Search of human proteins with 58331179

Search of human proteins with 58331179

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58331179 KIAA1688 protein [Homo sapiens]
         (1114 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58331179 KIAA1688 protein [Homo sapiens]                          2279   0.0  
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...    91   8e-18
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    91   8e-18
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...    89   3e-17
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             87   1e-16
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...    84   7e-16
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...    84   7e-16
gi|122937512 myosin VIIB [Homo sapiens]                                67   1e-10
gi|188497642 ARHGAP15 [Homo sapiens]                                   66   2e-10
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]            65   3e-10
gi|156119615 myosin IXA [Homo sapiens]                                 65   5e-10
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        64   8e-10
gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo sap...    63   1e-09
gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo sa...    63   1e-09
gi|118402590 myosin XV [Homo sapiens]                                  62   2e-09
gi|23510413 sorting nexin 26 [Homo sapiens]                            62   3e-09
gi|56119110 family with sequence similarity 13, member A1 isofor...    62   4e-09
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]    61   7e-09
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]     61   7e-09
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            61   7e-09
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       60   9e-09
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        60   9e-09
gi|54860079 nadrin isoform 1 [Homo sapiens]                            60   1e-08
gi|54860105 nadrin isoform 2 [Homo sapiens]                            60   1e-08
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]              60   2e-08
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...    60   2e-08
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...    60   2e-08
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]                59   2e-08
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi...    59   2e-08
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...    59   2e-08

>gi|58331179 KIAA1688 protein [Homo sapiens]
          Length = 1114

 Score = 2279 bits (5907), Expect = 0.0
 Identities = 1114/1114 (100%), Positives = 1114/1114 (100%)

Query: 1    MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR 60
            MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
Sbjct: 1    MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR 60

Query: 61   IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA 120
            IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
Sbjct: 61   IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA 120

Query: 121  ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE 180
            ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
Sbjct: 121  ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE 180

Query: 181  KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV 240
            KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
Sbjct: 181  KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV 240

Query: 241  RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ 300
            RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
Sbjct: 241  RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ 300

Query: 301  PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN 360
            PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
Sbjct: 301  PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN 360

Query: 361  KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP 420
            KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
Sbjct: 361  KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP 420

Query: 421  NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD 480
            NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
Sbjct: 421  NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD 480

Query: 481  TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE 540
            TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
Sbjct: 481  TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE 540

Query: 541  GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV 600
            GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
Sbjct: 541  GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV 600

Query: 601  RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC 660
            RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
Sbjct: 601  RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC 660

Query: 661  AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML 720
            AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
Sbjct: 661  AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML 720

Query: 721  AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL 780
            AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
Sbjct: 721  AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL 780

Query: 781  RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK 840
            RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
Sbjct: 781  RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK 840

Query: 841  VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK 900
            VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK
Sbjct: 841  VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK 900

Query: 901  PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG 960
            PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
Sbjct: 901  PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG 960

Query: 961  IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH 1020
            IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
Sbjct: 961  IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH 1020

Query: 1021 YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ 1080
            YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
Sbjct: 1021 YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ 1080

Query: 1081 SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL 1114
            SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
Sbjct: 1081 SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL 1114


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
            sapiens]
          Length = 653

 Score = 90.5 bits (223), Expect = 8e-18
 Identities = 75/217 (34%), Positives = 106/217 (48%), Gaps = 14/217 (6%)

Query: 903  VEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIF 962
            V+ IR      F   +FG  L++ +  ++ RY  R  P +  +  +  +   G + EG+F
Sbjct: 22   VKSIRRVIWGPFGGGIFGQKLEDTVRYEK-RYGNRLAPMLVEQCVD-FIRQRGLKEEGLF 79

Query: 963  RVPGDIDEVNALKLQVDQWKVPT--GLEDPHVPASLLKLWYRELEEPLIPHEFYEQCI-- 1018
            R+PG  + V  L+   D  + P+     D H  ASLLKL+ REL EP+IP+  YE  +  
Sbjct: 80   RLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSC 139

Query: 1019 AHYDSPEAAVAV------VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVM 1072
            A   S E    V      V +LP +N  +L Y+ RFL   VQ  +  V KM V NLA V 
Sbjct: 140  AKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDE-VQSYS-GVNKMSVQNLATVF 197

Query: 1073 APNCLRCQSDDPRVIFENTRKEMSFLRVLIQHLDTSF 1109
             PN LR + +DP  I E T      + V+I   D  F
Sbjct: 198  GPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 234


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
            sapiens]
          Length = 748

 Score = 90.5 bits (223), Expect = 8e-18
 Identities = 75/217 (34%), Positives = 106/217 (48%), Gaps = 14/217 (6%)

Query: 903  VEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIF 962
            V+ IR      F   +FG  L++ +  ++ RY  R  P +  +  +  +   G + EG+F
Sbjct: 117  VKSIRRVIWGPFGGGIFGQKLEDTVRYEK-RYGNRLAPMLVEQCVD-FIRQRGLKEEGLF 174

Query: 963  RVPGDIDEVNALKLQVDQWKVPT--GLEDPHVPASLLKLWYRELEEPLIPHEFYEQCI-- 1018
            R+PG  + V  L+   D  + P+     D H  ASLLKL+ REL EP+IP+  YE  +  
Sbjct: 175  RLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSC 234

Query: 1019 AHYDSPEAAVAV------VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVM 1072
            A   S E    V      V +LP +N  +L Y+ RFL   VQ  +  V KM V NLA V 
Sbjct: 235  AKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDE-VQSYS-GVNKMSVQNLATVF 292

Query: 1073 APNCLRCQSDDPRVIFENTRKEMSFLRVLIQHLDTSF 1109
             PN LR + +DP  I E T      + V+I   D  F
Sbjct: 293  GPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 329


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
            sapiens]
          Length = 655

 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 72/206 (34%), Positives = 102/206 (49%), Gaps = 14/206 (6%)

Query: 914  FSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNA 973
            F   +FG  L++ +  ++ RY  R  P +  +  +  +   G + EG+FR+PG  + V  
Sbjct: 35   FRKGIFGQKLEDTVRYEK-RYGNRLAPMLVEQCVD-FIRQRGLKEEGLFRLPGQANLVKE 92

Query: 974  LKLQVDQWKVPT--GLEDPHVPASLLKLWYRELEEPLIPHEFYEQCI--AHYDSPEAAVA 1029
            L+   D  + P+     D H  ASLLKL+ REL EP+IP+  YE  +  A   S E    
Sbjct: 93   LQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG 152

Query: 1030 V------VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDD 1083
            V      V +LP +N  +L Y+ RFL   VQ  +  V KM V NLA V  PN LR + +D
Sbjct: 153  VKELAKQVKSLPVVNYNLLKYICRFLDE-VQSYS-GVNKMSVQNLATVFGPNILRPKVED 210

Query: 1084 PRVIFENTRKEMSFLRVLIQHLDTSF 1109
            P  I E T      + V+I   D  F
Sbjct: 211  PLTIMEGTVVVQQLMSVMISKHDCLF 236


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 71/211 (33%), Positives = 101/211 (47%), Gaps = 14/211 (6%)

Query: 903  VEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIF 962
            V+ IR    A     +FG  L+E +  +R +Y  R  P +  +  + +    G   EG+F
Sbjct: 137  VQAIRRVIWAPLGGGIFGQRLEETVHHER-KYGPRLAPLLVEQCVDFIRE-RGLTEEGLF 194

Query: 963  RVPGDIDEVNALKLQVDQWKVPT--GLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIA- 1019
            R+PG  + V  L+   D  + P      D H  ASLLKL+ REL EP++P   YE  ++ 
Sbjct: 195  RMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSC 254

Query: 1020 ----HYDSPEAAVAV---VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVM 1072
                  D  E  + +   V  LP+ N  +L Y+ +FL      +NV   KM V NLA V 
Sbjct: 255  AQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNV--NKMSVQNLATVF 312

Query: 1073 APNCLRCQSDDPRVIFENTRKEMSFLRVLIQ 1103
             PN LR Q +DP  I E T      + VLI+
Sbjct: 313  GPNILRPQVEDPVTIMEGTSLVQHLMTVLIR 343


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sapiens]
          Length = 645

 Score = 84.0 bits (206), Expect = 7e-16
 Identities = 64/202 (31%), Positives = 102/202 (50%), Gaps = 14/202 (6%)

Query: 918  MFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQ 977
            +FG  L E +  + +++    +P +  + +E +L  +G   EGIFR+PG  + V  L+  
Sbjct: 156  VFGQRLDETVAYE-QKFGPHLVPILVEKCAEFILE-HGRNEEGIFRLPGQDNLVKQLRDA 213

Query: 978  VDQWKVPTGLEDP--HVPASLLKLWYRELEEPLIPHEFYEQCI-----AHYDSPEAAVAV 1030
             D  + P+   D   H  ASLLKL+ R+L EP++P   YE  +      + D  +A   +
Sbjct: 214  FDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQEL 273

Query: 1031 VHAL---PRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVI 1087
            +  L   PR N  +L Y+ RFL       N AV KM V NLA V+  N +R + +DP VI
Sbjct: 274  MKQLSILPRDNYSLLSYICRFLHEI--QLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVI 331

Query: 1088 FENTRKEMSFLRVLIQHLDTSF 1109
               T +    + ++I+  +  F
Sbjct: 332  MRGTPQIQRVMTMMIRDHEVLF 353


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapiens]
          Length = 638

 Score = 84.0 bits (206), Expect = 7e-16
 Identities = 64/202 (31%), Positives = 102/202 (50%), Gaps = 14/202 (6%)

Query: 918  MFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQ 977
            +FG  L E +  + +++    +P +  + +E +L  +G   EGIFR+PG  + V  L+  
Sbjct: 149  VFGQRLDETVAYE-QKFGPHLVPILVEKCAEFILE-HGRNEEGIFRLPGQDNLVKQLRDA 206

Query: 978  VDQWKVPTGLEDP--HVPASLLKLWYRELEEPLIPHEFYEQCI-----AHYDSPEAAVAV 1030
             D  + P+   D   H  ASLLKL+ R+L EP++P   YE  +      + D  +A   +
Sbjct: 207  FDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQEL 266

Query: 1031 VHAL---PRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVI 1087
            +  L   PR N  +L Y+ RFL       N AV KM V NLA V+  N +R + +DP VI
Sbjct: 267  MKQLSILPRDNYSLLSYICRFLHEI--QLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVI 324

Query: 1088 FENTRKEMSFLRVLIQHLDTSF 1109
               T +    + ++I+  +  F
Sbjct: 325  MRGTPQIQRVMTMMIRDHEVLF 346


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 27/50 (54%), Positives = 38/50 (76%)

Query: 780  LRDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYI 829
            LRDE+Y Q+C+Q +ENF+  SLARGW L+++CL  FPP+ +F  YL  +I
Sbjct: 1106 LRDEIYCQICKQLSENFKTSSLARGWILLSLCLGCFPPSERFMKYLLNFI 1155



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 37/143 (25%), Positives = 72/143 (50%), Gaps = 4/143 (2%)

Query: 718  NMLAWSSESIKKPMI--VTSDRHVKKEACELFKLIQMYMGD--RRAKADPLHVALEVATK 773
            ++ A+S E +++P++  V ++  +   AC++F  I  YMGD   R     L +  ++ T 
Sbjct: 1640 HLWAYSCEPLRQPLLKRVHANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTL 1699

Query: 774  GWSVQGLRDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHM 833
                  L+DE+Y Q+ +Q T N    S  RGW+L+ +C   FPP+     + + +I    
Sbjct: 1700 ALQHPALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFIDTRR 1759

Query: 834  DPVNDTKVTQHIKELLERNTKKK 856
              +     ++ I+++L    +K+
Sbjct: 1760 GKLLAPDCSRRIQKVLRTGPRKQ 1782


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 20/194 (10%)

Query: 899  KKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQT 958
            ++P+++ ++  +  +    +FGS L +V   +RE      +PW   +  E V    G   
Sbjct: 261  RRPSLKTLQ--EKGLIKDQIFGSHLHKVC--EREN---STVPWFVKQCIEAV-EKRGLDV 312

Query: 959  EGIFRVPGDIDEVNALKLQVDQWKV----PTGLEDPHVPASLLKLWYRELEEPLIPHEFY 1014
            +GI+RV G++  +  L+  V+Q +      +  ED HV    LK+++REL EPL P+ F+
Sbjct: 313  DGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFF 372

Query: 1015 EQCIAHYDSP------EAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNL 1068
            EQ +            EA  ++V  LP  NR  +  L   L   V  A  +   M   +L
Sbjct: 373  EQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIV--AKASKNLMSTQSL 430

Query: 1069 AMVMAPNCLRCQSD 1082
             +V  P  LR +++
Sbjct: 431  GIVFGPTLLRAENE 444


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 13/174 (7%)

Query: 918  MFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNAL--K 975
            +F   L  ++   + + P  ++P +  +L   +    G +TEG+ R+PG    +  L  +
Sbjct: 321  LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEE-RGLETEGLLRIPGAAIRIKNLCQE 379

Query: 976  LQVDQWKVPTGLED--PHVPASLLKLWYRELEEPLIPHEFYEQCIAHYDSP------EAA 1027
            L+   ++     E    H  ASLLKL+ REL +PL+  E+ +   A  + P      +A 
Sbjct: 380  LEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQAL 439

Query: 1028 VAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQS 1081
              +V  LP  NR  L  L+ FLQ  +   N    KM V N+AMVMAPN   C +
Sbjct: 440  NLLVILLPDANRDTLKALLEFLQRVID--NKEKNKMTVMNVAMVMAPNLFMCHA 491


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 67/266 (25%), Positives = 118/266 (44%), Gaps = 21/266 (7%)

Query: 855  KKSKLRKKPKPYVEEPDG-------VAISTYAKYCYHKL----QKAALTGAKKGLKKPNV 903
            ++ K RKK    VEE +G        +I TY +YC   +    + +     K    K   
Sbjct: 1982 ERKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCC 2041

Query: 904  EEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFR 963
             +     +  + P +  S+ Q  + + R    +R +P V  +L    + ++G  TEGI+R
Sbjct: 2042 LKTTAKCSKKYDPEL--SSRQFGVELSRLTSEDRTVPLVVEKLI-NYIEMHGLYTEGIYR 2098

Query: 964  VPGDIDEVNALKLQVDQWKVPTGLED--PHVPASLLKLWYRELEEPLIPHEFYEQ---CI 1018
              G  +++  L+  +D       L+D   HV AS+ K W R+L  PL+  E YE+    +
Sbjct: 2099 KSGSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAM 2158

Query: 1019 AHYDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPA-NVAVTKMDVSNLAMVMAPNCL 1077
               +  E    V   + +++R  L  L R +   V+ A      +M  + LA+V AP  L
Sbjct: 2159 GLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCIL 2218

Query: 1078 RC-QSDDPRVIFENTRKEMSFLRVLI 1102
            RC  + DP    ++  K  + + +++
Sbjct: 2219 RCPDTTDPLQSVQDISKTTTCVELIV 2244


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 12/165 (7%)

Query: 955  GDQTEGIFRVPGDIDEVNALKLQVDQWKVPTG--LEDPHVPASLLKLWYRELEEPLIPHE 1012
            G Q EG+FRV     ++  LK  +D   V       DPH  A  LK + REL EPL+  E
Sbjct: 283  GMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFE 342

Query: 1013 FYEQCIAHYDSPE------AAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVS 1066
             Y++ I   +  E      A       LP+ N   + YLI+FL    +  +  V KM  S
Sbjct: 343  LYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQD--VNKMTPS 400

Query: 1067 NLAMVMAPNCL--RCQSDDPRVIFENTRKEMSFLRVLIQHLDTSF 1109
            N+A+V+ PN L  + + +   ++   + + +  +  +IQH D  F
Sbjct: 401  NMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQHADWFF 445


>gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo sapiens]
          Length = 1023

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 16/157 (10%)

Query: 958  TEGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYE-- 1015
            TEG+FR  G +  + ALK +VD  +       P   A LLK ++REL EP++P + +E  
Sbjct: 82   TEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEAL 141

Query: 1016 ---QCIAHYDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAV----TKMDVSNL 1068
               Q +   +  +A + +   L      VL Y   FL+      NV++     KMD SNL
Sbjct: 142  LKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLR------NVSLRSSENKMDSSNL 195

Query: 1069 AMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLIQHL 1105
            A++ APN L+  S+    +  NT K++     ++Q L
Sbjct: 196  AVIFAPNLLQ-TSEGHEKMSSNTEKKLRLQAAVVQTL 231


>gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo
            sapiens]
          Length = 501

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 16/157 (10%)

Query: 958  TEGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYE-- 1015
            TEG+FR  G +  + ALK +VD  +       P   A LLK ++REL EP++P + +E  
Sbjct: 82   TEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEAL 141

Query: 1016 ---QCIAHYDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAV----TKMDVSNL 1068
               Q +   +  +A + +   L      VL Y   FL+      NV++     KMD SNL
Sbjct: 142  LKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLR------NVSLRSSENKMDSSNL 195

Query: 1069 AMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLIQHL 1105
            A++ APN L+  S+    +  NT K++     ++Q L
Sbjct: 196  AVIFAPNLLQ-TSEGHEKMSSNTEKKLRLQAAVVQTL 231


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 37/94 (39%), Positives = 49/94 (52%), Gaps = 11/94 (11%)

Query: 742  EACELFKLIQMYMGDRRAKADPLHVALE------VATKGWSVQGLRDELYIQLCRQTTEN 795
            EA  +FKLI  +MGD       LH A E      +  KG +V  LRDE+  QL  Q   N
Sbjct: 2084 EAVSIFKLILRFMGDPH-----LHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHN 2138

Query: 796  FRLESLARGWELMAICLAFFPPTPKFHSYLEGYI 829
                +  RGW L+A CL+ F P+P F+ YL  ++
Sbjct: 2139 HNAHNAERGWLLLAACLSGFAPSPCFNKYLLKFV 2172



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 32/122 (26%), Positives = 60/122 (49%), Gaps = 3/122 (2%)

Query: 711  RRKVSIANMLAWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADP-LHVALE 769
            R   ++ +ML ++   +++ +I  SD  + K A ++F  +  +MGD   K    L V   
Sbjct: 3039 RESRTLEDMLCFTKTPLQESLIELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLDVLCN 3098

Query: 770  VATKGWSVQGLRDELYIQLCRQTTEN--FRLESLARGWELMAICLAFFPPTPKFHSYLEG 827
            +       + +RDE Y Q+ +Q T+N   + +S  RGW L+ I  A+   +   H +L  
Sbjct: 3099 LLKLCGDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTR 3158

Query: 828  YI 829
            ++
Sbjct: 3159 FL 3160


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 59/240 (24%), Positives = 100/240 (41%), Gaps = 25/240 (10%)

Query: 888  KAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLS 947
            +  L G  +   +      R  +  +    +FG  L E +    +  P+        R  
Sbjct: 282  RGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQ------VLRCC 335

Query: 948  EEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVP-----TGLEDPHVPASLLKLWYR 1002
             E +  +G   +GI+R+ G    +  L+ + D  ++P       L+D H  +SL KL++R
Sbjct: 336  SEFIEAHG-VVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFR 394

Query: 1003 ELEEPLIPHEFY---EQCIAHYDSPEAAVA---VVHALPRINRMVLCYLIRFLQVFVQPA 1056
            EL  PL+ ++ Y    + ++     E  V    V+  LP  +   L YL+R L    +  
Sbjct: 395  ELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMAR-- 452

Query: 1057 NVAVTKMDVSNLAMVMAPNCLRCQSDDP-----RVIFENTRKEMSFLRVLIQHLDTSFME 1111
            + A T M   NLA+V APN LR    +         F   R +   +  L+ H+D  F +
Sbjct: 453  HSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVDVLFSD 512


>gi|56119110 family with sequence similarity 13, member A1 isoform a
            [Homo sapiens]
          Length = 1023

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 61/199 (30%), Positives = 96/199 (48%), Gaps = 17/199 (8%)

Query: 887  QKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRL 946
            Q  A    K+ +KK     +   K+  +   +FG +LQE   ++R+   E  +P V   +
Sbjct: 10   QSKAAVRLKEDMKKIVAVPLNEQKDFTYQ-KLFGVSLQE---LERQGLTENGIPAVVWNI 65

Query: 947  SEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPTGL---EDPHVPASLLKLWYRE 1003
             E  L  +G   EG+FRV G++  V  L+L+ +   VP  L    D    ASLLKL+ RE
Sbjct: 66   VE-YLTQHGLTQEGLFRVNGNVKVVEQLRLKFES-GVPVELGKDGDVCSAASLLKLFLRE 123

Query: 1004 LEEPLIPHEFYEQCIAHY-----DSPEAAVA-VVHALPRINRMVLCYLIRFLQVFVQPAN 1057
            L + LI      + I  +     D  E+++  ++  LP  +  +L YL +FL    +  +
Sbjct: 124  LPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKELPDTHYCLLKYLCQFLTKVAK--H 181

Query: 1058 VAVTKMDVSNLAMVMAPNC 1076
                +M+V NLA V  PNC
Sbjct: 182  HVQNRMNVHNLATVFGPNC 200


>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
          Length = 2087

 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 18/167 (10%)

Query: 959  EGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVP-----ASLLKLWYRELEEPLIPHEF 1013
            +GI+R+ G    +  L+ + D   VP   ++P+V       SL KL++REL  PL+ ++ 
Sbjct: 403  DGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQL 462

Query: 1014 YEQ---CIAHYDSPEAAVA---VVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSN 1067
            YE+    ++     E  +    V+  LP  +   L +L+R L +       ++T M   N
Sbjct: 463  YEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLAD--YCSITNMHAKN 520

Query: 1068 LAMVMAPNCLRCQSDDP-----RVIFENTRKEMSFLRVLIQHLDTSF 1109
            LA+V APN LR +  +         F   R +   +  ++ H+D  F
Sbjct: 521  LAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLF 567


>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
          Length = 1738

 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 18/167 (10%)

Query: 959  EGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVP-----ASLLKLWYRELEEPLIPHEF 1013
            +GI+R+ G    +  L+ + D   VP   ++P+V       SL KL++REL  PL+ ++ 
Sbjct: 54   DGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQL 113

Query: 1014 YEQ---CIAHYDSPEAAVA---VVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSN 1067
            YE+    ++     E  +    V+  LP  +   L +L+R L +       ++T M   N
Sbjct: 114  YEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLAD--YCSITNMHAKN 171

Query: 1068 LAMVMAPNCLRCQSDDP-----RVIFENTRKEMSFLRVLIQHLDTSF 1109
            LA+V APN LR +  +         F   R +   +  ++ H+D  F
Sbjct: 172  LAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLF 218


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 26/174 (14%)

Query: 959  EGIFRVPGDIDEVNALKLQVDQWKVP-----TGLEDPHVPASLLKLWYRELEEPLIPHEF 1013
            +GI+R+ G    +  L+ +    + P       L+D H   SL KL++REL  PL+ +E 
Sbjct: 52   DGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYEL 111

Query: 1014 YE---QCIAHYDSPEAAVA----VVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVS 1066
            YE   + ++H    E  +A    V+  LP  +   L YLIR L      +  + T M   
Sbjct: 112  YEKFTEAVSHCPE-EGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFS--SKTNMHAR 168

Query: 1067 NLAMVMAPNCLR--------CQSDDPRVIFENTRKEMSFLRVLIQHLDTSFMEG 1112
            NLA+V APN LR        C  D     F   R +   +  ++ H+D  F  G
Sbjct: 169  NLALVWAPNLLRSKEIEATGCNGD---AAFLAVRVQQVVIEFILNHVDQIFNNG 219


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 70/238 (29%), Positives = 102/238 (42%), Gaps = 34/238 (14%)

Query: 877  TYAKYCYHKLQK-AALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYP 935
            T  K C HK+Q   + T  +KG  +P VE           P  FG  +  +         
Sbjct: 1668 TCHKKCVHKIQSHCSYTYGRKG--EPGVE-----------PGHFGVCVDSLTS------D 1708

Query: 936  ERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALK--LQVDQWKVPTGLEDPHVP 993
            +  +P V  +L E V  ++G  TEG++R  G  +    L+  LQ D   V       H  
Sbjct: 1709 KASVPIVLEKLLEHV-EMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAI 1767

Query: 994  ASLLKLWYRELEEPLIPHEFYEQCIAHYDSPE------AAVAVVHALPRINRMVLCYLIR 1047
              +LK W REL EPL+    Y   +   + PE      A  AV+  LP  N   L  LI 
Sbjct: 1768 TGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIF 1827

Query: 1048 FLQVFVQPANVA-VTKMDVSNLAMVMAPNCLRC-QSDDPRVIFENTRKEMSFLRVLIQ 1103
             L   V+ A +  V +M    LA++ AP  LRC  + DP    ++  K  + + +LI+
Sbjct: 1828 HL---VKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIK 1882


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 70/238 (29%), Positives = 102/238 (42%), Gaps = 34/238 (14%)

Query: 877  TYAKYCYHKLQK-AALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYP 935
            T  K C HK+Q   + T  +KG  +P VE           P  FG  +  +         
Sbjct: 1668 TCHKKCVHKIQSHCSYTYGRKG--EPGVE-----------PGHFGVCVDSLTS------D 1708

Query: 936  ERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALK--LQVDQWKVPTGLEDPHVP 993
            +  +P V  +L E V  ++G  TEG++R  G  +    L+  LQ D   V       H  
Sbjct: 1709 KASVPIVLEKLLEHV-EMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAI 1767

Query: 994  ASLLKLWYRELEEPLIPHEFYEQCIAHYDSPE------AAVAVVHALPRINRMVLCYLIR 1047
              +LK W REL EPL+    Y   +   + PE      A  AV+  LP  N   L  LI 
Sbjct: 1768 TGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIF 1827

Query: 1048 FLQVFVQPANVA-VTKMDVSNLAMVMAPNCLRC-QSDDPRVIFENTRKEMSFLRVLIQ 1103
             L   V+ A +  V +M    LA++ AP  LRC  + DP    ++  K  + + +LI+
Sbjct: 1828 HL---VKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIK 1882


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 12/174 (6%)

Query: 950  VLALNGDQTEGIFRVPGDIDEVNALKLQVD--QWKVPTGLEDPHVPASLLKLWYRELEEP 1007
            +L   G + EG+FR+     ++  LK  +D     +     DPH  A  LK + REL EP
Sbjct: 275  LLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEP 334

Query: 1008 LIPHEFYEQC--IAHYDSPEAAV----AVVHALPRINRMVLCYLIRFLQVFVQPANVAVT 1061
            L+    YE+   +A     +  +         LP  N +   YLI+FL    Q ++  V 
Sbjct: 335  LMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSD--VN 392

Query: 1062 KMDVSNLAMVMAPNCLRCQSDD--PRVIFENTRKEMSFLRVLIQHLDTSFMEGV 1113
            KM  SN+A+V+ PN L  +++     +    +   ++ +  +IQH D  F E V
Sbjct: 393  KMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFPEEV 446



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 70/254 (27%), Positives = 93/254 (36%), Gaps = 61/254 (24%)

Query: 116 PRAS-AESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKE-DSGSSS 173
           P++S AESS G G+  S  G       P   +    + P  A  PA      +  SG + 
Sbjct: 544 PQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQ 603

Query: 174 PPGVFLEKDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYA 233
           P          + + ++A G   H    +LR       R + K A   P        G  
Sbjct: 604 PQAAAGSHQLSMGQPHNAAGPSPH----TLR-------RAVKKPAPAPPK------PGNP 646

Query: 234 PDGPPGVRSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPR 293
           P G PG +S   + SQH PSL   +P+       P R PSP  +    P         P 
Sbjct: 647 PPGHPGGQSSSGT-SQHPPSL---SPKP------PTRSPSPPTQHTGQP---------PG 687

Query: 294 KPSGDSQPSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKP 353
           +PS  SQ S+PR       Y       QAP  + PP               PQ      P
Sbjct: 688 QPSAPSQLSAPRR------YSSSLSPIQAP--NHPP---------------PQPPTQATP 724

Query: 354 RPFLQPNKQGPPSP 367
               +PN QGPP+P
Sbjct: 725 LMHTKPNSQGPPNP 738


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 12/174 (6%)

Query: 950  VLALNGDQTEGIFRVPGDIDEVNALKLQVD--QWKVPTGLEDPHVPASLLKLWYRELEEP 1007
            +L   G + EG+FR+     ++  LK  +D     +     DPH  A  LK + REL EP
Sbjct: 275  LLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEP 334

Query: 1008 LIPHEFYEQC--IAHYDSPEAAV----AVVHALPRINRMVLCYLIRFLQVFVQPANVAVT 1061
            L+    YE+   +A     +  +         LP  N +   YLI+FL    Q ++  V 
Sbjct: 335  LMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSD--VN 392

Query: 1062 KMDVSNLAMVMAPNCLRCQSDD--PRVIFENTRKEMSFLRVLIQHLDTSFMEGV 1113
            KM  SN+A+V+ PN L  +++     +    +   ++ +  +IQH D  F E V
Sbjct: 393  KMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFPEEV 446



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 43/137 (31%), Positives = 53/137 (38%), Gaps = 42/137 (30%)

Query: 231 GYAPDGPPGVRSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLA 290
           G  P G PG +S   + SQH PSL   +P+       P R PSP  +    P        
Sbjct: 566 GNPPPGHPGGQSSSGT-SQHPPSL---SPKP------PTRSPSPPTQHTGQP-------- 607

Query: 291 QPRKPSGDSQPSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPG 350
            P +PS  SQ S+PR       Y       QAP  + PP               PQ    
Sbjct: 608 -PGQPSAPSQLSAPRR------YSSSLSPIQAP--NHPP---------------PQPPTQ 643

Query: 351 RKPRPFLQPNKQGPPSP 367
             P    +PN QGPP+P
Sbjct: 644 ATPLMHTKPNSQGPPNP 660



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 37/145 (25%), Positives = 55/145 (37%), Gaps = 19/145 (13%)

Query: 237 PPGVRSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPS 296
           PP   + +P G   +PS Q  AP    +   P + P+      + P  ++PL+       
Sbjct: 599 PPTQHTGQPPGQPSAPS-QLSAPRRYSSSLSPIQAPNH--PPPQPPTQATPLMHTKPNSQ 655

Query: 297 GDSQPSS--PRYGYEPPLY---------EEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSP 345
           G   P +    +G E P +           PP+  Q P    P    Q  AGG  +   P
Sbjct: 656 GPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAP----QTLAGGNPETAQP 711

Query: 346 QRSPGRKPRPFLQP-NKQGPPSPCQ 369
                 +PRP  +P N+   P P Q
Sbjct: 712 HAGTLPRPRPVPKPRNRPSVPPPPQ 736


>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
          Length = 439

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 17/194 (8%)

Query: 919  FGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQV 978
            FG +LQ +    +E+ PE++   +  R +   L  +   TEGIFR   +   V  ++ + 
Sbjct: 242  FGVSLQHL----QEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKY 297

Query: 979  DQWKVPTGLE---DPHVPASLLKLWYRELEEPLIPHEFYEQCIAHYDSPE-----AAVAV 1030
            +   +P   +   + H+PA +LK + REL EPL+  + Y   +   +  E     A + V
Sbjct: 298  NMG-LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQV 356

Query: 1031 VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFEN 1090
            +  LP  N  VL +L  FL      A+    KM  +NLA+V  PN L   + D  +  + 
Sbjct: 357  LQTLPEENYQVLRFLTAFLVQI--SAHSDQNKMTNTNLAVVFGPNLL--WAKDAAITLKA 412

Query: 1091 TRKEMSFLRVLIQH 1104
                 +F + L+ H
Sbjct: 413  INPINTFTKFLLDH 426


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
            sapiens]
          Length = 521

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 54/211 (25%), Positives = 97/211 (45%), Gaps = 24/211 (11%)

Query: 899  KKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQT 958
            ++P ++ +R  +       +FG AL  +   +R R P     +VQ  +    +   G   
Sbjct: 309  RRPTLQSLR--EKGYIKDQVFGCALAALCERERSRVPR----FVQQCI--RAVEARGLDI 360

Query: 959  EGIFRVPGDIDEVNALKLQVD---QWKVPTGL-EDPHVPASLLKLWYRELEEPLIPHEFY 1014
            +G++R+ G++  +  L+ +VD   +  +  G  ED HV    LKL++REL EPL P   +
Sbjct: 361  DGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHF 420

Query: 1015 EQCIAHYDSPEAAVA------VVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNL 1068
             Q IA     + A        +V +LP  N   L  L + L   ++       +M V ++
Sbjct: 421  RQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGE--QNRMSVQSV 478

Query: 1069 AMVMAPNCLRCQSDDP----RVIFENTRKEM 1095
            A+V  P  LR + ++      ++F+N   E+
Sbjct: 479  AIVFGPTLLRPEVEETSMPMTMVFQNQVVEL 509


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens]
          Length = 548

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 54/211 (25%), Positives = 97/211 (45%), Gaps = 24/211 (11%)

Query: 899  KKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQT 958
            ++P ++ +R  +       +FG AL  +   +R R P     +VQ  +    +   G   
Sbjct: 336  RRPTLQSLR--EKGYIKDQVFGCALAALCERERSRVPR----FVQQCI--RAVEARGLDI 387

Query: 959  EGIFRVPGDIDEVNALKLQVD---QWKVPTGL-EDPHVPASLLKLWYRELEEPLIPHEFY 1014
            +G++R+ G++  +  L+ +VD   +  +  G  ED HV    LKL++REL EPL P   +
Sbjct: 388  DGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHF 447

Query: 1015 EQCIAHYDSPEAAVA------VVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNL 1068
             Q IA     + A        +V +LP  N   L  L + L   ++       +M V ++
Sbjct: 448  RQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGE--QNRMSVQSV 505

Query: 1069 AMVMAPNCLRCQSDDP----RVIFENTRKEM 1095
            A+V  P  LR + ++      ++F+N   E+
Sbjct: 506  AIVFGPTLLRPEVEETSMPMTMVFQNQVVEL 536


>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
          Length = 555

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 50/167 (29%), Positives = 78/167 (46%), Gaps = 16/167 (9%)

Query: 919  FGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQV 978
            FG +LQ +    +       L +  T L E+     G +TEG+FR    +  V  ++   
Sbjct: 315  FGVSLQYLKDKNQGELIPPVLRFTVTYLREK-----GLRTEGLFRRSASVQTVREIQRLY 369

Query: 979  DQWKVPTGLEDP---HVPASLLKLWYRELEEPLIPHEFYEQ-----CIAHYDSPEAAVAV 1030
            +Q K P   +D    H+PA +LK + REL +PL+  + YEQ     C+           +
Sbjct: 370  NQGK-PVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI 428

Query: 1031 VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCL 1077
            + +LP  N +VL YL+ FL    + +     KM+ SNLA V   N +
Sbjct: 429  LRSLPEHNYVVLRYLMGFLHAVSRES--IFNKMNSSNLACVFGLNLI 473


>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapiens]
          Length = 433

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 50/167 (29%), Positives = 78/167 (46%), Gaps = 16/167 (9%)

Query: 919  FGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQV 978
            FG +LQ +    +       L +  T L E+     G +TEG+FR    +  V  ++   
Sbjct: 193  FGVSLQYLKDKNQGELIPPVLRFTVTYLREK-----GLRTEGLFRRSASVQTVREIQRLY 247

Query: 979  DQWKVPTGLEDP---HVPASLLKLWYRELEEPLIPHEFYEQ-----CIAHYDSPEAAVAV 1030
            +Q K P   +D    H+PA +LK + REL +PL+  + YEQ     C+           +
Sbjct: 248  NQGK-PVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI 306

Query: 1031 VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCL 1077
            + +LP  N +VL YL+ FL    + +     KM+ SNLA V   N +
Sbjct: 307  LRSLPEHNYVVLRYLMGFLHAVSRES--IFNKMNSSNLACVFGLNLI 351


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapiens]
          Length = 464

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 50/167 (29%), Positives = 78/167 (46%), Gaps = 16/167 (9%)

Query: 919  FGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQV 978
            FG +LQ +    +       L +  T L E+     G +TEG+FR    +  V  ++   
Sbjct: 224  FGVSLQYLKDKNQGELIPPVLRFTVTYLREK-----GLRTEGLFRRSASVQTVREIQRLY 278

Query: 979  DQWKVPTGLEDP---HVPASLLKLWYRELEEPLIPHEFYEQ-----CIAHYDSPEAAVAV 1030
            +Q K P   +D    H+PA +LK + REL +PL+  + YEQ     C+           +
Sbjct: 279  NQGK-PVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI 337

Query: 1031 VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCL 1077
            + +LP  N +VL YL+ FL    + +     KM+ SNLA V   N +
Sbjct: 338  LRSLPEHNYVVLRYLMGFLHAVSRES--IFNKMNSSNLACVFGLNLI 382


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,830,670
Number of Sequences: 37866
Number of extensions: 2904832
Number of successful extensions: 10739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 450
Number of HSP's that attempted gapping in prelim test: 9564
Number of HSP's gapped (non-prelim): 1521
length of query: 1114
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1001
effective length of database: 13,968,660
effective search space: 13982628660
effective search space used: 13982628660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.