Guide to the Human Genome
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Search of human proteins with 57863257

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
         (556 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57863257 T-complex protein 1 isoform a [Homo sapiens]             1068   0.0  
gi|57863259 T-complex protein 1 isoform b [Homo sapiens]              773   0.0  
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo...   302   6e-82
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]       294   2e-79
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom...   286   3e-77
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom...   280   2e-75
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ...   276   3e-74
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom...   267   2e-71
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ...   245   7e-65
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]     242   6e-64
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom...   242   6e-64
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom...   239   4e-63
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho...   181   2e-45
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom...   173   4e-43
gi|7657253 T-complex protein 1 [Homo sapiens]                         122   7e-28
gi|41399285 chaperonin [Homo sapiens]                                  58   2e-08
gi|31542947 chaperonin [Homo sapiens]                                  58   2e-08
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]                   49   9e-06
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]            40   0.007
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]           40   0.007
gi|31543157 glycine-N-acyltransferase-like 1 [Homo sapiens]            33   0.90 
gi|7706322 homeobox prox 1 [Homo sapiens]                              32   1.5  
gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]                    29   9.9  
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 29   9.9  
gi|46048234 nucleolar protein 8 [Homo sapiens]                         29   9.9  

>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
          Length = 556

 Score = 1068 bits (2763), Expect = 0.0
 Identities = 556/556 (100%), Positives = 556/556 (100%)

Query: 1   MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT 60
           MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT
Sbjct: 1   MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT 60

Query: 61  ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG 120
           ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG
Sbjct: 61  ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG 120

Query: 121 YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK 180
           YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK
Sbjct: 121 YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK 180

Query: 181 YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS 240
           YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS
Sbjct: 181 YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS 240

Query: 241 LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF 300
           LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF
Sbjct: 241 LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF 300

Query: 301 VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE 360
           VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE
Sbjct: 301 VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE 360

Query: 361 LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS 420
           LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS
Sbjct: 361 LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS 420

Query: 421 IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER 480
           IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER
Sbjct: 421 IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER 480

Query: 481 KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540
           KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD
Sbjct: 481 KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540

Query: 541 KHGSYEDAVHSGALND 556
           KHGSYEDAVHSGALND
Sbjct: 541 KHGSYEDAVHSGALND 556


>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
          Length = 401

 Score =  773 bits (1996), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 156 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA 215
           MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA
Sbjct: 1   MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA 60

Query: 216 LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERI 275
           LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERI
Sbjct: 61  LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERI 120

Query: 276 QKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 335
           QKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE
Sbjct: 121 QKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 180

Query: 336 GEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDA 395
           GEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDA
Sbjct: 181 GEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDA 240

Query: 396 LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 455
           LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN
Sbjct: 241 LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 300

Query: 456 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK 515
           AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK
Sbjct: 301 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK 360

Query: 516 FATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND 556
           FATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND
Sbjct: 361 FATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND 401


>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
           sapiens]
          Length = 543

 Score =  302 bits (773), Expect = 6e-82
 Identities = 192/537 (35%), Positives = 294/537 (54%), Gaps = 28/537 (5%)

Query: 10  DRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH 69
           D S G      N+ A   IA  V+++LGP G+DK++VD  G  TI+NDGATILKLL+V H
Sbjct: 14  DSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVH 73

Query: 70  PAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAV 129
           PAAK L ++A  QD EVGDGTTSV ++AAE LK     V++ +HP  +I  +R A + AV
Sbjct: 74  PAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAV 133

Query: 130 RYINENLIV--NTDEL-GRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRG 186
             I E  +     D++  R  L   A T++SSK+I     FFA MVVDAV+ +       
Sbjct: 134 NKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMML------- 186

Query: 187 QPRYPVNSVNILKAHGRSQMESMLISGYALN---CVVGSQGMPKRIVNAKIACLDFSLQK 243
                +  + I K  G +  +S L++G A        G +  PK+  N KIA L+  L+ 
Sbjct: 187 DDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL 246

Query: 244 TKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEA 303
              K   ++ +   E    I   E +I  ++++KI  +GA V+L+   I D+  +YF + 
Sbjct: 247 KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADR 306

Query: 304 GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELIL 363
                 RV + DLKR   A G +I +++          A +LG+ +   + +I  +    
Sbjct: 307 DMFCAGRVPEEDLKRTMMACGGSIQTSV------NALSADVLGRCQVFEETQIGGERYNF 360

Query: 364 IKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL 423
                   + + ILRG  +   +E ERSLHDA+ +V+R +++ SVV GGGA+E  LS YL
Sbjct: 361 FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL 420

Query: 424 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL 483
            +Y+ ++  ++QL I  +A++L +IP  L  NA  D+T+++ KLRA H +          
Sbjct: 421 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT------- 473

Query: 484 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540
            W G+D++N    DN +A V+EP +V++ +L  A+EAA  I+ +D+ IK +P S  D
Sbjct: 474 -WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTVD 528


>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
          Length = 535

 Score =  294 bits (752), Expect = 2e-79
 Identities = 193/547 (35%), Positives = 305/547 (55%), Gaps = 30/547 (5%)

Query: 4   PLSVF---GDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVT--ITNDG 58
           P+++F    D    ET R  + + A +I ++VKS+LGP G+DK+L+    D +  +TNDG
Sbjct: 8   PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67

Query: 59  ATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVI 118
           ATILK + V++PAAKVL +++ +QD EVGDGTTSV ++AAELL+ A+ L+ +KIHP ++I
Sbjct: 68  ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127

Query: 119 SGYRLACKEAVRYINENLIVN-TDELG-RDCLINAAKTSMSSKIIGINGDFFANMVVDAV 176
           +G+R A K A   +  + + + +DE+  R  L+N A T++SSK++  + D F  + V+AV
Sbjct: 128 AGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAV 187

Query: 177 LAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIAC 236
           L +K +         + +++I+K  G S  +S L  G+ L+  +G    PKRI NAKI  
Sbjct: 188 LRLKGSG-------NLEAIHIIKKLGGSLADSYLDEGFLLDKKIG-VNQPKRIENAKILI 239

Query: 237 LDFSLQKTKMKL-GVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDM 295
            +  +   K+K+ G +V +    K+ +I   E +  KE++++IL  G N  +    I + 
Sbjct: 240 ANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNY 299

Query: 296 CLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQER 355
             + F  AG MA+       ++R+A  +G  I ST       +  E   LG  + + +  
Sbjct: 300 PEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTF------DHPELVKLGSCKLIEEVM 353

Query: 356 ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAV 415
           I +D+LI         + +I+LRGA   + DE ERSLHDALCV+ + ++    V GGG  
Sbjct: 354 IGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCS 413

Query: 416 EAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQ 475
           E  ++  +   A     +E +A+  +A++L ++P  +A NA  DS DLVA+LRA H+E  
Sbjct: 414 EMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN 473

Query: 476 VNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHP 535
                      GLD+  G   D    G+ E   VK + L  A EAA  ILR+D++IK  P
Sbjct: 474 TT--------AGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAP 525

Query: 536 ESKDDKH 542
             +   H
Sbjct: 526 RKRVPDH 532


>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
           sapiens]
          Length = 545

 Score =  286 bits (733), Expect = 3e-77
 Identities = 181/541 (33%), Positives = 297/541 (54%), Gaps = 17/541 (3%)

Query: 11  RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
           R +G  ++S N+ AA +IA+I+++ LGP  + KML+D +G + +TNDG  IL+ ++V+HP
Sbjct: 16  RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75

Query: 71  AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
           AAK + E++  QD+EVGDGTTSV+I+A E+L  A+  ++Q++HPT VIS YR A  + + 
Sbjct: 76  AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 135

Query: 131 YINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRY 190
            + + + +  D    D ++N   +S+++K I        N+ +DAV  +++ +  G+   
Sbjct: 136 TL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEI 193

Query: 191 PVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLG 249
            +     + K  G    +S ++ G  +N  V    M + I N +I  LD SL+  K +  
Sbjct: 194 DIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQ 253

Query: 250 VQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVR 309
             + IT  E   +I Q E +  ++  + I+    +V++T  GI D+   Y + A   A+R
Sbjct: 254 TDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIR 313

Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369
           RV K D  RIA+A GA I+S    L  ++    A L +      ++I D+    I + K 
Sbjct: 314 RVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTFITDCKD 368

Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429
             + +I+LRGA+  +  E+ER+L DA+ V + VL    +VPGGGA E A++  L   + +
Sbjct: 369 PKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 428

Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489
           M   EQ      A++L VIP TL  N    +  L+  LRA H +       +N +  G++
Sbjct: 429 MTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENCETWGVN 481

Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--KHGSYED 547
              G   D K+ G++EP  VK+++ K A E A+ +LRIDD++  H +  DD  + G   D
Sbjct: 482 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 541

Query: 548 A 548
           A
Sbjct: 542 A 542


>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
           sapiens]
          Length = 544

 Score =  280 bits (717), Expect = 2e-75
 Identities = 180/541 (33%), Positives = 296/541 (54%), Gaps = 18/541 (3%)

Query: 11  RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
           R +G  ++S N+ AA +IA+I+++ LGP  + KML+D +G + +TNDG  IL+ ++V+HP
Sbjct: 16  RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75

Query: 71  AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
           AAK + E++  QD+EVGDGTTSV+I+  E+L  A+  ++Q++HPT VIS YR A  + + 
Sbjct: 76  AAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 134

Query: 131 YINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRY 190
            + + + +  D    D ++N   +S+++K I        N+ +DAV  +++ +  G+   
Sbjct: 135 TL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEI 192

Query: 191 PVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLG 249
            +     + K  G    +S ++ G  +N  V    M + I N +I  LD SL+  K +  
Sbjct: 193 DIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQ 252

Query: 250 VQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVR 309
             + IT  E   +I Q E +  ++  + I+    +V++T  GI D+   Y + A   A+R
Sbjct: 253 TDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIR 312

Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369
           RV K D  RIA+A GA I+S    L  ++    A L +      ++I D+    I + K 
Sbjct: 313 RVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTFITDCKD 367

Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429
             + +I+LRGA+  +  E+ER+L DA+ V + VL    +VPGGGA E A++  L   + +
Sbjct: 368 PKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 427

Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489
           M   EQ      A++L VIP TL  N    +  L+  LRA H +       +N +  G++
Sbjct: 428 MTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENCETWGVN 480

Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--KHGSYED 547
              G   D K+ G++EP  VK+++ K A E A+ +LRIDD++  H +  DD  + G   D
Sbjct: 481 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 540

Query: 548 A 548
           A
Sbjct: 541 A 541


>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
           sapiens]
          Length = 539

 Score =  276 bits (707), Expect = 3e-74
 Identities = 173/532 (32%), Positives = 296/532 (55%), Gaps = 27/532 (5%)

Query: 8   FGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEV 67
           + DR     IR  N+ AA ++A+ +++SLGP G+DKM+ D  GDVTITNDGATILK ++V
Sbjct: 24  YQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQV 83

Query: 68  EHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKE 127
            HPAA++L EL+  QD E GDGTTSVVIIA  LL +  +L+++ IHPT +   ++ A ++
Sbjct: 84  LHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEK 143

Query: 128 AVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQ 187
            +  + + +    +   R+ L+N+A TS++SK++       + M V+AV+  K  D    
Sbjct: 144 GIEILTD-MSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVM--KVIDPATA 200

Query: 188 PRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMK 247
               +  + I+K  G +  +  L+ G  L   V + G+  R+  AKI  + F L   K  
Sbjct: 201 TSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTD 259

Query: 248 LGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGI-----DDMCLKYFVE 302
           +  Q+V++D  ++D++ + E       +++I  TG NV+L    I      D+ L +  +
Sbjct: 260 MDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNK 319

Query: 303 AGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELI 362
              M ++ + + D++ I K  G   ++ +      + F A MLG A E+ +E   +    
Sbjct: 320 MKIMVIKDIEREDIEFICKTIGTKPVAHI------DQFTADMLGSA-ELAEEVNLNGSGK 372

Query: 363 LIKNTKART---SASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAAL 419
           L+K T   +   + +I++RG+N  + +E ERS+HDALCV++ +++ ++++ GGGA E  L
Sbjct: 373 LLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIEL 432

Query: 420 SIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPE 479
           ++ L  Y+ ++   E   +  FA ++ VIP+TLA NA  +    V +LR  H + +    
Sbjct: 433 ALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE---- 488

Query: 480 RKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLI 531
               K  G+++  G   +  +  V +P +V V +L  ATE   +IL+IDD++
Sbjct: 489 ----KTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVV 536


>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
           sapiens]
          Length = 541

 Score =  267 bits (683), Expect = 2e-71
 Identities = 171/524 (32%), Positives = 290/524 (55%), Gaps = 26/524 (4%)

Query: 15  ETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKV 74
           E ++S ++MAA ++AN +++SLGP GLDKM+VD  GDVT+TNDGATIL +++V+H  AK+
Sbjct: 32  EALKS-HIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKL 90

Query: 75  LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRY--- 131
           + EL+  QD E+GDGTT VV++A  LL+ A++L+ + IHP  +  GY  A + A+ +   
Sbjct: 91  MVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDK 150

Query: 132 INENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYP 191
           I+++++V+  +   + LI  AKT++ SK++       A + V+AVL +   + R      
Sbjct: 151 ISDSVLVDIKD--TEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDV---- 204

Query: 192 VNSVNILKAHGR---SQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL 248
                ++K  G+      ++ LI G  ++       MPK++ +AKIA L    +  K K 
Sbjct: 205 --DFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKT 262

Query: 249 GVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAV 308
             ++ +T  E    +++ E +  +E IQ+I  TGAN+ +   G DD      ++    AV
Sbjct: 263 KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAV 322

Query: 309 RRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTK 368
           R V   +++ IA A+G  I+   + L  E+   A ++    + +      D++++I+  K
Sbjct: 323 RWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLV----QEISFGTTKDKMLVIEQCK 378

Query: 369 ARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYAT 428
              + +I +RG N  + +E +RSLHDALCV++ ++    VV GGGA E + ++ +   A 
Sbjct: 379 NSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEAD 438

Query: 429 SMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGL 488
              + EQ A+  FA +L VIP  L+ N+  +    + ++RA     ++NP       +G+
Sbjct: 439 KCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRA-RQVKEMNPA------LGI 491

Query: 489 DLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
           D  +    D KQ  V E  I K + +  AT+    IL+IDD+ K
Sbjct: 492 DCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRK 535


>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
           sapiens]
          Length = 548

 Score =  245 bits (626), Expect = 7e-65
 Identities = 163/521 (31%), Positives = 277/521 (53%), Gaps = 27/521 (5%)

Query: 20  QNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELA 79
           +N+ A   +A   +++ GP G++KM+++ +  + +TND ATIL+ LEV+HPAAK++   +
Sbjct: 31  RNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMAS 90

Query: 80  DLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVN 139
            +Q++EVGDGT  V++ A  LL+ A+EL++  +  + VI GY +AC++A   I  NL+  
Sbjct: 91  HMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKA-HEILPNLVCC 149

Query: 140 TDELGRDC--LINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNI 197
           + +  RD   + +  +TS+ SK  G N  F A ++  A ++I          + V+++ +
Sbjct: 150 SAKNLRDIDEVSSLLRTSIMSKQYG-NEVFLAKLIAQACVSI----FPDSGHFNVDNIRV 204

Query: 198 LKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDP 257
            K  G     S ++ G        ++G    + +AKIA           +    V+I   
Sbjct: 205 CKILGSGISSSSVLHGMVFK--KETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTA 262

Query: 258 EKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLK 317
           E+L    + E ++   +++ I  TGANV++T G + DM L Y  +   M VR   K DL+
Sbjct: 263 EELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLR 322

Query: 318 RIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSAS-II 376
           R+ K  GAT L  L     EE      +G  + V    + D ++++ K+ K   + S I+
Sbjct: 323 RLCKTVGATALPRLTPPVLEE------MGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIV 376

Query: 377 LRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQL 436
           LRG+ D + D++ER++ D +   K +   K +VPGGGA E  L+  + +Y  +    EQ 
Sbjct: 377 LRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQY 436

Query: 437 AIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKP- 495
           AI +FA +   IP  LA N+   + ++++KL A H E   N        +GLD+    P 
Sbjct: 437 AIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKN--------VGLDIEAEVPA 488

Query: 496 -RDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHP 535
            +D  +AG+ +  + K  ++K AT AA+T+LR+D +I   P
Sbjct: 489 VKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKP 529


>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
          Length = 530

 Score =  242 bits (618), Expect = 6e-64
 Identities = 150/523 (28%), Positives = 277/523 (52%), Gaps = 33/523 (6%)

Query: 21  NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80
           N+ AA  + ++++++LGP G  KMLV   GD+ +T DG  +L  ++++HP A ++ ++A 
Sbjct: 23  NICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVAT 82

Query: 81  LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140
            QD   GDGTTS V+I  ELLK AD  + + +HP  +  G+  A  +A+  + E  +  T
Sbjct: 83  AQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEE--VKVT 140

Query: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNIL 198
            E+ R  L++ A+TS+ +K+     D    +VVD+VLA++      +P YP++   V I+
Sbjct: 141 KEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR------RPGYPIDLFMVEIM 194

Query: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258
           +   +   ++ LI G  L+       M KR+ +A I   + SL+  K ++         E
Sbjct: 195 EMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAE 254

Query: 259 KLDQIRQRESDITKERIQKIL---------ATGANVILTTGGIDDMCLKYFVEAGAMAVR 309
           + +++ + E    ++R+QKI+         +    V++   GID   L    + G +A+R
Sbjct: 255 EKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALR 314

Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369
           R  +R+++R++ A G   +++  +L  +       LG A  V +  + +++   I+    
Sbjct: 315 RAKRRNMERLSLACGGMAVNSFEDLTVD------CLGHAGLVYEYTLGEEKFTFIEECVN 368

Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429
             S +++++G N     +++ ++ D L  +K  +E   +VPG GA+E A++  L  Y  S
Sbjct: 369 PCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNS 428

Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489
           +  R +L +  FA +LL+IP  LA NA  D  + + K++A H E++        + +G+D
Sbjct: 429 IKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESK--------QLVGVD 480

Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
           L+ G+P     AGV++   VK + L   T  A  IL +D++++
Sbjct: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 523


>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
           sapiens]
          Length = 531

 Score =  242 bits (618), Expect = 6e-64
 Identities = 150/521 (28%), Positives = 279/521 (53%), Gaps = 29/521 (5%)

Query: 21  NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80
           N+ AA  + ++++++LGP G  KMLV   GD+ +T DG  +L  ++++HP A ++ ++A 
Sbjct: 23  NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82

Query: 81  LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140
            QD   GDGTTS V+I  ELLK AD  + + +HP  +  G+  A ++A++++ E  +  +
Sbjct: 83  AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEE--VKVS 140

Query: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKA 200
            E+ R+ LI+ A+TS+ +K+     D     VVD++LAIK  D   +P   +  + I++ 
Sbjct: 141 REMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EP-IDLFMIEIMEM 196

Query: 201 HGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKL 260
             +S+ ++ LI G  L+       M KR+ +A I   + SL+  K ++         E+ 
Sbjct: 197 KHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEER 256

Query: 261 DQIRQRESDITKERIQKIL---------ATGANVILTTGGIDDMCLKYFVEAGAMAVRRV 311
           +++ + E    ++R++KI+         +    V++   GID   L    + G +A+RR 
Sbjct: 257 EKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRA 316

Query: 312 LKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKART 371
            +R+++R+  A G   L++  +L  +       LG A  V +  + +++   I+      
Sbjct: 317 KRRNMERLTLACGGVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNNPR 370

Query: 372 SASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMG 431
           S +++++G N     +++ ++ D L  VK  ++   VVPG GAVE A++  L  +  S+ 
Sbjct: 371 SVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVK 430

Query: 432 SREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLS 491
            R QL +  FA +LL+IP  LA N+  D  + + K++A H+E+         + +G+DL+
Sbjct: 431 GRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVDLN 482

Query: 492 NGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
            G+P    + GV++   VK + L   T  A  IL +D++++
Sbjct: 483 TGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 523


>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
           sapiens]
          Length = 507

 Score =  239 bits (611), Expect = 4e-63
 Identities = 158/487 (32%), Positives = 259/487 (53%), Gaps = 17/487 (3%)

Query: 65  LEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLA 124
           ++V+HPAAK + E++  QD+EVGDGTTSV+I+A E+L  A+  ++Q++HPT VIS YR A
Sbjct: 32  IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91

Query: 125 CKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDI 184
             + +  + + + +  D    D ++N   +S+++K I        N+ +DAV  +++ + 
Sbjct: 92  LDDMISTL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE- 149

Query: 185 RGQPRYPVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQK 243
            G+    +     + K  G    +S ++ G  +N  V    M + I N +I  LD SL+ 
Sbjct: 150 NGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY 209

Query: 244 TKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEA 303
            K +    + IT  E   +I Q E +  ++  + I+    +V++T  GI D+   Y + A
Sbjct: 210 KKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRA 269

Query: 304 GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELIL 363
              A+RRV K D  RIA+A GA I+S    L  ++    A L +      ++I D+    
Sbjct: 270 NITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTF 324

Query: 364 IKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL 423
           I + K   + +I+LRGA+  +  E+ER+L DA+ V + VL    +VPGGGA E A++  L
Sbjct: 325 ITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHAL 384

Query: 424 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL 483
              + +M   EQ      A++L VIP TL  N    +  L+  LRA H +       +N 
Sbjct: 385 TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENC 437

Query: 484 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--K 541
           +  G++   G   D K+ G++EP  VK+++ K A E A+ +LRIDD++  H +  DD  +
Sbjct: 438 ETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSR 497

Query: 542 HGSYEDA 548
            G   DA
Sbjct: 498 QGGAPDA 504


>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
           sapiens]
          Length = 486

 Score =  181 bits (459), Expect = 2e-45
 Identities = 132/523 (25%), Positives = 250/523 (47%), Gaps = 78/523 (14%)

Query: 21  NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80
           N+ AA  + ++++++LGP G  KMLV   GD+ +T DG  +L                  
Sbjct: 23  NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLH----------------- 65

Query: 81  LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140
               E+G                        +HP  +  G+  A ++A++++ E  +  +
Sbjct: 66  ----EMG------------------------LHPRIITEGFEAAKEKALQFLEEVKV--S 95

Query: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNIL 198
            E+ R+ LI+ A+TS+ +K+     D     VVD++LAIK  D       P++   + I+
Sbjct: 96  REMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD------EPIDLFMIEIM 149

Query: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258
           +   +S+ ++ LI G  L+       M KR+ +A I   + SL+  K ++         E
Sbjct: 150 EMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAE 209

Query: 259 KLDQIRQRESDITKERIQKILATGANV---------ILTTGGIDDMCLKYFVEAGAMAVR 309
           + +++ + E    ++R++KI+     V         ++   GID   L    + G +A+R
Sbjct: 210 EREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALR 269

Query: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369
           R  +R+++R+  A G   L++  +L  +       LG A  V +  + +++   I+    
Sbjct: 270 RAKRRNMERLTLACGGVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNN 323

Query: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429
             S +++++G N     +++ ++ D L  VK  ++   VVPG GAVE A++  L  +  S
Sbjct: 324 PRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPS 383

Query: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489
           +  R QL +  FA +LL+IP  LA N+  D  + + K++A H+E+         + +G+D
Sbjct: 384 VKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVD 435

Query: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
           L+ G+P    + GV++   VK + L   T  A  IL +D++++
Sbjct: 436 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 478


>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
           sapiens]
          Length = 339

 Score =  173 bits (438), Expect = 4e-43
 Identities = 109/338 (32%), Positives = 182/338 (53%), Gaps = 18/338 (5%)

Query: 206 MESMLISGYALN---CVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQ 262
           M+S L++G A        G +  PK+  N KIA L+  L+    K   ++ +   E    
Sbjct: 2   MDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQA 61

Query: 263 IRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKA 322
           I   E +I  ++++KI  +GA V+L+   I D+  +YF +       RV + DLKR   A
Sbjct: 62  IVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMA 121

Query: 323 SGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGAND 382
            G +I +++  L  +      +LG+ +   + +I  +            + + ILRG  +
Sbjct: 122 CGGSIQTSVNALSAD------VLGRCQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAE 175

Query: 383 FMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFA 442
              +E ERSLHDA+ +V+R +++ SVV GGGA+E  LS YL +Y+ ++  ++QL I  +A
Sbjct: 176 QFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYA 235

Query: 443 RSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAG 502
           ++L +IP  L  NA  D+T+++ KLRA H +           W G+D++N    DN +A 
Sbjct: 236 KALEIIPRQLCDNAGFDATNILNKLRARHAQGGT--------WYGVDINNEDIADNFEAF 287

Query: 503 VFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD 540
           V+EP +V++ +L  A+EAA  I+ +D+ IK +P S  D
Sbjct: 288 VWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTVD 324


>gi|7657253 T-complex protein 1 [Homo sapiens]
          Length = 557

 Score =  122 bits (307), Expect = 7e-28
 Identities = 113/514 (21%), Positives = 221/514 (42%), Gaps = 31/514 (6%)

Query: 21  NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80
           ++ A  ++A++++   GP G  K LV   G+   T     IL+ LE+EHPAA +L E   
Sbjct: 36  SLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAGQ 95

Query: 81  LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140
            Q +  GDGT  VV++   LL+ A++L+K  +    +   Y  A  E +  +    I + 
Sbjct: 96  TQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAIQSL 155

Query: 141 DELGRD--CLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNIL 198
             L      L +   T   S +     D    +V  A  AIK  D   +P      V + 
Sbjct: 156 GPLEDPSWALHSVMNTHTLSPM-----DHLTKLVAHACWAIKELDGSFKP----ERVGVC 206

Query: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258
              G +  +S L+ G A++  +  Q M   +  A++A                  ++ P 
Sbjct: 207 ALPGGTLEDSCLLPGLAISGKLCGQ-MATVLSGARVALFACPFGPAHPNAPATARLSSPA 265

Query: 259 KLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKR 318
            L Q  +    + ++++ ++ A G NV +  G +D+  L    + G + ++     ++  
Sbjct: 266 DLAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQARSWMEIIY 325

Query: 319 IAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSA-SIIL 377
           +++     +L  L              G+ + V ++ + D   ++ +     T A +++L
Sbjct: 326 LSEVLDTPLLPRL--------LPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTVVL 377

Query: 378 RGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLA 437
           RGA        E++++  +    ++ +   ++PG GA E AL+  L +  + +      A
Sbjct: 378 RGATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPA 437

Query: 438 IAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRD 497
              FA +L  +P TLA NA    +D++A++   H    +      L  +G +       +
Sbjct: 438 FLAFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNL------LMGVGTE----GIIN 487

Query: 498 NKQAGVFEPTIVKVKSLKFATEAAITILRIDDLI 531
             Q GV++  IVK +  +   E  + ++ +D+++
Sbjct: 488 VAQEGVWDTLIVKAQGFRAVAEVVLQLVTVDEIV 521


>gi|41399285 chaperonin [Homo sapiens]
          Length = 573

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 107/567 (18%), Positives = 222/567 (39%), Gaps = 76/567 (13%)

Query: 10  DRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH 69
           D   G   R+  +     +A+ V  ++GP G   ++    G   +T DG T+ K ++++ 
Sbjct: 29  DVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKD 88

Query: 70  P----AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLAC 125
                 AK++ ++A+  ++E GDGTT+  ++A  + K   E + +  +P  +  G  LA 
Sbjct: 89  KYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAV 148

Query: 126 KEAVRYINE---------------NLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFAN 170
              +  + +                +  N D+   + + +A K      +I +      N
Sbjct: 149 DAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN 208

Query: 171 MVVDAVLAIKY----------TDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVV 220
             ++ +  +K+             +GQ     ++  +L     S ++S++    AL  + 
Sbjct: 209 DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV---PALE-IA 264

Query: 221 GSQGMPKRIVNAKIACLDFS-LQKTKMKLGVQVV-ITDPEKLDQIRQRESDITKERIQKI 278
            +   P  I+   +     S L   ++K+G+QVV +  P   D  + +  D+        
Sbjct: 265 NAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMA------- 317

Query: 279 LATGANVILTTG---GIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 335
           +ATG  V    G    ++D+      + G +    ++ +D   + K  G          E
Sbjct: 318 IATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IVTKDDAMLLKGKGDKAQIEKRIQE 373

Query: 336 GEETFEAAMLGQAEEVVQERIC--DDELILIKNTKARTSASIILRGANDFMCDEMERSLH 393
             E  +       +E + ER+    D + ++K           + G +D   +E +  + 
Sbjct: 374 IIEQLDVTTSEYEKEKLNERLAKLSDGVAVLK-----------VGGTSDVEVNEKKDRVT 422

Query: 394 DALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLA 453
           DAL   +  +E   V+ GG A+   +     +  T     +++ I    R+L +   T+A
Sbjct: 423 DALNATRAAVEEGIVLGGGCALLRCIPAL--DSLTPANEDQKIGIEIIKRTLKIPAMTIA 480

Query: 454 VNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKS 513
            NA  + + +V K+    +E            +G D   G   +  + G+ +PT V   +
Sbjct: 481 KNAGVEGSLIVEKIMQSSSE------------VGYDAMAGDFVNMVEKGIIDPTKVVRTA 528

Query: 514 LKFATEAAITILRIDDLIKLHPESKDD 540
           L  A   A  +   + ++   P+ + D
Sbjct: 529 LLDAAGVASLLTTAEVVVTEIPKEEKD 555


>gi|31542947 chaperonin [Homo sapiens]
          Length = 573

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 107/567 (18%), Positives = 222/567 (39%), Gaps = 76/567 (13%)

Query: 10  DRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH 69
           D   G   R+  +     +A+ V  ++GP G   ++    G   +T DG T+ K ++++ 
Sbjct: 29  DVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKD 88

Query: 70  P----AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLAC 125
                 AK++ ++A+  ++E GDGTT+  ++A  + K   E + +  +P  +  G  LA 
Sbjct: 89  KYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAV 148

Query: 126 KEAVRYINE---------------NLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFAN 170
              +  + +                +  N D+   + + +A K      +I +      N
Sbjct: 149 DAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN 208

Query: 171 MVVDAVLAIKY----------TDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVV 220
             ++ +  +K+             +GQ     ++  +L     S ++S++    AL  + 
Sbjct: 209 DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV---PALE-IA 264

Query: 221 GSQGMPKRIVNAKIACLDFS-LQKTKMKLGVQVV-ITDPEKLDQIRQRESDITKERIQKI 278
            +   P  I+   +     S L   ++K+G+QVV +  P   D  + +  D+        
Sbjct: 265 NAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMA------- 317

Query: 279 LATGANVILTTG---GIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLE 335
           +ATG  V    G    ++D+      + G +    ++ +D   + K  G          E
Sbjct: 318 IATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IVTKDDAMLLKGKGDKAQIEKRIQE 373

Query: 336 GEETFEAAMLGQAEEVVQERIC--DDELILIKNTKARTSASIILRGANDFMCDEMERSLH 393
             E  +       +E + ER+    D + ++K           + G +D   +E +  + 
Sbjct: 374 IIEQLDVTTSEYEKEKLNERLAKLSDGVAVLK-----------VGGTSDVEVNEKKDRVT 422

Query: 394 DALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLA 453
           DAL   +  +E   V+ GG A+   +     +  T     +++ I    R+L +   T+A
Sbjct: 423 DALNATRAAVEEGIVLGGGCALLRCIPAL--DSLTPANEDQKIGIEIIKRTLKIPAMTIA 480

Query: 454 VNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKS 513
            NA  + + +V K+    +E            +G D   G   +  + G+ +PT V   +
Sbjct: 481 KNAGVEGSLIVEKIMQSSSE------------VGYDAMAGDFVNMVEKGIIDPTKVVRTA 528

Query: 514 LKFATEAAITILRIDDLIKLHPESKDD 540
           L  A   A  +   + ++   P+ + D
Sbjct: 529 LLDAAGVASLLTTAEVVVTEIPKEEKD 555


>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
          Length = 723

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 4/98 (4%)

Query: 21  NVMAAASIAN----IVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLC 76
           +V AA  +A     IV   +GP G   +     G+V ++ +G  +L+ L +EHP A+++ 
Sbjct: 10  SVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIV 69

Query: 77  ELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHP 114
           +      K+ GDG  + +I    LL+    +  ++  P
Sbjct: 70  DCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDP 107



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 21/132 (15%)

Query: 408 VVPGGGAVEAALSIYLENYATSMGSREQLAIAE-FARSLLVIPNTLAVNAAQDSTDLVAK 466
           V+P GG  E  L  YL NYA      E+  ++   A +LL IP  L  +     +     
Sbjct: 599 VLPVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTY 658

Query: 467 LRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILR 526
           +RA H                  L   +P  + Q G+ E  + K + L    +    IL 
Sbjct: 659 IRAVH-----------------ALQTNQPLVSSQTGL-ESVMGKYQLLTSVLQCLTKILT 700

Query: 527 IDDLI--KLHPE 536
           ID +I  K HP+
Sbjct: 701 IDMVITVKRHPQ 712


>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
          Length = 570

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 82/430 (19%), Positives = 162/430 (37%), Gaps = 40/430 (9%)

Query: 15  ETIRSQNVMAAASIAN-IVKSSLGPVGLDKMLVDDIGD-VTITNDGATILKLLEVEHPAA 72
           E + ++ V    S+   IV S  GP G  K L +  G  V  T+  + +L  L V HP  
Sbjct: 15  EPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPIL 74

Query: 73  KVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYI 132
           K+L            D      I+   L++N   L    + PT+VI   +      + Y+
Sbjct: 75  KILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYL 131

Query: 133 NENLI---VNTDELGRDCLINAAKTSMSSK----IIGINGDFFANMVVDAVLAIKYTDIR 185
                   +  D      L+   ++ ++SK    +     +  + +++ A L     +  
Sbjct: 132 KSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAE 191

Query: 186 GQPRYPVNSVNILKAHGRSQMESMLISGYALNC--VVGSQGMP-KRIVNAKIACLDFSLQ 242
           G     +    I+   G+  ++S ++ G  +    V   + +P K+    K+A    +L 
Sbjct: 192 G--HIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLS 249

Query: 243 KTKMKLGVQVVIT------DPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMC 296
                 G   V+       +   LDQ+      +  + +  +L            +    
Sbjct: 250 GDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQ---------KVIHPS 300

Query: 297 LKYFVEA-GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQER 355
           LK F+     +A+ R+    ++ + K +G   + +L ++           G  ++V   +
Sbjct: 301 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNS------YGSVKDVCTAK 354

Query: 356 ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAV 415
                   +   +A T  S++L   ND   DE++ +   AL V++  L+    + GGG  
Sbjct: 355 FGSKHFFHLIPNEA-TICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCT 413

Query: 416 EAALSIYLEN 425
           E  L+ Y+ +
Sbjct: 414 ETHLAAYIRH 423


>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
          Length = 570

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 82/430 (19%), Positives = 162/430 (37%), Gaps = 40/430 (9%)

Query: 15  ETIRSQNVMAAASIAN-IVKSSLGPVGLDKMLVDDIGD-VTITNDGATILKLLEVEHPAA 72
           E + ++ V    S+   IV S  GP G  K L +  G  V  T+  + +L  L V HP  
Sbjct: 15  EPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPIL 74

Query: 73  KVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYI 132
           K+L            D      I+   L++N   L    + PT+VI   +      + Y+
Sbjct: 75  KILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYL 131

Query: 133 NENLI---VNTDELGRDCLINAAKTSMSSK----IIGINGDFFANMVVDAVLAIKYTDIR 185
                   +  D      L+   ++ ++SK    +     +  + +++ A L     +  
Sbjct: 132 KSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAE 191

Query: 186 GQPRYPVNSVNILKAHGRSQMESMLISGYALNC--VVGSQGMP-KRIVNAKIACLDFSLQ 242
           G     +    I+   G+  ++S ++ G  +    V   + +P K+    K+A    +L 
Sbjct: 192 G--HIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLS 249

Query: 243 KTKMKLGVQVVIT------DPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMC 296
                 G   V+       +   LDQ+      +  + +  +L            +    
Sbjct: 250 GDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQ---------KVIHPS 300

Query: 297 LKYFVEA-GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQER 355
           LK F+     +A+ R+    ++ + K +G   + +L ++           G  ++V   +
Sbjct: 301 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNS------YGSVKDVCTAK 354

Query: 356 ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAV 415
                   +   +A T  S++L   ND   DE++ +   AL V++  L+    + GGG  
Sbjct: 355 FGSKHFFHLIPNEA-TICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCT 413

Query: 416 EAALSIYLEN 425
           E  L+ Y+ +
Sbjct: 414 ETHLAAYIRH 423


>gi|31543157 glycine-N-acyltransferase-like 1 [Homo sapiens]
          Length = 333

 Score = 32.7 bits (73), Expect = 0.90
 Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 13/148 (8%)

Query: 375 IILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSRE 434
           +I+R     M D+M+   +      K   +S+ V+     V     + ++    S+G  E
Sbjct: 86  VIIRPQKQEMTDDMDSYTNVYRMFSKEPQKSEEVLKNCEIVNWKQRLQIQGLQESLG--E 143

Query: 435 QLAIAEFARS---------LLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKW 485
            + +A F++S         LLV  + L +NA+  S  L +     H + +   E  N K+
Sbjct: 144 GIRVATFSKSVKVEHSRALLLVTEDILKLNASSKSK-LGSWAETGHPDDEFESETPNFKY 202

Query: 486 IGLDLS-NGKPRDNKQAGVFEPTIVKVK 512
             LD+S +G   DN + G  E ++  +K
Sbjct: 203 AQLDVSYSGLVNDNWKRGKNERSLHYIK 230


>gi|7706322 homeobox prox 1 [Homo sapiens]
          Length = 244

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 12/76 (15%)

Query: 25  AASIANIVKSSLGPVGLDKMLVD-DIGDVTITNDGATILKLLEVEHPAAKVLCELADLQD 83
           A + AN  K  L PV LDK ++  D GD  + N+ A IL+LL +E        EL +LQ 
Sbjct: 168 AVAKANQTKEGL-PVALDKHILGFDTGDAVL-NEAAQILRLLHIE--------ELRELQT 217

Query: 84  KEVGDGTTSVVIIAAE 99
           K + +   +V  I A+
Sbjct: 218 K-INEAIVAVQAIIAD 232


>gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]
          Length = 1453

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 25/120 (20%), Positives = 51/120 (42%), Gaps = 28/120 (23%)

Query: 200  AHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL----------- 248
            AH R ++E ++I  Y      GS G  K + +  I  L+ ++ + + +L           
Sbjct: 1227 AHERIRLEQLIIDSYEKQQAQGS-GRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLEDL 1285

Query: 249  GVQVVITDPE----------------KLDQIRQRESDITKERIQKILATGANVILTTGGI 292
            G++ V  D                  + +++R+  S +TK  +++ +     ++ TTGGI
Sbjct: 1286 GLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGGI 1345


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 33/174 (18%), Positives = 75/174 (43%), Gaps = 11/174 (6%)

Query: 323  SGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGAND 382
            +G  ++ T ++   +++ E A +   ++++   +CD E ++    K+  S S +L   ++
Sbjct: 1470 AGLPVIKTSSSQHSDKS-EEARVEDKQDLLFSTVCDSERLVSSQKKSLMSTSEVLEPEHE 1528

Query: 383  F---MCDEMERSLHDALCVVKRVLESKSVVPGGGAVE-AALSIYLENYATSMGSREQLAI 438
                +  E+++   +          SK ++P G   E A+ S  LEN A+ +     L  
Sbjct: 1529 LPLSLWGEIKKKETELPSSQNVSPASKHIIPKGKDEETASSSPELENLASGLAPTLLLLS 1588

Query: 439  AEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSN 492
             +  +  + + +T   +   +  D+         E  + PE+K+     L+L N
Sbjct: 1589 DDKNKPAVEVSSTAQGDFPSEKQDVALA------ELSLEPEKKDKPHQPLELPN 1636


>gi|46048234 nucleolar protein 8 [Homo sapiens]
          Length = 1167

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 10/80 (12%)

Query: 223 QGMPKRI---VNAKIACLDFS-----LQKTKMKLG-VQVVITDPEKLDQIRQRESDITKE 273
           QG P+++   +N  +A  D       L KTK K G +Q+ +     L ++ Q E +  K 
Sbjct: 46  QGNPQKVFAYINISVAEADLKKCMSVLNKTKWKGGTLQIQLAKESFLHRLAQ-EREAAKA 104

Query: 274 RIQKILATGANVILTTGGID 293
           + ++     AN++  TGG+D
Sbjct: 105 KKEESTTGNANLLEKTGGVD 124


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,241,762
Number of Sequences: 37866
Number of extensions: 654382
Number of successful extensions: 1548
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1472
Number of HSP's gapped (non-prelim): 31
length of query: 556
length of database: 18,247,518
effective HSP length: 107
effective length of query: 449
effective length of database: 14,195,856
effective search space: 6373939344
effective search space used: 6373939344
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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