BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5729734 activator of S phase kinase [Homo sapiens] (674 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5729734 activator of S phase kinase [Homo sapiens] 1356 0.0 gi|22035682 DBF4 homolog B isoform 1 [Homo sapiens] 181 1e-45 gi|13376671 DBF4 homolog B isoform 2 [Homo sapiens] 78 2e-14 gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens] 50 7e-06 gi|38044112 restin isoform b [Homo sapiens] 45 2e-04 gi|4506751 restin isoform a [Homo sapiens] 45 2e-04 gi|148612801 KIAA1009 protein [Homo sapiens] 43 8e-04 gi|144226234 metastasis suppressor 1 [Homo sapiens] 41 0.003 gi|34878777 ring finger protein 20 [Homo sapiens] 40 0.009 gi|158187521 A-kinase anchor protein 5 [Homo sapiens] 39 0.020 gi|115648142 centrosomal protein 164kDa [Homo sapiens] 38 0.027 gi|71061468 centromere protein E [Homo sapiens] 38 0.027 gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 38 0.035 gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 38 0.035 gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 37 0.046 gi|9910266 kinesin family member 15 [Homo sapiens] 37 0.078 gi|110815815 centlein isoform 1 [Homo sapiens] 37 0.078 gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso... 35 0.23 gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso... 35 0.23 gi|4758650 kinesin family member 5C [Homo sapiens] 35 0.30 gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 35 0.30 gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 35 0.30 gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 35 0.30 gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 35 0.30 gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 35 0.30 gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 35 0.30 gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 35 0.30 gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 34 0.39 gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 34 0.39 gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 34 0.39 >gi|5729734 activator of S phase kinase [Homo sapiens] Length = 674 Score = 1356 bits (3510), Expect = 0.0 Identities = 674/674 (100%), Positives = 674/674 (100%) Query: 1 MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTI 60 MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTI Sbjct: 1 MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTI 60 Query: 61 SEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLGRISPVPSPESAYTAETTSPH 120 SEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLGRISPVPSPESAYTAETTSPH Sbjct: 61 SEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLGRISPVPSPESAYTAETTSPH 120 Query: 121 PSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIPSNSILSNALSWGVKILHIDDIRYYIE 180 PSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIPSNSILSNALSWGVKILHIDDIRYYIE Sbjct: 121 PSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIPSNSILSNALSWGVKILHIDDIRYYIE 180 Query: 181 QKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMP 240 QKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMP Sbjct: 181 QKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMP 240 Query: 241 FINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCL 300 FINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCL Sbjct: 241 FINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCL 300 Query: 301 QKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLSP 360 QKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLSP Sbjct: 301 QKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLSP 360 Query: 361 VSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPS 420 VSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPS Sbjct: 361 VSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPS 420 Query: 421 NELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVD 480 NELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVD Sbjct: 421 NELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVD 480 Query: 481 HYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHDSGLITINSSQ 540 HYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHDSGLITINSSQ Sbjct: 481 HYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHDSGLITINSSQ 540 Query: 541 EHLTVQAKAPFHTPPEEPNECDFKNMDSLPSGKIHRKVKIILGRNRKENLEPNAEFDKRT 600 EHLTVQAKAPFHTPPEEPNECDFKNMDSLPSGKIHRKVKIILGRNRKENLEPNAEFDKRT Sbjct: 541 EHLTVQAKAPFHTPPEEPNECDFKNMDSLPSGKIHRKVKIILGRNRKENLEPNAEFDKRT 600 Query: 601 EFITQEENRICSSPVQSLLDLFQTSEEKSEFLGFTSYTEKSGICNVLDIWEEENSDNLLT 660 EFITQEENRICSSPVQSLLDLFQTSEEKSEFLGFTSYTEKSGICNVLDIWEEENSDNLLT Sbjct: 601 EFITQEENRICSSPVQSLLDLFQTSEEKSEFLGFTSYTEKSGICNVLDIWEEENSDNLLT 660 Query: 661 AFFSSPSTSTFTGF 674 AFFSSPSTSTFTGF Sbjct: 661 AFFSSPSTSTFTGF 674 >gi|22035682 DBF4 homolog B isoform 1 [Homo sapiens] Length = 615 Score = 181 bits (460), Expect = 1e-45 Identities = 112/308 (36%), Positives = 173/308 (56%), Gaps = 20/308 (6%) Query: 45 PLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLGRI-- 102 P GK FYLDLP+ + L I+ LGG +E FLSK++SY++S+++E K A++ G+ Sbjct: 47 PFSGKSFYLDLPAGKNLQFLTGAIQQLGGVIEGFLSKEVSYIVSSRREVK-AESSGKSHR 105 Query: 103 ---SPVPSPESAYTAETTSPHPSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIP----- 154 SP PS T+ P SH S K D+V LSRGK L++KAI++ I Sbjct: 106 GCPSPSPSEVRVETSAMVDPKGSHPRPSRKPVDSVPLSRGKELLQKAIRNQGSISGGGSG 165 Query: 155 -SNSILSNALSWGVKILHIDDIRYYIEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTG 213 S+S+L+NA SWGV+ILH+D++ +++Q +KK + G + ++ + Sbjct: 166 GSSSLLTNARSWGVRILHVDEMMMHVQQLSLASLCVKKQQPK-KPEGTCPAAESRTRKVA 224 Query: 214 RLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQT 273 RLK PF+K+ED S+ +RPF+ Q + P I++ K SPF+ T R Sbjct: 225 RLKAPFLKIEDESRKFRPFHHQFKSFPEISFLGPKDASPFEAPTTLGSMHHT----RESK 280 Query: 274 DGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFA-QSNQYQVVDDIVS 332 DG+ ++ ++KKGYCECC + +E+L HL S QHR+FA +++ Y VD I++ Sbjct: 281 DGEPSPRSAAHTM--PRRKKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIA 338 Query: 333 KLVFDFVE 340 +L F + Sbjct: 339 QLSHSFAD 346 >gi|13376671 DBF4 homolog B isoform 2 [Homo sapiens] Length = 170 Score = 78.2 bits (191), Expect = 2e-14 Identities = 51/127 (40%), Positives = 71/127 (55%), Gaps = 18/127 (14%) Query: 45 PLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLGRI-- 102 P GK FYLDLP+ + L I+ LGG +E FLSK++SY++S+++E K A++ G+ Sbjct: 47 PFSGKSFYLDLPAGKNLQFLTGAIQQLGGVIEGFLSKEVSYIVSSRREVK-AESSGKSHR 105 Query: 103 ---SPVPSPESAYTAETTSPHPSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIPSNSIL 159 SP PS T+ P SH S K D+V LSRGK L++KAI+ Sbjct: 106 GCPSPSPSEVRVETSAMVDPKGSHPRPSRKPVDSVPLSRGKELLQKAIR----------- 154 Query: 160 SNALSWG 166 N +SWG Sbjct: 155 -NQVSWG 160 >gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens] Length = 2354 Score = 50.1 bits (118), Expect = 7e-06 Identities = 55/238 (23%), Positives = 108/238 (45%), Gaps = 35/238 (14%) Query: 290 KKKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQYQV-VDDIVSKLVFDFVEYEKDTPKK 348 +K++GYC C +Y +LE HL S QHR+ + ++ Q+ ++ + + D +++ Sbjct: 2 QKRQGYCSYCRVQYNNLEQHLFSAQHRSLTRQSRRQICTSSLMERFLQDVLQHHP----- 56 Query: 349 KRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKK 408 + S S + + E V L ++ +ED+ V++++ TE++ Sbjct: 57 ---YHCQESSSTQDETHVNTGSSSEVVHLDDAFSEEEEEDEDKVEDED-------ATEER 106 Query: 409 LLFISEPI------PHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQL-PLHKNKQEC- 460 +SEPI PH S E +++S + S++ E +Q + + + ++C Sbjct: 107 PSEVSEPIEELHSRPHKSQE---GTQEVSVRPSVIQKLEKGQQQPLEFVHKIGASVRKCN 163 Query: 461 ILDISEHTLSENDLEELRVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDL 518 ++DI + T + ++L V CN AS ++S +P + T L PA L Sbjct: 164 LVDIGQATNNRSNLVRPPV---ICNAPASC-----LPESSNDRPVTANTTSLPPAAHL 213 >gi|38044112 restin isoform b [Homo sapiens] Length = 1392 Score = 45.1 bits (105), Expect = 2e-04 Identities = 65/357 (18%), Positives = 138/357 (38%), Gaps = 42/357 (11%) Query: 220 VKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYG 279 +K D+ +L N F+ SI+ + + + +K + K ++ Sbjct: 907 LKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS--- 963 Query: 280 GTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVD---------DI 330 L+ K + C+ +YE T +H Q+ Q ++D + Sbjct: 964 ----DLEKKMETSHNQCQELKARYERA-TSETKTKHEEILQNLQKTLLDTEDKLKGAREE 1018 Query: 331 VSKLVFDFVEYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDT 390 S L+ + E K K K + + ++ + +KTE +E + Q + Sbjct: 1019 NSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELD 1078 Query: 391 TVKEQNFLYKETQETEKKLLFI-SEPIPHPSNELRGLNEKMSNKCSMLSTAE-------D 442 T+KE N E K+LL + ++ + E+ L + + K LS + + Sbjct: 1079 TLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAE 1138 Query: 443 DIRQNFTQLPLHKNKQECILDISEHTLSENDLEELR---------VDHYKCNIQASVHV- 492 ++ ++ ++ H+ +E E ++ N L E++ D K ++Q S+ + Sbjct: 1139 ELGRSRDEVTSHQKLEE------ERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISIT 1192 Query: 493 SDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIF-THDSGLITINSSQEHLTVQAK 548 S T+ K +++ + ++ K LHS+ T +S + + ++L +Q K Sbjct: 1193 SALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLK 1249 Score = 30.4 bits (67), Expect = 5.6 Identities = 53/249 (21%), Positives = 112/249 (44%), Gaps = 43/249 (17%) Query: 254 DVDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSE 313 +V K +S + + +L + DG + ++L+ K + + E ++ +L L E Sbjct: 377 EVAKATSHVGEIEQELALARDG--HDQHVLELEAKMDQLRTMVEAADREKVELLNQL--E 432 Query: 314 QHRNFAQSNQYQVVDDIVSKLVFD---------FVEYEKDTPKKKR----IKYSVGSLSP 360 + + + Q++V ++ ++K + +E EKD + + ++ + S P Sbjct: 433 EEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKP 492 Query: 361 -----VSASVLKKTEQ-KEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISE 414 +S S+L++ +EK+E +++ D Q + T++KE +ET + E K L+ + Sbjct: 493 AGDVDMSLSLLQEISSLQEKLE---VTRTDHQREITSLKEHFGAREETHQKEIKALYTA- 548 Query: 415 PIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDL 474 + +L NE + +K + D+ + L K+K E I+ H + + Sbjct: 549 -----TEKLSKENESLKSKLEHANKENSDV------IALWKSKLETA--IASH---QQAM 592 Query: 475 EELRVDHYK 483 EEL+V K Sbjct: 593 EELKVSFSK 601 Score = 30.0 bits (66), Expect = 7.3 Identities = 51/246 (20%), Positives = 100/246 (40%), Gaps = 42/246 (17%) Query: 255 VDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQ 314 +D +S K T+ KL D D S + + + KK + E ++ + LE +E Sbjct: 713 IDNFTSQLKATEEKL---LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAES 769 Query: 315 HRNFAQSNQYQVVDDIVSKLVFDFVEYE--KDTPKKK----RIKYSVGSLSPVSAS---- 364 + + + + Q + ++ L + E K+T +K+ + K++ S VS Sbjct: 770 SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 829 Query: 365 -VLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNEL 423 + K QKE E ++ D ++ + + ++E E E++L+ E + N++ Sbjct: 830 ETVNKLHQKE--EQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKL---ENDI 884 Query: 424 RGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYK 483 + + + S L+ D++R L E D+EEL++ K Sbjct: 885 AEIMKMSGDNSSQLTKMNDELR-----------------------LKERDVEELQLKLTK 921 Query: 484 CNIQAS 489 N AS Sbjct: 922 ANENAS 927 >gi|4506751 restin isoform a [Homo sapiens] Length = 1427 Score = 45.1 bits (105), Expect = 2e-04 Identities = 65/357 (18%), Positives = 138/357 (38%), Gaps = 42/357 (11%) Query: 220 VKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYG 279 +K D+ +L N F+ SI+ + + + +K + K ++ Sbjct: 942 LKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS--- 998 Query: 280 GTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVD---------DI 330 L+ K + C+ +YE T +H Q+ Q ++D + Sbjct: 999 ----DLEKKMETSHNQCQELKARYERA-TSETKTKHEEILQNLQKTLLDTEDKLKGAREE 1053 Query: 331 VSKLVFDFVEYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDT 390 S L+ + E K K K + + ++ + +KTE +E + Q + Sbjct: 1054 NSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELD 1113 Query: 391 TVKEQNFLYKETQETEKKLLFI-SEPIPHPSNELRGLNEKMSNKCSMLSTAE-------D 442 T+KE N E K+LL + ++ + E+ L + + K LS + + Sbjct: 1114 TLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAE 1173 Query: 443 DIRQNFTQLPLHKNKQECILDISEHTLSENDLEELR---------VDHYKCNIQASVHV- 492 ++ ++ ++ H+ +E E ++ N L E++ D K ++Q S+ + Sbjct: 1174 ELGRSRDEVTSHQKLEE------ERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISIT 1227 Query: 493 SDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIF-THDSGLITINSSQEHLTVQAK 548 S T+ K +++ + ++ K LHS+ T +S + + ++L +Q K Sbjct: 1228 SALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLK 1284 Score = 30.0 bits (66), Expect = 7.3 Identities = 51/246 (20%), Positives = 100/246 (40%), Gaps = 42/246 (17%) Query: 255 VDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQ 314 +D +S K T+ KL D D S + + + KK + E ++ + LE +E Sbjct: 748 IDNFTSQLKATEEKL---LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAES 804 Query: 315 HRNFAQSNQYQVVDDIVSKLVFDFVEYE--KDTPKKK----RIKYSVGSLSPVSAS---- 364 + + + + Q + ++ L + E K+T +K+ + K++ S VS Sbjct: 805 SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 864 Query: 365 -VLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNEL 423 + K QKE E ++ D ++ + + ++E E E++L+ E + N++ Sbjct: 865 ETVNKLHQKE--EQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKL---ENDI 919 Query: 424 RGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYK 483 + + + S L+ D++R L E D+EEL++ K Sbjct: 920 AEIMKMSGDNSSQLTKMNDELR-----------------------LKERDVEELQLKLTK 956 Query: 484 CNIQAS 489 N AS Sbjct: 957 ANENAS 962 Score = 29.6 bits (65), Expect = 9.5 Identities = 56/235 (23%), Positives = 109/235 (46%), Gaps = 39/235 (16%) Query: 266 QVKLRIQTDGDKYGGTSIQLQLKEKK-KKGYCECCLQ----KYEDLETHLLSEQHRNFAQ 320 +V+L Q + +K +Q +++E+ KG E + + ++LE LL E+ + A Sbjct: 424 KVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTK--AD 481 Query: 321 SNQYQVVDDIVSKLVFD--FVEYEKDTPKKKR----IKYSVGSLSP-----VSASVLKKT 369 Q ++ D V+ + +E EKD + + ++ + S P +S S+L++ Sbjct: 482 KLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEI 541 Query: 370 EQ-KEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELRGLNE 428 +EK+E +++ D Q + T++KE +ET + E K L+ + + +L NE Sbjct: 542 SSLQEKLE---VTRTDHQREITSLKEHFGAREETHQKEIKALYTA------TEKLSKENE 592 Query: 429 KMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYK 483 + +K + D+ + L K+K E I+ H + +EEL+V K Sbjct: 593 SLKSKLEHANKENSDV------IALWKSKLETA--IASH---QQAMEELKVSFSK 636 >gi|148612801 KIAA1009 protein [Homo sapiens] Length = 1403 Score = 43.1 bits (100), Expect = 8e-04 Identities = 74/310 (23%), Positives = 122/310 (39%), Gaps = 45/310 (14%) Query: 189 LKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQK 248 L+ STS + K + SG + + L KP K E T N + Sbjct: 542 LRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLS---------TRKKSENPTETD 592 Query: 249 PCSPFDVDKPSSMQKQTQVKL----RIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYE 304 C F D + + KL R+Q DK+ G L E+ K + E K + Sbjct: 593 SCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQA---LIEQIKATFSE----KEK 645 Query: 305 DLET---HLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLSPV 361 +LE L +Q + + NQ D+ + + E +T KK+R + + PV Sbjct: 646 ELENKLEELKKQQEKELFKLNQ----DNYILQAKLSSFE---ETNKKQRWLHFGEAADPV 698 Query: 362 SASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSN 421 + LK+ QKE E + + Q QE++ + L ++ ++ E+++ ++ + + Sbjct: 699 TGEKLKQI-QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSL---FS 754 Query: 422 ELRGLNEKMSNKCSMLSTAEDDI---RQNFTQL-----PLHKNKQECILDISEHTLSEND 473 E+ L E+M + ED QNFT L K K + DI + D Sbjct: 755 EVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKR---LKQD 811 Query: 474 LEELRVDHYK 483 + L VD K Sbjct: 812 KQALEVDFEK 821 >gi|144226234 metastasis suppressor 1 [Homo sapiens] Length = 755 Score = 41.2 bits (95), Expect = 0.003 Identities = 67/281 (23%), Positives = 121/281 (43%), Gaps = 54/281 (19%) Query: 314 QHRNF-AQSNQYQ--VVDDIVSKLVFDFVEYEK-----DTPKKKRIKYSVGSLSPVSASV 365 +HR+ A+ Q+ ++D +++ L E++K D K K + + S+ Sbjct: 85 RHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDT 144 Query: 366 LKKTEQKEKVELQHISQKDCQED-DTTVKEQNFLYKETQETEKKLL-------------F 411 LK ++ +K + D Q D+ +++ N Y +ETEK+ + F Sbjct: 145 LKLQKKAKK------GRGDIQPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTF 198 Query: 412 ISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLP--LHKNKQECILDI----- 464 IS P E+ L E + L T +D++ + T P L + ++ ILD+ Sbjct: 199 ISMLRPVIEEEISMLGE-----ITHLQTISEDLK-SLTMDPHKLPSSSEQVILDLKGSDY 252 Query: 465 --SEHTLSENDLEELRVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKD 522 S T + + C+ SV+ SD + +SGS S + + +L ++ Sbjct: 253 SWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSD--SRSSGSHSHSPSSHYRYRSSNLAQQA 310 Query: 523 ---LHSIFTHDSGLITINSSQEHLTVQAKAPFHTPPEEPNE 560 L S+ +HDSG I+ ++ Q+K+P PPE PN+ Sbjct: 311 PVRLSSVSSHDSGFISQDA------FQSKSPSPMPPEAPNQ 345 >gi|34878777 ring finger protein 20 [Homo sapiens] Length = 975 Score = 39.7 bits (91), Expect = 0.009 Identities = 47/242 (19%), Positives = 100/242 (41%), Gaps = 17/242 (7%) Query: 254 DVDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSE 313 ++ K QK+ ++ L + K +QL EKK K E Q+ +DLE E Sbjct: 632 ELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKE 691 Query: 314 QHRNFAQSNQYQVVDDIVSKL--VFDFVEY-EKDTPKKKRIKYSVGSLSPVSASVLKKTE 370 N+ +D + K+ V + +EY +K K+ + ++ S V+ + + Sbjct: 692 --------NKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQ 743 Query: 371 QKEKVELQHISQKD------CQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELR 424 ++ +Q + +KD E + + L +E +E ++L + + +R Sbjct: 744 EQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVR 803 Query: 425 GLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYKC 484 L EK S + T E ++ L ++K K +++ ++ +L + ++ ++ Sbjct: 804 KLEEKEHLLQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQD 863 Query: 485 NI 486 I Sbjct: 864 EI 865 >gi|158187521 A-kinase anchor protein 5 [Homo sapiens] Length = 427 Score = 38.5 bits (88), Expect = 0.020 Identities = 52/225 (23%), Positives = 93/225 (41%), Gaps = 13/225 (5%) Query: 416 IPHPSNELRGLNEKM--SNKCSMLSTAEDDIRQNFTQLPLHKN--KQECILDISEHTLSE 471 I P R + K+ + CS+ E +I TQ PL+ K + D+SE +S Sbjct: 130 IKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEG-ISR 188 Query: 472 NDLEELRVDHYKCNIQASVHVS--DFSTDNSGSQPKQKSDTVLFPAKDLKEK-DLHSIFT 528 D +E+ + + + V + DN G Q +L + +KEK D+ Sbjct: 189 KDGDEVCESNVSNSTTSGEKVISVELGLDN-GHSAIQTGTLILEEIETIKEKQDVQP--Q 245 Query: 529 HDSGLITINSSQEHLTVQAKAPFHTPPEEP--NECDFKNMDSLPSGKIHRKVKIILGRNR 586 S L T + + + P P++ E ++S P+GK + +I+ + Sbjct: 246 QASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETK 305 Query: 587 KENLEPNAEFDKRTEFITQEENRICSSPVQSLLDLFQTSEEKSEF 631 ++ E + E D + IT+E+++ S + + T E SEF Sbjct: 306 PKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEF 350 >gi|115648142 centrosomal protein 164kDa [Homo sapiens] Length = 1460 Score = 38.1 bits (87), Expect = 0.027 Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 22/192 (11%) Query: 365 VLKKTEQKEKVELQHIS-QKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNEL 423 V ++T ++EK +L + Q + ++ T Q +E Q+ LL ++ + +EL Sbjct: 947 VQEETARREKQQLLDVQRQVALKSEEATATHQQL--EEAQKEHTHLLQSNQQLREILDEL 1004 Query: 424 RGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYK 483 + K+ ++ +L ++++F+ L K++ H L E +EE ++ Sbjct: 1005 QARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQ-------HLLREVTVEE---NNAS 1054 Query: 484 CNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHD------SGLITIN 537 + + +H+ D +Q K+ S ++ +DL L S+ +H+ + + + Sbjct: 1055 PHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLY---LDSLSSHNVWHLLSAEGVALR 1111 Query: 538 SSQEHLTVQAKA 549 S++E L Q ++ Sbjct: 1112 SAKEFLVQQTRS 1123 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 38.1 bits (87), Expect = 0.027 Identities = 74/349 (21%), Positives = 143/349 (40%), Gaps = 35/349 (10%) Query: 173 DDIRYYIE-------QKKKELYL----LKKSSTSVRDGGKRVGSG-AQKTRTGRLKKPFV 220 D +R YI Q K+EL + LK+ ++ + + V AQ T L+K Sbjct: 1217 DHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHT 1276 Query: 221 KVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTD----GD 276 K+++ + L N+ ++ + Q+ + ++ S K + RI+ + + Sbjct: 1277 KLQEEIPVLHEEQELLPNVKEVSET-QETMNELELLTEQSTTKDSTTLARIEMERLRLNE 1335 Query: 277 KYGGTSIQLQLKEKKK---KGYCECCLQKYEDLETHL------LSEQHRNFAQSNQYQVV 327 K+ + +++ K++ K E K++ L+ H+ + E QS + Sbjct: 1336 KFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK 1395 Query: 328 DDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLSP--VSASVLKKTEQKEKVELQHISQKDC 385 D+ +K+V + +++ RI+ + LS + K+ KEK +LQ + + Sbjct: 1396 DNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQ 1455 Query: 386 QEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLST------ 439 E D + + + ETE++L + + L +S K + +ST Sbjct: 1456 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLE 1515 Query: 440 AEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYKCNIQA 488 A +D QN Q K +Q I ISE N+L++ + +H K A Sbjct: 1516 AINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFK-EHRKAKDSA 1563 >gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] Length = 3907 Score = 37.7 bits (86), Expect = 0.035 Identities = 105/537 (19%), Positives = 202/537 (37%), Gaps = 103/537 (19%) Query: 179 IEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTN 238 IE++KK L L K +T+ + G+ QK + +K +++ + Q R ++ Sbjct: 339 IEEEKKTLELKDKLTTADKLLGELQEQIVQKNQ--EIKNMKLELTNSKQKERQSSEEIKQ 396 Query: 239 MPFINYSIQK---PCSPFDVDKPSSMQKQTQVKL-RIQTDGDKYGGTSIQLQLKEKKKKG 294 + +QK S F+ D M+++TQ KL +++ + D+ G I +Q+K++ + Sbjct: 397 LMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI-VQMKQELIRQ 455 Query: 295 YCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYS 354 + + + E+++T E Y T + +IK Sbjct: 456 H----MAQMEEMKTRHKGEMENALRS--------------------YSNITVNEDQIKLM 491 Query: 355 VGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISE 414 +++ ++ + QKEK++ +E ++E+ L ++ ++ ++L F E Sbjct: 492 NVAINELNIKLQDTNSQKEKLK---------EELGLILEEKCALQRQLEDLVEELSFSRE 542 Query: 415 PIPHPSNELRGLNEKMSNKCSMLSTAED---------------------DIRQNFTQLPL 453 I + K++ LST ED ++ +L + Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602 Query: 454 HKNKQECILD-------------------ISEHTLS--ENDLE-ELRVDHYKCNIQASVH 491 + ++ +LD E LS + DLE E R++ K +H Sbjct: 603 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIH 662 Query: 492 VSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIF----THDSGLITINSSQEHLTVQA 547 D ++ QK +T+ F +L K I D +NS E +T+Q Sbjct: 663 YKQ-QIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQI 721 Query: 548 KAPFHTPPEEPNECDFKNMDSLPSGKIHRKV-KIILGRNRKENLEPNAEFDKRTEFITQE 606 E E + + G + ++V ++ L E E D + +F E Sbjct: 722 N-------ELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 774 Query: 607 -ENRICSSPVQSLLDLFQ-----TSEEKSEFLGFTSYTEKSGIC-NVLDIWEEENSD 656 EN I ++L D+ + + EE+ FL K + ++I EEN D Sbjct: 775 AENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENED 831 Score = 33.5 bits (75), Expect = 0.66 Identities = 71/357 (19%), Positives = 143/357 (40%), Gaps = 82/357 (22%) Query: 283 IQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYE 342 I++ +E+K+KG E +Q+ + L+T LL +Q + + +D+ K F + E Sbjct: 728 IEILRQEEKEKGTLEQEVQELQ-LKTELLEKQMK--------EKENDLQEK----FAQLE 774 Query: 343 KDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKET 402 + K K ++ + + V ++++ + L I K +D KE L +E Sbjct: 775 AENSILKDEKKTLEDMLKIHTPV---SQEERLIFLDSIKSKS--KDSVWEKEIEILIEEN 829 Query: 403 QETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECIL 462 ++ +++ + LNE++ + + S AE + N+ +L + + C+L Sbjct: 830 EDLKQQCI--------------QLNEEIEKQRNTFSFAEKNFEVNYQEL---QEEYACLL 872 Query: 463 DISEHTLSENDLEELRVDHYKCNIQA---SVHVSDFSTDNSGSQPKQKSDTVLFPAKDLK 519 + + + +EL YK ++A +H+ + + + F A+ L+ Sbjct: 873 KVKDDLEDSKNKQELE---YKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLE 929 Query: 520 -----EKD----LHSIFTHDSGLITINSSQEHLTVQAKAPFHTPPEEPNECDFKNMD--S 568 EKD + + + ++ L+ Q K ++ E F N + S Sbjct: 930 MGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLK-------QKHGEISFLNEEVKS 982 Query: 569 LPSGKIH-----RKVKIILGRNRKENLEPNAEFDKRTEFITQEENRICSSPVQSLLD 620 L K R+++II+ NR EN++ C + V SLLD Sbjct: 983 LKQEKEQVSLRCRELEIIINHNRAENVQS------------------CDTQVSSLLD 1021 >gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] Length = 3899 Score = 37.7 bits (86), Expect = 0.035 Identities = 105/537 (19%), Positives = 202/537 (37%), Gaps = 103/537 (19%) Query: 179 IEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTN 238 IE++KK L L K +T+ + G+ QK + +K +++ + Q R ++ Sbjct: 339 IEEEKKTLELKDKLTTADKLLGELQEQIVQKNQ--EIKNMKLELTNSKQKERQSSEEIKQ 396 Query: 239 MPFINYSIQK---PCSPFDVDKPSSMQKQTQVKL-RIQTDGDKYGGTSIQLQLKEKKKKG 294 + +QK S F+ D M+++TQ KL +++ + D+ G I +Q+K++ + Sbjct: 397 LMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI-VQMKQELIRQ 455 Query: 295 YCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYS 354 + + + E+++T E Y T + +IK Sbjct: 456 H----MAQMEEMKTRHKGEMENALRS--------------------YSNITVNEDQIKLM 491 Query: 355 VGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISE 414 +++ ++ + QKEK++ +E ++E+ L ++ ++ ++L F E Sbjct: 492 NVAINELNIKLQDTNSQKEKLK---------EELGLILEEKCALQRQLEDLVEELSFSRE 542 Query: 415 PIPHPSNELRGLNEKMSNKCSMLSTAED---------------------DIRQNFTQLPL 453 I + K++ LST ED ++ +L + Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602 Query: 454 HKNKQECILD-------------------ISEHTLS--ENDLE-ELRVDHYKCNIQASVH 491 + ++ +LD E LS + DLE E R++ K +H Sbjct: 603 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIH 662 Query: 492 VSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIF----THDSGLITINSSQEHLTVQA 547 D ++ QK +T+ F +L K I D +NS E +T+Q Sbjct: 663 YKQ-QIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQI 721 Query: 548 KAPFHTPPEEPNECDFKNMDSLPSGKIHRKV-KIILGRNRKENLEPNAEFDKRTEFITQE 606 E E + + G + ++V ++ L E E D + +F E Sbjct: 722 N-------ELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 774 Query: 607 -ENRICSSPVQSLLDLFQ-----TSEEKSEFLGFTSYTEKSGIC-NVLDIWEEENSD 656 EN I ++L D+ + + EE+ FL K + ++I EEN D Sbjct: 775 AENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENED 831 Score = 33.5 bits (75), Expect = 0.66 Identities = 71/357 (19%), Positives = 143/357 (40%), Gaps = 82/357 (22%) Query: 283 IQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYE 342 I++ +E+K+KG E +Q+ + L+T LL +Q + + +D+ K F + E Sbjct: 728 IEILRQEEKEKGTLEQEVQELQ-LKTELLEKQMK--------EKENDLQEK----FAQLE 774 Query: 343 KDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKET 402 + K K ++ + + V ++++ + L I K +D KE L +E Sbjct: 775 AENSILKDEKKTLEDMLKIHTPV---SQEERLIFLDSIKSKS--KDSVWEKEIEILIEEN 829 Query: 403 QETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECIL 462 ++ +++ + LNE++ + + S AE + N+ +L + + C+L Sbjct: 830 EDLKQQCI--------------QLNEEIEKQRNTFSFAEKNFEVNYQEL---QEEYACLL 872 Query: 463 DISEHTLSENDLEELRVDHYKCNIQA---SVHVSDFSTDNSGSQPKQKSDTVLFPAKDLK 519 + + + +EL YK ++A +H+ + + + F A+ L+ Sbjct: 873 KVKDDLEDSKNKQELE---YKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLE 929 Query: 520 -----EKD----LHSIFTHDSGLITINSSQEHLTVQAKAPFHTPPEEPNECDFKNMD--S 568 EKD + + + ++ L+ Q K ++ E F N + S Sbjct: 930 MGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLK-------QKHGEISFLNEEVKS 982 Query: 569 LPSGKIH-----RKVKIILGRNRKENLEPNAEFDKRTEFITQEENRICSSPVQSLLD 620 L K R+++II+ NR EN++ C + V SLLD Sbjct: 983 LKQEKEQVSLRCRELEIIINHNRAENVQS------------------CDTQVSSLLD 1021 >gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] Length = 446 Score = 37.4 bits (85), Expect = 0.046 Identities = 44/184 (23%), Positives = 82/184 (44%), Gaps = 14/184 (7%) Query: 259 SSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNF 318 S MQ + Q K Q + + + +L+LK K++K Y E L + ++ + SE + Sbjct: 171 SDMQAELQKK---QEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMG 227 Query: 319 AQSNQYQVVDDIVSKLVFDFVEYEKD-TPKKKRIKYSVGSLSPVSASVLKKTEQ-KEKVE 376 + +Q Q K + V+ ++D T + +++K L L TEQ K++ + Sbjct: 228 IRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHL------FLSLTEQRKDQKK 281 Query: 377 LQHISQKDCQEDDTTVKEQNFLYKETQETEKKLL---FISEPIPHPSNELRGLNEKMSNK 433 L+ ++ Q + T +K+Q L E + K+L I + L G N+ + + Sbjct: 282 LEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKRE 341 Query: 434 CSML 437 S L Sbjct: 342 NSRL 345 >gi|9910266 kinesin family member 15 [Homo sapiens] Length = 1388 Score = 36.6 bits (83), Expect = 0.078 Identities = 41/227 (18%), Positives = 99/227 (43%), Gaps = 22/227 (9%) Query: 262 QKQTQVKLRIQTDGDKYGGTSIQLQLKE------KKKKGYCECCLQKYEDLETHLLSEQH 315 +K+ KL +Q + DK + L++ E +K+ CE + K + LE LL+ + Sbjct: 909 EKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEK 968 Query: 316 ----RNFAQSNQYQVVDDIVSKLV---------FDFVEYEKDTPKKKRIKYSVGSLSPVS 362 ++ + +VV D+++++ + ++ K K KY+ + Sbjct: 969 VISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREE 1028 Query: 363 ASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNE 422 + VL K ++ + ++L+ + +D E++ L ++ ++L ++E S Sbjct: 1029 SRVLIKKQEVDILDLKETLRLRILSEDI---ERDMLCEDLAHATEQLNMLTEASKKHSGL 1085 Query: 423 LRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTL 469 L+ E+++ K +++ + + Q ++ KN+ + EH + Sbjct: 1086 LQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVM 1132 >gi|110815815 centlein isoform 1 [Homo sapiens] Length = 1406 Score = 36.6 bits (83), Expect = 0.078 Identities = 86/448 (19%), Positives = 171/448 (38%), Gaps = 58/448 (12%) Query: 173 DDIRYYIEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPF---VKVEDMSQLY 229 D++R E++K+ L +L+ + +V++ K+ G+ T ++K+ ++ ED ++ Sbjct: 553 DELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVW 612 Query: 230 RPF-YLQLTNMPF------INYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYG-GT 281 Y + N + + + +DK + + V R + + G Sbjct: 613 NELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDD 672 Query: 282 SIQLQLKEKKKKGYCECCLQKYEDLETHLLS--EQHRNFAQSNQYQVVDDIVSKLVFDFV 339 ++ EK K E LQK +LE L S ++ R + N+ + ++ K + Sbjct: 673 EVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQ 732 Query: 340 EYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQ---- 395 + + +T +K+ + GS K +KE ELQ + + + + T+++ Q Sbjct: 733 QEDTETREKELEQIIKGS----------KDVEKENTELQ-VKISELETEVTSLRRQVAEA 781 Query: 396 NFLYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHK 455 N L E +E + + +E+ + + + D + T++ Sbjct: 782 NALRNENEELINPMEKSHQSADRAKSEMATMK---------VRSGRYDCKTTMTKVKFKA 832 Query: 456 NKQECILDISEHTLSENDLEELRVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLF-- 513 K+ C + HT+ + ++ + + VS+ S+D S +Q Q T++ Sbjct: 833 AKKNCSVG-RHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSD-SEAQTSQTLGTIIVET 890 Query: 514 --------PAKDLKEKDLHSIFTHDSGLITINSSQEHLTVQAKAP---FHTPPEEPNECD 562 KD KE D T DS Q +L + K P FH + Sbjct: 891 SQKISPTEDGKDQKESDP----TEDSQTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQ 946 Query: 563 FKNMDSLPSGKIHRKVKIILGRNRKENL 590 KN S H V + R + +N+ Sbjct: 947 KKNCKMQKSS--HTAVPTRVNREKYKNI 972 >gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform a [Homo sapiens] Length = 1216 Score = 35.0 bits (79), Expect = 0.23 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 11/113 (9%) Query: 341 YEKDTPKKKRIKYSVGSLSPVSASV-------LKKTEQKEKVELQHISQKDCQEDDTTVK 393 Y + K++ IK + L+ V+ LK+ +KEK EL+ K QE T K Sbjct: 1025 YSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK 1084 Query: 394 EQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQ 446 ++ E ++TE +I E + + ++ L E S + L +IRQ Sbjct: 1085 SKDKSQMEEEKTEMIRSYIQEVVQY----IKRLEEAQSKRQEKLVEKHKEIRQ 1133 >gi|33356544 phosphoinositide-specific phospholipase C beta 1 isoform b [Homo sapiens] Length = 1173 Score = 35.0 bits (79), Expect = 0.23 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 11/113 (9%) Query: 341 YEKDTPKKKRIKYSVGSLSPVSASV-------LKKTEQKEKVELQHISQKDCQEDDTTVK 393 Y + K++ IK + L+ V+ LK+ +KEK EL+ K QE T K Sbjct: 1025 YSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK 1084 Query: 394 EQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQ 446 ++ E ++TE +I E + + ++ L E S + L +IRQ Sbjct: 1085 SKDKSQMEEEKTEMIRSYIQEVVQY----IKRLEEAQSKRQEKLVEKHKEIRQ 1133 >gi|4758650 kinesin family member 5C [Homo sapiens] Length = 957 Score = 34.7 bits (78), Expect = 0.30 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 19/127 (14%) Query: 370 EQKEKV--ELQHISQKDCQEDDTTVKEQNFLYKETQETE---KKLLFISEPIPHPSNELR 424 E+K+K+ E++ ++QK E + + N L E QE E +KLL +++ +L+ Sbjct: 726 EEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLK 785 Query: 425 GLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEH----------TLSENDL 474 GL E +S + L ++R+ F Q + K+ LD + + EN+L Sbjct: 786 GLEETVSRELQTL----HNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNL 841 Query: 475 EELRVDH 481 E+L H Sbjct: 842 EQLTKVH 848 >gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] Length = 983 Score = 34.7 bits (78), Expect = 0.30 Identities = 66/349 (18%), Positives = 136/349 (38%), Gaps = 49/349 (14%) Query: 198 DGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDK 257 D G +G + + P V + + + +++ + I +QK + ++ Sbjct: 396 DLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAER 455 Query: 258 PSSMQKQTQVKLR------IQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLL 311 KQ QV+L+ + + + S L K K+ + KYE+ +L Sbjct: 456 -----KQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS-------KYEEAMKEVL 503 Query: 312 SEQHR------------NFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLS 359 S Q + N++ ++ +V ++ ++ L D + + +R K V L Sbjct: 504 SVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL---QNALEESERNKEKVRELE 560 Query: 360 PVSASVLKKTEQKEKVE-LQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFI-----S 413 K T K VE + + C + KE+ FL+++ QE +++++ + S Sbjct: 561 EKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKS 620 Query: 414 EPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSEND 473 + S+E + E M+ L+ ++ Q L+K Q + D + E+ Sbjct: 621 QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ------LYKEAQAELEDYRKRKSLEDV 674 Query: 474 LEEL--RVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKE 520 E + +H K + +VS +++ S+ K + VL LK+ Sbjct: 675 TAEYIHKAEHEK--LMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 721 >gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] Length = 972 Score = 34.7 bits (78), Expect = 0.30 Identities = 66/349 (18%), Positives = 136/349 (38%), Gaps = 49/349 (14%) Query: 198 DGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDK 257 D G +G + + P V + + + +++ + I +QK + ++ Sbjct: 385 DLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAER 444 Query: 258 PSSMQKQTQVKLR------IQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLL 311 KQ QV+L+ + + + S L K K+ + KYE+ +L Sbjct: 445 -----KQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS-------KYEEAMKEVL 492 Query: 312 SEQHR------------NFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLS 359 S Q + N++ ++ +V ++ ++ L D + + +R K V L Sbjct: 493 SVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL---QNALEESERNKEKVRELE 549 Query: 360 PVSASVLKKTEQKEKVE-LQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFI-----S 413 K T K VE + + C + KE+ FL+++ QE +++++ + S Sbjct: 550 EKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKS 609 Query: 414 EPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSEND 473 + S+E + E M+ L+ ++ Q L+K Q + D + E+ Sbjct: 610 QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ------LYKEAQAELEDYRKRKSLEDV 663 Query: 474 LEEL--RVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKE 520 E + +H K + +VS +++ S+ K + VL LK+ Sbjct: 664 TAEYIHKAEHEK--LMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 710 >gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] Length = 951 Score = 34.7 bits (78), Expect = 0.30 Identities = 66/349 (18%), Positives = 136/349 (38%), Gaps = 49/349 (14%) Query: 198 DGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDK 257 D G +G + + P V + + + +++ + I +QK + ++ Sbjct: 364 DLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAER 423 Query: 258 PSSMQKQTQVKLR------IQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLL 311 KQ QV+L+ + + + S L K K+ + KYE+ +L Sbjct: 424 -----KQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS-------KYEEAMKEVL 471 Query: 312 SEQHR------------NFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLS 359 S Q + N++ ++ +V ++ ++ L D + + +R K V L Sbjct: 472 SVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL---QNALEESERNKEKVRELE 528 Query: 360 PVSASVLKKTEQKEKVE-LQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFI-----S 413 K T K VE + + C + KE+ FL+++ QE +++++ + S Sbjct: 529 EKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKS 588 Query: 414 EPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSEND 473 + S+E + E M+ L+ ++ Q L+K Q + D + E+ Sbjct: 589 QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ------LYKEAQAELEDYRKRKSLEDV 642 Query: 474 LEEL--RVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKE 520 E + +H K + +VS +++ S+ K + VL LK+ Sbjct: 643 TAEYIHKAEHEK--LMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 689 >gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 34.7 bits (78), Expect = 0.30 Identities = 66/349 (18%), Positives = 136/349 (38%), Gaps = 49/349 (14%) Query: 198 DGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDK 257 D G +G + + P V + + + +++ + I +QK + ++ Sbjct: 393 DLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAER 452 Query: 258 PSSMQKQTQVKLR------IQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLL 311 KQ QV+L+ + + + S L K K+ + KYE+ +L Sbjct: 453 -----KQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS-------KYEEAMKEVL 500 Query: 312 SEQHR------------NFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLS 359 S Q + N++ ++ +V ++ ++ L D + + +R K V L Sbjct: 501 SVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL---QNALEESERNKEKVRELE 557 Query: 360 PVSASVLKKTEQKEKVE-LQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFI-----S 413 K T K VE + + C + KE+ FL+++ QE +++++ + S Sbjct: 558 EKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKS 617 Query: 414 EPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSEND 473 + S+E + E M+ L+ ++ Q L+K Q + D + E+ Sbjct: 618 QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ------LYKEAQAELEDYRKRKSLEDV 671 Query: 474 LEEL--RVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKE 520 E + +H K + +VS +++ S+ K + VL LK+ Sbjct: 672 TAEYIHKAEHEK--LMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 718 >gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 34.7 bits (78), Expect = 0.30 Identities = 66/349 (18%), Positives = 136/349 (38%), Gaps = 49/349 (14%) Query: 198 DGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDK 257 D G +G + + P V + + + +++ + I +QK + ++ Sbjct: 393 DLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAER 452 Query: 258 PSSMQKQTQVKLR------IQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLL 311 KQ QV+L+ + + + S L K K+ + KYE+ +L Sbjct: 453 -----KQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS-------KYEEAMKEVL 500 Query: 312 SEQHR------------NFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLS 359 S Q + N++ ++ +V ++ ++ L D + + +R K V L Sbjct: 501 SVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL---QNALEESERNKEKVRELE 557 Query: 360 PVSASVLKKTEQKEKVE-LQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFI-----S 413 K T K VE + + C + KE+ FL+++ QE +++++ + S Sbjct: 558 EKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKS 617 Query: 414 EPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSEND 473 + S+E + E M+ L+ ++ Q L+K Q + D + E+ Sbjct: 618 QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ------LYKEAQAELEDYRKRKSLEDV 671 Query: 474 LEEL--RVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKE 520 E + +H K + +VS +++ S+ K + VL LK+ Sbjct: 672 TAEYIHKAEHEK--LMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 718 >gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 34.7 bits (78), Expect = 0.30 Identities = 66/349 (18%), Positives = 136/349 (38%), Gaps = 49/349 (14%) Query: 198 DGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDK 257 D G +G + + P V + + + +++ + I +QK + ++ Sbjct: 393 DLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAER 452 Query: 258 PSSMQKQTQVKLR------IQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLL 311 KQ QV+L+ + + + S L K K+ + KYE+ +L Sbjct: 453 -----KQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQS-------KYEEAMKEVL 500 Query: 312 SEQHR------------NFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLS 359 S Q + N++ ++ +V ++ ++ L D + + +R K V L Sbjct: 501 SVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL---QNALEESERNKEKVRELE 557 Query: 360 PVSASVLKKTEQKEKVE-LQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFI-----S 413 K T K VE + + C + KE+ FL+++ QE +++++ + S Sbjct: 558 EKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKS 617 Query: 414 EPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSEND 473 + S+E + E M+ L+ ++ Q L+K Q + D + E+ Sbjct: 618 QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ------LYKEAQAELEDYRKRKSLEDV 671 Query: 474 LEEL--RVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKE 520 E + +H K + +VS +++ S+ K + VL LK+ Sbjct: 672 TAEYIHKAEHEK--LMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 718 >gi|194294523 intersectin 2 isoform 3 [Homo sapiens] Length = 1670 Score = 34.7 bits (78), Expect = 0.30 Identities = 55/251 (21%), Positives = 106/251 (42%), Gaps = 48/251 (19%) Query: 262 QKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFAQS 321 Q+Q + + + Q + +++ +LQ +E KK+ E L+K +LE E+ ++ + Sbjct: 388 QQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERR 447 Query: 322 NQYQVVDDIVSKLVFDFV--------------EYEKDTPKKKRIKYSVGSLSPVSASV-- 365 + + +L ++ + E + KKK + + +L+ + Sbjct: 448 EAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISG 507 Query: 366 ------LKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHP 419 LKK QK ++E + K C D + E L +E QE + KL+++ P Sbjct: 508 RLQDVRLKKQTQKTELE---VLDKQC---DLEIMEIKQLQQELQEYQNKLIYLV-----P 556 Query: 420 SNELRGLNEKMSNK---------CSML---STAEDDIRQNFTQLPLHKNKQECILDISEH 467 +L LNE++ N S+L S ++++ Q + L ++E +SE Sbjct: 557 EKQL--LNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKE-QLDALEKETASKLSEM 613 Query: 468 TLSENDLEELR 478 N L+ELR Sbjct: 614 DSFNNQLKELR 624 >gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo sapiens] Length = 638 Score = 34.3 bits (77), Expect = 0.39 Identities = 27/137 (19%), Positives = 55/137 (40%), Gaps = 2/137 (1%) Query: 371 QKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKM 430 Q+EK + QK C + VKE+N +E ++T +L + + ++ L E+ Sbjct: 261 QQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEA 320 Query: 431 SNKCSMLSTAEDDIRQNFTQLPLHK--NKQECILDISEHTLSENDLEELRVDHYKCNIQA 488 ++ L E+ ++ +L + Q +L ++ LE++ Sbjct: 321 KSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALT 380 Query: 489 SVHVSDFSTDNSGSQPK 505 + + D +NS Q K Sbjct: 381 ASEIEDLKLENSSLQEK 397 >gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo sapiens] Length = 725 Score = 34.3 bits (77), Expect = 0.39 Identities = 27/137 (19%), Positives = 55/137 (40%), Gaps = 2/137 (1%) Query: 371 QKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKM 430 Q+EK + QK C + VKE+N +E ++T +L + + ++ L E+ Sbjct: 348 QQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEA 407 Query: 431 SNKCSMLSTAEDDIRQNFTQLPLHK--NKQECILDISEHTLSENDLEELRVDHYKCNIQA 488 ++ L E+ ++ +L + Q +L ++ LE++ Sbjct: 408 KSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALT 467 Query: 489 SVHVSDFSTDNSGSQPK 505 + + D +NS Q K Sbjct: 468 ASEIEDLKLENSSLQEK 484 >gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo sapiens] Length = 709 Score = 34.3 bits (77), Expect = 0.39 Identities = 27/137 (19%), Positives = 55/137 (40%), Gaps = 2/137 (1%) Query: 371 QKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKM 430 Q+EK + QK C + VKE+N +E ++T +L + + ++ L E+ Sbjct: 332 QQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEA 391 Query: 431 SNKCSMLSTAEDDIRQNFTQLPLHK--NKQECILDISEHTLSENDLEELRVDHYKCNIQA 488 ++ L E+ ++ +L + Q +L ++ LE++ Sbjct: 392 KSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALT 451 Query: 489 SVHVSDFSTDNSGSQPK 505 + + D +NS Q K Sbjct: 452 ASEIEDLKLENSSLQEK 468 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.130 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,946,337 Number of Sequences: 37866 Number of extensions: 1291667 Number of successful extensions: 3663 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 133 Number of HSP's that attempted gapping in prelim test: 3525 Number of HSP's gapped (non-prelim): 271 length of query: 674 length of database: 18,247,518 effective HSP length: 109 effective length of query: 565 effective length of database: 14,120,124 effective search space: 7977870060 effective search space used: 7977870060 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.