Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 59710104
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|59710104 plexin A3 [Homo sapiens]
(1871 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|59710104 plexin A3 [Homo sapiens] 3787 0.0
gi|49355818 plexin A1 [Homo sapiens] 2550 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 2306 0.0
gi|113722116 plexin A2 [Homo sapiens] 2268 0.0
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 913 0.0
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 913 0.0
gi|149363636 plexin B2 [Homo sapiens] 893 0.0
gi|157694524 plexin D1 [Homo sapiens] 860 0.0
gi|194272180 plexin B1 [Homo sapiens] 751 0.0
gi|40254442 plexin B1 [Homo sapiens] 751 0.0
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 462 e-129
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 461 e-129
gi|5032223 plexin C1 [Homo sapiens] 404 e-112
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 129 2e-29
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 129 2e-29
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 117 8e-26
gi|21361914 semaphorin B [Homo sapiens] 75 6e-13
gi|157388902 semaphorin 4C [Homo sapiens] 69 3e-11
gi|126116589 fibrocystin L [Homo sapiens] 69 3e-11
gi|39777610 semaphorin 4B precursor [Homo sapiens] 62 5e-09
gi|39777608 semaphorin 4B precursor [Homo sapiens] 62 5e-09
gi|28872814 semaphorin 4G [Homo sapiens] 58 8e-08
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 52 5e-06
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 52 5e-06
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 52 5e-06
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 52 5e-06
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 52 5e-06
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 52 7e-06
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 50 3e-05
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 50 3e-05
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 3787 bits (9820), Expect = 0.0
Identities = 1871/1871 (100%), Positives = 1871/1871 (100%)
Query: 1 MPSVCLLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNL 60
MPSVCLLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNL
Sbjct: 1 MPSVCLLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNL 60
Query: 61 TELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGIC 120
TELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGIC
Sbjct: 61 TELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGIC 120
Query: 121 QFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGKSEYFPT 180
QFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGKSEYFPT
Sbjct: 121 QFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGKSEYFPT 180
Query: 181 LSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLT 240
LSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLT
Sbjct: 181 LSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLT 240
Query: 241 LQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKP 300
LQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKP
Sbjct: 241 LQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKP 300
Query: 301 GLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGE 360
GLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGE
Sbjct: 301 GLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGE 360
Query: 361 GTLALPWLLNKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAY 420
GTLALPWLLNKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAY
Sbjct: 361 GTLALPWLLNKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAY 420
Query: 421 TYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSE 480
TYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSE
Sbjct: 421 TYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSE 480
Query: 481 KQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCV 540
KQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCV
Sbjct: 481 KQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCV 540
Query: 541 QVRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQ 600
QVRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQ
Sbjct: 541 QVRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQ 600
Query: 601 ELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYR 660
ELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYR
Sbjct: 601 ELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYR 660
Query: 661 HTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYE 720
HTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYE
Sbjct: 661 HTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYE 720
Query: 721 CVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFR 780
CVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFR
Sbjct: 721 CVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFR 780
Query: 781 ALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHP 840
ALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHP
Sbjct: 781 ALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHP 840
Query: 841 RITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEMEE 900
RITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEMEE
Sbjct: 841 RITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEMEE 900
Query: 901 SLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSL 960
SLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSL
Sbjct: 901 SLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSL 960
Query: 961 DAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYT 1020
DAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYT
Sbjct: 961 DAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYT 1020
Query: 1021 QDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCK 1080
QDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCK
Sbjct: 1021 QDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCK 1080
Query: 1081 APGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKP 1140
APGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKP
Sbjct: 1081 APGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKP 1140
Query: 1141 GSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGG 1200
GSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGG
Sbjct: 1141 GSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGG 1200
Query: 1201 LEFWLGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQM 1260
LEFWLGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQM
Sbjct: 1201 LEFWLGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQM 1260
Query: 1261 DNLESRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKEL 1320
DNLESRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKEL
Sbjct: 1261 DNLESRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKEL 1320
Query: 1321 DTPPNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYAT 1380
DTPPNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYAT
Sbjct: 1321 DTPPNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYAT 1380
Query: 1381 GLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLY 1440
GLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLY
Sbjct: 1381 GLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLY 1440
Query: 1441 CAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNC 1500
CAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNC
Sbjct: 1441 CAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNC 1500
Query: 1501 DSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLN 1560
DSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLN
Sbjct: 1501 DSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLN 1560
Query: 1561 SLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITP 1620
SLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITP
Sbjct: 1561 SLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITP 1620
Query: 1621 DQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTA 1680
DQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTA
Sbjct: 1621 DQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTA 1680
Query: 1681 HRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHK 1740
HRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHK
Sbjct: 1681 HRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHK 1740
Query: 1741 NSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMAS 1800
NSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMAS
Sbjct: 1741 NSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMAS 1800
Query: 1801 ISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKL 1860
ISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKL
Sbjct: 1801 ISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKL 1860
Query: 1861 EQIISLVSSDS 1871
EQIISLVSSDS
Sbjct: 1861 EQIISLVSSDS 1871
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 2550 bits (6608), Expect = 0.0
Identities = 1249/1859 (67%), Positives = 1482/1859 (79%), Gaps = 11/1859 (0%)
Query: 22 PFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPP 81
PFR F +D LTHL VH TGEV+VGAVNR++KL+ NLT LRAHVTGPVEDN +CYPPP
Sbjct: 17 PFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPP 76
Query: 82 SMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHY 141
S++ C H L DN+NKLLL+DYAA RL+ACGS QGICQFLRLDDLFKLGEPHHRKEHY
Sbjct: 77 SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHY 136
Query: 142 LSGAQEPDSMAGVIVE--QGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLV 199
LS QE SMAGV++ GQG +KLFVGT +DGKSEYFPTLSSR+L+++E+ ADMF V
Sbjct: 137 LSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFV 196
Query: 200 YQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFT 259
YQDEFVSSQ+KIPSDTLS +PAFDIYY+Y F S FVY+LTLQLDTQ T D AGE FFT
Sbjct: 197 YQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFT 256
Query: 260 SKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFT 319
SKIVR+C D +FYSYVEFPIGC GVEYRLVQ A+L++PG LA LG+ DEDVLFT
Sbjct: 257 SKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFT 316
Query: 320 IFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTP 379
+F+QGQKNR PP+++ LCLFTL I I+ RIQSCYRGEG L+LPWLLNKEL CIN+P
Sbjct: 317 VFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSP 376
Query: 380 MQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKK 439
+QI+ +FCG NQPLGG IEG PL D DG+ +VAAY YR +VVF GTRSG ++K
Sbjct: 377 LQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRK 436
Query: 440 VRVD----GFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQ 495
+ VD G + A YE+V +GSPILRDL+ SP+H+++Y ++EKQV+++PVE+C QY
Sbjct: 437 ILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYT 496
Query: 496 SCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPG 555
SC CLGS DPHCGWCVL C R AC A P FA +L +CVQ+ V+P NVSVT
Sbjct: 497 SCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQCVQLTVQPRNVSVTMSQ 556
Query: 556 VQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTV 615
V L + NVPDLSAGV+C+FE E+E+VL G + C SPS +E+ +TRG G R V
Sbjct: 557 VPLVLQAWNVPDLSAGVNCSFEDFTESESVL-EDGRIHCRSPSAREVAPITRGQGDQRVV 615
Query: 616 RLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEG 675
+L L SKETG +FA DFVFYNCSV QSC+SCV +PCHWCKYRH CT +C+F EG
Sbjct: 616 KLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYRHVCTHNVADCAFLEG 675
Query: 676 RVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAV 735
RV+ E CP+ILPS + +PVGV++P+TL A+NLPQPQSGQ+ YEC+ + G RV A+
Sbjct: 676 RVNVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTAL 735
Query: 736 RFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGL 795
RFNSSS+QCQN+SYSYEG++ D ++ SVVW+G+F ID P + +A LYKC A R SCGL
Sbjct: 736 RFNSSSLQCQNSSYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGL 795
Query: 796 CLKADPRFNCGWCISEHRCQLRTHCPAPK-TNWMHLSQKGTRCSHPRITQIHPLVGPKEG 854
CLKADPRF CGWC++E RC LR HC A +WMH +RC+ P+I ++ P GP++G
Sbjct: 796 CLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQG 855
Query: 855 GTRVTIVGDNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVE 912
GTR+TI G+NLGL +V G+RV V C+ + +EYISAE+IVCE+ ++ VE
Sbjct: 856 GTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVE 915
Query: 913 LCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRD 972
+CV DCS +R S + ++FVTPTF +VSPSRGP SGGT + I GS L+AGS V V+V
Sbjct: 916 VCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGG 975
Query: 973 SECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTW 1032
C F R+++ I C++P P API + I+RA +++P + Y YT+DPT+ R++P W
Sbjct: 976 RPCSFSWRNSREIRCLTPPGQ-SPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEW 1034
Query: 1033 SIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPR 1092
SI +G T +TV+GT+L TV+EPR+RAKY GIE N C V NDT M+C+AP + P
Sbjct: 1035 SINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPP 1094
Query: 1093 AQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLI 1152
GE PDE GF++D+V++ LN +SF YYPDP EPL P+G+L++KP S ++LKG+NL+
Sbjct: 1095 ELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNLL 1154
Query: 1153 PAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISA 1212
P A G+SRLNYTVLIG PC+LTVS+TQLLC++P+ TG+ V V GG EF GTL + +
Sbjct: 1155 PPAPGNSRLNYTVLIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRAGGFEFSPGTLQVYS 1214
Query: 1213 ERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECK 1272
+ LTLPA++G+ GGGLLLL I AVL+AYKRK++DADRTLKRLQLQMDNLESRVALECK
Sbjct: 1215 DSLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECK 1274
Query: 1273 EAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTPPNVEKALRL 1332
EAFAELQTDI+ELTN +D IPFLDYRTYA+RVLFPGIE HPVLKE++ NVEK+L L
Sbjct: 1275 EAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLFPGIEDHPVLKEMEVQANVEKSLTL 1334
Query: 1333 FGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIE 1392
FGQLL + F+LTFI TLEAQ SFSMRDRG VASL M ALQ ++YATG+LKQLL+DLIE
Sbjct: 1335 FGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIE 1394
Query: 1393 KNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPI 1452
KNLESKNHPKLLLRRTESVAEKMLTNWFTFLL+KFLKECAGEPLF+LYCAIKQQMEKGPI
Sbjct: 1395 KNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPI 1454
Query: 1453 DAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLD 1512
DAITGEARYSLSEDKLIRQQIDYKTLTL+CV PENE + +VPVK L+CD++TQAK+KLLD
Sbjct: 1455 DAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGLDCDTVTQAKEKLLD 1514
Query: 1513 TVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSL 1572
YKG+PYSQRPKA DMDLEWRQGRM RIILQDEDVTTKI+ DWKRLN+LAHYQVTDGS
Sbjct: 1515 AAYKGVPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSS 1574
Query: 1573 VALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLV 1632
VALVPKQ SAYN++NS TFT+SLSRYES+LRTASSPDSLRSR PMITPD E+GTKLWHLV
Sbjct: 1575 VALVPKQTSAYNISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLV 1634
Query: 1633 KNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKY 1692
KNHDH D REGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFET+FSTAHRGSALPLAIKY
Sbjct: 1635 KNHDHLDQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKY 1694
Query: 1693 MFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVA 1752
MFDFLDEQAD+ QI D DVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVA
Sbjct: 1695 MFDFLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVA 1754
Query: 1753 QTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVE 1812
QTFMDSCSTSEH+LGKDSPSNKLLYAKDIPNYKSWVERYY DIAKM +ISDQDM AYL E
Sbjct: 1755 QTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAE 1814
Query: 1813 QSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS 1871
QSRLH S F+ +SAL+E+Y Y+TKY+ EIL AL++D R+ +LR KLEQ++ ++ S
Sbjct: 1815 QSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQVVDTMALSS 1873
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 2306 bits (5975), Expect = 0.0
Identities = 1122/1846 (60%), Positives = 1412/1846 (76%), Gaps = 13/1846 (0%)
Query: 35 HLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVD 94
HL V TG +++GAVNR++KL+ +L L H TGP EDN +CYPP ++ C L +
Sbjct: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
Query: 95 NINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGV 154
N+NK+LLIDY RL+ACGS++QGIC+ LRL+DLFKLGEP+H+KEHYLSG E S+ GV
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGV 172
Query: 155 IVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214
IV KLF+ TAVDGK EYFPT+SSRKL + ++ MF+ V+ DEFV+S IKIPSD
Sbjct: 173 IVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSD 232
Query: 215 TLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYS 274
T ++ P FDIYY+YGF S +FVYFLTLQ + T E+ +TSK+VR+C D+ F S
Sbjct: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNS 292
Query: 275 YVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ 334
YVE PIGC GVEYRL+Q+A+L+K G +L + LGV D+D+LFT+FS+GQK + +
Sbjct: 293 YVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDE 352
Query: 335 TILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQP 394
+ LC+F L IN I+ R+QSCYRGEGTL L WL K++PC + + I+ NFCGL +N P
Sbjct: 353 SALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAP 412
Query: 395 LGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQ-DAHLYET 453
LG ++ G+P+ + D M SV AY Y+ HS+ F+GT+SG LKK+RVDG + +A YET
Sbjct: 413 LGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYET 472
Query: 454 VPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVL 513
V VVD P+LRD+ FS DH +Y++SE+Q++++PVE+C QYQSC CLGSGDPHCGWCVL
Sbjct: 473 VQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVL 532
Query: 514 RHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVS 573
+ C R+ C + P FA E+ +CV++ V PNN+SV+ V L + +NVP+LSAGV+
Sbjct: 533 HNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNVPELSAGVN 592
Query: 574 CAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADF 633
C FE +E + L+ ++ C SP+ +E+ + +G V+LQL SKETG+ FA F
Sbjct: 593 CTFEDLSEMDG-LVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSF 651
Query: 634 VFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLL 693
VFYNCSV SC+SCV SPY CHWCKYRH CT P CSFQEGRV PE CP++L +L
Sbjct: 652 VFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVDKIL 711
Query: 694 IPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEG 753
+PV V++P+TL+AKNLPQPQSGQ+ YEC++ +QG +QRVPA+RFNSSSVQCQN SYSYEG
Sbjct: 712 VPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTSYSYEG 771
Query: 754 DEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCGWCISEHR 813
E + ++ +VVW+G F ID P + LYKC A R SCGLCLKADP F CGWC +
Sbjct: 772 MEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQ 831
Query: 814 CQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVG 873
C LR HCPA ++ W+ LS ++C++PRIT+I P+ GP+EGGT+VTI G+NLGL R++
Sbjct: 832 CTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIA 891
Query: 874 --LRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYS 931
++VAGV C+ + YI AE+IVCEM E+ PS G VE+CV C +F +S Q+Y
Sbjct: 892 SHVKVAGVECSPLVDGYIPAEQIVCEMGEA-KPSQHAGFVEICVAVCRPEFMARSSQLYY 950
Query: 932 FVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKAIVCISPL 991
F+T T + PSRGP SGGT++TI+G++L+AGS V V C F RR IVC +
Sbjct: 951 FMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVC-NTT 1009
Query: 992 STLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTV 1051
S+ + +++ +DRA I L++ Y +DPT+ R+EP WSI++G+T I V GTHL +
Sbjct: 1010 SSDEVLEMKVSVQVDRAKIHQ-DLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLI 1068
Query: 1052 QEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTA 1111
Q P++RAK+ G E N C+V+N T M C+AP + LG E P+EFGF+LD+VQ+
Sbjct: 1069 QNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSL 1128
Query: 1112 RSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSS-RLNYTVLIGGQ 1170
LN+++FTYYP+P FE GPSG+L++KPG+ ++LKGKNLIP AG + +LNYTVL+G +
Sbjct: 1129 LILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEK 1188
Query: 1171 PCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGL 1230
PC++TVSD QLLC+SP+ GR VM VGG+E+ G ++I+ + L+LPA++ +A GGL
Sbjct: 1189 PCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSIAVAGGL 1248
Query: 1231 LLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINELTNHMD 1290
L++ I AVL+AYKRK++++D TLKRLQ+QMDNLESRVALECKEAFAELQTDI+ELT+ +D
Sbjct: 1249 LIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLD 1308
Query: 1291 EVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP----PNVEKALRLFGQLLHSRAFVLTF 1346
IPFLDYRTY +RVLFPGIE HPVL++L+ P VEK L+LF QL++++ F+L+F
Sbjct: 1309 GAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSF 1368
Query: 1347 IHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKNHPKLLLR 1406
I TLE+Q SFSMRDRG VASL M LQS+L+YAT +LKQLLADLI+KNLESKNHPKLLLR
Sbjct: 1369 IRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLR 1428
Query: 1407 RTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEARYSLSED 1466
RTESVAEKMLTNWFTFLL+KFLKECAGEPLF L+CAIKQQMEKGPIDAITGEARYSLSED
Sbjct: 1429 RTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSED 1488
Query: 1467 KLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLDTVYKGIPYSQRPKA 1526
KLIRQQIDYKTL L CV P+N S +VPVK+LNCD+ITQ K+K+LD ++K +P S RPKA
Sbjct: 1489 KLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKA 1548
Query: 1527 EDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALVPKQVSAYNMA 1586
DMDLEWRQG R+ILQDED+TTKIE DWKRLN+LAHYQV DGS+VALV KQV+AYN
Sbjct: 1549 ADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAV 1608
Query: 1587 NSFTFTR-SLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLVKNHDHADHREGDR 1645
N+ T +R S S+YE+++R SPDSLRSR PMITPD E+G K+WHLVKNH+H D +EGDR
Sbjct: 1609 NNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGDQKEGDR 1668
Query: 1646 GSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKYMFDFLDEQADQRQ 1705
GSKMVSEIYLTRLLATKGTLQKFVDDLFET+FSTAHRGSALPLAIKYMFDFLDEQAD+
Sbjct: 1669 GSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHG 1728
Query: 1706 ISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHR 1765
I DP VRHTWKSNCLPLRFWVN+IKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHR
Sbjct: 1729 IHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHR 1788
Query: 1766 LGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVEQSRLHASDFSVLS 1825
LGKDSPSNKLLYAKDIP+YK+WVERYY DI KM +ISDQDM+AYL EQSR+H ++F+ +S
Sbjct: 1789 LGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMS 1848
Query: 1826 ALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS 1871
AL+E++ YV KY +EIL LD D C K KL KLEQ+I+L+S DS
Sbjct: 1849 ALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1894
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 2268 bits (5877), Expect = 0.0
Identities = 1117/1852 (60%), Positives = 1402/1852 (75%), Gaps = 14/1852 (0%)
Query: 30 DTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHR 89
D T HL VH+ TG V+VGA+NRV+KL NLT AH TGP EDN CYPP ++ C+
Sbjct: 47 DWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPEEDNKSCYPPLIVQPCSEV 106
Query: 90 LAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPD 149
L +N+NKLL+IDY+ RL+ACGS++QG+C+ LRLDDLF L EP H+KEHYLS +
Sbjct: 107 LTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTG 166
Query: 150 SMAGVIVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQI 209
+M GVIV KLF+GTAVDGK +YFPTLSSRKL D +S+ M +FVSS I
Sbjct: 167 TMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLI 226
Query: 210 KIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTL-LDTAGEKFFTSKIVRMCAG 268
KIPSDTL+L FDI+YIYGF S FVYFLT+Q +T + + +++AG+ F+TS+IVR+C
Sbjct: 227 KIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKD 286
Query: 269 DSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNR 328
D +F+SYV P GC+ GVEYRL+Q+A+LAKPG LAQA + + +DVLF IFS+GQK
Sbjct: 287 DPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQY 346
Query: 329 ASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCG 388
PP + LC F + IN I+ R+QSCY+GEG L L WLL K++ C P+ I+ NFCG
Sbjct: 347 HHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWLLGKDVQCTKAPVPIDDNFCG 406
Query: 389 LVLNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDA 448
L +NQPLGG +EGL L S D M SVA+Y Y +SVVF+GT+SG LKK+R DG
Sbjct: 407 LDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHG 466
Query: 449 HL-YETVPVV-DGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDP 506
+ YE V V+ DGSPILRD+ FS D R++Y++SE+QV+++PVE+CEQY +C CL SGDP
Sbjct: 467 GVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDP 526
Query: 507 HCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTVTLHNVP 566
HCGWC L + C R C A P+ FA +S+CV + V P+++SV+ L++ + + P
Sbjct: 527 HCGWCALHNMCSRRDKCQQAWEPNRFAASISQCVSLAVHPSSISVSEHSRLLSLVVSDAP 586
Query: 567 DLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGV 626
DLSAG++CAF E E + S +++C SP +++ + + LQL SKETG
Sbjct: 587 DLSAGIACAFGNLTEVEGQVSGS-QVICISPGPKDVPVIPLDQDWFG-LELQLRSKETGK 644
Query: 627 RFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEI 686
F +F FYNCS Q C+SCV S + CHWCKYR+ CT P CSFQEGR++ E CP++
Sbjct: 645 IFVSTEFKFYNCSAHQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQL 704
Query: 687 LPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQN 746
+P+ ++LIPVG ++P+TL+A+NLPQPQSGQ+ YECV+ +QG RVPA+RFNSSSVQCQN
Sbjct: 705 VPTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQN 764
Query: 747 ASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCG 806
+SY Y+G + + +DF+VVW+G+F ID P + LYKC AQR SCGLCLKAD +F CG
Sbjct: 765 SSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFECG 824
Query: 807 WCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLG 866
WC E RC L HC +P + W+ S +CS+P+IT+I + GP EGGTRVTI G NLG
Sbjct: 825 WCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLG 884
Query: 867 LLSREVG--LRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRT 924
L E+ ++VAGV C +P EYI AE+IVCEM +LV + GPV LC+G+C +F T
Sbjct: 885 LDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGTTS-GPVRLCIGECKPEFMT 943
Query: 925 QSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKA 984
+S Q Y+FV P+ ++P RGP SGGT +TI+G L AGS V V + + C+F R
Sbjct: 944 KSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSE 1003
Query: 985 IVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVS 1044
IVC+SP S+ G P+++++DRA++ S L + Y DP V R+EP WSI +G T +T++
Sbjct: 1004 IVCVSPPSSNGLGPVPVSVSVDRAHVDS-NLQFEYIDDPRVQRIEPEWSIASGHTPLTIT 1062
Query: 1045 GTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFL 1104
G +L +QEPR+R K+ G E+ N C+V+N T + C AP + E PDEFGF+
Sbjct: 1063 GFNLDVIQEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFV 1122
Query: 1105 LDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYT 1164
++VQ+ N + F YYP+P+FE L P+GVLD KPGS ++LKGKNL P A+G ++LNYT
Sbjct: 1123 FNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYT 1182
Query: 1165 VLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGL 1224
VLIG PC++TVS+TQLLC+ P+ TG+ VMV VGG+ F G++ + ++ LTLPA++ +
Sbjct: 1183 VLIGETPCAVTVSETQLLCEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIVSI 1242
Query: 1225 AAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINE 1284
AAGG LLL+ + VL+AYKRK+++ D TLKRLQ+QMDNLESRVALECKEAFAELQTDINE
Sbjct: 1243 AAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINE 1302
Query: 1285 LTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTPPN----VEKALRLFGQLLHSR 1340
LT+ +D IP+LDYRTYA+RVLFPGIE HPVL+EL+ N VEKAL+LF QL++++
Sbjct: 1303 LTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLINNK 1362
Query: 1341 AFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKNH 1400
F+LTFI TLE Q SFSMRDRG VASL M LQ RL+YAT +LKQLL+DLI+KNLE+KNH
Sbjct: 1363 VFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNH 1422
Query: 1401 PKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEAR 1460
PKLLLRRTESVAEKMLTNWF FLLHKFLKECAGEPLF+LYCAIKQQMEKGPIDAITGEAR
Sbjct: 1423 PKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEAR 1482
Query: 1461 YSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLDTVYKGIPY 1520
YSLSEDKLIRQQI+YKTL L+CV P+NE S ++PVKVLNCD+ITQ K+K+LD VYK +PY
Sbjct: 1483 YSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPY 1542
Query: 1521 SQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALVPKQV 1580
SQRP+A DMDLEWRQGR+ R++LQDED+TTKIE DWKRLN+L HYQV+D S+VALVPKQ
Sbjct: 1543 SQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQT 1602
Query: 1581 SAYNMANSFTFTR-SLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLVKNHDHAD 1639
S+YN+ S + +R S+SRY+S R SPDSLRSRAPMITPD E+G K+WHLVKNHDH D
Sbjct: 1603 SSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLESGVKVWHLVKNHDHGD 1662
Query: 1640 HREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKYMFDFLDE 1699
+EGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFET+FST HRGSALPLAIKYMFDFLDE
Sbjct: 1663 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDE 1722
Query: 1700 QADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1759
QAD+ I D DVRHTWKSNCLPLRFWVNVIKNPQFVFDIHK SITDACLSVVAQTFMDSC
Sbjct: 1723 QADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSC 1782
Query: 1760 STSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVEQSRLHAS 1819
STSEHRLGKDSPSNKLLYAKDIP+YKSWVERYY DIAK+ +ISDQDM+AYL EQSRLHA
Sbjct: 1783 STSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAISDQDMNAYLAEQSRLHAV 1842
Query: 1820 DFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS 1871
+F++LSALNE+Y YV+KY +E++ AL++D R+ +L K+EQ+I+ +S +S
Sbjct: 1843 EFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYKVEQLINAMSIES 1894
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 913 bits (2359), Expect = 0.0
Identities = 645/1988 (32%), Positives = 976/1988 (49%), Gaps = 232/1988 (11%)
Query: 4 VCLLLLLF----LAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPN 59
+CLLLLL L + GA F +TTL HLA+ G ++VGAVNR+F+L+P
Sbjct: 50 LCLLLLLLSPPPLPLTGA------HRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPE 103
Query: 60 LTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGI 119
L VTGPV D+ C P C DN N+LLL+ A+ LVACG + QG+
Sbjct: 104 LQLEAVAVTGPVIDSPDCVPFRDPAECPQAQL-TDNANQLLLVSSRAQELVACGQVRQGV 162
Query: 120 CQFLRLDDLFK-LGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGK-SEY 177
C+ RL D+ + L + + A P +V G L V + GK S
Sbjct: 163 CETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAG 222
Query: 178 FPTLSSRKLISDE--DSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASF 235
P L+ R+L + S + LV D + ++ Y+ F A
Sbjct: 223 VPPLAIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARS 266
Query: 236 VYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSA 295
YF+ + + + + S + R+C GD+ YSYVE P+ C +G L+Q+A
Sbjct: 267 AYFVFRRRGAR-------AQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAA 315
Query: 296 HLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQS 355
LA PG LL +F+ G + Q LC F + + A + + +
Sbjct: 316 FLA-PGTLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRL 355
Query: 356 CY----RG-EGTLALPWLLNKELPCINTPMQINGNF-CGLVLN-QPLGGLHVIEGLPLLA 408
CY RG G C+ P+ ++ CG P+ G +E PLL
Sbjct: 356 CYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLK 415
Query: 409 DSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLF 468
+++VAA H + F+G G L KV + G Q + GS I DLL
Sbjct: 416 LGQP-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLL 474
Query: 469 SPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASA 528
H+Y+L+ QV ++PV C Q+ CA+CL + DP CGWCVL+ RC R+G C A
Sbjct: 475 DSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQ 534
Query: 529 PHGFA---EELSKCVQVR-VRPNNVSVTSPGVQLTVTLHNVPDLSAG--VSCAFEAAAEN 582
+ + EE S C+ ++ + P + G Q+T+++ +P L A CAF +
Sbjct: 535 LNQWLWSYEEDSHCLHIQSLLPGHHPRQEQG-QVTLSVPRLPILDADEYFHCAF---GDY 590
Query: 583 EAVLLPSG-ELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVL 641
+++ G + C +P ++ G TV L L+ ++ V A +F FY+CS +
Sbjct: 591 DSLAHVEGPHVACVTPPQDQVPLNPPGTDHV-TVPLALMFEDVTV--AATNFSFYDCSAV 647
Query: 642 QS------CMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHS----------PEGCPE 685
Q+ C +CVGS + CHWC C H C E ++S P CP+
Sbjct: 648 QALEAAAPCRACVGSIWRCHWCPQSSHCVYGEH-CPEGERTIYSAQEVDIQVRGPGACPQ 706
Query: 686 ILP-SGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAV----RFNSS 740
+ +G L+PVG L LR +NL + ++ C + + G + +PA +S
Sbjct: 707 VEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSG 766
Query: 741 SVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKAD 800
+ CQ A Y + + V +D + +LY C P C C A+
Sbjct: 767 LIHCQ-AHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAAN 825
Query: 801 PRFNCGWCIS-EHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVT 859
C WC + C+ CP + C P I + PL GP EGG +T
Sbjct: 826 RSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLALT 877
Query: 860 IVGDNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGD 917
I+G NLG +V + VA CN P+ Y ++ RIVC S P+ GPV + +
Sbjct: 878 ILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVT--SPAPNGTTGPVRVAIKS 935
Query: 918 CSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQF 977
S Q +++ P +SP GP +GGT+LTI G L G + V C
Sbjct: 936 QPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPI 992
Query: 978 VRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIING 1037
+ + P +A + + A + + YT +P + EP+ S G
Sbjct: 993 LEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGG 1052
Query: 1038 STAITVSGTHLLTVQEPRV-------------RAKYRG---------------------- 1062
I V GT L VQ P + RA+ +
Sbjct: 1053 GRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGG 1112
Query: 1063 --IETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQT--ARSLNRSS 1118
++ + C V + + +LC++P + HP F LD+VQ A +
Sbjct: 1113 GLLQCSTVCSVNSSSLLLCRSPAV--------PDRAHPQRVFFTLDNVQVDFASASGGQG 1164
Query: 1119 FTYYPDPSFEPL---GPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL- 1174
F Y P+P PL GP+ +KPG + ++G+ L G S+ V IG C +
Sbjct: 1165 FLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVK 1221
Query: 1175 TVSDTQLLCDSPSQ-------TGRQPVMVLVGGLEFWLGTLHISAERALT---LPAMMGL 1224
T++ T L C+ P+ +G +V +G ++ LG + AE L+ + A G+
Sbjct: 1222 TLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGV 1281
Query: 1225 AAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINE 1284
G +L+ A+ + + Y+ K++ A R +++ +Q+++LE+ V +C++ F +L T++ +
Sbjct: 1282 GMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTD 1341
Query: 1285 LTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP------PNVEKALRLFGQLLH 1338
L++ ++ IPFLDYRTYA R FPG P+ + + P V + L LL+
Sbjct: 1342 LSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLN 1401
Query: 1339 SRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESK 1398
S+ F+LT IHTLE Q SFS RDR VASL +AL +L+Y T +++ LL DL +
Sbjct: 1402 SKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH-- 1459
Query: 1399 NHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGE 1458
+PKL+LRRTE++ EK+LTNW + L+ FL+E AGEPL++L+ AI+ Q++KGP+DA+TG+
Sbjct: 1460 RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGK 1519
Query: 1459 ARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSA-------QVPVKVLNCDSITQAKDKLL 1511
A+ +L++ +L+R+ ++++ LTL + G A +VP +VL+ D+ITQ K+K+L
Sbjct: 1520 AKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVL 1579
Query: 1512 DTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGS 1571
D VYKG P+SQRP +DLEWR G + L DED+T+ + WKRLN+L HY+V DG+
Sbjct: 1580 DQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGA 1639
Query: 1572 LVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHL 1631
V LVP+ L R ++ ++ + L P + +E G LWHL
Sbjct: 1640 TVGLVPQ----------------LHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHL 1683
Query: 1632 VKNHDHAD----------HREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAH 1681
VK + + RE R +K + EIYLTRLL+ KGTLQKFVDD F+ + S
Sbjct: 1684 VKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV-- 1740
Query: 1682 RGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKN 1741
+P+A+KY+FD LDE A++ I DP H WK+N L LRFWVN +KNPQ +FD+ +
Sbjct: 1741 -NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVS 1799
Query: 1742 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASI 1801
DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK VERYY DI + +
Sbjct: 1800 DNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPA 1859
Query: 1802 SDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLE 1861
S Q+M++ L E S + S L AL ELY ++ +Y +I++AL+ D +K +L +L+
Sbjct: 1860 SYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQ 1919
Query: 1862 QIISLVSS 1869
Q+ +LV +
Sbjct: 1920 QVAALVEN 1927
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 913 bits (2359), Expect = 0.0
Identities = 645/1988 (32%), Positives = 976/1988 (49%), Gaps = 232/1988 (11%)
Query: 4 VCLLLLLF----LAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPN 59
+CLLLLL L + GA F +TTL HLA+ G ++VGAVNR+F+L+P
Sbjct: 27 LCLLLLLLSPPPLPLTGA------HRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPE 80
Query: 60 LTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGI 119
L VTGPV D+ C P C DN N+LLL+ A+ LVACG + QG+
Sbjct: 81 LQLEAVAVTGPVIDSPDCVPFRDPAECPQAQL-TDNANQLLLVSSRAQELVACGQVRQGV 139
Query: 120 CQFLRLDDLFK-LGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGK-SEY 177
C+ RL D+ + L + + A P +V G L V + GK S
Sbjct: 140 CETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAG 199
Query: 178 FPTLSSRKLISDE--DSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASF 235
P L+ R+L + S + LV D + ++ Y+ F A
Sbjct: 200 VPPLAIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARS 243
Query: 236 VYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSA 295
YF+ + + + + S + R+C GD+ YSYVE P+ C +G L+Q+A
Sbjct: 244 AYFVFRRRGAR-------AQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAA 292
Query: 296 HLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQS 355
LA PG LL +F+ G + Q LC F + + A + + +
Sbjct: 293 FLA-PGTLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRL 332
Query: 356 CY----RG-EGTLALPWLLNKELPCINTPMQINGNF-CGLVLN-QPLGGLHVIEGLPLLA 408
CY RG G C+ P+ ++ CG P+ G +E PLL
Sbjct: 333 CYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLK 392
Query: 409 DSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLF 468
+++VAA H + F+G G L KV + G Q + GS I DLL
Sbjct: 393 LGQP-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLL 451
Query: 469 SPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASA 528
H+Y+L+ QV ++PV C Q+ CA+CL + DP CGWCVL+ RC R+G C A
Sbjct: 452 DSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQ 511
Query: 529 PHGFA---EELSKCVQVR-VRPNNVSVTSPGVQLTVTLHNVPDLSAG--VSCAFEAAAEN 582
+ + EE S C+ ++ + P + G Q+T+++ +P L A CAF +
Sbjct: 512 LNQWLWSYEEDSHCLHIQSLLPGHHPRQEQG-QVTLSVPRLPILDADEYFHCAF---GDY 567
Query: 583 EAVLLPSG-ELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVL 641
+++ G + C +P ++ G TV L L+ ++ V A +F FY+CS +
Sbjct: 568 DSLAHVEGPHVACVTPPQDQVPLNPPGTDHV-TVPLALMFEDVTV--AATNFSFYDCSAV 624
Query: 642 QS------CMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHS----------PEGCPE 685
Q+ C +CVGS + CHWC C H C E ++S P CP+
Sbjct: 625 QALEAAAPCRACVGSIWRCHWCPQSSHCVYGEH-CPEGERTIYSAQEVDIQVRGPGACPQ 683
Query: 686 ILP-SGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAV----RFNSS 740
+ +G L+PVG L LR +NL + ++ C + + G + +PA +S
Sbjct: 684 VEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSG 743
Query: 741 SVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKAD 800
+ CQ A Y + + V +D + +LY C P C C A+
Sbjct: 744 LIHCQ-AHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAAN 802
Query: 801 PRFNCGWCIS-EHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVT 859
C WC + C+ CP + C P I + PL GP EGG +T
Sbjct: 803 RSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLALT 854
Query: 860 IVGDNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGD 917
I+G NLG +V + VA CN P+ Y ++ RIVC S P+ GPV + +
Sbjct: 855 ILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVT--SPAPNGTTGPVRVAIKS 912
Query: 918 CSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQF 977
S Q +++ P +SP GP +GGT+LTI G L G + V C
Sbjct: 913 QPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPI 969
Query: 978 VRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIING 1037
+ + P +A + + A + + YT +P + EP+ S G
Sbjct: 970 LEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGG 1029
Query: 1038 STAITVSGTHLLTVQEPRV-------------RAKYRG---------------------- 1062
I V GT L VQ P + RA+ +
Sbjct: 1030 GRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGG 1089
Query: 1063 --IETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQT--ARSLNRSS 1118
++ + C V + + +LC++P + HP F LD+VQ A +
Sbjct: 1090 GLLQCSTVCSVNSSSLLLCRSPAV--------PDRAHPQRVFFTLDNVQVDFASASGGQG 1141
Query: 1119 FTYYPDPSFEPL---GPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL- 1174
F Y P+P PL GP+ +KPG + ++G+ L G S+ V IG C +
Sbjct: 1142 FLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVK 1198
Query: 1175 TVSDTQLLCDSPSQ-------TGRQPVMVLVGGLEFWLGTLHISAERALT---LPAMMGL 1224
T++ T L C+ P+ +G +V +G ++ LG + AE L+ + A G+
Sbjct: 1199 TLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGV 1258
Query: 1225 AAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINE 1284
G +L+ A+ + + Y+ K++ A R +++ +Q+++LE+ V +C++ F +L T++ +
Sbjct: 1259 GMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTD 1318
Query: 1285 LTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP------PNVEKALRLFGQLLH 1338
L++ ++ IPFLDYRTYA R FPG P+ + + P V + L LL+
Sbjct: 1319 LSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLN 1378
Query: 1339 SRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESK 1398
S+ F+LT IHTLE Q SFS RDR VASL +AL +L+Y T +++ LL DL +
Sbjct: 1379 SKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH-- 1436
Query: 1399 NHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGE 1458
+PKL+LRRTE++ EK+LTNW + L+ FL+E AGEPL++L+ AI+ Q++KGP+DA+TG+
Sbjct: 1437 RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGK 1496
Query: 1459 ARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSA-------QVPVKVLNCDSITQAKDKLL 1511
A+ +L++ +L+R+ ++++ LTL + G A +VP +VL+ D+ITQ K+K+L
Sbjct: 1497 AKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVL 1556
Query: 1512 DTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGS 1571
D VYKG P+SQRP +DLEWR G + L DED+T+ + WKRLN+L HY+V DG+
Sbjct: 1557 DQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGA 1616
Query: 1572 LVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHL 1631
V LVP+ L R ++ ++ + L P + +E G LWHL
Sbjct: 1617 TVGLVPQ----------------LHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHL 1660
Query: 1632 VKNHDHAD----------HREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAH 1681
VK + + RE R +K + EIYLTRLL+ KGTLQKFVDD F+ + S
Sbjct: 1661 VKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV-- 1717
Query: 1682 RGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKN 1741
+P+A+KY+FD LDE A++ I DP H WK+N L LRFWVN +KNPQ +FD+ +
Sbjct: 1718 -NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVS 1776
Query: 1742 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASI 1801
DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK VERYY DI + +
Sbjct: 1777 DNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPA 1836
Query: 1802 SDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLE 1861
S Q+M++ L E S + S L AL ELY ++ +Y +I++AL+ D +K +L +L+
Sbjct: 1837 SYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQ 1896
Query: 1862 QIISLVSS 1869
Q+ +LV +
Sbjct: 1897 QVAALVEN 1904
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 893 bits (2307), Expect = 0.0
Identities = 628/1940 (32%), Positives = 957/1940 (49%), Gaps = 190/1940 (9%)
Query: 6 LLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRA 65
L LL L G +L R F ++ L HLAV +G V++GAVN +++L L +
Sbjct: 8 LTLLGLLGAGASLRPRKLD-FFRSEKELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66
Query: 66 HVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRL 125
TGP DN +C PP C H DN+N+LLL+D +RLV CGS+++GIC L
Sbjct: 67 VATGPALDNKKCTPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125
Query: 126 DD--LFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSK-LFVGTAVDGKSEYFPTLS 182
+ L E ++ +++ E + G++ G G + LFVG +G + +S
Sbjct: 126 SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKG-NGPHDNGIIVS 184
Query: 183 SRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQ 242
+R L+ DS + F Y D + ++T AF+ +V+F+ Q
Sbjct: 185 TR-LLDRTDSREAFE-AYTDHATYKAGYLSTNTQQFVAAFE--------DGPYVFFVFNQ 234
Query: 243 LDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGL 302
D T + RMC D +YSY+E + C + H A G
Sbjct: 235 QDKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDI--------HAAAFGT 278
Query: 303 LLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRG--E 360
LA ++ P VL+ +FS+ ++ P LCLF L ++A + +CY G E
Sbjct: 279 CLAASVAAPGSGRVLYAVFSRDSRSSGGPGAG--LCLFPLDKVHAKMEANRNACYTGTRE 336
Query: 361 GTLALPWLLNKELPCINTPMQINGNF-CGLV-LNQPLGGLHVIEGLPLLADSTDGMASVA 418
+ ++ C + +F CG L PLG + G +L + +V
Sbjct: 337 ARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVT 396
Query: 419 AYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLL 478
H+V F+GT G + KV + + Y+++ V + RDL+ S D +Y +
Sbjct: 397 VAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAM 456
Query: 479 SEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGAS-APHGFAEELS 537
++ +V +LPV+ C Y +C C S DP+CGWCV+ RC R+ C A A H
Sbjct: 457 TQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSK 516
Query: 538 KCVQVR-VRPNNVSVTSPG-VQLTVTLHNVPDLSA--------GVSCAFEAAAENEAVLL 587
CV V +P N+S + G VQLTV+ +P LS G S A E EAV+
Sbjct: 517 SCVAVTSAQPQNMSRRAQGEVQLTVS--PLPALSEEDELLCLFGESPPHPARVEGEAVI- 573
Query: 588 PSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQS---- 643
C SPS + + H A V +QLL + + + FY+C S
Sbjct: 574 ------CNSPSSIPVTPPGQDHVA---VTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEEN 624
Query: 644 --CMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQP 701
C+SCV + + C W H C R H + CP+ L L+IP+
Sbjct: 625 LPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETD 684
Query: 702 LTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTEL 761
+ + KNL + + V + P S + + S++ +E L
Sbjct: 685 VNFQGKNLDTVKGSSLH----VGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHL 740
Query: 762 DFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCP 821
+ + + LY C R C LC A+P + C WC + RC C
Sbjct: 741 -----YVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCN 795
Query: 822 APKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVG-LRVAGVR 880
+ C P IT+I P GP GG R+TI+G NLG+ + ++ + VAG
Sbjct: 796 TT-----------SECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISVAGRN 844
Query: 881 CNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQV 940
C+ P Y + RIVC +E + +P G VE+ V R+ ++F P V
Sbjct: 845 CSFQPERYSVSTRIVCVIEAA--ETPFTGGVEVDVFGKLG--RSPPNVQFTFQQPKPLSV 900
Query: 941 SPSRGPASGGTRLTISGSSLDAGSR--VTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQ 998
P +GP +GGT LTI G+ LD GS+ V VT+ C+ + A+ P +T G Q
Sbjct: 901 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRG--Q 958
Query: 999 APITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQE----- 1053
+ ++ + + +PG+ +TY ++P + EP S +G +I V+G +Q
Sbjct: 959 MLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVV 1018
Query: 1054 ----------PRVRAKYRGIETTNTCQVI-NDTAMLCKAPGIFLGRPQPRAQGEHPDEFG 1102
PR + + T V NDT ++ +P + E P+ +
Sbjct: 1019 IAEPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAV----------PEEPEAYN 1068
Query: 1103 F-LLDHVQTARSLNRS---SFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGS 1158
+L + R+L R+ +F Y PDP+FE +G + + + +G NL A
Sbjct: 1069 LTVLIEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNLNKAMTLQ 1126
Query: 1159 SRLNYTVLIGGQPCSL-TVSDTQLLCDSPS------------QTGRQPVMVLVGGLEFW- 1204
+G + C++ T+++T L C+ P T P ++ G W
Sbjct: 1127 EA---EAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWV 1183
Query: 1205 LGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLE 1264
LG + R +P + L +++ I + Y RK+Q A+R ++++ Q++ LE
Sbjct: 1184 LGRVEYDT-RVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLE 1242
Query: 1265 SRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLF----PGIEAHPVLKEL 1320
V CK+ F +L ++ + TN + E IP LDY+TY RV F G + + +L
Sbjct: 1243 ESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKL 1302
Query: 1321 DTP----PNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRL 1376
D P P VE+AL F LL+S++F++ FIHTLE Q FS R + ASL VAL +L
Sbjct: 1303 DIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKL 1362
Query: 1377 DYATGLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPL 1436
+Y T ++ L +L+E+ + +KN PKL+LRR+E+V E+ML+NW + L+++LK+ AGEPL
Sbjct: 1363 EYYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPL 1421
Query: 1437 FLLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVK 1496
+ L+ AIK Q+EKGP+DA+ +A+Y+L++ L+ ++Y LT+ + ++EG +PVK
Sbjct: 1422 YKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIV-QDEGVDAIPVK 1480
Query: 1497 VLNCDSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDW 1556
VLNCD+I+Q K+K++D VY+G P S P+ + + LEWR G T IL D D+T++ E W
Sbjct: 1481 VLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGS-TAQILSDLDLTSQREGRW 1539
Query: 1557 KRLNSLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAP 1616
KR+N+L HY V DG+ + L VS S D R
Sbjct: 1540 KRVNTLMHYNVRDGATLILSKVGVSQQP-------------------EDSQQDLPGERHA 1580
Query: 1617 MITPDQETGTKLWHLVKNHDHADHREGDRGS-------KMVSEIYLTRLLATKGTLQKFV 1669
++ E ++WHLV+ D D + RGS K ++EIYLTRLL+ KGTLQ+FV
Sbjct: 1581 LL----EEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQFV 1636
Query: 1670 DDLFETVFSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVI 1729
D+ F++V + H A+P A+KY FDFLDEQA++ I D D H WK+N LPLRFWVN++
Sbjct: 1637 DNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNIL 1693
Query: 1730 KNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVE 1789
KNP F+FD+H + + DA LSV+AQTFMD+C+ +EH+L +DSPSNKLLYAK+I YK VE
Sbjct: 1694 KNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVE 1753
Query: 1790 RYYRDIAKMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDA 1849
YY+ I +M +SDQDM+ +L E SR H + L AL++LY Y KY EI+ AL+ D
Sbjct: 1754 DYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDP 1813
Query: 1850 SCRKHKLRQKLEQIISLVSS 1869
+ +K +L +L+QI + + +
Sbjct: 1814 AAQKMQLAFRLQQIAAALEN 1833
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 860 bits (2223), Expect = 0.0
Identities = 637/1994 (31%), Positives = 970/1994 (48%), Gaps = 240/1994 (12%)
Query: 6 LLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRA 65
LLLLL A GAL + R F + T + A+ G V++ AVNR+++L+ L A
Sbjct: 35 LLLLLGAARAGALEIQ--RRFP-SPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEA 91
Query: 66 HVT-GPVEDNARCYPPPSMRV-CAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFL 123
GPV D+ C+ P + C H DN NK+L +D +V CGSI+QG CQ
Sbjct: 92 EAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLR 151
Query: 124 RLDDLFKLG----------EPHHRKEHYLS-GAQEPD-SMAGVIVEQ--GQGPSKLFVGT 169
R ++ + EP L+ A P+ S G+++ G G S+L VG
Sbjct: 152 RRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLVGA 211
Query: 170 AVDGKSEYF---------------PTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214
G F P ++ R L + D A +F+ PSD
Sbjct: 212 TYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLN----------PSD 261
Query: 215 T--LSLYPAFDIYYIYGFVSA------------SFVYFLTLQLDTQQTLLDTAGEKFFTS 260
L + + GFVSA S+ Y L L+++ D + S
Sbjct: 262 DNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAY---LALNSEARAGDKESQA--RS 316
Query: 261 KIVRMC-----AGDSEFY--SYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPAD 313
+ R+C GD++ SY++ + C A A G L ++ + V
Sbjct: 317 LLARICLPHGAGGDAKKLTESYIQLGLQC------------AGGAGRGDLYSRLVSVFPA 364
Query: 314 EDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCY---RGEGTLALPWLLN 370
+ LF +F + Q + A+ LC F +++ A IR +C+ + L ++
Sbjct: 365 RERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQ 424
Query: 371 KELPC----INTPMQINGNFCGLV-LNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQH 425
P +N +Q CG L PL L ++ P+ G+ SVA + +
Sbjct: 425 GTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFR--APGLTSVAVASVNNY 482
Query: 426 SVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSP-DHRHIYLLSEKQVS 484
+ VF+GT +G L K+ ++ V V G P+ + F P D ++YL++ Q++
Sbjct: 483 TAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMA 542
Query: 485 QLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPH---GFAEELSKCVQ 541
++ V C + +C C+G+ D +CGWC L RC + C +S H +E S+C
Sbjct: 543 RVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPA 602
Query: 542 VRVRPNNVSVTS--PGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSL 599
+ V P+ + V PG+ L ++ ++P LS G+ A + V G +
Sbjct: 603 MTVLPSEIDVRQEYPGMILQIS-GSLPSLS-GMEMACDYGNNIRTVARVPGPAF--GHQI 658
Query: 600 QELRALTRGHGATRTVRLQLLSKETGVRFAG-----ADFVFYNCSVL------QSCMSCV 648
L R ++ E VR G A+F Y+CS +C SC+
Sbjct: 659 AYCNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCL 718
Query: 649 GSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKN 708
+ +PC WC +H+C S C SP+ CP L S +P G Q + + N
Sbjct: 719 SAQWPCFWCSQQHSCVSNQSRCEASPNPT-SPQDCPRTLLSPLAPVPTGGSQNILVPLAN 777
Query: 709 LPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWD 768
Q EC G ++ AV N S V+C + + L +
Sbjct: 778 TAFFQGAA--LECSF---GLEEIFEAVWVNESVVRCDQV-VLHTTRKSQVFPLSLQLKGR 831
Query: 769 GDFPIDKPPSFRALLYKCWAQRPSCGLCL-KADPRFNCGWCISEHRCQLRTHCPAPKTNW 827
+D P ++Y C P C CL + D C W C+LR
Sbjct: 832 PARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGHLCMW---SDGCRLRG--------- 879
Query: 828 MHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLGLLSREV--GLRVAGVRCNSIP 885
L C P I I PL GP +GGT +TI G NLG +V G+ + GV C +P
Sbjct: 880 -PLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLP 938
Query: 886 AEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRG 945
Y +E IVC V P PGP+ V +A +S +S+V P + P+ G
Sbjct: 939 DRYTVSEEIVC------VTGPAPGPLSGVV-TVNASKEGKSRDRFSYVLPLVHSLEPTMG 991
Query: 946 PASGGTRLTISGSSLDAGSRVTVTVRDSE-CQFVRRDAKAIVCISPLSTLGPSQAPITLA 1004
P +GGTR+TI G+ L GS + V V D++ C + R +I C P L P+ P+ +
Sbjct: 992 PKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIACTMPEGAL-PAPVPVCVR 1050
Query: 1005 IDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIE 1064
+R L + Y Q+P +T + P S ++G ITV+G VQ + + G E
Sbjct: 1051 FERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGRE 1110
Query: 1065 TTNTCQVINDTAMLCKAPGIFLGRPQP-------RAQGEHPDEFGFLLDHVQTARSLNRS 1117
T C+V+N T + C +PG P RA + LLD + R +R
Sbjct: 1111 PT-LCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRG-SRF 1168
Query: 1118 SFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVS 1177
Y P+P F + PG + L + + G Y V IG C + +
Sbjct: 1169 RLDYLPNPQFSTAKREKWIKHHPGEPLTLV-IHKEQDSLGLQSHEYRVKIGQVSCDIQIV 1227
Query: 1178 DTQLLCDSPSQT-----GRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGLLL 1232
+++ S +++ G+ P+ + VG + TL + + +++ + LLL
Sbjct: 1228 SDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQLGGSETAIIVSIVICSV---LLL 1284
Query: 1233 LAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINELTNHMDEV 1292
L++ A+ V + K++ A+R ++ LQM+ +ES++ E ++ FAELQTD+ +LT ++
Sbjct: 1285 LSVVALFV-FCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRS 1343
Query: 1293 Q-IPFLDYRTYAVRVLFP------------------------GIEAHPVLKELDTP---- 1323
Q IPFL+Y+ + R FP E HP+L E P
Sbjct: 1344 QGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCR 1403
Query: 1324 PNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLL 1383
PN+E+ + LF LL+++ F++ F+H LE Q F++RDR ++ASL +AL +L+Y T ++
Sbjct: 1404 PNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIM 1463
Query: 1384 KQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAI 1443
K+LL DLI+ + + +PKL+LRRTESV EKMLTNW + ++ L+E GEP FLL CAI
Sbjct: 1464 KELLVDLIDAS--AAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAI 1521
Query: 1444 KQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSI 1503
KQQ+ KG IDAITG+ARY+L+E+ L+R+ I+ K L+ V + G + V+ ++ D++
Sbjct: 1522 KQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLN-VSFQGCGMDSLSVRAMDTDTL 1580
Query: 1504 TQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLA 1563
TQ K+K+L+ K +PYSQ P+AED+DLEW IL+D D T+ +E K+LN+LA
Sbjct: 1581 TQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLA 1640
Query: 1564 HYQVTDGSLVA--LVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPD 1621
HY++ +G+ +A L+ K+ +L R + L D
Sbjct: 1641 HYKIPEGASLAMSLIDKK------------DNTLGRVKDL-------------------D 1669
Query: 1622 QETGTKLWHLVKNHDH-----ADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETV 1676
E K +HLV D HR+ R K++ EIYLTRLL+TKGTLQKF+DDLF+ +
Sbjct: 1670 TE---KYFHLVLPTDELAEPKKSHRQSHR-KKVLPEIYLTRLLSTKGTLQKFLDDLFKAI 1725
Query: 1677 FSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVF 1736
S R PLA+KY FDFL+EQA++R ISDPD H WK+N LPLRFWVN++KNPQFVF
Sbjct: 1726 LSI--REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVF 1783
Query: 1737 DIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIA 1796
DI K DACLSV+AQ F+D+CS S+ +LGKDSP+NKLLYAK+IP Y+ V+RYY+ I
Sbjct: 1784 DIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQ 1843
Query: 1797 KMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKL 1856
M +S+Q+M+A+L E+SR + ++F+ A+ E+Y Y +YR +I+ AL+ + + R+ +L
Sbjct: 1844 DMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQL 1903
Query: 1857 RQKLEQIISLVSSD 1870
+ K EQ+++L+ +
Sbjct: 1904 QHKFEQVVALMEDN 1917
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 751 bits (1940), Expect = 0.0
Identities = 475/1263 (37%), Positives = 690/1263 (54%), Gaps = 136/1263 (10%)
Query: 690 GDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPA------VRFNSSSVQ 743
G L+PV V + + L +NL Q G + ECV+ ++G + V A V
Sbjct: 921 GSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVT 980
Query: 744 CQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRF 803
CQ SYE + + + + G +D +LY C C C A P++
Sbjct: 981 CQQHQLSYEALQP-ELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQY 1039
Query: 804 NCGWCISEH-RCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVG 862
C WC E RC R C + T+C P I + PL GP +GGTRVTI G
Sbjct: 1040 GCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDGGTRVTIRG 1092
Query: 863 DNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSA 920
NLG ++V + VAGV C EY + +VC S VE+
Sbjct: 1093 SNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEV-----PG 1147
Query: 921 DFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAG--SRVTVTVRDSECQFV 978
R SE +++ P + P+RGP +GGTRLT++GS L G + V V D C +
Sbjct: 1148 RGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLL 1207
Query: 979 -RRDAKAIVC-ISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIIN 1036
+ ++ + C SP T P+ P+ + + YT DP +T PT S ++
Sbjct: 1208 PEQQSEQLRCETSPRPT--PATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLS 1265
Query: 1037 GSTAITVSGTHLLTVQEPRVRA---------------KYRGIETT--------------N 1067
G I V G +L VQ PR+R + R + T
Sbjct: 1266 GGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEE 1325
Query: 1068 TCQVINDTAMLCKAPGIFLGRPQ-PRAQGEHPDEFGFLLDH-VQTARSLNRSSFTYYPDP 1125
C V + + C+ P + G P+ P + E F+LD+ V +LN + F+Y DP
Sbjct: 1326 PCHVNSSQLITCRTPAL-PGLPEDPWVRVE------FILDNLVFDFATLNPTPFSYEADP 1378
Query: 1126 SFEPLGPSGV---LDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL-TVSDTQL 1181
+ +PL P KPGS ++G+NL A S+ +IG PC + T++ L
Sbjct: 1379 TLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAM---SKEEVVAMIGDGPCVVKTLTRHHL 1435
Query: 1182 LCDSPSQTGRQPV----------------MVLVGGLEFWLGTLHISAER--ALTLPAMMG 1223
C+ P + QP+ V +G L F LG + E A + A +G
Sbjct: 1436 YCEPPVE---QPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVG 1492
Query: 1224 LAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIN 1283
L G LL L + +++ Y+RK++ A R K++Q+Q++NLES V CK+ F +L T++
Sbjct: 1493 LGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMT 1552
Query: 1284 ELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP----PNVEKALRLFGQLLHS 1339
+LT+ + IPFLDY+ YA R+ FPG P+ ++L P P VE+ L LL+S
Sbjct: 1553 DLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNS 1612
Query: 1340 RAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKN 1399
+ F+ FIHTLE+Q +FS RDR VASL VAL +L+Y T +L+ LL+DL+ + + +KN
Sbjct: 1613 KLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN 1671
Query: 1400 HPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEA 1459
PKL+LRRTE+V EK+LTNW + L+ F+++ GEPL++L+ IK Q++KGP+D++TG+A
Sbjct: 1672 -PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKA 1730
Query: 1460 RYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQ---VPVKVLNCDSITQAKDKLLDTVYK 1516
+Y+L++++L+R+ ++Y+ LTL+ + G+ + VPVKVL+CD+I+QAK+K+LD +YK
Sbjct: 1731 KYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYK 1790
Query: 1517 GIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALV 1576
G+P +QRP +D+EWR G +IL DEDVT++++ W+RLN+L HY+V DG+ VALV
Sbjct: 1791 GVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALV 1850
Query: 1577 PKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSL-RSRAPMITPDQETGTKLWHLVKNH 1635
P T+ + R + D + R PM+ E G + WHLVK
Sbjct: 1851 P------------CLTKHVLR--------ENQDYVPGERTPMLEDVDEGGIRPWHLVKPS 1890
Query: 1636 DHADHREGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSAL 1686
D + RGS K + EIYLTRLL+ KGTLQKFVDDLF+ + ST+ +
Sbjct: 1891 DEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PV 1947
Query: 1687 PLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDA 1746
PLA+KY FD LDEQA Q ISD D H WK+N LPLRFW+N+IKNPQFVFD+ + DA
Sbjct: 1948 PLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDA 2007
Query: 1747 CLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDM 1806
L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK VERYY DI + SDQ+M
Sbjct: 2008 VLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEM 2067
Query: 1807 DAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISL 1866
++ L E S ++ D AL+ELY Y+ KY +I+TAL+ D + +K +L +L+QI +
Sbjct: 2068 NSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAA 2127
Query: 1867 VSS 1869
V +
Sbjct: 2128 VEN 2130
Score = 249 bits (635), Expect = 2e-65
Identities = 209/723 (28%), Positives = 320/723 (44%), Gaps = 76/723 (10%)
Query: 1 MPSVCLLLLLFLAVGGALGNRPF--RAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAP 58
MP++ LL L G L +P AF T L HLA +G +++GA N +F+L+P
Sbjct: 1 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
Query: 59 NLTELRAHV-TGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQ 117
L +L A V TGPV D+ C PP C + P +N N+LLL+ A LV CGS+ Q
Sbjct: 61 GL-QLEATVSTGPVLDSRDCLPPVMPDECP-QAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
Query: 118 GICQFLRLDDLFKLG-EPHHRKEHYLSGAQEPD-SMAGVIVEQGQGPSKLFVGTAVD--G 173
G+C+ RL L +L P + A +P S G++ + G LFVG G
Sbjct: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
Query: 174 KSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSA 233
P +++R L + A + Y++ K+ LS Y +++ F
Sbjct: 177 VGGGIPPITTRALWPPDPQA---AFSYEET-----AKLAVGRLSEYSH---HFVSAFARG 225
Query: 234 SFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQ 293
+ YFL L+ D Q A + F + + R+C D +YSYVE P+ C G Y L+Q
Sbjct: 226 ASAYFLFLRRDLQ------AQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQ 277
Query: 294 SAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ--------TILCLFTLSNI 345
+A +A + A +VLF FS P + LC F L +
Sbjct: 278 AAAVATSREV--------AHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEV 329
Query: 346 NAHIRRRIQSCYRGEGTLA-------LPWLLNKELPCINTPMQ-INGNFCGLVLN-QPLG 396
+ R +CY EG + + +N + C P+ ++ CG P+
Sbjct: 330 DRLANRTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMA 387
Query: 397 GLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPV 456
+E P+L + +VA H++ F+G G L +V + D H Y T +
Sbjct: 388 SRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI 447
Query: 457 VDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHR 516
GS + RDL F H+Y++++ + ++PV +C Q+ CA+CL DP+CGWCVL R
Sbjct: 448 QQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGR 507
Query: 517 CCREGACLGASAPH----GFAEELSKCVQV-RVRPNNVSVTSPGVQLTVTLHNVPDLSAG 571
C R C P F EL C+QV + P N+S ++ +++ ++P L G
Sbjct: 508 CSRRSECSRGQGPEQWLWSFQPELG-CLQVAAMSPANIS-REETREVFLSVPDLPPLWPG 565
Query: 572 VSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGA 631
S + LL ++CPSP E L RG V + + + V A
Sbjct: 566 ESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRG---ADYVSVSVELRFGAVVIAKT 622
Query: 632 DFVFYNCSVL------QSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPE 685
FY+C + C +CV S + C+WC ++H CT H+ S G + + P
Sbjct: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCT---HKASCDAGPMVASHQSPL 679
Query: 686 ILP 688
+ P
Sbjct: 680 VSP 682
Score = 42.0 bits (97), Expect = 0.006
Identities = 74/293 (25%), Positives = 115/293 (39%), Gaps = 49/293 (16%)
Query: 554 PGVQLTVTLHNVPDLSAGVSCAF--EAAAENEAVLLPSGELLCP--SPSLQELRALTRGH 609
PG+QLT + D G + AF ++ + V L G P + S+Q+ A++R
Sbjct: 401 PGIQLTAVAVTMED---GHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDL 457
Query: 610 GATRTVR-LQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYP-CHWCKYRHTCTSRP 667
T L ++++ T ++ A +C+ C SC+ P C WC C SR
Sbjct: 458 TFDGTFEHLYVMTQSTLLKVPVA-----SCAQHLDCASCLAHRDPYCGWCVLLGRC-SRR 511
Query: 668 HECSFQEGRVH-----SPE-GCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYEC 721
ECS +G PE GC ++ I + + L +LP G+ +Y C
Sbjct: 512 SECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPGE-SYSC 570
Query: 722 VVRVQGRQQRVPAVRFNSSSVQCQNASYSY-----EGDEHGDT--ELDFSVVWDGDFPID 774
+ + PA+ S V C + S G ++ EL F V +
Sbjct: 571 ----HFGEHQSPAL-LTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLS 625
Query: 775 KPPSFRALLYKCWAQ---RPS--CGLCLKADPRFNCGWCISEHRCQLRTHCPA 822
Y C A RPS C C+ + R+ C WC+ +H C + C A
Sbjct: 626 --------FYDCVAVTELRPSAQCQACVSS--RWGCNWCVWQHLCTHKASCDA 668
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 751 bits (1940), Expect = 0.0
Identities = 475/1263 (37%), Positives = 690/1263 (54%), Gaps = 136/1263 (10%)
Query: 690 GDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPA------VRFNSSSVQ 743
G L+PV V + + L +NL Q G + ECV+ ++G + V A V
Sbjct: 921 GSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVT 980
Query: 744 CQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRF 803
CQ SYE + + + + G +D +LY C C C A P++
Sbjct: 981 CQQHQLSYEALQP-ELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQY 1039
Query: 804 NCGWCISEH-RCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVG 862
C WC E RC R C + T+C P I + PL GP +GGTRVTI G
Sbjct: 1040 GCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDGGTRVTIRG 1092
Query: 863 DNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSA 920
NLG ++V + VAGV C EY + +VC S VE+
Sbjct: 1093 SNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEV-----PG 1147
Query: 921 DFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAG--SRVTVTVRDSECQFV 978
R SE +++ P + P+RGP +GGTRLT++GS L G + V V D C +
Sbjct: 1148 RGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLL 1207
Query: 979 -RRDAKAIVC-ISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIIN 1036
+ ++ + C SP T P+ P+ + + YT DP +T PT S ++
Sbjct: 1208 PEQQSEQLRCETSPRPT--PATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLS 1265
Query: 1037 GSTAITVSGTHLLTVQEPRVRA---------------KYRGIETT--------------N 1067
G I V G +L VQ PR+R + R + T
Sbjct: 1266 GGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEE 1325
Query: 1068 TCQVINDTAMLCKAPGIFLGRPQ-PRAQGEHPDEFGFLLDH-VQTARSLNRSSFTYYPDP 1125
C V + + C+ P + G P+ P + E F+LD+ V +LN + F+Y DP
Sbjct: 1326 PCHVNSSQLITCRTPAL-PGLPEDPWVRVE------FILDNLVFDFATLNPTPFSYEADP 1378
Query: 1126 SFEPLGPSGV---LDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL-TVSDTQL 1181
+ +PL P KPGS ++G+NL A S+ +IG PC + T++ L
Sbjct: 1379 TLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAM---SKEEVVAMIGDGPCVVKTLTRHHL 1435
Query: 1182 LCDSPSQTGRQPV----------------MVLVGGLEFWLGTLHISAER--ALTLPAMMG 1223
C+ P + QP+ V +G L F LG + E A + A +G
Sbjct: 1436 YCEPPVE---QPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVG 1492
Query: 1224 LAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIN 1283
L G LL L + +++ Y+RK++ A R K++Q+Q++NLES V CK+ F +L T++
Sbjct: 1493 LGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMT 1552
Query: 1284 ELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP----PNVEKALRLFGQLLHS 1339
+LT+ + IPFLDY+ YA R+ FPG P+ ++L P P VE+ L LL+S
Sbjct: 1553 DLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNS 1612
Query: 1340 RAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKN 1399
+ F+ FIHTLE+Q +FS RDR VASL VAL +L+Y T +L+ LL+DL+ + + +KN
Sbjct: 1613 KLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN 1671
Query: 1400 HPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEA 1459
PKL+LRRTE+V EK+LTNW + L+ F+++ GEPL++L+ IK Q++KGP+D++TG+A
Sbjct: 1672 -PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKA 1730
Query: 1460 RYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQ---VPVKVLNCDSITQAKDKLLDTVYK 1516
+Y+L++++L+R+ ++Y+ LTL+ + G+ + VPVKVL+CD+I+QAK+K+LD +YK
Sbjct: 1731 KYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYK 1790
Query: 1517 GIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALV 1576
G+P +QRP +D+EWR G +IL DEDVT++++ W+RLN+L HY+V DG+ VALV
Sbjct: 1791 GVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALV 1850
Query: 1577 PKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSL-RSRAPMITPDQETGTKLWHLVKNH 1635
P T+ + R + D + R PM+ E G + WHLVK
Sbjct: 1851 P------------CLTKHVLR--------ENQDYVPGERTPMLEDVDEGGIRPWHLVKPS 1890
Query: 1636 DHADHREGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSAL 1686
D + RGS K + EIYLTRLL+ KGTLQKFVDDLF+ + ST+ +
Sbjct: 1891 DEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PV 1947
Query: 1687 PLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDA 1746
PLA+KY FD LDEQA Q ISD D H WK+N LPLRFW+N+IKNPQFVFD+ + DA
Sbjct: 1948 PLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDA 2007
Query: 1747 CLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDM 1806
L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK VERYY DI + SDQ+M
Sbjct: 2008 VLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEM 2067
Query: 1807 DAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISL 1866
++ L E S ++ D AL+ELY Y+ KY +I+TAL+ D + +K +L +L+QI +
Sbjct: 2068 NSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAA 2127
Query: 1867 VSS 1869
V +
Sbjct: 2128 VEN 2130
Score = 249 bits (635), Expect = 2e-65
Identities = 209/723 (28%), Positives = 320/723 (44%), Gaps = 76/723 (10%)
Query: 1 MPSVCLLLLLFLAVGGALGNRPF--RAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAP 58
MP++ LL L G L +P AF T L HLA +G +++GA N +F+L+P
Sbjct: 1 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
Query: 59 NLTELRAHV-TGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQ 117
L +L A V TGPV D+ C PP C + P +N N+LLL+ A LV CGS+ Q
Sbjct: 61 GL-QLEATVSTGPVLDSRDCLPPVMPDECP-QAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
Query: 118 GICQFLRLDDLFKLG-EPHHRKEHYLSGAQEPD-SMAGVIVEQGQGPSKLFVGTAVD--G 173
G+C+ RL L +L P + A +P S G++ + G LFVG G
Sbjct: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
Query: 174 KSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSA 233
P +++R L + A + Y++ K+ LS Y +++ F
Sbjct: 177 VGGGIPPITTRALWPPDPQA---AFSYEET-----AKLAVGRLSEYSH---HFVSAFARG 225
Query: 234 SFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQ 293
+ YFL L+ D Q A + F + + R+C D +YSYVE P+ C G Y L+Q
Sbjct: 226 ASAYFLFLRRDLQ------AQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQ 277
Query: 294 SAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ--------TILCLFTLSNI 345
+A +A + A +VLF FS P + LC F L +
Sbjct: 278 AAAVATSREV--------AHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEV 329
Query: 346 NAHIRRRIQSCYRGEGTLA-------LPWLLNKELPCINTPMQ-INGNFCGLVLN-QPLG 396
+ R +CY EG + + +N + C P+ ++ CG P+
Sbjct: 330 DRLANRTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMA 387
Query: 397 GLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPV 456
+E P+L + +VA H++ F+G G L +V + D H Y T +
Sbjct: 388 SRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI 447
Query: 457 VDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHR 516
GS + RDL F H+Y++++ + ++PV +C Q+ CA+CL DP+CGWCVL R
Sbjct: 448 QQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGR 507
Query: 517 CCREGACLGASAPH----GFAEELSKCVQV-RVRPNNVSVTSPGVQLTVTLHNVPDLSAG 571
C R C P F EL C+QV + P N+S ++ +++ ++P L G
Sbjct: 508 CSRRSECSRGQGPEQWLWSFQPELG-CLQVAAMSPANIS-REETREVFLSVPDLPPLWPG 565
Query: 572 VSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGA 631
S + LL ++CPSP E L RG V + + + V A
Sbjct: 566 ESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRG---ADYVSVSVELRFGAVVIAKT 622
Query: 632 DFVFYNCSVL------QSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPE 685
FY+C + C +CV S + C+WC ++H CT H+ S G + + P
Sbjct: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCT---HKASCDAGPMVASHQSPL 679
Query: 686 ILP 688
+ P
Sbjct: 680 VSP 682
Score = 42.0 bits (97), Expect = 0.006
Identities = 74/293 (25%), Positives = 115/293 (39%), Gaps = 49/293 (16%)
Query: 554 PGVQLTVTLHNVPDLSAGVSCAF--EAAAENEAVLLPSGELLCP--SPSLQELRALTRGH 609
PG+QLT + D G + AF ++ + V L G P + S+Q+ A++R
Sbjct: 401 PGIQLTAVAVTMED---GHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDL 457
Query: 610 GATRTVR-LQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYP-CHWCKYRHTCTSRP 667
T L ++++ T ++ A +C+ C SC+ P C WC C SR
Sbjct: 458 TFDGTFEHLYVMTQSTLLKVPVA-----SCAQHLDCASCLAHRDPYCGWCVLLGRC-SRR 511
Query: 668 HECSFQEGRVH-----SPE-GCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYEC 721
ECS +G PE GC ++ I + + L +LP G+ +Y C
Sbjct: 512 SECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPGE-SYSC 570
Query: 722 VVRVQGRQQRVPAVRFNSSSVQCQNASYSY-----EGDEHGDT--ELDFSVVWDGDFPID 774
+ + PA+ S V C + S G ++ EL F V +
Sbjct: 571 ----HFGEHQSPAL-LTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLS 625
Query: 775 KPPSFRALLYKCWAQ---RPS--CGLCLKADPRFNCGWCISEHRCQLRTHCPA 822
Y C A RPS C C+ + R+ C WC+ +H C + C A
Sbjct: 626 --------FYDCVAVTELRPSAQCQACVSS--RWGCNWCVWQHLCTHKASCDA 668
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 462 bits (1190), Expect = e-129
Identities = 224/435 (51%), Positives = 299/435 (68%)
Query: 35 HLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVD 94
HL V TG +++GAVNR++KL+ +L L H TGP EDN +CYPP ++ C L +
Sbjct: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
Query: 95 NINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGV 154
N+NK+LLIDY RL+ACGS++QGIC+ LRL+DLFKLGEP+H+KEHYLSG E S+ GV
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGV 172
Query: 155 IVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214
IV KLF+ TAVDGK EYFPT+SSRKL + ++ MF+ V+ DEFV+S IKIPSD
Sbjct: 173 IVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSD 232
Query: 215 TLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYS 274
T ++ P FDIYY+YGF S +FVYFLTLQ + T E+ +TSK+VR+C D+ F S
Sbjct: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNS 292
Query: 275 YVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ 334
YVE PIGC GVEYRL+Q+A+L+K G +L + LGV D+D+LFT+FS+GQK + +
Sbjct: 293 YVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDE 352
Query: 335 TILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQP 394
+ LC+F L IN I+ R+QSCYRGEGTL L WL K++PC + + I+ NFCGL +N P
Sbjct: 353 SALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAP 412
Query: 395 LGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETV 454
LG ++ G+P+ + D M SV AY Y+ HS+ F+GT+SG LKK+ +T
Sbjct: 413 LGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKMPGTSLCPTLELQTG 472
Query: 455 PVVDGSPILRDLLFS 469
P + + +LLFS
Sbjct: 473 PRSHRATVTLELLFS 487
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 461 bits (1186), Expect = e-129
Identities = 224/427 (52%), Positives = 296/427 (69%), Gaps = 1/427 (0%)
Query: 35 HLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVD 94
HL V TG +++GAVNR++KL+ +L L H TGP EDN +CYPP ++ C L +
Sbjct: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
Query: 95 NINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGV 154
N+NK+LLIDY RL+ACGS++QGIC+ LRL+DLFKLGEP+H+KEHYLSG E S+ GV
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGV 172
Query: 155 IVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214
IV KLF+ TAVDGK EYFPT+SSRKL + ++ MF+ V+ DEFV+S IKIPSD
Sbjct: 173 IVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSD 232
Query: 215 TLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYS 274
T ++ P FDIYY+YGF S +FVYFLTLQ + T E+ +TSK+VR+C D+ F S
Sbjct: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNS 292
Query: 275 YVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ 334
YVE PIGC GVEYRL+Q+A+L+K G +L + LGV D+D+LFT+FS+GQK + +
Sbjct: 293 YVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDE 352
Query: 335 TILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQP 394
+ LC+F L IN I+ R+QSCYRGEGTL L WL K++PC + + I+ NFCGL +N P
Sbjct: 353 SALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAP 412
Query: 395 LGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETV 454
LG ++ G+P+ + D M SV AY Y+ HS+ F+GT+SG LKK G Q E +
Sbjct: 413 LGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWI 472
Query: 455 PVVDGSP 461
V+G P
Sbjct: 473 G-VEGDP 478
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 404 bits (1038), Expect = e-112
Identities = 246/656 (37%), Positives = 375/656 (57%), Gaps = 54/656 (8%)
Query: 1205 LGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLE 1264
LG L + E+ L LL++ I A + + K+++ R + Q++ LE
Sbjct: 929 LGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQ---QLELLE 985
Query: 1265 SRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFP--GIEAHPVLKELDT 1322
S + E ++ FAELQ D ++ + V PFLDY+ +A+R FP G H +++
Sbjct: 986 SELRKEIRDGFAELQMDKLDVVDSFGTV--PFLDYKHFALRTFFPESGGFTHIFTEDMHN 1043
Query: 1323 PPNVEK--ALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYAT 1380
+K +L L+ +++F++T IHTLE Q +FS++DR AS +ALQ++L Y T
Sbjct: 1044 RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLT 1103
Query: 1381 GLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLY 1440
+L+ L DL+E+ S PKL+LRRTESV EK+LTNW + L FL+E GEP +LL
Sbjct: 1104 SILEVLTRDLMEQC--SNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLV 1161
Query: 1441 CAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCV---CPENEGS---AQVP 1494
+ Q++ KGP+D IT +A Y+L+ED L+ Q ++ T+ L+ V PENE + +
Sbjct: 1162 TTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNIS 1221
Query: 1495 VKVLNCDSITQAKDKLLDTVYK--GIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKI 1552
V VL+CD+I QAK+K+ G PY + ++ LE + G + +L + + +
Sbjct: 1222 VNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQ--LNEIGLELQMGTRQKELLDIDSSSVIL 1279
Query: 1553 ECDWKRLNSLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLR 1612
E +LN++ HY++++GS + + K +AN FT + +
Sbjct: 1280 EDGITKLNTIGHYEISNGSTIKVFKK------IAN---FTSDVEYSDD------------ 1318
Query: 1613 SRAPMITPDQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDL 1672
+I PD E D R + V E+YLT+LL+TK + ++ L
Sbjct: 1319 -HCHLILPDSEAF---------QDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKL 1368
Query: 1673 FETVFSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNP 1732
F +++S + S P AIKY FDFLD QA+ ++I+DPDV H WK+N LPLRFWVN++KNP
Sbjct: 1369 FRSIWSLPN--SRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNP 1426
Query: 1733 QFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYY 1792
QFVFDI K D CLSV+AQ FMD+ S +E +LGK++P+NKLLYAKDIP YK V+ YY
Sbjct: 1427 QFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYY 1486
Query: 1793 RDIAKMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRD 1848
+ I + +S +M+ +L ++S+ H ++F+ AL E+Y Y+ KY EIL L+R+
Sbjct: 1487 KAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERE 1542
Score = 82.4 bits (202), Expect = 4e-15
Identities = 91/383 (23%), Positives = 152/383 (39%), Gaps = 64/383 (16%)
Query: 315 DVLFTIFS----QGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPW-LL 369
DV +FS +GQ+ R+ P T LCLF +S I A +R + W
Sbjct: 304 DVWAGVFSAAAGEGQERRS--PTTTALCLFRMSEIQARAKR-------------VSWDFK 348
Query: 370 NKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADST---DGMASVAAYTYRQHS 426
E C +QP E + +A ST + SV +
Sbjct: 349 TAESHCKEG-------------DQP-------ERVQPIASSTLIHSDLTSVYGTVVMNRT 388
Query: 427 VVFIGTRSGSLKKVRVDGFQDAHLYETV-PVVDGSPILRDLLFSP-DHRHIYLLSEKQVS 484
V+F+GT G L KV + ++ E + + + +P+ L+ P + +IYL + K+V
Sbjct: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVR 448
Query: 485 QLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELS---KCVQ 541
++ V C +++SC+ CL + DPHCGWC RC +G C+ + + + S KC +
Sbjct: 449 RIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPK 508
Query: 542 VRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQE 601
+++ ++ T+ + + + + + V + E P+ C P+
Sbjct: 509 IQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELCQNKSQ---PNRTCTCSIPT--- 562
Query: 602 LRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYRH 661
+ V + + G F F NCS L+ C +CV + C WCK
Sbjct: 563 -------RATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPACVET--GCAWCKSAR 613
Query: 662 TCTSRPHECSFQEGRVHSPEGCP 684
C P + E CP
Sbjct: 614 RCI-HPFTACDPSDYERNQEQCP 635
Score = 39.3 bits (90), Expect = 0.036
Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 11/74 (14%)
Query: 792 SCGLCLKA-DPRFNCGWCISEHRCQLRTHCPAPKT--NWMHLSQKGTRCSHPRITQIHPL 848
SC CL A DP +CGWC S RC + C + NW+ +S +C P+I +
Sbjct: 460 SCSECLTATDP--HCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKC--PKI----QI 511
Query: 849 VGPKEGGTRVTIVG 862
+ + T VT+VG
Sbjct: 512 IRSSKEKTTVTMVG 525
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 129 bits (325), Expect = 2e-29
Identities = 136/578 (23%), Positives = 265/578 (45%), Gaps = 90/578 (15%)
Query: 30 DTTLTHLAVHRVTGEVFVGAVNRVFKL-APNLTELRAHVTGPVEDNARCYPPPSMRVCAH 88
+T + ++ +H +F+GA N ++ L +L ++ + TGPV ++ C+P A+
Sbjct: 49 ETPIQNVILHE--HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKAN 106
Query: 89 RLAPV--DNINKLLLID-YAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSG- 144
V DNIN L++D Y +L++CGS+ +G CQ + PH+ S
Sbjct: 107 LSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQ--------RHVFPHNHTADIQSEV 158
Query: 145 -----------AQEPDSMAGVIVEQGQGPSK-----LFVGTAVDGKSEYFP-----TLSS 183
+Q PD + + + K FVG ++ S YFP ++S
Sbjct: 159 HCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTIN--SSYFPDHPLHSISV 216
Query: 184 RKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQL 243
R+L +++ D F + ++ + + YP I Y++ F S +F+YFLT+Q
Sbjct: 217 RRL---KETKDGFMFLTDQSYID----VLPEFRDSYP---IKYVHAFESNNFIYFLTVQR 266
Query: 244 DTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGC---------SWRGVEYRLVQS 294
+T LD + F ++I+R C+ +S +SY+E P+ C S + + ++Q+
Sbjct: 267 ET----LDA---QTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQA 319
Query: 295 AHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQ 354
A+++KPG LA+ +G ++D+LF +F+Q + + A P ++ +C F + +N + +
Sbjct: 320 AYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVN 379
Query: 355 SCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQ-PLGGLHVIEGLPLLAD--ST 411
L + N E C N + N + C ++ ++ + L S
Sbjct: 380 K--NNVRCLQHFYGPNHE-HCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSE 436
Query: 412 DGMASVAAYTYRQHSVVFIGTRSGSLKKVRV--DGFQDAHLYETVPVVDGSPILRDLLFS 469
+ S++ + ++ +GT G +V V G H+ ++D P+ +++
Sbjct: 437 VLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNF---LLDSHPVSPEVIVE 493
Query: 470 ---PDHRHIYLLSEKQVSQLPVE--TCEQYQSCAACLGSGDP--HCGWCVLRHRCCREGA 522
+ + +++ K+++++P+ C +QSC+ CL S P CGWC +C R
Sbjct: 494 HTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCL-SAPPFVQCGWC--HDKCVRSEE 550
Query: 523 CLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTV 560
CL + + +++ +V PN+ + G +LT+
Sbjct: 551 CLSGT----WTQQICLPAIYKVFPNSAPLEG-GTRLTI 583
Score = 107 bits (267), Expect = 1e-22
Identities = 99/401 (24%), Positives = 170/401 (42%), Gaps = 32/401 (7%)
Query: 792 SCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGP 851
SC CL A P CGWC +C C + W + P I ++ P P
Sbjct: 525 SCSQCLSAPPFVQCGWC--HDKCVRSEECLSG--TWTQ------QICLPAIYKVFPNSAP 574
Query: 852 KEGGTRVTIVGDNLGLL-SREVGLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGP 910
EGGTR+TI G + G + + L+ V + +E + ++ ++ P+
Sbjct: 575 LEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHF 634
Query: 911 VELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTV 970
+ S T +S+V P +SP GP +GGT LT++G+ L++G+ +++
Sbjct: 635 NMSII--ISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISI 692
Query: 971 RDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEP 1030
C + C +P T+ ++ + L ID AN + I++Y +DP V + P
Sbjct: 693 GGKTCTLKSVSNSILECYTPAQTIS-TEFAVKLKIDLANRETS--IFSYREDPIVYEIHP 749
Query: 1031 TWSIINGSTAITVSGTHLLTVQEPR--VRAKYRGIETTNTCQ-VINDTAMLCKAPGIFLG 1087
T S I+G + IT G +L +V PR + G T CQ N + C P +
Sbjct: 750 TKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSL--- 806
Query: 1088 RPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLK 1147
Q Q + F+LD + + Y +P F+P ++ + + + +K
Sbjct: 807 -QQLNLQLPLKTKAFFMLDGILS----KYFDLIYVHNPVFKPFEKPVMISMGNENVLEIK 861
Query: 1148 GKNLIPAAAGSSRLNYTVLIGGQPC-SLTVSDTQLLCDSPS 1187
G ++ P A L +G + C ++ + +LC P+
Sbjct: 862 GNDIDPEAVKGEVLK----VGNKSCENIHLHSEAVLCTVPN 898
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 129 bits (325), Expect = 2e-29
Identities = 136/578 (23%), Positives = 265/578 (45%), Gaps = 90/578 (15%)
Query: 30 DTTLTHLAVHRVTGEVFVGAVNRVFKL-APNLTELRAHVTGPVEDNARCYPPPSMRVCAH 88
+T + ++ +H +F+GA N ++ L +L ++ + TGPV ++ C+P A+
Sbjct: 49 ETPIQNVILHE--HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKAN 106
Query: 89 RLAPV--DNINKLLLID-YAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSG- 144
V DNIN L++D Y +L++CGS+ +G CQ + PH+ S
Sbjct: 107 LSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQ--------RHVFPHNHTADIQSEV 158
Query: 145 -----------AQEPDSMAGVIVEQGQGPSK-----LFVGTAVDGKSEYFP-----TLSS 183
+Q PD + + + K FVG ++ S YFP ++S
Sbjct: 159 HCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTIN--SSYFPDHPLHSISV 216
Query: 184 RKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQL 243
R+L +++ D F + ++ + + YP I Y++ F S +F+YFLT+Q
Sbjct: 217 RRL---KETKDGFMFLTDQSYID----VLPEFRDSYP---IKYVHAFESNNFIYFLTVQR 266
Query: 244 DTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGC---------SWRGVEYRLVQS 294
+T LD + F ++I+R C+ +S +SY+E P+ C S + + ++Q+
Sbjct: 267 ET----LDA---QTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQA 319
Query: 295 AHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQ 354
A+++KPG LA+ +G ++D+LF +F+Q + + A P ++ +C F + +N + +
Sbjct: 320 AYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVN 379
Query: 355 SCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQ-PLGGLHVIEGLPLLAD--ST 411
L + N E C N + N + C ++ ++ + L S
Sbjct: 380 K--NNVRCLQHFYGPNHE-HCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSE 436
Query: 412 DGMASVAAYTYRQHSVVFIGTRSGSLKKVRV--DGFQDAHLYETVPVVDGSPILRDLLFS 469
+ S++ + ++ +GT G +V V G H+ ++D P+ +++
Sbjct: 437 VLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNF---LLDSHPVSPEVIVE 493
Query: 470 ---PDHRHIYLLSEKQVSQLPVE--TCEQYQSCAACLGSGDP--HCGWCVLRHRCCREGA 522
+ + +++ K+++++P+ C +QSC+ CL S P CGWC +C R
Sbjct: 494 HTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCL-SAPPFVQCGWC--HDKCVRSEE 550
Query: 523 CLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTV 560
CL + + +++ +V PN+ + G +LT+
Sbjct: 551 CLSGT----WTQQICLPAIYKVFPNSAPLEG-GTRLTI 583
Score = 96.3 bits (238), Expect = 3e-19
Identities = 99/419 (23%), Positives = 170/419 (40%), Gaps = 50/419 (11%)
Query: 792 SCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGP 851
SC CL A P CGWC +C C + W + P I ++ P P
Sbjct: 525 SCSQCLSAPPFVQCGWC--HDKCVRSEECLSG--TWTQ------QICLPAIYKVFPNSAP 574
Query: 852 KEGGTRVTIVGDNLGLL-SREVGLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGP 910
EGGTR+TI G + G + + L+ V + +E + ++ ++ P+
Sbjct: 575 LEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHF 634
Query: 911 VELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTV 970
+ S T +S+V P +SP GP +GGT LT++G+ L++G+ +++
Sbjct: 635 NMSII--ISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISI 692
Query: 971 RDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEP 1030
C + C +P T+ ++ + L ID AN + I++Y +DP V + P
Sbjct: 693 GGKTCTLKSVSNSILECYTPAQTIS-TEFAVKLKIDLANRETS--IFSYREDPIVYEIHP 749
Query: 1031 TWSII------------------NGSTAITVSGTHLLTVQEPR--VRAKYRGIETTNTCQ 1070
T S I +G + IT G +L +V PR + G T CQ
Sbjct: 750 TKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQ 809
Query: 1071 -VINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEP 1129
N + C P + Q Q + F+LD + + Y +P F+P
Sbjct: 810 HRSNSEIICCTTPSL----QQLNLQLPLKTKAFFMLDGILS----KYFDLIYVHNPVFKP 861
Query: 1130 LGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPC-SLTVSDTQLLCDSPS 1187
++ + + + +KG ++ P A L +G + C ++ + +LC P+
Sbjct: 862 FEKPVMISMGNENVLEIKGNDIDPEAVKGEVLK----VGNKSCENIHLHSEAVLCTVPN 916
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 117 bits (294), Expect = 8e-26
Identities = 127/482 (26%), Positives = 189/482 (39%), Gaps = 69/482 (14%)
Query: 792 SCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGP 851
+CG CL+A CGWC + C + CP S + C P++T+ HP GP
Sbjct: 532 TCGRCLRAWHFMGCGWC--GNMCGQQKECPG--------SWQQDHCP-PKLTEFHPHSGP 580
Query: 852 KEGGTRVTIVGDNLGLLSREVGLRVAGVR--------CNSIPAEYIS---------AERI 894
G TR+T+ G N L GL G C +P + E
Sbjct: 581 LRGSTRLTLCGSNFYL--HPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEF 638
Query: 895 VCEMEESLVPSPPPGPVELCVGDC--SADFRTQSEQV---YSFVTPTFDQVSPSRGPASG 949
CE+E + P V L V + FR V +SF+ P V P GP +G
Sbjct: 639 ECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAG 698
Query: 950 GTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRAN 1009
GT LT+ G SL G+ V V +EC R ++C +P G + A + L++
Sbjct: 699 GTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATP---PGATVASVPLSLQVGG 755
Query: 1010 ISSPG-LIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNT 1068
PG + Y +DP V + P IN + IT+ G HL + V + + G+ +
Sbjct: 756 AQVPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAWH-LVLSFHDGLRAVES 812
Query: 1069 -CQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSF 1127
C+ LC+ P + PQ G +AR + FT P F
Sbjct: 813 RCERQLPEQQLCRLPEYVVRDPQGWVAGN------------LSARGDGAAGFTL---PGF 857
Query: 1128 EPLGP-----SGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLL 1182
L P + ++ +KP H + + A A +N TV GG+ C ++
Sbjct: 858 RFLPPPHPPSANLVPLKPEEHAIKFEYIGLGAVADCVGINVTV--GGESCQHEFRGDMVV 915
Query: 1183 CDSPS--QTGRQ--PVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGLLLLAITAV 1238
C P Q G+ P+ V V G LG + + ++G+ LL+ A+
Sbjct: 916 CPLPPSLQLGQDGAPLQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATA 975
Query: 1239 LV 1240
LV
Sbjct: 976 LV 977
Score = 103 bits (258), Expect = 1e-21
Identities = 134/540 (24%), Positives = 221/540 (40%), Gaps = 106/540 (19%)
Query: 45 VFVGAVNRVFKLAPNLTELRAHVTGPVEDN-----ARCYPPPSMRVCAHRLAPVDNINKL 99
VFV NR+ L P+L +++ TGP D A C P P P D K+
Sbjct: 70 VFVAIRNRLHVLGPDLKSVQSLATGPAGDPGCQTCAACGPGPHG-------PPGDTDTKV 122
Query: 100 LLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHR-------KEHYLSGAQEPDSMA 152
L++D A LV+CGS QG C L DL G H H+ PD +A
Sbjct: 123 LVLDPALPALVSCGSSLQGRCF---LHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVA 179
Query: 153 G------VIVEQGQGPSKLFVGTAVDGK--SEYFP-TLSSRKLISDEDSADMFSLVYQDE 203
+VEQGQ S +V +++D + + P ++S R+L +D +
Sbjct: 180 SPLGTRVTVVEQGQA-SYFYVASSLDAAVAASFSPRSVSIRRLKADASG-------FAPG 231
Query: 204 FVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIV 263
FV+ + +P +S + I Y++ F + +FVYFLT+Q + T +++
Sbjct: 232 FVALSV-LPKHLVS----YSIEYVHSFHTGAFVYFLTVQPASV-----TDDPSALHTRLA 281
Query: 264 RMCAGDSEFYSYVEFPIGCSWR-----------GVEYRLVQSAHLAKPGLLLAQALGVPA 312
R+ A + E Y E + C + G Y +++ AH A G LA L +
Sbjct: 282 RLSATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAE 341
Query: 313 DEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSC---------YRGEGTL 363
++VLF +F G+ +++C F + ++ I ++ C RG
Sbjct: 342 GQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLRRGLDFF 401
Query: 364 ALPWL---------LNKELPCINTPMQINGNFCGL-VLNQPLGGLHVIEGLPLLADSTDG 413
P L+ C + P+ ++ +F + + N LG + V
Sbjct: 402 QSPSFCPNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQV------------- 448
Query: 414 MASVAAYTYR--QHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVV--DGSPILRDLLFS 469
A Y R +V +GT G + +V + + LY + + G P+ RD+
Sbjct: 449 ---TALYVTRLDNVTVAHMGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRL 505
Query: 470 PDHRHIYLLSEKQVSQLPVE--TCEQYQSCAACLGSGD-PHCGWCVLRHRCCREGACLGA 526
D H+ S QV Q+P++ C + +C CL + CGWC + C ++ C G+
Sbjct: 506 GD--HLLFASGDQVFQVPIQGPGCRHFLTCGRCLRAWHFMGCGWC--GNMCGQQKECPGS 561
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 75.1 bits (183), Expect = 6e-13
Identities = 115/578 (19%), Positives = 204/578 (35%), Gaps = 106/578 (18%)
Query: 100 LLIDYAARRLVACGSI-WQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQ 158
+L+ Y L CG+ + C F+ L D + L P S V+ +
Sbjct: 130 VLVSYNVTHLYTCGTFAFSPACTFIELQDSYLL----------------PISEDKVMEGK 173
Query: 159 GQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSL 218
GQ P D ++ L L S + + S + SQ + +D
Sbjct: 174 GQSP--------FDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLR 225
Query: 219 YPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGD--------S 270
+ D ++ S VYF + ++ E+ TS++ R+C D
Sbjct: 226 WLHHDASFVAAIPSTQVVYFFFEETASEFDFF----ERLHTSRVARVCKNDVGGEKLLQK 281
Query: 271 EFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDV---LFTIFSQGQKN 327
++ ++++ + C+ G P ++ A+ +PAD ++ +F+ +
Sbjct: 282 KWTTFLKAQLLCTQPG-----------QLPFNVIRHAVLLPADSPTAPHIYAVFTS--QW 328
Query: 328 RASPPRQTILCLFTLSNINAHIRRRIQ---------SCYRGEGTLALPWLLNKELPCINT 378
+ R + +C F+L +I + + + + YRG T P +
Sbjct: 329 QVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPSSDKA 388
Query: 379 PMQINGNFC--GLVLNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGS 436
+ +F V+ PL +E L ++ G+ H V+++GT +GS
Sbjct: 389 LTFMKDHFLMDEQVVGTPLLVKSGVEYTRLAVETAQGLDG------HSHLVMYLGTTTGS 442
Query: 437 LKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQS 496
L K V G AHL E + + +R+L +P +++ V ++P C Y+S
Sbjct: 443 LHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYES 502
Query: 497 CAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGV 556
C C+ + DPHC W CC L A + + +++ R P + P
Sbjct: 503 CVDCVLARDPHCAWDPESRTCC----LLSAPNLNSWKQDME-----RGNPEWACASGP-- 551
Query: 557 QLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVR 616
+S + E + +P+ L P P L L + HG
Sbjct: 552 -----------MSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPE 600
Query: 617 LQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPC 654
A YN S+L VG Y C
Sbjct: 601 --------------ASSTVYNGSLLLIVQDGVGGLYQC 624
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 69.3 bits (168), Expect = 3e-11
Identities = 56/166 (33%), Positives = 78/166 (46%), Gaps = 18/166 (10%)
Query: 406 LLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRD 465
L+AD G+ A YT V+FIGT G L K G HL E + + D P +R
Sbjct: 423 LVADRVTGLDG-ATYT-----VLFIGTGDGWLLKAVSLG-PWVHLIEELQLFDQEP-MRS 474
Query: 466 LLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLG 525
L+ S + ++ S Q+ QLPV C +Y+SCA C+ + DP+C W V RC G G
Sbjct: 475 LVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSG 534
Query: 526 A--------SAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTVTLH 563
+ S G L +VR P N++V + G L + H
Sbjct: 535 SLLIQHVMTSDTSGIC-NLRGSKKVRPTPKNITVVA-GTDLVLPCH 578
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 69.3 bits (168), Expect = 3e-11
Identities = 85/347 (24%), Positives = 133/347 (38%), Gaps = 36/347 (10%)
Query: 840 PRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEME 899
P + I P G E GT +TIVG S V + V V C+ + + + + C++
Sbjct: 1067 PLVLAISPSQGSYEEGTILTIVGSGFSP-SSAVTVSVGPVGCSLLS---VDEKELKCQI- 1121
Query: 900 ESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSS 959
L S PV + + D E+ Y + P G +GGT LT+SG
Sbjct: 1122 --LNGSAGHAPVAVSMADVGLAQNVGGEEFYFVYQSQISHIWPDSGSIAGGTLLTLSGFG 1179
Query: 960 LDAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTY 1019
+ S+ V V + C + D I C +P T G +T +A + Y
Sbjct: 1180 FNENSK--VLVGNETCNVIEGDLNRITCRTPKKTEGTVDISVTTNGFQAT-ARDAFSYNC 1236
Query: 1020 TQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVI--NDTAM 1077
Q P +T P I G +T+ G + + G TCQ++ N T +
Sbjct: 1237 LQTPIITDFSPKVRTILGEVNLTIKGYNFGNELTQNMAVYVGG----KTCQILHWNFTDI 1292
Query: 1078 LCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLD 1137
C P + G+ + + +GF T LN S S P S
Sbjct: 1293 RCLLPKLSPGKHDIYVEVRN---WGF----ASTRDKLNSSIQYVLEVTSMFPQRGS---- 1341
Query: 1138 VKPGSHVVLK--GKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLL 1182
+ G+ + ++ G + IPA TVL+G PC++T S ++
Sbjct: 1342 LFGGTEITIRGFGFSTIPA-------ENTVLLGSIPCNVTSSSENVI 1381
Score = 59.7 bits (143), Expect = 3e-08
Identities = 79/355 (22%), Positives = 136/355 (38%), Gaps = 48/355 (13%)
Query: 840 PRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEME 899
P IT + P G +V I G+ LG + ++ + + + +I ++ I
Sbjct: 1749 PYITGVFP--NSVIGSVKVLIEGEGLGTVLEDIAVFIGNQQFRAIE---VNENNIT---- 1799
Query: 900 ESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSS 959
+LV P G + V S + V S P +SP+ G GGT L I+G+
Sbjct: 1800 -ALVTPLPVGHHSVSVVVGSKGLALGNLTVSS---PPVASLSPTSGSIGGGTTLVITGNG 1855
Query: 960 LDAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTY 1019
G+ TVT+ D CQ + + + C +P T G + + I I+ P L++TY
Sbjct: 1856 FYPGN-TTVTIGDEPCQIISINPNEVYCRTPAGTTG----MVDVKIFVNTIAYPPLLFTY 1910
Query: 1020 TQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLC 1079
+ T S T I ++G++ + + I+ T + ND+ + C
Sbjct: 1911 ALEDTPFLRGIIPSRGPPGTEIEITGSN-FGFEILEISVMINNIQCNVT--MANDSVVQC 1967
Query: 1080 KAPGIFLGRPQPRAQGEHP-DEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDV 1138
G+H F ++ H +++ F Y P + ++
Sbjct: 1968 -------------IVGDHAGGTFPVMMHHKTKGSAMSTVVFEY----------PLNIQNI 2004
Query: 1139 KPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCS---LTVSDTQLLCDSPSQTG 1190
P G+ + G + N +L+ G C+ L T LLC+ PS G
Sbjct: 2005 NPSQGSFGGGQTMTVTGTGFNPQNSIILVCGSECAIDRLRSDYTTLLCEIPSNNG 2059
Score = 52.0 bits (123), Expect = 5e-06
Identities = 53/206 (25%), Positives = 91/206 (44%), Gaps = 23/206 (11%)
Query: 813 RCQLRTHCPAPKTNWMHLSQKGTRCS-----HP-RITQIHPLVGPKEGGTRVTIVGDNLG 866
+C + H MH KG+ S +P I I+P G GG +T+ G G
Sbjct: 1966 QCIVGDHAGGTFPVMMHHKTKGSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGT--G 2023
Query: 867 LLSREVGLRVAGVRC--NSIPAEYISAERIVCEMEESLVPSPPPGPVELC-VGDCSADFR 923
+ + V G C + + ++Y + ++CE+ + G + C V +
Sbjct: 2024 FNPQNSIILVCGSECAIDRLRSDYTT---LLCEIPSN----NGTGAEQACEVSVVNGKDL 2076
Query: 924 TQSEQVYSF---VTPTFDQVSPSRGPASGGTRLTISGSSLDAGSR-VTVTVRDSECQFVR 979
+QS +++ +TP VSP RG +GGTRLT+ GS V +T+ +++C
Sbjct: 2077 SQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIAEAKCDVEY 2136
Query: 980 RDAKAIVCISPLSTLGPSQAPITLAI 1005
+ I+C++ TL AP+ + I
Sbjct: 2137 SNKTHIICMTDAHTLS-GWAPVCVHI 2161
Score = 51.2 bits (121), Expect = 9e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 914 CVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDS 973
C GDC + + +TP +SPS+G GT LTI GS S VTV+V
Sbjct: 1053 CSGDCGFTWDSN-------ITPLVLAISPSQGSYEEGTILTIVGSGFSPSSAVTVSVGPV 1105
Query: 974 ECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWS 1033
C + D K + C + G + +++A + G + + ++ + P
Sbjct: 1106 GCSLLSVDEKELKCQILNGSAGHAPVAVSMADVGLAQNVGGEEFYFVYQSQISHIWPDSG 1165
Query: 1034 IINGSTAITVSG 1045
I G T +T+SG
Sbjct: 1166 SIAGGTLLTLSG 1177
Score = 49.7 bits (117), Expect = 3e-05
Identities = 49/215 (22%), Positives = 86/215 (40%), Gaps = 24/215 (11%)
Query: 840 PRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEME 899
P + I P GP GT + I G N G E+ + + ++CN A + IV +
Sbjct: 1916 PFLRGIIPSRGPP--GTEIEITGSNFGFEILEISVMINNIQCNVTMANDSVVQCIVGDHA 1973
Query: 900 ESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTP---TFDQVSPSRGPASGGTRLTIS 956
P +T+ + + V ++PS+G GG +T++
Sbjct: 1974 GGTFP-------------VMMHHKTKGSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTVT 2020
Query: 957 GSSLDAGSRVTVTVRDSECQF--VRRDAKAIVCISPLST-LGPSQAPITLAIDRANISSP 1013
G+ + + + + V SEC +R D ++C P + G QA ++ ++S
Sbjct: 2021 GTGFNPQNSI-ILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEVSVVNGKDLSQS 2079
Query: 1014 GLIYTYTQD--PTVTRLEPTWSIINGSTAITVSGT 1046
+TY P +T + P G T +TV G+
Sbjct: 2080 MTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGS 2114
Score = 36.6 bits (83), Expect = 0.24
Identities = 71/361 (19%), Positives = 120/361 (33%), Gaps = 72/361 (19%)
Query: 840 PRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEME 899
P I + P G G T VTI G + S V + + C + Y + E
Sbjct: 1659 PNIDLVLPNAGSTTGMTSVTIKGSGFAVSSAGVKVLMGHFPCKVLSVNYTAIECETSPAA 1718
Query: 900 ESLVPSP--PPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISG 957
+ LV G C G+C+ + E + ++T F G ++ I G
Sbjct: 1719 QQLVDVDLLIHGVPAQCQGNCTFSY---LESITPYITGVFP------NSVIGSVKVLIEG 1769
Query: 958 SSLDAG-SRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPIT-----LAIDRANIS 1011
L + V + + + + + + I + +G + LA+ +S
Sbjct: 1770 EGLGTVLEDIAVFIGNQQFRAIEVNENNITALVTPLPVGHHSVSVVVGSKGLALGNLTVS 1829
Query: 1012 SPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETT----N 1067
S P V L PT I G T + ++G Y G T
Sbjct: 1830 S----------PPVASLSPTSGSIGGGTTLVITGNGF-----------YPGNTTVTIGDE 1868
Query: 1068 TCQV--INDTAMLCKAPGIFLGRPQPR----AQGEHPDEFGFLLDHVQTARSLNRSSFTY 1121
CQ+ IN + C+ P G + P F + L+ R + S
Sbjct: 1869 PCQIISINPNEVYCRTPAGTTGMVDVKIFVNTIAYPPLLFTYALEDTPFLRGIIPSR--- 1925
Query: 1122 YPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQL 1181
GP PG+ + + G N G L +V+I C++T+++ +
Sbjct: 1926 ---------GP-------PGTEIEITGSNF-----GFEILEISVMINNIQCNVTMANDSV 1964
Query: 1182 L 1182
+
Sbjct: 1965 V 1965
Score = 34.3 bits (77), Expect = 1.2
Identities = 71/321 (22%), Positives = 127/321 (39%), Gaps = 43/321 (13%)
Query: 928 QVYSFVTPTFDQVSPSRGPASGGTRLTISG---SSLDAGSRVTVTVRDSECQFVRRDAKA 984
+V S +P+ ++PS G + +TI G S+L ++VT+ C +
Sbjct: 1559 EVSSCFSPSISNITPSTGTVN--ELITIIGHGFSNLPWANKVTIG--SYPCVVEESSEDS 1614
Query: 985 IVC-ISPLSTLGPS-QAPITLAI----DRANISSPGLIYTYTQDPTVTRLEPTWSIINGS 1038
I C I P +++ + +TL + N S + P + + P G
Sbjct: 1615 ITCHIDPQNSMDVGIRETVTLTVYNLGTAINTLSNEFDRRFVLLPNIDLVLPNAGSTTGM 1674
Query: 1039 TAITVSGTHLLTVQEPRVRAKYRGIETTNTCQV--INDTAMLCKAPGIFLGRPQPRAQGE 1096
T++T+ G+ A + + C+V +N TA+ C+ P AQ
Sbjct: 1675 TSVTIKGSGFAVSS-----AGVKVLMGHFPCKVLSVNYTAIECET--------SPAAQQL 1721
Query: 1097 HPDEFGFLLDHVQTARSLNRSSFTYYPD--PSFEPLGPSGVLDVKPGSHVVLKGKNLIPA 1154
+ LL H A+ +F+Y P + P+ V+ V+++G+ L
Sbjct: 1722 VDVD---LLIHGVPAQCQGNCTFSYLESITPYITGVFPNSVIG---SVKVLIEGEGL--- 1772
Query: 1155 AAGSSRLNYTVLIGGQPC-SLTVSDTQLLC-DSPSQTGRQPVMVLVGGLEFWLGTLHISA 1212
G+ + V IG Q ++ V++ + +P G V V+VG LG L +S+
Sbjct: 1773 --GTVLEDIAVFIGNQQFRAIEVNENNITALVTPLPVGHHSVSVVVGSKGLALGNLTVSS 1830
Query: 1213 ERALTLPAMMGLAAGGGLLLL 1233
+L G GG L++
Sbjct: 1831 PPVASLSPTSGSIGGGTTLVI 1851
Score = 33.9 bits (76), Expect = 1.5
Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 928 QVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLD-AGSRVTVTVRDSECQFVRRDAKAIV 986
Q Y+ VT F PS+G GGT LTISG D V V V C + +I
Sbjct: 267 QTYAEVTMIF----PSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILNVTENSIC 322
Query: 987 CISP 990
C +P
Sbjct: 323 CKTP 326
Score = 31.6 bits (70), Expect = 7.6
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 918 CSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSE 974
C+AD T Q+ VT ++ P G +G TRLTI G ++ V ++E
Sbjct: 18 CAADPSTDGSQIIPKVT----EIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAE 70
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 62.0 bits (149), Expect = 5e-09
Identities = 146/677 (21%), Positives = 245/677 (36%), Gaps = 141/677 (20%)
Query: 2 PSVCLLLLLFLA------------VGGALGN--RPFRAFVVTD-TTLTHLAVHRVTGEVF 46
P + LLLLL L + LG+ RPF F + T L + R ++
Sbjct: 24 PLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLY 83
Query: 47 VGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHR----LAPVDNINKLLLI 102
VGA +F L+ NL+ L G ++ + C+ + N K+LL
Sbjct: 84 VGAREALFALSSNLSFLPG---GEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILL- 139
Query: 103 DYAARRLVACGSI-WQGICQFLRLDDLFKLGEPHHRKEHYLSGAQ----EPDSMAGVIVE 157
+ L CG+ + +C ++ +++ F L G +P+ + +V
Sbjct: 140 PLSGSHLFTCGTAAFSPMCTYINMEN-FTLARDEKGNVLLEDGKGRCPFDPNFKSTALVV 198
Query: 158 QGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLS 217
G+ L+ GT V P +S + + + + + FV+S IP S
Sbjct: 199 DGE----LYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGS 252
Query: 218 LYPAFD-IYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDS------ 270
L D IY+ + F +F E S+I R+C GD
Sbjct: 253 LQGDDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVL 296
Query: 271 --EFYSYVEFPIGCSWR--GVEYRLVQSAHLAKPGLLLAQALGVPAD-EDVLFTIFSQGQ 325
+ S+++ + CS G + ++Q P P D D LF Q
Sbjct: 297 QQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPS---------PQDWRDTLFYGVFTSQ 347
Query: 326 KNRASPPRQTILCLFTLSNINA-------HIRRRIQSCYRGEGTLALPWLLNKELPCI-- 376
+R + + C+FT+ ++ + R Q Y T+ P + CI
Sbjct: 348 WHRGTTEGSAV-CVFTMKDVQRVFSGLYKEVNRETQQWY----TVTHPVPTPRPGACITN 402
Query: 377 -------NTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAYT----YRQH 425
N+ +Q+ + + L V + LL VA + + +
Sbjct: 403 SARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQAR-YQRVAVHRVPGLHHTY 461
Query: 426 SVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQ 485
V+F+GT G L K G + H+ E + + +++LL +Y S V Q
Sbjct: 462 DVLFLGTGDGRLHKAVSVGPR-VHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQ 520
Query: 486 LPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCR------------------EGA----- 522
+P+ C Y+SC CL + DP+C W C+ EGA
Sbjct: 521 VPMANCSLYRSCGDCLLARDPYCAW---SGSSCKHVSLYQPQLATRPWIQDIEGASAKDL 577
Query: 523 CLGAS--APHGFAEELSKCVQVRVRPNNVSVTS----PGVQLTVTLHNVPDLSAGVSCAF 576
C +S +P C QV+ +PN V+ + + + L N ++A SC
Sbjct: 578 CSASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCH- 636
Query: 577 EAAAENEAVLLPSGELL 593
+LP+G+LL
Sbjct: 637 ---------VLPTGDLL 644
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 62.0 bits (149), Expect = 5e-09
Identities = 146/677 (21%), Positives = 245/677 (36%), Gaps = 141/677 (20%)
Query: 2 PSVCLLLLLFLA------------VGGALGN--RPFRAFVVTD-TTLTHLAVHRVTGEVF 46
P + LLLLL L + LG+ RPF F + T L + R ++
Sbjct: 24 PLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLY 83
Query: 47 VGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHR----LAPVDNINKLLLI 102
VGA +F L+ NL+ L G ++ + C+ + N K+LL
Sbjct: 84 VGAREALFALSSNLSFLPG---GEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILL- 139
Query: 103 DYAARRLVACGSI-WQGICQFLRLDDLFKLGEPHHRKEHYLSGAQ----EPDSMAGVIVE 157
+ L CG+ + +C ++ +++ F L G +P+ + +V
Sbjct: 140 PLSGSHLFTCGTAAFSPMCTYINMEN-FTLARDEKGNVLLEDGKGRCPFDPNFKSTALVV 198
Query: 158 QGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLS 217
G+ L+ GT V P +S + + + + + FV+S IP S
Sbjct: 199 DGE----LYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGS 252
Query: 218 LYPAFD-IYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDS------ 270
L D IY+ + F +F E S+I R+C GD
Sbjct: 253 LQGDDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVL 296
Query: 271 --EFYSYVEFPIGCSWR--GVEYRLVQSAHLAKPGLLLAQALGVPAD-EDVLFTIFSQGQ 325
+ S+++ + CS G + ++Q P P D D LF Q
Sbjct: 297 QQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPS---------PQDWRDTLFYGVFTSQ 347
Query: 326 KNRASPPRQTILCLFTLSNINA-------HIRRRIQSCYRGEGTLALPWLLNKELPCI-- 376
+R + + C+FT+ ++ + R Q Y T+ P + CI
Sbjct: 348 WHRGTTEGSAV-CVFTMKDVQRVFSGLYKEVNRETQQWY----TVTHPVPTPRPGACITN 402
Query: 377 -------NTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAYT----YRQH 425
N+ +Q+ + + L V + LL VA + + +
Sbjct: 403 SARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQAR-YQRVAVHRVPGLHHTY 461
Query: 426 SVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQ 485
V+F+GT G L K G + H+ E + + +++LL +Y S V Q
Sbjct: 462 DVLFLGTGDGRLHKAVSVGPR-VHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQ 520
Query: 486 LPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCR------------------EGA----- 522
+P+ C Y+SC CL + DP+C W C+ EGA
Sbjct: 521 VPMANCSLYRSCGDCLLARDPYCAW---SGSSCKHVSLYQPQLATRPWIQDIEGASAKDL 577
Query: 523 CLGAS--APHGFAEELSKCVQVRVRPNNVSVTS----PGVQLTVTLHNVPDLSAGVSCAF 576
C +S +P C QV+ +PN V+ + + + L N ++A SC
Sbjct: 578 CSASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCH- 636
Query: 577 EAAAENEAVLLPSGELL 593
+LP+G+LL
Sbjct: 637 ---------VLPTGDLL 644
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 58.2 bits (139), Expect = 8e-08
Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 425 HSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVS 484
+ ++F+GT G + K V G H+ E V S + +L+ S +Y+ + V
Sbjct: 443 YDLLFLGTADGWIHKAVVLG-SGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVI 501
Query: 485 QLPVETCEQYQSCAACLGSGDPHCGWCVLRHRC 517
QLP+ +C +Y+SC C+ + DP+CGW H C
Sbjct: 502 QLPLSSCSRYRSCYDCILARDPYCGWDPGTHAC 534
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 14/107 (13%)
Query: 418 AAYTYRQHSVVFIGTRSGSLKKVRVD----GFQDAHLYETVPVVDGSPILRD-------- 465
+A Y+ ++V+F+G+ +G + KV D+ L E + + + +
Sbjct: 429 SAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVI 488
Query: 466 -LLFSPDHRHIYLLSEKQVSQLPVETCEQYQSC-AACLGSGDPHCGW 510
L DH +Y+ + ++P+ CE+Y SC +C+ S DP+CGW
Sbjct: 489 SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 14/107 (13%)
Query: 418 AAYTYRQHSVVFIGTRSGSLKKVRVD----GFQDAHLYETVPVVDGSPILRD-------- 465
+A Y+ ++V+F+G+ +G + KV D+ L E + + + +
Sbjct: 429 SAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVI 488
Query: 466 -LLFSPDHRHIYLLSEKQVSQLPVETCEQYQSC-AACLGSGDPHCGW 510
L DH +Y+ + ++P+ CE+Y SC +C+ S DP+CGW
Sbjct: 489 SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 14/107 (13%)
Query: 418 AAYTYRQHSVVFIGTRSGSLKKVRVD----GFQDAHLYETVPVVDGSPILRD-------- 465
+A Y+ ++V+F+G+ +G + KV D+ L E + + + +
Sbjct: 429 SAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVI 488
Query: 466 -LLFSPDHRHIYLLSEKQVSQLPVETCEQYQSC-AACLGSGDPHCGW 510
L DH +Y+ + ++P+ CE+Y SC +C+ S DP+CGW
Sbjct: 489 SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 14/107 (13%)
Query: 418 AAYTYRQHSVVFIGTRSGSLKKVRVD----GFQDAHLYETVPVVDGSPILRD-------- 465
+A Y+ ++V+F+G+ +G + KV D+ L E + + + +
Sbjct: 429 SAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVI 488
Query: 466 -LLFSPDHRHIYLLSEKQVSQLPVETCEQYQSC-AACLGSGDPHCGW 510
L DH +Y+ + ++P+ CE+Y SC +C+ S DP+CGW
Sbjct: 489 SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 14/107 (13%)
Query: 418 AAYTYRQHSVVFIGTRSGSLKKVRVD----GFQDAHLYETVPVVDGSPILRD-------- 465
+A Y+ ++V+F+G+ +G + KV D+ L E + + + +
Sbjct: 429 SAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVI 488
Query: 466 -LLFSPDHRHIYLLSEKQVSQLPVETCEQYQSC-AACLGSGDPHCGW 510
L DH +Y+ + ++P+ CE+Y SC +C+ S DP+CGW
Sbjct: 489 SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 51.6 bits (122), Expect = 7e-06
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 6/98 (6%)
Query: 425 HSVVFIGTRSGSLKKVRVDGFQDAH-----LYETVPVVDGSPILRDLLFSPDHRHIYLLS 479
+ V++IGT SG++ K + H +P P LR L R +++
Sbjct: 486 YHVLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREP-LRSLRILHSARALFVGL 544
Query: 480 EKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRC 517
V ++P+E C Y+S ACLG+ DP+CGW + RC
Sbjct: 545 RDGVLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRC 582
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 49.7 bits (117), Expect = 3e-05
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 6/89 (6%)
Query: 427 VVFIGTRSGSLKKVRVDGFQDA----HLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQ 482
V+++ T G++ KV G Q+ ++ E P + I + + + R +Y+ S+ +
Sbjct: 426 VLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI-QTMSLDAERRKLYVSSQWE 484
Query: 483 VSQLPVETCEQY-QSCAACLGSGDPHCGW 510
VSQ+P++ CE Y C CL S DP+CGW
Sbjct: 485 VSQVPLDLCEVYGGGCHGCLMSRDPYCGW 513
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 49.7 bits (117), Expect = 3e-05
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 6/89 (6%)
Query: 427 VVFIGTRSGSLKKVRVDGFQDA----HLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQ 482
V+++ T G++ KV G Q+ ++ E P + I + + + R +Y+ S+ +
Sbjct: 261 VLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI-QTMSLDAERRKLYVSSQWE 319
Query: 483 VSQLPVETCEQY-QSCAACLGSGDPHCGW 510
VSQ+P++ CE Y C CL S DP+CGW
Sbjct: 320 VSQVPLDLCEVYGGGCHGCLMSRDPYCGW 348
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,071,384
Number of Sequences: 37866
Number of extensions: 3543020
Number of successful extensions: 8733
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 8277
Number of HSP's gapped (non-prelim): 203
length of query: 1871
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1754
effective length of database: 13,817,196
effective search space: 24235361784
effective search space used: 24235361784
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.