Guide to the Human Genome
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Search of human proteins with 5729947

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729947 neuromedin U [Homo sapiens]
         (174 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729947 neuromedin U [Homo sapiens]                                355   1e-98
gi|58743316 neuromedin S [Homo sapiens]                                61   6e-10
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          33   0.16 
gi|4504217 guanylate cyclase 2D, membrane (retina-specific) [Hom...    31   0.47 
gi|72534716 coiled-coil domain containing 90A [Homo sapiens]           29   1.8  
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]         29   2.3  
gi|239750490 PREDICTED: similar to hCG1820441 [Homo sapiens]           29   2.3  
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]      29   2.3  
gi|239749931 PREDICTED: FLJ43861 protein [Homo sapiens]                28   3.1  
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n...    28   4.0  
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]              28   4.0  
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]              28   4.0  
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]                28   5.2  
gi|11072101 rhomboid domain containing 3 [Homo sapiens]                28   5.2  
gi|47777319 hypothetical protein LOC55181 [Homo sapiens]               27   6.8  
gi|71061468 centromere protein E [Homo sapiens]                        27   6.8  
gi|7019563 testes-specific protease 50 [Homo sapiens]                  27   6.8  
gi|46559747 hypothetical protein LOC399947 [Homo sapiens]              27   6.8  
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu...    27   8.9  
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu...    27   8.9  
gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo sap...    27   8.9  
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2...    27   8.9  
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1...    27   8.9  

>gi|5729947 neuromedin U [Homo sapiens]
          Length = 174

 Score =  355 bits (910), Expect = 1e-98
 Identities = 174/174 (100%), Positives = 174/174 (100%)

Query: 1   MLRTESCRPRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWNEIDD 60
           MLRTESCRPRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWNEIDD
Sbjct: 1   MLRTESCRPRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWNEIDD 60

Query: 61  TCSSFLSIDSQPQASNALEELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLGKSNVV 120
           TCSSFLSIDSQPQASNALEELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLGKSNVV
Sbjct: 61  TCSSFLSIDSQPQASNALEELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLGKSNVV 120

Query: 121 SSVVHPLLQLVPHLHERRMKRFRVDEEFQSPFASQSRGYFLFRPRNGRRSAGFI 174
           SSVVHPLLQLVPHLHERRMKRFRVDEEFQSPFASQSRGYFLFRPRNGRRSAGFI
Sbjct: 121 SSVVHPLLQLVPHLHERRMKRFRVDEEFQSPFASQSRGYFLFRPRNGRRSAGFI 174


>gi|58743316 neuromedin S [Homo sapiens]
          Length = 153

 Score = 60.8 bits (146), Expect = 6e-10
 Identities = 41/101 (40%), Positives = 52/101 (51%), Gaps = 10/101 (9%)

Query: 78  LEELCFMIMGMLP-KPQEQDEKDNTKRFLFHYSKTQKLGKS-NVVSSVVHPLLQLVPHLH 135
           LE+L + +    P   Q +D +D  KRFLFHYS+TQ+           VHPL+ L   L 
Sbjct: 43  LEQLAYCLSQWAPLSRQPKDNQDIYKRFLFHYSRTQEATHPVKTGFPPVHPLMHLAAKLA 102

Query: 136 ERRMKRF--------RVDEEFQSPFASQSRGYFLFRPRNGR 168
            RRMKR          VD   +   A+  R +FLFRPRNGR
Sbjct: 103 NRRMKRILQRGSGTAAVDFTKKDHTATWGRPFFLFRPRNGR 143


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 32.7 bits (73), Expect = 0.16
 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 13/128 (10%)

Query: 16  VAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWN--EIDDTCSS--------F 65
           + A +  LLLLLLL  C  A  GA +   G   EQ L+L     +D+  SS         
Sbjct: 1   MGAPAASLLLLLLLFACCWAPGGANLSQDGYWQEQDLELGTLAPLDEAISSTVWSSPDML 60

Query: 66  LSIDSQPQASNALEELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLGKSNVVSSVVH 125
            S DSQP  S   +E       ++ K Q +D +D++ ++     +T   G+   +     
Sbjct: 61  ASQDSQPWTS---DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRI 117

Query: 126 PLLQLVPH 133
            L+   PH
Sbjct: 118 QLVTSTPH 125


>gi|4504217 guanylate cyclase 2D, membrane (retina-specific) [Homo
           sapiens]
          Length = 1103

 Score = 31.2 bits (69), Expect = 0.47
 Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 36  CRGAPILPQGLQPEQQLQLWNEIDDTCSSFLSIDSQPQASNALEELCFMIMGMLPKPQEQ 95
           CR AP     L PE+ +Q        C   +S+D  P     L + C+       +P+ +
Sbjct: 741 CRSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECILLMKQCW-----AEQPELR 795

Query: 96  DEKDNTKRFLFHYSKTQKLGKSNVVSSVVHPLLQLVPHLHE 136
              D+T     + +K +   K+N++ S++  L Q   +L +
Sbjct: 796 PSMDHTFDLFKNINKGR---KTNIIDSMLRMLEQYSSNLED 833


>gi|72534716 coiled-coil domain containing 90A [Homo sapiens]
          Length = 359

 Score = 29.3 bits (64), Expect = 1.8
 Identities = 16/23 (69%), Positives = 19/23 (82%), Gaps = 2/23 (8%)

Query: 8  RPRSPA--GQVAAASPLLLLLLL 28
          RPR+PA  G V+ ASPLLLLLL+
Sbjct: 53 RPRAPAARGGVSRASPLLLLLLV 75


>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
          Length = 206

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 16/62 (25%), Positives = 24/62 (38%)

Query: 12 PAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWNEIDDTCSSFLSIDSQ 71
          P     A  P +LL LL  W       AP  P G    +  + W  +     + L + +Q
Sbjct: 4  PGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPVAAQ 63

Query: 72 PQ 73
          P+
Sbjct: 64 PK 65


>gi|239750490 PREDICTED: similar to hCG1820441 [Homo sapiens]
          Length = 576

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 16/50 (32%), Positives = 22/50 (44%)

Query: 109 SKTQKLGKSNVVSSVVHPLLQLVPHLHERRMKRFRVDEEFQSPFASQSRG 158
           + T+ L    +  + V  L   V H+  R    FRV EE +S     SRG
Sbjct: 196 NNTKSLSDGMITMATVKVLQSYVCHMRNRNRLHFRVAEEMESEQQVHSRG 245


>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
          Length = 1159

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 7/44 (15%)

Query: 9  PRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQL 52
          PRSP  +     PLLLLLLLL  C  A R     P  L P  QL
Sbjct: 28 PRSPRSR-----PLLLLLLLLGACGAAGRSPE--PGRLGPHAQL 64


>gi|239749931 PREDICTED: FLJ43861 protein [Homo sapiens]
          Length = 642

 Score = 28.5 bits (62), Expect = 3.1
 Identities = 15/29 (51%), Positives = 17/29 (58%)

Query: 7  CRPRSPAGQVAAASPLLLLLLLLAWCAGA 35
          C PRSP G+ AAA+P        AW AGA
Sbjct: 25 CEPRSPPGRPAAAAPPPSSHCGQAWRAGA 53


>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
          netrin domain containing 1 precursor [Homo sapiens]
          Length = 548

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 13/77 (16%)

Query: 18 AASPLLLLLLLLAWCAGACRGAPILP-----QGLQPEQ-QLQLWNEIDDTCSSFLSIDSQ 71
          A  PLL LLLLL   +GA     +LP      G+ P Q    LW +   TC    S D  
Sbjct: 3  ALRPLLPLLLLLRLTSGA----GLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECSRD-- 56

Query: 72 PQASNALEELCFMIMGM 88
           Q   A E+ C  + G+
Sbjct: 57 -QDCAAAEKCCINVCGL 72


>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
          Length = 713

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 22 LLLLLLLLAWCAGACRGAPILP 43
          LL+  LLLAW AGA    P++P
Sbjct: 3  LLVAPLLLAWVAGATAAVPVVP 24


>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
          Length = 713

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 22 LLLLLLLLAWCAGACRGAPILP 43
          LL+  LLLAW AGA    P++P
Sbjct: 3  LLVAPLLLAWVAGATAAVPVVP 24


>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
          Length = 2778

 Score = 27.7 bits (60), Expect = 5.2
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 30  AWCAGACRGAPI--LPQGLQPEQQ-LQLWNEIDD--TCSSFLSIDSQPQASNALEELCFM 84
           +WC GAC+ AP    P G  P    L L   + D   C +F S  + P+    L   C  
Sbjct: 578 SWCQGACQAAPPPGTPLGACPAASCLGLGRLLGDCQACLAFSSPTAPPRGPGTL-GWCVH 636

Query: 85  IMGMLPKPQE 94
               LP+P++
Sbjct: 637 NESCLPRPEQ 646


>gi|11072101 rhomboid domain containing 3 [Homo sapiens]
          Length = 386

 Score = 27.7 bits (60), Expect = 5.2
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 10 RSPAGQVAAASPL----LLLLLLLAWCAGACRGAPILPQ 44
          R P GQ++ A PL    L+LL+   W  GA  G  + P+
Sbjct: 4  RGPHGQLSPALPLASSVLMLLMSTLWLVGAGPGLVLAPE 42


>gi|47777319 hypothetical protein LOC55181 [Homo sapiens]
          Length = 991

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 1/63 (1%)

Query: 57  EIDDTCSSFLSIDSQPQASNAL-EELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLG 115
           ++ + C  F S   Q     +L ++ C      LPK  E+ E D     L+H S+ +  G
Sbjct: 550 QLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTG 609

Query: 116 KSN 118
             N
Sbjct: 610 ACN 612


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 3/40 (7%)

Query: 42  LPQGLQPEQQLQLWNEIDDTCSSFLSIDSQPQASNALEEL 81
           L + LQ E+  QL ++I DT +  ++ID+Q Q  NALE L
Sbjct: 937 LQESLQIERD-QLKSDIHDTVN--MNIDTQEQLRNALESL 973


>gi|7019563 testes-specific protease 50 [Homo sapiens]
          Length = 385

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 19/46 (41%), Positives = 22/46 (47%)

Query: 8  RPRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQ 53
          RPR+ A   A A  LLLLLL  A C GA      L      +Q +Q
Sbjct: 13 RPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQ 58


>gi|46559747 hypothetical protein LOC399947 [Homo sapiens]
          Length = 197

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 4/41 (9%)

Query: 133 HLHERRMKR---FRVDEEFQSPFASQSRGYFLFRPRNGRRS 170
           H+H+RRMK+    R  EE++    S SRG     PR GR++
Sbjct: 83  HIHKRRMKKRKMQRAQEEYERDHCSGSRGGGGL-PRPGRQA 122


>gi|33598931 scavenger receptor class F, member 1 isoform 3
           precursor [Homo sapiens]
          Length = 569

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 11/64 (17%)

Query: 6   SCRPRSPAGQVAAAS----PLLLLLLLLAWCAGAC-------RGAPILPQGLQPEQQLQL 54
           SC+P S +   A  +    PLLLL L LA CA  C       +  P          +LQ+
Sbjct: 411 SCQPGSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQV 470

Query: 55  WNEI 58
           W  +
Sbjct: 471 WGTL 474


>gi|33598929 scavenger receptor class F, member 1 isoform 1
           precursor [Homo sapiens]
          Length = 830

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 11/64 (17%)

Query: 6   SCRPRSPAGQVAAAS----PLLLLLLLLAWCAGAC-------RGAPILPQGLQPEQQLQL 54
           SC+P S +   A  +    PLLLL L LA CA  C       +  P          +LQ+
Sbjct: 411 SCQPGSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQV 470

Query: 55  WNEI 58
           W  +
Sbjct: 471 WGTL 474


>gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo
           sapiens]
          Length = 328

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 13/37 (35%), Positives = 17/37 (45%)

Query: 8   RPRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQ 44
           RPR P G  AAA+ ++       +C   C G    PQ
Sbjct: 266 RPRGPPGGAAAAASVMAPRRSRCFCTSICGGRGARPQ 302


>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
           [Homo sapiens]
          Length = 659

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 10/69 (14%)

Query: 42  LPQGLQPEQQLQL---------WN-EIDDTCSSFLSIDSQPQASNALEELCFMIMGMLPK 91
           LP+GL P  Q +          W+ ++ D+ S  L  + QP+  N +E+     M  LP 
Sbjct: 355 LPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPV 414

Query: 92  PQEQDEKDN 100
           P +    D+
Sbjct: 415 PNQDVTSDD 423


>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
           [Homo sapiens]
          Length = 660

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 10/69 (14%)

Query: 42  LPQGLQPEQQLQL---------WN-EIDDTCSSFLSIDSQPQASNALEELCFMIMGMLPK 91
           LP+GL P  Q +          W+ ++ D+ S  L  + QP+  N +E+     M  LP 
Sbjct: 356 LPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPV 415

Query: 92  PQEQDEKDN 100
           P +    D+
Sbjct: 416 PNQDVTSDD 424


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,214,068
Number of Sequences: 37866
Number of extensions: 331089
Number of successful extensions: 1023
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1005
Number of HSP's gapped (non-prelim): 28
length of query: 174
length of database: 18,247,518
effective HSP length: 95
effective length of query: 79
effective length of database: 14,650,248
effective search space: 1157369592
effective search space used: 1157369592
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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