Search of human proteins with 57529222

Search of human proteins with 57529222

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57529222 basic helix-loop-helix domain containing, class B,
4 [Homo sapiens]
         (225 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57529222 basic helix-loop-helix domain containing, class B, 4...   452   e-127
gi|22748877 basic helix-loop-helix domain containing, class B, 5...   177   5e-45
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo...   105   2e-23
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]     102   2e-22
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]     84   7e-17
gi|98986461 neurogenic differentiation 2 [Homo sapiens]                78   7e-15
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    74   8e-14
gi|27475985 neurogenic differentiation 6 [Homo sapiens]                72   5e-13
gi|38455396 neurogenin 1 [Homo sapiens]                                70   1e-12
gi|153792190 neurogenic differentiation 4 [Homo sapiens]               70   2e-12
gi|121114306 neurogenic differentiation 1 [Homo sapiens]               69   2e-12
gi|68989258 neurogenin 3 [Homo sapiens]                                61   7e-10
gi|31077092 neurogenin 2 [Homo sapiens]                                60   2e-09
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    59   3e-09
gi|226498192 atonal homolog 8 [Homo sapiens]                           56   3e-08
gi|23097242 nephew of atonal 3 [Homo sapiens]                          53   2e-07
gi|4885075 atonal homolog 1 [Homo sapiens]                             53   2e-07
gi|4507741 twist [Homo sapiens]                                        52   3e-07
gi|148922889 scleraxis homolog B [Homo sapiens]                        52   4e-07
gi|186972126 scleraxis homolog A [Homo sapiens]                        52   4e-07
gi|17981708 twist homolog 2 [Homo sapiens]                             51   9e-07
gi|21553337 atonal homolog 7 [Homo sapiens]                            50   1e-06
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    50   2e-06
gi|116805332 musculin [Homo sapiens]                                   50   2e-06
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9...    46   2e-05
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9...    46   2e-05
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9...    46   2e-05
gi|38202237 transcription factor 21 [Homo sapiens]                     45   4e-05
gi|38202239 transcription factor 21 [Homo sapiens]                     45   4e-05
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    44   9e-05

>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score =  452 bits (1162), Expect = e-127
 Identities = 225/225 (100%), Positives = 225/225 (100%)

Query: 1   MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQ 60
           MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQ
Sbjct: 1   MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQ 60

Query: 61  AAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDAL 120
           AAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDAL
Sbjct: 61  AAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDAL 120

Query: 121 DGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNA 180
           DGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNA
Sbjct: 121 DGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNA 180

Query: 181 APLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP 225
           APLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP
Sbjct: 181 APLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP 225


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score =  177 bits (450), Expect = 5e-45
 Identities = 115/226 (50%), Positives = 133/226 (58%), Gaps = 38/226 (16%)

Query: 18  GYAAAAAGLA----YGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDED 73
           G A AA G +    +G A  P    G G  G GG    +            SG  SG   
Sbjct: 176 GGAKAAEGCSNAHLHGGASVPPGGLGGG--GGGGSSSGSSG------GGGGSGSGSGGSS 227

Query: 74  DAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSP 133
                        S++   ++ +EQ++LRL+INARERRRMHDLNDALD LRAVIPYAHSP
Sbjct: 228 S------------SSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSP 275

Query: 134 SVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGL---------AAPVNAAPLT 184
           SVRKLSKIATLLLAKNYILMQAQAL+EMRRLVA+LNQGQ +         AA   AA L 
Sbjct: 276 SVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALH 335

Query: 185 P----FGQATVCPFSAG-AALGPCPDKCAAFSGTPSALCKHCHEKP 225
           P    + QA   PFSAG      CP+KCA F+   S+LCK C EKP
Sbjct: 336 PALGAYEQAAGYPFSAGLPPAASCPEKCALFNSVSSSLCKQCTEKP 381


>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
           sapiens]
          Length = 323

 Score =  105 bits (263), Expect = 2e-23
 Identities = 60/107 (56%), Positives = 73/107 (68%), Gaps = 4/107 (3%)

Query: 97  EQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQ 156
           E + LRL IN+RER+RMHDLN A+DGLR V+PYAH PSVRKLSKIATLLLA+NYILM   
Sbjct: 105 ELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTN 164

Query: 157 ALDEMRRLVAFLNQGQGLAAPVNA----APLTPFGQATVCPFSAGAA 199
           +L+EM+RLV+ +  G       +A    A   P   AT  P +A  A
Sbjct: 165 SLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHA 211


>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
          Length = 272

 Score =  102 bits (255), Expect = 2e-22
 Identities = 51/76 (67%), Positives = 62/76 (81%)

Query: 96  REQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQA 155
           ++ + LRL IN RER+RMHDLN A+DGLR V+PYAH PSVRKLSKIATLLLA+NYILM  
Sbjct: 79  QDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLT 138

Query: 156 QALDEMRRLVAFLNQG 171
            +L+EM+RLV  +  G
Sbjct: 139 SSLEEMKRLVGEIYGG 154


>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
          Length = 271

 Score = 84.3 bits (207), Expect = 7e-17
 Identities = 71/163 (43%), Positives = 86/163 (52%), Gaps = 28/163 (17%)

Query: 55  PRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAAD--GRRRP----REQRSLRLSINAR 108
           P+A  +  E+  E  G             GPGS A   G  RP     +Q+ LR  IN+R
Sbjct: 66  PKAAREKPEAPAEPPGP------------GPGSGAHPGGSARPDAKEEQQQQLRRKINSR 113

Query: 109 ERRRMHDLNDALDGLRAVI-PY--AHSPSV--RKLSKIATLLLAKNYILMQAQALDEMRR 163
           ER+RM DLN A+D LR VI PY  AH      RKLSKIATLLLA+NYIL+   +L E+RR
Sbjct: 114 ERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRR 173

Query: 164 LVAFLNQGQGLAAP-VNAAPLTPFGQATVCPFSAGAALGPCPD 205
               L +G G AAP +  A L     A      A  A+GP PD
Sbjct: 174 A---LGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGP-PD 212


>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
          Length = 382

 Score = 77.8 bits (190), Expect = 7e-15
 Identities = 59/158 (37%), Positives = 78/158 (49%), Gaps = 25/158 (15%)

Query: 43  PGPGGDLPAAPAPRAPAQAAESS----------GEQSGDE----------DDAFEQRRRR 82
           PGPG   PA  A   P +  E +          GE  G+E          D+A  +R ++
Sbjct: 44  PGPGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKK 103

Query: 83  RGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIA 142
           RGP      + R    +  R   NARER RMHDLN ALD LR V+P       +KLSKI 
Sbjct: 104 RGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPC--YSKTQKLSKIE 161

Query: 143 TLLLAKNYILMQAQALDEMRR--LVAFLNQ-GQGLAAP 177
           TL LAKNYI   ++ L   +R  LV+++    +GL+ P
Sbjct: 162 TLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQP 199


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 58/120 (48%), Positives = 67/120 (55%), Gaps = 10/120 (8%)

Query: 32  REPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADG 91
           ++ EA  G GTP   G LP  P P  PA+   S   ++       E RRRR GP S   G
Sbjct: 15  QDTEATPGEGTPD--GSLPN-PGPE-PAKGLRSRPARAAARAPG-EGRRRRPGP-SGPGG 68

Query: 92  RRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151
           RR    QR  RL  N RER+RMH LN+A   LR VIP  H  + +KLSKI TL LAKNYI
Sbjct: 69  RRDSSIQR--RLESNERERQRMHKLNNAFQALREVIP--HVRADKKLSKIETLTLAKNYI 124


>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
          Length = 337

 Score = 71.6 bits (174), Expect = 5e-13
 Identities = 51/125 (40%), Positives = 66/125 (52%), Gaps = 5/125 (4%)

Query: 56  RAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHD 115
           RAP +  E   E+   E++      RRRG       + R    +  R   NARER RMH 
Sbjct: 50  RAPGEETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHG 109

Query: 116 LNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR--LVAFL-NQGQ 172
           LNDALD LR V+P       +KLSKI TL LAKNYI   ++ L   +R  L+ F+ N  +
Sbjct: 110 LNDALDNLRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCK 167

Query: 173 GLAAP 177
           GL+ P
Sbjct: 168 GLSQP 172


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 51/116 (43%), Positives = 62/116 (53%), Gaps = 18/116 (15%)

Query: 50  PAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQ-------RSLR 102
           P APA R     + +S E  G +DD  E+RRRR        GR R R +       RS R
Sbjct: 44  PPAPARRGAPNISRAS-EVPGAQDDEQERRRRR--------GRTRVRSEALLHSLRRSRR 94

Query: 103 LSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 158
           +  N RER RMH+LN ALD LR+V+P    P   KL+KI TL  A NYI   A+ L
Sbjct: 95  VKANDRERNRMHNLNAALDALRSVLP--SFPDDTKLTKIETLRFAYNYIWALAETL 148


>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
          Length = 331

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 42/97 (43%), Positives = 58/97 (59%), Gaps = 4/97 (4%)

Query: 63  ESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDG 122
           +S  E+  +E+D   ++ +RRGP      + R    R+ R+  NARER RMH LNDALD 
Sbjct: 52  DSIEEEEEEEEDG--EKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDN 109

Query: 123 LRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALD 159
           LR V+P       +KLSKI TL LA+NYI   ++ L+
Sbjct: 110 LRRVMPC--YSKTQKLSKIETLRLARNYIWALSEVLE 144


>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
          Length = 356

 Score = 69.3 bits (168), Expect = 2e-12
 Identities = 47/118 (39%), Positives = 66/118 (55%), Gaps = 5/118 (4%)

Query: 63  ESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDG 122
           E   E+  +E++  +Q+ +RRGP      + R    +  R+  NARER RMH LN ALD 
Sbjct: 64  EDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDN 123

Query: 123 LRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR--LVAFLNQ-GQGLAAP 177
           LR V+P       +KLSKI TL LAKNYI   ++ L   +   LV+F+    +GL+ P
Sbjct: 124 LRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQP 179


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 16/113 (14%)

Query: 54  APRAPAQAAESSGE-QSGDEDDAFEQRRRRRGPGSAADGRRRPR-------EQRSLRLSI 105
           AP +P +   +  E + G    A  + R RRG      GR RP+       ++RS R   
Sbjct: 35  APPSPTRTRGNCAEAEEGGCRGAPRKLRARRG------GRSRPKSELALSKQRRSRRKKA 88

Query: 106 NARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 158
           N RER RMH+LN ALD LR V+P    P   KL+KI TL  A NYI    Q L
Sbjct: 89  NDRERNRMHNLNSALDALRGVLP--TFPDDAKLTKIETLRFAHNYIWALTQTL 139


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 67/209 (32%), Positives = 83/209 (39%), Gaps = 56/209 (26%)

Query: 51  AAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGP-----------------------GS 87
           A+PA  A    + S+ E+  +E  A    RR+RG                        G 
Sbjct: 23  ASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGL 82

Query: 88  AADGRRRPREQRSL-----------------RLSINARERRRMHDLNDALDGLRAVIPYA 130
             D +RRP   R++                 RL  N RER RMH+LN ALD LR V+P  
Sbjct: 83  VHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP-- 140

Query: 131 HSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQAT 190
             P   KL+KI TL  A NYI     AL E  RL      G G        P   F +A 
Sbjct: 141 TFPEDAKLTKIETLRFAHNYI----WALTETLRLADHCGGGGG------GLPGALFSEAV 190

Query: 191 -VCPFSAGAAL---GPCPDKCAAFSGTPS 215
            + P  A AAL   G  P   + +S T S
Sbjct: 191 LLSPGGASAALSSSGDSPSPASTWSCTNS 219


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 52/141 (36%), Positives = 64/141 (45%), Gaps = 19/141 (13%)

Query: 22  AAAGLAYGAAREPEAARGYG----TPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFE 77
           A A  + G   EP+   G G    T  P G  P +P       A   +G           
Sbjct: 80  ALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAA------VLS 133

Query: 78  QRRRRRG-PGSAADGRRRPREQRS------LRLSINARERRRMHDLNDALDGLRAVIPYA 130
              R RG  G+AA   RR R  RS      LR + N RERRRM  +NDA +GLR+ IP  
Sbjct: 134 PGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTL 193

Query: 131 HSPSVRKLSKIATLLLAKNYI 151
             P  ++LSK+ TL LA  YI
Sbjct: 194 --PYEKRLSKVDTLRLAIGYI 212


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 45/129 (34%), Positives = 64/129 (49%), Gaps = 23/129 (17%)

Query: 50  PAAPAPRAPAQAAESS---------GEQS---------GDEDDAFEQRRRRRGPGSAADG 91
           PA  AP AP    ES+         GE S          +  D+    R+R G  +AA  
Sbjct: 163 PAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASS 222

Query: 92  RRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIP-YAHSPSVRKLSKIATLLLAKNY 150
             +  +Q + RL  NARER R+H ++ A + LR  +P Y++    +KLSK+A L +A NY
Sbjct: 223 EIKALQQ-TRRLLANARERTRVHTISAAFEALRKQVPCYSYG---QKLSKLAILRIACNY 278

Query: 151 ILMQAQALD 159
           IL  A+  D
Sbjct: 279 ILSLARLAD 287


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 13/117 (11%)

Query: 55  PRAPAQAAESSGEQSG---DEDDAFEQRRRRRGPGSAADGRRRPREQRSL----RLSINA 107
           PR  A+  E   E+     D+ D  E+    RG G +  GR  P+ +R +    R + N 
Sbjct: 51  PRRMARFEEGDPEEEECEVDQGDGEEEEEEERGRGVSLLGR--PKRKRVITYAQRQAANI 108

Query: 108 RERRRMHDLNDALDGLRAVIP-YAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR 163
           RER+RM +LN+A D LR  +P +A+    ++LS+I TL LA  YI    + L+   +
Sbjct: 109 RERKRMFNLNEAFDQLRRKVPTFAYE---KRLSRIETLRLAIVYISFMTELLESCEK 162


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 34/71 (47%), Positives = 44/71 (61%), Gaps = 6/71 (8%)

Query: 81  RRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140
           R+R P S    ++    Q+  RL+ NARERRRMH LN A D LR VIP  ++   +KLSK
Sbjct: 144 RQRAPSS----KQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNND--KKLSK 197

Query: 141 IATLLLAKNYI 151
             TL +A+ YI
Sbjct: 198 YETLQMAQIYI 208


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 47/138 (34%), Positives = 58/138 (42%), Gaps = 21/138 (15%)

Query: 29  GAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSA 88
           G    P  A G G  G  GD P +PA     + +   G   G             G G +
Sbjct: 47  GGGAGPGGAAGGGVGG--GDEPGSPAQGKRGKKSAGCGGGGG-----------AGGGGGS 93

Query: 89  ADGRRRPREQRSL---RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLL 145
           + G   P+    L   R+  N RER+R   LN+A   LR +IP   S    KLSKI TL 
Sbjct: 94  SSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD---KLSKIQTLK 150

Query: 146 LAKNYI--LMQAQALDEM 161
           LA  YI  L Q    DE+
Sbjct: 151 LAARYIDFLYQVLQSDEL 168


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 16/108 (14%)

Query: 57  APAQAAESSGEQSGDEDD----------AFEQRRRRRG---PGSAADGRRRPREQRSLRL 103
           +P    E  G  S   D+            +  RRR G    G    G R  RE R  R 
Sbjct: 20  SPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQ-RH 78

Query: 104 SINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151
           + NARER R + +N A   LR +IP    P+ RKLSKI TL LA +YI
Sbjct: 79  TANARERDRTNSVNTAFTALRTLIP--TEPADRKLSKIETLRLASSYI 124


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 16/108 (14%)

Query: 57  APAQAAESSGEQSGDEDD----------AFEQRRRRRG---PGSAADGRRRPREQRSLRL 103
           +P    E  G  S   D+            +  RRR G    G    G R  RE R  R 
Sbjct: 20  SPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQ-RH 78

Query: 104 SINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151
           + NARER R + +N A   LR +IP    P+ RKLSKI TL LA +YI
Sbjct: 79  TANARERDRTNSVNTAFTALRTLIP--TEPADRKLSKIETLRLASSYI 124


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 44/124 (35%), Positives = 57/124 (45%), Gaps = 20/124 (16%)

Query: 54  APRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRP--------------REQR 99
           +P +P  +  +S E+   +   F  R+RR    S+ DG   P               E +
Sbjct: 7   SPVSPVDSLGTSEEELERQPKRFG-RKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQ 65

Query: 100 SLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI--LMQAQA 157
           S R+  N RER+R   LN+A   LR +IP   S    KLSKI TL LA  YI  L Q   
Sbjct: 66  SQRILANVRERQRTQSLNEAFAALRKIIPTLPSD---KLSKIQTLKLAARYIDFLYQVLQ 122

Query: 158 LDEM 161
            DEM
Sbjct: 123 SDEM 126


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 34/76 (44%), Positives = 42/76 (55%), Gaps = 4/76 (5%)

Query: 88  AADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLA 147
           A  GR     +R  RL+ NARERRRM  LN A D LR V+P       +KLSK  TL +A
Sbjct: 30  AGAGRLESAARR--RLAANARERRRMQGLNTAFDRLRRVVPQWGQD--KKLSKYETLQMA 85

Query: 148 KNYILMQAQALDEMRR 163
            +YI+   + L E  R
Sbjct: 86  LSYIMALTRILAEAER 101


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 43/110 (39%), Positives = 50/110 (45%), Gaps = 18/110 (16%)

Query: 64  SSGEQSGDEDDAFEQ--------RRRRRGPGSAADGRRR-------PREQRSLRLSINAR 108
           S  E++  E DA +Q           RRGPG    GRR        P      R + NAR
Sbjct: 22  SEDEENRSESDASDQSFGCCEGPEAARRGPGPGG-GRRAGGGGGAGPVVVVRQRQAANAR 80

Query: 109 ERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 158
           ER R   +N A   LR +IP    P  RKLSKI TL LA +YI   A  L
Sbjct: 81  ERDRTQSVNTAFTALRTLIP--TEPVDRKLSKIETLRLASSYIAHLANVL 128


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 42/131 (32%), Positives = 62/131 (47%), Gaps = 21/131 (16%)

Query: 51  AAPAPRAPAQAAESSGEQ-------SGDEDDAFEQRRRRRGPG----SAADGRRRPRE-- 97
           A+P+  + A+  +  GE+       +G  +    +R R  G G    SA  G ++P    
Sbjct: 39  ASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAK 98

Query: 98  ------QRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYI 151
                 ++S R + NARER RM  L+ A   L+  +P+   P   KLSK+ TL LA +YI
Sbjct: 99  GSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWV--PPDTKLSKLDTLRLASSYI 156

Query: 152 LMQAQALDEMR 162
               Q L E R
Sbjct: 157 AHLRQLLQEDR 167


>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 203

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%)

Query: 83  RGPGSAADGRRRPREQRSL--RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140
           RG      GRRR R  RS   R++ N RER+R+ D N+A + LR  +   H    ++LSK
Sbjct: 46  RGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSK 103

Query: 141 IATL------LLAKNYILMQAQA-LDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCP 193
           IATL      + A + +L  + A       L       +G      A+P  P G +   P
Sbjct: 104 IATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARP 163

Query: 194 FSAGAALGPCPDKCAA 209
            +A  ++ P   +CA+
Sbjct: 164 DAARPSV-PSAPRCAS 178


>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%)

Query: 83  RGPGSAADGRRRPREQRSL--RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140
           RG      GRRR R  RS   R++ N RER+R+ D N+A + LR  +   H    ++LSK
Sbjct: 46  RGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSK 103

Query: 141 IATL------LLAKNYILMQAQA-LDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCP 193
           IATL      + A + +L  + A       L       +G      A+P  P G +   P
Sbjct: 104 IATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARP 163

Query: 194 FSAGAALGPCPDKCAA 209
            +A  ++ P   +CA+
Sbjct: 164 DAARPSV-PSAPRCAS 178


>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 12/136 (8%)

Query: 83  RGPGSAADGRRRPREQRSL--RLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140
           RG      GRRR R  RS   R++ N RER+R+ D N+A + LR  +   H    ++LSK
Sbjct: 46  RGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRAL--RHDLGGKRLSK 103

Query: 141 IATL------LLAKNYILMQAQA-LDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCP 193
           IATL      + A + +L  + A       L       +G      A+P  P G +   P
Sbjct: 104 IATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARP 163

Query: 194 FSAGAALGPCPDKCAA 209
            +A  ++ P   +CA+
Sbjct: 164 DAARPSV-PSAPRCAS 178


>gi|38202237 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 20/126 (15%)

Query: 65  SGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSL-----------RLSINARERRRM 113
           +  +S +E    E    ++G G     R+ P ++  L           R + NARER RM
Sbjct: 33  TSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARM 92

Query: 114 HDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQG 173
             L+ A   L+  +P+   P   KLSK+ TL LA +YI         +R+++A      G
Sbjct: 93  RVLSKAFSRLKTTLPWV--PPDTKLSKLDTLRLASSYIA-------HLRQILANDKYENG 143

Query: 174 LAAPVN 179
              PVN
Sbjct: 144 YIHPVN 149


>gi|38202239 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 20/126 (15%)

Query: 65  SGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSL-----------RLSINARERRRM 113
           +  +S +E    E    ++G G     R+ P ++  L           R + NARER RM
Sbjct: 33  TSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARM 92

Query: 114 HDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQG 173
             L+ A   L+  +P+   P   KLSK+ TL LA +YI         +R+++A      G
Sbjct: 93  RVLSKAFSRLKTTLPWV--PPDTKLSKLDTLRLASSYIA-------HLRQILANDKYENG 143

Query: 174 LAAPVN 179
              PVN
Sbjct: 144 YIHPVN 149


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 33/78 (42%), Positives = 42/78 (53%), Gaps = 5/78 (6%)

Query: 85  PGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATL 144
           PG+   G   PR  +  R + N +ERRR   +N A   LR  IP  + P+  KLSKI TL
Sbjct: 85  PGAGPPGLGGPRPVKR-RGTANRKERRRTQSINSAFAELRECIP--NVPADTKLSKIKTL 141

Query: 145 LLAKNYI--LMQAQALDE 160
            LA +YI  LM   A D+
Sbjct: 142 RLATSYIAYLMDLLAKDD 159


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,693,246
Number of Sequences: 37866
Number of extensions: 511263
Number of successful extensions: 5485
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 348
Number of HSP's that attempted gapping in prelim test: 4748
Number of HSP's gapped (non-prelim): 987
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.