BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|57529222 basic helix-loop-helix domain containing, class B, 4 [Homo sapiens] (225 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|57529222 basic helix-loop-helix domain containing, class B, 4... 452 e-127 gi|22748877 basic helix-loop-helix domain containing, class B, 5... 177 5e-45 gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 105 2e-23 gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] 102 2e-22 gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] 84 7e-17 gi|98986461 neurogenic differentiation 2 [Homo sapiens] 78 7e-15 gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 74 8e-14 gi|27475985 neurogenic differentiation 6 [Homo sapiens] 72 5e-13 gi|38455396 neurogenin 1 [Homo sapiens] 70 1e-12 gi|153792190 neurogenic differentiation 4 [Homo sapiens] 70 2e-12 gi|121114306 neurogenic differentiation 1 [Homo sapiens] 69 2e-12 gi|68989258 neurogenin 3 [Homo sapiens] 61 7e-10 gi|31077092 neurogenin 2 [Homo sapiens] 60 2e-09 gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 59 3e-09 gi|226498192 atonal homolog 8 [Homo sapiens] 56 3e-08 gi|23097242 nephew of atonal 3 [Homo sapiens] 53 2e-07 gi|4885075 atonal homolog 1 [Homo sapiens] 53 2e-07 gi|4507741 twist [Homo sapiens] 52 3e-07 gi|148922889 scleraxis homolog B [Homo sapiens] 52 4e-07 gi|186972126 scleraxis homolog A [Homo sapiens] 52 4e-07 gi|17981708 twist homolog 2 [Homo sapiens] 51 9e-07 gi|21553337 atonal homolog 7 [Homo sapiens] 50 1e-06 gi|48255909 basic helix-loop-helix transcription factor 15 [Homo... 50 2e-06 gi|116805332 musculin [Homo sapiens] 50 2e-06 gi|239756681 PREDICTED: basic helix-loop-helix family, member a9... 46 2e-05 gi|239751178 PREDICTED: basic helix-loop-helix family, member a9... 46 2e-05 gi|239745666 PREDICTED: basic helix-loop-helix family, member a9... 46 2e-05 gi|38202237 transcription factor 21 [Homo sapiens] 45 4e-05 gi|38202239 transcription factor 21 [Homo sapiens] 45 4e-05 gi|12545384 basic helix-loop-helix transcription factor HAND2 [H... 44 9e-05 >gi|57529222 basic helix-loop-helix domain containing, class B, 4 [Homo sapiens] Length = 225 Score = 452 bits (1162), Expect = e-127 Identities = 225/225 (100%), Positives = 225/225 (100%) Query: 1 MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQ 60 MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQ Sbjct: 1 MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQ 60 Query: 61 AAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDAL 120 AAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDAL Sbjct: 61 AAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDAL 120 Query: 121 DGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNA 180 DGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNA Sbjct: 121 DGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNA 180 Query: 181 APLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP 225 APLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP Sbjct: 181 APLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP 225 >gi|22748877 basic helix-loop-helix domain containing, class B, 5 [Homo sapiens] Length = 381 Score = 177 bits (450), Expect = 5e-45 Identities = 115/226 (50%), Positives = 133/226 (58%), Gaps = 38/226 (16%) Query: 18 GYAAAAAGLA----YGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDED 73 G A AA G + +G A P G G G GG + SG SG Sbjct: 176 GGAKAAEGCSNAHLHGGASVPPGGLGGG--GGGGSSSGSSG------GGGGSGSGSGGSS 227 Query: 74 DAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSP 133 S++ ++ +EQ++LRL+INARERRRMHDLNDALD LRAVIPYAHSP Sbjct: 228 S------------SSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSP 275 Query: 134 SVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGL---------AAPVNAAPLT 184 SVRKLSKIATLLLAKNYILMQAQAL+EMRRLVA+LNQGQ + AA AA L Sbjct: 276 SVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALH 335 Query: 185 P----FGQATVCPFSAG-AALGPCPDKCAAFSGTPSALCKHCHEKP 225 P + QA PFSAG CP+KCA F+ S+LCK C EKP Sbjct: 336 PALGAYEQAAGYPFSAGLPPAASCPEKCALFNSVSSSLCKQCTEKP 381 >gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo sapiens] Length = 323 Score = 105 bits (263), Expect = 2e-23 Identities = 60/107 (56%), Positives = 73/107 (68%), Gaps = 4/107 (3%) Query: 97 EQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQ 156 E + LRL IN+RER+RMHDLN A+DGLR V+PYAH PSVRKLSKIATLLLA+NYILM Sbjct: 105 ELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTN 164 Query: 157 ALDEMRRLVAFLNQGQGLAAPVNA----APLTPFGQATVCPFSAGAA 199 +L+EM+RLV+ + G +A A P AT P +A A Sbjct: 165 SLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHA 211 >gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] Length = 272 Score = 102 bits (255), Expect = 2e-22 Identities = 51/76 (67%), Positives = 62/76 (81%) Query: 96 REQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQA 155 ++ + LRL IN RER+RMHDLN A+DGLR V+PYAH PSVRKLSKIATLLLA+NYILM Sbjct: 79 QDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLT 138 Query: 156 QALDEMRRLVAFLNQG 171 +L+EM+RLV + G Sbjct: 139 SSLEEMKRLVGEIYGG 154 >gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] Length = 271 Score = 84.3 bits (207), Expect = 7e-17 Identities = 71/163 (43%), Positives = 86/163 (52%), Gaps = 28/163 (17%) Query: 55 PRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAAD--GRRRP----REQRSLRLSINAR 108 P+A + E+ E G GPGS A G RP +Q+ LR IN+R Sbjct: 66 PKAAREKPEAPAEPPGP------------GPGSGAHPGGSARPDAKEEQQQQLRRKINSR 113 Query: 109 ERRRMHDLNDALDGLRAVI-PY--AHSPSV--RKLSKIATLLLAKNYILMQAQALDEMRR 163 ER+RM DLN A+D LR VI PY AH RKLSKIATLLLA+NYIL+ +L E+RR Sbjct: 114 ERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRR 173 Query: 164 LVAFLNQGQGLAAP-VNAAPLTPFGQATVCPFSAGAALGPCPD 205 L +G G AAP + A L A A A+GP PD Sbjct: 174 A---LGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGP-PD 212 >gi|98986461 neurogenic differentiation 2 [Homo sapiens] Length = 382 Score = 77.8 bits (190), Expect = 7e-15 Identities = 59/158 (37%), Positives = 78/158 (49%), Gaps = 25/158 (15%) Query: 43 PGPGGDLPAAPAPRAPAQAAESS----------GEQSGDE----------DDAFEQRRRR 82 PGPG PA A P + E + GE G+E D+A +R ++ Sbjct: 44 PGPGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKK 103 Query: 83 RGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIA 142 RGP + R + R NARER RMHDLN ALD LR V+P +KLSKI Sbjct: 104 RGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPC--YSKTQKLSKIE 161 Query: 143 TLLLAKNYILMQAQALDEMRR--LVAFLNQ-GQGLAAP 177 TL LAKNYI ++ L +R LV+++ +GL+ P Sbjct: 162 TLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQP 199 >gi|29126247 basic helix-loop-helix family, member a15 [Homo sapiens] Length = 189 Score = 74.3 bits (181), Expect = 8e-14 Identities = 58/120 (48%), Positives = 67/120 (55%), Gaps = 10/120 (8%) Query: 32 REPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADG 91 ++ EA G GTP G LP P P PA+ S ++ E RRRR GP S G Sbjct: 15 QDTEATPGEGTPD--GSLPN-PGPE-PAKGLRSRPARAAARAPG-EGRRRRPGP-SGPGG 68 Query: 92 RRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151 RR QR RL N RER+RMH LN+A LR VIP H + +KLSKI TL LAKNYI Sbjct: 69 RRDSSIQR--RLESNERERQRMHKLNNAFQALREVIP--HVRADKKLSKIETLTLAKNYI 124 >gi|27475985 neurogenic differentiation 6 [Homo sapiens] Length = 337 Score = 71.6 bits (174), Expect = 5e-13 Identities = 51/125 (40%), Positives = 66/125 (52%), Gaps = 5/125 (4%) Query: 56 RAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHD 115 RAP + E E+ E++ RRRG + R + R NARER RMH Sbjct: 50 RAPGEETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHG 109 Query: 116 LNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR--LVAFL-NQGQ 172 LNDALD LR V+P +KLSKI TL LAKNYI ++ L +R L+ F+ N + Sbjct: 110 LNDALDNLRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCK 167 Query: 173 GLAAP 177 GL+ P Sbjct: 168 GLSQP 172 >gi|38455396 neurogenin 1 [Homo sapiens] Length = 237 Score = 70.5 bits (171), Expect = 1e-12 Identities = 51/116 (43%), Positives = 62/116 (53%), Gaps = 18/116 (15%) Query: 50 PAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQ-------RSLR 102 P APA R + +S E G +DD E+RRRR GR R R + RS R Sbjct: 44 PPAPARRGAPNISRAS-EVPGAQDDEQERRRRR--------GRTRVRSEALLHSLRRSRR 94 Query: 103 LSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 158 + N RER RMH+LN ALD LR+V+P P KL+KI TL A NYI A+ L Sbjct: 95 VKANDRERNRMHNLNAALDALRSVLP--SFPDDTKLTKIETLRFAYNYIWALAETL 148 >gi|153792190 neurogenic differentiation 4 [Homo sapiens] Length = 331 Score = 69.7 bits (169), Expect = 2e-12 Identities = 42/97 (43%), Positives = 58/97 (59%), Gaps = 4/97 (4%) Query: 63 ESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDG 122 +S E+ +E+D ++ +RRGP + R R+ R+ NARER RMH LNDALD Sbjct: 52 DSIEEEEEEEEDG--EKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDN 109 Query: 123 LRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALD 159 LR V+P +KLSKI TL LA+NYI ++ L+ Sbjct: 110 LRRVMPC--YSKTQKLSKIETLRLARNYIWALSEVLE 144 >gi|121114306 neurogenic differentiation 1 [Homo sapiens] Length = 356 Score = 69.3 bits (168), Expect = 2e-12 Identities = 47/118 (39%), Positives = 66/118 (55%), Gaps = 5/118 (4%) Query: 63 ESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDG 122 E E+ +E++ +Q+ +RRGP + R + R+ NARER RMH LN ALD Sbjct: 64 EDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDN 123 Query: 123 LRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR--LVAFLNQ-GQGLAAP 177 LR V+P +KLSKI TL LAKNYI ++ L + LV+F+ +GL+ P Sbjct: 124 LRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQP 179 >gi|68989258 neurogenin 3 [Homo sapiens] Length = 214 Score = 61.2 bits (147), Expect = 7e-10 Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 16/113 (14%) Query: 54 APRAPAQAAESSGE-QSGDEDDAFEQRRRRRGPGSAADGRRRPR-------EQRSLRLSI 105 AP +P + + E + G A + R RRG GR RP+ ++RS R Sbjct: 35 APPSPTRTRGNCAEAEEGGCRGAPRKLRARRG------GRSRPKSELALSKQRRSRRKKA 88 Query: 106 NARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 158 N RER RMH+LN ALD LR V+P P KL+KI TL A NYI Q L Sbjct: 89 NDRERNRMHNLNSALDALRGVLP--TFPDDAKLTKIETLRFAHNYIWALTQTL 139 >gi|31077092 neurogenin 2 [Homo sapiens] Length = 272 Score = 60.1 bits (144), Expect = 2e-09 Identities = 67/209 (32%), Positives = 83/209 (39%), Gaps = 56/209 (26%) Query: 51 AAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGP-----------------------GS 87 A+PA A + S+ E+ +E A RR+RG G Sbjct: 23 ASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGL 82 Query: 88 AADGRRRPREQRSL-----------------RLSINARERRRMHDLNDALDGLRAVIPYA 130 D +RRP R++ RL N RER RMH+LN ALD LR V+P Sbjct: 83 VHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP-- 140 Query: 131 HSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQAT 190 P KL+KI TL A NYI AL E RL G G P F +A Sbjct: 141 TFPEDAKLTKIETLRFAHNYI----WALTETLRLADHCGGGGG------GLPGALFSEAV 190 Query: 191 -VCPFSAGAAL---GPCPDKCAAFSGTPS 215 + P A AAL G P + +S T S Sbjct: 191 LLSPGGASAALSSSGDSPSPASTWSCTNS 219 >gi|30039710 pancreas specific transcription factor, 1a [Homo sapiens] Length = 328 Score = 59.3 bits (142), Expect = 3e-09 Identities = 52/141 (36%), Positives = 64/141 (45%), Gaps = 19/141 (13%) Query: 22 AAAGLAYGAAREPEAARGYG----TPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFE 77 A A + G EP+ G G T P G P +P A +G Sbjct: 80 ALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAA------VLS 133 Query: 78 QRRRRRG-PGSAADGRRRPREQRS------LRLSINARERRRMHDLNDALDGLRAVIPYA 130 R RG G+AA RR R RS LR + N RERRRM +NDA +GLR+ IP Sbjct: 134 PGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTL 193 Query: 131 HSPSVRKLSKIATLLLAKNYI 151 P ++LSK+ TL LA YI Sbjct: 194 --PYEKRLSKVDTLRLAIGYI 212 >gi|226498192 atonal homolog 8 [Homo sapiens] Length = 321 Score = 55.8 bits (133), Expect = 3e-08 Identities = 45/129 (34%), Positives = 64/129 (49%), Gaps = 23/129 (17%) Query: 50 PAAPAPRAPAQAAESS---------GEQS---------GDEDDAFEQRRRRRGPGSAADG 91 PA AP AP ES+ GE S + D+ R+R G +AA Sbjct: 163 PAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASS 222 Query: 92 RRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIP-YAHSPSVRKLSKIATLLLAKNY 150 + +Q + RL NARER R+H ++ A + LR +P Y++ +KLSK+A L +A NY Sbjct: 223 EIKALQQ-TRRLLANARERTRVHTISAAFEALRKQVPCYSYG---QKLSKLAILRIACNY 278 Query: 151 ILMQAQALD 159 IL A+ D Sbjct: 279 ILSLARLAD 287 >gi|23097242 nephew of atonal 3 [Homo sapiens] Length = 166 Score = 53.1 bits (126), Expect = 2e-07 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 13/117 (11%) Query: 55 PRAPAQAAESSGEQSG---DEDDAFEQRRRRRGPGSAADGRRRPREQRSL----RLSINA 107 PR A+ E E+ D+ D E+ RG G + GR P+ +R + R + N Sbjct: 51 PRRMARFEEGDPEEEECEVDQGDGEEEEEEERGRGVSLLGR--PKRKRVITYAQRQAANI 108 Query: 108 RERRRMHDLNDALDGLRAVIP-YAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR 163 RER+RM +LN+A D LR +P +A+ ++LS+I TL LA YI + L+ + Sbjct: 109 RERKRMFNLNEAFDQLRRKVPTFAYE---KRLSRIETLRLAIVYISFMTELLESCEK 162 >gi|4885075 atonal homolog 1 [Homo sapiens] Length = 354 Score = 52.8 bits (125), Expect = 2e-07 Identities = 34/71 (47%), Positives = 44/71 (61%), Gaps = 6/71 (8%) Query: 81 RRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140 R+R P S ++ Q+ RL+ NARERRRMH LN A D LR VIP ++ +KLSK Sbjct: 144 RQRAPSS----KQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNND--KKLSK 197 Query: 141 IATLLLAKNYI 151 TL +A+ YI Sbjct: 198 YETLQMAQIYI 208 >gi|4507741 twist [Homo sapiens] Length = 202 Score = 52.4 bits (124), Expect = 3e-07 Identities = 47/138 (34%), Positives = 58/138 (42%), Gaps = 21/138 (15%) Query: 29 GAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSA 88 G P A G G G GD P +PA + + G G G G + Sbjct: 47 GGGAGPGGAAGGGVGG--GDEPGSPAQGKRGKKSAGCGGGGG-----------AGGGGGS 93 Query: 89 ADGRRRPREQRSL---RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLL 145 + G P+ L R+ N RER+R LN+A LR +IP S KLSKI TL Sbjct: 94 SSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD---KLSKIQTLK 150 Query: 146 LAKNYI--LMQAQALDEM 161 LA YI L Q DE+ Sbjct: 151 LAARYIDFLYQVLQSDEL 168 >gi|148922889 scleraxis homolog B [Homo sapiens] Length = 201 Score = 52.0 bits (123), Expect = 4e-07 Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 16/108 (14%) Query: 57 APAQAAESSGEQSGDEDD----------AFEQRRRRRG---PGSAADGRRRPREQRSLRL 103 +P E G S D+ + RRR G G G R RE R R Sbjct: 20 SPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQ-RH 78 Query: 104 SINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151 + NARER R + +N A LR +IP P+ RKLSKI TL LA +YI Sbjct: 79 TANARERDRTNSVNTAFTALRTLIP--TEPADRKLSKIETLRLASSYI 124 >gi|186972126 scleraxis homolog A [Homo sapiens] Length = 201 Score = 52.0 bits (123), Expect = 4e-07 Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 16/108 (14%) Query: 57 APAQAAESSGEQSGDEDD----------AFEQRRRRRG---PGSAADGRRRPREQRSLRL 103 +P E G S D+ + RRR G G G R RE R R Sbjct: 20 SPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQ-RH 78 Query: 104 SINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151 + NARER R + +N A LR +IP P+ RKLSKI TL LA +YI Sbjct: 79 TANARERDRTNSVNTAFTALRTLIP--TEPADRKLSKIETLRLASSYI 124 >gi|17981708 twist homolog 2 [Homo sapiens] Length = 160 Score = 50.8 bits (120), Expect = 9e-07 Identities = 44/124 (35%), Positives = 57/124 (45%), Gaps = 20/124 (16%) Query: 54 APRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRP--------------REQR 99 +P +P + +S E+ + F R+RR S+ DG P E + Sbjct: 7 SPVSPVDSLGTSEEELERQPKRFG-RKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQ 65 Query: 100 SLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI--LMQAQA 157 S R+ N RER+R LN+A LR +IP S KLSKI TL LA YI L Q Sbjct: 66 SQRILANVRERQRTQSLNEAFAALRKIIPTLPSD---KLSKIQTLKLAARYIDFLYQVLQ 122 Query: 158 LDEM 161 DEM Sbjct: 123 SDEM 126 >gi|21553337 atonal homolog 7 [Homo sapiens] Length = 152 Score = 50.4 bits (119), Expect = 1e-06 Identities = 34/76 (44%), Positives = 42/76 (55%), Gaps = 4/76 (5%) Query: 88 AADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLA 147 A GR +R RL+ NARERRRM LN A D LR V+P +KLSK TL +A Sbjct: 30 AGAGRLESAARR--RLAANARERRRMQGLNTAFDRLRRVVPQWGQD--KKLSKYETLQMA 85 Query: 148 KNYILMQAQALDEMRR 163 +YI+ + L E R Sbjct: 86 LSYIMALTRILAEAER 101 >gi|48255909 basic helix-loop-helix transcription factor 15 [Homo sapiens] Length = 199 Score = 50.1 bits (118), Expect = 2e-06 Identities = 43/110 (39%), Positives = 50/110 (45%), Gaps = 18/110 (16%) Query: 64 SSGEQSGDEDDAFEQ--------RRRRRGPGSAADGRRR-------PREQRSLRLSINAR 108 S E++ E DA +Q RRGPG GRR P R + NAR Sbjct: 22 SEDEENRSESDASDQSFGCCEGPEAARRGPGPGG-GRRAGGGGGAGPVVVVRQRQAANAR 80 Query: 109 ERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 158 ER R +N A LR +IP P RKLSKI TL LA +YI A L Sbjct: 81 ERDRTQSVNTAFTALRTLIP--TEPVDRKLSKIETLRLASSYIAHLANVL 128 >gi|116805332 musculin [Homo sapiens] Length = 206 Score = 49.7 bits (117), Expect = 2e-06 Identities = 42/131 (32%), Positives = 62/131 (47%), Gaps = 21/131 (16%) Query: 51 AAPAPRAPAQAAESSGEQ-------SGDEDDAFEQRRRRRGPG----SAADGRRRPRE-- 97 A+P+ + A+ + GE+ +G + +R R G G SA G ++P Sbjct: 39 ASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAK 98 Query: 98 ------QRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151 ++S R + NARER RM L+ A L+ +P+ P KLSK+ TL LA +YI Sbjct: 99 GSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWV--PPDTKLSKLDTLRLASSYI 156 Query: 152 LMQAQALDEMR 162 Q L E R Sbjct: 157 AHLRQLLQEDR 167 >gi|239756681 PREDICTED: basic helix-loop-helix family, member a9 [Homo sapiens] Length = 203 Score = 46.2 bits (108), Expect = 2e-05 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%) Query: 83 RGPGSAADGRRRPREQRSL--RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140 RG GRRR R RS R++ N RER+R+ D N+A + LR + H ++LSK Sbjct: 46 RGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSK 103 Query: 141 IATL------LLAKNYILMQAQA-LDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCP 193 IATL + A + +L + A L +G A+P P G + P Sbjct: 104 IATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARP 163 Query: 194 FSAGAALGPCPDKCAA 209 +A ++ P +CA+ Sbjct: 164 DAARPSV-PSAPRCAS 178 >gi|239751178 PREDICTED: basic helix-loop-helix family, member a9 [Homo sapiens] Length = 235 Score = 46.2 bits (108), Expect = 2e-05 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%) Query: 83 RGPGSAADGRRRPREQRSL--RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140 RG GRRR R RS R++ N RER+R+ D N+A + LR + H ++LSK Sbjct: 46 RGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSK 103 Query: 141 IATL------LLAKNYILMQAQA-LDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCP 193 IATL + A + +L + A L +G A+P P G + P Sbjct: 104 IATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARP 163 Query: 194 FSAGAALGPCPDKCAA 209 +A ++ P +CA+ Sbjct: 164 DAARPSV-PSAPRCAS 178 >gi|239745666 PREDICTED: basic helix-loop-helix family, member a9 [Homo sapiens] Length = 235 Score = 46.2 bits (108), Expect = 2e-05 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%) Query: 83 RGPGSAADGRRRPREQRSL--RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140 RG GRRR R RS R++ N RER+R+ D N+A + LR + H ++LSK Sbjct: 46 RGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSK 103 Query: 141 IATL------LLAKNYILMQAQA-LDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCP 193 IATL + A + +L + A L +G A+P P G + P Sbjct: 104 IATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARP 163 Query: 194 FSAGAALGPCPDKCAA 209 +A ++ P +CA+ Sbjct: 164 DAARPSV-PSAPRCAS 178 >gi|38202237 transcription factor 21 [Homo sapiens] Length = 179 Score = 45.4 bits (106), Expect = 4e-05 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 20/126 (15%) Query: 65 SGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSL-----------RLSINARERRRM 113 + +S +E E ++G G R+ P ++ L R + NARER RM Sbjct: 33 TSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARM 92 Query: 114 HDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQG 173 L+ A L+ +P+ P KLSK+ TL LA +YI +R+++A G Sbjct: 93 RVLSKAFSRLKTTLPWV--PPDTKLSKLDTLRLASSYIA-------HLRQILANDKYENG 143 Query: 174 LAAPVN 179 PVN Sbjct: 144 YIHPVN 149 >gi|38202239 transcription factor 21 [Homo sapiens] Length = 179 Score = 45.4 bits (106), Expect = 4e-05 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 20/126 (15%) Query: 65 SGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSL-----------RLSINARERRRM 113 + +S +E E ++G G R+ P ++ L R + NARER RM Sbjct: 33 TSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARM 92 Query: 114 HDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQG 173 L+ A L+ +P+ P KLSK+ TL LA +YI +R+++A G Sbjct: 93 RVLSKAFSRLKTTLPWV--PPDTKLSKLDTLRLASSYIA-------HLRQILANDKYENG 143 Query: 174 LAAPVN 179 PVN Sbjct: 144 YIHPVN 149 >gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo sapiens] Length = 217 Score = 44.3 bits (103), Expect = 9e-05 Identities = 33/78 (42%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Query: 85 PGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATL 144 PG+ G PR + R + N +ERRR +N A LR IP + P+ KLSKI TL Sbjct: 85 PGAGPPGLGGPRPVKR-RGTANRKERRRTQSINSAFAELRECIP--NVPADTKLSKIKTL 141 Query: 145 LLAKNYI--LMQAQALDE 160 LA +YI LM A D+ Sbjct: 142 RLATSYIAYLMDLLAKDD 159 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,693,246 Number of Sequences: 37866 Number of extensions: 511263 Number of successful extensions: 5485 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 169 Number of HSP's successfully gapped in prelim test: 348 Number of HSP's that attempted gapping in prelim test: 4748 Number of HSP's gapped (non-prelim): 987 length of query: 225 length of database: 18,247,518 effective HSP length: 99 effective length of query: 126 effective length of database: 14,498,784 effective search space: 1826846784 effective search space used: 1826846784 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.