BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|57863257 T-complex protein 1 isoform a [Homo sapiens] (556 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 1068 0.0 gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 773 0.0 gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 302 6e-82 gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 294 2e-79 gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 286 3e-77 gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 280 2e-75 gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 276 3e-74 gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 267 2e-71 gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 245 7e-65 gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 242 6e-64 gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 242 6e-64 gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 239 4e-63 gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 181 2e-45 gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 173 4e-43 gi|7657253 T-complex protein 1 [Homo sapiens] 122 7e-28 gi|41399285 chaperonin [Homo sapiens] 58 2e-08 gi|31542947 chaperonin [Homo sapiens] 58 2e-08 gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 49 9e-06 gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] 40 0.007 gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] 40 0.007 gi|31543157 glycine-N-acyltransferase-like 1 [Homo sapiens] 33 0.90 gi|7706322 homeobox prox 1 [Homo sapiens] 32 1.5 gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens] 29 9.9 gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 29 9.9 gi|46048234 nucleolar protein 8 [Homo sapiens] 29 9.9 >gi|57863257 T-complex protein 1 isoform a [Homo sapiens] Length = 556 Score = 1068 bits (2763), Expect = 0.0 Identities = 556/556 (100%), Positives = 556/556 (100%) Query: 1 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT 60 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT Sbjct: 1 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT 60 Query: 61 ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG 120 ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG Sbjct: 61 ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG 120 Query: 121 YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK 180 YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK Sbjct: 121 YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK 180 Query: 181 YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS 240 YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS Sbjct: 181 YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS 240 Query: 241 LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF 300 LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF Sbjct: 241 LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF 300 Query: 301 VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE 360 VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE Sbjct: 301 VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE 360 Query: 361 LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS 420 LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS Sbjct: 361 LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS 420 Query: 421 IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER 480 IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER Sbjct: 421 IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER 480 Query: 481 KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540 KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD Sbjct: 481 KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540 Query: 541 KHGSYEDAVHSGALND 556 KHGSYEDAVHSGALND Sbjct: 541 KHGSYEDAVHSGALND 556 >gi|57863259 T-complex protein 1 isoform b [Homo sapiens] Length = 401 Score = 773 bits (1996), Expect = 0.0 Identities = 401/401 (100%), Positives = 401/401 (100%) Query: 156 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA 215 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA 60 Query: 216 LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERI 275 LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERI Sbjct: 61 LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERI 120 Query: 276 QKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 335 QKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE Sbjct: 121 QKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 180 Query: 336 GEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDA 395 GEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDA Sbjct: 181 GEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDA 240 Query: 396 LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 455 LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN Sbjct: 241 LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 300 Query: 456 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK 515 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK Sbjct: 301 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK 360 Query: 516 FATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND 556 FATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND Sbjct: 361 FATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND 401 >gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo sapiens] Length = 543 Score = 302 bits (773), Expect = 6e-82 Identities = 192/537 (35%), Positives = 294/537 (54%), Gaps = 28/537 (5%) Query: 10 DRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH 69 D S G N+ A IA V+++LGP G+DK++VD G TI+NDGATILKLL+V H Sbjct: 14 DSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVH 73 Query: 70 PAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAV 129 PAAK L ++A QD EVGDGTTSV ++AAE LK V++ +HP +I +R A + AV Sbjct: 74 PAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAV 133 Query: 130 RYINENLIV--NTDEL-GRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRG 186 I E + D++ R L A T++SSK+I FFA MVVDAV+ + Sbjct: 134 NKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMML------- 186 Query: 187 QPRYPVNSVNILKAHGRSQMESMLISGYALN---CVVGSQGMPKRIVNAKIACLDFSLQK 243 + + I K G + +S L++G A G + PK+ N KIA L+ L+ Sbjct: 187 DDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL 246 Query: 244 TKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEA 303 K ++ + E I E +I ++++KI +GA V+L+ I D+ +YF + Sbjct: 247 KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADR 306 Query: 304 GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELIL 363 RV + DLKR A G +I +++ A +LG+ + + +I + Sbjct: 307 DMFCAGRVPEEDLKRTMMACGGSIQTSV------NALSADVLGRCQVFEETQIGGERYNF 360 Query: 364 IKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL 423 + + ILRG + +E ERSLHDA+ +V+R +++ SVV GGGA+E LS YL Sbjct: 361 FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL 420 Query: 424 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL 483 +Y+ ++ ++QL I +A++L +IP L NA D+T+++ KLRA H + Sbjct: 421 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT------- 473 Query: 484 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540 W G+D++N DN +A V+EP +V++ +L A+EAA I+ +D+ IK +P S D Sbjct: 474 -WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTVD 528 >gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] Length = 535 Score = 294 bits (752), Expect = 2e-79 Identities = 193/547 (35%), Positives = 305/547 (55%), Gaps = 30/547 (5%) Query: 4 PLSVF---GDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVT--ITNDG 58 P+++F D ET R + + A +I ++VKS+LGP G+DK+L+ D + +TNDG Sbjct: 8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67 Query: 59 ATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVI 118 ATILK + V++PAAKVL +++ +QD EVGDGTTSV ++AAELL+ A+ L+ +KIHP ++I Sbjct: 68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127 Query: 119 SGYRLACKEAVRYINENLIVN-TDELG-RDCLINAAKTSMSSKIIGINGDFFANMVVDAV 176 +G+R A K A + + + + +DE+ R L+N A T++SSK++ + D F + V+AV Sbjct: 128 AGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAV 187 Query: 177 LAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIAC 236 L +K + + +++I+K G S +S L G+ L+ +G PKRI NAKI Sbjct: 188 LRLKGSG-------NLEAIHIIKKLGGSLADSYLDEGFLLDKKIG-VNQPKRIENAKILI 239 Query: 237 LDFSLQKTKMKL-GVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDM 295 + + K+K+ G +V + K+ +I E + KE++++IL G N + I + Sbjct: 240 ANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNY 299 Query: 296 CLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQER 355 + F AG MA+ ++R+A +G I ST + E LG + + + Sbjct: 300 PEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTF------DHPELVKLGSCKLIEEVM 353 Query: 356 ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAV 415 I +D+LI + +I+LRGA + DE ERSLHDALCV+ + ++ V GGG Sbjct: 354 IGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCS 413 Query: 416 EAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQ 475 E ++ + A +E +A+ +A++L ++P +A NA DS DLVA+LRA H+E Sbjct: 414 EMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN 473 Query: 476 VNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHP 535 GLD+ G D G+ E VK + L A EAA ILR+D++IK P Sbjct: 474 TT--------AGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAP 525 Query: 536 ESKDDKH 542 + H Sbjct: 526 RKRVPDH 532 >gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo sapiens] Length = 545 Score = 286 bits (733), Expect = 3e-77 Identities = 181/541 (33%), Positives = 297/541 (54%), Gaps = 17/541 (3%) Query: 11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70 R +G ++S N+ AA +IA+I+++ LGP + KML+D +G + +TNDG IL+ ++V+HP Sbjct: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75 Query: 71 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130 AAK + E++ QD+EVGDGTTSV+I+A E+L A+ ++Q++HPT VIS YR A + + Sbjct: 76 AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 135 Query: 131 YINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRY 190 + + + + D D ++N +S+++K I N+ +DAV +++ + G+ Sbjct: 136 TL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEI 193 Query: 191 PVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLG 249 + + K G +S ++ G +N V M + I N +I LD SL+ K + Sbjct: 194 DIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQ 253 Query: 250 VQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVR 309 + IT E +I Q E + ++ + I+ +V++T GI D+ Y + A A+R Sbjct: 254 TDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIR 313 Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369 RV K D RIA+A GA I+S L ++ A L + ++I D+ I + K Sbjct: 314 RVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTFITDCKD 368 Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429 + +I+LRGA+ + E+ER+L DA+ V + VL +VPGGGA E A++ L + + Sbjct: 369 PKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 428 Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489 M EQ A++L VIP TL N + L+ LRA H + +N + G++ Sbjct: 429 MTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENCETWGVN 481 Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--KHGSYED 547 G D K+ G++EP VK+++ K A E A+ +LRIDD++ H + DD + G D Sbjct: 482 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 541 Query: 548 A 548 A Sbjct: 542 A 542 >gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo sapiens] Length = 544 Score = 280 bits (717), Expect = 2e-75 Identities = 180/541 (33%), Positives = 296/541 (54%), Gaps = 18/541 (3%) Query: 11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70 R +G ++S N+ AA +IA+I+++ LGP + KML+D +G + +TNDG IL+ ++V+HP Sbjct: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75 Query: 71 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130 AAK + E++ QD+EVGDGTTSV+I+ E+L A+ ++Q++HPT VIS YR A + + Sbjct: 76 AAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 134 Query: 131 YINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRY 190 + + + + D D ++N +S+++K I N+ +DAV +++ + G+ Sbjct: 135 TL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEI 192 Query: 191 PVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLG 249 + + K G +S ++ G +N V M + I N +I LD SL+ K + Sbjct: 193 DIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQ 252 Query: 250 VQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVR 309 + IT E +I Q E + ++ + I+ +V++T GI D+ Y + A A+R Sbjct: 253 TDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIR 312 Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369 RV K D RIA+A GA I+S L ++ A L + ++I D+ I + K Sbjct: 313 RVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTFITDCKD 367 Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429 + +I+LRGA+ + E+ER+L DA+ V + VL +VPGGGA E A++ L + + Sbjct: 368 PKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 427 Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489 M EQ A++L VIP TL N + L+ LRA H + +N + G++ Sbjct: 428 MTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENCETWGVN 480 Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--KHGSYED 547 G D K+ G++EP VK+++ K A E A+ +LRIDD++ H + DD + G D Sbjct: 481 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 540 Query: 548 A 548 A Sbjct: 541 A 541 >gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo sapiens] Length = 539 Score = 276 bits (707), Expect = 3e-74 Identities = 173/532 (32%), Positives = 296/532 (55%), Gaps = 27/532 (5%) Query: 8 FGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEV 67 + DR IR N+ AA ++A+ +++SLGP G+DKM+ D GDVTITNDGATILK ++V Sbjct: 24 YQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQV 83 Query: 68 EHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKE 127 HPAA++L EL+ QD E GDGTTSVVIIA LL + +L+++ IHPT + ++ A ++ Sbjct: 84 LHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEK 143 Query: 128 AVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQ 187 + + + + + R+ L+N+A TS++SK++ + M V+AV+ K D Sbjct: 144 GIEILTD-MSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVM--KVIDPATA 200 Query: 188 PRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMK 247 + + I+K G + + L+ G L V + G+ R+ AKI + F L K Sbjct: 201 TSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTD 259 Query: 248 LGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGI-----DDMCLKYFVE 302 + Q+V++D ++D++ + E +++I TG NV+L I D+ L + + Sbjct: 260 MDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNK 319 Query: 303 AGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELI 362 M ++ + + D++ I K G ++ + + F A MLG A E+ +E + Sbjct: 320 MKIMVIKDIEREDIEFICKTIGTKPVAHI------DQFTADMLGSA-ELAEEVNLNGSGK 372 Query: 363 LIKNTKART---SASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAAL 419 L+K T + + +I++RG+N + +E ERS+HDALCV++ +++ ++++ GGGA E L Sbjct: 373 LLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIEL 432 Query: 420 SIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPE 479 ++ L Y+ ++ E + FA ++ VIP+TLA NA + V +LR H + + Sbjct: 433 ALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE---- 488 Query: 480 RKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLI 531 K G+++ G + + V +P +V V +L ATE +IL+IDD++ Sbjct: 489 ----KTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVV 536 >gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo sapiens] Length = 541 Score = 267 bits (683), Expect = 2e-71 Identities = 171/524 (32%), Positives = 290/524 (55%), Gaps = 26/524 (4%) Query: 15 ETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKV 74 E ++S ++MAA ++AN +++SLGP GLDKM+VD GDVT+TNDGATIL +++V+H AK+ Sbjct: 32 EALKS-HIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKL 90 Query: 75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRY--- 131 + EL+ QD E+GDGTT VV++A LL+ A++L+ + IHP + GY A + A+ + Sbjct: 91 MVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDK 150 Query: 132 INENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYP 191 I+++++V+ + + LI AKT++ SK++ A + V+AVL + + R Sbjct: 151 ISDSVLVDIKD--TEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDV---- 204 Query: 192 VNSVNILKAHGR---SQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL 248 ++K G+ ++ LI G ++ MPK++ +AKIA L + K K Sbjct: 205 --DFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKT 262 Query: 249 GVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAV 308 ++ +T E +++ E + +E IQ+I TGAN+ + G DD ++ AV Sbjct: 263 KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAV 322 Query: 309 RRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTK 368 R V +++ IA A+G I+ + L E+ A ++ + + D++++I+ K Sbjct: 323 RWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLV----QEISFGTTKDKMLVIEQCK 378 Query: 369 ARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYAT 428 + +I +RG N + +E +RSLHDALCV++ ++ VV GGGA E + ++ + A Sbjct: 379 NSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEAD 438 Query: 429 SMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGL 488 + EQ A+ FA +L VIP L+ N+ + + ++RA ++NP +G+ Sbjct: 439 KCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRA-RQVKEMNPA------LGI 491 Query: 489 DLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532 D + D KQ V E I K + + AT+ IL+IDD+ K Sbjct: 492 DCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRK 535 >gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo sapiens] Length = 548 Score = 245 bits (626), Expect = 7e-65 Identities = 163/521 (31%), Positives = 277/521 (53%), Gaps = 27/521 (5%) Query: 20 QNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELA 79 +N+ A +A +++ GP G++KM+++ + + +TND ATIL+ LEV+HPAAK++ + Sbjct: 31 RNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMAS 90 Query: 80 DLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVN 139 +Q++EVGDGT V++ A LL+ A+EL++ + + VI GY +AC++A I NL+ Sbjct: 91 HMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKA-HEILPNLVCC 149 Query: 140 TDELGRDC--LINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNI 197 + + RD + + +TS+ SK G N F A ++ A ++I + V+++ + Sbjct: 150 SAKNLRDIDEVSSLLRTSIMSKQYG-NEVFLAKLIAQACVSI----FPDSGHFNVDNIRV 204 Query: 198 LKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDP 257 K G S ++ G ++G + +AKIA + V+I Sbjct: 205 CKILGSGISSSSVLHGMVFK--KETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTA 262 Query: 258 EKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLK 317 E+L + E ++ +++ I TGANV++T G + DM L Y + M VR K DL+ Sbjct: 263 EELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLR 322 Query: 318 RIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSAS-II 376 R+ K GAT L L EE +G + V + D ++++ K+ K + S I+ Sbjct: 323 RLCKTVGATALPRLTPPVLEE------MGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIV 376 Query: 377 LRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQL 436 LRG+ D + D++ER++ D + K + K +VPGGGA E L+ + +Y + EQ Sbjct: 377 LRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQY 436 Query: 437 AIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKP- 495 AI +FA + IP LA N+ + ++++KL A H E N +GLD+ P Sbjct: 437 AIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKN--------VGLDIEAEVPA 488 Query: 496 -RDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHP 535 +D +AG+ + + K ++K AT AA+T+LR+D +I P Sbjct: 489 VKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKP 529 >gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] Length = 530 Score = 242 bits (618), Expect = 6e-64 Identities = 150/523 (28%), Positives = 277/523 (52%), Gaps = 33/523 (6%) Query: 21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80 N+ AA + ++++++LGP G KMLV GD+ +T DG +L ++++HP A ++ ++A Sbjct: 23 NICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVAT 82 Query: 81 LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140 QD GDGTTS V+I ELLK AD + + +HP + G+ A +A+ + E + T Sbjct: 83 AQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEE--VKVT 140 Query: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNIL 198 E+ R L++ A+TS+ +K+ D +VVD+VLA++ +P YP++ V I+ Sbjct: 141 KEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR------RPGYPIDLFMVEIM 194 Query: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258 + + ++ LI G L+ M KR+ +A I + SL+ K ++ E Sbjct: 195 EMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAE 254 Query: 259 KLDQIRQRESDITKERIQKIL---------ATGANVILTTGGIDDMCLKYFVEAGAMAVR 309 + +++ + E ++R+QKI+ + V++ GID L + G +A+R Sbjct: 255 EKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALR 314 Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369 R +R+++R++ A G +++ +L + LG A V + + +++ I+ Sbjct: 315 RAKRRNMERLSLACGGMAVNSFEDLTVD------CLGHAGLVYEYTLGEEKFTFIEECVN 368 Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429 S +++++G N +++ ++ D L +K +E +VPG GA+E A++ L Y S Sbjct: 369 PCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNS 428 Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489 + R +L + FA +LL+IP LA NA D + + K++A H E++ + +G+D Sbjct: 429 IKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESK--------QLVGVD 480 Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532 L+ G+P AGV++ VK + L T A IL +D++++ Sbjct: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 523 >gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo sapiens] Length = 531 Score = 242 bits (618), Expect = 6e-64 Identities = 150/521 (28%), Positives = 279/521 (53%), Gaps = 29/521 (5%) Query: 21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80 N+ AA + ++++++LGP G KMLV GD+ +T DG +L ++++HP A ++ ++A Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82 Query: 81 LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140 QD GDGTTS V+I ELLK AD + + +HP + G+ A ++A++++ E + + Sbjct: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEE--VKVS 140 Query: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKA 200 E+ R+ LI+ A+TS+ +K+ D VVD++LAIK D +P + + I++ Sbjct: 141 REMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EP-IDLFMIEIMEM 196 Query: 201 HGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKL 260 +S+ ++ LI G L+ M KR+ +A I + SL+ K ++ E+ Sbjct: 197 KHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEER 256 Query: 261 DQIRQRESDITKERIQKIL---------ATGANVILTTGGIDDMCLKYFVEAGAMAVRRV 311 +++ + E ++R++KI+ + V++ GID L + G +A+RR Sbjct: 257 EKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRA 316 Query: 312 LKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKART 371 +R+++R+ A G L++ +L + LG A V + + +++ I+ Sbjct: 317 KRRNMERLTLACGGVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNNPR 370 Query: 372 SASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMG 431 S +++++G N +++ ++ D L VK ++ VVPG GAVE A++ L + S+ Sbjct: 371 SVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVK 430 Query: 432 SREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLS 491 R QL + FA +LL+IP LA N+ D + + K++A H+E+ + +G+DL+ Sbjct: 431 GRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVDLN 482 Query: 492 NGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532 G+P + GV++ VK + L T A IL +D++++ Sbjct: 483 TGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 523 >gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo sapiens] Length = 507 Score = 239 bits (611), Expect = 4e-63 Identities = 158/487 (32%), Positives = 259/487 (53%), Gaps = 17/487 (3%) Query: 65 LEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLA 124 ++V+HPAAK + E++ QD+EVGDGTTSV+I+A E+L A+ ++Q++HPT VIS YR A Sbjct: 32 IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91 Query: 125 CKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDI 184 + + + + + + D D ++N +S+++K I N+ +DAV +++ + Sbjct: 92 LDDMISTL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE- 149 Query: 185 RGQPRYPVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQK 243 G+ + + K G +S ++ G +N V M + I N +I LD SL+ Sbjct: 150 NGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY 209 Query: 244 TKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEA 303 K + + IT E +I Q E + ++ + I+ +V++T GI D+ Y + A Sbjct: 210 KKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRA 269 Query: 304 GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELIL 363 A+RRV K D RIA+A GA I+S L ++ A L + ++I D+ Sbjct: 270 NITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTF 324 Query: 364 IKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL 423 I + K + +I+LRGA+ + E+ER+L DA+ V + VL +VPGGGA E A++ L Sbjct: 325 ITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHAL 384 Query: 424 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL 483 + +M EQ A++L VIP TL N + L+ LRA H + +N Sbjct: 385 TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENC 437 Query: 484 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--K 541 + G++ G D K+ G++EP VK+++ K A E A+ +LRIDD++ H + DD + Sbjct: 438 ETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSR 497 Query: 542 HGSYEDA 548 G DA Sbjct: 498 QGGAPDA 504 >gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo sapiens] Length = 486 Score = 181 bits (459), Expect = 2e-45 Identities = 132/523 (25%), Positives = 250/523 (47%), Gaps = 78/523 (14%) Query: 21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80 N+ AA + ++++++LGP G KMLV GD+ +T DG +L Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLH----------------- 65 Query: 81 LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140 E+G +HP + G+ A ++A++++ E + + Sbjct: 66 ----EMG------------------------LHPRIITEGFEAAKEKALQFLEEVKV--S 95 Query: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNIL 198 E+ R+ LI+ A+TS+ +K+ D VVD++LAIK D P++ + I+ Sbjct: 96 REMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD------EPIDLFMIEIM 149 Query: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258 + +S+ ++ LI G L+ M KR+ +A I + SL+ K ++ E Sbjct: 150 EMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAE 209 Query: 259 KLDQIRQRESDITKERIQKILATGANV---------ILTTGGIDDMCLKYFVEAGAMAVR 309 + +++ + E ++R++KI+ V ++ GID L + G +A+R Sbjct: 210 EREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALR 269 Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369 R +R+++R+ A G L++ +L + LG A V + + +++ I+ Sbjct: 270 RAKRRNMERLTLACGGVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNN 323 Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429 S +++++G N +++ ++ D L VK ++ VVPG GAVE A++ L + S Sbjct: 324 PRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPS 383 Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489 + R QL + FA +LL+IP LA N+ D + + K++A H+E+ + +G+D Sbjct: 384 VKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVD 435 Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532 L+ G+P + GV++ VK + L T A IL +D++++ Sbjct: 436 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 478 >gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo sapiens] Length = 339 Score = 173 bits (438), Expect = 4e-43 Identities = 109/338 (32%), Positives = 182/338 (53%), Gaps = 18/338 (5%) Query: 206 MESMLISGYALN---CVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQ 262 M+S L++G A G + PK+ N KIA L+ L+ K ++ + E Sbjct: 2 MDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQA 61 Query: 263 IRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKA 322 I E +I ++++KI +GA V+L+ I D+ +YF + RV + DLKR A Sbjct: 62 IVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMA 121 Query: 323 SGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGAND 382 G +I +++ L + +LG+ + + +I + + + ILRG + Sbjct: 122 CGGSIQTSVNALSAD------VLGRCQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAE 175 Query: 383 FMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFA 442 +E ERSLHDA+ +V+R +++ SVV GGGA+E LS YL +Y+ ++ ++QL I +A Sbjct: 176 QFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYA 235 Query: 443 RSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAG 502 ++L +IP L NA D+T+++ KLRA H + W G+D++N DN +A Sbjct: 236 KALEIIPRQLCDNAGFDATNILNKLRARHAQGGT--------WYGVDINNEDIADNFEAF 287 Query: 503 VFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540 V+EP +V++ +L A+EAA I+ +D+ IK +P S D Sbjct: 288 VWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTVD 324 >gi|7657253 T-complex protein 1 [Homo sapiens] Length = 557 Score = 122 bits (307), Expect = 7e-28 Identities = 113/514 (21%), Positives = 221/514 (42%), Gaps = 31/514 (6%) Query: 21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80 ++ A ++A++++ GP G K LV G+ T IL+ LE+EHPAA +L E Sbjct: 36 SLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAGQ 95 Query: 81 LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140 Q + GDGT VV++ LL+ A++L+K + + Y A E + + I + Sbjct: 96 TQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAIQSL 155 Query: 141 DELGRD--CLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNIL 198 L L + T S + D +V A AIK D +P V + Sbjct: 156 GPLEDPSWALHSVMNTHTLSPM-----DHLTKLVAHACWAIKELDGSFKP----ERVGVC 206 Query: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258 G + +S L+ G A++ + Q M + A++A ++ P Sbjct: 207 ALPGGTLEDSCLLPGLAISGKLCGQ-MATVLSGARVALFACPFGPAHPNAPATARLSSPA 265 Query: 259 KLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKR 318 L Q + + ++++ ++ A G NV + G +D+ L + G + ++ ++ Sbjct: 266 DLAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQARSWMEIIY 325 Query: 319 IAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSA-SIIL 377 +++ +L L G+ + V ++ + D ++ + T A +++L Sbjct: 326 LSEVLDTPLLPRL--------LPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTVVL 377 Query: 378 RGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLA 437 RGA E++++ + ++ + ++PG GA E AL+ L + + + A Sbjct: 378 RGATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPA 437 Query: 438 IAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRD 497 FA +L +P TLA NA +D++A++ H + L +G + + Sbjct: 438 FLAFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNL------LMGVGTE----GIIN 487 Query: 498 NKQAGVFEPTIVKVKSLKFATEAAITILRIDDLI 531 Q GV++ IVK + + E + ++ +D+++ Sbjct: 488 VAQEGVWDTLIVKAQGFRAVAEVVLQLVTVDEIV 521 >gi|41399285 chaperonin [Homo sapiens] Length = 573 Score = 58.2 bits (139), Expect = 2e-08 Identities = 107/567 (18%), Positives = 222/567 (39%), Gaps = 76/567 (13%) Query: 10 DRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH 69 D G R+ + +A+ V ++GP G ++ G +T DG T+ K ++++ Sbjct: 29 DVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKD 88 Query: 70 P----AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLAC 125 AK++ ++A+ ++E GDGTT+ ++A + K E + + +P + G LA Sbjct: 89 KYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAV 148 Query: 126 KEAVRYINE---------------NLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFAN 170 + + + + N D+ + + +A K +I + N Sbjct: 149 DAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN 208 Query: 171 MVVDAVLAIKY----------TDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVV 220 ++ + +K+ +GQ ++ +L S ++S++ AL + Sbjct: 209 DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV---PALE-IA 264 Query: 221 GSQGMPKRIVNAKIACLDFS-LQKTKMKLGVQVV-ITDPEKLDQIRQRESDITKERIQKI 278 + P I+ + S L ++K+G+QVV + P D + + D+ Sbjct: 265 NAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMA------- 317 Query: 279 LATGANVILTTG---GIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 335 +ATG V G ++D+ + G + ++ +D + K G E Sbjct: 318 IATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IVTKDDAMLLKGKGDKAQIEKRIQE 373 Query: 336 GEETFEAAMLGQAEEVVQERIC--DDELILIKNTKARTSASIILRGANDFMCDEMERSLH 393 E + +E + ER+ D + ++K + G +D +E + + Sbjct: 374 IIEQLDVTTSEYEKEKLNERLAKLSDGVAVLK-----------VGGTSDVEVNEKKDRVT 422 Query: 394 DALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLA 453 DAL + +E V+ GG A+ + + T +++ I R+L + T+A Sbjct: 423 DALNATRAAVEEGIVLGGGCALLRCIPAL--DSLTPANEDQKIGIEIIKRTLKIPAMTIA 480 Query: 454 VNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKS 513 NA + + +V K+ +E +G D G + + G+ +PT V + Sbjct: 481 KNAGVEGSLIVEKIMQSSSE------------VGYDAMAGDFVNMVEKGIIDPTKVVRTA 528 Query: 514 LKFATEAAITILRIDDLIKLHPESKDD 540 L A A + + ++ P+ + D Sbjct: 529 LLDAAGVASLLTTAEVVVTEIPKEEKD 555 >gi|31542947 chaperonin [Homo sapiens] Length = 573 Score = 58.2 bits (139), Expect = 2e-08 Identities = 107/567 (18%), Positives = 222/567 (39%), Gaps = 76/567 (13%) Query: 10 DRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH 69 D G R+ + +A+ V ++GP G ++ G +T DG T+ K ++++ Sbjct: 29 DVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKD 88 Query: 70 P----AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLAC 125 AK++ ++A+ ++E GDGTT+ ++A + K E + + +P + G LA Sbjct: 89 KYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAV 148 Query: 126 KEAVRYINE---------------NLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFAN 170 + + + + N D+ + + +A K +I + N Sbjct: 149 DAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN 208 Query: 171 MVVDAVLAIKY----------TDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVV 220 ++ + +K+ +GQ ++ +L S ++S++ AL + Sbjct: 209 DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV---PALE-IA 264 Query: 221 GSQGMPKRIVNAKIACLDFS-LQKTKMKLGVQVV-ITDPEKLDQIRQRESDITKERIQKI 278 + P I+ + S L ++K+G+QVV + P D + + D+ Sbjct: 265 NAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMA------- 317 Query: 279 LATGANVILTTG---GIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 335 +ATG V G ++D+ + G + ++ +D + K G E Sbjct: 318 IATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IVTKDDAMLLKGKGDKAQIEKRIQE 373 Query: 336 GEETFEAAMLGQAEEVVQERIC--DDELILIKNTKARTSASIILRGANDFMCDEMERSLH 393 E + +E + ER+ D + ++K + G +D +E + + Sbjct: 374 IIEQLDVTTSEYEKEKLNERLAKLSDGVAVLK-----------VGGTSDVEVNEKKDRVT 422 Query: 394 DALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLA 453 DAL + +E V+ GG A+ + + T +++ I R+L + T+A Sbjct: 423 DALNATRAAVEEGIVLGGGCALLRCIPAL--DSLTPANEDQKIGIEIIKRTLKIPAMTIA 480 Query: 454 VNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKS 513 NA + + +V K+ +E +G D G + + G+ +PT V + Sbjct: 481 KNAGVEGSLIVEKIMQSSSE------------VGYDAMAGDFVNMVEKGIIDPTKVVRTA 528 Query: 514 LKFATEAAITILRIDDLIKLHPESKDD 540 L A A + + ++ P+ + D Sbjct: 529 LLDAAGVASLLTTAEVVVTEIPKEEKD 555 >gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] Length = 723 Score = 49.3 bits (116), Expect = 9e-06 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Query: 21 NVMAAASIAN----IVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLC 76 +V AA +A IV +GP G + G+V ++ +G +L+ L +EHP A+++ Sbjct: 10 SVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIV 69 Query: 77 ELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHP 114 + K+ GDG + +I LL+ + ++ P Sbjct: 70 DCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDP 107 Score = 31.6 bits (70), Expect = 2.0 Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 21/132 (15%) Query: 408 VVPGGGAVEAALSIYLENYATSMGSREQLAIAE-FARSLLVIPNTLAVNAAQDSTDLVAK 466 V+P GG E L YL NYA E+ ++ A +LL IP L + + Sbjct: 599 VLPVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTY 658 Query: 467 LRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILR 526 +RA H L +P + Q G+ E + K + L + IL Sbjct: 659 IRAVH-----------------ALQTNQPLVSSQTGL-ESVMGKYQLLTSVLQCLTKILT 700 Query: 527 IDDLI--KLHPE 536 ID +I K HP+ Sbjct: 701 IDMVITVKRHPQ 712 >gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] Length = 570 Score = 39.7 bits (91), Expect = 0.007 Identities = 82/430 (19%), Positives = 162/430 (37%), Gaps = 40/430 (9%) Query: 15 ETIRSQNVMAAASIAN-IVKSSLGPVGLDKMLVDDIGD-VTITNDGATILKLLEVEHPAA 72 E + ++ V S+ IV S GP G K L + G V T+ + +L L V HP Sbjct: 15 EPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPIL 74 Query: 73 KVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYI 132 K+L D I+ L++N L + PT+VI + + Y+ Sbjct: 75 KILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYL 131 Query: 133 NENLI---VNTDELGRDCLINAAKTSMSSK----IIGINGDFFANMVVDAVLAIKYTDIR 185 + D L+ ++ ++SK + + + +++ A L + Sbjct: 132 KSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAE 191 Query: 186 GQPRYPVNSVNILKAHGRSQMESMLISGYALNC--VVGSQGMP-KRIVNAKIACLDFSLQ 242 G + I+ G+ ++S ++ G + V + +P K+ K+A +L Sbjct: 192 G--HIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLS 249 Query: 243 KTKMKLGVQVVIT------DPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMC 296 G V+ + LDQ+ + + + +L + Sbjct: 250 GDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQ---------KVIHPS 300 Query: 297 LKYFVEA-GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQER 355 LK F+ +A+ R+ ++ + K +G + +L ++ G ++V + Sbjct: 301 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNS------YGSVKDVCTAK 354 Query: 356 ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAV 415 + +A T S++L ND DE++ + AL V++ L+ + GGG Sbjct: 355 FGSKHFFHLIPNEA-TICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCT 413 Query: 416 EAALSIYLEN 425 E L+ Y+ + Sbjct: 414 ETHLAAYIRH 423 >gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] Length = 570 Score = 39.7 bits (91), Expect = 0.007 Identities = 82/430 (19%), Positives = 162/430 (37%), Gaps = 40/430 (9%) Query: 15 ETIRSQNVMAAASIAN-IVKSSLGPVGLDKMLVDDIGD-VTITNDGATILKLLEVEHPAA 72 E + ++ V S+ IV S GP G K L + G V T+ + +L L V HP Sbjct: 15 EPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPIL 74 Query: 73 KVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYI 132 K+L D I+ L++N L + PT+VI + + Y+ Sbjct: 75 KILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYL 131 Query: 133 NENLI---VNTDELGRDCLINAAKTSMSSK----IIGINGDFFANMVVDAVLAIKYTDIR 185 + D L+ ++ ++SK + + + +++ A L + Sbjct: 132 KSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAE 191 Query: 186 GQPRYPVNSVNILKAHGRSQMESMLISGYALNC--VVGSQGMP-KRIVNAKIACLDFSLQ 242 G + I+ G+ ++S ++ G + V + +P K+ K+A +L Sbjct: 192 G--HIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLS 249 Query: 243 KTKMKLGVQVVIT------DPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMC 296 G V+ + LDQ+ + + + +L + Sbjct: 250 GDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQ---------KVIHPS 300 Query: 297 LKYFVEA-GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQER 355 LK F+ +A+ R+ ++ + K +G + +L ++ G ++V + Sbjct: 301 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNS------YGSVKDVCTAK 354 Query: 356 ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAV 415 + +A T S++L ND DE++ + AL V++ L+ + GGG Sbjct: 355 FGSKHFFHLIPNEA-TICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCT 413 Query: 416 EAALSIYLEN 425 E L+ Y+ + Sbjct: 414 ETHLAAYIRH 423 >gi|31543157 glycine-N-acyltransferase-like 1 [Homo sapiens] Length = 333 Score = 32.7 bits (73), Expect = 0.90 Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 13/148 (8%) Query: 375 IILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSRE 434 +I+R M D+M+ + K +S+ V+ V + ++ S+G E Sbjct: 86 VIIRPQKQEMTDDMDSYTNVYRMFSKEPQKSEEVLKNCEIVNWKQRLQIQGLQESLG--E 143 Query: 435 QLAIAEFARS---------LLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKW 485 + +A F++S LLV + L +NA+ S L + H + + E N K+ Sbjct: 144 GIRVATFSKSVKVEHSRALLLVTEDILKLNASSKSK-LGSWAETGHPDDEFESETPNFKY 202 Query: 486 IGLDLS-NGKPRDNKQAGVFEPTIVKVK 512 LD+S +G DN + G E ++ +K Sbjct: 203 AQLDVSYSGLVNDNWKRGKNERSLHYIK 230 >gi|7706322 homeobox prox 1 [Homo sapiens] Length = 244 Score = 32.0 bits (71), Expect = 1.5 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 12/76 (15%) Query: 25 AASIANIVKSSLGPVGLDKMLVD-DIGDVTITNDGATILKLLEVEHPAAKVLCELADLQD 83 A + AN K L PV LDK ++ D GD + N+ A IL+LL +E EL +LQ Sbjct: 168 AVAKANQTKEGL-PVALDKHILGFDTGDAVL-NEAAQILRLLHIE--------ELRELQT 217 Query: 84 KEVGDGTTSVVIIAAE 99 K + + +V I A+ Sbjct: 218 K-INEAIVAVQAIIAD 232 >gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens] Length = 1453 Score = 29.3 bits (64), Expect = 9.9 Identities = 25/120 (20%), Positives = 51/120 (42%), Gaps = 28/120 (23%) Query: 200 AHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL----------- 248 AH R ++E ++I Y GS G K + + I L+ ++ + + +L Sbjct: 1227 AHERIRLEQLIIDSYEKQQAQGS-GRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLEDL 1285 Query: 249 GVQVVITDPE----------------KLDQIRQRESDITKERIQKILATGANVILTTGGI 292 G++ V D + +++R+ S +TK +++ + ++ TTGGI Sbjct: 1286 GLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGGI 1345 >gi|62241003 cardiomyopathy associated 5 [Homo sapiens] Length = 4069 Score = 29.3 bits (64), Expect = 9.9 Identities = 33/174 (18%), Positives = 75/174 (43%), Gaps = 11/174 (6%) Query: 323 SGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGAND 382 +G ++ T ++ +++ E A + ++++ +CD E ++ K+ S S +L ++ Sbjct: 1470 AGLPVIKTSSSQHSDKS-EEARVEDKQDLLFSTVCDSERLVSSQKKSLMSTSEVLEPEHE 1528 Query: 383 F---MCDEMERSLHDALCVVKRVLESKSVVPGGGAVE-AALSIYLENYATSMGSREQLAI 438 + E+++ + SK ++P G E A+ S LEN A+ + L Sbjct: 1529 LPLSLWGEIKKKETELPSSQNVSPASKHIIPKGKDEETASSSPELENLASGLAPTLLLLS 1588 Query: 439 AEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSN 492 + + + + +T + + D+ E + PE+K+ L+L N Sbjct: 1589 DDKNKPAVEVSSTAQGDFPSEKQDVALA------ELSLEPEKKDKPHQPLELPN 1636 >gi|46048234 nucleolar protein 8 [Homo sapiens] Length = 1167 Score = 29.3 bits (64), Expect = 9.9 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 10/80 (12%) Query: 223 QGMPKRI---VNAKIACLDFS-----LQKTKMKLG-VQVVITDPEKLDQIRQRESDITKE 273 QG P+++ +N +A D L KTK K G +Q+ + L ++ Q E + K Sbjct: 46 QGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKESFLHRLAQ-EREAAKA 104 Query: 274 RIQKILATGANVILTTGGID 293 + ++ AN++ TGG+D Sbjct: 105 KKEESTTGNANLLEKTGGVD 124 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,241,762 Number of Sequences: 37866 Number of extensions: 654382 Number of successful extensions: 1548 Number of sequences better than 10.0: 25 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 1472 Number of HSP's gapped (non-prelim): 31 length of query: 556 length of database: 18,247,518 effective HSP length: 107 effective length of query: 449 effective length of database: 14,195,856 effective search space: 6373939344 effective search space used: 6373939344 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.