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Search of human proteins with 56682953
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56682953 epidermal growth factor receptor pathway substrate
8 [Homo sapiens]
(822 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56682953 epidermal growth factor receptor pathway substrate 8... 1662 0.0
gi|21264616 epidermal growth factor receptor pathway substrate 8... 565 e-161
gi|148539853 epidermal growth factor receptor pathway substrate ... 463 e-130
gi|148539855 epidermal growth factor receptor pathway substrate ... 345 1e-94
gi|21071016 epidermal growth factor receptor pathway substrate 8... 260 4e-69
gi|21071018 epidermal growth factor receptor pathway substrate 8... 259 5e-69
gi|21071014 epidermal growth factor receptor pathway substrate 8... 218 2e-56
gi|5453754 NCK adaptor protein 1 [Homo sapiens] 57 7e-08
gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens] 57 9e-08
gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens] 57 9e-08
gi|52630427 NCK adaptor protein 2 isoform B [Homo sapiens] 55 2e-07
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 50 7e-06
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik... 50 1e-05
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 50 1e-05
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 50 1e-05
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r... 49 2e-05
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r... 47 9e-05
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r... 47 9e-05
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r... 47 9e-05
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 47 9e-05
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 46 2e-04
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 46 2e-04
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 46 2e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 46 2e-04
gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] 46 2e-04
gi|149944526 additional sex combs like 3 [Homo sapiens] 46 2e-04
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 45 3e-04
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 45 3e-04
gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 45 3e-04
gi|41327712 v-crk sarcoma virus CT10 oncogene homolog isoform a ... 45 4e-04
>gi|56682953 epidermal growth factor receptor pathway substrate 8
[Homo sapiens]
Length = 822
Score = 1662 bits (4305), Expect = 0.0
Identities = 822/822 (100%), Positives = 822/822 (100%)
Query: 1 MNGHISNHPSSFGMYPSQMNGYGSSPTFSQTDREHGSKTSAKALYEQRKNYARDSVSSVS 60
MNGHISNHPSSFGMYPSQMNGYGSSPTFSQTDREHGSKTSAKALYEQRKNYARDSVSSVS
Sbjct: 1 MNGHISNHPSSFGMYPSQMNGYGSSPTFSQTDREHGSKTSAKALYEQRKNYARDSVSSVS 60
Query: 61 DISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLE 120
DISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLE
Sbjct: 61 DISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLE 120
Query: 121 SKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEPTQNKPDLHLFQCDEVKANLISEDI 180
SKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEPTQNKPDLHLFQCDEVKANLISEDI
Sbjct: 121 SKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEPTQNKPDLHLFQCDEVKANLISEDI 180
Query: 181 ESAISDSKGGKQKRRPDALRMISNADPSIPPPPRAPAPAPPGTVTQVDVRSRVAAWSAWA 240
ESAISDSKGGKQKRRPDALRMISNADPSIPPPPRAPAPAPPGTVTQVDVRSRVAAWSAWA
Sbjct: 181 ESAISDSKGGKQKRRPDALRMISNADPSIPPPPRAPAPAPPGTVTQVDVRSRVAAWSAWA 240
Query: 241 ADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKR 300
ADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKR
Sbjct: 241 ADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKR 300
Query: 301 KKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHF 360
KKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHF
Sbjct: 301 KKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHF 360
Query: 361 LFTPLNMVVQATGGPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEW 420
LFTPLNMVVQATGGPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEW
Sbjct: 361 LFTPLNMVVQATGGPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEW 420
Query: 421 PKEQFIPPYVPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHS 480
PKEQFIPPYVPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHS
Sbjct: 421 PKEQFIPPYVPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHS 480
Query: 481 SVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKY 540
SVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKY
Sbjct: 481 SVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKY 540
Query: 541 DFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADP 600
DFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADP
Sbjct: 541 DFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADP 600
Query: 601 PYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSS 660
PYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSS
Sbjct: 601 PYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSS 660
Query: 661 SSDSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVIN 720
SSDSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVIN
Sbjct: 661 SSDSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVIN 720
Query: 721 ITYDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVYSQITVQ 780
ITYDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVYSQITVQ
Sbjct: 721 ITYDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVYSQITVQ 780
Query: 781 KAALEDSSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH 822
KAALEDSSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH
Sbjct: 781 KAALEDSSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH 822
>gi|21264616 epidermal growth factor receptor pathway substrate
8-like protein 2 [Homo sapiens]
Length = 715
Score = 565 bits (1456), Expect = e-161
Identities = 331/783 (42%), Positives = 452/783 (57%), Gaps = 100/783 (12%)
Query: 37 SKTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDA 96
+K S K L+EQRK Y+ +V + + SQY V+HL TF++D+ +A+ +VDD IRKL L +
Sbjct: 25 AKMSPKDLFEQRKKYSNSNVI-MHETSQYHVQHLATFIMDKSEAITSVDDAIRKLVQLSS 83
Query: 97 KGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEP 156
K K+WTQ+M+LQV+D+++ L+D+ES+ ELE+FPL T+Q Q V++ Y SVL LVC++
Sbjct: 84 KEKIWTQEMLLQVNDQSLRLLDIESQEELEDFPLPTVQRSQTVLNQLRYPSVLLLVCQDS 143
Query: 157 TQNKPDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPDALRMISNA---DPSIPPPP 213
Q+KPD+H F CDEV+A L+ EDIESA++D + GK K RP L+ SI PPP
Sbjct: 144 EQSKPDVHFFHCDEVEAELVHEDIESALADCRLGK-KMRPQTLKGHQEKIRQRQSILPPP 202
Query: 214 RAPAPAP--PGTVTQVDVRSRVAAWSAWAADQGDFEKP--RQYHEQEETPEMMAARIDRD 269
+ PAP P + ++RV Q +P R+ QEE ++A +I+++
Sbjct: 203 QGPAPIPFQHRGGDSPEAKNRVGP-------QVPLSEPGFRRRESQEEPRAVLAQKIEKE 255
Query: 270 VQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGEGVLTLRAKPPPPDEFL 329
QILN LDDIE+F+ +LQKAAEAF +L++RKK KK +K P EGVLTLRA+PP EF+
Sbjct: 256 TQILNCALDDIEWFVARLQKAAEAFKQLNQRKKGKKKGKKAPAEGVLTLRARPPSEGEFI 315
Query: 330 DCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGGPELASSVLSPLLNKD 389
DCFQK K NLLAKL+ HIQNPSAA+LVHFLF PL+++V GP++A SV PLL++D
Sbjct: 316 DCFQKIKLAINLLAKLQKHIQNPSAAELVHFLFGPLDLIVNTCSGPDIARSVSCPLLSRD 375
Query: 390 TIDFLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPYVPRFRNGWEPPMLNFMGATM 449
+DFL + E LW SLG +WM+ R+EWP+E +P YVP+F +GWEPP+ A
Sbjct: 376 AVDFLRGHLVPKEMSLWESLGESWMRPRSEWPREPQVPLYVPKFHSGWEPPVDVLQEAPW 435
Query: 450 EQDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGEA 509
E + LA + +Q I R S +HS SE P
Sbjct: 436 EVE--GLASAPIEEVSPVSRQSI-RNSQKHSPTSEPTPPGD------------------- 473
Query: 510 AVAFKPTSNRHIDRNYEPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWK 569
A P S+ H R Y+P KY K YDF ARN +ELSVLKD++LE+L+D +QWWK
Sbjct: 474 --ALPPVSSPHTHRGYQPTPAM-AKYVKILYDFTARNANELSVLKDEVLEVLEDGRQWWK 530
Query: 570 VRNASGDSGFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPT 629
+R+ SG +G+VP NIL RP ++G P+ QK +G
Sbjct: 531 LRSRSGQAGYVPCNILGEARPEDAG-----APFEQAGQKY---WG--------------- 567
Query: 630 PAPVPVPLPPSTPAPVPVSKVPANITRQNSSSSDSGGSIVRDSQRHKQLPVDRRKSQMEE 689
PA LPPS P D M+E
Sbjct: 568 PASPTHKLPPSFPG-----------------------------------NKDELMQHMDE 592
Query: 690 VQDELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDVKTWLQSKGFNPVTVNSLGV 749
V DELI +++ R+ Q+ F V R +TY+S P++V+ WL++K F+P V +LG+
Sbjct: 593 VNDELIRKISNIRAQPQRHFRVERSQPVSQPLTYESGPDEVRAWLEAKAFSPRIVENLGI 652
Query: 750 LNGAQLFSLNKDELRTVC-PEGARVYSQITVQKAALEDSSGSSELQEIMRRRQEKISAAA 808
L G QLFSLNK+EL+ VC EG RVYSQ+T+QKA LE SEL+E+M +
Sbjct: 653 LTGPQLFSLNKEELKKVCGEEGVRVYSQLTMQKAFLEKQQSGSELEELMNKFHSMNQRRG 712
Query: 809 SDS 811
DS
Sbjct: 713 EDS 715
>gi|148539853 epidermal growth factor receptor pathway substrate
8-like protein 1 isoform a [Homo sapiens]
Length = 723
Score = 463 bits (1191), Expect = e-130
Identities = 294/795 (36%), Positives = 428/795 (53%), Gaps = 106/795 (13%)
Query: 31 TDREHGSKTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRK 90
T E K SAK++YEQRK Y S ++D+SQY V HL TF L D + TV+D RK
Sbjct: 5 TGPEAAPKPSAKSIYEQRKRY---STVVMADVSQYPVNHLVTFCLGEDDGVHTVEDASRK 61
Query: 91 LKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLA 150
L ++D++G+VW Q+M+L+V V+L+D SK ELE++PL I C AVM S+L
Sbjct: 62 LAVMDSQGRVWAQEMLLRVSPDHVTLLDPASKEELESYPLGAIVRCDAVMPPGRSRSLLL 121
Query: 151 LVCKEPTQNKPDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPDALRMIS-----NA 205
LVC+EP + +PD+H FQ + A LI EDI+ A+ + + G+ +RR ALR +
Sbjct: 122 LVCQEPERAQPDVHFFQGLRLGAELIREDIQGALHNYRSGRGERRAAALRATQEELQRDR 181
Query: 206 DPSIPPPPRAPAPAPPGTVTQVDV---RSRVAAWSAWAADQGDFEKPRQYHEQEET---- 258
P+ PP P+ ++ V+ R R A A++ +P ++
Sbjct: 182 SPAAETPPLQRRPSVRAVISTVERGAGRGRPQAKPIPEAEEAQRPEPVGTSSNADSASPD 241
Query: 259 -----PEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGE 313
P++ + +R+V ILNH+ DD+E F+++LQK+AEA L R++ ++ +R+ GE
Sbjct: 242 LGPRGPDLAVLQAEREVDILNHVFDDVESFVSRLQKSAEAARVLEHRERGRRSRRRAAGE 301
Query: 314 GVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATG 373
G+LTLRAKPP E+ D QK K+ F+LLA+L+ +I +PS+ +L+HFLF PL M+V +G
Sbjct: 302 GLLTLRAKPPSEAEYTDVLQKIKYAFSLLARLRGNIADPSSPELLHFLFGPLQMIVNTSG 361
Query: 374 GPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPYVPRF 433
GPE ASSV P L D + L V E +LW SLG +W + E E+ PPY P F
Sbjct: 362 GPEFASSVRRPHLTSDAVALLRDNVTPRENELWTSLGDSWTRPGLELSPEEG-PPYRPEF 420
Query: 434 RNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAF 493
+GWEPP+ + E + V +H+R++
Sbjct: 421 FSGWEPPVTDPQSRAWE-------DPVEKQLQHERRR----------------------- 450
Query: 494 SSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEP-LKTQPK-KYAKSKYDFVARNNSELS 551
+ ++A +R ++ EP L+++ K+ YDF ARN+SELS
Sbjct: 451 ------------RQQSAPQVAVNGHRDLEPESEPQLESETAGKWVLCNYDFQARNSSELS 498
Query: 552 VLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADPPYTHTIQKQRM 611
V + D+LE+LDD ++WWKVR+ +G G+VP NIL PY R+
Sbjct: 499 VKQRDVLEVLDDSRKWWKVRDPAGQEGYVPYNIL--------------TPY----PGPRL 540
Query: 612 EYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSSSSDSGGSIVRD 671
+ PA + + +PPP PAP P P PP+ P R S DS +
Sbjct: 541 HHSQSPARSLNS-TPPPPPAPAPAP-PPALARP--------RWDRPRWDSCDSLNGLD-- 588
Query: 672 SQRHKQLPVDRRK-SQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDV 730
P ++ K SQM V +EL RL GRS + VP P ++ S +V
Sbjct: 589 -------PSEKEKFSQMLIVNEELQARLAQGRSGPSRA--VPGPRAPEPQLSPGSDASEV 639
Query: 731 KTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCP-EGARVYSQITVQKAALEDSSG 789
+ WLQ+KGF+ TV++LGVL GAQLFSL K+ELR V P EGARVYSQ+TVQ++ LED
Sbjct: 640 RAWLQAKGFSSGTVDALGVLTGAQLFSLQKEELRAVSPEEGARVYSQVTVQRSLLEDKEK 699
Query: 790 SSELQEIMRRRQEKI 804
SEL+ +M ++++K+
Sbjct: 700 VSELEAVMEKQKKKV 714
>gi|148539855 epidermal growth factor receptor pathway substrate
8-like protein 1 isoform b [Homo sapiens]
Length = 596
Score = 345 bits (885), Expect = 1e-94
Identities = 229/654 (35%), Positives = 339/654 (51%), Gaps = 103/654 (15%)
Query: 172 KANLISEDIESAISDSKGGKQKRRPDALRMIS-----NADPSIPPPPRAPAPAPPGTVTQ 226
+A LI EDI+ A+ + + G+ +RR ALR + P+ PP P+ ++
Sbjct: 16 EAELIREDIQGALHNYRSGRGERRAAALRATQEELQRDRSPAAETPPLQRRPSVRAVIST 75
Query: 227 VDV---RSRVAAWSAWAADQGDFEKPRQYHEQEET---------PEMMAARIDRDVQILN 274
V+ R R A A++ +P ++ P++ + +R+V ILN
Sbjct: 76 VERGAGRGRPQAKPIPEAEEAQRPEPVGTSSNADSASPDLGPRGPDLAVLQAEREVDILN 135
Query: 275 HILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQK 334
H+ DD+E F+++LQK+AEA L R++ ++ +R+ GEG+LTLRAKPP E+ D QK
Sbjct: 136 HVFDDVESFVSRLQKSAEAARVLEHRERGRRSRRRAAGEGLLTLRAKPPSEAEYTDVLQK 195
Query: 335 FKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGGPELASSVLSPLLNKDTIDFL 394
K+ F+LLA+L+ +I +PS+ +L+HFLF PL M+V +GGPE ASSV P L D + L
Sbjct: 196 IKYAFSLLARLRGNIADPSSPELLHFLFGPLQMIVNTSGGPEFASSVRRPHLTSDAVALL 255
Query: 395 NYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPYVPRFRNGWEPPMLNFMGATMEQDLY 454
V E +LW SLG +W + E E+ PPY P F +GWEPP+ + E
Sbjct: 256 RDNVTPRENELWTSLGDSWTRPGLELSPEEG-PPYRPEFFSGWEPPVTDPQSRAWE---- 310
Query: 455 QLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFK 514
+ V +H+R++ + ++A
Sbjct: 311 ---DPVEKQLQHERRR-----------------------------------RQQSAPQVA 332
Query: 515 PTSNRHIDRNYEP-LKTQPK-KYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRN 572
+R ++ EP L+++ K+ YDF ARN+SELSV + D+LE+LDD ++WWKVR+
Sbjct: 333 VNGHRDLEPESEPQLESETAGKWVLCNYDFQARNSSELSVKQRDVLEVLDDSRKWWKVRD 392
Query: 573 ASGDSGFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAP 632
+G G+VP NIL PY R+ + PA + + +PPP PAP
Sbjct: 393 PAGQEGYVPYNIL--------------TPY----PGPRLHHSQSPARSLNS-TPPPPPAP 433
Query: 633 VPVPLPPSTPAPVPVSKVPANITRQNSSSSDSGGSIVRDSQRHKQLPVDRRK-SQMEEVQ 691
P P PP+ P R S DS + P ++ K SQM V
Sbjct: 434 APAP-PPALARP--------RWDRPRWDSCDSLNGLD---------PSEKEKFSQMLIVN 475
Query: 692 DELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDVKTWLQSKGFNPVTVNSLGVLN 751
+EL RL GRS + VP P ++ S +V+ WLQ+KGF+ TV++LGVL
Sbjct: 476 EELQARLAQGRSGPSRA--VPGPRAPEPQLSPGSDASEVRAWLQAKGFSSGTVDALGVLT 533
Query: 752 GAQLFSLNKDELRTVCP-EGARVYSQITVQKAALEDSSGSSELQEIMRRRQEKI 804
GAQLFSL K+ELR V P EGARVYSQ+TVQ++ LED SEL+ +M ++++K+
Sbjct: 534 GAQLFSLQKEELRAVSPEEGARVYSQVTVQRSLLEDKEKVSELEAVMEKQKKKV 587
>gi|21071016 epidermal growth factor receptor pathway substrate
8-like protein 3 isoform b [Homo sapiens]
Length = 593
Score = 260 bits (664), Expect = 4e-69
Identities = 181/591 (30%), Positives = 280/591 (47%), Gaps = 100/591 (16%)
Query: 37 SKTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDA 96
S+ S++A+Y RK Y+++ ++S + Q+RVEHL T + +D ++KL +DA
Sbjct: 2 SRPSSRAIYLHRKEYSQN-LTSEPTLLQHRVEHLMT-CKQGSQRVQGPEDALQKLFEMDA 59
Query: 97 KGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEP 156
+G+VW+QD+ILQV D + L+D+E+K EL+++ L++IQ +++CSY+S+L++ +EP
Sbjct: 60 QGRVWSQDLILQVRDGWLQLLDIETKEELDSYRLDSIQAMNVALNTCSYNSILSITVQEP 119
Query: 157 TQNKPDLHLFQCDEVKANLISEDIESAISDSK------GGKQK----------RRPDALR 200
LFQC EV A + ++ A+ + GG Q RP +
Sbjct: 120 GLPGTSTLLFQCQEVGAERLKTSLQKALEEELEQRPRLGGLQPGQDRWRGPAMERPLPME 179
Query: 201 MISNADPSIPPP-----------PRAPAPAPPGTVTQVDVRSRVAAWSAWAADQGDFEKP 249
+P IPP P +P P P T SA P
Sbjct: 180 QARYLEPGIPPEQPHQRTLEHSLPPSPRPLPRHT-------------SAREPSAFTLPPP 226
Query: 250 RQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRK 309
R+ E+ +RD ++LNH+L DIE F+ KL+KA +K + KK +K
Sbjct: 227 RRSSSPEDP--------ERDEEVLNHVLRDIELFMGKLEKAQ------AKTSRKKKFGKK 272
Query: 310 GPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVV 369
+G LT +++DCFQK KH FNLL +L + ++ SA +LVH LF LN ++
Sbjct: 273 NKDQGGLTQA-------QYIDCFQKIKHSFNLLGRLATWLKETSAPELVHILFKSLNFIL 325
Query: 370 QATGGPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPY 429
LA+ V+SPLL I+ L ++ E LWM LG W +RA+W ++ + PY
Sbjct: 326 ARCPEAGLAAQVISPLLTPKAINLLQSCLSPPESNLWMGLGPAWTTSRADWTGDEPL-PY 384
Query: 430 VPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPAD 489
P F + W+ P + QD L R+ + ST H + H D
Sbjct: 385 QPTFSDDWQLPEPSSQAPLGYQDPVSL-----------RRGSHRLGSTSHFPQEKTHNHD 433
Query: 490 GYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKYDFVARNNSE 549
P R P QP + Y+F ARN E
Sbjct: 434 -------------------------PQPGDPNSRPSSPKPAQPALKMQVLYEFEARNPRE 468
Query: 550 LSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADP 600
L+V++ + LE+LD K+WW V+N +G SG++P+NIL+ ++P G P
Sbjct: 469 LTVVQGEKLEVLDHSKRWWLVKNEAGRSGYIPSNILEPLQPGTPGTQGQSP 519
Score = 51.6 bits (122), Expect = 3e-06
Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 16/183 (8%)
Query: 603 THTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSSSS 662
+H Q++ + P+P D PS P P P+ V + + A R+ +
Sbjct: 422 SHFPQEKTHNHDPQPGDPNSRPSSPK-------PAQPALKMQV-LYEFEARNPRELTVVQ 473
Query: 663 DSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINIT 722
++ S+R + + +S + ++ L G Q + VP++ ++
Sbjct: 474 GEKLEVLDHSKRWWLVKNEAGRSGY--IPSNILEPLQPGTPGTQGQ---SPSRVPMLRLS 528
Query: 723 YDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCP-EGARVYSQITVQK 781
S PE+V WLQ++ F+ TV +LG L G+QL + EL+ +CP E R+ S++ +
Sbjct: 529 --SRPEEVTDWLQAENFSTATVRTLGSLTGSQLLRIRPGELQMLCPQEAPRILSRLEAVR 586
Query: 782 AAL 784
L
Sbjct: 587 RML 589
>gi|21071018 epidermal growth factor receptor pathway substrate
8-like protein 3 isoform a [Homo sapiens]
Length = 594
Score = 259 bits (663), Expect = 5e-69
Identities = 181/592 (30%), Positives = 280/592 (47%), Gaps = 101/592 (17%)
Query: 37 SKTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDA 96
S+ S++A+Y RK Y+++ ++S + Q+RVEHL T + +D ++KL +DA
Sbjct: 2 SRPSSRAIYLHRKEYSQN-LTSEPTLLQHRVEHLMT-CKQGSQRVQGPEDALQKLFEMDA 59
Query: 97 KGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEP 156
+G+VW+QD+ILQV D + L+D+E+K EL+++ L++IQ +++CSY+S+L++ +EP
Sbjct: 60 QGRVWSQDLILQVRDGWLQLLDIETKEELDSYRLDSIQAMNVALNTCSYNSILSITVQEP 119
Query: 157 TQNKPDLHLFQCDEVKANLISEDIESAISDSK-------GGKQK----------RRPDAL 199
LFQC EV A + ++ A+ + GG Q RP +
Sbjct: 120 GLPGTSTLLFQCQEVGAERLKTSLQKALEEELEQSRPRLGGLQPGQDRWRGPAMERPLPM 179
Query: 200 RMISNADPSIPPP-----------PRAPAPAPPGTVTQVDVRSRVAAWSAWAADQGDFEK 248
+P IPP P +P P P T SA
Sbjct: 180 EQARYLEPGIPPEQPHQRTLEHSLPPSPRPLPRHT-------------SAREPSAFTLPP 226
Query: 249 PRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKR 308
PR+ E+ +RD ++LNH+L DIE F+ KL+KA +K + KK +
Sbjct: 227 PRRSSSPEDP--------ERDEEVLNHVLRDIELFMGKLEKAQ------AKTSRKKKFGK 272
Query: 309 KGPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMV 368
K +G LT +++DCFQK KH FNLL +L + ++ SA +LVH LF LN +
Sbjct: 273 KNKDQGGLTQA-------QYIDCFQKIKHSFNLLGRLATWLKETSAPELVHILFKSLNFI 325
Query: 369 VQATGGPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPP 428
+ LA+ V+SPLL I+ L ++ E LWM LG W +RA+W ++ + P
Sbjct: 326 LARCPEAGLAAQVISPLLTPKAINLLQSCLSPPESNLWMGLGPAWTTSRADWTGDEPL-P 384
Query: 429 YVPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPA 488
Y P F + W+ P + QD L R+ + ST H + H
Sbjct: 385 YQPTFSDDWQLPEPSSQAPLGYQDPVSL-----------RRGSHRLGSTSHFPQEKTHNH 433
Query: 489 DGYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKYDFVARNNS 548
D P R P QP + Y+F ARN
Sbjct: 434 D-------------------------PQPGDPNSRPSSPKPAQPALKMQVLYEFEARNPR 468
Query: 549 ELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADP 600
EL+V++ + LE+LD K+WW V+N +G SG++P+NIL+ ++P G P
Sbjct: 469 ELTVVQGEKLEVLDHSKRWWLVKNEAGRSGYIPSNILEPLQPGTPGTQGQSP 520
Score = 51.6 bits (122), Expect = 3e-06
Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 16/183 (8%)
Query: 603 THTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSSSS 662
+H Q++ + P+P D PS P P P+ V + + A R+ +
Sbjct: 423 SHFPQEKTHNHDPQPGDPNSRPSSPK-------PAQPALKMQV-LYEFEARNPRELTVVQ 474
Query: 663 DSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINIT 722
++ S+R + + +S + ++ L G Q + VP++ ++
Sbjct: 475 GEKLEVLDHSKRWWLVKNEAGRSGY--IPSNILEPLQPGTPGTQGQ---SPSRVPMLRLS 529
Query: 723 YDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCP-EGARVYSQITVQK 781
S PE+V WLQ++ F+ TV +LG L G+QL + EL+ +CP E R+ S++ +
Sbjct: 530 --SRPEEVTDWLQAENFSTATVRTLGSLTGSQLLRIRPGELQMLCPQEAPRILSRLEAVR 587
Query: 782 AAL 784
L
Sbjct: 588 RML 590
>gi|21071014 epidermal growth factor receptor pathway substrate
8-like protein 3 isoform c [Homo sapiens]
Length = 563
Score = 218 bits (555), Expect = 2e-56
Identities = 146/463 (31%), Positives = 229/463 (49%), Gaps = 64/463 (13%)
Query: 37 SKTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDA 96
S+ S++A+Y RK Y+++ ++S + Q+RVEHL T + +D ++KL +DA
Sbjct: 2 SRPSSRAIYLHRKEYSQN-LTSEPTLLQHRVEHLMT-CKQGSQRVQGPEDALQKLFEMDA 59
Query: 97 KGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEP 156
+G+VW+QD+ILQV D + L+D+E+K EL+++ L++IQ +++CSY+S+L++ +EP
Sbjct: 60 QGRVWSQDLILQVRDGWLQLLDIETKEELDSYRLDSIQAMNVALNTCSYNSILSITVQEP 119
Query: 157 TQNKPDLHLFQCDEVKANLISEDIESAISDSK------GGKQK----------RRPDALR 200
LFQC EV A + ++ A+ + GG Q RP +
Sbjct: 120 GLPGTSTLLFQCQEVGAERLKTSLQKALEEELEQRPRLGGLQPGQDRWRGPAMERPLPME 179
Query: 201 MISNADPSIPPP-----------PRAPAPAPPGTVTQVDVRSRVAAWSAWAADQGDFEKP 249
+P IPP P +P P P T SA P
Sbjct: 180 QARYLEPGIPPEQPHQRTLEHSLPPSPRPLPRHT-------------SAREPSAFTLPPP 226
Query: 250 RQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRK 309
R+ E+ +RD ++LNH+L DIE F+ KL+KA +K + KK +K
Sbjct: 227 RRSSSPEDP--------ERDEEVLNHVLRDIELFMGKLEKAQ------AKTSRKKKFGKK 272
Query: 310 GPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVV 369
+G LT +++DCFQK KH FNLL +L + ++ SA +LVH LF LN ++
Sbjct: 273 NKDQGGLTQA-------QYIDCFQKIKHSFNLLGRLATWLKETSAPELVHILFKSLNFIL 325
Query: 370 QATGGPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPY 429
LA+ V+SPLL I+ L ++ E LWM LG W +RA+W ++ + PY
Sbjct: 326 ARCPEAGLAAQVISPLLTPKAINLLQSCLSPPESNLWMGLGPAWTTSRADWTGDEPL-PY 384
Query: 430 VPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEI 472
P F + W+ P + QD L S A+ K ++
Sbjct: 385 QPTFSDDWQLPEPSSQAPLGYQDPVSLRPSSPKPAQPALKMQV 427
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/78 (39%), Positives = 47/78 (60%)
Query: 523 RNYEPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPN 582
R P QP + Y+F ARN EL+V++ + LE+LD K+WW V+N +G SG++P+
Sbjct: 412 RPSSPKPAQPALKMQVLYEFEARNPRELTVVQGEKLEVLDHSKRWWLVKNEAGRSGYIPS 471
Query: 583 NILDIVRPPESGLGRADP 600
NIL+ ++P G P
Sbjct: 472 NILEPLQPGTPGTQGQSP 489
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/220 (26%), Positives = 97/220 (44%), Gaps = 25/220 (11%)
Query: 582 NNILDIVRPPESGLGRADPPYTHTIQK-----QRMEYGPRPADTPPAPSPPPTPAPV--- 633
N + + PPES L P T + + + Y P +D P P + AP+
Sbjct: 348 NLLQSCLSPPESNLWMGLGPAWTTSRADWTGDEPLPYQPTFSDDWQLPEPS-SQAPLGYQ 406
Query: 634 -PVPLPPSTPAPV-PVSKVP------ANITRQNSSSSDSGGSIVRDSQRHKQLPVDRRKS 685
PV L PS+P P P K+ A R+ + ++ S+R + + +S
Sbjct: 407 DPVSLRPSSPKPAQPALKMQVLYEFEARNPRELTVVQGEKLEVLDHSKRWWLVKNEAGRS 466
Query: 686 QMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDVKTWLQSKGFNPVTVN 745
+ ++ L G Q + VP++ ++ S PE+V WLQ++ F+ TV
Sbjct: 467 GY--IPSNILEPLQPGTPGTQGQ---SPSRVPMLRLS--SRPEEVTDWLQAENFSTATVR 519
Query: 746 SLGVLNGAQLFSLNKDELRTVCP-EGARVYSQITVQKAAL 784
+LG L G+QL + EL+ +CP E R+ S++ + L
Sbjct: 520 TLGSLTGSQLLRIRPGELQMLCPQEAPRILSRLEAVRRML 559
>gi|5453754 NCK adaptor protein 1 [Homo sapiens]
Length = 377
Score = 57.0 bits (136), Expect = 7e-08
Identities = 22/49 (44%), Positives = 36/49 (73%)
Query: 538 SKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILD 586
+K+D+VA+ EL + K++ L +LDD K WW+VRN+ +GFVP+N ++
Sbjct: 9 AKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVE 57
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 5/66 (7%)
Query: 540 YDFVARNNSELSVLKDDILEILDDRK---QWWKVRNASGDSGFVPNNILDIVR--PPESG 594
Y F + N+ EL+ K D++++++ + +WWK R +G G VP N + +++ P SG
Sbjct: 199 YPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSG 258
Query: 595 LGRADP 600
L + P
Sbjct: 259 LEPSPP 264
>gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 56.6 bits (135), Expect = 9e-08
Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 538 SKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGR 597
+K+D+ A+ + EL + K++ L +LDD K WW+VRNA+ +G+VP+N ++ + G
Sbjct: 9 AKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLV 68
Query: 598 ADPPYTHTIQKQRMEYGPRPADTPPAPS 625
+ T + K R + R D P PS
Sbjct: 69 KNLKDTLGLGKTRRKTSAR--DASPTPS 94
Score = 38.1 bits (87), Expect = 0.033
Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 13/80 (16%)
Query: 540 YDFVARNNSELSVLKDDILEILDDRK---QWWKVRNASGDSGFVPNNILDIVRPPESGLG 596
Y F + EL+ K + +E+++ + +WWK +NA G G VP N + ++
Sbjct: 204 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVL-------- 255
Query: 597 RADPPYTHTIQKQRMEY-GP 615
+D P H ++ Y GP
Sbjct: 256 -SDGPALHPAHAPQISYTGP 274
>gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 56.6 bits (135), Expect = 9e-08
Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 538 SKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGR 597
+K+D+ A+ + EL + K++ L +LDD K WW+VRNA+ +G+VP+N ++ + G
Sbjct: 9 AKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLV 68
Query: 598 ADPPYTHTIQKQRMEYGPRPADTPPAPS 625
+ T + K R + R D P PS
Sbjct: 69 KNLKDTLGLGKTRRKTSAR--DASPTPS 94
Score = 38.1 bits (87), Expect = 0.033
Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 13/80 (16%)
Query: 540 YDFVARNNSELSVLKDDILEILDDRK---QWWKVRNASGDSGFVPNNILDIVRPPESGLG 596
Y F + EL+ K + +E+++ + +WWK +NA G G VP N + ++
Sbjct: 204 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVL-------- 255
Query: 597 RADPPYTHTIQKQRMEY-GP 615
+D P H ++ Y GP
Sbjct: 256 -SDGPALHPAHAPQISYTGP 274
>gi|52630427 NCK adaptor protein 2 isoform B [Homo sapiens]
Length = 83
Score = 55.5 bits (132), Expect = 2e-07
Identities = 21/49 (42%), Positives = 37/49 (75%)
Query: 538 SKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILD 586
+K+D+ A+ + EL + K++ L +LDD K WW+VRNA+ +G+VP+N ++
Sbjct: 9 AKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVE 57
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 50.4 bits (119), Expect = 7e-06
Identities = 42/121 (34%), Positives = 54/121 (44%), Gaps = 23/121 (19%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDRKQ----WWKVRNASGDSGFVPNNILDIVRPP 591
AK+ YD VA + ELS K DI+ +L+ Q WW + + G G VP N L I+
Sbjct: 8 AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWW-LCSLHGRQGIVPGNRLKIL--- 63
Query: 592 ESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSP----PPTPAPVPVPLPPSTPAPVPV 647
+G D K+ GP P TP P P P PA P+ P+T P P
Sbjct: 64 ---VGMYD--------KKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPD 112
Query: 648 S 648
S
Sbjct: 113 S 113
>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
[Homo sapiens]
Length = 303
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 3/114 (2%)
Query: 534 KYAKSKYDFVARNNSELSVLKDDILEILD-DRKQWWKVRNASGDSGFVPNNILD-IVRPP 591
+Y ++ YDF + +L K +IL I++ +QWW RN G G +P ++ +VR
Sbjct: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSS 185
Query: 592 ESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPV 645
G ++ I + Y +P T P P+ +P PLP + PV
Sbjct: 186 PHGKHGNRNSNSYGIPEPAHAYA-QPQTTTPLPAVSGSPGAAITPLPSTQNGPV 238
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/74 (37%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 615 PRPADTP-PAPSPPPTPAPVPVPLPPSTPAPVPV-SKVPANITRQNSSSSDSGGSIVRDS 672
PRP +P PAP+P P P+P P+P TPAP P + PA T SGG+
Sbjct: 16 PRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGD 75
Query: 673 QRHKQLPVDRRKSQ 686
L +R SQ
Sbjct: 76 PARPGLSQQQRASQ 89
Score = 46.2 bits (108), Expect = 1e-04
Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 2/74 (2%)
Query: 615 PRPADTP-PAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSSSSDSGGSIVRDSQ 673
P PA TP PAPSP P P P P P PA P S + SGG R
Sbjct: 22 PAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGL 81
Query: 674 RHKQLPVDRRKSQM 687
+Q +RK+Q+
Sbjct: 82 SQQQ-RASQRKAQV 94
Score = 32.0 bits (71), Expect = 2.4
Identities = 13/23 (56%), Positives = 14/23 (60%)
Query: 624 PSPPPTPAPVPVPLPPSTPAPVP 646
PS PTPAP P P +PAP P
Sbjct: 4 PSQAPTPAPAAQPRPLQSPAPAP 26
Score = 30.4 bits (67), Expect = 7.0
Identities = 11/25 (44%), Positives = 13/25 (52%)
Query: 622 PAPSPPPTPAPVPVPLPPSTPAPVP 646
P P+P P P+ P P TP P P
Sbjct: 8 PTPAPAAQPRPLQSPAPAPTPTPAP 32
Score = 30.0 bits (66), Expect = 9.1
Identities = 12/25 (48%), Positives = 14/25 (56%)
Query: 622 PAPSPPPTPAPVPVPLPPSTPAPVP 646
P+ +P P PA P PL PAP P
Sbjct: 4 PSQAPTPAPAAQPRPLQSPAPAPTP 28
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 573 ASGDSGFVPNNILDIVRPPESGL-GRADPPYTHTIQKQRMEYG------PRP-ADTPPAP 624
A G +G P + R P + G PP + + +G PRP PP P
Sbjct: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP 177
Query: 625 SPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQN 658
+PPP P P+P PLP S+P P+ P +T+ N
Sbjct: 178 TPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGN 211
Score = 35.4 bits (80), Expect = 0.22
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)
Query: 615 PRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPANITRQNSSSSDSGGSIVRDSQR 674
P P PP PPP P P P PPS P PVS +++ R + + + ++ R
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAP---PVSTDTSSLRRADPKGRSALLADIQQGTR 58
Query: 675 HKQLPV--DRRKSQME 688
+++ DR Q+E
Sbjct: 59 LRKVTQINDRSAPQIE 74
Score = 35.0 bits (79), Expect = 0.28
Identities = 14/29 (48%), Positives = 14/29 (48%)
Query: 614 GPRPADTPPAPSPPPTPAPVPVPLPPSTP 642
G P PP P PP P P P P PP P
Sbjct: 210 GNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
Score = 30.4 bits (67), Expect = 7.0
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 614 GPRPADTPPAPSPPPTPAPVPVP-LPPSTPAPVPVSKV 650
GP P +PP AP P P PP TP P+P + V
Sbjct: 205 GPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASV 242
>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 353
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/121 (33%), Positives = 54/121 (44%), Gaps = 23/121 (19%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDRKQ----WWKVRNASGDSGFVPNNILDIVRPP 591
AK+ YD VA + ELS K DI+ +L+ Q WW + + G G +P N L I+
Sbjct: 8 AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWW-LCSLHGRQGIMPGNHLKIL--- 63
Query: 592 ESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSP----PPTPAPVPVPLPPSTPAPVPV 647
+G D K+ GP P TP P P P PA P+ P+T P P
Sbjct: 64 ---VGMYD--------KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPD 112
Query: 648 S 648
S
Sbjct: 113 S 113
>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 232
Score = 46.6 bits (109), Expect = 9e-05
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDRKQ----WWKVRNASGDSGFVPNNILDIVRPP 591
AK+ Y VA + ELS K DI+ +L+ Q WW + + G G VP N L I+
Sbjct: 8 AKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWW-LCSLHGRQGIVPGNHLKIL--- 63
Query: 592 ESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSP----PPTPAPVPVPLPPSTPAPVPV 647
+G D K+ GP P TP P P P PA P+ P+T P P
Sbjct: 64 ---VGMYD--------KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPD 112
Query: 648 S 648
S
Sbjct: 113 S 113
>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 224
Score = 46.6 bits (109), Expect = 9e-05
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDRKQ----WWKVRNASGDSGFVPNNILDIVRPP 591
AK+ Y VA + ELS K DI+ +L+ Q WW + + G G VP N L I+
Sbjct: 8 AKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWW-LCSLHGRQGIVPGNHLKIL--- 63
Query: 592 ESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSP----PPTPAPVPVPLPPSTPAPVPV 647
+G D K+ GP P TP P P P PA P+ P+T P P
Sbjct: 64 ---VGMYD--------KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPD 112
Query: 648 S 648
S
Sbjct: 113 S 113
>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 368
Score = 46.6 bits (109), Expect = 9e-05
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDRKQ----WWKVRNASGDSGFVPNNILDIVRPP 591
AK+ Y VA + ELS K DI+ +L+ Q WW + + G G VP N L I+
Sbjct: 8 AKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWW-LCSLHGRQGIVPGNHLKIL--- 63
Query: 592 ESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSP----PPTPAPVPVPLPPSTPAPVPV 647
+G D K+ GP P TP P P P PA P+ P+T P P
Sbjct: 64 ---VGMYD--------KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPD 112
Query: 648 S 648
S
Sbjct: 113 S 113
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 46.6 bits (109), Expect = 9e-05
Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 14/80 (17%)
Query: 590 PPESGLGRADPPYTHTIQKQRMEY--------GPRP--ADTPPAPSPPPTPAPVPVPLPP 639
PP + PP++H + Y PRP A P PSPPP P P P PLPP
Sbjct: 238 PPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPP 297
Query: 640 STPAPVP----VSKVPANIT 655
P P P +K+P ++
Sbjct: 298 PPPPPPPTPSSTTKLPQGLS 317
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 597 RADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPV------SKV 650
+A P + + + + + R PPAP PP P+P P PP PA P+ +
Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 651 PANITRQNSSSSDS---GGSIVRDSQRHKQLPVD-RRKSQMEEVQDELIHRLTIGRSAAQ 706
PA T+ SSS + + PVD R SQME++++EL L R +
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
Query: 707 KKFHVPRQNV 716
H P V
Sbjct: 487 FLSHRPGPTV 496
Score = 37.4 bits (85), Expect = 0.057
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 590 PPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPP-----PTPAPVPVPLPPSTPAP 644
PP L PP HT+ + P P D P P+PP P P PVP P PP+ +P
Sbjct: 189 PPPPVLEALSPP--HTLSSPSI---PTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASP 242
Query: 645 VPVSK---VPANITRQNSSSSDSG 665
V P +T+ S + +G
Sbjct: 243 HTVGTRLFPPGGVTKWKSDVALNG 266
Score = 34.3 bits (77), Expect = 0.48
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 614 GPRPADTPPAPSPPPTPAPVPVPLPPS-TPAPVPV 647
G P +PP+ +PPP P + P PPS P P PV
Sbjct: 159 GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPV 193
Score = 30.0 bits (66), Expect = 9.1
Identities = 16/43 (37%), Positives = 18/43 (41%), Gaps = 8/43 (18%)
Query: 612 EYGPRPADTPPAPSPPP--------TPAPVPVPLPPSTPAPVP 646
+YG PP P P P P P+P PPST P P
Sbjct: 132 QYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPP 174
Score = 30.0 bits (66), Expect = 9.1
Identities = 11/21 (52%), Positives = 14/21 (66%)
Query: 206 DPSIPPPPRAPAPAPPGTVTQ 226
D IPPPP PAP PP +++
Sbjct: 136 DLLIPPPPPGPAPGPPQDISE 156
Score = 30.0 bits (66), Expect = 9.1
Identities = 22/75 (29%), Positives = 27/75 (36%), Gaps = 6/75 (8%)
Query: 578 GFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAP------SPPPTPA 631
G P DI PP + P +E P P+ PP P SPP T +
Sbjct: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLS 204
Query: 632 PVPVPLPPSTPAPVP 646
+P PP P P
Sbjct: 205 SPSIPTPPDFIPPAP 219
Score = 30.0 bits (66), Expect = 9.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Query: 210 PPPPRAPAPAPPGTVTQVDVRSRV 233
PPPP PAPAPP + V +R+
Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRL 249
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 597 RADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPV------SKV 650
+A P + + + + + R PPAP PP P+P P PP PA P+ +
Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 651 PANITRQNSSSSDS---GGSIVRDSQRHKQLPVD-RRKSQMEEVQDELIHRLTIGRSAAQ 706
PA T+ SSS + + PVD R SQME++++EL L R +
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
Query: 707 KKFHVPRQNV 716
H P V
Sbjct: 487 FLSHRPGPTV 496
Score = 37.4 bits (85), Expect = 0.057
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 590 PPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPP-----PTPAPVPVPLPPSTPAP 644
PP L PP HT+ + P P D P P+PP P P PVP P PP+ +P
Sbjct: 189 PPPPVLEALSPP--HTLSSPSI---PTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASP 242
Query: 645 VPVSK---VPANITRQNSSSSDSG 665
V P +T+ S + +G
Sbjct: 243 HTVGTRLFPPGGVTKWKSDVALNG 266
Score = 34.3 bits (77), Expect = 0.48
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 614 GPRPADTPPAPSPPPTPAPVPVPLPPS-TPAPVPV 647
G P +PP+ +PPP P + P PPS P P PV
Sbjct: 159 GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPV 193
Score = 30.0 bits (66), Expect = 9.1
Identities = 16/43 (37%), Positives = 18/43 (41%), Gaps = 8/43 (18%)
Query: 612 EYGPRPADTPPAPSPPP--------TPAPVPVPLPPSTPAPVP 646
+YG PP P P P P P+P PPST P P
Sbjct: 132 QYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPP 174
Score = 30.0 bits (66), Expect = 9.1
Identities = 11/21 (52%), Positives = 14/21 (66%)
Query: 206 DPSIPPPPRAPAPAPPGTVTQ 226
D IPPPP PAP PP +++
Sbjct: 136 DLLIPPPPPGPAPGPPQDISE 156
Score = 30.0 bits (66), Expect = 9.1
Identities = 22/75 (29%), Positives = 27/75 (36%), Gaps = 6/75 (8%)
Query: 578 GFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAP------SPPPTPA 631
G P DI PP + P +E P P+ PP P SPP T +
Sbjct: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLS 204
Query: 632 PVPVPLPPSTPAPVP 646
+P PP P P
Sbjct: 205 SPSIPTPPDFIPPAP 219
Score = 30.0 bits (66), Expect = 9.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Query: 210 PPPPRAPAPAPPGTVTQVDVRSRV 233
PPPP PAPAPP + V +R+
Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRL 249
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 597 RADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPV------SKV 650
+A P + + + + + R PPAP PP P+P P PP PA P+ +
Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 651 PANITRQNSSSSDS---GGSIVRDSQRHKQLPVD-RRKSQMEEVQDELIHRLTIGRSAAQ 706
PA T+ SSS + + PVD R SQME++++EL L R +
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
Query: 707 KKFHVPRQNV 716
H P V
Sbjct: 487 FLSHRPGPTV 496
Score = 37.4 bits (85), Expect = 0.057
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 590 PPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPP-----PTPAPVPVPLPPSTPAP 644
PP L PP HT+ + P P D P P+PP P P PVP P PP+ +P
Sbjct: 189 PPPPVLEALSPP--HTLSSPSI---PTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASP 242
Query: 645 VPVSK---VPANITRQNSSSSDSG 665
V P +T+ S + +G
Sbjct: 243 HTVGTRLFPPGGVTKWKSDVALNG 266
Score = 34.3 bits (77), Expect = 0.48
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 614 GPRPADTPPAPSPPPTPAPVPVPLPPS-TPAPVPV 647
G P +PP+ +PPP P + P PPS P P PV
Sbjct: 159 GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPV 193
Score = 30.0 bits (66), Expect = 9.1
Identities = 16/43 (37%), Positives = 18/43 (41%), Gaps = 8/43 (18%)
Query: 612 EYGPRPADTPPAPSPPP--------TPAPVPVPLPPSTPAPVP 646
+YG PP P P P P P+P PPST P P
Sbjct: 132 QYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPP 174
Score = 30.0 bits (66), Expect = 9.1
Identities = 11/21 (52%), Positives = 14/21 (66%)
Query: 206 DPSIPPPPRAPAPAPPGTVTQ 226
D IPPPP PAP PP +++
Sbjct: 136 DLLIPPPPPGPAPGPPQDISE 156
Score = 30.0 bits (66), Expect = 9.1
Identities = 22/75 (29%), Positives = 27/75 (36%), Gaps = 6/75 (8%)
Query: 578 GFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAP------SPPPTPA 631
G P DI PP + P +E P P+ PP P SPP T +
Sbjct: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLS 204
Query: 632 PVPVPLPPSTPAPVP 646
+P PP P P
Sbjct: 205 SPSIPTPPDFIPPAP 219
Score = 30.0 bits (66), Expect = 9.1
Identities = 12/24 (50%), Positives = 15/24 (62%)
Query: 210 PPPPRAPAPAPPGTVTQVDVRSRV 233
PPPP PAPAPP + V +R+
Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRL 249
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/128 (26%), Positives = 50/128 (39%), Gaps = 15/128 (11%)
Query: 580 VPNNILDIVRPPESGLG----------RADPPYTHTIQKQRMEYGPRPADTPPAPSPPPT 629
VP + + PP SG A PP + + + P P PP P PPP
Sbjct: 791 VPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPP-PPPV 849
Query: 630 PAPVPVPLPPSTPAPVPVSKVP----ANITRQNSSSSDSGGSIVRDSQRHKQLPVDRRKS 685
P PV +P P P P P ++T N +SSD + + ++ + +
Sbjct: 850 PGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEED 909
Query: 686 QMEEVQDE 693
EE +DE
Sbjct: 910 FEEEEEDE 917
>gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]
Length = 330
Score = 45.8 bits (107), Expect = 2e-04
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPP--ES 593
A +K+DF A ELS D+L+IL ++++W+K S G+VP N +DI P
Sbjct: 3 AVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGS-QEGYVPKNFIDIQFPKWFHE 61
Query: 594 GLGR 597
GL R
Sbjct: 62 GLSR 65
Score = 32.3 bits (72), Expect = 1.8
Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 523 RNYEPLKTQPK---KYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGF 579
R+ +P++ Q ++A++ YDF A + EL +++E+LD W G
Sbjct: 260 RHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGL 319
Query: 580 VPNN 583
P N
Sbjct: 320 FPAN 323
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 45.8 bits (107), Expect = 2e-04
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 3/50 (6%)
Query: 604 HTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKVPAN 653
HT+ + + + P P PP P PPP P P P PP P P+P ++VP++
Sbjct: 2007 HTMPNKALVHPPPP---PPPPPPPPLALPPPPPPPPPLPPPLPNAEVPSD 2053
Score = 30.4 bits (67), Expect = 7.0
Identities = 15/49 (30%), Positives = 21/49 (42%)
Query: 173 ANLISEDIESAISDSKGGKQKRRPDALRMISNADPSIPPPPRAPAPAPP 221
AN++S ++ D GG P+ + P PPPP P PP
Sbjct: 1987 ANMLSPNMPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPP 2035
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 9/115 (7%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDR--KQWWKVRNASGDSGFVPNNILDIVRPPES 593
A++ YDF + N E+S+ + ++L + ++ + W + N+ GD G P + + ++R PE
Sbjct: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEP 64
Query: 594 GL----GRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAP 644
G G P + E P P PPA PP A + P P P
Sbjct: 65 GPAGDGGPGAPARYANVPPGGFE--PLPV-APPASFKPPPDAFQALLQPQQAPPP 116
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 9/115 (7%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDR--KQWWKVRNASGDSGFVPNNILDIVRPPES 593
A++ YDF + N E+S+ + ++L + ++ + W + N+ GD G P + + ++R PE
Sbjct: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEP 64
Query: 594 GL----GRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAP 644
G G P + E P P PPA PP A + P P P
Sbjct: 65 GPAGDGGPGAPARYANVPPGGFE--PLPV-APPASFKPPPDAFQALLQPQQAPPP 116
>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
Length = 628
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 9/115 (7%)
Query: 536 AKSKYDFVARNNSELSVLKDDILEILDDR--KQWWKVRNASGDSGFVPNNILDIVRPPES 593
A++ YDF + N E+S+ + ++L + ++ + W + N+ GD G P + + ++R PE
Sbjct: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEP 64
Query: 594 GL----GRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAP 644
G G P + E P P PPA PP A + P P P
Sbjct: 65 GPAGDGGPGAPARYANVPPGGFE--PLPV-APPASFKPPPDAFQALLQPQQAPPP 116
>gi|41327712 v-crk sarcoma virus CT10 oncogene homolog isoform a
[Homo sapiens]
Length = 304
Score = 44.7 bits (104), Expect = 4e-04
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 16/118 (13%)
Query: 528 LKTQPKKYAKSKYDFVARNNSELSVLKDDILEILD-DRKQWWKVRNASGDSGFVPNNILD 586
L+ + +Y ++ +DF + +L K DIL I D +QWW ++ G G +P ++
Sbjct: 129 LRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVE 188
Query: 587 IVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAP 644
RP + + G + P P P P P P +TP P
Sbjct: 189 KYRPASASVSAL--------------IGGNQEGSHPQPLGGPEPGPYAQP-SVNTPLP 231
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,129,057
Number of Sequences: 37866
Number of extensions: 2008461
Number of successful extensions: 37241
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 577
Number of HSP's successfully gapped in prelim test: 512
Number of HSP's that attempted gapping in prelim test: 18031
Number of HSP's gapped (non-prelim): 12527
length of query: 822
length of database: 18,247,518
effective HSP length: 111
effective length of query: 711
effective length of database: 14,044,392
effective search space: 9985562712
effective search space used: 9985562712
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.