Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 57165412
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57165412 acyl-CoA synthetase long-chain family member 6
isoform b [Homo sapiens]
(722 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 1470 0.0
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 1446 0.0
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 1004 0.0
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 883 0.0
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 883 0.0
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 883 0.0
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo... 317 2e-86
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo... 317 2e-86
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 305 7e-83
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 305 7e-83
gi|27477105 lipidosin [Homo sapiens] 159 7e-39
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 141 2e-33
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 88 3e-17
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 88 3e-17
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 80 9e-15
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 60 9e-09
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 60 9e-09
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 60 9e-09
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 59 2e-08
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 58 4e-08
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 49 2e-05
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 47 8e-05
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 47 8e-05
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 45 2e-04
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 42 0.003
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 40 0.008
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 39 0.022
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 36 0.14
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 35 0.32
gi|31559829 keratin 25 [Homo sapiens] 33 0.93
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 1470 bits (3806), Expect = 0.0
Identities = 722/722 (100%), Positives = 722/722 (100%)
Query: 1 MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60
MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA
Sbjct: 1 MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60
Query: 61 LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120
LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV
Sbjct: 61 LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120
Query: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180
FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ
Sbjct: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180
Query: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240
NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER
Sbjct: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240
Query: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300
KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF
Sbjct: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300
Query: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVY 360
TSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVY
Sbjct: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVY 360
Query: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420
CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK
Sbjct: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420
Query: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480
RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY
Sbjct: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480
Query: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540
EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV
Sbjct: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540
Query: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600
FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN
Sbjct: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600
Query: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660
IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL
Sbjct: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660
Query: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720
EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI
Sbjct: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720
Query: 721 SM 722
SM
Sbjct: 721 SM 722
>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
a [Homo sapiens]
Length = 722
Score = 1446 bits (3744), Expect = 0.0
Identities = 711/722 (98%), Positives = 714/722 (98%)
Query: 1 MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60
MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA
Sbjct: 1 MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGA 60
Query: 61 LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120
LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV
Sbjct: 61 LAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQV 120
Query: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180
FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ
Sbjct: 121 FRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ 180
Query: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240
NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER
Sbjct: 181 NRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVER 240
Query: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300
KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF
Sbjct: 241 KETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCF 300
Query: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVY 360
TSGTTGNPKGAMLTHGNVVADFSGFLKVTE P DV IS+LPLAHMFER++QSVVY
Sbjct: 301 TSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVY 360
Query: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420
CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK
Sbjct: 361 CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK 420
Query: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480
RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY
Sbjct: 421 RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY 480
Query: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540
EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV
Sbjct: 481 EGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNV 540
Query: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600
FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN
Sbjct: 541 FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIEN 600
Query: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660
IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL
Sbjct: 601 IYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAIL 660
Query: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720
EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI
Sbjct: 661 EDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSI 720
Query: 721 SM 722
SM
Sbjct: 721 SM 722
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 1004 bits (2596), Expect = 0.0
Identities = 466/694 (67%), Positives = 570/694 (82%)
Query: 26 MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85
MQ E+ R R+PEL D Q+ R+L TL+ GA AA+ +W+ RPK L+PPC+L MQ
Sbjct: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
Query: 86 SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145
S EV SGGARRS + + L ++YDD T+Y+ F+RG+ +S NGPCLG RKP QPY+W
Sbjct: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
Query: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205
LSY++VA+ +E +GS L+Q K DQFIG+FAQNRPEW+I+E C+ YSMV+VPLYDT
Sbjct: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
Query: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265
LG AI YI+N A++S V VDKP+KA LLLE VE K PGLK+I++MD + L ERGQ+
Sbjct: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
Query: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325
CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F
Sbjct: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
Query: 326 LKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385
+K TE + P DD LISFLPLAHMFERV++ V+ CHG ++GFFQGDIRLL DD+K L P
Sbjct: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
Query: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445
T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+
Sbjct: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
Query: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505
Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC T PGDWT+GHV
Sbjct: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
Query: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565
GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD
Sbjct: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
Query: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625
IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I
Sbjct: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
Query: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685
VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL FEQVK I +H
Sbjct: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
Query: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719
++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS
Sbjct: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 883 bits (2281), Expect = 0.0
Identities = 420/672 (62%), Positives = 535/672 (79%), Gaps = 2/672 (0%)
Query: 47 FRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQL 106
F L L+ + A + W RP+ + P +L QS +E GGAR+ V L
Sbjct: 9 FSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIE--GGARKGVSQKNNDL 66
Query: 107 LTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHN 166
+ + DA+TMY+VF+RGL++S NGPCLG+RKP QPY+WLSY++V+DRAE+LGS LL
Sbjct: 67 TSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKG 126
Query: 167 CKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVD 226
K+ DQF+G+FAQNRPEWII ELACYTYSMV VPLYDTLGP AI +I+N ADI+ VI D
Sbjct: 127 YKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICD 186
Query: 227 KPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQA 286
PQKA++L+ +VE+ TP LK+IILMDPF++ LK+RG+K G+ I S+ E+ G+E+ +
Sbjct: 187 TPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRK 246
Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLP 346
PVPP P+DLS++CFTSGTTG+PKGAM+TH N+V++ + FLK E P DDV IS+LP
Sbjct: 247 PVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLP 306
Query: 347 LAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQA 406
LAHMFER++Q+VVY G RVGFFQGDIRLL+DDMK L PT+FP VPRLLNR+YDK+ ++A
Sbjct: 307 LAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEA 366
Query: 407 NTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPT 466
TPLK++LL+ A K E++ GIIR+DS WD+L F KIQ SLGG VR+IVTGAAP S +
Sbjct: 367 KTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTS 426
Query: 467 VLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWA 526
V+ F RAA+GCQVYE YGQTECT GCTFT PGDWTSGHVG PL CN++KL DV ++NY+
Sbjct: 427 VMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFT 486
Query: 527 CKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFK 586
EGE+C++G NVFKGYLKDP++T+EALDSDGWLHTGDIG+WLP GTLKIIDRKK+IFK
Sbjct: 487 VNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFK 546
Query: 587 LAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTY 646
LAQGEY+APEKIENIY RSQPV QI+VHG+SL++ LVG+VVPD +V+PS+A K G++G++
Sbjct: 547 LAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSF 606
Query: 647 ADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPEL 706
+LC N+ +++AILED+ ++GKESGL +FEQVKAI +H + FS++NGLLTPTLKAKR EL
Sbjct: 607 EELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGEL 666
Query: 707 REYFKKQIEELY 718
+YF+ QI+ LY
Sbjct: 667 SKYFRTQIDSLY 678
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 883 bits (2281), Expect = 0.0
Identities = 420/672 (62%), Positives = 535/672 (79%), Gaps = 2/672 (0%)
Query: 47 FRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQL 106
F L L+ + A + W RP+ + P +L QS +E GGAR+ V L
Sbjct: 9 FSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIE--GGARKGVSQKNNDL 66
Query: 107 LTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHN 166
+ + DA+TMY+VF+RGL++S NGPCLG+RKP QPY+WLSY++V+DRAE+LGS LL
Sbjct: 67 TSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKG 126
Query: 167 CKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVD 226
K+ DQF+G+FAQNRPEWII ELACYTYSMV VPLYDTLGP AI +I+N ADI+ VI D
Sbjct: 127 YKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICD 186
Query: 227 KPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQA 286
PQKA++L+ +VE+ TP LK+IILMDPF++ LK+RG+K G+ I S+ E+ G+E+ +
Sbjct: 187 TPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRK 246
Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLP 346
PVPP P+DLS++CFTSGTTG+PKGAM+TH N+V++ + FLK E P DDV IS+LP
Sbjct: 247 PVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLP 306
Query: 347 LAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQA 406
LAHMFER++Q+VVY G RVGFFQGDIRLL+DDMK L PT+FP VPRLLNR+YDK+ ++A
Sbjct: 307 LAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEA 366
Query: 407 NTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPT 466
TPLK++LL+ A K E++ GIIR+DS WD+L F KIQ SLGG VR+IVTGAAP S +
Sbjct: 367 KTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTS 426
Query: 467 VLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWA 526
V+ F RAA+GCQVYE YGQTECT GCTFT PGDWTSGHVG PL CN++KL DV ++NY+
Sbjct: 427 VMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFT 486
Query: 527 CKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFK 586
EGE+C++G NVFKGYLKDP++T+EALDSDGWLHTGDIG+WLP GTLKIIDRKK+IFK
Sbjct: 487 VNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFK 546
Query: 587 LAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTY 646
LAQGEY+APEKIENIY RSQPV QI+VHG+SL++ LVG+VVPD +V+PS+A K G++G++
Sbjct: 547 LAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSF 606
Query: 647 ADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPEL 706
+LC N+ +++AILED+ ++GKESGL +FEQVKAI +H + FS++NGLLTPTLKAKR EL
Sbjct: 607 EELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGEL 666
Query: 707 REYFKKQIEELY 718
+YF+ QI+ LY
Sbjct: 667 SKYFRTQIDSLY 678
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 883 bits (2281), Expect = 0.0
Identities = 420/672 (62%), Positives = 535/672 (79%), Gaps = 2/672 (0%)
Query: 47 FRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQL 106
F L L+ + A + W RP+ + P +L QS +E GGAR+ V L
Sbjct: 65 FSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIE--GGARKGVSQKNNDL 122
Query: 107 LTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHN 166
+ + DA+TMY+VF+RGL++S NGPCLG+RKP QPY+WLSY++V+DRAE+LGS LL
Sbjct: 123 TSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKG 182
Query: 167 CKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVD 226
K+ DQF+G+FAQNRPEWII ELACYTYSMV VPLYDTLGP AI +I+N ADI+ VI D
Sbjct: 183 YKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICD 242
Query: 227 KPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQA 286
PQKA++L+ +VE+ TP LK+IILMDPF++ LK+RG+K G+ I S+ E+ G+E+ +
Sbjct: 243 TPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRK 302
Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLP 346
PVPP P+DLS++CFTSGTTG+PKGAM+TH N+V++ + FLK E P DDV IS+LP
Sbjct: 303 PVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLP 362
Query: 347 LAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQA 406
LAHMFER++Q+VVY G RVGFFQGDIRLL+DDMK L PT+FP VPRLLNR+YDK+ ++A
Sbjct: 363 LAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEA 422
Query: 407 NTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPT 466
TPLK++LL+ A K E++ GIIR+DS WD+L F KIQ SLGG VR+IVTGAAP S +
Sbjct: 423 KTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTS 482
Query: 467 VLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWA 526
V+ F RAA+GCQVYE YGQTECT GCTFT PGDWTSGHVG PL CN++KL DV ++NY+
Sbjct: 483 VMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFT 542
Query: 527 CKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFK 586
EGE+C++G NVFKGYLKDP++T+EALDSDGWLHTGDIG+WLP GTLKIIDRKK+IFK
Sbjct: 543 VNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFK 602
Query: 587 LAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTY 646
LAQGEY+APEKIENIY RSQPV QI+VHG+SL++ LVG+VVPD +V+PS+A K G++G++
Sbjct: 603 LAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSF 662
Query: 647 ADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPEL 706
+LC N+ +++AILED+ ++GKESGL +FEQVKAI +H + FS++NGLLTPTLKAKR EL
Sbjct: 663 EELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGEL 722
Query: 707 REYFKKQIEELY 718
+YF+ QI+ LY
Sbjct: 723 SKYFRTQIDSLY 734
>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 317 bits (812), Expect = 2e-86
Identities = 198/599 (33%), Positives = 319/599 (53%), Gaps = 36/599 (6%)
Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Y WLSY++V RA G+GL K T+ I +F + R EW+I AC+ Y+ +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQKPKTN--IAIFCETRAEWMIAAQACFMYNFQLVTL 189
Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKER 262
Y TLG AI + +N +++ +I K L + V P L+ II +D E
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSL--VPRLRHIITVDGKPPTWSEF 247
Query: 263 GQKCGVVIKSMQAVEDCGQE---NHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVV 319
+ G+++ +M AVE G + +Q P P D++++ +TSG+TG PKG M++H N++
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
Query: 320 ADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSD- 378
A +G + E++ ++DV I +LPLAH+ E + V HG R+G+ + L+D
Sbjct: 306 AGITG---MAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
Query: 379 ----------DMKALCPTIFPVVPRLLNRMYDKIFSQAN--TPLKRWLLEFAAKRKQAEV 426
D L PT+ VP +++R+Y + ++ + + +R L A K ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
Query: 427 RSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQT 486
G RN + D F K+++ LGG +R+++ G AP S T F+ C V +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
Query: 487 ECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKG---EGEICVRGPNVFKG 543
E T + D+ +G VGAPL C IKL + EE Y+ GEI + G +V G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
Query: 544 YLKDPDRTKEAL--DSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIE 599
Y K+ +TK D +G WL TGDIG++ P G LKIIDRKK + KL GEYV+ K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Query: 600 NIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAI 659
V I + +S ++++G VVP+ + + A+K+G++GT+ +LC + +++ +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
Query: 660 LEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
L+ + + L FE I + + ++ + GL+T K KR EL+ +++ IE +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 317 bits (812), Expect = 2e-86
Identities = 198/599 (33%), Positives = 319/599 (53%), Gaps = 36/599 (6%)
Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Y WLSY++V RA G+GL K T+ I +F + R EW+I AC+ Y+ +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQKPKTN--IAIFCETRAEWMIAAQACFMYNFQLVTL 189
Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKER 262
Y TLG AI + +N +++ +I K L + V P L+ II +D E
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSL--VPRLRHIITVDGKPPTWSEF 247
Query: 263 GQKCGVVIKSMQAVEDCGQE---NHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVV 319
+ G+++ +M AVE G + +Q P P D++++ +TSG+TG PKG M++H N++
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
Query: 320 ADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSD- 378
A +G + E++ ++DV I +LPLAH+ E + V HG R+G+ + L+D
Sbjct: 306 AGITG---MAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
Query: 379 ----------DMKALCPTIFPVVPRLLNRMYDKIFSQAN--TPLKRWLLEFAAKRKQAEV 426
D L PT+ VP +++R+Y + ++ + + +R L A K ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
Query: 427 RSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQT 486
G RN + D F K+++ LGG +R+++ G AP S T F+ C V +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
Query: 487 ECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKG---EGEICVRGPNVFKG 543
E T + D+ +G VGAPL C IKL + EE Y+ GEI + G +V G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
Query: 544 YLKDPDRTKEAL--DSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIE 599
Y K+ +TK D +G WL TGDIG++ P G LKIIDRKK + KL GEYV+ K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Query: 600 NIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAI 659
V I + +S ++++G VVP+ + + A+K+G++GT+ +LC + +++ +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
Query: 660 LEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
L+ + + L FE I + + ++ + GL+T K KR EL+ +++ IE +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 305 bits (782), Expect = 7e-83
Identities = 199/602 (33%), Positives = 312/602 (51%), Gaps = 42/602 (6%)
Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Y+W++Y EV R GSGL K I +F + R EW+I C+ Y+ +V L
Sbjct: 82 YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259
Y TLG A+ + +N ++ S +I +V LLE + + +K II +D +A+
Sbjct: 140 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 192
Query: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316
+ G I SMQ+VE+ G +PP P D++IV +TSG+TG PKG M+ H
Sbjct: 193 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 252
Query: 317 NVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLL 376
N++A +G E++ D I +LPLAH+ E + + +G R+G+ L
Sbjct: 253 NLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPLTL 307
Query: 377 SD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKRKQ 423
SD D L PT+ VP +++R+Y + S Q +++ L + K
Sbjct: 308 SDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKL 367
Query: 424 AEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGY 483
+++ G + + + L F K++A LGG VRM+++G AP SP F+ C + +GY
Sbjct: 368 EQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGY 425
Query: 484 GQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGPNV 540
G TE T T D+T+G VGAPL C IKL D +E Y GEI + G N+
Sbjct: 426 GLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNI 485
Query: 541 FKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPE 596
GY K+ ++T E ++D +G W TGDIG++ P G L+IIDRKK + KL GEYV+
Sbjct: 486 SMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLG 545
Query: 597 KIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLK 656
K+E + I S +++++ VVP+ + + AQ++G+EGT+ D+C N ++
Sbjct: 546 KVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAME 605
Query: 657 KAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEE 716
IL+++ L FE + + + ++ + GL+T K KR ELR ++ K IE
Sbjct: 606 AEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIER 665
Query: 717 LY 718
+Y
Sbjct: 666 MY 667
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 305 bits (782), Expect = 7e-83
Identities = 199/602 (33%), Positives = 312/602 (51%), Gaps = 42/602 (6%)
Query: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Y+W++Y EV R GSGL K I +F + R EW+I C+ Y+ +V L
Sbjct: 123 YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
Query: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259
Y TLG A+ + +N ++ S +I +V LLE + + +K II +D +A+
Sbjct: 181 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 233
Query: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316
+ G I SMQ+VE+ G +PP P D++IV +TSG+TG PKG M+ H
Sbjct: 234 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 293
Query: 317 NVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLL 376
N++A +G E++ D I +LPLAH+ E + + +G R+G+ L
Sbjct: 294 NLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPLTL 348
Query: 377 SD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKRKQ 423
SD D L PT+ VP +++R+Y + S Q +++ L + K
Sbjct: 349 SDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKL 408
Query: 424 AEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGY 483
+++ G + + + L F K++A LGG VRM+++G AP SP F+ C + +GY
Sbjct: 409 EQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGY 466
Query: 484 GQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGPNV 540
G TE T T D+T+G VGAPL C IKL D +E Y GEI + G N+
Sbjct: 467 GLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNI 526
Query: 541 FKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPE 596
GY K+ ++T E ++D +G W TGDIG++ P G L+IIDRKK + KL GEYV+
Sbjct: 527 SMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLG 586
Query: 597 KIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLK 656
K+E + I S +++++ VVP+ + + AQ++G+EGT+ D+C N ++
Sbjct: 587 KVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAME 646
Query: 657 KAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEE 716
IL+++ L FE + + + ++ + GL+T K KR ELR ++ K IE
Sbjct: 647 AEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIER 706
Query: 717 LY 718
+Y
Sbjct: 707 MY 708
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 159 bits (403), Expect = 7e-39
Identities = 162/638 (25%), Positives = 282/638 (44%), Gaps = 57/638 (8%)
Query: 116 TMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFI 175
T++++F L G+ LGF++ + ++ +SY + A G L+ K +
Sbjct: 104 TVHRMFYEALDKYGDLIALGFKR-QDKWEHISYSQYYLLARRAAKGFLKLGLKQAHS--V 160
Query: 176 GVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLL 235
+ N PEW + +V +Y T P A +YI + ++VD ++ +L
Sbjct: 161 AILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKIL 220
Query: 236 EHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ-PDD 294
+ K+ P LK +++ ++E + + + M+ + +E A + Q P+
Sbjct: 221 KIW--KQLPHLKAVVI---YKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQ 275
Query: 295 LSIVCFTSGTTGNPKGAMLTHGNVV-----ADFSGFLKVTEKVIFPRQDDVLISFLPLAH 349
++ +TSGTTGNPKG ML+ N+ +G ++ E Q +V++S+LPL+H
Sbjct: 276 CCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEV-----QQEVVVSYLPLSH 330
Query: 350 MFERVIQSVVYCH-GGRVGFFQGDIRL--LSDDMKALCPTIFPVVPRLLNRMYDKIFSQA 406
+ ++ G +V F + D L + ++ + PT VPR+ ++ ++I A
Sbjct: 331 IAAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVA 390
Query: 407 ------NTPLKRWLLEFAAKRKQAEVRSGIIR-NDSIWDELFFNKIQASLG--GCVRMIV 457
+ W + ++ S + + D L K++ +LG C +
Sbjct: 391 AQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFY 450
Query: 458 TGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLV 517
GAAP F L ++Y GYG +E + ++P ++ G +P +KLV
Sbjct: 451 -GAAPMMAETQHFF-LGLNIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLV 508
Query: 518 DVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKI 577
+ + +G GEIC+ G +F GYL D+T EA+D +GWLHTGD G+ G L I
Sbjct: 509 NQD------AEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYI 562
Query: 578 IDRKKHIFKLAQGEYVAPEKIENIYIRSQP-VAQIYVHGDSLKAFLVGIVV-----PD-- 629
R K + A GE V P IE P ++ + GD K + + + PD
Sbjct: 563 TGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTS 622
Query: 630 ------PEVMPSWAQKRGIEG-TYADLCTNKD--LKKAILEDMVRLGKESGLHSFEQVKA 680
E + Q+ G T +++ KD + +AI E + R+ + + K
Sbjct: 623 DQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKW 682
Query: 681 IHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
+ D FS+ G L PT+K KR + E +K I+ Y
Sbjct: 683 AILERD-FSISGGELGPTMKLKRLTVLEKYKGIIDSFY 719
>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
Length = 666
Score = 141 bits (356), Expect = 2e-33
Identities = 154/643 (23%), Positives = 292/643 (45%), Gaps = 59/643 (9%)
Query: 111 YDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKAC 170
++ T+ + FR ++ G P L + K+ ++ L++ + + L+ K
Sbjct: 47 HETPMTIPEFFRESVNRFGTYPALASKNGKK-WEILNFNQYYEACRKAAKSLI----KLG 101
Query: 171 TDQF--IGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKP 228
++F +G+ N EW I + + V +Y T +Y+I A ++ ++V+
Sbjct: 102 LERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVEND 161
Query: 229 QKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQ--KCGVVIKSMQAVEDCGQENHQA 286
Q+ +L + P LK II + +K+ ++ +++ D E Q
Sbjct: 162 QQLQKILSIPQSSLEP-LKAII---QYRLPMKKNNNLYSWDDFMELGRSIPDTQLE--QV 215
Query: 287 PVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLP 346
+ + +++ +TSGTTG PKG ML+H N+ VT+ + + ++S+LP
Sbjct: 216 IESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGA---VTKDFKLTDKHETVVSYLP 272
Query: 347 LAHMFERVIQSVVYCHGGRVGFF-QGDIR--LLSDDMKALCPTIFPVVPRLLNRMYDKIF 403
L+H+ +++ V G + +F Q D L +K + PT+F VP++ ++++ +
Sbjct: 273 LSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVK 332
Query: 404 --SQANTPLKR----WL--LEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLG-GCVR 454
S + LK+ W + F K+ + + + L F+K++ SLG
Sbjct: 333 KNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCH 392
Query: 455 MIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHI 514
++G AP + F +L + E YG +E + T + ++ L C I
Sbjct: 393 SFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNYRL------LSCGKI 445
Query: 515 KLVDVEELNYWACK-GEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAG 573
L + + + K G GEIC+ G ++F GYL+ T EA+D +GWLH+GD+G+ G
Sbjct: 446 -LTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLG 504
Query: 574 TLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQP-VAQIYVHGDSLKAFLVGIVVPDPEV 632
L + K I A GE V P +E + + P ++ + GD LK FL ++ E+
Sbjct: 505 FLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLK-FLSMLLTLKCEM 563
Query: 633 MPSWAQK------------RGI---EGTYADLCTNKD--LKKAILEDMVRLGKESGLHSF 675
+ RG+ T ++ +D + KAI + + + +E+ +++
Sbjct: 564 NQMSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVYKAIQQGINAVNQEA-MNNA 622
Query: 676 EQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
++++ I FS+ G L P +K KR + + +KKQI+ +Y
Sbjct: 623 QRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 87.8 bits (216), Expect = 3e-17
Identities = 110/444 (24%), Positives = 172/444 (38%), Gaps = 104/444 (23%)
Query: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214
L Q C+ C ++ + N +++ + A + V VPLY + Y+
Sbjct: 78 LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137
Query: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274
I + S V+ Q+ + LL V RK G+ L+ P A+ G V
Sbjct: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179
Query: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKV 332
+E + PVP Q + +++ +TSGTTG PKG + TH N+ A +G +
Sbjct: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWT 233
Query: 333 IFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385
+DDV++ LPL H+ V + G + + LS + +
Sbjct: 234 ----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287
Query: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442
+F VP + ++ YD+ F+Q P + L + K
Sbjct: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324
Query: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501
+R++V+G+A VL + G + E YG TE + T
Sbjct: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
Query: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541
G VG PLP +++V E AC + EGE+ VRGP+VF
Sbjct: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433
Query: 542 KGYLKDPDRTKEALDSDGWLHTGD 565
+ Y P+ TK A DGW TGD
Sbjct: 434 REYWNKPEETKSAFTLDGWFKTGD 457
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 87.8 bits (216), Expect = 3e-17
Identities = 110/444 (24%), Positives = 172/444 (38%), Gaps = 104/444 (23%)
Query: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214
L Q C+ C ++ + N +++ + A + V VPLY + Y+
Sbjct: 78 LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137
Query: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274
I + S V+ Q+ + LL V RK G+ L+ P A+ G V
Sbjct: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179
Query: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKV 332
+E + PVP Q + +++ +TSGTTG PKG + TH N+ A +G +
Sbjct: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWT 233
Query: 333 IFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385
+DDV++ LPL H+ V + G + + LS + +
Sbjct: 234 ----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287
Query: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442
+F VP + ++ YD+ F+Q P + L + K
Sbjct: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324
Query: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501
+R++V+G+A VL + G + E YG TE + T
Sbjct: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
Query: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541
G VG PLP +++V E AC + EGE+ VRGP+VF
Sbjct: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433
Query: 542 KGYLKDPDRTKEALDSDGWLHTGD 565
+ Y P+ TK A DGW TGD
Sbjct: 434 REYWNKPEETKSAFTLDGWFKTGD 457
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 79.7 bits (195), Expect = 9e-15
Identities = 111/488 (22%), Positives = 191/488 (39%), Gaps = 63/488 (12%)
Query: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205
L++ ++ + + SGLL + C +G++ N W++++LA +++V +
Sbjct: 100 LTFAQLKEEVDKAASGLL--SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
Query: 206 LGPGAIRYIINTADISTVIVDKPQKA-----VL--LLEHVERKETPGLKLIILMDPFEEA 258
+ Y++ ++ K K VL + VE + LK L D
Sbjct: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
Query: 259 LKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ----PDDLSIVCFTSGTTGNPKGAMLT 314
+ +++ + A Q Q Q D ++I FTSGTTG+PKGA L+
Sbjct: 218 SVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQ-FTSGTTGSPKGATLS 276
Query: 315 HGNVVAD---FSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQG 371
H N+V + LK+ EK P Q +++ PL H V +++ G
Sbjct: 277 HYNIVNNSNILGERLKLHEKT--PEQLRMILP-NPLYHCLGSVAGTMMCLMYGATLILAS 333
Query: 372 DIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGII 431
I + KAL + I + T L F Q + S
Sbjct: 334 PI---FNGKKAL----------------EAISRERGTFLYGTPTMFVDILNQPDFSS--- 371
Query: 432 RNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQ-VYEGYGQTECTA 490
I GG + +PA P ++ + + + + YG TE +
Sbjct: 372 -----------YDISTMCGGVI-----AGSPAPPELIRAIINKINMKDLVVAYGTTENSP 415
Query: 491 GCTFTTPGDWT---SGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKD 547
P D + VG +P +++++E GE+C+RG V GY +
Sbjct: 416 VTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGE 475
Query: 548 PDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQP 607
P +T+EA+D D W TGD+ G KI+ R K + + GE + P ++E+ +
Sbjct: 476 PQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHTHPK 534
Query: 608 VAQIYVHG 615
V ++ V G
Sbjct: 535 VQEVQVVG 542
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 59.7 bits (143), Expect = 9e-09
Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 15/179 (8%)
Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
VT P L RA G + E YGQTE C + G++G C +++
Sbjct: 335 VTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQI 394
Query: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571
+D ++ N EG+I +R +F GY+ +PD+T + D WL GD G
Sbjct: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDE 452
Query: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
G + + R I + G + P ++EN + V + V G+ +KAF+V
Sbjct: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510
Score = 32.0 bits (71), Expect = 2.1
Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)
Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
+++E+++ ++ + +L C + V PEW +V L C ++ +P
Sbjct: 82 NFRELSENSQ-QAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMP----- 135
Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
G I+ + + DI + KA++ + V ++ E P L++ +L+
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185
Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
+ C + + + + +H Q + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 59.7 bits (143), Expect = 9e-09
Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 15/179 (8%)
Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
+ G P L RA G + E YGQTE C + G++G C +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394
Query: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571
+D ++ N EG+I +R +F GY+++PD+T + D WL GD G
Sbjct: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDE 452
Query: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
G + + R I + G + P ++EN ++ V + V G+ +KAF++
Sbjct: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510
Score = 32.7 bits (73), Expect = 1.2
Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)
Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
+++E+++ ++ + +L C + V PEW +V L C ++ +P
Sbjct: 82 NFRELSENSQ-QAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135
Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
G I+ + + DI + KA++ + V ++ E P L++ +L+
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185
Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
+ C + + + + +H Q + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 59.7 bits (143), Expect = 9e-09
Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 15/179 (8%)
Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
+ G P L RA G + E YGQTE C + G++G C +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394
Query: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571
+D ++ N EG+I +R +F GY+++PD+T + D WL GD G
Sbjct: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDE 452
Query: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
G + + R I + G + P ++EN ++ V + V G+ +KAF++
Sbjct: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510
Score = 32.7 bits (73), Expect = 1.2
Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)
Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
+++E+++ ++ + +L C + V PEW +V L C ++ +P
Sbjct: 82 NFRELSENSQ-QAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135
Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
G I+ + + DI + KA++ + V ++ E P L++ +L+
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185
Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
+ C + + + + +H Q + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 58.5 bits (140), Expect = 2e-08
Identities = 56/201 (27%), Positives = 88/201 (43%), Gaps = 15/201 (7%)
Query: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494
+++ L N I + ++ V+ P +P V R G +YEGYGQTE C
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387
Query: 495 TTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRG-PN----VFKGYLKDPD 549
G +G P P +K+VDV N EG+I ++ PN +F Y+ +P
Sbjct: 388 FKGMKIKPGSMGKPSPAFDVKIVDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPS 446
Query: 550 RTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVA 609
+T L + ++ TGD G G + R + L+ G + P ++EN VA
Sbjct: 447 KTASTLRGNFYI-TGDRGYMDKDGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVA 504
Query: 610 QIYV-------HGDSLKAFLV 623
+ V G+ +KAF+V
Sbjct: 505 ESAVVSSPDPIRGEVVKAFVV 525
Score = 34.7 bits (78), Expect = 0.32
Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)
Query: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187
+KP P W + +E+ E LGS +L C + + PEW +
Sbjct: 76 KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135
Query: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246
+AC V++P L I Y + ++ + +I + + + V K E
Sbjct: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193
Query: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306
KLI+ E +E ++K C + H +++ + FTSGT+G
Sbjct: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240
Query: 307 NPKGAMLTHGN 317
PK TH +
Sbjct: 241 YPKMTAHTHSS 251
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 57.8 bits (138), Expect = 4e-08
Identities = 50/183 (27%), Positives = 82/183 (44%), Gaps = 15/183 (8%)
Query: 453 VRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCN 512
+R +TG P +P VL R G ++YEGYGQTE C + G +G +
Sbjct: 340 LRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPY 399
Query: 513 HIKLVDVEELNYWACKGEGEICVR-GPN----VFKGYLKDPDRTKEALDSDGWLHTGDIG 567
++++D E N EGEI +R P F Y+ +P +T + D ++ TGD G
Sbjct: 400 DVQIID-ENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYV-TGDRG 457
Query: 568 KWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQI-------YVHGDSLKA 620
G + R + ++ G + P ++E+ I V + + G+ +KA
Sbjct: 458 VMDSDGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKA 516
Query: 621 FLV 623
F+V
Sbjct: 517 FVV 519
Score = 33.1 bits (74), Expect = 0.93
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 20/152 (13%)
Query: 175 IGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDK---PQKA 231
+ V PEW +V +AC ++ +P L I Y + + ++ + P
Sbjct: 117 LAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVE 176
Query: 232 VLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ 291
++LE P LK +L+ P Q + S Q + E H
Sbjct: 177 SIVLE------CPDLKTKLLVSP---------QSWNGWL-SFQELFQFASEEHSCVETGS 220
Query: 292 PDDLSIVCFTSGTTGNPKGAMLTHGNVVADFS 323
+ ++I FTSGTTG PK A + ++ F+
Sbjct: 221 QEPMTIY-FTSGTTGFPKMAQHSQSSLGIGFT 251
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 15/183 (8%)
Query: 453 VRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCN 512
+R +TG +P V + G ++YEGYGQ+E C SG +G P
Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399
Query: 513 HIKLVDVEELNYWACKGEGEICVR-GPN----VFKGYLKDPDRTKEALDSDGWLHTGDIG 567
+++VD +E N EG + VR P F YL +P++T + D ++ TGD
Sbjct: 400 DVQIVD-DEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYI-TGDRA 457
Query: 568 KWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYV-------HGDSLKA 620
+ G + R + + + P ++E+ V + V G+ +KA
Sbjct: 458 RMDKDGYFWFMGRNDDVIN-SSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKA 516
Query: 621 FLV 623
F+V
Sbjct: 517 FIV 519
Score = 37.0 bits (84), Expect = 0.064
Identities = 53/252 (21%), Positives = 100/252 (39%), Gaps = 43/252 (17%)
Query: 100 IGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWL---------SYQE 150
I G QL+ Y++ A + V+ R L +G+ P P + W+ S++E
Sbjct: 42 ISLGRQLVPEYFNFAHDVLDVWSR-LEEAGHRP------PNPAFWWVNGTGAEIKWSFEE 94
Query: 151 VADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGA 210
+ ++ + +L C + + PEW +V +AC V++P L
Sbjct: 95 LGKQSR-KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKD 153
Query: 211 IRYIINTADISTVIVDKPQKAVLLLEHVE--RKETPGLKLIILMDPFEEALKERGQKCGV 268
++Y + + ++I L V+ E P L+ +L+ ++ +
Sbjct: 154 LKYRLQASRAKSIITSDS-----LAPRVDAISAECPSLQTKLLV---SDSSRPGWLNFRE 205
Query: 269 VIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHG------NVVADF 322
+++ +C + + P+ + FTSGTTG PK M+ H VA
Sbjct: 206 LLREASTEHNCMRTKSRDPL--------AIYFTSGTTGAPK--MVEHSQSSYGLGFVASG 255
Query: 323 SGFLKVTEKVIF 334
++ +TE IF
Sbjct: 256 RRWVALTESDIF 267
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 46.6 bits (109), Expect = 8e-05
Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 15/176 (8%)
Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
+ G P L RA G + E YGQTE C + G++G C +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394
Query: 517 VDVEELNYWACKGEGEICVRGPNV--FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGT 574
+ + A G++ G F G+ ++PD+T + D WL GD G G
Sbjct: 395 IAFVHGSPRA----GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGY 449
Query: 575 LKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
+ + R I + G + P ++EN ++ V + V G+ +KAF++
Sbjct: 450 FQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)
Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
+++E+++ ++ + +L C + V PEW +V L C ++ +P
Sbjct: 82 NFRELSENSQ-QAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135
Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
G I+ + + DI + KA++ + V ++ E P L++ +L+
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185
Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
+ C + + + + +H Q + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 46.6 bits (109), Expect = 8e-05
Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 15/176 (8%)
Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516
+ G P L RA G + E YGQTE C + G++G C +++
Sbjct: 335 LAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394
Query: 517 VDVEELNYWACKGEGEICVRGPNV--FKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGT 574
+ + A G++ G F G+ ++PD+T + D WL GD G G
Sbjct: 395 IAFVHGSPRA----GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGY 449
Query: 575 LKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623
+ + R I + G + P ++EN ++ V + V G+ +KAF++
Sbjct: 450 FQFMGRADDIIN-SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)
Query: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206
+++E+++ ++ + +L C + V PEW +V L C ++ +P
Sbjct: 82 NFRELSENSQ-QAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMP----- 135
Query: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260
G I+ + + DI + KA++ + V ++ E P L++ +L+
Sbjct: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185
Query: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311
+ C + + + + +H Q + S + FTSGT+G PK A
Sbjct: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 15/160 (9%)
Query: 476 GCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEI-- 533
G +YE YGQ+E C G +G P ++++D ++ + EG I
Sbjct: 360 GLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVID-DKGSILPPNTEGNIGI 418
Query: 534 ---CVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQG 590
VR ++F Y DP++T + ++ + +TGD GK G + + R I A G
Sbjct: 419 RIKPVRPVSLFMCYEGDPEKTAK-VECGDFYNTGDRGKMDEEGYICFLGRSDDIIN-ASG 476
Query: 591 EYVAPEKIENIYIRSQPVAQIYV-------HGDSLKAFLV 623
+ P ++E+ + VA+ V G+ +KAF+V
Sbjct: 477 YRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIV 516
Score = 37.4 bits (85), Expect = 0.049
Identities = 41/192 (21%), Positives = 72/192 (37%), Gaps = 26/192 (13%)
Query: 135 GFRKPKQPYQWL---------SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEW 185
G R P + W+ S++E+ D + + Q C + + PEW
Sbjct: 66 GKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQ-TCGLQQGDHLALMLPRVPEW 124
Query: 186 IIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVI-VDKPQKAVLLLEHVERKETP 244
+V + C ++ +P L I Y + + ++ +D V + + P
Sbjct: 125 WLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDSIA----SQCP 180
Query: 245 GLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGT 304
LK +L+ +E ++KS C + P+ ++ FTSGT
Sbjct: 181 SLKTKLLVSDHS---REGWLDFRSLVKSASPEHTCVKSKTLDPM--------VIFFTSGT 229
Query: 305 TGNPKGAMLTHG 316
TG PK A +HG
Sbjct: 230 TGFPKMAKHSHG 241
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 41.6 bits (96), Expect = 0.003
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 2/105 (1%)
Query: 433 NDSIWDELFFNKIQASLG-GCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAG 491
N ++ EL +K S ++ V P SP V+ + +YEGYGQTE
Sbjct: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376
Query: 492 CTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVR 536
C + +G PLP +++VD E N EG I +R
Sbjct: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 40.0 bits (92), Expect = 0.008
Identities = 29/79 (36%), Positives = 40/79 (50%), Gaps = 14/79 (17%)
Query: 286 APVPPQPDDL---------SIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPR 336
AP P P DL ++ +TSGTTG PK A+LTH V+ S L ++
Sbjct: 271 APSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLSGAT---- 325
Query: 337 QDDVLISFLPLAHMFERVI 355
DDV+ + LPL H+ V+
Sbjct: 326 ADDVVYTVLPLYHVMGLVV 344
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 38.5 bits (88), Expect = 0.022
Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 289 PPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLA 348
P D + FTSGTTG PK A ++H ++ GF ++ Q+DV+ LPL
Sbjct: 323 PQSITDTCLYIFTSGTTGLPKAARISHLKIL-QCQGFYQLCG----VHQEDVIYLALPLY 377
Query: 349 HMFERVIQSVVYCHG 363
HM ++ +V C G
Sbjct: 378 HMSGSLL-GIVGCMG 391
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 35.8 bits (81), Expect = 0.14
Identities = 23/82 (28%), Positives = 35/82 (42%)
Query: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494
+++ L N I + ++ V+ P +P V R G +YEGYGQTE C
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387
Query: 495 TTPGDWTSGHVGAPLPCNHIKL 516
G +G P P +K+
Sbjct: 388 FKGMKIKPGSMGKPSPAFDVKV 409
Score = 34.7 bits (78), Expect = 0.32
Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)
Query: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187
+KP P W + +E+ E LGS +L C + + PEW +
Sbjct: 76 KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135
Query: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246
+AC V++P L I Y + ++ + +I + + + V K E
Sbjct: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193
Query: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306
KLI+ E +E ++K C + H +++ + FTSGT+G
Sbjct: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240
Query: 307 NPKGAMLTHGN 317
PK TH +
Sbjct: 241 YPKMTAHTHSS 251
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 34.7 bits (78), Expect = 0.32
Identities = 64/280 (22%), Positives = 107/280 (38%), Gaps = 43/280 (15%)
Query: 145 WLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQ---NRPEWIIVELACYTYSMVVVP 201
+ +Y+ V + A L + LL H C + IG++ Q + P WI L VP
Sbjct: 32 YYTYKTVVNAASELSNFLLLH-CDFQGIREIGLYCQPGIDLPSWI---LGILQVPAAYVP 87
Query: 202 LYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEH----------VERKETPGLKL--- 248
+ P + + ++ ++V+K Q H VE + +L
Sbjct: 88 IEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWK 147
Query: 249 -----IILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSG 303
++L D E+ KE+ + I S E+ +E+ + L+ V TSG
Sbjct: 148 NTEVNLMLNDGKEKYEKEKIKS----ISSEHVNEEKAEEHMDLRLK---HCLAYVLHTSG 200
Query: 304 TTGNPKGAMLTHGNVVADFSGFLKVTEKVIFP-RQDDVLISFLPLAHMFERVIQSVVYCH 362
TTG PK + H +V + F +V+F Q+DVL PL V +
Sbjct: 201 TTGIPKIVRVPHKCIVPNIQHF-----RVLFDITQEDVLFLASPLTFDPSVVEIFLALSS 255
Query: 363 GGRVGFFQGDIRLLSDDMKALC-----PTIFPVVPRLLNR 397
G + ++LL + ++ T+ P LL R
Sbjct: 256 GASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRR 295
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 33.1 bits (74), Expect = 0.93
Identities = 33/117 (28%), Positives = 44/117 (37%), Gaps = 9/117 (7%)
Query: 300 FTSGTTGNPKGAMLTHGNVVADFS----GFLKVTEKVIFPRQDDVLISFLPLAHMFERVI 355
F+S G+ G GN A F+ G L EKV +D L S+L H E
Sbjct: 45 FSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEAN 104
Query: 356 QSVVY-CHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLK 411
+ G F G R L D FP++ L N++ S AN L+
Sbjct: 105 ADLEQKIKGWYEKFGPGSCRGLDHDYS----RYFPIIDDLKNQIIASTTSNANAVLQ 157
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,860,308
Number of Sequences: 37866
Number of extensions: 1359046
Number of successful extensions: 2637
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2523
Number of HSP's gapped (non-prelim): 62
length of query: 722
length of database: 18,247,518
effective HSP length: 110
effective length of query: 612
effective length of database: 14,082,258
effective search space: 8618341896
effective search space used: 8618341896
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.