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Search of human proteins with 58197558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58197558 tudor domain containing 6 [Homo sapiens]
(2096 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58197558 tudor domain containing 6 [Homo sapiens] 4229 0.0
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho... 574 e-163
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho... 574 e-163
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho... 574 e-163
gi|38505161 tudor domain containing 1 [Homo sapiens] 134 7e-31
gi|112293287 tudor domain containing 7 [Homo sapiens] 74 1e-12
gi|40255178 tudor domain containing 5 [Homo sapiens] 69 5e-11
gi|94421471 ring finger protein 17 [Homo sapiens] 69 5e-11
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 65 9e-10
gi|145312246 tudor and KH domain containing isoform b [Homo sapi... 65 9e-10
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 65 9e-10
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 65 9e-10
gi|166851804 tudor domain containing 9 [Homo sapiens] 56 3e-07
gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens] 55 9e-07
gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens] 54 1e-06
gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens] 54 1e-06
gi|77404397 staphylococcal nuclease domain containing 1 [Homo sa... 54 2e-06
gi|161016765 tudor domain containing 12 [Homo sapiens] 44 0.001
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens] 39 0.041
gi|110735439 Werner syndrome protein [Homo sapiens] 39 0.053
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 39 0.053
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 38 0.12
gi|197313728 pleckstrin homology-like domain, family B, member 2... 37 0.16
gi|21955172 pleckstrin homology-like domain, family B, member 2 ... 37 0.16
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 35 0.59
gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo... 35 0.59
gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo... 35 0.59
gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo s... 35 0.59
gi|4506869 secreted and transmembrane 1 precursor [Homo sapiens] 35 0.59
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 35 0.77
>gi|58197558 tudor domain containing 6 [Homo sapiens]
Length = 2096
Score = 4229 bits (10968), Expect = 0.0
Identities = 2096/2096 (100%), Positives = 2096/2096 (100%)
Query: 1 MCSTPGMPAPGASLALRVSFVDVHPDVIPVQLWGLVGERRGEYLRLSREIQEAAATRGQW 60
MCSTPGMPAPGASLALRVSFVDVHPDVIPVQLWGLVGERRGEYLRLSREIQEAAATRGQW
Sbjct: 1 MCSTPGMPAPGASLALRVSFVDVHPDVIPVQLWGLVGERRGEYLRLSREIQEAAATRGQW 60
Query: 61 ALGSASASPGELCLVQVGLLWHRCRVVSRQAQESRVFLLDEGRTITAGAGSLAPGRREFF 120
ALGSASASPGELCLVQVGLLWHRCRVVSRQAQESRVFLLDEGRTITAGAGSLAPGRREFF
Sbjct: 61 ALGSASASPGELCLVQVGLLWHRCRVVSRQAQESRVFLLDEGRTITAGAGSLAPGRREFF 120
Query: 121 NLPSEVLGCVLAGLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLV 180
NLPSEVLGCVLAGLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLV
Sbjct: 121 NLPSEVLGCVLAGLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLV 180
Query: 181 LLEVPDVFQQMRELGLARRVPDSLFRSLLERYLTAATASVGSGVPVLSRVPLKQKQPGLD 240
LLEVPDVFQQMRELGLARRVPDSLFRSLLERYLTAATASVGSGVPVLSRVPLKQKQPGLD
Sbjct: 181 LLEVPDVFQQMRELGLARRVPDSLFRSLLERYLTAATASVGSGVPVLSRVPLKQKQPGLD 240
Query: 241 YFYPQLQLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTS 300
YFYPQLQLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTS
Sbjct: 241 YFYPQLQLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTS 300
Query: 301 ATWEEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLR 360
ATWEEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLR
Sbjct: 301 ATWEEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLR 360
Query: 361 YLLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYY 420
YLLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYY
Sbjct: 361 YLLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYY 420
Query: 421 VSLYGEDGINLNRVFGVQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRS 480
VSLYGEDGINLNRVFGVQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRS
Sbjct: 421 VSLYGEDGINLNRVFGVQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRS 480
Query: 481 IRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPD 540
IRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPD
Sbjct: 481 IRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPD 540
Query: 541 DLCCVKWKENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKC 600
DLCCVKWKENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKC
Sbjct: 541 DLCCVKWKENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKC 600
Query: 601 TLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVI 660
TLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVI
Sbjct: 601 TLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVI 660
Query: 661 AQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVS 720
AQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVS
Sbjct: 661 AQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVS 720
Query: 721 KALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSSSKGELEVGSTVEVRVSY 780
KALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSSSKGELEVGSTVEVRVSY
Sbjct: 721 KALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSSSKGELEVGSTVEVRVSY 780
Query: 781 VENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTVNRQWSRALISG 840
VENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTVNRQWSRALISG
Sbjct: 781 VENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTVNRQWSRALISG 840
Query: 841 IQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQNPFVWDV 900
IQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQNPFVWDV
Sbjct: 841 IQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQNPFVWDV 900
Query: 901 KAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNIVDLLTPFQSACHFLVEKRLARPV 960
KAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNIVDLLTPFQSACHFLVEKRLARPV
Sbjct: 901 KAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNIVDLLTPFQSACHFLVEKRLARPV 960
Query: 961 KLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFYCQLARNANILEQLSCSIT 1020
KLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFYCQLARNANILEQLSCSIT
Sbjct: 961 KLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFYCQLARNANILEQLSCSIT 1020
Query: 1021 QLSKVLLNLKTSPLNPGTLCLAKYTDGNWYRGIVIEKEPKKVFFVDFGNIYVVTSDDLLP 1080
QLSKVLLNLKTSPLNPGTLCLAKYTDGNWYRGIVIEKEPKKVFFVDFGNIYVVTSDDLLP
Sbjct: 1021 QLSKVLLNLKTSPLNPGTLCLAKYTDGNWYRGIVIEKEPKKVFFVDFGNIYVVTSDDLLP 1080
Query: 1081 IPSDAYDVLLLPMQAVRCSLSDIPDHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIE 1140
IPSDAYDVLLLPMQAVRCSLSDIPDHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIE
Sbjct: 1081 IPSDAYDVLLLPMQAVRCSLSDIPDHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIE 1140
Query: 1141 LYGDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETLEEKNENMKLPCTEYLSKSVG 1200
LYGDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETLEEKNENMKLPCTEYLSKSVG
Sbjct: 1141 LYGDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETLEEKNENMKLPCTEYLSKSVG 1200
Query: 1201 YKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLVTQYQDSVGNKNSQVFPLTTEKKEE 1260
YKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLVTQYQDSVGNKNSQVFPLTTEKKEE
Sbjct: 1201 YKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLVTQYQDSVGNKNSQVFPLTTEKKEE 1260
Query: 1261 ISAETPLKTARVEATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSDF 1320
ISAETPLKTARVEATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSDF
Sbjct: 1261 ISAETPLKTARVEATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSDF 1320
Query: 1321 YVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPN 1380
YVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPN
Sbjct: 1321 YVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPN 1380
Query: 1381 DLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQ 1440
DLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQ
Sbjct: 1381 DLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQ 1440
Query: 1441 RTSEAAIRCEFVKFQDRWEVILADEHGIIADDMISRYALSEKSQVELSTQVIKSASSKSV 1500
RTSEAAIRCEFVKFQDRWEVILADEHGIIADDMISRYALSEKSQVELSTQVIKSASSKSV
Sbjct: 1441 RTSEAAIRCEFVKFQDRWEVILADEHGIIADDMISRYALSEKSQVELSTQVIKSASSKSV 1500
Query: 1501 NKSDIDTSVFLNWYNPEKKMIRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVAD 1560
NKSDIDTSVFLNWYNPEKKMIRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVAD
Sbjct: 1501 NKSDIDTSVFLNWYNPEKKMIRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVAD 1560
Query: 1561 RRNCIPCPYIGDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAI 1620
RRNCIPCPYIGDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAI
Sbjct: 1561 RRNCIPCPYIGDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAI 1620
Query: 1621 PSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLA 1680
PSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLA
Sbjct: 1621 PSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLA 1680
Query: 1681 IVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNK 1740
IVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNK
Sbjct: 1681 IVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNK 1740
Query: 1741 IYMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELECH 1800
IYMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELECH
Sbjct: 1741 IYMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELECH 1800
Query: 1801 LVDKAEFDDKYLITGFNTLLPHANETKEILELNSLEVPLSPDDESKEFLELESIELQNSL 1860
LVDKAEFDDKYLITGFNTLLPHANETKEILELNSLEVPLSPDDESKEFLELESIELQNSL
Sbjct: 1801 LVDKAEFDDKYLITGFNTLLPHANETKEILELNSLEVPLSPDDESKEFLELESIELQNSL 1860
Query: 1861 VVDEEKGELSPVPPNVPLSQECVTKGAMELFTLQLPLSCEAEKQPELELPTAQLPLDDKM 1920
VVDEEKGELSPVPPNVPLSQECVTKGAMELFTLQLPLSCEAEKQPELELPTAQLPLDDKM
Sbjct: 1861 VVDEEKGELSPVPPNVPLSQECVTKGAMELFTLQLPLSCEAEKQPELELPTAQLPLDDKM 1920
Query: 1921 DPLSLGVSQKAQESMCTEDMRKSSCVESFDDQRRMSLHLHGADCDPKTQNEMNICEEEFV 1980
DPLSLGVSQKAQESMCTEDMRKSSCVESFDDQRRMSLHLHGADCDPKTQNEMNICEEEFV
Sbjct: 1921 DPLSLGVSQKAQESMCTEDMRKSSCVESFDDQRRMSLHLHGADCDPKTQNEMNICEEEFV 1980
Query: 1981 EYKNRDAISALMPLFSEEESSDGSKHNNGLPDHISAQLQNTYTLKAFTVGSKCVVWSSLR 2040
EYKNRDAISALMPLFSEEESSDGSKHNNGLPDHISAQLQNTYTLKAFTVGSKCVVWSSLR
Sbjct: 1981 EYKNRDAISALMPLFSEEESSDGSKHNNGLPDHISAQLQNTYTLKAFTVGSKCVVWSSLR 2040
Query: 2041 NTWSKCEILETAEEGTRVLNLSNGMEEIVNPENVWNGIPKLDKSPPEKRGLEVMEI 2096
NTWSKCEILETAEEGTRVLNLSNGMEEIVNPENVWNGIPKLDKSPPEKRGLEVMEI
Sbjct: 2041 NTWSKCEILETAEEGTRVLNLSNGMEEIVNPENVWNGIPKLDKSPPEKRGLEVMEI 2096
>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 574 bits (1480), Expect = e-163
Identities = 484/1745 (27%), Positives = 827/1745 (47%), Gaps = 180/1745 (10%)
Query: 16 LRVSFVDVHPDVIPVQLWGLVG-ERRGEYLRLSREIQEAAATRGQWALGSASASPGELCL 74
L +S + P I V+ G+ E +Y L REIQ + + E CL
Sbjct: 161 LTISHIKCLPKDILVKFQGIKSNECEFDYHVLQREIQHTPKVKNNVEID-------EFCL 213
Query: 75 VQ--VGLLWHRCRVVSRQAQESRVFLLDEGRTITAGAGSLAPGRREFFNLPSEVLGCVLA 132
V+ V W R RV+ ++ + V L+D G + +A F LP V+ + A
Sbjct: 214 VEERVSGEWQRGRVMEKKNELYTVLLIDRGEELRVAGPQIASACGNLFELPPRVVFGIFA 273
Query: 133 GLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLVLLEVPDVFQQMR 192
++P G + W A+++ +L G +V G V +L L ++ L EVP + Q
Sbjct: 274 NILPVG---------EKWSPKALNYFKSLVGIQVKGYVQAILPL-QMFLFEVPKIISQAL 323
Query: 193 ELGLARRVPDSLFR---SLLERYLTAATASVGSGVPVLS---RVPLKQKQPGLDYFYPQL 246
EL L R V FR +LE + + P LS + Q LD P L
Sbjct: 324 ELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQPSL 383
Query: 247 QLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTSATWEER 306
+G TE+V ++ P + +CQL + E+ L+ M Y +E
Sbjct: 384 SVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHY------------DTVCQET 431
Query: 307 EESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEY 366
+ D G C + +G W+R +L + P + ++ +DYG E + ++ L ++
Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQ-VKIWFMDYGSSEAIPSIYVKKLKQDF 490
Query: 367 FRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGE 426
+P+ ++PC+L L R Q+ K +LG+ V A I+++ E +YYV+L +
Sbjct: 491 ILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQTQ 550
Query: 427 DG-IN---LNRVFGVQSCC-LADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPAL--- 478
+ +N L + G Q C ++D + + +E + + + + E S+ +L
Sbjct: 551 ESTVNSKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKK 610
Query: 479 ---------RSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASK 529
+++++++ A Y A + +V NPS FW+R H F ++M+ + FY
Sbjct: 611 GILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN 670
Query: 530 LDGVVLKPEPDDLCCVKW-KENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLP 588
+ ++ KPEP CC ++ K+ +YRA++T+++ ++V+ +D GN++++ ++DV++LLP
Sbjct: 671 DEMILRKPEPGLFCCARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLP 730
Query: 589 QFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDE 648
+F +LP LA+ C+LA I+P+ W++ A+ +FKK VL+K +++ ++ K+D +Y + I
Sbjct: 731 EFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSV 790
Query: 649 SRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTES---NKIPFAKTGE 705
+ ++ ++ QAGYA+Y + E + + P VS + S NK+ K
Sbjct: 791 EASENIDVISLMLQAGYAEYFQVELE-------YFPKSVSEYSMLNSESKNKVNIKKVIS 843
Query: 706 GEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSS-- 763
+ + K S + V N S + + F L + P SS
Sbjct: 844 ALLEGPKSKKYHS------NNLVENNLSLPKSLAVNISEFKNPFTL-----SVGPESSWP 892
Query: 764 -SKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLA 822
+ G+ +EV+ S PG F CQL + LK LM IQ Y + P++ A
Sbjct: 893 YKEYIFRPGTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSDPYEIGQTA 952
Query: 823 CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRC 882
C+AK + +W RA + Q + V++ FVDYG ++ V ++++ +I+ FL +++QAFRC
Sbjct: 953 CVAK--YSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRC 1009
Query: 883 SLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN-EELFNIVDLL 941
L + I+PV F W KA + FI ++ + L L C I+AL I+ L+N+VDL
Sbjct: 1010 CLNHFIEPVSCKLFSWTRKAFRDLWNFISSS--RGL-LTCIIYALVIIHPNHLYNLVDLQ 1066
Query: 942 TPFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTF 1001
+ F SA FL+ + A+ + L + S L+SY YS+ +++IGSEE VYI+HI P F
Sbjct: 1067 SSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCYSSFNIQIGSEEEVYISHIYSPQKF 1126
Query: 1002 YCQLARNANILEQLSCSITQLSKVLLNLKTSPLNPGTLCLAKYT-DGNWYRGIVIEKEPK 1060
YCQL RN LE + IT+ S L N N +C++KY DG YR + I +
Sbjct: 1127 YCQLGRNNKDLEMIETKITE-SVNLQNFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSS 1185
Query: 1061 ---KVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDIPD-HIPEEVVVWFQ 1116
+V+FVDFGN +V + L I + ++L PMQA++C LSD+ D IP E+ WF+
Sbjct: 1186 SEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLRDVDIPAEISSWFK 1245
Query: 1117 ETILDKSLKALVVAKDPDGTLIIELYGDNIQISASINKKLGLLSYKDRIRKKESEVLCST 1176
+ L +SLKA++++++ DG L IELY S IN+K+ +L + K+ + C
Sbjct: 1246 DNFLGRSLKAIILSQESDGQLGIELYDG----SQYINEKIKVLLH--AYGKRHCDQAC-C 1298
Query: 1177 TETLEEKNENMKLPCTEYLSKSVGYKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLV 1236
E + NEN + T L G + I + S +Y E K+ Q + N+
Sbjct: 1299 MEKSNKINENKRF--TTSLKGKTGNNYRHNVINKPS-----PVTYSERKIDQLMHPKNIH 1351
Query: 1237 TQY-QDSVGNKNSQVFPLTTEKKEEISAETPLKTARV----EATLSERKIGDSCDKDLPL 1291
++ + SV K V ++ K + S LK ++ L R++G K +
Sbjct: 1352 ARFLKPSVCYKMEPV----SKNKMKTSLNDGLKGIKIVPGAAHILENRRVGQKSVKVVSQ 1407
Query: 1292 KFC--------------------EFPQKTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEI 1331
F + PQ I K YVS+I++ ++F++QL E+E+ I
Sbjct: 1408 SFIRALNQTTSQNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVI 1467
Query: 1332 SHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYG 1391
L++ LN+ R GD++ A + DN YRAVIK+ P + V+FIDYG
Sbjct: 1468 IRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYG 1527
Query: 1392 NVSVVHTNKIGRLDLVNAILPGLCIHCSLQG--FEVPDNKNSKKMMHYFSQRTSEAAIRC 1449
N ++V+T+KI L +P L IH L G + PD K + YF+ + + C
Sbjct: 1528 NSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYC 1587
Query: 1450 EFVKFQD-RWEVILADEHGIIADDMISRYALS--EKSQVEL-----------STQVIKSA 1495
EF+K D +WEV + + + ++++ A S +KS +++ ++ K
Sbjct: 1588 EFLKKHDQKWEVNMICDEKCVINELLKWKACSKLQKSALQMPQVLSQKVRPGDNEMKKGK 1647
Query: 1496 SSKSVNKSDIDTSVFLNWYNPEK--KMIRAYATVIDGPEYFWCQFADTEKLQCLEVEVQT 1553
S++S + + +F K ++ +A + F+ + + +K+ + + T
Sbjct: 1648 SNESEGSMNSNQQLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSDLIVLIT 1707
Query: 1554 AGEQVADRRNCIPCPYI-------GDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFG 1606
E+ + P++ G C+ + + ++R+ + D V V LVD G
Sbjct: 1708 KEEKKS--------PFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCG 1759
Query: 1607 NIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEIT 1666
I + V + +E+ ++P QA PC F S+ + +E + D LEI
Sbjct: 1760 -IYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSKNIS--------FECLFAD-LEIN 1809
Query: 1667 ILEIR 1671
IL ++
Sbjct: 1810 ILFLK 1814
Score = 91.3 bits (225), Expect = 9e-18
Identities = 162/753 (21%), Positives = 299/753 (39%), Gaps = 122/753 (16%)
Query: 462 SQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMC 521
SQ+P + + +I L ++ +NA V + NP+ F I+L ++ S ++R
Sbjct: 1418 SQNPYDLIRPQIK--DLPQPQIYLNAKVKGYVSNISNPANFHIQLAENE---SVIIRLAD 1472
Query: 522 GFYSSASKL-DGVVLKPEPDDLCCVKWK-ENGYYRAIVTK-LDDKSVDVFLVDRGNSENV 578
++A +L + +KP DL ++ +N YRA++ K L S +V +D GNS V
Sbjct: 1473 ALNATARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIV 1532
Query: 579 DWYDVRMLLPQFRQLPILAVKCTLADI-W-PLGKTWSQEAVSFFKKTVLHKELVIHILDK 636
+ + L +F +P L + L+ + W + W + V +F V +K + L K
Sbjct: 1533 NTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKK 1592
Query: 637 QDHQYVIEILDESRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESN 696
D ++ + ++ + + I++++ +K Q+ + ++ S
Sbjct: 1593 HDQKWEVNMICDEKCV---INELLKWKACSKLQKSALQMPQVL---------------SQ 1634
Query: 697 KIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCL 756
K+ + G+ E K + N+ S+ ++ +N + E+ K
Sbjct: 1635 KV---RPGDNEMKKGKSNE--------SEGSMNSNQQLFKIPLEEFKL------------ 1671
Query: 757 EIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPH 816
G+LE + V S G F+ +L++N + L L+ I K +
Sbjct: 1672 ---------GQLEKAEMLNVSKS-----GRFYVKLSKNKKILSDLIVLITKEEKKSPFLS 1717
Query: 817 QRNT---LACLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFL 873
+ L CLAK +W R+ + + V V VD G E+V V N +S E
Sbjct: 1718 MESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIR 1777
Query: 874 KVKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEE 933
+ QA C ++W +N+ KN+ +C +FA IN
Sbjct: 1778 NIPRQAVPCK------------WIW-----------FENS--KNISFEC-LFADLEINIL 1811
Query: 934 LFNIVD------------LLTPFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHD 981
+D LL + + VE+ R ++ +ES + S +
Sbjct: 1812 FLKYLDAVWEVEILVDDLLLLEYLNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFT 1871
Query: 982 MKIGSEELVY---ITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNPGT 1038
+ Y T + DP F QL +I++ L ++ L + L L + PG+
Sbjct: 1872 WVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGS 1931
Query: 1039 LCLAKY-TDGNWYRGIVIEKEPKK--VFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQA 1095
CL KY ++ W R + E P+ + VD+G + + +++ + ++L LP +
Sbjct: 1932 SCLFKYKSEDQWNRVEISEVSPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLS 1991
Query: 1096 VRCSLSDI----PDHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIELYGDNIQISAS 1151
C L I H EE ++F++ + L + L +++ + + A
Sbjct: 1992 YPCILYGILPAKGKHWSEEAKIFFRDFLSKPDLVFQFREYHSETKLKVDVIHEKNNL-AD 2050
Query: 1152 INKKLGLLSYKDRIRKKESEVLCSTTETLEEKN 1184
I GL +Y K+S L + T T KN
Sbjct: 2051 ILVASGLATY-----SKDSPHLDAITATESAKN 2078
Score = 81.3 bits (199), Expect = 9e-15
Identities = 123/597 (20%), Positives = 235/597 (39%), Gaps = 72/597 (12%)
Query: 1251 FPLTTEKKEEISAETP--LKTARVEATLSERKIGDSCDKDLPLKFC-EFPQKTIMPGFKT 1307
F L E EE + P L+ R E +L + D L ++ + Q ++ G
Sbjct: 336 FRLIVEMLEEFPQQMPDLLQHKRPELSLGNK------DTSLDIQHVLDKLQPSLSVGSTE 389
Query: 1308 TVYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDN 1367
+V VS S FY QLI+ E+ +L+ + P ++C +
Sbjct: 390 SVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449
Query: 1368 LWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPD 1427
W+R ++++ P + + + F+DYG+ + + + +L ++P CSL PD
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPD 509
Query: 1428 NK-------------------------NSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVIL 1462
N + ++Y + +T E+ + + + +V+
Sbjct: 510 RDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQTQESTVNSKCLLKTVGTQVLC 569
Query: 1463 ADEHGIIADDMISRYALSEKSQVELSTQVIKSA------SSKSVNKSDIDTSVFLNWYNP 1516
++D IS LSE S ++++ ++S S S+NK I V
Sbjct: 570 P-----MSDSKISNI-LSETSVSDVNSFAVESFMGNIEWSIDSLNKKGI-LKVGFPIKTV 622
Query: 1517 EKKMIRAYATVID---GPEYFWCQFAD-TEKLQCLEVEVQTAGEQVADRRNCIPCPYIGD 1572
+ ++ AY I P FW + D + Q + + + + + P G
Sbjct: 623 QMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGL 682
Query: 1573 PCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDC--VDPKALWAIPSELLSVPMQ 1630
C RY +D +YRA+IT I Y ++V +D+GN + D K L +P E +P
Sbjct: 683 FCCARYSKDRRFYRAVITEI-NGYKINVYFLDYGNTDSIPFFDVKIL--LP-EFCELPAL 738
Query: 1631 AFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLAIVDLKSKGKS 1690
A C L+ E L ++ DYF +++ + + ++ + D + + V+
Sbjct: 739 AMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDV 798
Query: 1691 INEKME----KYSKTGI----KSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNKIY 1742
I+ ++ +Y + + KS Y ++SE K V +KK+ + ++
Sbjct: 799 ISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKN-------KVNIKKVISALLEGPKS 851
Query: 1743 MEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELEC 1799
+ ++ L E + S F++P T ++ P K+ I E++C
Sbjct: 852 KKYHSNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKC 908
Score = 65.9 bits (159), Expect = 4e-10
Identities = 125/611 (20%), Positives = 243/611 (39%), Gaps = 93/611 (15%)
Query: 1122 KSLKALVVAKDPDGTLIIELY-GDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETL 1180
KS+K LV G L++ Y GDN A I K L S++ + + +T++
Sbjct: 1485 KSVKPLV------GDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIY 1538
Query: 1181 EEKNENMKLP---CTEYLS-------------KSVGY---KLPNKEILEESYKP-----Q 1216
E + E + +P +LS K+V Y K+ NK + E K +
Sbjct: 1539 ELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWE 1598
Query: 1217 INSSYKELKLLQSLTKTNLVTQYQDSVGNK----NSQVFPLTTEKKEEISAETPLKTARV 1272
+N E ++ L K ++ Q S + +V P E K+ S E+
Sbjct: 1599 VNMICDEKCVINELLKWKACSKLQKSALQMPQVLSQKVRPGDNEMKKGKSNES------- 1651
Query: 1273 EATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEIS 1332
E +++ + + + P + G + +++ FYV+L +++ +S
Sbjct: 1652 EGSMNSNQ-----------QLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILS 1700
Query: 1333 HLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGN 1392
L + + + + +++G A W+R+ ++E+ +D + V +D G
Sbjct: 1701 DLIVLITKEEKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGI 1760
Query: 1393 VSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQRTSEAAIRCEFV 1452
+V L +P + C FE NSK + F ++ I F+
Sbjct: 1761 YEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFE-----NSKNIS--FECLFADLEINILFL 1813
Query: 1453 KFQDR-WEVILADEHGIIADDMISRYALSEKSQVELSTQVIKSASSKSVNKSDIDTSVFL 1511
K+ D WEV + + ++ + + E++++ L+ V S V+ I + ++
Sbjct: 1814 KYLDAVWEVEILVDDLLLLEYLNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFTWV 1873
Query: 1512 NWYNPEKKMIRAYATVIDGPEYFWCQ---FADTEKLQCLEVEVQTAGEQVADRRNCIPCP 1568
+ N + AT + P F Q F D K + + Q + IP
Sbjct: 1874 QFQND--RQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIP-- 1929
Query: 1569 YIGDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFG-----NIEDCVDPKALWAIPSE 1623
G C+ +Y+ + + R I+ + L V LVD+G + ++ K +P E
Sbjct: 1930 --GSSCLFKYKSEDQWNRVEISEVSPQSLCLV-LVDYGFSFYIRYSEIINLKV---VPEE 1983
Query: 1624 LLSVPMQAFPCCLSGFNISEGL-CSQEGNDYFYEII-------------TEDVLEITILE 1669
LL++P ++PC L G ++G S+E +F + + +E L++ ++
Sbjct: 1984 LLNLPRLSYPCILYGILPAKGKHWSEEAKIFFRDFLSKPDLVFQFREYHSETKLKVDVIH 2043
Query: 1670 IRRDVCDIPLA 1680
+ ++ DI +A
Sbjct: 2044 EKNNLADILVA 2054
Score = 49.7 bits (117), Expect = 3e-05
Identities = 74/356 (20%), Positives = 149/356 (41%), Gaps = 41/356 (11%)
Query: 326 WYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGG 385
W+R+ + E + + L VD G E+V + + L E +P PC +W
Sbjct: 1737 WHRSKVEEKYVDDKVLVFL-VDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKW--IW--- 1790
Query: 386 RGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGED-----GINLNRVFGVQSC 440
+ S+ + L +N I F + V+ V + +D +NLN V
Sbjct: 1791 --FENSKNISFECLFADLEIN--ILFLKYLDAVWEVEILVDDLLLLEYLNLNTV------ 1840
Query: 441 CLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFVKNPS 500
V +++ E +S++P ++ + ++ + + Y V +PS
Sbjct: 1841 ----PVEENKLRLAEIVYNIESKTPVSSC----TIKSFTWVQFQNDRQYSGIATAVSDPS 1892
Query: 501 EFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWK-ENGYYRAIVTK 559
+F I+L L + + L + P C K+K E+ + R +++
Sbjct: 1893 DFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGSS--CLFKYKSEDQWNRVEISE 1950
Query: 560 LDDKSVDVFLVDRGNSENVDWYDV---RMLLPQFRQLPILAVKCTLADIWPL-GKTWSQE 615
+ +S+ + LVD G S + + ++ +++ + LP L+ C L I P GK WS+E
Sbjct: 1951 VSPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEE 2010
Query: 616 AVSFFKKTVLHKELVIHILD-KQDHQYVIEILDESRTGEENISKVIAQAGYAKYQE 670
A FF+ + +LV + + + ++++ E + N++ ++ +G A Y +
Sbjct: 2011 AKIFFRDFLSKPDLVFQFREYHSETKLKVDVIHE----KNNLADILVASGLATYSK 2062
Score = 36.2 bits (82), Expect = 0.35
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Query: 313 PGSPCA-SCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCS---SLRYLLPEYFR 368
PGS C + W R + E PQ VL VDYG + S +L+ + E
Sbjct: 1929 PGSSCLFKYKSEDQWNRVEISEV-SPQSLCLVL-VDYGFSFYIRYSEIINLKVVPEELLN 1986
Query: 369 MPVVTYPCALYGLWDG-GRGWS 389
+P ++YPC LYG+ G+ WS
Sbjct: 1987 LPRLSYPCILYGILPAKGKHWS 2008
>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 574 bits (1480), Expect = e-163
Identities = 484/1745 (27%), Positives = 827/1745 (47%), Gaps = 180/1745 (10%)
Query: 16 LRVSFVDVHPDVIPVQLWGLVG-ERRGEYLRLSREIQEAAATRGQWALGSASASPGELCL 74
L +S + P I V+ G+ E +Y L REIQ + + E CL
Sbjct: 161 LTISHIKCLPKDILVKFQGIKSNECEFDYHVLQREIQHTPKVKNNVEID-------EFCL 213
Query: 75 VQ--VGLLWHRCRVVSRQAQESRVFLLDEGRTITAGAGSLAPGRREFFNLPSEVLGCVLA 132
V+ V W R RV+ ++ + V L+D G + +A F LP V+ + A
Sbjct: 214 VEERVSGEWQRGRVMEKKNELYTVLLIDRGEELRVAGPQIASACGNLFELPPRVVFGIFA 273
Query: 133 GLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLVLLEVPDVFQQMR 192
++P G + W A+++ +L G +V G V +L L ++ L EVP + Q
Sbjct: 274 NILPVG---------EKWSPKALNYFKSLVGIQVKGYVQAILPL-QMFLFEVPKIISQAL 323
Query: 193 ELGLARRVPDSLFR---SLLERYLTAATASVGSGVPVLS---RVPLKQKQPGLDYFYPQL 246
EL L R V FR +LE + + P LS + Q LD P L
Sbjct: 324 ELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQPSL 383
Query: 247 QLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTSATWEER 306
+G TE+V ++ P + +CQL + E+ L+ M Y +E
Sbjct: 384 SVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHY------------DTVCQET 431
Query: 307 EESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEY 366
+ D G C + +G W+R +L + P + ++ +DYG E + ++ L ++
Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQ-VKIWFMDYGSSEAIPSIYVKKLKQDF 490
Query: 367 FRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGE 426
+P+ ++PC+L L R Q+ K +LG+ V A I+++ E +YYV+L +
Sbjct: 491 ILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQTQ 550
Query: 427 DG-IN---LNRVFGVQSCC-LADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPAL--- 478
+ +N L + G Q C ++D + + +E + + + + E S+ +L
Sbjct: 551 ESTVNSKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKK 610
Query: 479 ---------RSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASK 529
+++++++ A Y A + +V NPS FW+R H F ++M+ + FY
Sbjct: 611 GILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN 670
Query: 530 LDGVVLKPEPDDLCCVKW-KENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLP 588
+ ++ KPEP CC ++ K+ +YRA++T+++ ++V+ +D GN++++ ++DV++LLP
Sbjct: 671 DEMILRKPEPGLFCCARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLP 730
Query: 589 QFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDE 648
+F +LP LA+ C+LA I+P+ W++ A+ +FKK VL+K +++ ++ K+D +Y + I
Sbjct: 731 EFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSV 790
Query: 649 SRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTES---NKIPFAKTGE 705
+ ++ ++ QAGYA+Y + E + + P VS + S NK+ K
Sbjct: 791 EASENIDVISLMLQAGYAEYFQVELE-------YFPKSVSEYSMLNSESKNKVNIKKVIS 843
Query: 706 GEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSS-- 763
+ + K S + V N S + + F L + P SS
Sbjct: 844 ALLEGPKSKKYHS------NNLVENNLSLPKSLAVNISEFKNPFTL-----SVGPESSWP 892
Query: 764 -SKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLA 822
+ G+ +EV+ S PG F CQL + LK LM IQ Y + P++ A
Sbjct: 893 YKEYIFRPGTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSDPYEIGQTA 952
Query: 823 CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRC 882
C+AK + +W RA + Q + V++ FVDYG ++ V ++++ +I+ FL +++QAFRC
Sbjct: 953 CVAK--YSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRC 1009
Query: 883 SLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN-EELFNIVDLL 941
L + I+PV F W KA + FI ++ + L L C I+AL I+ L+N+VDL
Sbjct: 1010 CLNHFIEPVSCKLFSWTRKAFRDLWNFISSS--RGL-LTCIIYALVIIHPNHLYNLVDLQ 1066
Query: 942 TPFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTF 1001
+ F SA FL+ + A+ + L + S L+SY YS+ +++IGSEE VYI+HI P F
Sbjct: 1067 SSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCYSSFNIQIGSEEEVYISHIYSPQKF 1126
Query: 1002 YCQLARNANILEQLSCSITQLSKVLLNLKTSPLNPGTLCLAKYT-DGNWYRGIVIEKEPK 1060
YCQL RN LE + IT+ S L N N +C++KY DG YR + I +
Sbjct: 1127 YCQLGRNNKDLEMIETKITE-SVNLQNFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSS 1185
Query: 1061 ---KVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDIPD-HIPEEVVVWFQ 1116
+V+FVDFGN +V + L I + ++L PMQA++C LSD+ D IP E+ WF+
Sbjct: 1186 SEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLRDVDIPAEISSWFK 1245
Query: 1117 ETILDKSLKALVVAKDPDGTLIIELYGDNIQISASINKKLGLLSYKDRIRKKESEVLCST 1176
+ L +SLKA++++++ DG L IELY S IN+K+ +L + K+ + C
Sbjct: 1246 DNFLGRSLKAIILSQESDGQLGIELYDG----SQYINEKIKVLLH--AYGKRHCDQAC-C 1298
Query: 1177 TETLEEKNENMKLPCTEYLSKSVGYKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLV 1236
E + NEN + T L G + I + S +Y E K+ Q + N+
Sbjct: 1299 MEKSNKINENKRF--TTSLKGKTGNNYRHNVINKPS-----PVTYSERKIDQLMHPKNIH 1351
Query: 1237 TQY-QDSVGNKNSQVFPLTTEKKEEISAETPLKTARV----EATLSERKIGDSCDKDLPL 1291
++ + SV K V ++ K + S LK ++ L R++G K +
Sbjct: 1352 ARFLKPSVCYKMEPV----SKNKMKTSLNDGLKGIKIVPGAAHILENRRVGQKSVKVVSQ 1407
Query: 1292 KFC--------------------EFPQKTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEI 1331
F + PQ I K YVS+I++ ++F++QL E+E+ I
Sbjct: 1408 SFIRALNQTTSQNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVI 1467
Query: 1332 SHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYG 1391
L++ LN+ R GD++ A + DN YRAVIK+ P + V+FIDYG
Sbjct: 1468 IRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYG 1527
Query: 1392 NVSVVHTNKIGRLDLVNAILPGLCIHCSLQG--FEVPDNKNSKKMMHYFSQRTSEAAIRC 1449
N ++V+T+KI L +P L IH L G + PD K + YF+ + + C
Sbjct: 1528 NSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYC 1587
Query: 1450 EFVKFQD-RWEVILADEHGIIADDMISRYALS--EKSQVEL-----------STQVIKSA 1495
EF+K D +WEV + + + ++++ A S +KS +++ ++ K
Sbjct: 1588 EFLKKHDQKWEVNMICDEKCVINELLKWKACSKLQKSALQMPQVLSQKVRPGDNEMKKGK 1647
Query: 1496 SSKSVNKSDIDTSVFLNWYNPEK--KMIRAYATVIDGPEYFWCQFADTEKLQCLEVEVQT 1553
S++S + + +F K ++ +A + F+ + + +K+ + + T
Sbjct: 1648 SNESEGSMNSNQQLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSDLIVLIT 1707
Query: 1554 AGEQVADRRNCIPCPYI-------GDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFG 1606
E+ + P++ G C+ + + ++R+ + D V V LVD G
Sbjct: 1708 KEEKKS--------PFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCG 1759
Query: 1607 NIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEIT 1666
I + V + +E+ ++P QA PC F S+ + +E + D LEI
Sbjct: 1760 -IYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSKNIS--------FECLFAD-LEIN 1809
Query: 1667 ILEIR 1671
IL ++
Sbjct: 1810 ILFLK 1814
Score = 91.3 bits (225), Expect = 9e-18
Identities = 162/753 (21%), Positives = 299/753 (39%), Gaps = 122/753 (16%)
Query: 462 SQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMC 521
SQ+P + + +I L ++ +NA V + NP+ F I+L ++ S ++R
Sbjct: 1418 SQNPYDLIRPQIK--DLPQPQIYLNAKVKGYVSNISNPANFHIQLAENE---SVIIRLAD 1472
Query: 522 GFYSSASKL-DGVVLKPEPDDLCCVKWK-ENGYYRAIVTK-LDDKSVDVFLVDRGNSENV 578
++A +L + +KP DL ++ +N YRA++ K L S +V +D GNS V
Sbjct: 1473 ALNATARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIV 1532
Query: 579 DWYDVRMLLPQFRQLPILAVKCTLADI-W-PLGKTWSQEAVSFFKKTVLHKELVIHILDK 636
+ + L +F +P L + L+ + W + W + V +F V +K + L K
Sbjct: 1533 NTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKK 1592
Query: 637 QDHQYVIEILDESRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESN 696
D ++ + ++ + + I++++ +K Q+ + ++ S
Sbjct: 1593 HDQKWEVNMICDEKCV---INELLKWKACSKLQKSALQMPQVL---------------SQ 1634
Query: 697 KIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCL 756
K+ + G+ E K + N+ S+ ++ +N + E+ K
Sbjct: 1635 KV---RPGDNEMKKGKSNE--------SEGSMNSNQQLFKIPLEEFKL------------ 1671
Query: 757 EIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPH 816
G+LE + V S G F+ +L++N + L L+ I K +
Sbjct: 1672 ---------GQLEKAEMLNVSKS-----GRFYVKLSKNKKILSDLIVLITKEEKKSPFLS 1717
Query: 817 QRNT---LACLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFL 873
+ L CLAK +W R+ + + V V VD G E+V V N +S E
Sbjct: 1718 MESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIR 1777
Query: 874 KVKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEE 933
+ QA C ++W +N+ KN+ +C +FA IN
Sbjct: 1778 NIPRQAVPCK------------WIW-----------FENS--KNISFEC-LFADLEINIL 1811
Query: 934 LFNIVD------------LLTPFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHD 981
+D LL + + VE+ R ++ +ES + S +
Sbjct: 1812 FLKYLDAVWEVEILVDDLLLLEYLNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFT 1871
Query: 982 MKIGSEELVY---ITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNPGT 1038
+ Y T + DP F QL +I++ L ++ L + L L + PG+
Sbjct: 1872 WVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGS 1931
Query: 1039 LCLAKY-TDGNWYRGIVIEKEPKK--VFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQA 1095
CL KY ++ W R + E P+ + VD+G + + +++ + ++L LP +
Sbjct: 1932 SCLFKYKSEDQWNRVEISEVSPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLS 1991
Query: 1096 VRCSLSDI----PDHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIELYGDNIQISAS 1151
C L I H EE ++F++ + L + L +++ + + A
Sbjct: 1992 YPCILYGILPAKGKHWSEEAKIFFRDFLSKPDLVFQFREYHSETKLKVDVIHEKNNL-AD 2050
Query: 1152 INKKLGLLSYKDRIRKKESEVLCSTTETLEEKN 1184
I GL +Y K+S L + T T KN
Sbjct: 2051 ILVASGLATY-----SKDSPHLDAITATESAKN 2078
Score = 81.3 bits (199), Expect = 9e-15
Identities = 123/597 (20%), Positives = 235/597 (39%), Gaps = 72/597 (12%)
Query: 1251 FPLTTEKKEEISAETP--LKTARVEATLSERKIGDSCDKDLPLKFC-EFPQKTIMPGFKT 1307
F L E EE + P L+ R E +L + D L ++ + Q ++ G
Sbjct: 336 FRLIVEMLEEFPQQMPDLLQHKRPELSLGNK------DTSLDIQHVLDKLQPSLSVGSTE 389
Query: 1308 TVYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDN 1367
+V VS S FY QLI+ E+ +L+ + P ++C +
Sbjct: 390 SVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449
Query: 1368 LWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPD 1427
W+R ++++ P + + + F+DYG+ + + + +L ++P CSL PD
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPD 509
Query: 1428 NK-------------------------NSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVIL 1462
N + ++Y + +T E+ + + + +V+
Sbjct: 510 RDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQTQESTVNSKCLLKTVGTQVLC 569
Query: 1463 ADEHGIIADDMISRYALSEKSQVELSTQVIKSA------SSKSVNKSDIDTSVFLNWYNP 1516
++D IS LSE S ++++ ++S S S+NK I V
Sbjct: 570 P-----MSDSKISNI-LSETSVSDVNSFAVESFMGNIEWSIDSLNKKGI-LKVGFPIKTV 622
Query: 1517 EKKMIRAYATVID---GPEYFWCQFAD-TEKLQCLEVEVQTAGEQVADRRNCIPCPYIGD 1572
+ ++ AY I P FW + D + Q + + + + + P G
Sbjct: 623 QMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGL 682
Query: 1573 PCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDC--VDPKALWAIPSELLSVPMQ 1630
C RY +D +YRA+IT I Y ++V +D+GN + D K L +P E +P
Sbjct: 683 FCCARYSKDRRFYRAVITEI-NGYKINVYFLDYGNTDSIPFFDVKIL--LP-EFCELPAL 738
Query: 1631 AFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLAIVDLKSKGKS 1690
A C L+ E L ++ DYF +++ + + ++ + D + + V+
Sbjct: 739 AMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDV 798
Query: 1691 INEKME----KYSKTGI----KSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNKIY 1742
I+ ++ +Y + + KS Y ++SE K V +KK+ + ++
Sbjct: 799 ISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKN-------KVNIKKVISALLEGPKS 851
Query: 1743 MEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELEC 1799
+ ++ L E + S F++P T ++ P K+ I E++C
Sbjct: 852 KKYHSNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKC 908
Score = 65.9 bits (159), Expect = 4e-10
Identities = 125/611 (20%), Positives = 243/611 (39%), Gaps = 93/611 (15%)
Query: 1122 KSLKALVVAKDPDGTLIIELY-GDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETL 1180
KS+K LV G L++ Y GDN A I K L S++ + + +T++
Sbjct: 1485 KSVKPLV------GDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIY 1538
Query: 1181 EEKNENMKLP---CTEYLS-------------KSVGY---KLPNKEILEESYKP-----Q 1216
E + E + +P +LS K+V Y K+ NK + E K +
Sbjct: 1539 ELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWE 1598
Query: 1217 INSSYKELKLLQSLTKTNLVTQYQDSVGNK----NSQVFPLTTEKKEEISAETPLKTARV 1272
+N E ++ L K ++ Q S + +V P E K+ S E+
Sbjct: 1599 VNMICDEKCVINELLKWKACSKLQKSALQMPQVLSQKVRPGDNEMKKGKSNES------- 1651
Query: 1273 EATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEIS 1332
E +++ + + + P + G + +++ FYV+L +++ +S
Sbjct: 1652 EGSMNSNQ-----------QLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILS 1700
Query: 1333 HLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGN 1392
L + + + + +++G A W+R+ ++E+ +D + V +D G
Sbjct: 1701 DLIVLITKEEKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGI 1760
Query: 1393 VSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQRTSEAAIRCEFV 1452
+V L +P + C FE NSK + F ++ I F+
Sbjct: 1761 YEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFE-----NSKNIS--FECLFADLEINILFL 1813
Query: 1453 KFQDR-WEVILADEHGIIADDMISRYALSEKSQVELSTQVIKSASSKSVNKSDIDTSVFL 1511
K+ D WEV + + ++ + + E++++ L+ V S V+ I + ++
Sbjct: 1814 KYLDAVWEVEILVDDLLLLEYLNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFTWV 1873
Query: 1512 NWYNPEKKMIRAYATVIDGPEYFWCQ---FADTEKLQCLEVEVQTAGEQVADRRNCIPCP 1568
+ N + AT + P F Q F D K + + Q + IP
Sbjct: 1874 QFQND--RQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIP-- 1929
Query: 1569 YIGDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFG-----NIEDCVDPKALWAIPSE 1623
G C+ +Y+ + + R I+ + L V LVD+G + ++ K +P E
Sbjct: 1930 --GSSCLFKYKSEDQWNRVEISEVSPQSLCLV-LVDYGFSFYIRYSEIINLKV---VPEE 1983
Query: 1624 LLSVPMQAFPCCLSGFNISEGL-CSQEGNDYFYEII-------------TEDVLEITILE 1669
LL++P ++PC L G ++G S+E +F + + +E L++ ++
Sbjct: 1984 LLNLPRLSYPCILYGILPAKGKHWSEEAKIFFRDFLSKPDLVFQFREYHSETKLKVDVIH 2043
Query: 1670 IRRDVCDIPLA 1680
+ ++ DI +A
Sbjct: 2044 EKNNLADILVA 2054
Score = 49.7 bits (117), Expect = 3e-05
Identities = 74/356 (20%), Positives = 149/356 (41%), Gaps = 41/356 (11%)
Query: 326 WYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGG 385
W+R+ + E + + L VD G E+V + + L E +P PC +W
Sbjct: 1737 WHRSKVEEKYVDDKVLVFL-VDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKW--IW--- 1790
Query: 386 RGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGED-----GINLNRVFGVQSC 440
+ S+ + L +N I F + V+ V + +D +NLN V
Sbjct: 1791 --FENSKNISFECLFADLEIN--ILFLKYLDAVWEVEILVDDLLLLEYLNLNTV------ 1840
Query: 441 CLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFVKNPS 500
V +++ E +S++P ++ + ++ + + Y V +PS
Sbjct: 1841 ----PVEENKLRLAEIVYNIESKTPVSSC----TIKSFTWVQFQNDRQYSGIATAVSDPS 1892
Query: 501 EFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWK-ENGYYRAIVTK 559
+F I+L L + + L + P C K+K E+ + R +++
Sbjct: 1893 DFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGSS--CLFKYKSEDQWNRVEISE 1950
Query: 560 LDDKSVDVFLVDRGNSENVDWYDV---RMLLPQFRQLPILAVKCTLADIWPL-GKTWSQE 615
+ +S+ + LVD G S + + ++ +++ + LP L+ C L I P GK WS+E
Sbjct: 1951 VSPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEE 2010
Query: 616 AVSFFKKTVLHKELVIHILD-KQDHQYVIEILDESRTGEENISKVIAQAGYAKYQE 670
A FF+ + +LV + + + ++++ E + N++ ++ +G A Y +
Sbjct: 2011 AKIFFRDFLSKPDLVFQFREYHSETKLKVDVIHE----KNNLADILVASGLATYSK 2062
Score = 36.2 bits (82), Expect = 0.35
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Query: 313 PGSPCA-SCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCS---SLRYLLPEYFR 368
PGS C + W R + E PQ VL VDYG + S +L+ + E
Sbjct: 1929 PGSSCLFKYKSEDQWNRVEISEV-SPQSLCLVL-VDYGFSFYIRYSEIINLKVVPEELLN 1986
Query: 369 MPVVTYPCALYGLWDG-GRGWS 389
+P ++YPC LYG+ G+ WS
Sbjct: 1987 LPRLSYPCILYGILPAKGKHWS 2008
>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 574 bits (1480), Expect = e-163
Identities = 484/1745 (27%), Positives = 827/1745 (47%), Gaps = 180/1745 (10%)
Query: 16 LRVSFVDVHPDVIPVQLWGLVG-ERRGEYLRLSREIQEAAATRGQWALGSASASPGELCL 74
L +S + P I V+ G+ E +Y L REIQ + + E CL
Sbjct: 161 LTISHIKCLPKDILVKFQGIKSNECEFDYHVLQREIQHTPKVKNNVEID-------EFCL 213
Query: 75 VQ--VGLLWHRCRVVSRQAQESRVFLLDEGRTITAGAGSLAPGRREFFNLPSEVLGCVLA 132
V+ V W R RV+ ++ + V L+D G + +A F LP V+ + A
Sbjct: 214 VEERVSGEWQRGRVMEKKNELYTVLLIDRGEELRVAGPQIASACGNLFELPPRVVFGIFA 273
Query: 133 GLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLVLLEVPDVFQQMR 192
++P G + W A+++ +L G +V G V +L L ++ L EVP + Q
Sbjct: 274 NILPVG---------EKWSPKALNYFKSLVGIQVKGYVQAILPL-QMFLFEVPKIISQAL 323
Query: 193 ELGLARRVPDSLFR---SLLERYLTAATASVGSGVPVLS---RVPLKQKQPGLDYFYPQL 246
EL L R V FR +LE + + P LS + Q LD P L
Sbjct: 324 ELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLGNKDTSLDIQHVLDKLQPSL 383
Query: 247 QLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTSATWEER 306
+G TE+V ++ P + +CQL + E+ L+ M Y +E
Sbjct: 384 SVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHY------------DTVCQET 431
Query: 307 EESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEY 366
+ D G C + +G W+R +L + P + ++ +DYG E + ++ L ++
Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQ-VKIWFMDYGSSEAIPSIYVKKLKQDF 490
Query: 367 FRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGE 426
+P+ ++PC+L L R Q+ K +LG+ V A I+++ E +YYV+L +
Sbjct: 491 ILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQTQ 550
Query: 427 DG-IN---LNRVFGVQSCC-LADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPAL--- 478
+ +N L + G Q C ++D + + +E + + + + E S+ +L
Sbjct: 551 ESTVNSKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKK 610
Query: 479 ---------RSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASK 529
+++++++ A Y A + +V NPS FW+R H F ++M+ + FY
Sbjct: 611 GILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN 670
Query: 530 LDGVVLKPEPDDLCCVKW-KENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLP 588
+ ++ KPEP CC ++ K+ +YRA++T+++ ++V+ +D GN++++ ++DV++LLP
Sbjct: 671 DEMILRKPEPGLFCCARYSKDRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLP 730
Query: 589 QFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDE 648
+F +LP LA+ C+LA I+P+ W++ A+ +FKK VL+K +++ ++ K+D +Y + I
Sbjct: 731 EFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSV 790
Query: 649 SRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTES---NKIPFAKTGE 705
+ ++ ++ QAGYA+Y + E + + P VS + S NK+ K
Sbjct: 791 EASENIDVISLMLQAGYAEYFQVELE-------YFPKSVSEYSMLNSESKNKVNIKKVIS 843
Query: 706 GEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSS-- 763
+ + K S + V N S + + F L + P SS
Sbjct: 844 ALLEGPKSKKYHS------NNLVENNLSLPKSLAVNISEFKNPFTL-----SVGPESSWP 892
Query: 764 -SKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLA 822
+ G+ +EV+ S PG F CQL + LK LM IQ Y + P++ A
Sbjct: 893 YKEYIFRPGTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSDPYEIGQTA 952
Query: 823 CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRC 882
C+AK + +W RA + Q + V++ FVDYG ++ V ++++ +I+ FL +++QAFRC
Sbjct: 953 CVAK--YSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRC 1009
Query: 883 SLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN-EELFNIVDLL 941
L + I+PV F W KA + FI ++ + L L C I+AL I+ L+N+VDL
Sbjct: 1010 CLNHFIEPVSCKLFSWTRKAFRDLWNFISSS--RGL-LTCIIYALVIIHPNHLYNLVDLQ 1066
Query: 942 TPFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTF 1001
+ F SA FL+ + A+ + L + S L+SY YS+ +++IGSEE VYI+HI P F
Sbjct: 1067 SSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCYSSFNIQIGSEEEVYISHIYSPQKF 1126
Query: 1002 YCQLARNANILEQLSCSITQLSKVLLNLKTSPLNPGTLCLAKYT-DGNWYRGIVIEKEPK 1060
YCQL RN LE + IT+ S L N N +C++KY DG YR + I +
Sbjct: 1127 YCQLGRNNKDLEMIETKITE-SVNLQNFPKYDSNKMRVCISKYVEDGLSYRALAIPTDSS 1185
Query: 1061 ---KVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDIPD-HIPEEVVVWFQ 1116
+V+FVDFGN +V + L I + ++L PMQA++C LSD+ D IP E+ WF+
Sbjct: 1186 SEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLRDVDIPAEISSWFK 1245
Query: 1117 ETILDKSLKALVVAKDPDGTLIIELYGDNIQISASINKKLGLLSYKDRIRKKESEVLCST 1176
+ L +SLKA++++++ DG L IELY S IN+K+ +L + K+ + C
Sbjct: 1246 DNFLGRSLKAIILSQESDGQLGIELYDG----SQYINEKIKVLLH--AYGKRHCDQAC-C 1298
Query: 1177 TETLEEKNENMKLPCTEYLSKSVGYKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLV 1236
E + NEN + T L G + I + S +Y E K+ Q + N+
Sbjct: 1299 MEKSNKINENKRF--TTSLKGKTGNNYRHNVINKPS-----PVTYSERKIDQLMHPKNIH 1351
Query: 1237 TQY-QDSVGNKNSQVFPLTTEKKEEISAETPLKTARV----EATLSERKIGDSCDKDLPL 1291
++ + SV K V ++ K + S LK ++ L R++G K +
Sbjct: 1352 ARFLKPSVCYKMEPV----SKNKMKTSLNDGLKGIKIVPGAAHILENRRVGQKSVKVVSQ 1407
Query: 1292 KFC--------------------EFPQKTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEI 1331
F + PQ I K YVS+I++ ++F++QL E+E+ I
Sbjct: 1408 SFIRALNQTTSQNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVI 1467
Query: 1332 SHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYG 1391
L++ LN+ R GD++ A + DN YRAVIK+ P + V+FIDYG
Sbjct: 1468 IRLADALNATARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYG 1527
Query: 1392 NVSVVHTNKIGRLDLVNAILPGLCIHCSLQG--FEVPDNKNSKKMMHYFSQRTSEAAIRC 1449
N ++V+T+KI L +P L IH L G + PD K + YF+ + + C
Sbjct: 1528 NSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYC 1587
Query: 1450 EFVKFQD-RWEVILADEHGIIADDMISRYALS--EKSQVEL-----------STQVIKSA 1495
EF+K D +WEV + + + ++++ A S +KS +++ ++ K
Sbjct: 1588 EFLKKHDQKWEVNMICDEKCVINELLKWKACSKLQKSALQMPQVLSQKVRPGDNEMKKGK 1647
Query: 1496 SSKSVNKSDIDTSVFLNWYNPEK--KMIRAYATVIDGPEYFWCQFADTEKLQCLEVEVQT 1553
S++S + + +F K ++ +A + F+ + + +K+ + + T
Sbjct: 1648 SNESEGSMNSNQQLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSDLIVLIT 1707
Query: 1554 AGEQVADRRNCIPCPYI-------GDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFG 1606
E+ + P++ G C+ + + ++R+ + D V V LVD G
Sbjct: 1708 KEEKKS--------PFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCG 1759
Query: 1607 NIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEIT 1666
I + V + +E+ ++P QA PC F S+ + +E + D LEI
Sbjct: 1760 -IYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSKNIS--------FECLFAD-LEIN 1809
Query: 1667 ILEIR 1671
IL ++
Sbjct: 1810 ILFLK 1814
Score = 91.3 bits (225), Expect = 9e-18
Identities = 162/753 (21%), Positives = 299/753 (39%), Gaps = 122/753 (16%)
Query: 462 SQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMC 521
SQ+P + + +I L ++ +NA V + NP+ F I+L ++ S ++R
Sbjct: 1418 SQNPYDLIRPQIK--DLPQPQIYLNAKVKGYVSNISNPANFHIQLAENE---SVIIRLAD 1472
Query: 522 GFYSSASKL-DGVVLKPEPDDLCCVKWK-ENGYYRAIVTK-LDDKSVDVFLVDRGNSENV 578
++A +L + +KP DL ++ +N YRA++ K L S +V +D GNS V
Sbjct: 1473 ALNATARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIV 1532
Query: 579 DWYDVRMLLPQFRQLPILAVKCTLADI-W-PLGKTWSQEAVSFFKKTVLHKELVIHILDK 636
+ + L +F +P L + L+ + W + W + V +F V +K + L K
Sbjct: 1533 NTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKK 1592
Query: 637 QDHQYVIEILDESRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESN 696
D ++ + ++ + + I++++ +K Q+ + ++ S
Sbjct: 1593 HDQKWEVNMICDEKCV---INELLKWKACSKLQKSALQMPQVL---------------SQ 1634
Query: 697 KIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCL 756
K+ + G+ E K + N+ S+ ++ +N + E+ K
Sbjct: 1635 KV---RPGDNEMKKGKSNE--------SEGSMNSNQQLFKIPLEEFKL------------ 1671
Query: 757 EIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPH 816
G+LE + V S G F+ +L++N + L L+ I K +
Sbjct: 1672 ---------GQLEKAEMLNVSKS-----GRFYVKLSKNKKILSDLIVLITKEEKKSPFLS 1717
Query: 817 QRNT---LACLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFL 873
+ L CLAK +W R+ + + V V VD G E+V V N +S E
Sbjct: 1718 MESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIR 1777
Query: 874 KVKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEE 933
+ QA C ++W +N+ KN+ +C +FA IN
Sbjct: 1778 NIPRQAVPCK------------WIW-----------FENS--KNISFEC-LFADLEINIL 1811
Query: 934 LFNIVD------------LLTPFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHD 981
+D LL + + VE+ R ++ +ES + S +
Sbjct: 1812 FLKYLDAVWEVEILVDDLLLLEYLNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFT 1871
Query: 982 MKIGSEELVY---ITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNPGT 1038
+ Y T + DP F QL +I++ L ++ L + L L + PG+
Sbjct: 1872 WVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGS 1931
Query: 1039 LCLAKY-TDGNWYRGIVIEKEPKK--VFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQA 1095
CL KY ++ W R + E P+ + VD+G + + +++ + ++L LP +
Sbjct: 1932 SCLFKYKSEDQWNRVEISEVSPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLS 1991
Query: 1096 VRCSLSDI----PDHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIELYGDNIQISAS 1151
C L I H EE ++F++ + L + L +++ + + A
Sbjct: 1992 YPCILYGILPAKGKHWSEEAKIFFRDFLSKPDLVFQFREYHSETKLKVDVIHEKNNL-AD 2050
Query: 1152 INKKLGLLSYKDRIRKKESEVLCSTTETLEEKN 1184
I GL +Y K+S L + T T KN
Sbjct: 2051 ILVASGLATY-----SKDSPHLDAITATESAKN 2078
Score = 81.3 bits (199), Expect = 9e-15
Identities = 123/597 (20%), Positives = 235/597 (39%), Gaps = 72/597 (12%)
Query: 1251 FPLTTEKKEEISAETP--LKTARVEATLSERKIGDSCDKDLPLKFC-EFPQKTIMPGFKT 1307
F L E EE + P L+ R E +L + D L ++ + Q ++ G
Sbjct: 336 FRLIVEMLEEFPQQMPDLLQHKRPELSLGNK------DTSLDIQHVLDKLQPSLSVGSTE 389
Query: 1308 TVYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDN 1367
+V VS S FY QLI+ E+ +L+ + P ++C +
Sbjct: 390 SVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449
Query: 1368 LWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPD 1427
W+R ++++ P + + + F+DYG+ + + + +L ++P CSL PD
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPD 509
Query: 1428 NK-------------------------NSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVIL 1462
N + ++Y + +T E+ + + + +V+
Sbjct: 510 RDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQTQESTVNSKCLLKTVGTQVLC 569
Query: 1463 ADEHGIIADDMISRYALSEKSQVELSTQVIKSA------SSKSVNKSDIDTSVFLNWYNP 1516
++D IS LSE S ++++ ++S S S+NK I V
Sbjct: 570 P-----MSDSKISNI-LSETSVSDVNSFAVESFMGNIEWSIDSLNKKGI-LKVGFPIKTV 622
Query: 1517 EKKMIRAYATVID---GPEYFWCQFAD-TEKLQCLEVEVQTAGEQVADRRNCIPCPYIGD 1572
+ ++ AY I P FW + D + Q + + + + + P G
Sbjct: 623 QMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGL 682
Query: 1573 PCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDC--VDPKALWAIPSELLSVPMQ 1630
C RY +D +YRA+IT I Y ++V +D+GN + D K L +P E +P
Sbjct: 683 FCCARYSKDRRFYRAVITEI-NGYKINVYFLDYGNTDSIPFFDVKIL--LP-EFCELPAL 738
Query: 1631 AFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLAIVDLKSKGKS 1690
A C L+ E L ++ DYF +++ + + ++ + D + + V+
Sbjct: 739 AMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDV 798
Query: 1691 INEKME----KYSKTGI----KSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNKIY 1742
I+ ++ +Y + + KS Y ++SE K V +KK+ + ++
Sbjct: 799 ISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKN-------KVNIKKVISALLEGPKS 851
Query: 1743 MEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELEC 1799
+ ++ L E + S F++P T ++ P K+ I E++C
Sbjct: 852 KKYHSNNLVENNLSLPKSLAVNISEFKNPFTLSVGPESSWPYKEYIFRPGTVLEVKC 908
Score = 65.9 bits (159), Expect = 4e-10
Identities = 125/611 (20%), Positives = 243/611 (39%), Gaps = 93/611 (15%)
Query: 1122 KSLKALVVAKDPDGTLIIELY-GDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETL 1180
KS+K LV G L++ Y GDN A I K L S++ + + +T++
Sbjct: 1485 KSVKPLV------GDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIY 1538
Query: 1181 EEKNENMKLP---CTEYLS-------------KSVGY---KLPNKEILEESYKP-----Q 1216
E + E + +P +LS K+V Y K+ NK + E K +
Sbjct: 1539 ELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHDQKWE 1598
Query: 1217 INSSYKELKLLQSLTKTNLVTQYQDSVGNK----NSQVFPLTTEKKEEISAETPLKTARV 1272
+N E ++ L K ++ Q S + +V P E K+ S E+
Sbjct: 1599 VNMICDEKCVINELLKWKACSKLQKSALQMPQVLSQKVRPGDNEMKKGKSNES------- 1651
Query: 1273 EATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEIS 1332
E +++ + + + P + G + +++ FYV+L +++ +S
Sbjct: 1652 EGSMNSNQ-----------QLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILS 1700
Query: 1333 HLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGN 1392
L + + + + +++G A W+R+ ++E+ +D + V +D G
Sbjct: 1701 DLIVLITKEEKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGI 1760
Query: 1393 VSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQRTSEAAIRCEFV 1452
+V L +P + C FE NSK + F ++ I F+
Sbjct: 1761 YEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFE-----NSKNIS--FECLFADLEINILFL 1813
Query: 1453 KFQDR-WEVILADEHGIIADDMISRYALSEKSQVELSTQVIKSASSKSVNKSDIDTSVFL 1511
K+ D WEV + + ++ + + E++++ L+ V S V+ I + ++
Sbjct: 1814 KYLDAVWEVEILVDDLLLLEYLNLNTVPVEENKLRLAEIVYNIESKTPVSSCTIKSFTWV 1873
Query: 1512 NWYNPEKKMIRAYATVIDGPEYFWCQ---FADTEKLQCLEVEVQTAGEQVADRRNCIPCP 1568
+ N + AT + P F Q F D K + + Q + IP
Sbjct: 1874 QFQND--RQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIP-- 1929
Query: 1569 YIGDPCIVRYREDGHYYRALITNICEDYLVSVRLVDFG-----NIEDCVDPKALWAIPSE 1623
G C+ +Y+ + + R I+ + L V LVD+G + ++ K +P E
Sbjct: 1930 --GSSCLFKYKSEDQWNRVEISEVSPQSLCLV-LVDYGFSFYIRYSEIINLKV---VPEE 1983
Query: 1624 LLSVPMQAFPCCLSGFNISEGL-CSQEGNDYFYEII-------------TEDVLEITILE 1669
LL++P ++PC L G ++G S+E +F + + +E L++ ++
Sbjct: 1984 LLNLPRLSYPCILYGILPAKGKHWSEEAKIFFRDFLSKPDLVFQFREYHSETKLKVDVIH 2043
Query: 1670 IRRDVCDIPLA 1680
+ ++ DI +A
Sbjct: 2044 EKNNLADILVA 2054
Score = 49.7 bits (117), Expect = 3e-05
Identities = 74/356 (20%), Positives = 149/356 (41%), Gaps = 41/356 (11%)
Query: 326 WYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGG 385
W+R+ + E + + L VD G E+V + + L E +P PC +W
Sbjct: 1737 WHRSKVEEKYVDDKVLVFL-VDCGIYEIVPVCNTKLLSNEIRNIPRQAVPCKW--IW--- 1790
Query: 386 RGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGED-----GINLNRVFGVQSC 440
+ S+ + L +N I F + V+ V + +D +NLN V
Sbjct: 1791 --FENSKNISFECLFADLEIN--ILFLKYLDAVWEVEILVDDLLLLEYLNLNTV------ 1840
Query: 441 CLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFVKNPS 500
V +++ E +S++P ++ + ++ + + Y V +PS
Sbjct: 1841 ----PVEENKLRLAEIVYNIESKTPVSSC----TIKSFTWVQFQNDRQYSGIATAVSDPS 1892
Query: 501 EFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWK-ENGYYRAIVTK 559
+F I+L L + + L + P C K+K E+ + R +++
Sbjct: 1893 DFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGSS--CLFKYKSEDQWNRVEISE 1950
Query: 560 LDDKSVDVFLVDRGNSENVDWYDV---RMLLPQFRQLPILAVKCTLADIWPL-GKTWSQE 615
+ +S+ + LVD G S + + ++ +++ + LP L+ C L I P GK WS+E
Sbjct: 1951 VSPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSEE 2010
Query: 616 AVSFFKKTVLHKELVIHILD-KQDHQYVIEILDESRTGEENISKVIAQAGYAKYQE 670
A FF+ + +LV + + + ++++ E + N++ ++ +G A Y +
Sbjct: 2011 AKIFFRDFLSKPDLVFQFREYHSETKLKVDVIHE----KNNLADILVASGLATYSK 2062
Score = 36.2 bits (82), Expect = 0.35
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Query: 313 PGSPCA-SCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCS---SLRYLLPEYFR 368
PGS C + W R + E PQ VL VDYG + S +L+ + E
Sbjct: 1929 PGSSCLFKYKSEDQWNRVEISEV-SPQSLCLVL-VDYGFSFYIRYSEIINLKVVPEELLN 1986
Query: 369 MPVVTYPCALYGLWDG-GRGWS 389
+P ++YPC LYG+ G+ WS
Sbjct: 1987 LPRLSYPCILYGILPAKGKHWS 2008
>gi|38505161 tudor domain containing 1 [Homo sapiens]
Length = 1189
Score = 134 bits (338), Expect = 7e-31
Identities = 172/696 (24%), Positives = 292/696 (41%), Gaps = 106/696 (15%)
Query: 471 EEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVT--FSKLMRRMCGFYSSAS 528
E I LRS++LK V K+P +F+++L V ++L + Y++
Sbjct: 248 ERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVH 307
Query: 529 KLDGVVLKPEPDDLCCVKWK-ENGYYRAIVTKLD--DKSVDVFLVDRGNSENVDWYDVRM 585
+ D + +K E +C K+ + + RAI+ +D K V +D GN E + +
Sbjct: 308 EKDYIPVKGE---VCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYH 364
Query: 586 LLPQFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEI 645
L P A+KC +A++ P WS + + K ++ + I I+D I
Sbjct: 365 LNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVD---------I 415
Query: 646 LDESRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESNKIPFAKTGE 705
L+E +V+ A + V + G + +H E +
Sbjct: 416 LEE---------EVVTFA-------------VEVELPNSGKLLDHVLIEMG---YGLKPS 450
Query: 706 GEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIKPGSSSK 765
G Q +K+EN S + + T N +VV + L+ L + G
Sbjct: 451 G-QDSKKENADQSDPEDVGKMTTENN----IVVDKS--------DLIPKVLTLNVGDEFC 497
Query: 766 GELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLA--- 822
G V++++ P F+CQ ++ + L L + + YC + P A
Sbjct: 498 GV----------VAHIQTPEDFFCQQLQSGRKLAELQASLSKYC-DQLPPRSDFYPAIGD 546
Query: 823 -CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFR 881
C A+ + + QW RA + S E V V +VDYG+ E++S+ + I + L++ QA +
Sbjct: 547 ICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIK 606
Query: 882 CSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNIVDLL 941
C L + +G +W +AI + + N K + +K + L N L ++D
Sbjct: 607 CVLAGVKPSLG----IWTPEAICLMKKLVQN---KIITVK-VVDKLE--NSSLVELIDKS 656
Query: 942 -TPFQSACHFLVEKRLA---------RPVKLQK---PLESSVQLHSYFYSTHDMKIGSEE 988
TP S L++ A +P +++ PL +++ ++ ++ +
Sbjct: 657 ETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTV 716
Query: 989 LVYITHIDDPWTFYCQLARNANI--LEQLSCSITQLSKVLLNLKTSPLNPGTLCLAKYT- 1045
V + I P FYC + + + L L+ S+ + + L G C A +
Sbjct: 717 DVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLP-NGFKAEIGQPCCAFFAG 775
Query: 1046 DGNWYRGIVIEKEPK---KVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSD 1102
DG+WYR +V E P KV FVD+GNI VT+D+L I S L LP Q +RC L+D
Sbjct: 776 DGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISS---TFLNLPFQGIRCQLAD 832
Query: 1103 IPD---HIPEEVVVWFQETILDKSLKALVVAKDPDG 1135
I H EE + FQ + L+A VV +G
Sbjct: 833 IQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENG 868
Score = 115 bits (288), Expect = 4e-25
Identities = 99/434 (22%), Positives = 196/434 (45%), Gaps = 31/434 (7%)
Query: 246 LQLGVTEAV--VITQVCHPHRIHCQLRS--VSQEIHRLSESMAQVYRGSTGTGDENSTSA 301
LQL T + +T+ HP + QL S V + +++LS S+ + Y A
Sbjct: 258 LQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETY-------------A 304
Query: 302 TWEEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRY 361
E++ P K A +D W RA++ Q+ A VL++DYG +E++ + + +
Sbjct: 305 NVHEKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYH 364
Query: 362 LLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYY- 420
L P C + + WS + K L++ + + KI E V +
Sbjct: 365 LNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFA 424
Query: 421 --VSLYGE----DGINLNRVFGVQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474
V L D + + +G++ + + + + ++ +PE + + + S
Sbjct: 425 VEVELPNSGKLLDHVLIEMGYGLKP---SGQDSKKENADQSDPEDVGKMTTENNIVVDKS 481
Query: 475 LPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVV 534
+ + L + + V ++ P +F+ + + ++L + +
Sbjct: 482 DLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFY 541
Query: 535 LKPEPDDLCCVKWKENG-YYRA-IVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQ 592
P D+CC ++ E+ +YRA ++ ++SV V VD GN E + + ++P+ +
Sbjct: 542 --PAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE 599
Query: 593 LPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTG 652
LP+ A+KC LA + P W+ EA+ KK V +K + + ++DK ++ ++E++D+S T
Sbjct: 600 LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETP 659
Query: 653 EENISKVIAQAGYA 666
++SKV+ AG+A
Sbjct: 660 HVSVSKVLLDAGFA 673
Score = 112 bits (280), Expect = 4e-24
Identities = 136/585 (23%), Positives = 235/585 (40%), Gaps = 73/585 (12%)
Query: 317 CASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPC 376
CA D WYRA +L + + V +VDYG E++S L ++P+ +P+ C
Sbjct: 549 CAQFSEDDQWYRASVL-AYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKC 607
Query: 377 ALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRVFG 436
L G+ W+ + +K L+ K + K+ E+ V L D V
Sbjct: 608 VLAGVKPSLGIWTPEAICLMKKLVQNKIITVKV--VDKLENSSLVELI--DKSETPHVSV 663
Query: 437 VQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFV 496
+ A + Q+ ++P + S V+ +++ + L ++ D V +
Sbjct: 664 SKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVI 723
Query: 497 KNPSEFWIRLRKHNVTFSKL--MRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YY 553
+P EF+ + K + KL + + + +G K E CC + +G +Y
Sbjct: 724 YSPGEFYCHVLKEDA-LKKLNDLNKSLAEHCQQKLPNG--FKAEIGQPCCAFFAGDGSWY 780
Query: 554 RAIVTK-LDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTW 612
RA+V + L + V V VD GN E V ++RM+ F LP ++C LADI K W
Sbjct: 781 RALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHW 840
Query: 613 SQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVIAQAGYAKYQEFE 672
S+EA++ F+ V +L +++ ++ +E+ D S IS V+
Sbjct: 841 SEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLID---------- 890
Query: 673 TKENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNG 732
E++++ + SP H ++++ V+K V
Sbjct: 891 --EHLVLKSASP-----HKDLPNDRL--------------------VNKHELQVHVQGLQ 923
Query: 733 STELVVQEKVKRASVYFPLMQNCLEIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLT 792
+T Q K V + N LEI + + Y G +
Sbjct: 924 ATSSAEQWKTIELPVDKTIQANVLEI---------------ISPNLFYALPKG-----MP 963
Query: 793 RNIQGLKTLMSDIQYYC---KNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVNV 849
N + L L +++ YC K+ R AC AK T + W RA++ G + V V
Sbjct: 964 ENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTD-VEV 1022
Query: 850 TFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQN 894
+ DYG+ E + + + I+ L + Q RCSL L++ G +
Sbjct: 1023 LYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSS 1067
Score = 98.2 bits (243), Expect = 7e-20
Identities = 131/623 (21%), Positives = 252/623 (40%), Gaps = 70/623 (11%)
Query: 70 GELCLVQVGL--LWHRCRVVSRQAQES-RVFLLDEGRTITAGAGSLAPGRREFFNLPSEV 126
G++C Q W+R V++ ++ES V +D G L P + LP +
Sbjct: 545 GDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQA 604
Query: 127 LGCVLAGLVPAGCGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLVLLEVPD 186
+ CVLAG+ P+ G W +A+ C++ L+ ++++ ++V D
Sbjct: 605 IKCVLAGVKPS-LGI--------WTPEAI-------------CLMKKLVQNKIITVKVVD 642
Query: 187 VFQQMRELGLARRVPD---SLFRSLLERYLTAATASVGSGVPV---LSRVPL--KQKQPG 238
+ + L + S+ + LL+ S+ + P + VPL + K
Sbjct: 643 KLENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNP 702
Query: 239 LDYFYPQLQLGVTEAVVITQVCHPHRIHCQL--RSVSQEIHRLSESMAQVYRGSTGTGDE 296
L++ + +L + T VV+ + P +C + ++++ L++S+A+ + G +
Sbjct: 703 LEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFK 762
Query: 297 NSTSATWEEREESPDKPGSPC-ASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVS 355
G PC A DG WYRAL+ E P +V VDYG E V+
Sbjct: 763 AEI--------------GQPCCAFFAGDGSWYRALVKEIL-PNGHVKVHFVDYGNIEEVT 807
Query: 356 CSSLRYLLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSF 415
LR + + +P C L + + WS + + + G + A++
Sbjct: 808 ADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTE- 866
Query: 416 EHVYYVSLYGEDGINLNRVF-GVQSCCLADR--VLQSQATEEEEP-----ETSQSQSPAE 467
+ G + +L+ + + S L D VL+S + ++ P + Q +
Sbjct: 867 ------NGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQ 920
Query: 468 EVDEEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGF--YS 525
+ S ++I L ++ A V + +P+ F+ + KL Y
Sbjct: 921 GLQATSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYC 980
Query: 526 SASKLDGVVLKPEPDDLCCVKW-KENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVR 584
+A K +P D CC K+ ++ +YRA+V D V+V D GN E + V+
Sbjct: 981 NAPK-SRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQ 1039
Query: 585 MLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIE 644
+ LP ++C+L + L + SQ + K +L++ +++ + + + +
Sbjct: 1040 PITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVS 1099
Query: 645 ILDESRTGEENISKVIAQAGYAK 667
+ S G +++ + G AK
Sbjct: 1100 VEKCSENGTVDVADKLVTFGLAK 1122
Score = 95.5 bits (236), Expect = 5e-19
Identities = 100/427 (23%), Positives = 188/427 (44%), Gaps = 55/427 (12%)
Query: 768 LEVGSTVEVR--VSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAP-HQRNTL--- 821
L++ T+E++ V+ ++PG F+ QL + + M+ + K T A H+++ +
Sbjct: 258 LQLKKTMEIKGTVTEFKHPGDFYVQLYSS--EVLEYMNQLSASLKETYANVHEKDYIPVK 315
Query: 822 --ACLAKRTVNRQWSRALISGIQ-SVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQ 878
C+AK TV++ W+RA+I + + +V ++DYG+ E++ + IY ++
Sbjct: 316 GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPC 375
Query: 879 AFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNI- 937
A +C + N+I G W I+A + +E C+I + + EE+
Sbjct: 376 AIKCFVANVIPAEGN----WSSDCIKATKPLL-------MEQYCSIKIVDILEEEVVTFA 424
Query: 938 --VDLLTPFQSACHFLVE-----KRLARPVKLQKPLESS--------------VQLHSYF 976
V+L + H L+E K + K + +S V
Sbjct: 425 VEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLI 484
Query: 977 YSTHDMKIGSEELVYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNP 1036
+ +G E + HI P F+CQ ++ L +L S+++ L
Sbjct: 485 PKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAI 544
Query: 1037 GTLCLAKYT-DGNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLP 1092
G +C A+++ D WYR V+ +E V +VD+GN +++ L PI +L LP
Sbjct: 545 GDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPI---IPKLLELP 601
Query: 1093 MQAVRCSLSDIPDHI---PEEVVVWFQETILDKSLKALVVAKDPDGTLIIELYGDNIQIS 1149
MQA++C L+ + + E + ++ + +K + VV K + +L +EL +
Sbjct: 602 MQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSL-VELIDKSETPH 660
Query: 1150 ASINKKL 1156
S++K L
Sbjct: 661 VSVSKVL 667
Score = 92.8 bits (229), Expect = 3e-18
Identities = 98/418 (23%), Positives = 178/418 (42%), Gaps = 23/418 (5%)
Query: 1311 VSHINDLSDFYVQLIEDEAEISHLSERLNS----VKTRPEYYVGPPLQRGDMICAVFPED 1366
V+HI DF+ Q ++ +++ L L+ + R ++Y P + GD+ CA F ED
Sbjct: 500 VAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFY--PAI--GDICCAQFSED 555
Query: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVP 1426
+ WYRA + + + V ++DYGN ++ ++ + LP I C L G +
Sbjct: 556 DQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPS 615
Query: 1427 DNKNSKKMMHYFSQRTSEAAIRCEFV-KFQDRWEVILADE----HGIIADDMI-SRYALS 1480
+ + + + I + V K ++ V L D+ H ++ ++ + +A+
Sbjct: 616 LGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVG 675
Query: 1481 EKSQVELSTQVIKSASSKSVNKSDIDTSVFLNWYNPE---KKMIRAYATVIDGPEYFWCQ 1537
E+S V +K S + ++ L W E + + VI P F+C
Sbjct: 676 EQSMVTDKPSDVKETSVPLGVEGKVNP---LEWTWVELGVDQTVDVVVCVIYSPGEFYCH 732
Query: 1538 FADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHYYRALITNICEDYL 1597
+ L+ L ++ E + IG PC + DG +YRAL+ I +
Sbjct: 733 VLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGH 792
Query: 1598 VSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEI 1657
V V VD+GNIE+ V L I S L++P Q C L+ S+E F
Sbjct: 793 VKVHFVDYGNIEE-VTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMC 851
Query: 1658 ITEDVLEITILEIRRDVCDIPLAIVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSE 1715
+ L+ ++E+ + I + + DL + I + +KSA P++++ ++
Sbjct: 852 VAGIKLQARVVEVTEN--GIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPND 907
Score = 85.9 bits (211), Expect = 4e-16
Identities = 112/421 (26%), Positives = 169/421 (40%), Gaps = 43/421 (10%)
Query: 711 KRENKTTSVSKALSDTTVVTNGSTELVVQEK--VKRASVYFPLMQNCLEIKPGSSSKGEL 768
K E SVSK L D G +V + VK SV + ++ P + EL
Sbjct: 655 KSETPHVSVSKVLLDAGFAV-GEQSMVTDKPSDVKETSVPLGVEG---KVNPLEWTWVEL 710
Query: 769 EVGSTVEVRVSYVENPGYFWCQLTRN--IQGLKTLMSDIQYYCKNTAAPHQRNTLA--CL 824
V TV+V V + +PG F+C + + ++ L L + +C+ + + C
Sbjct: 711 GVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCC 770
Query: 825 AKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSL 884
A + W RAL+ I HV V FVDYG+ E V+ + IS FL + Q RC L
Sbjct: 771 AFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQL 830
Query: 885 YNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASINEELFNI------- 937
+ IQ ++ W +AI F + L+ + I EL ++
Sbjct: 831 AD-IQSRNKH---WSEEAITRFQMCVAGI---KLQARVVEVTENGIGVELTDLSTCYPRI 883
Query: 938 -----VDLLTPFQSACHF--LVEKRLARPVKLQKPLESSVQLHSYF-YSTHDMKIGSEEL 989
+D +SA L RL +LQ ++ S + T ++ +
Sbjct: 884 ISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQ 943
Query: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTS--PLNP--GTLCLAKYT 1045
+ I P FY L + ++ C +T N S P P G C AKYT
Sbjct: 944 ANVLEIISPNLFYA-LPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYT 1002
Query: 1046 -DGNWYRGIVIEKEPK--KVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSD 1102
D WYR +V+ +V + D+GNI + + PI S L LP Q +RCSL
Sbjct: 1003 SDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSH---LALPFQIIRCSLEG 1059
Query: 1103 I 1103
+
Sbjct: 1060 L 1060
Score = 85.5 bits (210), Expect = 5e-16
Identities = 94/364 (25%), Positives = 147/364 (40%), Gaps = 36/364 (9%)
Query: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYV--GPPLQRGDMICAVFPED 1366
V V I +FY +++++A + L++ S+ + + G + G CA F D
Sbjct: 718 VVVCVIYSPGEFYCHVLKEDA-LKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGD 776
Query: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVP 1426
WYRA++KE PN + V F+DYGN+ V +++ + LP I C L +
Sbjct: 777 GSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQ-- 834
Query: 1427 DNKNSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVILADEHGIIADDMISRYALSEKSQVE 1486
+ H+ + + + +K Q R + + G+ D+ + Y +
Sbjct: 835 -----SRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLI 889
Query: 1487 LSTQVIKSAS-------SKSVNKSDID--------TSVFLNWYN---PEKKMIRAYATVI 1528
V+KSAS + VNK ++ TS W P K I+A I
Sbjct: 890 DEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQANVLEI 949
Query: 1529 DGPEYFWC----QFADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHY 1584
P F+ + EKL L E+ A + P IGD C +Y D +
Sbjct: 950 ISPNLFYALPKGMPENQEKLCMLTAELLEYCN--APKSRPPYRPRIGDACCAKYTSDDFW 1007
Query: 1585 YRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEG 1644
YRA++ D V V D+GNIE + + I S L++P Q C L G G
Sbjct: 1008 YRAVVLG-TSDTDVEVLYADYGNIE-TLPLCRVQPITSSHLALPFQIIRCSLEGLMELNG 1065
Query: 1645 LCSQ 1648
SQ
Sbjct: 1066 SSSQ 1069
Score = 82.8 bits (203), Expect = 3e-15
Identities = 93/384 (24%), Positives = 159/384 (41%), Gaps = 36/384 (9%)
Query: 1311 VSHINDLSDFYVQLIEDEA--EISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNL 1368
V+ DFYVQL E ++ LS L P+ +G++ A + D
Sbjct: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPV-KGEVCIAKYTVDQT 328
Query: 1369 WYRAVIKEQQPNDLLS-VQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQGFEVPD 1427
W RA+I+ + V +IDYGN ++ N+I L+ + P I C + +P
Sbjct: 329 WNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANV-IPA 387
Query: 1428 NKN------------------SKKMMHYFSQRTSEAAIRCEFV---KFQDRWEVILADEH 1466
N S K++ + A+ E K D V++ +
Sbjct: 388 EGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLD--HVLIEMGY 445
Query: 1467 GIIADDMISRYALSEKSQVELSTQVIKSASSKSVNKSDIDTSVFLNWYNPEKKMIRAYAT 1526
G+ S+ +++S E + + ++ V+KSD+ V E + A+
Sbjct: 446 GLKPSGQDSKKENADQSDPE-DVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCGVVAH-- 502
Query: 1527 VIDGPEYFWC-QFADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHYY 1585
I PE F+C Q KL L+ + +Q+ R + P IGD C ++ ED +Y
Sbjct: 503 -IQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPA--IGDICCAQFSEDDQWY 559
Query: 1586 RALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGL 1645
RA + + V V VD+GN E + L I +LL +PMQA C L+G S G+
Sbjct: 560 RASVLAYASEESVLVGYVDYGNFE-ILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGI 618
Query: 1646 CSQEGNDYFYEIITEDVLEITILE 1669
+ E +++ ++ + +++
Sbjct: 619 WTPEAICLMKKLVQNKIITVKVVD 642
Score = 41.2 bits (95), Expect = 0.011
Identities = 49/221 (22%), Positives = 90/221 (40%), Gaps = 7/221 (3%)
Query: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYRE 1580
I+ T P F+ Q +E L+ + + E A+ P G+ CI +Y
Sbjct: 266 IKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTV 325
Query: 1581 DGHYYRALITNI-CEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGF 1639
D + RA+I N+ + V +D+GN E+ + ++ + + P A C ++
Sbjct: 326 DQTWNRAIIQNVDVQQKKAHVLYIDYGN-EEIIPLNRIYHLNRNIDLFPPCAIKCFVANV 384
Query: 1640 NISEGLCSQEGNDYFYEIITEDVLEITILEIRRDVCDIPLAIVDLKSKGKSINEKMEKYS 1699
+EG S + ++ E I I++I + V+L + GK ++ + +
Sbjct: 385 IPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMG 444
Query: 1700 KTGIKSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNK 1740
G+K + DS+ + S DVG N V +K
Sbjct: 445 -YGLKPS----GQDSKKENADQSDPEDVGKMTTENNIVVDK 480
>gi|112293287 tudor domain containing 7 [Homo sapiens]
Length = 1098
Score = 74.3 bits (181), Expect = 1e-12
Identities = 128/598 (21%), Positives = 224/598 (37%), Gaps = 93/598 (15%)
Query: 326 WYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGG 385
W RA ++ T + +V +VDYG E V S L P++ + C L GL
Sbjct: 529 WLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLS 586
Query: 386 RGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRVFGVQSCCLADR 445
+V +++L GK +I V GED IN+N C D+
Sbjct: 587 DDPDLVKV--VESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAIC---DK 641
Query: 446 VLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFY-DAQVEFVKNPSEFWI 504
L+ + L+++A Y + +V + + +
Sbjct: 642 SLE--------------------------------VHLQVDAMYTNVKVTNICSDGTLYC 669
Query: 505 RLRKHNVT-FSKLMRRMCG-FYSSASKLDGVVLKPEPDDLCCVKWKENGYYRAIVTKLDD 562
++ + S L+R++ F+ + V P +C K I
Sbjct: 670 QVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLRVEITNVHSS 729
Query: 563 KSVDVFLVDRGNSENVDWYDVRMLLPQFRQ----LPILAVKCTLADIWPLGKTWSQEAVS 618
+++DV +D G +V ++R + P+F Q +P A+KC LAD+ W+ +AV
Sbjct: 730 RALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVL 789
Query: 619 FFKKTVLH-KELVIHILDKQDHQYVIEIL----DESRTGEENISKVIAQAGYAKYQEFET 673
+ + +VL+ + I + + + + + +I++ I A K+Q+
Sbjct: 790 WLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVF 849
Query: 674 KENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGS 733
I A SP + + N TGE +K N T + K++ D T S
Sbjct: 850 LSAISSGADSPNSKNGNMPMSGN------TGENFRK----NLTDVIKKSMVDHTSAF--S 897
Query: 734 TELVVQEKVKRASVYFPLMQNCLEIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTR 793
TE E+ P + G ++V V +PGYF Q +
Sbjct: 898 TE---------------------ELPPPVHLS---KPGEHMDVYVPVACHPGYFVIQPWQ 933
Query: 794 NIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVNVTFVD 853
I L+ LM ++ Y + H + V +W R L+ GI + V+V +D
Sbjct: 934 EIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELD 993
Query: 854 YGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFID 911
YG E+V+++ + + + F K+ QA L G W +A F ++
Sbjct: 994 YGKHELVNIRKVQPLVDMFRKLPFQAVTAQL------AGVKCNQWSEEASMVFRNHVE 1045
Score = 61.2 bits (147), Expect = 1e-08
Identities = 92/395 (23%), Positives = 163/395 (41%), Gaps = 66/395 (16%)
Query: 768 LEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDI--QYYCKNTA-APHQR-NTLAC 823
+E+ +T EV + YV ++ + LM D +YY KN P Q N
Sbjct: 470 VELSNTNEVVIRYVG----------KDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQL 519
Query: 824 LAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCS 883
LA W RA + + + V +VDYG E V Y ++ +F + QA +C
Sbjct: 520 LAVNAEEDAWLRAQVISTEE-NKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCK 578
Query: 884 LYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKC-TIFALASINEELFNIVDLLT 942
L L + + +P + VK +++ L C IFA+ +++ +V +L
Sbjct: 579 LAGL-EVLSDDPDL--VKVVES--------------LTCGKIFAVEILDKADIPLV-VLY 620
Query: 943 PFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFY 1002
+ + + K LE +Q+ + + + V +T+I T Y
Sbjct: 621 DTSGEDDININATCLKAI-CDKSLEVHLQVDAMYTN-----------VKVTNICSDGTLY 668
Query: 1003 CQL-ARNANILEQLSCSITQL-------SKVLLNLKTSPLNPGTLCLAKYTDGNWYRGIV 1054
CQ+ + N L L I S+ ++L G +CL + G W R +
Sbjct: 669 CQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFC----GKICLF-HCKGKWLRVEI 723
Query: 1055 IEKEPKK---VFFVDFGNIYVVTSDDLLPIPSD-AYDVLLLPMQAVRCSLSDIPDHI--- 1107
+ V F+D G + V +L IP +++ +P QA++C L+D+P I
Sbjct: 724 TNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMW 783
Query: 1108 PEEVVVWFQETILDKSLKALVVAKDPDGTLIIELY 1142
+ V+W ++++L+ S ++ V K + I +Y
Sbjct: 784 TPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVY 818
Score = 49.3 bits (116), Expect = 4e-05
Identities = 67/292 (22%), Positives = 112/292 (38%), Gaps = 33/292 (11%)
Query: 1359 ICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHC 1418
+ AV E++ W RA + + N + V ++DYG V +K +L+ L C
Sbjct: 519 LLAVNAEEDAWLRAQVISTEENKI-KVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKC 577
Query: 1419 SLQGFEVPDNKNSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVILADEHGIIADDM-ISRY 1477
L G EV + ++ T E + D V+L D G DD+ I+
Sbjct: 578 KLAGLEVLSD--DPDLVKVVESLTCGKIFAVEILDKADIPLVVLYDTSG--EDDININAT 633
Query: 1478 ALSEKSQVELSTQVIKSASSKSVNKSDIDTSVFLNWYNPEKKMIRAYATVIDGPEYFWCQ 1537
L L + A +V ++I + L P K + + + +YF C+
Sbjct: 634 CLKAICDKSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCK 693
Query: 1538 FADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHYYRALITNICEDYL 1597
+E C + P+ G C+ + G + R ITN+
Sbjct: 694 HMTSE---CF-----------------VSLPFCGKICLFHCK--GKWLRVEITNVHSSRA 731
Query: 1598 VSVRLVDFGNIEDCVDPKALWAIP----SELLSVPMQAFPCCLSGFNISEGL 1645
+ V+ +D G + V L IP E++++P QA CCL+ S G+
Sbjct: 732 LDVQFLDSGTVTS-VKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGM 782
Score = 48.1 bits (113), Expect = 9e-05
Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 9/195 (4%)
Query: 471 EEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRL--RKHNVTFSKLMRRMCGFYSSAS 528
E+I++P L + A V + N +E IR + ++ + M +YS
Sbjct: 450 EDITVPPLM---IPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNP 506
Query: 529 KLDGVVLKPEPDDLCCVKWKENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLP 588
K+ V L V +E+ + RA V ++ + V VD G SENV+ L P
Sbjct: 507 KITPVQAV-NVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKLNP 565
Query: 589 QFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDE 648
+F L A KC LA + L + V + K + ILDK D V+ + D
Sbjct: 566 KFCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLTCGKIFAVEILDKADIPLVV-LYDT 622
Query: 649 SRTGEENISKVIAQA 663
S + NI+ +A
Sbjct: 623 SGEDDININATCLKA 637
Score = 44.7 bits (104), Expect = 0.001
Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 13/167 (7%)
Query: 490 DAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKE 549
D V +P F I+ + LM M +YS + + V E D + K E
Sbjct: 915 DVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAV---EKDQVYAAK-VE 970
Query: 550 NGYYRAIVTK-LDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPL 608
N ++R ++ L + V V+ +D G E V+ V+ L+ FR+LP AV LA +
Sbjct: 971 NKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--K 1028
Query: 609 GKTWSQEAVSFFKKTVLHKEL------VIHILDKQDHQYVIEILDES 649
WS+EA F+ V K L VI + D + V+ ++D S
Sbjct: 1029 CNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTS 1075
Score = 40.8 bits (94), Expect = 0.014
Identities = 41/179 (22%), Positives = 78/179 (43%), Gaps = 23/179 (12%)
Query: 755 CLEIKPGSSSKGELEVGST-VEVRVSYVENPGYFWCQLT-RNIQGLKTLMSDIQ--YYCK 810
CL+ S + L+V + V+V+ + + G +CQ+ + + L L+ I+ ++CK
Sbjct: 634 CLKAICDKSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCK 693
Query: 811 NTAAPHQRNTLAC--LAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSI 868
+ + + C + +W R I+ + S ++V F+D G V V + I
Sbjct: 694 HMTSECFVSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREI 753
Query: 869 SEEFLK----VKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCT 923
FL+ + QA +C L +L Q +G +W A+ W ++ L C+
Sbjct: 754 PPRFLQEMIAIPPQAIKCCLADLPQSIG----MWTPDAV---------LWLRDSVLNCS 799
Score = 32.3 bits (72), Expect = 5.0
Identities = 18/57 (31%), Positives = 29/57 (50%)
Query: 1366 DNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQG 1422
+N W+R ++K N L+SV +DYG +V+ K+ L + LP + L G
Sbjct: 970 ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAG 1026
Score = 31.6 bits (70), Expect = 8.5
Identities = 34/131 (25%), Positives = 53/131 (40%), Gaps = 22/131 (16%)
Query: 254 VVITQVCHPHRIHCQLRSVSQEIHRLS---ESMAQVYRGSTGTGDENSTSATWEEREESP 310
V + CHP Q QEIH+L E M Y S EER +
Sbjct: 916 VYVPVACHPGYFVIQ---PWQEIHKLEVLMEEMILYYSVS-------------EERHIAV 959
Query: 311 DKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMP 370
+K A ++ W+R +LL+ V +DYG+ ELV+ ++ L+ + ++P
Sbjct: 960 EKDQVYAAK--VENKWHR-VLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLP 1016
Query: 371 VVTYPCALYGL 381
L G+
Sbjct: 1017 FQAVTAQLAGV 1027
>gi|40255178 tudor domain containing 5 [Homo sapiens]
Length = 981
Score = 68.9 bits (167), Expect = 5e-11
Identities = 61/210 (29%), Positives = 101/210 (48%), Gaps = 11/210 (5%)
Query: 493 VEFVKNPSEFWIRL--RKHNVTFSKLMRRMCGFYSSASKLDGVVLKP---EPDDLCCVKW 547
VE++ +PS+F+IR+ R + +M M YS+ D V+ +P LCCV+
Sbjct: 477 VEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRI 536
Query: 548 KENGY-YRAIVTK-LDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADI 605
E+ + YR I+ + L+ + V+VF D GN V +R L + +LP A+ C+LA +
Sbjct: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWV 596
Query: 606 WPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVIAQAGY 665
P+ + W+ +A+ F+K K LV + + D I + D S + V+ G+
Sbjct: 597 RPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGH 656
Query: 666 AKYQEFETKENILVNAHSPGHVSNHFTTES 695
A +ENI S + +TT S
Sbjct: 657 A----IVCRENISSKGFSELNPLALYTTSS 682
Score = 52.4 bits (124), Expect = 5e-06
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 22/168 (13%)
Query: 990 VYITHIDDPWTFYCQL-ARNAN------ILEQLSCSITQLSKVLLNLKTSPLNPGTLCLA 1042
V++ +I P FY ++ +R+++ ++E C QL + + PG LC
Sbjct: 475 VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
Query: 1043 KYTDGNWYRGIVI----EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRC 1098
+ ++ W+ ++I EK+ +VF+ DFGNI +V L + LP QA+ C
Sbjct: 535 RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKC---CYTKLPAQAIPC 591
Query: 1099 SLS---DIPDHIPEEVVVWFQETILDKSLKALVVAKDP--DGTLIIEL 1141
SL+ + +H + ++ FQ+ LK LV D DG L I L
Sbjct: 592 SLAWVRPVEEHWTSKAILQFQKLC---GLKPLVGVVDEYVDGILNIFL 636
Score = 49.3 bits (116), Expect = 4e-05
Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 16/141 (11%)
Query: 1309 VYVSHINDLSDFYV--------QLIED---EAEISHLSERLNSVKTRPEYYVGPPLQRGD 1357
V+V +I S FY+ +L+ED E + ++ ++ PE ++ P G
Sbjct: 475 VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQP----GH 530
Query: 1358 MICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIH 1417
+ C ED WYR +I + V + D+GN+ +V + + L LP I
Sbjct: 531 LCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIP 590
Query: 1418 CSLQGFE-VPDNKNSKKMMHY 1437
CSL V ++ SK ++ +
Sbjct: 591 CSLAWVRPVEEHWTSKAILQF 611
Score = 44.7 bits (104), Expect = 0.001
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 7/124 (5%)
Query: 1520 MIRAYATVIDGPEYFWCQFADTEKLQCLE---VEVQTA-GEQVADRRNCIPCPYI--GDP 1573
+I + I P F+ + + + LE +E++ Q+ R +P +I G
Sbjct: 472 LIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHL 531
Query: 1574 CIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFP 1633
C VR ED +YR +I + E V V DFGNI V +L + +P QA P
Sbjct: 532 CCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNI-GIVQKSSLRFLKCCYTKLPAQAIP 590
Query: 1634 CCLS 1637
C L+
Sbjct: 591 CSLA 594
Score = 41.6 bits (96), Expect = 0.008
Identities = 36/166 (21%), Positives = 65/166 (39%), Gaps = 6/166 (3%)
Query: 317 CASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPC 376
C D WYR ++ Q +V + D+G +V SSLR+L Y ++P PC
Sbjct: 533 CVRISEDKWWYRVIIHRVLEKQE-VEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPC 591
Query: 377 ALYGLWDGGRGWSRSQVGDLKTLI-LGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRVF 435
+L + W+ + + L L V E+ +++ + + + V
Sbjct: 592 SLAWVRPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVL 651
Query: 436 GVQSCCLADRV-LQSQATEEEEP---ETSQSQSPAEEVDEEISLPA 477
+ + R + S+ E P T+ S P + V E+ P+
Sbjct: 652 RTEGHAIVCRENISSKGFSELNPLALYTTSSGGPEDIVLTELGYPS 697
Score = 40.4 bits (93), Expect = 0.018
Identities = 35/151 (23%), Positives = 67/151 (44%), Gaps = 14/151 (9%)
Query: 768 LEVGSTVEVRVSYVENPGYFWCQL-TRNIQGLKTLMSDIQYYCKNTAAPHQRNTLA---- 822
L+ S + V V Y+ +P F+ ++ +R+ L M C + R +
Sbjct: 467 LDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFI 526
Query: 823 -----CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKA 877
C + + ++ W R +I + + V V + D+G+ +V ++ + + K+ A
Sbjct: 527 QPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPA 586
Query: 878 QAFRCSLYNLIQPVGQNPFVWDVKAIQAFNE 908
QA CSL ++PV ++ W KAI F +
Sbjct: 587 QAIPCSL-AWVRPVEEH---WTSKAILQFQK 613
>gi|94421471 ring finger protein 17 [Homo sapiens]
Length = 1623
Score = 68.9 bits (167), Expect = 5e-11
Identities = 125/524 (23%), Positives = 211/524 (40%), Gaps = 96/524 (18%)
Query: 767 ELEVGSTVE-VRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLA 825
E V S+ E V VS+V +P +F+ + I+ K L + +C ++ + L A
Sbjct: 409 EDNVESSAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGA 468
Query: 826 KRTV----NRQWSRALISGIQSVEHVN-------------------VTFVDYGDREMV-- 860
+ V N W R I+ + +E N + VD+G+ E++
Sbjct: 469 RIFVSSIKNGMWCRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFMVDFGNSEVLIV 528
Query: 861 ------------SVKNIYSISEEFLKV-KAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFN 907
S K ++++ L + K++ + L IQP+ Q + D+ Q N
Sbjct: 529 TGVVDTHVRPEHSAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIVP-QNSN 587
Query: 908 EFIDNAWQKNLELK-CTIFALASINEELFN------IVDLLTP------------FQSAC 948
E W++ +++ + +++ ++F IVDL P + A
Sbjct: 588 E----GWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIVDLQKPPPNKISSDMPVSLRDAL 643
Query: 949 HFLVEKRLARPVKLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFYCQLARN 1008
F+ E + L+ E + LH ++ K ++ V + HI+ P FY QL
Sbjct: 644 VFM-ELAKFKSQSLRSHFEKNTTLH--YHPPILPKEMTDVSVTVCHINSPGDFYLQLIEG 700
Query: 1009 ANILEQLSCSITQLSKVLLNLKTSPLNP--GTLCLAKYTDGNWYRGIVI---EKEPKKVF 1063
+IL L +I + K L P C+AK+ DG WYR VI + +V
Sbjct: 701 LDILFLLK-TIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVK 759
Query: 1064 FVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDIPDHIPEEVVVW-------FQ 1116
+VDFGN +T D+ I + L P +A++C L+ I + + + W F+
Sbjct: 760 YVDFGNTAKITIKDVRKIKD---EFLNAPEKAIKCKLAYIEPY--KRTMQWSKEAKEKFE 814
Query: 1117 ETILDKSLKALVVAKDPDGTLIIELY---GDNIQISASINKKL---GLLSY------KDR 1164
E DK + V+ D L++EL+ G + SIN +L GL SY KD
Sbjct: 815 EKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGLASYEIGYILKDN 874
Query: 1165 IRKKESEVLCSTTETLEEKNENMKLPCTEYLSKSVGYKLPNKEI 1208
+K S E + + N+ + L L NKE+
Sbjct: 875 SQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKEL 918
Score = 68.6 bits (166), Expect = 6e-11
Identities = 72/304 (23%), Positives = 133/304 (43%), Gaps = 21/304 (6%)
Query: 375 PCALYGL--WDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLN 432
PC+L + + GW + ++ KAV+ K+ + + V V L N
Sbjct: 575 PCSLKDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKV--FREEDGVLIVDLQKPPP---N 629
Query: 433 RVFGVQSCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFYDAQ 492
++ L D ++ + + +SQS ++ +L I K
Sbjct: 630 KISSDMPVSLRDALVFMELAK------FKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVT 683
Query: 493 VEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENGY 552
V + +P +F+++L + + L++ + FY S + +L P D C K+++ +
Sbjct: 684 VCHINSPGDFYLQLIE-GLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIW 742
Query: 553 YRAIVTKLDD-KSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKT 611
YRA V L + V+V VD GN+ + DVR + +F P A+KC LA I P +T
Sbjct: 743 YRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRT 802
Query: 612 --WSQEAVSFFKKTVLHKELVIHILD-KQDHQYVIEILDESRTGE---ENISKVIAQAGY 665
WS+EA F++ K + ++ +D+ ++E+ D E +I+ + + G
Sbjct: 803 MQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGL 862
Query: 666 AKYQ 669
A Y+
Sbjct: 863 ASYE 866
Score = 62.8 bits (151), Expect = 3e-09
Identities = 86/365 (23%), Positives = 149/365 (40%), Gaps = 51/365 (13%)
Query: 1308 TVYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFP--- 1364
+V V HIN DFY+QLIE + L +KT E+Y + +++C V
Sbjct: 681 SVTVCHINSPGDFYLQLIEG-------LDILFLLKTIEEFYKSEDGENLEILCPVQDQAC 733
Query: 1365 ----EDNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRL--DLVNAILPGLCIHC 1418
ED +WYRA + + + V+++D+GN + + + ++ + +NA P I C
Sbjct: 734 VAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNA--PEKAIKC 791
Query: 1419 SLQGFEVPDNKN---SKKMMHYFSQRTSEAAIRCEFVKFQDRWEVI--LADEHGI----- 1468
L E P + SK+ F ++ + + C +K + ++ L D G
Sbjct: 792 KLAYIE-PYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTT 850
Query: 1469 --IADDMISR--------YALSEKSQVEL-----STQVIKSASSKSVNKSDIDTSVFLNW 1513
I D ++ Y L + SQ + S + I S ++N + N+
Sbjct: 851 TSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENF 910
Query: 1514 YNPEKKMIRAYATVIDGPEYFWCQFADTEK-LQCLEVEVQTAGEQVADRRNCIPCPYIGD 1572
+ K + + + PE + Q+ TE L LE ++ A E P + D
Sbjct: 911 QSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYE----NSKWEPVKWEND 966
Query: 1573 -PCIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQA 1631
C V+ ++ + R I + D LV V L D G +E V+ L + L ++ +
Sbjct: 967 MHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVG-VELVVNVDCLRKLEENLKTMGRLS 1025
Query: 1632 FPCCL 1636
C L
Sbjct: 1026 LECSL 1030
Score = 56.6 bits (135), Expect = 2e-07
Identities = 198/953 (20%), Positives = 340/953 (35%), Gaps = 149/953 (15%)
Query: 234 QKQPGLDYFYPQLQLGVTEAVVITQVCH---PHRIHCQLRSVSQEIHRLSESMAQVYRGS 290
+K L Y P L +T+ V VCH P + QL +I L +++ + Y+
Sbjct: 661 EKNTTLHYHPPILPKEMTDVSVT--VCHINSPGDFYLQLIE-GLDILFLLKTIEEFYKSE 717
Query: 291 TGTGDENSTSATWEEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGR 350
G E E C + DG WYRA ++ Q +V +VD+G
Sbjct: 718 DG-----------ENLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQE-VEVKYVDFGN 765
Query: 351 KELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGGRG--WSRSQVGDLKTLILGKAVNAK 408
++ +R + E+ P C L + R WS+ + K +
Sbjct: 766 TAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCS 825
Query: 409 IEFYCSFEHVYYVSLYGEDGINLNRVFGVQSCCLADRVLQSQATEEEEPETSQSQ----- 463
+ ++V V L+ G + L L S + SQ
Sbjct: 826 VIKILE-DNVLLVELFDSLGAPEMTTTSINDQ-LVKEGLASYEIGYILKDNSQKHIEVWD 883
Query: 464 -SPAEEVDEEI---------SLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTF 513
SP E + E+ SLP + + N + V +P + +++
Sbjct: 884 PSPEEIISNEVHNLNPVSAKSLPN-ENFQSLYNKELPVHICNVISPEKIYVQWLLTENLL 942
Query: 514 SKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENGYYRA--IVTKLDDKSVDVFLVD 571
+ L +M Y + SK + V K E D C VK ++ +R I+ + D V+V L D
Sbjct: 943 NSLEEKMIAAYEN-SKWEPV--KWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999
Query: 572 RGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKT--WSQEAVSFFKKTVLHKEL 629
G V+ +R L + + L+++C+L DI P G + W+ A +
Sbjct: 1000 VGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVA 1059
Query: 630 VIHI-LDKQDHQYV----IEILDESRTGEE-NISKVIAQAGYAKYQEFETKENILVNAHS 683
I + +D +++ ++I GE ++SK + + G A E + N L N+HS
Sbjct: 1060 TIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALR---ERRINNLDNSHS 1116
Query: 684 PGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVK 743
+ +S ++P E + + V+ + + +++ ++KV
Sbjct: 1117 -------LSEKSLEVPL------------EQEDSVVTNCIKTNFDPDKKTADIISEQKVS 1157
Query: 744 RASVYFPLMQNCLEIKPGSSSKGELEVGSTV-EVRVSYVENPGYFWCQLTRNIQGLKTLM 802
+ LE + K V E VS V + G + + L +
Sbjct: 1158 E------FQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMT 1211
Query: 803 SDIQ--YYCKNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMV 860
++IQ C P+ A R + W R + + V V ++D+G E +
Sbjct: 1212 NEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGA-VRVQYLDHGFTEKI 1270
Query: 861 SVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLEL 920
++Y I + + C L+N PVG VW AI+ + + ++
Sbjct: 1271 PQCHLYPILL-YPDIPQFCIPCQLHNTT-PVGN---VWQPDAIEVLQQLLSKR-----QV 1320
Query: 921 KCTIFALASINEELFNIVDLLTPFQSACHFLVEKRLARPVKLQKPLESSVQL-HSYFYST 979
I L E +I L S +F+ + ++ L+ + H Y
Sbjct: 1321 DIHIMELPKNPWEKLSI-HLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEE 1379
Query: 980 HDMKIGSEEL--------------------------VYITHIDDPWTFYCQLARNANILE 1013
+I EEL V + H+ P Y L +
Sbjct: 1380 EQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQ 1439
Query: 1014 QLSCSITQLSKVL--------------LNLKTSPLNPGT------LCLAKYTDGNWYRGI 1053
S T S V +N K L P T CLA+Y DG WYR
Sbjct: 1440 SNQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAK 1499
Query: 1054 VI---EKEPKKVF--FVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLS 1101
++ E P + FVD+G+ +T + L IPS ++ P +A++ L+
Sbjct: 1500 IVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPS---HLMRYPARAIKVLLA 1549
Score = 52.4 bits (124), Expect = 5e-06
Identities = 59/220 (26%), Positives = 88/220 (40%), Gaps = 31/220 (14%)
Query: 1254 TTEKKEEISAETPLKT--ARVEATLSERKIGD--SCDKDLPLKFCEFPQKTIMPGFKTTV 1309
T+E EE+ E P + E E + + S + D PL PG V
Sbjct: 1357 TSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAV 1416
Query: 1310 YVSHINDLSDFYVQL-------------------IEDEAEISHLSERLNSVKTRPEYYVG 1350
V H+ ++ Y+ L + E+E L E L V + E
Sbjct: 1417 QVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEAL-- 1474
Query: 1351 PPLQ--RGDMICAVFPEDNLWYRA---VIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLD 1405
PPL R +M C +D LWYRA IKE P +L VQF+DYG+ + + N++ ++
Sbjct: 1475 PPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSIL-VQFVDYGSTAKLTLNRLCQIP 1533
Query: 1406 LVNAILPGLCIHCSLQGFEVPDNKNSKKMMHYFSQRTSEA 1445
P I L GF+ P + + Y + + EA
Sbjct: 1534 SHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEA 1573
Score = 50.4 bits (119), Expect = 2e-05
Identities = 80/349 (22%), Positives = 133/349 (38%), Gaps = 47/349 (13%)
Query: 312 KPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPV 371
K G CA G D WYR ++E +V ++D+G E + L Y + Y +P
Sbjct: 1230 KKGEACAVRGSDTLWYRGKVMEVVGG--AVRVQYLDHGFTEKIPQCHL-YPILLYPDIPQ 1286
Query: 372 VTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKI-EFYCSFEHVYYVSLYGEDGIN 430
PC L+ G W + L+ L+ + V+ I E + + LY DG++
Sbjct: 1287 FCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPWEKLSIHLYF-DGMS 1345
Query: 431 LNRVFGVQSCCLADRVLQ----------SQATEEEEPETSQSQSPAEEVDEEISLPALRS 480
L+ C ++ + + EEE+ E + + E D + P L S
Sbjct: 1346 LSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSS 1405
Query: 481 IRLKMNAFYDAQVEFVKNPSEFWIRL---------RKHNVTFSKLMRRMCGFYSSASKLD 531
Y QV+ V +P+E +I L +H+ T + S L
Sbjct: 1406 SLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQ 1465
Query: 532 GVVLKPE---------PDDLCCVKWKENGYYRA---IVTKLDDKSVDVFLVDRGNSENVD 579
V K E + C ++ + +YRA + + + S+ V VD G++ +
Sbjct: 1466 RVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLT 1525
Query: 580 WYDVRMLLPQFRQLPILAVKCTLADIWP----LGKT-------WSQEAV 617
+ + + P A+K LA P LG+T WS EA+
Sbjct: 1526 LNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEAL 1574
Score = 50.1 bits (118), Expect = 2e-05
Identities = 166/876 (18%), Positives = 312/876 (35%), Gaps = 125/876 (14%)
Query: 80 LWHRCRVVSRQA-QESRVFLLDEGRTITAGAGSLAPGRREFFNLPSEVLGCVLAGLVPAG 138
+W+R +V+ QE V +D G T + + EF N P + + C LA + P
Sbjct: 741 IWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPY- 799
Query: 139 CGAGSGEPPQHWPADAVDFLSNLQGKEVHGCVLDVLLLHRLVLLEVPD-----------V 187
+ W +A + + C + +L ++L+E+ D +
Sbjct: 800 ------KRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSI 853
Query: 188 FQQMRELGLARRVPDSLFRSLLERYLTAATAS----VGSGVPVLSRVPLKQKQPGLDYFY 243
Q+ + GLA + + ++++ S + + V L+ V K P ++
Sbjct: 854 NDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSL-PNENF-- 910
Query: 244 PQLQLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDENSTSATW 303
Q V I V P +I+ Q ++ L E M Y S W
Sbjct: 911 -QSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSK-----------W 958
Query: 304 EEREESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLL 363
E + D CA D + +R + +VL D G + +V+ LR L
Sbjct: 959 EPVKWENDMH---CAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLE 1015
Query: 364 PEYFRMPVVTYPCALYGLWDGGRG--WSRSQVGDLKTLILGKAVNA-------------- 407
M ++ C+L + G W+ + L + G
Sbjct: 1016 ENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWP 1075
Query: 408 -KIEFYCSFEHVYYVSLYG---EDGINLN--RVFGVQ-SCCLADRVLQSQATEEEEPETS 460
++ +C E V + + G+ L R+ + S L+++ L+ +E+ T+
Sbjct: 1076 LPVKIFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTN 1135
Query: 461 Q---------------SQSPAEEVDEEISLPALRSIR-------LKMNAFYDAQVEFVKN 498
S+ E E+I P R+ R MN F +A V V +
Sbjct: 1136 CIKTNFDPDKKTADIISEQKVSEFQEKILEP--RTTRGYKPPAIPNMNVF-EATVSCVGD 1192
Query: 499 PSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENGYYRAIVT 558
++ + K+ + L+ K + C V+ + +YR V
Sbjct: 1193 DGTIFVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKK--GEACAVRGSDTLWYRGKVM 1250
Query: 559 KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618
++ +V V +D G +E + + +L + +P + C L + P+G W +A+
Sbjct: 1251 EVVGGAVRVQYLDHGFTEKIPQCHLYPIL-LYPDIPQFCIPCQLHNTTPVGNVWQPDAIE 1309
Query: 619 FFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVIAQAGYAKYQEFETKENIL 678
++ + +++ IHI++ + + + G ++S +A Y KY E E +L
Sbjct: 1310 VLQQLLSKRQVDIHIMELPKNPWEKLSIHLYFDG-MSLSYFMA---YYKYCTSEHTEEML 1365
Query: 679 VNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVV 738
H + E +I F E+ E T + LS + + V
Sbjct: 1366 KEKPRSDH-DKKYEEEQWEIRF------EELLSAETDTPLLPPYLSSSLPSPGELYAVQV 1418
Query: 739 QEKVKRASVYFPLMQNCLE-IKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQG 797
+ V VY CL+ I+ + S + + S E+ ++ + ++
Sbjct: 1419 KHVVSPNEVYI-----CLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEA 1473
Query: 798 LKTLMSDIQYYCKNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVN--VTFVDYG 855
L L R + CLA+ + W RA I I+ ++ V FVDYG
Sbjct: 1474 LPPLTD-------------FRTEMPCLAEYD-DGLWYRAKIVAIKEFNPLSILVQFVDYG 1519
Query: 856 DREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPV 891
+++ + I ++ A+A + L P+
Sbjct: 1520 STAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPL 1555
Score = 41.6 bits (96), Expect = 0.008
Identities = 93/424 (21%), Positives = 163/424 (38%), Gaps = 70/424 (16%)
Query: 1268 KTARVEATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKT-TVYVSHINDLSDFYVQLIE 1326
KTA + +SE+K+ + +K L + + +P VS + D +V
Sbjct: 1146 KTADI---ISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKL 1202
Query: 1327 DEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQ 1386
E E+ ++ + S + + P + CAV D LWYR + E + VQ
Sbjct: 1203 SEFELIKMTNEIQS-NLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVV-GGAVRVQ 1260
Query: 1387 FIDYGNVSVVHTNKIGRLDLVNAIL----PGLCIHCSLQGFEVPDNKNSKKMMHYFSQRT 1442
++D+G T KI + L +L P CI C L N + Q
Sbjct: 1261 YLDHG-----FTEKIPQCHLYPILLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLL 1315
Query: 1443 SEAAIRCEFVKF-QDRWEVILADEH--GIIADDMIS--RYALSEKSQVELSTQVIKSASS 1497
S+ + ++ ++ WE + + G+ ++ +Y SE ++ L +
Sbjct: 1316 SKRQVDIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDK 1375
Query: 1498 K-----------SVNKSDIDTSV---FLNWYNPEKKMIRAYAT--VIDGPEYFWC----- 1536
K + ++ DT + +L+ P + A V+ E + C
Sbjct: 1376 KYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIE 1435
Query: 1537 ------QFADTE--------KLQCLEVEVQTAGEQVADRRNCIPCPYIGD-----PCIVR 1577
Q +DT+ + + L+ +Q ++V P + D PC+
Sbjct: 1436 TSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVE------ALPPLTDFRTEMPCLAE 1489
Query: 1578 YREDGHYYRALITNICEDYLVS--VRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCC 1635
Y +DG +YRA I I E +S V+ VD+G+ + L IPS L+ P +A
Sbjct: 1490 Y-DDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAK-LTLNRLCQIPSHLMRYPARAIKVL 1547
Query: 1636 LSGF 1639
L+GF
Sbjct: 1548 LAGF 1551
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 64.7 bits (156), Expect = 9e-10
Identities = 48/184 (26%), Positives = 89/184 (48%), Gaps = 13/184 (7%)
Query: 446 VLQSQATEEEEPETSQSQSPAEEVDE----EISLPALRSIRLKMNAFYDAQVEFVKNPSE 501
V+ + + E+ + S +S A+ + E EI P + + + V ++P+
Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP---DFSFHADEYLEVYVSASEHPNH 320
Query: 502 FWIRL-RKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YYRA-IVT 558
FWI++ ++ KL+ M Y ++ D L D+ NG +YRA ++
Sbjct: 321 FWIQIVGSRSLQLDKLVNEMTQHYENSVPED---LTVHVGDIVAAPLPTNGSWYRARVLG 377
Query: 559 KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618
L++ ++D++ VD G++ + D+R L F LP A++C+LA I P G W +EA+
Sbjct: 378 TLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALD 437
Query: 619 FFKK 622
F +
Sbjct: 438 EFDR 441
Score = 58.9 bits (141), Expect = 5e-08
Identities = 46/164 (28%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 774 VEVRVSYVENPGYFWCQL--TRNIQGLKTLMSDIQYYCKNTAAP----HQRNTLACLAKR 827
+EV VS E+P +FW Q+ +R++Q L L++++ + +N+ H + +A A
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVA--APL 364
Query: 828 TVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNL 887
N W RA + G ++++ FVD+GD +K++ ++ +FL + QA CSL
Sbjct: 365 PTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR- 423
Query: 888 IQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN 931
I P G W+ +A+ F+ A K L K + + I+
Sbjct: 424 IAPSGDQ---WEEEALDEFDRLTHCADWKPLVAKISSYVQTGIS 464
Score = 53.9 bits (128), Expect = 2e-06
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Query: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIP---CPYIGDPCIVR 1577
+ Y + + P +FW Q + LQ ++ E N +P ++GD
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKL----VNEMTQHYENSVPEDLTVHVGDIVAAP 363
Query: 1578 YREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLS 1637
+G +YRA + E+ + + VDFG+ DC K L A+ S+ LS+P QA C L+
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDC-PLKDLRALRSDFLSLPFQAIECSLA 422
Query: 1638 GFNISEGLCSQEGNDYF 1654
S +E D F
Sbjct: 423 RIAPSGDQWEEEALDEF 439
Score = 41.2 bits (95), Expect = 0.011
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%)
Query: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPL--NPGTLCLAKY-TD 1046
VY++ + P F+ Q+ + ++ QL + ++++ N L + G + A T+
Sbjct: 310 VYVSASEHPNHFWIQIVGSRSL--QLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
Query: 1047 GNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDI 1103
G+WYR V+ E ++FVDFG+ DL + SD L LP QA+ CSL+ I
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD---FLSLPFQAIECSLARI 424
Score = 39.3 bits (90), Expect = 0.041
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Query: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPL--QRGDMICAVFPED 1366
VYVS + F++Q++ + L + +N + E V L GD++ A P +
Sbjct: 310 VYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
Query: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSL 1420
WYRA + N L + F+D+G+ + L LP I CSL
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
Score = 31.6 bits (70), Expect = 8.5
Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 5/156 (3%)
Query: 323 DGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLW 382
+G WYRA +L T + VD+G LR L ++ +P C+L +
Sbjct: 367 NGSWYRARVLGTLENGNL-DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425
Query: 383 DGGRGWSRSQVGDLKTLIL---GKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV-FGVQ 438
G W + + L K + AKI Y + +Y D N ++ G++
Sbjct: 426 PSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLE 485
Query: 439 SCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474
+ + EE + A E D +S
Sbjct: 486 LVHKGYAIELPEDIEENRAVPDMLKDMATETDASLS 521
>gi|145312246 tudor and KH domain containing isoform b [Homo
sapiens]
Length = 516
Score = 64.7 bits (156), Expect = 9e-10
Identities = 48/184 (26%), Positives = 89/184 (48%), Gaps = 13/184 (7%)
Query: 446 VLQSQATEEEEPETSQSQSPAEEVDE----EISLPALRSIRLKMNAFYDAQVEFVKNPSE 501
V+ + + E+ + S +S A+ + E EI P + + + V ++P+
Sbjct: 219 VVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP---DFSFHADEYLEVYVSASEHPNH 275
Query: 502 FWIRL-RKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YYRA-IVT 558
FWI++ ++ KL+ M Y ++ D L D+ NG +YRA ++
Sbjct: 276 FWIQIVGSRSLQLDKLVNEMTQHYENSVPED---LTVHVGDIVAAPLPTNGSWYRARVLG 332
Query: 559 KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618
L++ ++D++ VD G++ + D+R L F LP A++C+LA I P G W +EA+
Sbjct: 333 TLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALD 392
Query: 619 FFKK 622
F +
Sbjct: 393 EFDR 396
Score = 58.9 bits (141), Expect = 5e-08
Identities = 46/164 (28%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 774 VEVRVSYVENPGYFWCQL--TRNIQGLKTLMSDIQYYCKNTAAP----HQRNTLACLAKR 827
+EV VS E+P +FW Q+ +R++Q L L++++ + +N+ H + +A A
Sbjct: 263 LEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVA--APL 319
Query: 828 TVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNL 887
N W RA + G ++++ FVD+GD +K++ ++ +FL + QA CSL
Sbjct: 320 PTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR- 378
Query: 888 IQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN 931
I P G W+ +A+ F+ A K L K + + I+
Sbjct: 379 IAPSGDQ---WEEEALDEFDRLTHCADWKPLVAKISSYVQTGIS 419
Score = 53.9 bits (128), Expect = 2e-06
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Query: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIP---CPYIGDPCIVR 1577
+ Y + + P +FW Q + LQ ++ E N +P ++GD
Sbjct: 263 LEVYVSASEHPNHFWIQIVGSRSLQLDKL----VNEMTQHYENSVPEDLTVHVGDIVAAP 318
Query: 1578 YREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLS 1637
+G +YRA + E+ + + VDFG+ DC K L A+ S+ LS+P QA C L+
Sbjct: 319 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDC-PLKDLRALRSDFLSLPFQAIECSLA 377
Query: 1638 GFNISEGLCSQEGNDYF 1654
S +E D F
Sbjct: 378 RIAPSGDQWEEEALDEF 394
Score = 41.2 bits (95), Expect = 0.011
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%)
Query: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPL--NPGTLCLAKY-TD 1046
VY++ + P F+ Q+ + ++ QL + ++++ N L + G + A T+
Sbjct: 265 VYVSASEHPNHFWIQIVGSRSL--QLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 322
Query: 1047 GNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDI 1103
G+WYR V+ E ++FVDFG+ DL + SD L LP QA+ CSL+ I
Sbjct: 323 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD---FLSLPFQAIECSLARI 379
Score = 39.3 bits (90), Expect = 0.041
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Query: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPL--QRGDMICAVFPED 1366
VYVS + F++Q++ + L + +N + E V L GD++ A P +
Sbjct: 265 VYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 322
Query: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSL 1420
WYRA + N L + F+D+G+ + L LP I CSL
Sbjct: 323 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 376
Score = 31.6 bits (70), Expect = 8.5
Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 5/156 (3%)
Query: 323 DGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLW 382
+G WYRA +L T + VD+G LR L ++ +P C+L +
Sbjct: 322 NGSWYRARVLGTLENGNL-DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 380
Query: 383 DGGRGWSRSQVGDLKTLIL---GKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV-FGVQ 438
G W + + L K + AKI Y + +Y D N ++ G++
Sbjct: 381 PSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLE 440
Query: 439 SCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474
+ + EE + A E D +S
Sbjct: 441 LVHKGYAIELPEDIEENRAVPDMLKDMATETDASLS 476
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 64.7 bits (156), Expect = 9e-10
Identities = 48/184 (26%), Positives = 89/184 (48%), Gaps = 13/184 (7%)
Query: 446 VLQSQATEEEEPETSQSQSPAEEVDE----EISLPALRSIRLKMNAFYDAQVEFVKNPSE 501
V+ + + E+ + S +S A+ + E EI P + + + V ++P+
Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP---DFSFHADEYLEVYVSASEHPNH 320
Query: 502 FWIRL-RKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YYRA-IVT 558
FWI++ ++ KL+ M Y ++ D L D+ NG +YRA ++
Sbjct: 321 FWIQIVGSRSLQLDKLVNEMTQHYENSVPED---LTVHVGDIVAAPLPTNGSWYRARVLG 377
Query: 559 KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618
L++ ++D++ VD G++ + D+R L F LP A++C+LA I P G W +EA+
Sbjct: 378 TLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALD 437
Query: 619 FFKK 622
F +
Sbjct: 438 EFDR 441
Score = 58.9 bits (141), Expect = 5e-08
Identities = 46/164 (28%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 774 VEVRVSYVENPGYFWCQL--TRNIQGLKTLMSDIQYYCKNTAAP----HQRNTLACLAKR 827
+EV VS E+P +FW Q+ +R++Q L L++++ + +N+ H + +A A
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVA--APL 364
Query: 828 TVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNL 887
N W RA + G ++++ FVD+GD +K++ ++ +FL + QA CSL
Sbjct: 365 PTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR- 423
Query: 888 IQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN 931
I P G W+ +A+ F+ A K L K + + I+
Sbjct: 424 IAPSGDQ---WEEEALDEFDRLTHCADWKPLVAKISSYVQTGIS 464
Score = 53.9 bits (128), Expect = 2e-06
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Query: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIP---CPYIGDPCIVR 1577
+ Y + + P +FW Q + LQ ++ E N +P ++GD
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKL----VNEMTQHYENSVPEDLTVHVGDIVAAP 363
Query: 1578 YREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLS 1637
+G +YRA + E+ + + VDFG+ DC K L A+ S+ LS+P QA C L+
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDC-PLKDLRALRSDFLSLPFQAIECSLA 422
Query: 1638 GFNISEGLCSQEGNDYF 1654
S +E D F
Sbjct: 423 RIAPSGDQWEEEALDEF 439
Score = 41.2 bits (95), Expect = 0.011
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%)
Query: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPL--NPGTLCLAKY-TD 1046
VY++ + P F+ Q+ + ++ QL + ++++ N L + G + A T+
Sbjct: 310 VYVSASEHPNHFWIQIVGSRSL--QLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
Query: 1047 GNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDI 1103
G+WYR V+ E ++FVDFG+ DL + SD L LP QA+ CSL+ I
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD---FLSLPFQAIECSLARI 424
Score = 39.3 bits (90), Expect = 0.041
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Query: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPL--QRGDMICAVFPED 1366
VYVS + F++Q++ + L + +N + E V L GD++ A P +
Sbjct: 310 VYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
Query: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSL 1420
WYRA + N L + F+D+G+ + L LP I CSL
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
Score = 31.6 bits (70), Expect = 8.5
Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 5/156 (3%)
Query: 323 DGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLW 382
+G WYRA +L T + VD+G LR L ++ +P C+L +
Sbjct: 367 NGSWYRARVLGTLENGNL-DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425
Query: 383 DGGRGWSRSQVGDLKTLIL---GKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV-FGVQ 438
G W + + L K + AKI Y + +Y D N ++ G++
Sbjct: 426 PSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLE 485
Query: 439 SCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474
+ + EE + A E D +S
Sbjct: 486 LVHKGYAIELPEDIEENRAVPDMLKDMATETDASLS 521
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 64.7 bits (156), Expect = 9e-10
Identities = 48/184 (26%), Positives = 89/184 (48%), Gaps = 13/184 (7%)
Query: 446 VLQSQATEEEEPETSQSQSPAEEVDE----EISLPALRSIRLKMNAFYDAQVEFVKNPSE 501
V+ + + E+ + S +S A+ + E EI P + + + V ++P+
Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP---DFSFHADEYLEVYVSASEHPNH 320
Query: 502 FWIRL-RKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YYRA-IVT 558
FWI++ ++ KL+ M Y ++ D L D+ NG +YRA ++
Sbjct: 321 FWIQIVGSRSLQLDKLVNEMTQHYENSVPED---LTVHVGDIVAAPLPTNGSWYRARVLG 377
Query: 559 KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618
L++ ++D++ VD G++ + D+R L F LP A++C+LA I P G W +EA+
Sbjct: 378 TLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALD 437
Query: 619 FFKK 622
F +
Sbjct: 438 EFDR 441
Score = 58.9 bits (141), Expect = 5e-08
Identities = 46/164 (28%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 774 VEVRVSYVENPGYFWCQL--TRNIQGLKTLMSDIQYYCKNTAAP----HQRNTLACLAKR 827
+EV VS E+P +FW Q+ +R++Q L L++++ + +N+ H + +A A
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVA--APL 364
Query: 828 TVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNL 887
N W RA + G ++++ FVD+GD +K++ ++ +FL + QA CSL
Sbjct: 365 PTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR- 423
Query: 888 IQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN 931
I P G W+ +A+ F+ A K L K + + I+
Sbjct: 424 IAPSGDQ---WEEEALDEFDRLTHCADWKPLVAKISSYVQTGIS 464
Score = 53.9 bits (128), Expect = 2e-06
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Query: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIP---CPYIGDPCIVR 1577
+ Y + + P +FW Q + LQ ++ E N +P ++GD
Sbjct: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKL----VNEMTQHYENSVPEDLTVHVGDIVAAP 363
Query: 1578 YREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLS 1637
+G +YRA + E+ + + VDFG+ DC K L A+ S+ LS+P QA C L+
Sbjct: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDC-PLKDLRALRSDFLSLPFQAIECSLA 422
Query: 1638 GFNISEGLCSQEGNDYF 1654
S +E D F
Sbjct: 423 RIAPSGDQWEEEALDEF 439
Score = 41.2 bits (95), Expect = 0.011
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%)
Query: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPL--NPGTLCLAKY-TD 1046
VY++ + P F+ Q+ + ++ QL + ++++ N L + G + A T+
Sbjct: 310 VYVSASEHPNHFWIQIVGSRSL--QLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
Query: 1047 GNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDI 1103
G+WYR V+ E ++FVDFG+ DL + SD L LP QA+ CSL+ I
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD---FLSLPFQAIECSLARI 424
Score = 39.3 bits (90), Expect = 0.041
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Query: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPL--QRGDMICAVFPED 1366
VYVS + F++Q++ + L + +N + E V L GD++ A P +
Sbjct: 310 VYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
Query: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSL 1420
WYRA + N L + F+D+G+ + L LP I CSL
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
Score = 31.6 bits (70), Expect = 8.5
Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 5/156 (3%)
Query: 323 DGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLW 382
+G WYRA +L T + VD+G LR L ++ +P C+L +
Sbjct: 367 NGSWYRARVLGTLENGNL-DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425
Query: 383 DGGRGWSRSQVGDLKTLIL---GKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV-FGVQ 438
G W + + L K + AKI Y + +Y D N ++ G++
Sbjct: 426 PSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLE 485
Query: 439 SCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474
+ + EE + A E D +S
Sbjct: 486 LVHKGYAIELPEDIEENRAVPDMLKDMATETDASLS 521
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 56.2 bits (134), Expect = 3e-07
Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 12/152 (7%)
Query: 537 PEPDDLCCVKWKE---NGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQL 593
P PD +C + + Y+RA V + S +VF VD GN +VD + + + QF +L
Sbjct: 945 PHPDLVCLAPFADFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLEL 1004
Query: 594 PILAVKCTLADIWP------LGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILD 647
P A++ + + P GK WS A +F V L++ + +++
Sbjct: 1005 PFQALEFKICKMRPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQ 1064
Query: 648 ESRTGEE-NISKVIAQAGYAKYQE--FETKEN 676
S + NI V+ Q GYA+ E +E+K++
Sbjct: 1065 YSGVQDAINIRDVLIQQGYAELTEESYESKQS 1096
Score = 40.4 bits (93), Expect = 0.018
Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 11/94 (11%)
Query: 1008 NANILEQLSCSITQLSKVLLNLKTSPLNPGTLCLAKYTDGN---WYRGIV--IEKEPKKV 1062
N+ IL++L+ I QL+ L+ L T P +P +CLA + D + ++R V + +V
Sbjct: 922 NSEILKKLTAEINQLT--LVPLPTHP-HPDLVCLAPFADFDKQRYFRAQVLYVSGNSAEV 978
Query: 1063 FFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAV 1096
FFVD+GN V L+ IP L LP QA+
Sbjct: 979 FFVDYGNKSHVDLHLLMEIPC---QFLELPFQAL 1009
Score = 34.7 bits (78), Expect = 1.0
Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 756 LEIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLT--RNIQGLKTLMSDIQYYCKNTA 813
+++ +S + + + + V+ V G+FW N + LK L ++I
Sbjct: 882 MQVSFNTSDRSQTVTDLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQLTLVPL 941
Query: 814 APHQRNTLACLAKRTV--NRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEE 871
H L CLA +++ RA + + S V FVDYG++ V + + I +
Sbjct: 942 PTHPHPDLVCLAPFADFDKQRYFRAQVLYV-SGNSAEVFFVDYGNKSHVDLHLLMEIPCQ 1000
Query: 872 FLKVKAQA 879
FL++ QA
Sbjct: 1001 FLELPFQA 1008
>gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
Length = 1019
Score = 54.7 bits (130), Expect = 9e-07
Identities = 65/231 (28%), Positives = 99/231 (42%), Gaps = 37/231 (16%)
Query: 969 SVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFYCQ-LARNANILEQLSCSIT----QLS 1023
SV D E V +HI+D TF+ Q + RN +I+ ++ CS++ Q S
Sbjct: 15 SVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIM-KIGCSLSEVCPQAS 73
Query: 1024 KVLLNLKTSPLNPGTLCLAKYTDGNWYRGIV---IEKEPKKVFFVDFGNIYVVTSDDLLP 1080
VL NL + + G D WYR V I E V ++D+GN ++ D++
Sbjct: 74 SVLGNLDPNKIYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVE 129
Query: 1081 IPSDAYDVLLLPMQAVRCSLSDIPDHIP--EEVVVWFQET------ILDKSLKALVVAKD 1132
IP L L +V HIP +EV + Q T I +K +K + A
Sbjct: 130 IP------LELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATS 183
Query: 1133 PDGTLIIELYGDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETLEEK 1183
DGT+I + ++ I + KK + ++ R L S T+ EEK
Sbjct: 184 EDGTVIAQAEYGSVDIGEEVLKK----GFAEKCR------LASRTDICEEK 224
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 1312 SHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYR 1371
SHI D F+ Q I +I + L+ V + +G L + +F ED WYR
Sbjct: 39 SHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGN-LDPNKIYGGLFSEDQCWYR 97
Query: 1372 AVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDL 1406
+ + + V++IDYGN +++ + I + L
Sbjct: 98 CKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPL 132
Score = 33.1 bits (74), Expect = 2.9
Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 13/128 (10%)
Query: 779 SYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTV-------NR 831
S++E+ FW Q + + + + C P + L L + ++
Sbjct: 39 SHIEDAVTFWAQSINRNKDIMKIGCSLSEVC-----PQASSVLGNLDPNKIYGGLFSEDQ 93
Query: 832 QWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPV 891
W R + I SVE V ++DYG+ E+++ +I I E L+ + A + L+ L P
Sbjct: 94 CWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLE-LQFSSVAKKYKLWGLHIPS 152
Query: 892 GQNPFVWD 899
Q +D
Sbjct: 153 DQEVTQFD 160
>gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]
Length = 996
Score = 54.3 bits (129), Expect = 1e-06
Identities = 65/221 (29%), Positives = 100/221 (45%), Gaps = 40/221 (18%)
Query: 979 THDMKIGSEELVYITHIDDPWTFYCQ-LARNANILEQLSCSIT----QLSKVLLNLKTSP 1033
TH K+ E V +HI+D TF+ Q + RN +I++ + CS++ Q S VL NL +
Sbjct: 5 THYDKV---EDVVGSHIEDAVTFWAQSINRNKDIMK-IGCSLSEVCPQASSVLGNLDPNK 60
Query: 1034 LNPGTLCLAKYTDGNWYRGIV---IEKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLL 1090
+ G D WYR V I E V ++D+GN ++ D++ IP L
Sbjct: 61 IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIP------LE 110
Query: 1091 LPMQAVRCSLSDIPDHIP--EEVVVWFQET------ILDKSLKALVVAKDPDGTLIIELY 1142
L +V HIP +EV + Q T I +K +K + A DGT+I +
Sbjct: 111 LQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAE 170
Query: 1143 GDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETLEEK 1183
++ I + KK + ++ R L S T+ EEK
Sbjct: 171 YGSVDIGEEVLKK----GFAEKCR------LASRTDICEEK 201
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 1312 SHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYR 1371
SHI D F+ Q I +I + L+ V + +G L + +F ED WYR
Sbjct: 16 SHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGN-LDPNKIYGGLFSEDQCWYR 74
Query: 1372 AVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDL 1406
+ + + V++IDYGN +++ + I + L
Sbjct: 75 CKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPL 109
Score = 33.1 bits (74), Expect = 2.9
Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 13/128 (10%)
Query: 779 SYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTV-------NR 831
S++E+ FW Q + + + + C P + L L + ++
Sbjct: 16 SHIEDAVTFWAQSINRNKDIMKIGCSLSEVC-----PQASSVLGNLDPNKIYGGLFSEDQ 70
Query: 832 QWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPV 891
W R + I SVE V ++DYG+ E+++ +I I E L+ + A + L+ L P
Sbjct: 71 CWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLE-LQFSSVAKKYKLWGLHIPS 129
Query: 892 GQNPFVWD 899
Q +D
Sbjct: 130 DQEVTQFD 137
>gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]
Length = 996
Score = 54.3 bits (129), Expect = 1e-06
Identities = 65/221 (29%), Positives = 100/221 (45%), Gaps = 40/221 (18%)
Query: 979 THDMKIGSEELVYITHIDDPWTFYCQ-LARNANILEQLSCSIT----QLSKVLLNLKTSP 1033
TH K+ E V +HI+D TF+ Q + RN +I++ + CS++ Q S VL NL +
Sbjct: 5 THYDKV---EDVVGSHIEDAVTFWAQSINRNKDIMK-IGCSLSEVCPQASSVLGNLDPNK 60
Query: 1034 LNPGTLCLAKYTDGNWYRGIV---IEKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLL 1090
+ G D WYR V I E V ++D+GN ++ D++ IP L
Sbjct: 61 IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIP------LE 110
Query: 1091 LPMQAVRCSLSDIPDHIP--EEVVVWFQET------ILDKSLKALVVAKDPDGTLIIELY 1142
L +V HIP +EV + Q T I +K +K + A DGT+I +
Sbjct: 111 LQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAE 170
Query: 1143 GDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETLEEK 1183
++ I + KK + ++ R L S T+ EEK
Sbjct: 171 YGSVDIGEEVLKK----GFAEKCR------LASRTDICEEK 201
Score = 42.0 bits (97), Expect = 0.006
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 1312 SHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYR 1371
SHI D F+ Q I +I + L+ V + +G L + +F ED WYR
Sbjct: 16 SHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGN-LDPNKIYGGLFSEDQCWYR 74
Query: 1372 AVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDL 1406
+ + + V++IDYGN +++ + I + L
Sbjct: 75 CKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPL 109
Score = 33.1 bits (74), Expect = 2.9
Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 13/128 (10%)
Query: 779 SYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTV-------NR 831
S++E+ FW Q + + + + C P + L L + ++
Sbjct: 16 SHIEDAVTFWAQSINRNKDIMKIGCSLSEVC-----PQASSVLGNLDPNKIYGGLFSEDQ 70
Query: 832 QWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPV 891
W R + I SVE V ++DYG+ E+++ +I I E L+ + A + L+ L P
Sbjct: 71 CWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLE-LQFSSVAKKYKLWGLHIPS 129
Query: 892 GQNPFVWD 899
Q +D
Sbjct: 130 DQEVTQFD 137
>gi|77404397 staphylococcal nuclease domain containing 1 [Homo
sapiens]
Length = 910
Score = 53.5 bits (127), Expect = 2e-06
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 4/127 (3%)
Query: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERL-NSVKTRPEYYVGPPLQRGDMICAVFPEDN 1367
V+V+ I D FYVQ +E ++ L E + N + + P +RG+ A F D
Sbjct: 685 VFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFV-DG 743
Query: 1368 LWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLD--LVNAILPGLCIHCSLQGFEV 1425
WYRA +++ + + V +IDYGN V+ + ++G L +LP + +V
Sbjct: 744 EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQV 803
Query: 1426 PDNKNSK 1432
P + +++
Sbjct: 804 PQDDDAR 810
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/135 (30%), Positives = 63/135 (46%), Gaps = 27/135 (20%)
Query: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNP-----------GT 1038
V++T I D FY Q TQL K++ N++ + G
Sbjct: 685 VFVTEITDDLHFYVQDVETG----------TQLEKLMENMRNDIASHPPVEGSYAPRRGE 734
Query: 1039 LCLAKYTDGNWYRGIVIEKE-PKK--VFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQA 1095
C+AK+ DG WYR V + E P K VF++D+GN V+ S L + S A+ +LP QA
Sbjct: 735 FCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL-SPAFSTRVLPAQA 793
Query: 1096 VRCSLSDIPDHIPEE 1110
+ + I +P++
Sbjct: 794 TEYAFAFI--QVPQD 806
Score = 39.7 bits (91), Expect = 0.031
Identities = 54/244 (22%), Positives = 98/244 (40%), Gaps = 25/244 (10%)
Query: 378 LYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV--- 434
L GL G +S K L+L + V ++E + ++ DG NL+ +
Sbjct: 567 LPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGN--FIGWLHIDGANLSVLLVE 624
Query: 435 -------FGVQSCCLADRVLQSQATEEEEPE---TSQSQSPAEEVDEEISLPALRSIRLK 484
F + +L ++ +++ E + P EEV +P L + +
Sbjct: 625 HALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEV-----MPVLEE-KER 678
Query: 485 MNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCC 544
++ V + + F+++ + KLM M +S ++G P + C
Sbjct: 679 SASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYA-PRRGEFCI 737
Query: 545 VKWKENGYYRAIVTKLDDKS-VDVFLVDRGNSENVDWYDVRMLLPQF--RQLPILAVKCT 601
K+ + +YRA V K++ + + VF +D GN E + + L P F R LP A +
Sbjct: 738 AKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYA 797
Query: 602 LADI 605
A I
Sbjct: 798 FAFI 801
Score = 36.6 bits (83), Expect = 0.27
Identities = 16/50 (32%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 823 CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEF 872
C+AK V+ +W RA + ++S ++V ++DYG+RE++ + ++S F
Sbjct: 736 CIAK-FVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
Score = 35.0 bits (79), Expect = 0.77
Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 314 GSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEY 366
G C + +DG WYRA + + P + V ++DYG +E++ + L L P +
Sbjct: 733 GEFCIAKFVDGEWYRARVEKVESPAK-IHVFYIDYGNREVLPSTRLGTLSPAF 784
>gi|161016765 tudor domain containing 12 [Homo sapiens]
Length = 395
Score = 44.3 bits (103), Expect = 0.001
Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 33/156 (21%)
Query: 496 VKNPSEFWIRLR------KHNVTFSKLMRRMCGFYSSASKLDGVVLKP---EPDDLCCVK 546
+++P FW+ ++ H+V + KL M FY+S + + +KP E +C V
Sbjct: 9 IEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQ--DIEIKPLTLEEGQVCVVY 66
Query: 547 WKE-----NGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCT 601
+E ++I + D + FLVD + V ++R+++ F QLP A K +
Sbjct: 67 CEELKCWCRAIVKSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFS 126
Query: 602 L----------------ADIWPLGKTWSQEAVSFFK 621
L DI P K W A+ +F+
Sbjct: 127 LYCTKPVTLHIDFCRDSTDIVP-AKKWDNAAIQYFQ 161
Score = 32.7 bits (73), Expect = 3.8
Identities = 47/213 (22%), Positives = 78/213 (36%), Gaps = 42/213 (19%)
Query: 774 VEVRVSYVENPGYFWCQLTRNIQGLKTLMS-DIQYYCKNTAAPHQRNTLA---------- 822
+++ V +E+PG FW I+G + D+ Y N+A N+
Sbjct: 2 LQLLVLKIEDPGCFWVI----IKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTL 57
Query: 823 -----CLAKRTVNRQWSRALISGIQSVEHVNVT---FVDYGDREMVSVKNIYSISEEFLK 874
C+ + W RA++ I S + VD+ V KNI + E F++
Sbjct: 58 EEGQVCVVYCEELKCWCRAIVKSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQ 117
Query: 875 VKAQAFRCSLYNLIQPVGQN------------PFVWDVKAIQAFNEFIDNAWQKNLELKC 922
+ +A + SLY +PV + WD AIQ F + Q L
Sbjct: 118 LPYRAKKFSLY-CTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCA 176
Query: 923 T------IFALASINEELFNIVDLLTPFQSACH 949
++ +I +E + D L AC+
Sbjct: 177 VEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACY 209
>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
Length = 903
Score = 39.3 bits (90), Expect = 0.041
Identities = 40/147 (27%), Positives = 61/147 (41%), Gaps = 21/147 (14%)
Query: 1032 SPLNPGTLCLAKYTDGNWYRGIVI----EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYD 1087
+P+ +C A DG W+R V+ E ++ +VD+G V D L I S D
Sbjct: 757 TPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRS---D 813
Query: 1088 VLLLPMQAVRCSLSDI-----PDHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIELY 1142
+ LP Q L + D E E + +L A V + P G +I+L+
Sbjct: 814 FVTLPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLW 873
Query: 1143 ---GDNIQISASINKKL---GLLSYKD 1163
GD + + IN+ L GL + D
Sbjct: 874 SVVGDEVVL---INRSLVERGLAQWVD 897
Score = 38.5 bits (88), Expect = 0.070
Identities = 16/54 (29%), Positives = 30/54 (55%)
Query: 317 CASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMP 370
CA+ G DG W+RA ++ ++ ++ +VDYG + V LR + ++ +P
Sbjct: 765 CAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLP 818
Score = 33.5 bits (75), Expect = 2.2
Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 771 GSTVEVRVSYVENPGYFWCQLTRN--IQGLKTLMSDIQYYCKN-----TAAPHQRNTLAC 823
G TVEV V N G+ + Q + L++L + Y C + T T+ C
Sbjct: 707 GITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQM-YLCYSQPGIPTLPTPVEITVIC 765
Query: 824 LAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQ 878
A W +++ + V + +VDYG + V V + I +F+ + Q
Sbjct: 766 AAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQ 820
>gi|110735439 Werner syndrome protein [Homo sapiens]
Length = 1432
Score = 38.9 bits (89), Expect = 0.053
Identities = 67/261 (25%), Positives = 107/261 (40%), Gaps = 47/261 (18%)
Query: 1664 EITILEIRRDVCDIPLAIVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSEIKQTLGSY 1723
EI + ++ + + I ++DL K+E + I EN+ S + +GS
Sbjct: 244 EILLSDMNKQLTSISEEVMDLAKHLPHAFSKLENPRRVSILLKDISENLYSLRRMIIGST 303
Query: 1724 NLDVGLKKLSN-----------KAVQNK--------IYMEQQT-----DELAEITEKDV- 1758
N++ L+ +N VQ K I++E +T D LA+ +DV
Sbjct: 304 NIETELRPSNNLNLLSFEDSTTGGVQQKQIREHEVLIHVEDETWDPTLDHLAKHDGEDVL 363
Query: 1759 -NIIGTKPSNFRDPKTDN-ICEGFENPCKDKIDTEELEGEL------ECHLVDKAEFDDK 1810
N + K F D DN + E E C +D E E ++ E +L D A +
Sbjct: 364 GNKVERKEDGFEDGVEDNKLKENMERACLMSLDITEHELQILEQQSQEEYLSDIAYKSTE 423
Query: 1811 YLITGFN-TLLPHANETKEILELNSLEVPLSPDD---------ESKEFLELE---SIELQ 1857
+L N + E+ E LE+ L+ LSP+D ES E LE+E S+E
Sbjct: 424 HLSPNDNENDTSYVIESDEDLEMEMLK-HLSPNDNENDTSYVIESDEDLEMEMLKSLENL 482
Query: 1858 NSLVVDEEKGELSPVPPNVPL 1878
NS V+ + + N+ L
Sbjct: 483 NSGTVEPTHSKCLKMERNLGL 503
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 38.9 bits (89), Expect = 0.053
Identities = 46/220 (20%), Positives = 96/220 (43%), Gaps = 21/220 (9%)
Query: 1120 LDKSLKALVVAKDPDGTLIIELYGDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTET 1179
+ K+++ L + K + T +E D I+ INKKL I ++E E L
Sbjct: 290 MQKTIQVLQIEK-VESTKKMEQLEDKIK---DINKKLSSAENDRDILRREQEQLNVEKRQ 345
Query: 1180 LEEKNENMKLPCTEYLSKSVGYKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLVTQY 1239
+ E+ EN+KL C++ L+ S Q ++ ++ ++L V +
Sbjct: 346 IMEECENLKLECSK---------------LQPSAVKQSDTMTEKERILAQSASVEEVFRL 390
Query: 1240 QDSVGNKNSQVFPLTTEKKEEISAETPLK-TARVEATLSERKIGDSCDKDLPLKFCEFPQ 1298
Q ++ + +++ L++ ++ AE LK R+E E+ + ++L + +
Sbjct: 391 QQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNN 450
Query: 1299 KTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEISH-LSER 1337
+ + T +S ++L D + L E E++ +SE+
Sbjct: 451 EYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEK 490
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 37.7 bits (86), Expect = 0.12
Identities = 80/410 (19%), Positives = 164/410 (40%), Gaps = 67/410 (16%)
Query: 1660 EDVLEITILEIRRDVCDIPLAIVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSEIKQT 1719
+++ EI + E ++V ++ I+ + + +N+++ + G+K + ++KQ
Sbjct: 1059 QEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK 1118
Query: 1720 LGSYN--------LDVGLKKLS---NKAVQNKIYMEQQTDELAEITEKDVNIIGTKPSNF 1768
N L L+KL NK+++ ++++Q EL + E+D +
Sbjct: 1119 SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVS------ 1172
Query: 1769 RDPKTDNICEGFENPCKDKIDTEELEGELECHLVDKAEFDDKYLITGFNTLLPHANETKE 1828
E K K EE + H +DK L E K+
Sbjct: 1173 ------------ELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSL------------EFKK 1208
Query: 1829 ILELNSLEVPLSPDDESKEFLELESIELQNSLVVDEEKGELSPVPPNVPLSQECVTKGAM 1888
+ E ++++ + +++ LE ++ EL ++ + + + + Q TK
Sbjct: 1209 LSEELAIQLDIC-CKKTEALLEAKTNEL-----INISSSKTNAILSRISHCQHRTTKVKE 1262
Query: 1889 ELFTLQLPLSCEAEKQPELELPTAQLPLDDKMDPLSLGVSQKAQESMCTEDMRKS--SCV 1946
L +S ELE Q L ++ + L++ Q + E+ KS + +
Sbjct: 1263 ALLIKTCTVS-------ELEAQLRQ--LTEEQNTLNISFQQATHQLEEKENQIKSMKADI 1313
Query: 1947 ESFDDQRRMSLHLHGADCDPKTQNEMNICEEEFVEYKNRDAISALMPLFSEEESSDGSKH 2006
ES ++ G ++ E I + + +N +A++ LM +E+ + S
Sbjct: 1314 ESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVT-LMKEELKEKKVEISSL 1372
Query: 2007 NNGLPDHISAQLQNTYTLKAFTVGSKCVVWSSLRNTW--SKCEILETAEE 2054
+ L D ++ QLQN+ +L K SSLR + KCE+L+ ++
Sbjct: 1373 SKQLTD-LNVQLQNSISL-----SEKEAAISSLRKQYDEEKCELLDQVQD 1416
Score = 32.0 bits (71), Expect = 6.5
Identities = 47/204 (23%), Positives = 93/204 (45%), Gaps = 14/204 (6%)
Query: 1682 VDLKSKGKSINEKMEKYSKT---GIKSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQ 1738
++L K K N KM + ++ GI A+ +++ K+ + S +V ++L++
Sbjct: 990 LELSQKEKQFNAKMLEMAQANSAGISDAV--SRLETNQKEQIESLT-EVHRRELNDVISI 1046
Query: 1739 NKIYMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDK-IDTEELEGEL 1797
+ + QQ +EL EI E + K + K + G E +K I + EG
Sbjct: 1047 WEKKLNQQAEELQEIHEIQLQ---EKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVK 1103
Query: 1798 ECHLVDKAEFDDKYLITGFNTLLPHANETKEILELNSLEVPLSPDDESKEFLELESIELQ 1857
+ +++ + K N+L +ETK L LEV L+ + FL+ + +EL+
Sbjct: 1104 QDTTLNELQEQLKQKSAHVNSLAQ--DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELK 1161
Query: 1858 NSLVVDEEKGELSPVPPNVPLSQE 1881
++ +E+K ++S + + + E
Sbjct: 1162 --MLAEEDKRKVSELTSKLKTTDE 1183
>gi|197313728 pleckstrin homology-like domain, family B, member 2
isoform b [Homo sapiens]
Length = 1237
Score = 37.4 bits (85), Expect = 0.16
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 14/131 (10%)
Query: 1744 EQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELECHLVD 1803
EQ++ ELA + E + I+ + K N D++D E ++EC L+D
Sbjct: 608 EQRSQELAAMEETRIVILNNLEELKQKIKDIN----------DQMDESFRELDMECALLD 657
Query: 1804 KAEFDDKYLITGFNTLLPHANETKEILELNSLEVPLSPDD----ESKEFLELESIELQNS 1859
+ + + +L H N LE N + D ESK F +LE +L++
Sbjct: 658 GEQKSETTELMKEKEILDHLNRKIAELEKNIVGEKTKDADLLDVESKHFEDLEFQQLEHE 717
Query: 1860 LVVDEEKGELS 1870
+DEEK L+
Sbjct: 718 SRLDEEKENLT 728
>gi|21955172 pleckstrin homology-like domain, family B, member 2
isoform c [Homo sapiens]
Length = 1210
Score = 37.4 bits (85), Expect = 0.16
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 14/131 (10%)
Query: 1744 EQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELECHLVD 1803
EQ++ ELA + E + I+ + K N D++D E ++EC L+D
Sbjct: 581 EQRSQELAAMEETRIVILNNLEELKQKIKDIN----------DQMDESFRELDMECALLD 630
Query: 1804 KAEFDDKYLITGFNTLLPHANETKEILELNSLEVPLSPDD----ESKEFLELESIELQNS 1859
+ + + +L H N LE N + D ESK F +LE +L++
Sbjct: 631 GEQKSETTELMKEKEILDHLNRKIAELEKNIVGEKTKDADLLDVESKHFEDLEFQQLEHE 690
Query: 1860 LVVDEEKGELS 1870
+DEEK L+
Sbjct: 691 SRLDEEKENLT 701
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 35.4 bits (80), Expect = 0.59
Identities = 27/124 (21%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 1656 EIITEDVLEITILEIRRDVCDIPLAIVDLKSKGKSINEKMEKYSKTGIKSALPYENIDSE 1715
E++T+ E + E R+V D+ D+K +++ +++++ + T +NI +
Sbjct: 1064 EMVTDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNT 1123
Query: 1716 IKQTLGSYNLDVGLKKLSNKAVQNKIYMEQQTDELAEITEKDV--------NIIGTKPSN 1767
I++T N A Q + ++E T+ L EI +++ N+ T+P +
Sbjct: 1124 IEET-------------GNLAEQARAHVE-NTERLIEIASRELEKAKVAAANVSVTQPES 1169
Query: 1768 FRDP 1771
DP
Sbjct: 1170 TGDP 1173
>gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo
sapiens]
Length = 1977
Score = 35.4 bits (80), Expect = 0.59
Identities = 53/231 (22%), Positives = 89/231 (38%), Gaps = 27/231 (11%)
Query: 1742 YMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFEN--PCKDKIDTEELEGELEC 1799
+ EQ+ E A + V I+ K + P+ D CE E C D E++ E+E
Sbjct: 745 HKEQEAWEEATSEDSSVVIVDVKEPS---PRVDVSCEPLEGVEKCSDSQSWEDIAPEIEP 801
Query: 1800 HLVDKAEFDDKYLITGFNTLLPHANETKEILELNSL-EVPL-SPDDESKEFLELESIELQ 1857
++ + ++ + L ET+ + + +S +PL DD + EL+ + Q
Sbjct: 802 CAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQ 861
Query: 1858 ----NSLVVDEEKGELSPVP----------PNVPLSQECVTKGAMELFTLQLPLSCEAEK 1903
NSL D + + P+ SQ + F LP E +
Sbjct: 862 EKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPK--EGDI 919
Query: 1904 QPELELPT----AQLPLDDKMDPLSLGVSQKAQESMCTEDMRKSSCVESFD 1950
P L T L L+ K +G+S + ++ T D+ S VE+ D
Sbjct: 920 IPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHD 970
>gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo
sapiens]
Length = 1975
Score = 35.4 bits (80), Expect = 0.59
Identities = 53/231 (22%), Positives = 89/231 (38%), Gaps = 27/231 (11%)
Query: 1742 YMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFEN--PCKDKIDTEELEGELEC 1799
+ EQ+ E A + V I+ K + P+ D CE E C D E++ E+E
Sbjct: 745 HKEQEAWEEATSEDSSVVIVDVKEPS---PRVDVSCEPLEGVEKCSDSQSWEDIAPEIEP 801
Query: 1800 HLVDKAEFDDKYLITGFNTLLPHANETKEILELNSL-EVPL-SPDDESKEFLELESIELQ 1857
++ + ++ + L ET+ + + +S +PL DD + EL+ + Q
Sbjct: 802 CAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQ 861
Query: 1858 ----NSLVVDEEKGELSPVP----------PNVPLSQECVTKGAMELFTLQLPLSCEAEK 1903
NSL D + + P+ SQ + F LP E +
Sbjct: 862 EKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPK--EGDI 919
Query: 1904 QPELELPT----AQLPLDDKMDPLSLGVSQKAQESMCTEDMRKSSCVESFD 1950
P L T L L+ K +G+S + ++ T D+ S VE+ D
Sbjct: 920 IPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHD 970
>gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo
sapiens]
Length = 1972
Score = 35.4 bits (80), Expect = 0.59
Identities = 53/231 (22%), Positives = 89/231 (38%), Gaps = 27/231 (11%)
Query: 1742 YMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFEN--PCKDKIDTEELEGELEC 1799
+ EQ+ E A + V I+ K + P+ D CE E C D E++ E+E
Sbjct: 740 HKEQEAWEEATSEDSSVVIVDVKEPS---PRVDVSCEPLEGVEKCSDSQSWEDIAPEIEP 796
Query: 1800 HLVDKAEFDDKYLITGFNTLLPHANETKEILELNSL-EVPL-SPDDESKEFLELESIELQ 1857
++ + ++ + L ET+ + + +S +PL DD + EL+ + Q
Sbjct: 797 CAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQ 856
Query: 1858 ----NSLVVDEEKGELSPVP----------PNVPLSQECVTKGAMELFTLQLPLSCEAEK 1903
NSL D + + P+ SQ + F LP E +
Sbjct: 857 EKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPK--EGDI 914
Query: 1904 QPELELPT----AQLPLDDKMDPLSLGVSQKAQESMCTEDMRKSSCVESFD 1950
P L T L L+ K +G+S + ++ T D+ S VE+ D
Sbjct: 915 IPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHD 965
>gi|4506869 secreted and transmembrane 1 precursor [Homo sapiens]
Length = 248
Score = 35.4 bits (80), Expect = 0.59
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 32 LWGLVGERRGEY---LRLSREIQEAAATRGQWALGSASASPGELCLVQVGLLWHRCRVVS 88
+W LVG +R L +S ++A G W + + + L + V W+RCR S
Sbjct: 116 MWHLVGHQRNNRQVTLEVSGAEPQSAPDTGFWPVPAVVTAVFILLVALVMFAWYRCR-CS 174
Query: 89 RQAQESRVFLLDEGRTITA 107
+Q +E + FLL+ + A
Sbjct: 175 QQRREKKFFLLEPQMKVAA 193
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 35.0 bits (79), Expect = 0.77
Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 13/139 (9%)
Query: 1200 GYKLPNKEILEESYKPQINSSYKELKLLQSLTKTNLVTQYQDSVGNKNSQVFPLTTEKKE 1259
G K+ + E E ++ ++N++ +E+ + L++T+L TQ D + ++ LT +K+
Sbjct: 131 GEKIRDLEFCLEEHREKVNAT-EEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKD 189
Query: 1260 EISAETPLKTARVEATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSD 1319
+ E + E + E DL LK E + + K S ++L+
Sbjct: 190 RLDYEDKFRDT--EGLIQEIN-------DLRLKVSEMDSERLQYEKKLK---STKDELAS 237
Query: 1320 FYVQLIEDEAEISHLSERL 1338
QL E E+E+ L E+L
Sbjct: 238 LKEQLEEKESEVKRLQEKL 256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,921,136
Number of Sequences: 37866
Number of extensions: 3718136
Number of successful extensions: 11749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 11253
Number of HSP's gapped (non-prelim): 296
length of query: 2096
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1978
effective length of database: 13,779,330
effective search space: 27255514740
effective search space used: 27255514740
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.