + PSSR +  P + P + PSS       ST +  PS  P ++  +   
Sbjct: 204 SRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPT 263

Query: 255 VASEN 259
           +   N
Sbjct: 264 LTPSN 268


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 31/125 (24%), Positives = 49/125 (39%), Gaps = 8/125 (6%)

Query: 143 LLPNGLAITTNTSQKYIFVS---LLSRDSVYDLLRRVCTHLQPSSKKSLSVREFSGEPES 199
           L P+   I T +S   +  S   +L+R S   L       L PSS  +L+         S
Sbjct: 144 LTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPS 203

Query: 200 LEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSS-----VDSTDSFFPSRKPPMSEKSRAQ 254
              ++       + PSSR +  P + P + PSS       ST +  PS  P ++  +   
Sbjct: 204 SRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPT 263

Query: 255 VASEN 259
           +   N
Sbjct: 264 LTPSN 268


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 31/151 (20%)

Query: 119  FGKDIKVVIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCT 178
            F +  KV+ PVV+   I+ + ++  +P    IT         + + S  S          
Sbjct: 9539 FSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITR--------IEIESMSS---------- 9580

Query: 179  HLQPSSKKSLSVREFSGEPESLEVL-------IPEMKWRKVCPSSRSLSLPDNIPCIPPS 231
             L P  +++ + ++ +   E+  VL        PE+   +V PSSR+ S+P   P     
Sbjct: 9581 -LTPGLRETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRT-SIPG--PAQSTM 9636

Query: 232  SVDSTDSFFP--SRKPPMSEKSRAQVASENG 260
            S+D +D      S  P M+E +   + ++ G
Sbjct: 9637 SLDISDEVVTRLSTSPIMTESAEITITTQTG 9667


>gi|118026942 zinc finger protein Cezanne [Homo sapiens]
          Length = 843

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 37/130 (28%), Positives = 48/130 (36%), Gaps = 19/130 (14%)

Query: 191 REFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSSVDSTDSFFPSRKPPMSEK 250
           R+ +G P  +  L P   + + CP  R     D+IP + P S         +  PP    
Sbjct: 713 RQLAGGP-CVGGLPPYATFPRQCPPGRPYPHQDSIPSLEPGSHSKDGLHRGALLPP---P 768

Query: 251 SRAQVASENGGR-------WAWPMPGWGPACPK-KMPNCS----PTAKN---AVYEEDEL 295
            R   +  NG R       WA  + G  P   K K PNCS    P   N     Y E+  
Sbjct: 769 YRVADSYSNGYREPPEPDGWAGGLRGLPPTQTKCKQPNCSFYGHPETNNFCSCCYREELR 828

Query: 296 EEEPRSTGEL 305
             E    GEL
Sbjct: 829 RREREPDGEL 838


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 11  EEGGNQQMHRKTASLNSPVSCKEKPDRVEEPPDYSLHWPEGLKGEE 56
           E   NQQ HR   S     S   +P   +EP   + H P GLKGE+
Sbjct: 234 ERPQNQQPHRAQRSPQQQPSRLHRPQN-QEPQSQAAHGPRGLKGEK 278


>gi|7662470 neuroligin 1 [Homo sapiens]
          Length = 823

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 25/118 (21%), Positives = 51/118 (43%), Gaps = 20/118 (16%)

Query: 148 LAITTNTSQKYIFVSLLSRDSVY--------DLLRRVC---------THLQPSSKKSLSV 190
           L++T       +F+++L+  ++Y        D+ RR           TH Q     SL +
Sbjct: 676 LSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQM 735

Query: 191 REFSGEPESLEVLIPEMKWRKVCPSSRSLSL---PDNIPCIPPSSVDSTDSFFPSRKP 245
           +    + E   +   E+  R  CP   +L++   PD++P + P+++    +  P  +P
Sbjct: 736 KHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQP 793


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 214 PSSRSLSLPD-NIPCIPPSSVDSTDSFFPSRK-PPMSEKSRAQVASENGGRW 263
           PSS++   P+ N   + PSSV+  DSFF  R   PM EK      SE   R+
Sbjct: 661 PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRY 712


>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
           interacting protein [Homo sapiens]
          Length = 1211

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 27/103 (26%)

Query: 182 PSSKKSLSVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIPCIPPSSVDSTDSFFP 241
           PS   +   R  SG     E L+P   +  +C  S  L+ P +    P +S+DS      
Sbjct: 584 PSPAVTTGPRTLSGVSWPSERLLPSPCYHPLC--SGGLASPSSSESHPYASLDS------ 635

Query: 242 SRKPPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPT 284
           SR P                    P PG GP CP   P+  PT
Sbjct: 636 SRAPS-------------------PQPGPGPICPDSPPSPDPT 659


>gi|7662354 MON1 homolog B [Homo sapiens]
          Length = 547

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 270 WGPACPKKMPNCSPTAKNAVYEEDELEEEPRS 301
           W PA P+  P CSP + +     D  +EE RS
Sbjct: 76  WSPAAPENSPTCSPESSSGGQGGDPSDEEWRS 107


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 10/97 (10%)

Query: 145 PNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSLSVREFSGEPESLEVLI 204
           P+   +T    Q+Y +     R  +  L +R   HL P  KK   V + + EP   EV +
Sbjct: 283 PDPSTMTPQEQQQYWY-----RQHLLSLQQRTKVHL-PGHKKGPVVAKDTPEPVKEEVTV 336

Query: 205 PEMKWRKVCPSSRSLSLP----DNIPCIPPSSVDSTD 237
           P        PSS    LP    +  P +PP    S D
Sbjct: 337 PATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSED 373


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,394,675
Number of Sequences: 37866
Number of extensions: 752866
Number of successful extensions: 2522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 2463
Number of HSP's gapped (non-prelim): 93
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.