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Search of human proteins with 5902134
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5902134 coronin, actin binding protein, 1A [Homo sapiens]
(461 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5902134 coronin, actin binding protein, 1A [Homo sapiens] 942 0.0
gi|65787364 coronin, actin binding protein, 1B [Homo sapiens] 659 0.0
gi|14149734 coronin, actin binding protein, 1B [Homo sapiens] 659 0.0
gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo sa... 645 0.0
gi|109627650 coronin 6 [Homo sapiens] 637 0.0
gi|148529011 coronin, actin binding protein, 2B [Homo sapiens] 408 e-114
gi|209529711 coronin, actin binding protein, 2A [Homo sapiens] 396 e-110
gi|16554585 coronin, actin binding protein, 2A [Homo sapiens] 396 e-110
gi|168229161 coronin 7 [Homo sapiens] 240 2e-63
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 75 2e-13
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 75 2e-13
gi|16554629 WD repeat domain 5 [Homo sapiens] 72 1e-12
gi|16554627 WD repeat domain 5 [Homo sapiens] 72 1e-12
gi|23199987 WD repeat domain 5B [Homo sapiens] 63 5e-10
gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 63 5e-10
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 63 5e-10
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 63 6e-10
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 62 1e-09
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 62 1e-09
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 62 1e-09
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 61 2e-09
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 61 2e-09
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 61 2e-09
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 59 7e-09
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 59 7e-09
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 58 2e-08
gi|19913367 transducin beta-like 1Y [Homo sapiens] 58 2e-08
gi|19913365 transducin beta-like 1Y [Homo sapiens] 58 2e-08
gi|15150805 transducin beta-like 1Y [Homo sapiens] 58 2e-08
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 56 6e-08
>gi|5902134 coronin, actin binding protein, 1A [Homo sapiens]
Length = 461
Score = 942 bits (2436), Expect = 0.0
Identities = 461/461 (100%), Positives = 461/461 (100%)
Query: 1 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 60
MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
Sbjct: 1 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 60
Query: 61 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 120
VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
Sbjct: 61 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 120
Query: 121 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 180
REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
Sbjct: 121 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 180
Query: 181 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 240
SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
Sbjct: 181 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 240
Query: 241 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 300
RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
Sbjct: 241 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 300
Query: 301 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 360
APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
Sbjct: 301 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 360
Query: 361 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 420
EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
Sbjct: 361 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 420
Query: 421 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK 461
ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
Sbjct: 421 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK 461
>gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 659 bits (1699), Expect = 0.0
Identities = 316/477 (66%), Positives = 385/477 (80%), Gaps = 24/477 (5%)
Query: 3 RQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVL 62
R+VVR SKFRHVFGQP K DQCYED+RVS+ TWDS FCAVNPKF+A+I EASGGGAFLVL
Sbjct: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
Query: 63 PLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLRE 122
PL KTGR+DK PTVCGHT PVLDI WCPHND VIASGSEDCTVMVW+IP+ GL PL E
Sbjct: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
Query: 123 PVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSV 182
PVV LEGHTKRVGI+AWH TA+NVLLSAGCDNV+++W+VGT + L +HPD IY+V
Sbjct: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLD-SLHPDLIYNV 182
Query: 183 DWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRM 242
W+ +G L C++C+DK VRII+PR+GT+VAE+++ HEG RP+RA+F+++GK+ TTGFSRM
Sbjct: 183 SWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRM 242
Query: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
SERQ+ALWD ++LEEP++LQELD+S+G LLPF+DPDT++VY+CGKGDSSIRYFEIT E P
Sbjct: 243 SERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPP 302
Query: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQED 362
++H+L+ F+SKE QRGMG MPKRGLEV+KCEIARFYKLHER+CEPI MTVPRKSDLFQ+D
Sbjct: 303 YIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDD 362
Query: 363 LYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRAAP- 419
LYP TAGP+ AL AEEW+ GRDA P+LISL++ YVP K R+L+++R L R AP
Sbjct: 363 LYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPG 422
Query: 420 ------EASGTPSSDA-----------VSRLEE---EMRKLQATVQELQKRLDRLEE 456
AS T ++DA +LEE E+R L+A V+E R+ RLEE
Sbjct: 423 SSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE 479
>gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 659 bits (1699), Expect = 0.0
Identities = 316/477 (66%), Positives = 385/477 (80%), Gaps = 24/477 (5%)
Query: 3 RQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVL 62
R+VVR SKFRHVFGQP K DQCYED+RVS+ TWDS FCAVNPKF+A+I EASGGGAFLVL
Sbjct: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
Query: 63 PLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLRE 122
PL KTGR+DK PTVCGHT PVLDI WCPHND VIASGSEDCTVMVW+IP+ GL PL E
Sbjct: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
Query: 123 PVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSV 182
PVV LEGHTKRVGI+AWH TA+NVLLSAGCDNV+++W+VGT + L +HPD IY+V
Sbjct: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLD-SLHPDLIYNV 182
Query: 183 DWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRM 242
W+ +G L C++C+DK VRII+PR+GT+VAE+++ HEG RP+RA+F+++GK+ TTGFSRM
Sbjct: 183 SWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRM 242
Query: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
SERQ+ALWD ++LEEP++LQELD+S+G LLPF+DPDT++VY+CGKGDSSIRYFEIT E P
Sbjct: 243 SERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPP 302
Query: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQED 362
++H+L+ F+SKE QRGMG MPKRGLEV+KCEIARFYKLHER+CEPI MTVPRKSDLFQ+D
Sbjct: 303 YIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDD 362
Query: 363 LYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRAAP- 419
LYP TAGP+ AL AEEW+ GRDA P+LISL++ YVP K R+L+++R L R AP
Sbjct: 363 LYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPG 422
Query: 420 ------EASGTPSSDA-----------VSRLEE---EMRKLQATVQELQKRLDRLEE 456
AS T ++DA +LEE E+R L+A V+E R+ RLEE
Sbjct: 423 SSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE 479
>gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo
sapiens]
Length = 474
Score = 645 bits (1663), Expect = 0.0
Identities = 302/467 (64%), Positives = 383/467 (82%), Gaps = 14/467 (2%)
Query: 3 RQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVL 62
R+VVR SKFRHVFGQ K DQCY+D+RVS+ TWDS FCAVNP+FVA+I EASGGGAFLVL
Sbjct: 2 RRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVL 61
Query: 63 PLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLRE 122
PL KTGR+DK+ PTVCGHT PVLDI WCPHND VIASGSEDCTVMVW+IP+ GL L L E
Sbjct: 62 PLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTE 121
Query: 123 PVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSV 182
PVV LEGH+KRVGIVAWH TA+NVLLSAGCDN I++W+VGTG A++ L ++H D IY+V
Sbjct: 122 PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIYNV 180
Query: 183 DWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRM 242
W+R+G LICT+ +DK+VR+I+PRK +VAEK++ HEG RP+RA+F+++G + TTGFSRM
Sbjct: 181 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM 240
Query: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
SERQ+ALW+ K+++EP++L E+DTS+GVLLPF+DPDT+I+YLCGKGDSSIRYFEIT E+P
Sbjct: 241 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP 300
Query: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQED 362
++HYL+ FSSKE QRGMGYMPKRGL+VNKCEIARF+KLHER+CEPI MTVPRKSDLFQ+D
Sbjct: 301 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD 360
Query: 363 LYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNR-----GLDTGRRRA 417
LYP TAGP+ AL AEEW G++A P+LISLK GY+P K+R+L+V + T ++
Sbjct: 361 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC 420
Query: 418 -----APEASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEE 456
+ + T S ++L+E E++ ++ T+ +R+ +LE+
Sbjct: 421 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQ 467
>gi|109627650 coronin 6 [Homo sapiens]
Length = 472
Score = 637 bits (1642), Expect = 0.0
Identities = 310/463 (66%), Positives = 378/463 (81%), Gaps = 10/463 (2%)
Query: 1 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 60
MSR+VVR SKFRHVFGQ AKADQ YED+RVS+ TWDS FCAVNPKF+A+I EA GGGAF+
Sbjct: 1 MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFI 60
Query: 61 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 120
VLPL KTGRVDKN P V GHTAPVLDI WCPHNDNVIAS S+D T+MVW+IPD M +
Sbjct: 61 VLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNI 120
Query: 121 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 180
EP++TLEGH+KRVGI++WH TA+NVLLSAG DNVI++W+VGTG +L+L ++HPD I+
Sbjct: 121 TEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLD-DMHPDVIH 179
Query: 181 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 240
SV W+ +G L+ T+C+DK +RII+PRKG VVAE+ HEG RP+RAVF +G I TTGF+
Sbjct: 180 SVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFT 239
Query: 241 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 300
RMS+R++ LWD + EEP++LQE+DTS+GVLLPF+DPD++IVYLCGKGDSSIRYFEIT E
Sbjct: 240 RMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDE 299
Query: 301 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 360
PF+HYL+ FSSKE QRGMG+MPKRGL+V+KCEIARFYKLHER+CEPI MTVPRKSDLFQ
Sbjct: 300 PPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQ 359
Query: 361 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD----TGR 414
+DLYP T GP+PAL A+EWL G+DA P+LISL+DGYVPPK RELRV + LD +G
Sbjct: 360 DDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGP 419
Query: 415 RRAAPEASGTPSSD--AVSRLEEEMRKLQATVQELQKRLDRLE 455
RR + AS P S + L EE++ L+ VQ ++R+ LE
Sbjct: 420 RR-SQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALE 461
>gi|148529011 coronin, actin binding protein, 2B [Homo sapiens]
Length = 480
Score = 408 bits (1049), Expect = e-114
Identities = 207/473 (43%), Positives = 304/473 (64%), Gaps = 23/473 (4%)
Query: 3 RQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVL 62
R RSSKFR+V+G+ A + C++ + +++ D+ FCAVN +F+A++ E++GGG+FLV+
Sbjct: 9 RPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVI 68
Query: 63 PLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLRE 122
PL +TGR++ N P VCGH VLDI W P DN+IAS SED +V +WEIP+GGL + E
Sbjct: 69 PLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTE 128
Query: 123 PVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSV 182
++ L GH++RVG+V WH T N+L SAG D +++W++ G + + + H D I +
Sbjct: 129 ALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMI--DCHTDVILCM 186
Query: 183 DWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGK-ILTTGFSR 241
++ DG L+ T+C+DK++R+IEPR G V+ E + + R R VF+ K +LTTG SR
Sbjct: 187 SFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNH--RVNRVVFLGNMKRLLTTGVSR 244
Query: 242 MSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEA 301
+ RQ+ALWD + L PL +E+D SG+L PF+D DT+++YL GKGD +IRY+EI++E
Sbjct: 245 WNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEK 304
Query: 302 PFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERR--CEPIAMTVPRKSDLF 359
P+L YL F S Q+G+G MPK GL+V+ CE+ RFYKL + EPI+M VPR+SD +
Sbjct: 305 PYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSY 364
Query: 360 QEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGY---------VPPKSRELRVNRGL 410
QED+YP T G +PALT +EWLGG + P+L+SLK+GY P K ++ V G+
Sbjct: 365 QEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVVNGI 424
Query: 411 DTGRRRAAPEASGT------PSSDAVSRLEEEMRKLQATVQELQKRLDRLEET 457
D P D + RL+EE+ + +++LQ L L +
Sbjct: 425 DL-LENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNS 476
>gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 396 bits (1017), Expect = e-110
Identities = 194/419 (46%), Positives = 282/419 (67%), Gaps = 8/419 (1%)
Query: 7 RSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLGK 66
RSSKFRHVFG+PA + CY+ V ++++ D+ FCAVNP F+A++ E +GGGAFLV+PL +
Sbjct: 8 RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
Query: 67 TGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVT 126
TG++D + P VCGH VLD+ W P +D IAS SED T+ +W IP L L
Sbjct: 68 TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
Query: 127 LEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEV---HPDTIYSVD 183
L GH +RVG+V WH TA N+L SAG D +M+W++ T +++T H D I S+
Sbjct: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
Query: 184 WSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSE-GKILTTGFSRM 242
++ +G L+ T+C+D+++R+I+PR GTV+ E ++G R + +F+ K+++TG SR
Sbjct: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQEAS--YKGHRASKVLFLGNLKKLMSTGTSRW 245
Query: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
+ RQVALWD +L PL ++LD SSGVL PF+D DT+++Y+ GKGD +IRY+E++++ P
Sbjct: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
Query: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERR--CEPIAMTVPRKSDLFQ 360
L YL+ + S Q+G+G MPKRGL+V+ CEI RFYKL + EPI+M VPR+S+ +Q
Sbjct: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
Query: 361 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAP 419
ED+YPPTAG P+LTA+EWL G + P+L+SL+ G + L R + A+P
Sbjct: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMAPASP 424
>gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 396 bits (1017), Expect = e-110
Identities = 194/419 (46%), Positives = 282/419 (67%), Gaps = 8/419 (1%)
Query: 7 RSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLGK 66
RSSKFRHVFG+PA + CY+ V ++++ D+ FCAVNP F+A++ E +GGGAFLV+PL +
Sbjct: 8 RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
Query: 67 TGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVT 126
TG++D + P VCGH VLD+ W P +D IAS SED T+ +W IP L L
Sbjct: 68 TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
Query: 127 LEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEV---HPDTIYSVD 183
L GH +RVG+V WH TA N+L SAG D +M+W++ T +++T H D I S+
Sbjct: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
Query: 184 WSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSE-GKILTTGFSRM 242
++ +G L+ T+C+D+++R+I+PR GTV+ E ++G R + +F+ K+++TG SR
Sbjct: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQEAS--YKGHRASKVLFLGNLKKLMSTGTSRW 245
Query: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
+ RQVALWD +L PL ++LD SSGVL PF+D DT+++Y+ GKGD +IRY+E++++ P
Sbjct: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
Query: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERR--CEPIAMTVPRKSDLFQ 360
L YL+ + S Q+G+G MPKRGL+V+ CEI RFYKL + EPI+M VPR+S+ +Q
Sbjct: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
Query: 361 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAP 419
ED+YPPTAG P+LTA+EWL G + P+L+SL+ G + L R + A+P
Sbjct: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMAPASP 424
>gi|168229161 coronin 7 [Homo sapiens]
Length = 925
Score = 240 bits (613), Expect = 2e-63
Identities = 155/456 (33%), Positives = 238/456 (52%), Gaps = 19/456 (4%)
Query: 8 SSKFRHVFGQPAKADQCYEDVRVSQTTW---DSGFCAVNPKFVALICEASGGGAFLVLPL 64
SSKFRH G D +++ T GFCA K + S GG VL L
Sbjct: 470 SSKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCA--NKLRVAVPLLSSGGQVAVLEL 527
Query: 65 GKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPV 124
K GR+ A + A V D+AW P + + +A ED + +W +P GL L P
Sbjct: 528 RKPGRLPDTALPTLQNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTTPE 587
Query: 125 VTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDW 184
L GHT+++ + +H A NVL S+ D + +WD+ GA L L + H D I+S+ W
Sbjct: 588 TVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKL--QGHQDQIFSLAW 645
Query: 185 SRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGK-ILTTGFSRMS 243
S DG + T C+D RVR+ PR G ++ +G R R V+V +G+ +L +GF S
Sbjct: 646 SPDGQQLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQS 705
Query: 244 ERQVALWDTKHLE-EPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
ERQ+ L++ + L PL++ LD + LLP +DPDT +V L GKGD+ + +E+ E+P
Sbjct: 706 ERQLLLYEAEALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLPESP 765
Query: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPR-KSDLFQE 361
F + F+S + +G+ +PK +V + E+ R +L + EP+A +PR + + FQ+
Sbjct: 766 FFLECNSFTSPDPHKGLVLLPKTECDVREVELMRCLRLRQSSLEPVAFRLPRVRKEFFQD 825
Query: 362 DLYPPTAGP-DPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 420
D++P TA +P L+AE WL G + P L+SL+ + P S+ R R AP
Sbjct: 826 DVFPDTAVIWEPVLSAEAWLQGANGQPWLLSLQPPDMSPVSQAPR------EAPARRAPS 879
Query: 421 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEE 456
++ + + +EE+ L A V +L R D L +
Sbjct: 880 SAQYLEEKSDQQKKEEL--LNAMVAKLGNREDPLPQ 913
Score = 208 bits (530), Expect = 7e-54
Identities = 130/424 (30%), Positives = 204/424 (48%), Gaps = 7/424 (1%)
Query: 7 RSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLGK 66
R SKFRH +P + + D+R + +A + G ++PL
Sbjct: 5 RVSKFRHTEARPPRRESWISDIRAGTAPSCRNHIKSSCSLIAF--NSDRPGVLGIVPLQG 62
Query: 67 TGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVT 126
G + + H+ V D+ + P +D ++A+GS D TV +W +P G LP P V
Sbjct: 63 QGEDKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALP-SAPGVV 121
Query: 127 LEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSR 186
L V ++ +H T+ +L+SA + VWD + L H D + S WSR
Sbjct: 122 LGPEDLPVEVLQFHPTSDGILVSAA-GTTVKVWDAAKQQPLTELA--AHGDLVQSAVWSR 178
Query: 187 DGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGK-ILTTGFSRMSER 245
DG L+ T+C+DK++RI +PR ++ + HE +R R ++ + +++TGF++M ER
Sbjct: 179 DGALVGTACKDKQLRIFDPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGFNQMRER 238
Query: 246 QVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLH 305
+V LWDT+ L+ LDTS G L+P DPD+ ++ L GKG+ + +E+ + P L
Sbjct: 239 EVKLWDTRFFSSALASLTLDTSLGCLVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALS 298
Query: 306 YLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQEDLYP 365
++ + RG +P++ L V CE+ R +L + PI VPRK+ F EDL+P
Sbjct: 299 PVTQCVLESVLRGAALVPRQALAVMSCEVLRVLQLSDTAIVPIGYHVPRKAVEFHEDLFP 358
Query: 366 PTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPEASGTP 425
TAG PA W G + +SL P S + + A P TP
Sbjct: 359 DTAGCVPATDPHSWWAGDNQQVQKVSLNPACRPHPSFTSCLVPPAEPLPDTAQPAVMETP 418
Query: 426 SSDA 429
DA
Sbjct: 419 VGDA 422
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 74.7 bits (182), Expect = 2e-13
Identities = 59/237 (24%), Positives = 102/237 (43%), Gaps = 16/237 (6%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
HT V D+ + P ++ S S D T+ VW++ D G M+ + L GH V A+
Sbjct: 169 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKV------LRGHQNWVYSCAF 222
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDKR 199
+ ++L S G + +W++ + L E H + + D+S DG L+ T+ D R
Sbjct: 223 SPDS-SMLCSVGASKAVFLWNMDKYTMIRKL--EGHHHDVVACDFSPDGALLATASYDTR 279
Query: 200 VRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVALWDTK-----H 254
V I +P G ++ E P+ A ++ + + FS +L D K
Sbjct: 280 VYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWR 339
Query: 255 LEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFS 311
++E +Q S+G+ F + V G D S+ ++ + P L +L S
Sbjct: 340 IDEDYPVQVAPLSNGLCCAFSTDGS--VLAAGTHDGSVYFWATPRQVPSLQHLCRMS 394
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 11/102 (10%)
Query: 103 DCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDN-VIMVWDV 161
DC +VW + G + + V +E H R G +LL+ G +N I +WDV
Sbjct: 105 DCGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFG-------QDQLLLATGLNNGRIKIWDV 157
Query: 162 GTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSC-RDKRVRI 202
TG +L L H + + + ++ DG LI S RDK +R+
Sbjct: 158 YTGKLLLNLVD--HTEVVRDLTFAPDGSLILVSASRDKTLRV 197
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 74.7 bits (182), Expect = 2e-13
Identities = 59/237 (24%), Positives = 102/237 (43%), Gaps = 16/237 (6%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
HT V D+ + P ++ S S D T+ VW++ D G M+ + L GH V A+
Sbjct: 23 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKV------LRGHQNWVYSCAF 76
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDKR 199
+ ++L S G + +W++ + L E H + + D+S DG L+ T+ D R
Sbjct: 77 SPDS-SMLCSVGASKAVFLWNMDKYTMIRKL--EGHHHDVVACDFSPDGALLATASYDTR 133
Query: 200 VRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVALWDTK-----H 254
V I +P G ++ E P+ A ++ + + FS +L D K
Sbjct: 134 VYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWR 193
Query: 255 LEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFS 311
++E +Q S+G+ F + V G D S+ ++ + P L +L S
Sbjct: 194 IDEDYPVQVAPLSNGLCCAFSTDGS--VLAAGTHDGSVYFWATPRQVPSLQHLCRMS 248
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 71.6 bits (174), Expect = 1e-12
Identities = 51/177 (28%), Positives = 86/177 (48%), Gaps = 17/177 (9%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ GH + D+AW + N++ S S+D T+ +W++ G + TL+GH+ V
Sbjct: 82 TISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCLK-------TLKGHSNYVF 133
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSC 195
++ + N+++S D + +WDV TG + TL H D + +V ++RDG LI +S
Sbjct: 134 CCNFNPQS-NLIVSGSFDESVRIWDVKTGKCLKTL--PAHSDPVSAVHFNRDGSLIVSSS 190
Query: 196 RDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVALWD 251
D RI + G + K + PV V F GK + + + + LWD
Sbjct: 191 YDGLCRIWDTASGQCL--KTLIDDDNPPVSFVKFSPNGKYI---LAATLDNTLKLWD 242
Score = 63.5 bits (153), Expect = 4e-10
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 26/182 (14%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ GHT V + + P N +AS S D + +W DG T+ GH +
Sbjct: 40 TLAGHTKAVSSVKFSP-NGEWLASSSADKLIKIWGAYDGKFEK-------TISGHKLGIS 91
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSC 195
VAW + + N+L+SA D + +WDV +G + TL + H + ++ +++ LI +
Sbjct: 92 DVAWSSDS-NLLVSASDDKTLKIWDVSSGKCLKTL--KGHSNYVFCCNFNPQSNLIVSGS 148
Query: 196 RDKRVRIIEPRKG----TVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVALW 250
D+ VRI + + G T+ A D PV AV F +G ++ S + +W
Sbjct: 149 FDESVRIWDVKTGKCLKTLPAHSD-------PVSAVHFNRDGSLIV---SSSYDGLCRIW 198
Query: 251 DT 252
DT
Sbjct: 199 DT 200
Score = 31.2 bits (69), Expect = 2.1
Identities = 37/185 (20%), Positives = 71/185 (38%), Gaps = 13/185 (7%)
Query: 66 KTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVV 125
KTG+ K P H+ PV + + + ++I S S D +W+ G + L
Sbjct: 159 KTGKCLKTLPA---HSDPVSAVHF-NRDGSLIVSSSYDGLCRIWDTASGQCLKTL----- 209
Query: 126 TLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWS 185
++ V V + + +L +A DN + +WD G + T + ++S
Sbjct: 210 -IDDDNPPVSFVKFSPNGKYIL-AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFS 267
Query: 186 RDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSER 245
GG S + + I + + +K + H A +E I + +++
Sbjct: 268 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALE--NDK 325
Query: 246 QVALW 250
+ LW
Sbjct: 326 TIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 71.6 bits (174), Expect = 1e-12
Identities = 51/177 (28%), Positives = 86/177 (48%), Gaps = 17/177 (9%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ GH + D+AW + N++ S S+D T+ +W++ G + TL+GH+ V
Sbjct: 82 TISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCLK-------TLKGHSNYVF 133
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSC 195
++ + N+++S D + +WDV TG + TL H D + +V ++RDG LI +S
Sbjct: 134 CCNFNPQS-NLIVSGSFDESVRIWDVKTGKCLKTL--PAHSDPVSAVHFNRDGSLIVSSS 190
Query: 196 RDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVALWD 251
D RI + G + K + PV V F GK + + + + LWD
Sbjct: 191 YDGLCRIWDTASGQCL--KTLIDDDNPPVSFVKFSPNGKYI---LAATLDNTLKLWD 242
Score = 63.5 bits (153), Expect = 4e-10
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 26/182 (14%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ GHT V + + P N +AS S D + +W DG T+ GH +
Sbjct: 40 TLAGHTKAVSSVKFSP-NGEWLASSSADKLIKIWGAYDGKFEK-------TISGHKLGIS 91
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSC 195
VAW + + N+L+SA D + +WDV +G + TL + H + ++ +++ LI +
Sbjct: 92 DVAWSSDS-NLLVSASDDKTLKIWDVSSGKCLKTL--KGHSNYVFCCNFNPQSNLIVSGS 148
Query: 196 RDKRVRIIEPRKG----TVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVALW 250
D+ VRI + + G T+ A D PV AV F +G ++ S + +W
Sbjct: 149 FDESVRIWDVKTGKCLKTLPAHSD-------PVSAVHFNRDGSLIV---SSSYDGLCRIW 198
Query: 251 DT 252
DT
Sbjct: 199 DT 200
Score = 31.2 bits (69), Expect = 2.1
Identities = 37/185 (20%), Positives = 71/185 (38%), Gaps = 13/185 (7%)
Query: 66 KTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVV 125
KTG+ K P H+ PV + + + ++I S S D +W+ G + L
Sbjct: 159 KTGKCLKTLPA---HSDPVSAVHF-NRDGSLIVSSSYDGLCRIWDTASGQCLKTL----- 209
Query: 126 TLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWS 185
++ V V + + +L +A DN + +WD G + T + ++S
Sbjct: 210 -IDDDNPPVSFVKFSPNGKYIL-AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFS 267
Query: 186 RDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSER 245
GG S + + I + + +K + H A +E I + +++
Sbjct: 268 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALE--NDK 325
Query: 246 QVALW 250
+ LW
Sbjct: 326 TIKLW 330
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 63.2 bits (152), Expect = 5e-10
Identities = 48/181 (26%), Positives = 84/181 (46%), Gaps = 17/181 (9%)
Query: 72 KNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHT 131
K T+ GH + D+AW + ++ S S+D T+ +W++ G + + TL+GH+
Sbjct: 74 KYEKTLYGHNLEISDVAWSSDSSRLV-SASDDKTLKLWDVRSG-------KCLKTLKGHS 125
Query: 132 KRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLI 191
V ++ + N+++S D + +W+V TG + TL H D + +V ++ G LI
Sbjct: 126 NYVFCCNFNPPS-NLIISGSFDETVKIWEVKTGKCLKTL--SAHSDPVSAVHFNCSGSLI 182
Query: 192 CTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVALW 250
+ D RI + G + K + PV V F GK + T + + LW
Sbjct: 183 VSGSYDGLCRIWDAASGQCL--KTLVDDDNPPVSFVKFSPNGKYILTA---TLDNTLKLW 237
Query: 251 D 251
D
Sbjct: 238 D 238
Score = 50.1 bits (118), Expect = 4e-06
Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Query: 69 RVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLE 128
R K T+ GH+ V + P + N+I SGS D TV +WE+ G + + TL
Sbjct: 113 RSGKCLKTLKGHSNYVFCCNFNPPS-NLIISGSFDETVKIWEVKTG-------KCLKTLS 164
Query: 129 GHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDG 188
H+ V V ++ + ++++S D + +WD +G + TL + +P + V +S +G
Sbjct: 165 AHSDPVSAVHFNCSG-SLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSF-VKFSPNG 222
Query: 189 GLICTSCRDKRVRIIEPRKG 208
I T+ D +++ + +G
Sbjct: 223 KYILTATLDNTLKLWDYSRG 242
Score = 34.7 bits (78), Expect = 0.19
Identities = 40/190 (21%), Positives = 76/190 (40%), Gaps = 15/190 (7%)
Query: 66 KTGRVDKNAPTVCGHTAPVLDIAW-CPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPV 124
KTG+ K T+ H+ PV + + C + ++I SGS D +W+ G + L
Sbjct: 155 KTGKCLK---TLSAHSDPVSAVHFNC--SGSLIVSGSYDGLCRIWDAASGQCLKTL---- 205
Query: 125 VTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDW 184
++ V V + + +L +A DN + +WD G + T + ++
Sbjct: 206 --VDDDNPPVSFVKFSPNGKYIL-TATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANF 262
Query: 185 SRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSE 244
S GG S + + I + + +K + H A +E I + ++
Sbjct: 263 SVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALE--ND 320
Query: 245 RQVALWDTKH 254
+ + LW + H
Sbjct: 321 KTIKLWMSNH 330
>gi|62234438 Notchless gene homolog isoform b [Homo sapiens]
Length = 193
Score = 63.2 bits (152), Expect = 5e-10
Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 11/124 (8%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GH A + + + P + ++AS S D ++ +W+ G + LR GH V +A
Sbjct: 78 GHQALINQVLFSP-DSRIVASASFDKSIKLWDGRTGKYLASLR-------GHVAAVYQIA 129
Query: 139 WHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDK 198
W ++ +L+S D+ + VWDV A L + H D +Y+VDWS DG + + +DK
Sbjct: 130 WSADSR-LLVSGSSDSTLKVWDVK--AQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 186
Query: 199 RVRI 202
+RI
Sbjct: 187 CLRI 190
Score = 47.4 bits (111), Expect = 3e-05
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 9/92 (9%)
Query: 68 GRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTL 127
GR K ++ GH A V IAW + ++ SGS D T+ VW++ ++ + L
Sbjct: 109 GRTGKYLASLRGHVAAVYQIAWSA-DSRLLVSGSSDSTLKVWDV-------KAQKLAMDL 160
Query: 128 EGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVW 159
GH V V W Q V S G D + +W
Sbjct: 161 PGHADEVYAVDWSPDGQRV-ASGGKDKCLRIW 191
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 63.2 bits (152), Expect = 5e-10
Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 11/124 (8%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GH A + + + P + ++AS S D ++ +W+ G + LR GH V +A
Sbjct: 370 GHQALINQVLFSP-DSRIVASASFDKSIKLWDGRTGKYLASLR-------GHVAAVYQIA 421
Query: 139 WHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDK 198
W ++ +L+S D+ + VWDV A L + H D +Y+VDWS DG + + +DK
Sbjct: 422 WSADSR-LLVSGSSDSTLKVWDVK--AQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 478
Query: 199 RVRI 202
+RI
Sbjct: 479 CLRI 482
Score = 47.4 bits (111), Expect = 3e-05
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 9/92 (9%)
Query: 68 GRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTL 127
GR K ++ GH A V IAW + ++ SGS D T+ VW++ ++ + L
Sbjct: 401 GRTGKYLASLRGHVAAVYQIAWSA-DSRLLVSGSSDSTLKVWDV-------KAQKLAMDL 452
Query: 128 EGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVW 159
GH V V W Q V S G D + +W
Sbjct: 453 PGHADEVYAVDWSPDGQRV-ASGGKDKCLRIW 483
Score = 46.2 bits (108), Expect = 6e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 19/137 (13%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GH+ V+ +A+ P +ASGS D TV W+ L P T +GH V ++
Sbjct: 112 GHSEAVISVAFSP-TGKYLASGSGDTTVRFWD-------LSTETPHFTCKGHRHWVLSIS 163
Query: 139 WHTTAQNVLLSAGCDN-VIMVWDVGTGAAM-LTLGPEVHPDTIYSVDW-----SRDGGLI 191
W + L++GC N I++WD TG + TL H I + W + + +
Sbjct: 164 WSPDGRK--LASGCKNGQILLWDPSTGKQVGRTLAG--HSKWITGLSWEPLHANPECRYV 219
Query: 192 CTSCRDKRVRIIEPRKG 208
+S +D VRI + G
Sbjct: 220 ASSSKDGSVRIWDTTAG 236
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 126 TLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWS 185
+LEGH++ V VA+ T + + +G D + WD+ T T + H + S+ WS
Sbjct: 109 SLEGHSEAVISVAFSPTGKYLASGSG-DTTVRFWDLSTETPHFTC--KGHRHWVLSISWS 165
Query: 186 RDGGLICTSCRDKRVRIIEPRKGTVV 211
DG + + C++ ++ + +P G V
Sbjct: 166 PDGRKLASGCKNGQILLWDPSTGKQV 191
Score = 33.1 bits (74), Expect = 0.54
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 9/63 (14%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GHT V + W D ++ S S+D T+ VW DG L TL+GH V +A
Sbjct: 244 GHTQSVTCLRW--GGDGLLYSASQDRTIKVWRAHDGVLCR-------TLQGHGHWVNTMA 294
Query: 139 WHT 141
T
Sbjct: 295 LST 297
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 62.8 bits (151), Expect = 6e-10
Identities = 68/279 (24%), Positives = 116/279 (41%), Gaps = 40/279 (14%)
Query: 67 TGRVDKNA-----------PTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGG 115
TG DKN T+ GHT V + + P D ++ S S D T+ +W +P+
Sbjct: 239 TGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQD-LVFSASPDATIRIWSVPNAS 297
Query: 116 LMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVH 175
V + H V ++ H T + LLS+ D D+ TG + + E
Sbjct: 298 C-------VQVVRAHESAVTGLSLHATG-DYLLSSSDDQYWAFSDIQTGRVLTKVTDETS 349
Query: 176 PDTIYSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSE-GKI 234
++ + DG + T D +++I + ++ T VA H G P+ ++ SE G
Sbjct: 350 GCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFP-GHSG--PITSIAFSENGYY 406
Query: 235 LTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPD--------TNI-VYLC 285
L T + V LWD + L+ +LQ LD + V FD T++ +Y+C
Sbjct: 407 LATA---ADDSSVKLWDLRKLKNFKTLQ-LDNNFEVKSLIFDQSGTYLALGGTDVQIYIC 462
Query: 286 GKGDSSIRYFE---ITSEAPFLHYLSMFSSKESQRGMGY 321
+ + + E +T+ F H+ +S R + +
Sbjct: 463 KQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKF 501
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 62.0 bits (149), Expect = 1e-09
Identities = 49/168 (29%), Positives = 77/168 (45%), Gaps = 25/168 (14%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEI---PDGGLMLPLREPVVTLEGHTKRVG 135
GHT V D+ W P + V AS S D ++ +W+I P ML T H V
Sbjct: 259 GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACML------TTATAHDGDVN 312
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDV---GTGAAMLTLGPEVHPDTIYSVDW-SRDGGLI 191
+++W + + LLS G D + +WD+ +G+ + T V P T SV+W +D G+
Sbjct: 313 VISW-SRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVT--SVEWHPQDSGVF 369
Query: 192 CTSCRDKRVR------IIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGK 233
S D ++ +P G V A+ P P + +FV +G+
Sbjct: 370 AASGADHQITQWDLAVERDPEAGDVEAD---PGLADLPQQLLFVHQGE 414
Score = 48.5 bits (114), Expect = 1e-05
Identities = 34/132 (25%), Positives = 52/132 (39%), Gaps = 7/132 (5%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GH + W P + +G + +W DGG + P V GHT+ V +
Sbjct: 212 GHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFV---GHTRSVEDLQ 268
Query: 139 WHTTAQNVLLSAGCDNVIMVWDVGTG---AAMLTLGPEVHPDTIYSVDWSRDGGLICTSC 195
W T V S D I +WD+ A MLT H + + WSR + +
Sbjct: 269 WSPTENTVFASCSADASIRIWDIRAAPSKACMLTTA-TAHDGDVNVISWSRREPFLLSGG 327
Query: 196 RDKRVRIIEPRK 207
D ++I + R+
Sbjct: 328 DDGALKIWDLRQ 339
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 62.0 bits (149), Expect = 1e-09
Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 10/133 (7%)
Query: 71 DKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGH 130
D+ GHTA V + W P + ++ SGS+D TV +W+ + L GH
Sbjct: 532 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC-------INILNGH 584
Query: 131 TKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGL 190
T V + W+T +L+S D I VWD G + T+ H +Y +
Sbjct: 585 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYD--HGADVYGLTCHPSRPF 642
Query: 191 ICTSC-RDKRVRI 202
SC RD VR+
Sbjct: 643 TMASCSRDSTVRL 655
Score = 56.2 bits (134), Expect = 6e-08
Identities = 54/220 (24%), Positives = 88/220 (40%), Gaps = 18/220 (8%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H A V W +N ++IA+G ED V V+ + +P+ GHT +V V W
Sbjct: 496 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSS-----DQPLKVFSGHTAKVFHVKW 550
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRD-GGLICTSCRDK 198
+ +L S D + +WD A + L P + + W+ + L+ + D
Sbjct: 551 SPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAP--VRGLMWNTEIPYLLISGSWDY 608
Query: 199 RVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVALWDTKHLEEP 258
+++ + R+GT V D ++ V + + T S + V LW L P
Sbjct: 609 TIKVWDTREGTCV---DTVYDHGADVYGLTCHPSRPFTMA-SCSRDSTVRLWSLTALVTP 664
Query: 259 LSLQELDTSS-----GVLLPFFDPDTNIVYLCGKGDSSIR 293
+ + L S G +P T + LCGK IR
Sbjct: 665 VQINILADRSWEEIIGNTDYAIEPGTPPL-LCGKVSRDIR 703
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRV-GIVA 138
H + I+WCPHN ++ ASGS D V++W + + + V+ TK + ++
Sbjct: 58 HKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE--------QKVIAKLDSTKGIPASLS 109
Query: 139 WHTTAQNVLLSAGCDNVIMVWDV 161
W A++V+ + +W +
Sbjct: 110 WCWNAEDVVAFVSHRGPLFIWTI 132
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/139 (22%), Positives = 53/139 (38%), Gaps = 8/139 (5%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GH + D + P + N++A+ S D T+ VW+I V T G+ + ++
Sbjct: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI-------NTLTAVYTSPGNEGVIYSLS 419
Query: 139 WHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDK 198
W N + N +W+V G + E + I+ + WS +C
Sbjct: 420 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFN-EHGTNGIFCIAWSHKDSKRIATCSSD 478
Query: 199 RVRIIEPRKGTVVAEKDRP 217
II G V+ + P
Sbjct: 479 GFCIIRTIDGKVLHKYKHP 497
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 62.0 bits (149), Expect = 1e-09
Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 10/133 (7%)
Query: 71 DKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGH 130
D+ GHTA V + W P + ++ SGS+D TV +W+ + L GH
Sbjct: 556 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC-------INILNGH 608
Query: 131 TKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGL 190
T V + W+T +L+S D I VWD G + T+ H +Y +
Sbjct: 609 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYD--HGADVYGLTCHPSRPF 666
Query: 191 ICTSC-RDKRVRI 202
SC RD VR+
Sbjct: 667 TMASCSRDSTVRL 679
Score = 56.2 bits (134), Expect = 6e-08
Identities = 54/220 (24%), Positives = 88/220 (40%), Gaps = 18/220 (8%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H A V W +N ++IA+G ED V V+ + +P+ GHT +V V W
Sbjct: 520 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSS-----DQPLKVFSGHTAKVFHVKW 574
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRD-GGLICTSCRDK 198
+ +L S D + +WD A + L P + + W+ + L+ + D
Sbjct: 575 SPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAP--VRGLMWNTEIPYLLISGSWDY 632
Query: 199 RVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVALWDTKHLEEP 258
+++ + R+GT V D ++ V + + T S + V LW L P
Sbjct: 633 TIKVWDTREGTCV---DTVYDHGADVYGLTCHPSRPFTMA-SCSRDSTVRLWSLTALVTP 688
Query: 259 LSLQELDTSS-----GVLLPFFDPDTNIVYLCGKGDSSIR 293
+ + L S G +P T + LCGK IR
Sbjct: 689 VQINILADRSWEEIIGNTDYAIEPGTPPL-LCGKVSRDIR 727
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRV-GIVA 138
H + I+WCPHN ++ ASGS D V++W + + + V+ TK + ++
Sbjct: 82 HKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE--------QKVIAKLDSTKGIPASLS 133
Query: 139 WHTTAQNVLLSAGCDNVIMVWDV 161
W A++V+ + +W +
Sbjct: 134 WCWNAEDVVAFVSHRGPLFIWTI 156
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/139 (22%), Positives = 53/139 (38%), Gaps = 8/139 (5%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GH + D + P + N++A+ S D T+ VW+I V T G+ + ++
Sbjct: 391 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI-------NTLTAVYTSPGNEGVIYSLS 443
Query: 139 WHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDK 198
W N + N +W+V G + E + I+ + WS +C
Sbjct: 444 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFN-EHGTNGIFCIAWSHKDSKRIATCSSD 502
Query: 199 RVRIIEPRKGTVVAEKDRP 217
II G V+ + P
Sbjct: 503 GFCIIRTIDGKVLHKYKHP 521
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/221 (20%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 17 QPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLG---KTGRVDKN 73
+P + +C D+R+ + + NP + AS + + K G+V
Sbjct: 125 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 184
Query: 74 APTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKR 133
GHTA V D++W ++++ S ++D +M+W+ +P +++ HT
Sbjct: 185 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNN----TSKPSHSVDAHTAE 240
Query: 134 VGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWS-RDGGLIC 192
V ++++ ++ +L + D + +WD+ + E H D I+ V WS + ++
Sbjct: 241 VNCLSFNPYSEFILATGSADKTVALWDL-RNLKLKLHSFESHKDEIFQVQWSPHNETILA 299
Query: 193 TSCRDKRVRIIEPRKGTVVAEKDRPHEG-TRPVRAVFVSEG 232
+S D+R+ + + K + E+ P + P +F+ G
Sbjct: 300 SSGTDRRLNVWDLSK---IGEEQSPEDAEDGPPELLFIHGG 337
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 9/90 (10%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEI--------PDGGLMLPLREPVVTLEGHT 131
H + + W PHN+ ++AS D + VW++ P+ P E + GHT
Sbjct: 281 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGP-PELLFIHGGHT 339
Query: 132 KRVGIVAWHTTAQNVLLSAGCDNVIMVWDV 161
++ +W+ V+ S DN++ VW +
Sbjct: 340 AKISDFSWNPNEPWVICSVSEDNIMQVWQM 369
Score = 35.8 bits (81), Expect = 0.084
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPD 113
GHTA + D +W P+ VI S SED + VW++ +
Sbjct: 337 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAE 371
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/221 (20%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 17 QPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLG---KTGRVDKN 73
+P + +C D+R+ + + NP + AS + + K G+V
Sbjct: 159 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 218
Query: 74 APTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKR 133
GHTA V D++W ++++ S ++D +M+W+ +P +++ HT
Sbjct: 219 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNN----TSKPSHSVDAHTAE 274
Query: 134 VGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWS-RDGGLIC 192
V ++++ ++ +L + D + +WD+ + E H D I+ V WS + ++
Sbjct: 275 VNCLSFNPYSEFILATGSADKTVALWDL-RNLKLKLHSFESHKDEIFQVQWSPHNETILA 333
Query: 193 TSCRDKRVRIIEPRKGTVVAEKDRPHEG-TRPVRAVFVSEG 232
+S D+R+ + + K + E+ P + P +F+ G
Sbjct: 334 SSGTDRRLNVWDLSK---IGEEQSPEDAEDGPPELLFIHGG 371
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 9/90 (10%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEI--------PDGGLMLPLREPVVTLEGHT 131
H + + W PHN+ ++AS D + VW++ P+ P E + GHT
Sbjct: 315 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGP-PELLFIHGGHT 373
Query: 132 KRVGIVAWHTTAQNVLLSAGCDNVIMVWDV 161
++ +W+ V+ S DN++ VW +
Sbjct: 374 AKISDFSWNPNEPWVICSVSEDNIMQVWQM 403
Score = 35.8 bits (81), Expect = 0.084
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPD 113
GHTA + D +W P+ VI S SED + VW++ +
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAE 405
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/221 (20%), Positives = 98/221 (44%), Gaps = 13/221 (5%)
Query: 17 QPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLG---KTGRVDKN 73
+P + +C D+R+ + + NP + AS + + K G+V
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 74 APTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKR 133
GHTA V D++W ++++ S ++D +M+W+ +P +++ HT
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNN----TSKPSHSVDAHTAE 275
Query: 134 VGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWS-RDGGLIC 192
V ++++ ++ +L + D + +WD+ + E H D I+ V WS + ++
Sbjct: 276 VNCLSFNPYSEFILATGSADKTVALWDL-RNLKLKLHSFESHKDEIFQVQWSPHNETILA 334
Query: 193 TSCRDKRVRIIEPRKGTVVAEKDRPHEG-TRPVRAVFVSEG 232
+S D+R+ + + K + E+ P + P +F+ G
Sbjct: 335 SSGTDRRLNVWDLSK---IGEEQSPEDAEDGPPELLFIHGG 372
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 9/90 (10%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEI--------PDGGLMLPLREPVVTLEGHT 131
H + + W PHN+ ++AS D + VW++ P+ P E + GHT
Sbjct: 316 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGP-PELLFIHGGHT 374
Query: 132 KRVGIVAWHTTAQNVLLSAGCDNVIMVWDV 161
++ +W+ V+ S DN++ VW +
Sbjct: 375 AKISDFSWNPNEPWVICSVSEDNIMQVWQM 404
Score = 35.8 bits (81), Expect = 0.084
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPD 113
GHTA + D +W P+ VI S SED + VW++ +
Sbjct: 372 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAE 406
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 59.3 bits (142), Expect = 7e-09
Identities = 47/184 (25%), Positives = 83/184 (45%), Gaps = 28/184 (15%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H+AP LD+ W ++N AS S D + V ++ P+ T +GHT V + W
Sbjct: 307 HSAPALDVDW--QSNNTFASCSTDMCIHVCKLGQD-------RPIKTFQGHTNEVNAIKW 357
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGG---------L 190
T N+L S D + +W + + L + H IY++ WS G +
Sbjct: 358 DPTG-NLLASCSDDMTLKIWSMKQDNCVHDL--QAHNKEIYTIKWSPTGPGTNNPNANLM 414
Query: 191 ICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVAL 249
+ ++ D VR+ + +G + + E PV +V F +G+ L +G ++ V +
Sbjct: 415 LASASFDSTVRLWDVDRGICIHTLTKHQE---PVYSVAFSPDGRYLASG---SFDKCVHI 468
Query: 250 WDTK 253
W+T+
Sbjct: 469 WNTQ 472
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 18/140 (12%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPD----GGLMLPLREPVVTLEG----- 129
GH + V AW P +D ++ASGS D T +W + + G L LR + EG
Sbjct: 167 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLSENSTSGSTQLVLRHCI--REGGQDVP 223
Query: 130 HTKRVGIVAWHTTAQNVLLSAGC-DNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDG 188
K V + W+ ++ LL+ G D +W G TLG H I+++ W++ G
Sbjct: 224 SNKDVTSLDWN--SEGTLLATGSYDGFARIW-TKDGNLASTLGQ--HKGPIFALKWNKKG 278
Query: 189 GLICTSCRDKRVRIIEPRKG 208
I ++ DK I + G
Sbjct: 279 NFILSAGVDKTTIIWDAHTG 298
Score = 39.3 bits (90), Expect = 0.008
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 14/102 (13%)
Query: 113 DGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVG----TGAAML 168
DG + +P + VV L GH V I AW+ + ++L S D+ +W++ +G+ L
Sbjct: 152 DGDVEIPPNKAVV-LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLSENSTSGSTQL 209
Query: 169 TL-------GPEVHPDT-IYSVDWSRDGGLICTSCRDKRVRI 202
L G +V + + S+DW+ +G L+ T D RI
Sbjct: 210 VLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARI 251
Score = 30.0 bits (66), Expect = 4.6
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ H PV +A+ P + +ASGS D V +W G L+ R T +
Sbjct: 437 TLTKHQEPVYSVAFSP-DGRYLASGSFDKCVHIWNTQTGALVHSYR--------GTGGIF 487
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDV 161
V W+ V SA D + V D+
Sbjct: 488 EVCWNAAGDKVGASAS-DGSVCVLDL 512
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 59.3 bits (142), Expect = 7e-09
Identities = 39/130 (30%), Positives = 62/130 (47%), Gaps = 11/130 (8%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GHT + D + P D +A+ S D TV +W++ G +L T EGH++ V
Sbjct: 392 GHTDWLSDCCFHPSGDK-LATSSGDTTVKLWDLCKGDCIL-------TFEGHSRAVWSCT 443
Query: 139 WHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDK 198
WH+ N + S+ D +WDV + TL H D++ S+++ + TS DK
Sbjct: 444 WHSCG-NFVASSSLDKTSKIWDVNSERCRCTL--YGHTDSVNSIEFFPFSNTLLTSSADK 500
Query: 199 RVRIIEPRKG 208
+ I + R G
Sbjct: 501 TLSIWDARTG 510
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 57.8 bits (138), Expect = 2e-08
Identities = 35/134 (26%), Positives = 64/134 (47%), Gaps = 8/134 (5%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H A +L WC +N+N++ +G+ DC++ W++ + +R+PV L GHT + V +
Sbjct: 197 HQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRN------VRQPVFELLGHTYAIRRVKF 250
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCR-DK 198
+VL S D + W+ ++L E H + +D+S C D+
Sbjct: 251 SPFHASVLASCSYDFTVRFWNFSKPDSLLET-VEHHTEFTCGLDFSLQSPTQVADCSWDE 309
Query: 199 RVRIIEPRKGTVVA 212
++I +P T+ A
Sbjct: 310 TIKIYDPACLTIPA 323
Score = 48.5 bits (114), Expect = 1e-05
Identities = 53/281 (18%), Positives = 113/281 (40%), Gaps = 39/281 (13%)
Query: 84 VLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW-HTT 142
+ D+ W +N++V+ + S D ++ +W+ P+ + H + V V W T
Sbjct: 70 LFDVTWSENNEHVLITCSGDGSLQLWDTAKAA------GPLQVYKEHAQEVYSVDWSQTR 123
Query: 143 AQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWS-RDGGLICTSCRDKRVR 201
+ +++S D + +WD G ++ T H IYS WS G ++ D+ +R
Sbjct: 124 GEQLVVSGSWDQTVKLWDPTVGKSLCTF--RGHESIIYSTIWSPHIPGCFASASGDQTLR 181
Query: 202 IIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVAL---------WDT 252
I + + G R V + + +IL+ + + +E + WD
Sbjct: 182 IWDVKAA-----------GVRIV--IPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDL 228
Query: 253 KHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSS 312
+++ +P+ + L + + F P V D ++R++ + L + +
Sbjct: 229 RNVRQPV-FELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHT- 286
Query: 313 KESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVP 353
E G+ + + +V C K++ +P +T+P
Sbjct: 287 -EFTCGLDFSLQSPTQVADCSWDETIKIY----DPACLTIP 322
Score = 29.6 bits (65), Expect = 6.0
Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 6/82 (7%)
Query: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVA 138
GHT + + + P + +V+AS S D TV W +L T+E HT+ +
Sbjct: 240 GHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLE------TVEHHTEFTCGLD 293
Query: 139 WHTTAQNVLLSAGCDNVIMVWD 160
+ + + D I ++D
Sbjct: 294 FSLQSPTQVADCSWDETIKIYD 315
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 57.8 bits (138), Expect = 2e-08
Identities = 49/184 (26%), Positives = 80/184 (43%), Gaps = 28/184 (15%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H+AP LD+ W N+ AS S D + V L PV T +GHT V + W
Sbjct: 317 HSAPALDVDW--QNNMTFASCSTDMCIHVCR-------LGCDHPVKTFQGHTNEVNAIKW 367
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGG---------L 190
+ +L S D + +W + A + L + H IY++ WS G +
Sbjct: 368 DPSGM-LLASCSDDMTLKIWSMKQDACVHDL--QAHSKEIYTIKWSPTGPATSNPNSSIM 424
Query: 191 ICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVAL 249
+ ++ D VR+ + +G + E PV +V F +GK L +G ++ V +
Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMKHQE---PVYSVAFSPDGKYLASG---SFDKYVHI 478
Query: 250 WDTK 253
W+T+
Sbjct: 479 WNTQ 482
Score = 38.5 bits (88), Expect = 0.013
Identities = 38/162 (23%), Positives = 56/162 (34%), Gaps = 52/162 (32%)
Query: 74 APTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWE-----------------IPDGGL 116
A + GH + V AW P +D ++ASGS D T +W I +GG
Sbjct: 172 ATVLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGH 230
Query: 117 MLPLREPVVTLEG-------------------------------HTKRVGIVAWHTTAQN 145
+P + V +L+ H + + W+ N
Sbjct: 231 DVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKG-N 289
Query: 146 VLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRD 187
+LSAG D ++WD TG A H VDW +
Sbjct: 290 YVLSAGVDKTTIIWDAHTGEAKQQF--PFHSAPALDVDWQNN 329
Score = 35.8 bits (81), Expect = 0.084
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 14/102 (13%)
Query: 113 DGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGT----GAAML 168
DG + +P + V L GH V I AW+ + ++L S D+ +W++ G+ L
Sbjct: 162 DGDVEIPPNKATV-LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQL 219
Query: 169 TL-------GPEVHPDT-IYSVDWSRDGGLICTSCRDKRVRI 202
L G +V + + S+DW+ DG L+ D RI
Sbjct: 220 VLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARI 261
Score = 29.3 bits (64), Expect = 7.9
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 10/86 (11%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ H PV +A+ P + +ASGS D V +W G L V + +G T +
Sbjct: 447 TLMKHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNTQSGSL-------VHSYQG-TGGIF 497
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDV 161
V W+ V SA D + V D+
Sbjct: 498 EVCWNARGDKVGASAS-DGSVCVLDL 522
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 57.8 bits (138), Expect = 2e-08
Identities = 49/184 (26%), Positives = 80/184 (43%), Gaps = 28/184 (15%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H+AP LD+ W N+ AS S D + V L PV T +GHT V + W
Sbjct: 317 HSAPALDVDW--QNNMTFASCSTDMCIHVCR-------LGCDHPVKTFQGHTNEVNAIKW 367
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGG---------L 190
+ +L S D + +W + A + L + H IY++ WS G +
Sbjct: 368 DPSGM-LLASCSDDMTLKIWSMKQDACVHDL--QAHSKEIYTIKWSPTGPATSNPNSSIM 424
Query: 191 ICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVAL 249
+ ++ D VR+ + +G + E PV +V F +GK L +G ++ V +
Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMKHQE---PVYSVAFSPDGKYLASG---SFDKYVHI 478
Query: 250 WDTK 253
W+T+
Sbjct: 479 WNTQ 482
Score = 38.5 bits (88), Expect = 0.013
Identities = 38/162 (23%), Positives = 56/162 (34%), Gaps = 52/162 (32%)
Query: 74 APTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWE-----------------IPDGGL 116
A + GH + V AW P +D ++ASGS D T +W I +GG
Sbjct: 172 ATVLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGH 230
Query: 117 MLPLREPVVTLEG-------------------------------HTKRVGIVAWHTTAQN 145
+P + V +L+ H + + W+ N
Sbjct: 231 DVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKG-N 289
Query: 146 VLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRD 187
+LSAG D ++WD TG A H VDW +
Sbjct: 290 YVLSAGVDKTTIIWDAHTGEAKQQF--PFHSAPALDVDWQNN 329
Score = 35.8 bits (81), Expect = 0.084
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 14/102 (13%)
Query: 113 DGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGT----GAAML 168
DG + +P + V L GH V I AW+ + ++L S D+ +W++ G+ L
Sbjct: 162 DGDVEIPPNKATV-LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQL 219
Query: 169 TL-------GPEVHPDT-IYSVDWSRDGGLICTSCRDKRVRI 202
L G +V + + S+DW+ DG L+ D RI
Sbjct: 220 VLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARI 261
Score = 29.3 bits (64), Expect = 7.9
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 10/86 (11%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ H PV +A+ P + +ASGS D V +W G L V + +G T +
Sbjct: 447 TLMKHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNTQSGSL-------VHSYQG-TGGIF 497
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDV 161
V W+ V SA D + V D+
Sbjct: 498 EVCWNARGDKVGASAS-DGSVCVLDL 522
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 57.8 bits (138), Expect = 2e-08
Identities = 49/184 (26%), Positives = 80/184 (43%), Gaps = 28/184 (15%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H+AP LD+ W N+ AS S D + V L PV T +GHT V + W
Sbjct: 317 HSAPALDVDW--QNNMTFASCSTDMCIHVCR-------LGCDHPVKTFQGHTNEVNAIKW 367
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGG---------L 190
+ +L S D + +W + A + L + H IY++ WS G +
Sbjct: 368 DPSGM-LLASCSDDMTLKIWSMKQDACVHDL--QAHSKEIYTIKWSPTGPATSNPNSSIM 424
Query: 191 ICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVAL 249
+ ++ D VR+ + +G + E PV +V F +GK L +G ++ V +
Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMKHQE---PVYSVAFSPDGKYLASG---SFDKYVHI 478
Query: 250 WDTK 253
W+T+
Sbjct: 479 WNTQ 482
Score = 38.5 bits (88), Expect = 0.013
Identities = 38/162 (23%), Positives = 56/162 (34%), Gaps = 52/162 (32%)
Query: 74 APTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWE-----------------IPDGGL 116
A + GH + V AW P +D ++ASGS D T +W I +GG
Sbjct: 172 ATVLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGH 230
Query: 117 MLPLREPVVTLEG-------------------------------HTKRVGIVAWHTTAQN 145
+P + V +L+ H + + W+ N
Sbjct: 231 DVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKG-N 289
Query: 146 VLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRD 187
+LSAG D ++WD TG A H VDW +
Sbjct: 290 YVLSAGVDKTTIIWDAHTGEAKQQF--PFHSAPALDVDWQNN 329
Score = 35.8 bits (81), Expect = 0.084
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 14/102 (13%)
Query: 113 DGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGT----GAAML 168
DG + +P + V L GH V I AW+ + ++L S D+ +W++ G+ L
Sbjct: 162 DGDVEIPPNKATV-LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQL 219
Query: 169 TL-------GPEVHPDT-IYSVDWSRDGGLICTSCRDKRVRI 202
L G +V + + S+DW+ DG L+ D RI
Sbjct: 220 VLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARI 261
Score = 29.3 bits (64), Expect = 7.9
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 10/86 (11%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ H PV +A+ P + +ASGS D V +W G L V + +G T +
Sbjct: 447 TLMKHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNTQSGSL-------VHSYQG-TGGIF 497
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDV 161
V W+ V SA D + V D+
Sbjct: 498 EVCWNARGDKVGASAS-DGSVCVLDL 522
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 56.2 bits (134), Expect = 6e-08
Identities = 48/184 (26%), Positives = 79/184 (42%), Gaps = 28/184 (15%)
Query: 80 HTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAW 139
H+AP LD+ W N+ AS S D + V L PV T +GHT V + W
Sbjct: 319 HSAPALDVDW--QNNTTFASCSTDMCIHVCR-------LGCDRPVKTFQGHTNEVNAIKW 369
Query: 140 HTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGG---------L 190
+ +L S D + +W + + L + H IY++ WS G +
Sbjct: 370 DPSGM-LLASCSDDMTLKIWSMKQEVCIHDL--QAHNKEIYTIKWSPTGPATSNPNSNIM 426
Query: 191 ICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAV-FVSEGKILTTGFSRMSERQVAL 249
+ ++ D VR+ + +G + E PV +V F +GK L +G ++ V +
Sbjct: 427 LASASFDSTVRLWDIERGVCTHTLTKHQE---PVYSVAFSPDGKYLASG---SFDKCVHI 480
Query: 250 WDTK 253
W+T+
Sbjct: 481 WNTQ 484
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/158 (27%), Positives = 60/158 (37%), Gaps = 23/158 (14%)
Query: 40 CAVNPKFVALICEASGGGAFLVLPL------GKTGRVDKNAPTVCGHTAP----VLDIAW 89
CA NP L+ SG + L G T V ++ GH P V + W
Sbjct: 187 CAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDW 245
Query: 90 CPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLS 149
N ++A+GS D +W DG L TL H + + W+ N +LS
Sbjct: 246 NT-NGTLLATGSYDGFARIWT-EDGNL-------ASTLGQHKGPIFALKWNRKG-NYILS 295
Query: 150 AGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRD 187
AG D ++WD TG A H VDW +
Sbjct: 296 AGVDKTTIIWDAHTGEAKQQF--PFHSAPALDVDWQNN 331
Score = 35.8 bits (81), Expect = 0.084
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 14/102 (13%)
Query: 113 DGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGT----GAAML 168
DG + +P + V L GH V I AW+ + ++L S D+ +W++ G+ L
Sbjct: 164 DGEVEIPSSKATV-LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQL 221
Query: 169 TL-------GPEVHPDT-IYSVDWSRDGGLICTSCRDKRVRI 202
L G +V + + S+DW+ +G L+ T D RI
Sbjct: 222 VLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARI 263
Score = 30.0 bits (66), Expect = 4.6
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 76 TVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVG 135
T+ H PV +A+ P + +ASGS D V +W G L+ R T +
Sbjct: 449 TLTKHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQSGNLVHSYR--------GTGGIF 499
Query: 136 IVAWHTTAQNVLLSAGCDNVIMVWDV 161
V W+ V SA D + V D+
Sbjct: 500 EVCWNARGDKVGASAS-DGSVCVLDL 524
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,365,276
Number of Sequences: 37866
Number of extensions: 945087
Number of successful extensions: 4683
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 177
Number of HSP's that attempted gapping in prelim test: 3890
Number of HSP's gapped (non-prelim): 673
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.