BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|6005772 G protein-coupled receptor 176 [Homo sapiens] (515 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|6005772 G protein-coupled receptor 176 [Homo sapiens] 1023 0.0 gi|222080095 orexin receptor 1 [Homo sapiens] 102 6e-22 gi|222080109 orexin receptor 2 [Homo sapiens] 102 1e-21 gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 99 1e-20 gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 98 2e-20 gi|157426873 tachykinin receptor 2 [Homo sapiens] 89 1e-17 gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 87 5e-17 gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 87 5e-17 gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 84 4e-16 gi|15150803 opsin 4 isoform 1 [Homo sapiens] 83 7e-16 gi|4557865 somatostatin receptor 5 [Homo sapiens] 82 1e-15 gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 82 1e-15 gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 81 2e-15 gi|4503905 galanin receptor 2 [Homo sapiens] 81 2e-15 gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 81 2e-15 gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom... 81 3e-15 gi|4557861 somatostatin receptor 3 [Homo sapiens] 81 3e-15 gi|5453666 G protein-coupled receptor 19 [Homo sapiens] 80 4e-15 gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 79 8e-15 gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 79 8e-15 gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 79 8e-15 gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 79 8e-15 gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 79 8e-15 gi|4557857 somatostatin receptor 1 [Homo sapiens] 79 1e-14 gi|4501951 adenosine A2b receptor [Homo sapiens] 78 2e-14 gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 78 2e-14 gi|4502455 bombesin-like receptor 3 [Homo sapiens] 78 2e-14 gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 77 3e-14 gi|71999143 opsin 4 isoform 2 [Homo sapiens] 75 1e-13 gi|46391085 G protein-coupled receptor for asthma susceptibility... 75 1e-13 >gi|6005772 G protein-coupled receptor 176 [Homo sapiens] Length = 515 Score = 1023 bits (2646), Expect = 0.0 Identities = 515/515 (100%), Positives = 515/515 (100%) Query: 1 MGHNGSWISPNASEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNF 60 MGHNGSWISPNASEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNF Sbjct: 1 MGHNGSWISPNASEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNF 60 Query: 61 MVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVV 120 MVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVV Sbjct: 61 MVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVV 120 Query: 121 KFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAV 180 KFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAV Sbjct: 121 KFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAV 180 Query: 181 TNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKKV 240 TNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKKV Sbjct: 181 TNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKKV 240 Query: 241 IIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDTSVF 300 IIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDTSVF Sbjct: 241 IIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDTSVF 300 Query: 301 LLLTAVWLPKVSLLANPVLFLTVNKSVRKCLIGTLVQLHHRYSRRNVVSTGSGMAEASLE 360 LLLTAVWLPKVSLLANPVLFLTVNKSVRKCLIGTLVQLHHRYSRRNVVSTGSGMAEASLE Sbjct: 301 LLLTAVWLPKVSLLANPVLFLTVNKSVRKCLIGTLVQLHHRYSRRNVVSTGSGMAEASLE 360 Query: 361 PSIRSGSQLLEMFHIGQQQIFKPTEDEEESEAKYIGSADFQAKEIFSTCLEGEQGPQFAP 420 PSIRSGSQLLEMFHIGQQQIFKPTEDEEESEAKYIGSADFQAKEIFSTCLEGEQGPQFAP Sbjct: 361 PSIRSGSQLLEMFHIGQQQIFKPTEDEEESEAKYIGSADFQAKEIFSTCLEGEQGPQFAP 420 Query: 421 SAPPLSTVDSVSQVAPAAPVEPETFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLG 480 SAPPLSTVDSVSQVAPAAPVEPETFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLG Sbjct: 421 SAPPLSTVDSVSQVAPAAPVEPETFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLG 480 Query: 481 NTPEELIQTKVPKVGRVERKMSRNNKVSIFPKVDS 515 NTPEELIQTKVPKVGRVERKMSRNNKVSIFPKVDS Sbjct: 481 NTPEELIQTKVPKVGRVERKMSRNNKVSIFPKVDS 515 >gi|222080095 orexin receptor 1 [Homo sapiens] Length = 425 Score = 102 bits (255), Expect = 6e-22 Identities = 78/317 (24%), Positives = 140/317 (44%), Gaps = 39/317 (12%) Query: 40 YRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDI 99 Y V +F+ +L+GN +V + R ++VTN FI NL+ + + + +C+P + Sbjct: 45 YEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASL 104 Query: 100 ILSTSPHCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKS 159 ++ + W++ CKV+ +L V SV +L+ IALDR+Y++ +PL K + ++ Sbjct: 105 LVDITES---WLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRA 161 Query: 160 RELVMYIWAHAVVASVPVFAVTNVADIYAT--------STCTEVWSNSLGHLVYVLVYNI 211 R ++ IWA ++ VP AV + + S C E W++ L +Y + I Sbjct: 162 RGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFI 221 Query: 212 TTVIVPVVVVFLFLILIRRALSASQKKKVIIAALRT--------------------PQNT 251 T + P+ ++ + I R L Q A +R P+ Sbjct: 222 VTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRAR 281 Query: 252 ISIPYASQREAELHATLLSMV--MVFILCSVPYATLVVYQTVLNV-----PDTSVFLLLT 304 + Q A + MV +VF LC +P + L V + V + +V+ T Sbjct: 282 AFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFT 341 Query: 305 -AVWLPKVSLLANPVLF 320 + WL + ANP+++ Sbjct: 342 FSHWLVYANSAANPIIY 358 >gi|222080109 orexin receptor 2 [Homo sapiens] Length = 444 Score = 102 bits (253), Expect = 1e-21 Identities = 79/357 (22%), Positives = 159/357 (44%), Gaps = 49/357 (13%) Query: 49 VVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCC 108 +++F+ +L+GN +V + + ++VTN FI NL+ + + ++ C+P +++ + Sbjct: 62 IIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET-- 119 Query: 109 WWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWA 168 W + CKV+ +L V SV++L+ IALDR+Y++ +PL K + ++R ++ IW Sbjct: 120 -WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWI 178 Query: 169 HAVVASVPVFAVTNVADIY--------ATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVV 220 + + +P V + ++ + C E W + +Y + + + T + P+ + Sbjct: 179 VSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCL 238 Query: 221 VFLFLILIRRAL---------SASQKKKVIIAALRTPQ----------NTISIPYASQRE 261 + L + I R L S Q+K + + P+ + ++ R Sbjct: 239 MVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRA 298 Query: 262 AELHATLLSMV-MVFILCSVPYATLVVYQTVLNV------PDTSVFLLLTAVWLPKVSLL 314 A +L +V +VF +C +P + L V + V + +T + WL + Sbjct: 299 RRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSA 358 Query: 315 ANPVLFLTVNKSVRK--------CLIGTLVQLHHRYSRRNVVSTGSGMAEASLEPSI 363 ANP+++ ++ R+ C +G +HHR R S + SL I Sbjct: 359 ANPIIYNFLSGKFREEFKAAFSCCCLG----VHHRQEDRLTRGRTSTESRKSLTTQI 411 >gi|4758474 G protein-coupled receptor 10 [Homo sapiens] Length = 370 Score = 98.6 bits (244), Expect = 1e-20 Identities = 86/339 (25%), Positives = 149/339 (43%), Gaps = 27/339 (7%) Query: 11 NASEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTV----QVVIFIGSLLGNFMVLWST 66 N S +A AG + A+ F QL Q + VV+ +G L+GN +++ Sbjct: 27 NQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVG-LVGNCLLVLVI 85 Query: 67 CRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVKFLHKV 126 R +VTN I NLA S + CVP + + P W++ C +V FL V Sbjct: 86 ARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPR--GWVFGGGLCHLVFFLQPV 143 Query: 127 FCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAVTNVADI 186 V++ + IA+DRY +++PL R+IS S V+ IWA + V ++P T ++ Sbjct: 144 TVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVEL 203 Query: 187 --YATSTCTEVW-SNSLGHLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKKVIIA 243 + C E W S +Y + T ++P++V+ L + + S + +V+ Sbjct: 204 KPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRV----SVKLRNRVVPG 259 Query: 244 ALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDTSV---- 299 + Q + R L+ +V+VF +C +P L V+ + ++ ++ Sbjct: 260 CVTQSQ----ADWDRARRRRTFCLLVVVVVVFAVCWLP---LHVFNLLRDLDPHAIDPYA 312 Query: 300 --FLLLTAVWLPKVSLLANPVLFLTVNKSVRKCLIGTLV 336 + L WL S NP ++ ++ S R+ L LV Sbjct: 313 FGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLV 351 >gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] Length = 529 Score = 97.8 bits (242), Expect = 2e-20 Identities = 76/316 (24%), Positives = 146/316 (46%), Gaps = 32/316 (10%) Query: 42 QFTTTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIIL 101 QF + + IF+ LGN +++ + + + +++N+F+ +L S S++ +PF + Sbjct: 30 QFIAIIVITIFV--CLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTS 87 Query: 102 STSPHCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPL--ERKISDAKS 159 S WI+ +++C L+ + S ++L+ IA+DRYY+VLYP+ KI+ ++ Sbjct: 88 SIRRE---WIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRA 144 Query: 160 RELVMYIWAHAVVASV-PVFAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPV 218 ++YIW H+++ + P+F ++V C W G Y + I + P Sbjct: 145 VMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPG---YTAFWQIWCALFPF 201 Query: 219 VVVFLFLILIRRALSASQKK----KVIIA---ALRTPQNTISIPYASQ------------ 259 +V+ + I R +K V+I A RT + S +S Sbjct: 202 LVMLVCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVY 261 Query: 260 --REAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANP 317 + + T+L ++ F++ PY ++ + + S L A WL S + +P Sbjct: 262 SANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHP 321 Query: 318 VLFLTVNKSVRKCLIG 333 +++ NK+VRK L+G Sbjct: 322 LIYGLWNKTVRKELLG 337 >gi|157426873 tachykinin receptor 2 [Homo sapiens] Length = 398 Score = 88.6 bits (218), Expect = 1e-17 Identities = 72/327 (22%), Positives = 138/327 (42%), Gaps = 30/327 (9%) Query: 13 SEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTVF 72 +E + +SG E+ N + + F T + + + ++ GN +V+W Sbjct: 8 TEANISSGPES---NTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRM 64 Query: 73 KSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVKFLHKVFCSVTI 132 ++VTN FI NLA + +C + F+ + ++ H W+ + FC V+I Sbjct: 65 RTVTNYFIVNLALADLCMAAFNAAFNFVYAS--HNIWY-FGRAFCYFQNLFPITAMFVSI 121 Query: 133 LSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAVTNVADIYATSTC 192 S AIA DRY ++++P + ++S ++ ++ IW A+ + P + V + C Sbjct: 122 YSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATKC 181 Query: 193 TEVWSNSLG-------HLVYV-LVYNITTVIVPVVVVFLFLILIRRALSASQKKKVIIAA 244 W G HLV + L+Y + ++ V + L L RRA+ Q + Sbjct: 182 VVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRH 241 Query: 245 LRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVV---YQTVLNVPDTSVFL 301 L+ + + T++ +V+ F +C +PY + +Q + + Sbjct: 242 LQAMKKFVK-------------TMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQV 288 Query: 302 LLTAVWLPKVSLLANPVLFLTVNKSVR 328 L WL S + NP+++ +N R Sbjct: 289 YLALFWLAMSSTMYNPIIYCCLNHRFR 315 >gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] Length = 397 Score = 86.7 bits (213), Expect = 5e-17 Identities = 70/287 (24%), Positives = 132/287 (45%), Gaps = 15/287 (5%) Query: 45 TTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTS 104 T V V+ + ++ GN +V + +++TN FI +LA + + L+ +PF I S Sbjct: 22 TVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLS 81 Query: 105 PHCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELV- 163 C W + +FC + L + C+ +IL+ I+LDRY +V+ PL + R + Sbjct: 82 ---CKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAIS 138 Query: 164 -MYIWAHAVVAS-VPVFAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVV 221 + IW ++ S + + N + + T + VY LV + T +P++++ Sbjct: 139 LVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIM 198 Query: 222 FLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVP 281 + I + ++ Q K++ + S A+ RE + TL +++ FI+C P Sbjct: 199 CITYYRIFK-VARDQAKRI--------NHISSWKAATIREHKATVTLAAVMGAFIICWFP 249 Query: 282 YATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVR 328 Y T VY+ + + L +WL + NP+L+ +N+ R Sbjct: 250 YFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFR 296 >gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] Length = 359 Score = 86.7 bits (213), Expect = 5e-17 Identities = 70/287 (24%), Positives = 132/287 (45%), Gaps = 15/287 (5%) Query: 45 TTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTS 104 T V V+ + ++ GN +V + +++TN FI +LA + + L+ +PF I S Sbjct: 22 TVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLS 81 Query: 105 PHCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELV- 163 C W + +FC + L + C+ +IL+ I+LDRY +V+ PL + R + Sbjct: 82 ---CKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAIS 138 Query: 164 -MYIWAHAVVAS-VPVFAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVV 221 + IW ++ S + + N + + T + VY LV + T +P++++ Sbjct: 139 LVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIM 198 Query: 222 FLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVP 281 + I + ++ Q K++ + S A+ RE + TL +++ FI+C P Sbjct: 199 CITYYRIFK-VARDQAKRI--------NHISSWKAATIREHKATVTLAAVMGAFIICWFP 249 Query: 282 YATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVR 328 Y T VY+ + + L +WL + NP+L+ +N+ R Sbjct: 250 YFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFR 296 >gi|62865887 G protein-coupled receptor 54 [Homo sapiens] Length = 398 Score = 83.6 bits (205), Expect = 4e-16 Identities = 67/294 (22%), Positives = 127/294 (43%), Gaps = 12/294 (4%) Query: 3 HNGSWISPNAS--EPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNF 60 H + PNAS P NASG G N S + + + L+GN Sbjct: 2 HTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNS 61 Query: 61 MVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVV 120 +V++ CR ++VTN +I NLA + + L CVPF +L P W+ CK V Sbjct: 62 LVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLP---GWVLGDFMCKFV 118 Query: 121 KFLHKVFCSVTILSFPAIALDRYYSVLYPLE--RKISDAKSRELVMYIWAHAVVASVPVF 178 ++ +V T + A+++DR+Y ++PL + + + + + IW + S PV Sbjct: 119 NYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVL 178 Query: 179 AVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVV-FLFLILIRRALSASQK 237 A+ ++ + C+E + + + L + ++P++ + ++R + + Sbjct: 179 ALHRLSP-GPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVR 237 Query: 238 KKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTV 291 +AL Q + A A++ + ++V++F C P +V Q + Sbjct: 238 PAPADSAL---QGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQAL 288 >gi|15150803 opsin 4 isoform 1 [Homo sapiens] Length = 478 Score = 82.8 bits (203), Expect = 7e-16 Identities = 66/309 (21%), Positives = 137/309 (44%), Gaps = 13/309 (4%) Query: 46 TVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSP 105 TV +++ + +LGN V+++ CR+ ++ N FI NLA S S P + TS Sbjct: 75 TVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAP---VFFTSS 131 Query: 106 HCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLER--KISDAKSRELV 163 W++ C+ F +F ++++ AIALDRY + PL S ++ ++ Sbjct: 132 LYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVL 191 Query: 164 MYIWAHAVVASVPVFA--VTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVV 221 + +W +A+ S+P F V + TS + S + Y ++ +P++++ Sbjct: 192 LGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLII 251 Query: 222 FLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVP 281 I I RA+ + + A + ++ Q E ++ +L ++++F+L P Sbjct: 252 IYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAP 311 Query: 282 YATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVRKCL------IGTL 335 Y+ + + + ++ + K S + NP+++ + R + +G L Sbjct: 312 YSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVL 371 Query: 336 VQLHHRYSR 344 + + R+SR Sbjct: 372 LGVSRRHSR 380 >gi|4557865 somatostatin receptor 5 [Homo sapiens] Length = 364 Score = 82.0 bits (201), Expect = 1e-15 Identities = 82/332 (24%), Positives = 149/332 (44%), Gaps = 37/332 (11%) Query: 6 SWISPNASEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNFMVLWS 65 SW NAS P ASG G NR+ +G A + +++ L GN +V++ Sbjct: 11 SW---NASSPGAASGG---GDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYV 64 Query: 66 TCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVKFLHK 125 R K+VTN +I NLA + + ++ +PF L+T +W + + C++V L Sbjct: 65 VLRFAKMKTVTNIYILNLAVADV-LYMLGLPF---LATQNAASFWPFGPVLCRLVMTLDG 120 Query: 126 VFCSVTILSFPAIALDRYYSVLYPLE----RKISDAKSRELVMYIWAHAVVASVPVFAVT 181 V ++ +++DRY +V++PL R+ AK W ++ S+P+ Sbjct: 121 VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAA--AWVLSLCMSLPLLV-- 176 Query: 182 NVADIYATSTCTEVWSNSLG--HLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKK 239 AD+ TC W +G V+++ + P++V+ L +LI + A+ Sbjct: 177 -FADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAA---G 232 Query: 240 VIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPD--T 297 V + +R + E ++ +L +V+VF C +P+ T+ + + +P Sbjct: 233 VRVGCVR-----------RRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPA 281 Query: 298 SVFLLLTAVWLPKVSLLANPVLFLTVNKSVRK 329 S L V L + ANPVL+ ++ + R+ Sbjct: 282 SAGLYFFVVILSYANSCANPVLYGFLSDNFRQ 313 >gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] Length = 407 Score = 82.0 bits (201), Expect = 1e-15 Identities = 69/284 (24%), Positives = 133/284 (46%), Gaps = 16/284 (5%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 VI + S++GN +V+W ++VTN F+ NLA + AS+ + + + H W Sbjct: 41 VIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAE--ASMAAFNTVVNFTYAVHNEW 98 Query: 110 WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAH 169 + Y + +CK F +I S A+A DRY ++++PL+ ++S ++ ++ IW Sbjct: 99 Y-YGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVL 157 Query: 170 AVVASVPVFAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIR 229 A++ + P + + + C W + +Y VY+I V V++ FL L++I Sbjct: 158 ALLLAFPQGYYSTTETMPSRVVCMIEWPEH-PNKIYEKVYHI---CVTVLIYFLPLLVIG 213 Query: 230 RALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMV--FILCSVPYATLVV 287 A + + + A P ++ S Y Q A+ + +V+V F +C +P+ + Sbjct: 214 YAYTV---VGITLWASEIPGDS-SDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFL 269 Query: 288 YQTV---LNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVR 328 + L + + L +WL S + NP+++ +N R Sbjct: 270 LPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFR 313 >gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] Length = 311 Score = 81.3 bits (199), Expect = 2e-15 Identities = 68/280 (24%), Positives = 132/280 (47%), Gaps = 16/280 (5%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 VI + S++GN +V+W ++VTN F+ NLA + AS+ + + + H W Sbjct: 41 VIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAE--ASMAAFNTVVNFTYAVHNEW 98 Query: 110 WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAH 169 + Y + +CK F +I S A+A DRY ++++PL+ ++S ++ ++ IW Sbjct: 99 Y-YGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVL 157 Query: 170 AVVASVPVFAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIR 229 A++ + P + + + C W + +Y VY+I V V++ FL L++I Sbjct: 158 ALLLAFPQGYYSTTETMPSRVVCMIEWPEH-PNKIYEKVYHI---CVTVLIYFLPLLVIG 213 Query: 230 RALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMV--FILCSVPYATLVV 287 A + + + A P ++ S Y Q A+ + +V+V F +C +P+ + Sbjct: 214 YAYTV---VGITLWASEIPGDS-SDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFL 269 Query: 288 YQTV---LNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVN 324 + L + + L +WL S + NP+++ +N Sbjct: 270 LPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLN 309 >gi|4503905 galanin receptor 2 [Homo sapiens] Length = 387 Score = 81.3 bits (199), Expect = 2e-15 Identities = 76/317 (23%), Positives = 132/317 (41%), Gaps = 21/317 (6%) Query: 17 NASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVT 76 N SG AG N S G G + +IF+ +GN +VL R S T Sbjct: 2 NVSGCPGAG-NASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTT 60 Query: 77 NRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVKFLHKVFCSVTILSFP 136 N FI NL + +C L CVPF + T W++ L CK V FL + + + Sbjct: 61 NLFILNLGVADLCFILCCVPFQATIYTLD---GWVFGSLLCKAVHFLIFLTMHASSFTLA 117 Query: 137 AIALDRYYSVLYPLERKISDAKSREL--VMYIWAHAVVASVPVFAVTNVADIYATSTCTE 194 A++LDRY ++ YPL + L + IW +++ S P + + + + C Sbjct: 118 AVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHP 177 Query: 195 VWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKKVIIAALRTPQNTISI 254 WS + + + + + ++PV+V+ L R L R + Sbjct: 178 AWSAPRRRAMDICTF-VFSYLLPVLVLGLTYARTLRYL------------WRAVDPVAAG 224 Query: 255 PYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDT--SVFLLLTAVWLPKVS 312 A + + ++ +L + +F LC +P+ L++ P T + L + + + + Sbjct: 225 SGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYAN 284 Query: 313 LLANPVLFLTVNKSVRK 329 NP+++ V+K RK Sbjct: 285 SCVNPIVYALVSKHFRK 301 >gi|157738685 G protein-coupled receptor 103 [Homo sapiens] Length = 431 Score = 81.3 bits (199), Expect = 2e-15 Identities = 62/300 (20%), Positives = 138/300 (46%), Gaps = 18/300 (6%) Query: 49 VVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCC 108 V+IF +L GN +V + R+ ++VTN FI +LA S + + C+P ++ + S + Sbjct: 53 VLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDN-- 110 Query: 109 WWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVM--YI 166 W+ CK+V F+ IL+ IA++R+ +++P + K R M + Sbjct: 111 -WLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVV 169 Query: 167 WAHAVVASVPVFAVTNVADIY------ATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVV 220 W AV+ P++ V + Y C E W++ + +Y + ++P++V Sbjct: 170 WLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMV 229 Query: 221 VFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSV 280 + + I L KK+V ++ + + ++++ ++++V +F +C Sbjct: 230 MLILYSKIGYELWI--KKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWA 287 Query: 281 PYATLVVYQTVLN----VPDTSVFLLLTAVWLPKVS-LLANPVLFLTVNKSVRKCLIGTL 335 P+ + + N D ++ ++ V + S + NP+++ +N++ +K ++ + Sbjct: 288 PFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAV 347 >gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo sapiens] Length = 366 Score = 80.9 bits (198), Expect = 3e-15 Identities = 78/339 (23%), Positives = 149/339 (43%), Gaps = 37/339 (10%) Query: 45 TTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTS 104 T V +F+ + GN + + R ++ TN ++ ++A S + L C+P D++ Sbjct: 47 TATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFL-CMPLDLVR--- 102 Query: 105 PHCCW----WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSR 160 W W + L CK+ +F+ + T+L+ A++++RY+++ +PL K+ K R Sbjct: 103 ---LWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGR 159 Query: 161 -ELVMY-IWAHAVVASVPVFAVTNV-----ADIYATSTCTEVWSNSLGHLVYVLVY-NIT 212 +LV++ IWA A ++ P+F + V D + T+ C L+ V+V+ + Sbjct: 160 VKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSI 219 Query: 213 TVIVPVVVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMV 272 +PV + + LI R L ++ ++ A QN + L +V Sbjct: 220 FFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQN----------HKQTVKMLAVVV 269 Query: 273 MVFILCSVPY------ATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKS 326 FILC +P+ + L + S + L + L +S NP+L+ ++K Sbjct: 270 FAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKK 329 Query: 327 VRKCLIGTLVQLHHRYSRRNVVSTGSGMAEASLEPSIRS 365 R + L +S+R + + + A E SI + Sbjct: 330 YRVAVFRLLG--FEPFSQRKLSTLKDESSRAWTESSINT 366 >gi|4557861 somatostatin receptor 3 [Homo sapiens] Length = 418 Score = 80.9 bits (198), Expect = 3e-15 Identities = 80/323 (24%), Positives = 140/323 (43%), Gaps = 37/323 (11%) Query: 13 SEPHNASGA---EAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNFMVLWSTCRT 69 SEP NAS A +A N SA + V +V+ + LLGN +V++ R Sbjct: 13 SEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRH 72 Query: 70 TVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVKFLHKVFCS 129 T SVTN +I NLA + ++ +PF L+ +W + L C++V + + Sbjct: 73 TASPSVTNVYILNLALADE-LFMLGLPF---LAAQNALSYWPFGSLMCRLVMAVDGINQF 128 Query: 130 VTILSFPAIALDRYYSVLYPLE--RKISDAKSRELVMYIWAHAVVASVPVFAVTNVADIY 187 +I +++DRY +V++P R + +R + +W + V +PV + V Sbjct: 129 TSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVP--R 186 Query: 188 ATSTCTEVWSN-----SLGHLVYVLVYNITTVIVPVVVVFLFLILIRRALSASQKKKVII 242 STC W G ++Y P++V+ L +L I+ Sbjct: 187 GMSTCHMQWPEPAAAWRAGFIIYTAALGF---FGPLLVICLCYLL-------------IV 230 Query: 243 AALRTPQNTISIPYASQR---EAELHATLLSMVMVFILCSVPYATLVVYQTVLNVPDTSV 299 +R+ + P +R E + ++++V +F+LC +P+ L + V +P+ Sbjct: 231 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 290 Query: 300 F--LLLTAVWLPKVSLLANPVLF 320 F L V LP + ANP+L+ Sbjct: 291 FFGLYFLVVALPYANSCANPILY 313 >gi|5453666 G protein-coupled receptor 19 [Homo sapiens] Length = 415 Score = 80.1 bits (196), Expect = 4e-15 Identities = 68/314 (21%), Positives = 136/314 (43%), Gaps = 26/314 (8%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 ++++ S+ GN +V R+ +S TN F+ ++AC+ + S+ PF ++ T+ Sbjct: 74 ILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGR--- 130 Query: 110 WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAH 169 W CKVV++ + V I +I +DR+Y+++YPL K+S K+++++ W Sbjct: 131 WTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWI- 189 Query: 170 AVVASVPVFAVTNVADIYAT---STCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLI 226 VT V Y + S C +S Y +++ + ++P V++ LF Sbjct: 190 -----FDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFY- 243 Query: 227 LIRRALSASQKKKVIIAALRTPQNTI--SIPYASQREAELHATLLSMVMVFILCSVPYAT 284 QK I + T T+ ++ + + + L + ++F+L +P+ Sbjct: 244 ---------QKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHV 294 Query: 285 LVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVRKCLIGTLVQLHHRYSR 344 ++ S + W+ S + P L+ N + R+ + T + R Sbjct: 295 AQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYR 354 Query: 345 RN--VVSTGSGMAE 356 N ++T S MA+ Sbjct: 355 SNAYTITTSSRMAK 368 >gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] Length = 420 Score = 79.3 bits (194), Expect = 8e-15 Identities = 63/303 (20%), Positives = 130/303 (42%), Gaps = 37/303 (12%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 +IF ++GN +V + R +VTN FI NLA S + + C+P ++ + Sbjct: 54 LIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNI---IAG 110 Query: 110 WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAH 169 W + CK+ + + + ++ + AIA+DR+ V+YP + K++ + ++M IW Sbjct: 111 WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVL 170 Query: 170 AVVASVPVFAVTNVAD-------------IYATSTCTEVWSNSLGHLVYVLVYNITTVIV 216 A+ P + +V + C E W N +Y V + Sbjct: 171 AITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLA 230 Query: 217 PVVVVFLF-----LILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSM 271 P+ ++ + + L R A+ + +K N S+++ ++ LL + Sbjct: 231 PLSLIVIMYGRIGISLFRAAVPHTGRK-----------NQEQWHVVSRKKQKIIKMLLIV 279 Query: 272 VMVFILCSVPYATLVVYQTVLNVPDT-----SVFLLLTAVWLPKVSLLANPVLFLTVNKS 326 ++FIL +P TL++ ++ ++++ A WL + NP+++ N++ Sbjct: 280 ALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNEN 339 Query: 327 VRK 329 R+ Sbjct: 340 FRR 342 >gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] Length = 522 Score = 79.3 bits (194), Expect = 8e-15 Identities = 63/303 (20%), Positives = 130/303 (42%), Gaps = 37/303 (12%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 +IF ++GN +V + R +VTN FI NLA S + + C+P ++ + Sbjct: 156 LIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNI---IAG 212 Query: 110 WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAH 169 W + CK+ + + + ++ + AIA+DR+ V+YP + K++ + ++M IW Sbjct: 213 WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVL 272 Query: 170 AVVASVPVFAVTNVAD-------------IYATSTCTEVWSNSLGHLVYVLVYNITTVIV 216 A+ P + +V + C E W N +Y V + Sbjct: 273 AITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLA 332 Query: 217 PVVVVFLF-----LILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSM 271 P+ ++ + + L R A+ + +K N S+++ ++ LL + Sbjct: 333 PLSLIVIMYGRIGISLFRAAVPHTGRK-----------NQEQWHVVSRKKQKIIKMLLIV 381 Query: 272 VMVFILCSVPYATLVVYQTVLNVPDT-----SVFLLLTAVWLPKVSLLANPVLFLTVNKS 326 ++FIL +P TL++ ++ ++++ A WL + NP+++ N++ Sbjct: 382 ALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNEN 441 Query: 327 VRK 329 R+ Sbjct: 442 FRR 444 >gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] Length = 423 Score = 79.3 bits (194), Expect = 8e-15 Identities = 63/303 (20%), Positives = 130/303 (42%), Gaps = 37/303 (12%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 +IF ++GN +V + R +VTN FI NLA S + + C+P ++ + Sbjct: 57 LIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNI---IAG 113 Query: 110 WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAH 169 W + CK+ + + + ++ + AIA+DR+ V+YP + K++ + ++M IW Sbjct: 114 WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVL 173 Query: 170 AVVASVPVFAVTNVAD-------------IYATSTCTEVWSNSLGHLVYVLVYNITTVIV 216 A+ P + +V + C E W N +Y V + Sbjct: 174 AITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLA 233 Query: 217 PVVVVFLF-----LILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSM 271 P+ ++ + + L R A+ + +K N S+++ ++ LL + Sbjct: 234 PLSLIVIMYGRIGISLFRAAVPHTGRK-----------NQEQWHVVSRKKQKIIKMLLIV 282 Query: 272 VMVFILCSVPYATLVVYQTVLNVPDT-----SVFLLLTAVWLPKVSLLANPVLFLTVNKS 326 ++FIL +P TL++ ++ ++++ A WL + NP+++ N++ Sbjct: 283 ALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNEN 342 Query: 327 VRK 329 R+ Sbjct: 343 FRR 345 >gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] Length = 384 Score = 79.3 bits (194), Expect = 8e-15 Identities = 67/313 (21%), Positives = 140/313 (44%), Gaps = 34/313 (10%) Query: 49 VVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCC 108 V+I IG L+GN ++ C ++V N FI +LA + + C P D + Sbjct: 49 VIILIG-LIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADR-- 105 Query: 109 WWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELV--MYI 166 W++ + CK++ F+ V++ + A++ DRY +++ P++ + S A + + +I Sbjct: 106 -WLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFI 164 Query: 167 WAHAVVASVPVFAVTNVADIYATST------CTEV-WSNSLGHLVYVLVYNITTVIVPVV 219 W +++ ++P +++ + ST C SN L ++ + + ++P+ Sbjct: 165 WIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLS 224 Query: 220 VVFLFLILIRRALSASQKKKVIIAALRTP-QNTISIPYASQREAELHATLLSMVMVFILC 278 ++ ++ I K +I +A P + I + + L T+L V +F C Sbjct: 225 IISVYYYFI--------AKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFC 276 Query: 279 SVPYATLVVYQTV-LNVPDTSVFLLLTAV---WLPKVSLLANPVLFLTVNKSVRK----- 329 +P + +Y++ + DTS+ +T++ L + NP ++KS RK Sbjct: 277 WLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQ 336 Query: 330 ---CLIGTLVQLH 339 C G +++ H Sbjct: 337 LLCCQPGLIIRSH 349 >gi|239757761 PREDICTED: similar to gastrin-releasing peptide receptor [Homo sapiens] Length = 368 Score = 79.3 bits (194), Expect = 8e-15 Identities = 67/313 (21%), Positives = 140/313 (44%), Gaps = 34/313 (10%) Query: 49 VVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCC 108 V+I IG L+GN ++ C ++V N FI +LA + + C P D + Sbjct: 33 VIILIG-LIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADR-- 89 Query: 109 WWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELV--MYI 166 W++ + CK++ F+ V++ + A++ DRY +++ P++ + S A + + +I Sbjct: 90 -WLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFI 148 Query: 167 WAHAVVASVPVFAVTNVADIYATST------CTEV-WSNSLGHLVYVLVYNITTVIVPVV 219 W +++ ++P +++ + ST C SN L ++ + + ++P+ Sbjct: 149 WIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLS 208 Query: 220 VVFLFLILIRRALSASQKKKVIIAALRTP-QNTISIPYASQREAELHATLLSMVMVFILC 278 ++ ++ I K +I +A P + I + + L T+L V +F C Sbjct: 209 IISVYYYFI--------AKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFC 260 Query: 279 SVPYATLVVYQTV-LNVPDTSVFLLLTAV---WLPKVSLLANPVLFLTVNKSVRK----- 329 +P + +Y++ + DTS+ +T++ L + NP ++KS RK Sbjct: 261 WLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQ 320 Query: 330 ---CLIGTLVQLH 339 C G +++ H Sbjct: 321 LLCCQPGLIIRSH 333 >gi|4557857 somatostatin receptor 1 [Homo sapiens] Length = 391 Score = 78.6 bits (192), Expect = 1e-14 Identities = 81/325 (24%), Positives = 141/325 (43%), Gaps = 29/325 (8%) Query: 2 GHNGSWISPNASEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVVIFIGSLLGNFM 61 G G P A A G E G N S G E Q + + V+ + L GN M Sbjct: 22 GEGGGSRGPGAGA---ADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSM 78 Query: 62 VLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVK 121 V++ R K+ TN +I NLA + ++ VPF L TS W + L C++V Sbjct: 79 VIYVILRYAKMKTATNIYILNLAIADELL-MLSVPF---LVTSTLLRHWPFGALLCRLVL 134 Query: 122 FLHKVFCSVTILSFPAIALDRYYSVLYPLE----RKISDAKSRELVMYIWAHAVVASVPV 177 + V +I +++DRY +V++P++ R+ + AK L +++ + V+ + V Sbjct: 135 SVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVV 194 Query: 178 FAVTNVADIYATSTCTEVWSNSLGHLV--YVLVYNITTVIVPVVVVFLFLILIRRALSAS 235 F+ T A+ T C + + +VL + ++PV + L +L Sbjct: 195 FSRT-AANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVL-------- 245 Query: 236 QKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPYATLVVYQTVLNVP 295 IIA +R + E ++ ++ +VMVF++C +P+ + + Sbjct: 246 -----IIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD 300 Query: 296 DTSVFLLLTAVWLPKVSLLANPVLF 320 D +V L +V L + ANP+L+ Sbjct: 301 DATVSQL--SVILGYANSCANPILY 323 >gi|4501951 adenosine A2b receptor [Homo sapiens] Length = 332 Score = 77.8 bits (190), Expect = 2e-14 Identities = 84/335 (25%), Positives = 144/335 (42%), Gaps = 31/335 (9%) Query: 47 VQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPH 106 +++VI S+ GN +V + ++ TN F+ +LA + + L +PF I +S Sbjct: 13 LELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLG-- 70 Query: 107 CCWWIYTMLF--CKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERK--ISDAKSREL 162 C Y LF C V+ V +I S A+A+DRY ++ PL K ++ ++R + Sbjct: 71 FCTDFYGCLFLACFVL-----VLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGV 125 Query: 163 VMYIWAHAVVASVPVFAVTNVADIYATSTCTEVWSNSLGH---LVYVLVYNITTVIVPVV 219 + +W A + F N D AT+ CTE W + LV L N+ + V Sbjct: 126 IAVLWVLAFGIGLTPFLGWNSKD-SATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVY 184 Query: 220 VVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYAS---QREAELHATLLSMVMVFI 276 F +L + K+ + A R Q T + ++ QRE +L +V +F Sbjct: 185 FNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFA 244 Query: 277 LCSVPY-----ATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVRKCL 331 LC +P TL N P ++ + A+ L + + NP+++ N+ R Sbjct: 245 LCWLPVHAVNCVTLFQPAQGKNKPKWAMNM---AILLSHANSVVNPIVYAYRNRDFRY-- 299 Query: 332 IGTLVQLHHRYSRRNVVSTGSGMAEASLEPSIRSG 366 T ++ RY SG +A ++P++ G Sbjct: 300 --TFHKIISRYLLCQ-ADVKSGNGQAGVQPALGVG 331 >gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] Length = 381 Score = 77.8 bits (190), Expect = 2e-14 Identities = 65/291 (22%), Positives = 132/291 (45%), Gaps = 21/291 (7%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 +I +G ++GN +V+ + ++VTN FI NLA + + + +C+PF + + Sbjct: 60 IILLG-VIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE--- 115 Query: 110 WIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAH 169 W + C +V + + V+ ++ IALDR+ ++Y LE KIS S ++ W Sbjct: 116 WKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGI 175 Query: 170 AVVASVPV-----FAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLF 224 + + + P+ +++ + + CTE W +Y VY+++++++ V+ Sbjct: 176 SALLASPLAIFREYSLIEIIPDFEIVACTEKWPGE-EKSIYGTVYSLSSLLILYVLPLGI 234 Query: 225 LILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVP-YA 283 + + + K V A + QR + L+ +V+VF + +P +A Sbjct: 235 ISFSYTRIWSKLKNHVSPGAAN--------DHYHQRRQKTTKMLVCVVVVFAVSWLPLHA 286 Query: 284 TLVVYQTVLNVPDTSVFLLLTAVW--LPKVSLLANPVLFLTVNKSVRKCLI 332 + V D + L+ V+ + S ANP+L+ +N + RK + Sbjct: 287 FQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFL 337 >gi|4502455 bombesin-like receptor 3 [Homo sapiens] Length = 399 Score = 77.8 bits (190), Expect = 2e-14 Identities = 67/262 (25%), Positives = 121/262 (46%), Gaps = 36/262 (13%) Query: 46 TVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSP 105 T V+I +G +LGN +++ +T ++V N FI +LA + L CVP D +T Sbjct: 53 TYAVIISVG-ILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVD---ATHY 108 Query: 106 HCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVM- 164 W++ + CKV+ F+ V++ + ++ DRY +V+ PLER+ S+A + V Sbjct: 109 LAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKA 168 Query: 165 -YIWAHAVVASVPVFAVTNVADI------YATSTCTEV-WSNSLGHLVYVLVYNITTVIV 216 +W +++ ++P +NV +CT S L ++ L+ + I+ Sbjct: 169 GCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYII 228 Query: 217 PVVVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREA--------ELHATL 268 P+ ++ ++ LI R L S T++IP Q A + T+ Sbjct: 229 PLSIISVYYSLIARTLYKS---------------TLNIPTEEQSHARKQIESRKRIARTV 273 Query: 269 LSMVMVFILCSVPYATLVVYQT 290 L +V +F LC +P L +Y + Sbjct: 274 LVLVALFALCWLPNHLLYLYHS 295 >gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] Length = 430 Score = 77.4 bits (189), Expect = 3e-14 Identities = 76/344 (22%), Positives = 140/344 (40%), Gaps = 38/344 (11%) Query: 10 PNASEPHNASGAEAAGVNRSALGEFGEAQLYRQFTTTVQVV-------IFIGSLLGNFMV 62 PN+S P + +G + L Y Q T+ V + IF+ ++GN +V Sbjct: 9 PNSSWPLSQNGTNTEATPATNL----TFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLV 64 Query: 63 LWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCWWIYTMLFCKVVKF 122 + + +VTN FI NLA S + + C+P ++ + W + CK+ Sbjct: 65 CFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNL---ITGWPFDNATCKMSGL 121 Query: 123 LHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPV----- 177 + + S ++ + AIA++R+ +++P K++ K+ + IWA A++ P Sbjct: 122 VQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLT 181 Query: 178 -------FAVTNVADIYATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVVFLFLILIRR 230 F V Y +C E W VY V + P+ ++ + I R Sbjct: 182 VTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIAR 241 Query: 231 ALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMVFILCSVPY--ATLVVY 288 L + + P AS+R A + L+ + + F L +P L++ Sbjct: 242 KLCQA-------PGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLID 294 Query: 289 QTVLNVPD---TSVFLLLTAVWLPKVSLLANPVLFLTVNKSVRK 329 L+ P +V+ A WL + ANP+++ N++ R+ Sbjct: 295 YGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRR 338 >gi|71999143 opsin 4 isoform 2 [Homo sapiens] Length = 489 Score = 75.5 bits (184), Expect = 1e-13 Identities = 66/320 (20%), Positives = 137/320 (42%), Gaps = 24/320 (7%) Query: 46 TVQVVIFIGSLLGNFMVLWSTCRTTV-----------FKSVTNRFIKNLACSGICASLVC 94 TV +++ + +LGN V+++ CR + ++ N FI NLA S S Sbjct: 75 TVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQ 134 Query: 95 VPFDIILSTSPHCCWWIYTMLFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLER-- 152 P + TS W++ C+ F +F ++++ AIALDRY + PL Sbjct: 135 AP---VFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFG 191 Query: 153 KISDAKSRELVMYIWAHAVVASVPVFA--VTNVADIYATSTCTEVWSNSLGHLVYVLVYN 210 S ++ +++ +W +A+ S+P F V + TS + S + Y ++ Sbjct: 192 VASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLC 251 Query: 211 ITTVIVPVVVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLS 270 +P++++ I I RA+ + + A + ++ Q E ++ +L Sbjct: 252 CFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLL 311 Query: 271 MVMVFILCSVPYATLVVYQTVLNVPDTSVFLLLTAVWLPKVSLLANPVLFLTVNKSVRKC 330 ++++F+L PY+ + + + ++ + K S + NP+++ + R Sbjct: 312 VILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVA 371 Query: 331 L------IGTLVQLHHRYSR 344 + +G L+ + R+SR Sbjct: 372 IAQHLPCLGVLLGVSRRHSR 391 >gi|46391085 G protein-coupled receptor for asthma susceptibility isoform B [Homo sapiens] Length = 377 Score = 75.5 bits (184), Expect = 1e-13 Identities = 66/302 (21%), Positives = 137/302 (45%), Gaps = 23/302 (7%) Query: 50 VIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW 109 V+F+ +++GN +VL+ST R KS F+ LA + LV + DI Sbjct: 58 VLFVFTIVGNSVVLFSTWRRKK-KSRMTFFVTQLAITDSFTGLVNILTDIN--------- 107 Query: 110 WIYTM------LFCKVVKFLHKVFCSVTILSFPAIALDRYYSVLYPLERKISDAKSRELV 163 W +T L C+VV++L V + ++++DRY++++YP++ + ++R L+ Sbjct: 108 WRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLI 167 Query: 164 MYIWAHAVVASVPVFAVTNVADI-YATSTCTEVWSNSLGHLVYVLVYNITTVIVPVVVV- 221 + W+ + + S+P + + C +W + Y+ + +P+ ++ Sbjct: 168 VIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIIS 227 Query: 222 FLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVMV--FILCS 279 ++ I+IR S+ + +I+ + S +A++ A S++++ FI C Sbjct: 228 IMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCW 287 Query: 280 VPYATLVVYQTVLNVPDTSVFLLLTAVW--LPKVSLLANPVLFLTVNKSVR-KCLIGTLV 336 PY + +PDT + + LP ++ NP+++ + S+ C + L Sbjct: 288 SPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCRVIRLR 347 Query: 337 QL 338 QL Sbjct: 348 QL 349 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.134 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,463,407 Number of Sequences: 37866 Number of extensions: 789550 Number of successful extensions: 3477 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 147 Number of HSP's successfully gapped in prelim test: 292 Number of HSP's that attempted gapping in prelim test: 2910 Number of HSP's gapped (non-prelim): 532 length of query: 515 length of database: 18,247,518 effective HSP length: 107 effective length of query: 408 effective length of database: 14,195,856 effective search space: 5791909248 effective search space used: 5791909248 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.