Search of human proteins with 56549656

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56549656 ARKadia-like 1 isoform b [Homo sapiens]
         (343 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56549656 ARKadia-like 1 isoform b [Homo sapiens]                   667   0.0  
gi|21450814 ARKadia-like 1 isoform a [Homo sapiens]                   596   e-171
gi|37595553 ring finger protein 111 [Homo sapiens]                    119   3e-27
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    54   2e-07
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]           45   7e-05
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    44   2e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         44   2e-04
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    43   4e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    43   4e-04
gi|50962882 G patch domain containing 8 [Homo sapiens]                 43   4e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        43   4e-04
gi|217330641 IWS1 homolog [Homo sapiens]                               43   5e-04
gi|63176611 modulator of estrogen induced transcription isoform ...    42   6e-04
gi|168229156 NFKB activating protein [Homo sapiens]                    41   0.001
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       41   0.002
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    41   0.002
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          40   0.002
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          40   0.002
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          40   0.002
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  40   0.003
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              40   0.004
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    39   0.007
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    39   0.007
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           39   0.007
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           39   0.007
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            39   0.009
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            39   0.009
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            39   0.009
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            39   0.009
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    39   0.009

>gi|56549656 ARKadia-like 1 isoform b [Homo sapiens]
          Length = 343

 Score =  667 bits (1722), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM
Sbjct: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60

Query: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120
           ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA
Sbjct: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120

Query: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180
           ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK
Sbjct: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180

Query: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH 240
           ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH
Sbjct: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH 240

Query: 241 LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS 300
           LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS
Sbjct: 241 LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS 300

Query: 301 GTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 343
           GTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL
Sbjct: 301 GTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 343


>gi|21450814 ARKadia-like 1 isoform a [Homo sapiens]
          Length = 404

 Score =  596 bits (1537), Expect = e-171
 Identities = 329/404 (81%), Positives = 330/404 (81%), Gaps = 61/404 (15%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM
Sbjct: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60

Query: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120
           ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA
Sbjct: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120

Query: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180
           ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK
Sbjct: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180

Query: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIP-- 238
           ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIP  
Sbjct: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDG 240

Query: 239 ----GHLDPGFLASD-------------------------------KTSAGNAPLNEE-- 261
                H D     SD                               +TS     LN E  
Sbjct: 241 PPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAG 300

Query: 262 ----------------------INIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHG 299
                                 INIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHG
Sbjct: 301 HLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHG 360

Query: 300 SGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 343
           SGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL
Sbjct: 361 SGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 404


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score =  119 bits (299), Expect = 3e-27
 Identities = 94/265 (35%), Positives = 141/265 (53%), Gaps = 17/265 (6%)

Query: 86  ESDSS-NHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSR 144
           ++DSS + C+ SPSSS H  DSDT++S E+ E S   +    +    S +    K  R+ 
Sbjct: 129 DNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTE 188

Query: 145 SESETSTMAAKKNRQSSDKQNGRVAK--VKGH---RSQKHKERIRLLRQKREAAARKKYN 199
           +ES +  +  +     S  +     K  VK +   R+QK KERI + R+KRE  AR+KY 
Sbjct: 189 TESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYA 248

Query: 200 LL-QDSSTSDSDLTCDSSTSSSDDDEE-----VSGSSKTITAEIPGHLDPGFLASDKTSA 253
           LL   SS+S++DL+ +SS+SSS + EE      S + +   A   G +D   +  + +S 
Sbjct: 249 LLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASST 308

Query: 254 GNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSW 313
                NEEIN+ S+DSEVEIV V E  R    R  +  S S W  GS +     ++ ++ 
Sbjct: 309 PQVTANEEINVTSTDSEVEIVTVGESYR---SRSTLGHSRSHWSQGSSSHASRPQEPRNR 365

Query: 314 TAVTP--QQTWASPAEVVDLTLDED 336
           + ++   Q    + AEVVDLT+DED
Sbjct: 366 SRISTVIQPLRQNAAEVVDLTVDED 390



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 27/104 (25%), Positives = 54/104 (51%), Gaps = 5/104 (4%)

Query: 53  SSMPCLLMELRRDSSESQLASTESDKPT----TGRVYESDSSNHCMLSPSSSGHLADSDT 108
           S +  ++  LR++++E    + + D+PT    T    ES +++  + + + S     SDT
Sbjct: 366 SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDT 425

Query: 109 LSSAEENEPSQ-AETAVEGDPSGVSGATVGRKSRRSRSESETST 151
            S+   ++PS  +ET+     +  +G ++G  SRR+ S + T T
Sbjct: 426 ASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 58/257 (22%), Positives = 104/257 (40%), Gaps = 18/257 (7%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           +S++   ++  +++   D S   +S    D  +DS+   S          DSS+S   S 
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES----------DSSDSDSKSD 641

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            SD  ++     SDSS+    S +SS     SD+  S++ +  S +  + +   S  S  
Sbjct: 642 SSDSNSSDSSDNSDSSD----SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697

Query: 135 TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVA-KVKGHRSQKHKERIRLLRQKREAA 193
           +         S+S++S  +   N  SSD  +   +       S    +          + 
Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757

Query: 194 ARKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHLDPGFLASDKTS 252
           +    N    S +SDS  + DSS SS S+D    S SS +  +    +      +SD + 
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817

Query: 253 AGNAPLNEEINIASSDS 269
           + ++  ++  N  SSDS
Sbjct: 818 SDSSNSSDSSN--SSDS 832



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 59/257 (22%), Positives = 106/257 (41%), Gaps = 8/257 (3%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +   +++   DGS + +S  + D    S    S          DSS+S  +S  
Sbjct: 833  SDSSNSSDSSDSSDSSDGS-DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 76   SDKPTTGRVYESDSSNHCMLSPSS-SGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            SD   +    +SDSS+    S SS S + +DS   S++ +N  S ++++   D S  S +
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS-SDSSNSSDSSDSSDS 950

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
            +    S  S   S +S  +   +  SSD  N   +      S               + +
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS----DSSNSSDS 1006

Query: 195  RKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSA 253
                +    S++SDS  + DSS SS S D  + S SS +  +           +SD + +
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066

Query: 254  GNAPLNEEINIASSDSE 270
             ++  + + + +S  SE
Sbjct: 1067 SDSSDSSDSSDSSDSSE 1083



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 55/249 (22%), Positives = 102/249 (40%), Gaps = 12/249 (4%)

Query: 22  ASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTT 81
           ++  +++   D S    S    D    S    S          DSS+S  +S  S+   +
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704

Query: 82  GRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSR 141
               +SDSS+    S SS+ + +DSD+ +S++ ++ S +  +   D S  S ++    S 
Sbjct: 705 SDSSDSDSSDS---SDSSNSNSSDSDSSNSSDSSDSSNSSDS--SDSSDSSNSSDSSDSS 759

Query: 142 RSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLL 201
            S + S++S   +  +  SSD  N   +    + S              +++     +  
Sbjct: 760 DSSNSSDSSD--SSDSSDSSDSSNSSDSNDSSNSSDSSDSS-----NSSDSSNSSDSSDS 812

Query: 202 QDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEE 261
            DSS SDS  + DSS SS   D   S  S   +    G        SD +++ ++  + +
Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872

Query: 262 INIASSDSE 270
            + +S  S+
Sbjct: 873 SSNSSDSSD 881



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 46/209 (22%), Positives = 90/209 (43%), Gaps = 3/209 (1%)

Query: 65  DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADS--DTLSSAEENEPSQAET 122
           DSS+S  +S  SD  +     ESDSS+    S SS  + +DS  ++ SS   N  + +++
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668

Query: 123 AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
           +   D S  S ++    S  S   S++S  +   +   S   +   +    + +    + 
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDS 728

Query: 183 IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHL 241
                    + +    +    S++SDS  + DSS SS S D  + S SS +  +      
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS 788

Query: 242 DPGFLASDKTSAGNAPLNEEINIASSDSE 270
                +SD +++ ++  + + + +S  S+
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 49/211 (23%), Positives = 87/211 (41%), Gaps = 14/211 (6%)

Query: 65   DSSESQLASTESDKPTTGRVYESDSSNHCMLSPS-----SSGHLADSDTLSSAEENEPSQ 119
            DSS+S  +S  SD   +    +SDSSN    S S     SS     SD+  S++ NE S 
Sbjct: 831  DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890

Query: 120  AETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH 179
            +  +   D S  S +     S  S S   +++  + ++  SSD  N   +      S   
Sbjct: 891  SSDS--SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948

Query: 180  KERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPG 239
                        + +    +    S +SDS+ +  S +S+S D  + S SS +  +    
Sbjct: 949  D-------SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001

Query: 240  HLDPGFLASDKTSAGNAPLNEEINIASSDSE 270
            +      +SD + + N+  +   + +S+ S+
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 55/258 (21%), Positives = 101/258 (39%), Gaps = 19/258 (7%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           +S     +S+   + + D S    S       +DS+  S           DSS+S  +S 
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLS-SAEENEPSQAETAVEGDPSGVSG 133
            SD         SDSS+    S  S    +DSD+ S S++ N    ++ +   D S  S 
Sbjct: 613 SSD--------SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664

Query: 134 ATVGRKSRRSRSESETSTMA-AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
           ++    S  S   S +S  + +  +  SSD  N   +      S              ++
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS---------DSSDS 715

Query: 193 AARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTS 252
           +     N     S++ SD +  S++S S D  + S SS +  +    +      +SD + 
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775

Query: 253 AGNAPLNEEINIASSDSE 270
           + ++  + + N +S+ S+
Sbjct: 776 SSDSSNSSDSNDSSNSSD 793



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 58/270 (21%), Positives = 104/270 (38%), Gaps = 25/270 (9%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   ++  +++   D S   +S    D    S    S          DSS S  +S  
Sbjct: 756  SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS---------DSSNSSDSSNS 806

Query: 76   SDKPTTGRVYESDSSNHCMLSPSS----SGHLAD----------SDTLSSAEENEPSQAE 121
            SD   +    +SDSSN    S SS    S + +D          SD+ SS   +  + ++
Sbjct: 807  SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 122  TAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKE 181
            ++   D S  S ++    S  S + S++S  +   +  SSD  N   +    + S   + 
Sbjct: 867  SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926

Query: 182  RIRLLRQKREAAARK--KYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPG 239
                       ++      +    S++SDS  + DSS SS   D   S SS +  +    
Sbjct: 927  SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986

Query: 240  HLDPGFLASDKTSAGNAPLNEEINIASSDS 269
                   +SD + + N+  + + + +S  S
Sbjct: 987  DSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 55/258 (21%), Positives = 100/258 (38%), Gaps = 10/258 (3%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           +S +   +   +++   + S   +S    D    S+   S          DSS S  +S 
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            SD   +     SDSSN       SS     SD+ +S++ ++ S +  + +   S  S  
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 135 TVGRKSRRSRSESETSTMAAKKN--RQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
           +         S+S  S+ ++  N    SSD  +   +    + S              ++
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS-----SDSSDS 818

Query: 193 AARKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHLDPGFLASDKT 251
            +    +    S +SDS  + DSS SS S D  +   S+++ ++      D    ++   
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878

Query: 252 SAGNAPLNEEINIASSDS 269
           S+ ++  NE  N  SSDS
Sbjct: 879 SSDSSDSNESSN--SSDS 894



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 58/261 (22%), Positives = 98/261 (37%), Gaps = 29/261 (11%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
            +S++   +    ++   D S   +S    D    S   SS        R DSS S  +S 
Sbjct: 817  DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN-------RSDSSNSSDSSD 869

Query: 75   ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
             SD   +    +S  SN    S  SS     SD+ SS   N    ++++   D S  S +
Sbjct: 870  SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQ----SSDKQNGRVAKVKGHRSQKHKERIRLLRQKR 190
            +    S  S + S++S  +   N      SSD  N   +                     
Sbjct: 930  SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS-----------------DSN 972

Query: 191  EAAARKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHLDPGFLASD 249
             + +    N    S +SDS  + DSS SS S D  + S SS +  +    +      +SD
Sbjct: 973  SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032

Query: 250  KTSAGNAPLNEEINIASSDSE 270
             + + ++  + + + +S  S+
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSD 1053



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 52/257 (20%), Positives = 98/257 (38%), Gaps = 5/257 (1%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
            +S      S+ +++   D S   +S    D    S    S          DSS+S  +S 
Sbjct: 843  DSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902

Query: 75   ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
                 ++     SDSSN    S SS+     + + SS   +    ++++   D S  S +
Sbjct: 903  SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
            +    S  S S   + +  +  +  SSD  +   +    + S               + +
Sbjct: 963  SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS----DSSDSSNS 1018

Query: 195  RKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSA 253
                N    S++SDS  + DSS SS S D  + S SS +  +           +SD + +
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078

Query: 254  GNAPLNEEINIASSDSE 270
             ++  + + + +S+ S+
Sbjct: 1079 SDSSESSDSSDSSNSSD 1095



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 44/218 (20%), Positives = 85/218 (38%), Gaps = 1/218 (0%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +   +++   D S   +S    D    S    S          DSS+S  +S  
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA-ETAVEGDPSGVSGA 134
            SD   +    +S  S+    S +SS     S++  S++ ++ S + +++   D S  S +
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
            +    S  S   S++S  +   +   S   +          S    +          + +
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237

Query: 195  RKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKT 232
                +    S++SDS  + DSS S+SD ++E    SK+
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 49/257 (19%), Positives = 99/257 (38%), Gaps = 12/257 (4%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +    ++   D S   +S    D    S    S          DSS+S  +S  
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGAT 135
            SD   +    +S  S++   S  SS     SD+ +S++ ++ S++  + +   S  S  +
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165

Query: 136  VGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAAR 195
                     S+S  S+ ++  +  SSD  +   +      S              +++  
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSS-DSSDSSDSSDSSDSSDSSDSS-----------DSSDS 1213

Query: 196  KKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGN 255
               +   DSS S      + S+ SSD  +    S+ + +++     D    ++D++ + +
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273

Query: 256  APLNEEINIASSDSEVE 272
               N   N + SDS+ E
Sbjct: 1274 KSGNGNNNGSDSDSDSE 1290



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 53/258 (20%), Positives = 100/258 (38%), Gaps = 9/258 (3%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +    ++   D S   +S    D    S   +S          DSS+S  +S  
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGAT 135
            SD   +    +S +S+    S  SS     SD+  S++ ++ S +  + +   S  S  +
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138

Query: 136  VGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAAR 195
                     SES  S+ ++  +  SSD  +   +      S               + + 
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSS-DSSDSSDSSDSSDSSDSSNSSD-------SSDSSDSS 1190

Query: 196  KKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAG 254
               +    S +SDS  + DSS SS S D  + S SS +  +           +SD +++ 
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250

Query: 255  NAPLNEEINIASSDSEVE 272
            ++  + + + ++SDS  E
Sbjct: 1251 DSSDSSDSSDSTSDSNDE 1268



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 48/241 (19%), Positives = 88/241 (36%), Gaps = 1/241 (0%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +   +++   D S   +S    D    S    S          DSS+S  +S  
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA-ETAVEGDPSGVSGA 134
            SD   +     S  S+    S  SS     SD+  S+E ++ S + +++   D S  S +
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
            +    S  S   S++S  +   +   S   +          S    +          + +
Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231

Query: 195  RKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAG 254
             +  +    S +SDS  + DSS SS   D     + ++ +    G+ +     SD  S G
Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291

Query: 255  N 255
            +
Sbjct: 1292 S 1292



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 57/257 (22%), Positives = 97/257 (37%), Gaps = 24/257 (9%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
            +S     +S+  ++   D S   +S    D    S    S          +SS+S  +S 
Sbjct: 961  DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS---------NSSDSSDSSD 1011

Query: 75   ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
             SD   +     S  S++   S  SS     SD+  S++ ++ S +  +   D S  S +
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS--SDSSDSSDS 1069

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
            +    S  S   SE+S  +   N  SSD  +   +      S               + +
Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSN--SSDSSDSSDSSDSSDSSD----------SSDSSDS 1117

Query: 195  RKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSA 253
                N    S +SDS  + DSS SS S D  E S SS +  +           +SD + +
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 254  GNAPLNEEINIASSDSE 270
             N+  + + + +S  S+
Sbjct: 1178 SNSSDSSDSSDSSDSSD 1194



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 44/209 (21%), Positives = 86/209 (41%), Gaps = 34/209 (16%)

Query: 63  RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAET 122
           + DS + +  S++SD         SDSSN    S SS    +DS++ S ++ ++   +++
Sbjct: 539 KSDSGKGKSDSSDSDS--------SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590

Query: 123 AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
           + + D S  S ++    S  S   S++S  +  K+  S  + +   +  K   S  +   
Sbjct: 591 S-DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS-- 647

Query: 183 IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSS--SDDDEEVSGSSKTITAEIPGH 240
                                S +SD+  + DSS SS  SD  +    S  + +++    
Sbjct: 648 ---------------------SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686

Query: 241 LDPGFLASDKTSAGNAPLNEEINIASSDS 269
            D    +    S+ ++  ++  +  SSDS
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDS 715



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 43/204 (21%), Positives = 78/204 (38%), Gaps = 10/204 (4%)

Query: 72  ASTESDKPTTGR-VYESDSSNHCMLSPSSSGHL-ADSDTLSSAEENEPSQAETAVEGDPS 129
           ++T SD  + G   Y+ D  +     P+SS     + D  S ++ N  S+ + +   D S
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDES 498

Query: 130 ---GVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLL 186
              G    + G +   S S S+T+   +  N  + +  N +    KG       +     
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSS 558

Query: 187 RQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFL 246
                + +        DSS S+S    DSS S S D  +   S  + +++     D    
Sbjct: 559 NSSDSSDSSDS-----DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613

Query: 247 ASDKTSAGNAPLNEEINIASSDSE 270
           +    S+ +   + +    SSDS+
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSD 637



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 28/117 (23%), Positives = 45/117 (38%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +   +++   D S   +S    D    S    S          DS+ES  +S  
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVS 132
            SD   +    +S  S+    S S S   +DS + S    N  S +++  EG  S  S
Sbjct: 1241 SDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 46/232 (19%), Positives = 90/232 (38%), Gaps = 24/232 (10%)

Query: 13  LIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLA 72
           +++ + P  A    +   ED  +E   + + +    +  I+S        R  + E+++ 
Sbjct: 178 VVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSK-------RNGTKEAEVT 230

Query: 73  STESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVS 132
                 P TG     D+S+    SPS +G   D D  S  +E+E +        +  G  
Sbjct: 231 ------PGTGEDAGLDNSDG---SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQE 281

Query: 133 GATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
           G   G++     S  + S      + +  +  +  V   K  +S+++   I      +  
Sbjct: 282 GQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRI 341

Query: 193 AARKKYNLLQDSSTSDSDLTCDSST----SSSDDDEEVSGSS---KTITAEI 237
              +K N  ++S   ++ +T +S T     S D   E+ G S   + IT E+
Sbjct: 342 EDTQKLN-HRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEV 392


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 69/312 (22%), Positives = 119/312 (38%), Gaps = 25/312 (8%)

Query: 2    KMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKD-GVADSTVISSMPCLLM 60
            K  E +G+ +++I ++      +  T K+E  S+  ES   ++     ++  +  P L  
Sbjct: 1460 KESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHNSKHNKSPTLSC 1519

Query: 61   E--LRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLA----DSDTLSSAEE 114
               + ++S  S LA   S    TG    SDS    +LS SS   LA       T    + 
Sbjct: 1520 RFAILKESPRSLLAQKSSHLEETG----SDSGT--LLSTSSQASLARFSMKKSTSPETKH 1573

Query: 115  NEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGH 174
            +E     + +  D S  S AT       SR   E  ++A  K  ++ D+++  +++ +  
Sbjct: 1574 SEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELISEGRPV 1633

Query: 175  RSQKHKE---------RIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEE 225
             +    E           RL R K +   +      ++S  S+   T  S TSS D   +
Sbjct: 1634 ETDSESEFPVFPTALTSERLFRGKLQEVTKSSR---RNSEGSELSCTEGSLTSSLDSRRQ 1690

Query: 226  VSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHP 285
            +  S K I  +           SD  S G+A   +E    +   +V   G    +     
Sbjct: 1691 LFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLTPT 1750

Query: 286  RGGVIQSVSSWK 297
            RG   +   +WK
Sbjct: 1751 RGESEKQEPTWK 1762


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 63/309 (20%), Positives = 118/309 (38%), Gaps = 47/309 (15%)

Query: 2    KMEEAVGKVEELIESE-APPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
            K  E+   ++   +SE +  +A++    KE+ G +E     Q+    +    S   C   
Sbjct: 797  KYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHS 856

Query: 61   ELR----RDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENE 116
            + R      S   +  S    K   G  ++S+S++   ++ +S      S      E   
Sbjct: 857  KKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATS 916

Query: 117  PSQAETA---VEGDPSGVS----------GATVGRKSRRSRSESETSTMAAKKNRQSSDK 163
             S++E +   ++  P+  S          GA    K R S S+SE S   ++ NR    K
Sbjct: 917  DSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQK 976

Query: 164  -QNGRVAKVKGHRSQKHKERIRLLRQKREAAARKK----------YNLLQDSSTSDSDLT 212
             ++G    +K   ++K KE+++  + K+  A ++K          +   ++    D  +T
Sbjct: 977  HKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVT 1036

Query: 213  CDSS----------------TSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNA 256
             +S                  +    +E++SG   T+T  +   LD       K S    
Sbjct: 1037 QESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVT--VSSDLDQFTKDDSKLSISPT 1094

Query: 257  PLNEEINIA 265
             LN E N+A
Sbjct: 1095 ALNTEENVA 1103



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 61/249 (24%), Positives = 99/249 (39%), Gaps = 48/249 (19%)

Query: 63  RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAET 122
           R  SS S   +  SD     R     SS++  +S S  G  A     SS ++N  S  + 
Sbjct: 720 RSPSSRSHSRNKYSDHSQCSR-----SSSYTSIS-SDDGRRAKRRLRSSGKKNSVSHKKH 773

Query: 123 AVEGDPS-------GVSGATVGRKSRRSRS------ESETSTMAAKKNRQSSDKQ----- 164
           +   + +       G   ++  RK   SRS      +SE S++ A ++ Q  +KQ     
Sbjct: 774 SSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMER 833

Query: 165 -------NGRVAKVKGHRSQKHKERIRLLRQK-----REAAARKKYNLL----QDSSTSD 208
                  N    K K  R   H ++ R L++      R  +  K+ N         S S+
Sbjct: 834 THNKQEKNRGEEKSKSERECPHSKK-RTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSE 892

Query: 209 SDLT----CDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSA---GNAPLNEE 261
            D+T     DS  SS  ++ E +  S++  +EI   + P   +S  TS      A  + +
Sbjct: 893 RDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSK 952

Query: 262 INIASSDSE 270
              ++SDSE
Sbjct: 953 QRTSTSDSE 961


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 10/143 (6%)

Query: 96   SPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAK 155
            S SSS   + S + SS+  +  S+ E   EGD +G  G   G ++  + S    S  ++ 
Sbjct: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616

Query: 156  KNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDS 215
             +  SS   +   +      S               +++    +    SS+S S  +  S
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSS----------SSSSSSSSSSSSSSSSSSSSSSSS 2666

Query: 216  STSSSDDDEEVSGSSKTITAEIP 238
            S+SSS  DE+ S SS    A  P
Sbjct: 2667 SSSSSTTDEDSSCSSDDEAAPAP 2689



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 66   SSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
            SS S  +S+ S   ++     S SS+    S SSS   + S + SS+  +  +  +++  
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCS 2680

Query: 126  GDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS 161
             D       T G  ++ +      +T  A K R S+
Sbjct: 2681 SDDEAAPAPTAGPSAQAALPTK--ATKQAGKARPSA 2714


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/160 (21%), Positives = 68/160 (42%), Gaps = 15/160 (9%)

Query: 110 SSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVA 169
           S +EE E S   ++   D    SG+  G +   S  E +++  +++ +    D ++GR +
Sbjct: 677 SESEEEEDSSDSSS---DSESESGSESGEQGE-SGEEGDSNEDSSEDSSSEQDSESGRES 732

Query: 170 KVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSG 228
            ++  R+ K   + +      +     + +   DSS  +S    DSS+ S S+ + E   
Sbjct: 733 GLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESES 792

Query: 229 SSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSD 268
            S+ +T E             KT     PL +++++   D
Sbjct: 793 ESRRVTKE----------KEKKTKQDRTPLTKDVSLLDLD 822



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 30/146 (20%), Positives = 53/146 (36%), Gaps = 10/146 (6%)

Query: 65  DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAV 124
           DSS    + + S+    G   E   SN      SSS   ++S   S  E    ++  +  
Sbjct: 687 DSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKA 746

Query: 125 EGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIR 184
           +G      G     KS+ S S ++ S+     +  S  +             +   E  R
Sbjct: 747 KGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESES----------EPESESESRR 796

Query: 185 LLRQKREAAARKKYNLLQDSSTSDSD 210
           + ++K +   + +  L +D S  D D
Sbjct: 797 VTKEKEKKTKQDRTPLTKDVSLLDLD 822


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 56/263 (21%), Positives = 97/263 (36%), Gaps = 45/263 (17%)

Query: 11  EELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQ 70
           ++ +E + P ++SE +++ E D S E E +     V         P             +
Sbjct: 310 KKAVEKQQPVESSE-DSSDESDSSSEEEKKPPTKAVVSKATTKPPPA-----------KK 357

Query: 71  LASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSG 130
            A + SD        +SDSS         +G   +S    +     P+    A    P G
Sbjct: 358 AAESSSDSS------DSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVG 411

Query: 131 VSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKR 190
                + RK+  S SE E+S+                        S++ K +  +   K 
Sbjct: 412 GGQKLLTRKADSSSSEEESSS------------------------SEEEKTKKMVATTKP 447

Query: 191 EAAARKKYNL-LQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASD 249
           +A A+   +L  + +     D + DS +SSS+++EE   +SK+   + P  +  G   S 
Sbjct: 448 KATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEE--KTSKSAVKKKPQKVAGGAAPSK 505

Query: 250 KTSAGNAPLNEEINIASSDSEVE 272
             SA         + +S DS  E
Sbjct: 506 PASAKKGKAESSNSSSSDDSSEE 528



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           + EAP K +          +V  +S   K   A    +     LL   + DSS S+  S+
Sbjct: 373 DDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTR-KADSSSSEEESS 431

Query: 75  ESDKPTTGRVYESDS---------SNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
            S++  T ++  +           S     +P  S   +     SS+EE E   +++AV+
Sbjct: 432 SSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK 491

Query: 126 GDPSGVSGATVGRK---SRRSRSESETSTMAAKKNRQSSDKQNGR 167
             P  V+G     K   +++ ++ES  S+ +   + +  +K  G+
Sbjct: 492 KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGK 536



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 46/237 (19%), Positives = 88/237 (37%), Gaps = 30/237 (12%)

Query: 63  RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENE----PS 118
           ++D++ S L    S    + +V E     +  ++  +    + SD+  S+EE E    P 
Sbjct: 42  QQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPP 101

Query: 119 QAETAVEGDPSGVSGATVGRKSRRSRSESETS-----------------------TMAAK 155
             + AV     G+       K+  S S  E+S                         A  
Sbjct: 102 AKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPP 161

Query: 156 KNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDS 215
           K  +SSD  +   ++ +  ++QK K     ++ + +A  +      + ++   +  +  S
Sbjct: 162 KKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSS 221

Query: 216 STSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVE 272
           S+SSS DD E   ++ T    +P       +A     A   P  +  +   S S+ E
Sbjct: 222 SSSSSSDDSEEEKAAATPKKTVP---KKQVVAKAPVKAATTPTRKSSSSEDSSSDEE 275



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 41/178 (23%), Positives = 67/178 (37%), Gaps = 23/178 (12%)

Query: 154 AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTC 213
           AKK   SSD ++          S + +E ++    K+ A   K+  L    + + +  + 
Sbjct: 78  AKKKASSSDSED----------SSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESS 127

Query: 214 DSSTSSSDDDEE----------VSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEIN 263
            S  SS DDDEE          V   +K   A  P         SD +S    P N++  
Sbjct: 128 SSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP-PKKAKSSDSDSDSSSEDEPPKNQKPK 186

Query: 264 IASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQT 321
           I     + +     + AR   P+    ++ SS    S +   S    +   A TP++T
Sbjct: 187 ITPVTVKAQTKAPPKPARAA-PKIANGKAASS-SSSSSSSSSSDDSEEEKAAATPKKT 242


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 30/187 (16%)

Query: 73  STESDKPTTGRVYE-SDSSNHCMLSPSSSGHLADSDTLSSAEEN---------------- 115
           S  S K  +G+ +       H   S     H AD++  SS  E+                
Sbjct: 661 SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK 720

Query: 116 --EPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKG 173
              P+ +E   + +P G       R+ RR++ +S+  ++ A++       + G  +  + 
Sbjct: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780

Query: 174 HRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTS-----------SSDD 222
           H  +KHK  +     +R A  ++       S  S  D   D ++S           S ++
Sbjct: 781 HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE 840

Query: 223 DEEVSGS 229
           +EE SGS
Sbjct: 841 EEEDSGS 847



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 19/148 (12%)

Query: 87  SDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGV----SGATVGRK--- 139
           S  S+H    PSS    +D  +     +  PSQ     E + SG     S +  GR+   
Sbjct: 804 SSRSSH-RSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSS 862

Query: 140 ---SRRSRSESETS----TMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
              SRRS S S  +    +  +++   S D  +    + + H  + H          +  
Sbjct: 863 HRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHR 922

Query: 193 AARKKYNLLQDSSTSDSDLTCDSSTSSS 220
           + R KY+    SS  D  L+C  S S S
Sbjct: 923 SKRHKYS----SSDDDYSLSCSQSRSRS 946


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 58/283 (20%), Positives = 110/283 (38%), Gaps = 31/283 (10%)

Query: 2   KMEEAVGKVEELIESEAPPKASEQETAKE-EDGSVELESQVQKDGVADSTVISSMPCL-L 59
           K EE + ++E  +     P   + E  +  E   +ELE  +++ G  +  +   +    L
Sbjct: 37  KGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRL 96

Query: 60  MELRRDSSESQLASTESDKPTTGRVYE----SDSSNHCMLSPSS-SGHLADSDTLS---- 110
           M L +D +      T   +P     ++    ++  N  + +    S    D  +      
Sbjct: 97  MLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRR 156

Query: 111 SAEENEPSQA---------ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS 161
           + E  +P+           E++    P+        +K R  RSES +     KK+ +  
Sbjct: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216

Query: 162 DKQNGRVAKVKGHRS----QKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSST 217
             ++   +K + HRS     K K + +  ++ R      K      S+++DS  + D+S 
Sbjct: 217 KHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR 276

Query: 218 SSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNE 260
           S S      S ++KT T  + G       AS +   G+AP +E
Sbjct: 277 SRSR-----SAAAKTHTTALAGRSPSP--ASGRRGEGDAPFSE 312



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 55/214 (25%), Positives = 88/214 (41%), Gaps = 23/214 (10%)

Query: 65   DSSESQLASTE----SDKPTTGRVYESDSS---NHCMLSPSSSG--HLADSDTLSSAEEN 115
            D S   +A T     S   ++G V  + SS   ++ MLS  + G  H    +  +S    
Sbjct: 2457 DQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ 2516

Query: 116  EPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHR 175
            +PS A  A++      S ++    S  S S S +S+ ++     SSD + G    V+   
Sbjct: 2517 QPS-ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE-GSSLPVQPEV 2574

Query: 176  SQKH--------KERIRLLRQKREAAARKKY----NLLQDSSTSDSDLTCDSSTSSSDDD 223
            + K         KE +R  R      A++K     +    SS+S S  +  SS+SSS   
Sbjct: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634

Query: 224  EEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAP 257
               S SS + ++  P    PG  A  K ++   P
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP 2668



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 27/103 (26%), Positives = 42/103 (40%)

Query: 63   RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAET 122
            RR SS S  +S+ S   ++     S S +    S  SS  +     L       P+  E 
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589

Query: 123  AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQN 165
              EG P   + A   R+S  S S S +S+ ++  +  SS   +
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632



 Score = 35.0 bits (79), Expect = 0.098
 Identities = 38/141 (26%), Positives = 53/141 (37%), Gaps = 31/141 (21%)

Query: 63   RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAET 122
            RR SS S  +S+ S          S SS+    S SSS   + S + SS+  + PS A+ 
Sbjct: 2605 RRSSSSSSSSSSSS----------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654

Query: 123  AVEGDPSGVSGATVGRKSRRSRS--------------------ESETSTMAAKKNRQSSD 162
              +  P   S        RRSRS                        S   + +++QSS 
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSS 2714

Query: 163  KQNGRVAKVKG-HRSQKHKER 182
             + G     +G  RS  HK R
Sbjct: 2715 SERGSRRGQRGDSRSPSHKRR 2735



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 9/114 (7%)

Query: 57   CLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENE 116
            CL  +  R  SES +      +   G+   S SS    + PS+S         S ++ + 
Sbjct: 1509 CLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS-----PQERSESDSSP 1563

Query: 117  PSQAETAVEGDPSGVSGAT--VGRKSRRS--RSESETSTMAAKKNRQSSDKQNG 166
             S+A+T         SG++  V  KSR S  RS S +S     K R +   Q+G
Sbjct: 1564 DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSG 1617



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 48/212 (22%), Positives = 77/212 (36%), Gaps = 37/212 (17%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQV-----QKDGVADSTVISSMPCLLMELRRDSSES 69
            E +  P AS QE + E D S + +++      Q+     S  + S   L     R  S  
Sbjct: 1544 ELDVKPSASPQERS-ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602

Query: 70   QLASTESDKPTTGRVYESDSSN--------------HCMLSPSSSGHLADSDTLSSAEEN 115
            ++     DKP      +S S +                    SS G     +  SS E +
Sbjct: 1603 EV----KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658

Query: 116  --EPSQAETAVEG-----DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRV 168
               P ++ TA  G     +P   S     R+S RS  E       ++++R +S     R 
Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718

Query: 169  AKVKGHR------SQKHKERIRLLRQKREAAA 194
                 HR      S +  E+ R  R++R A++
Sbjct: 1719 RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS 1750


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 66/292 (22%), Positives = 112/292 (38%), Gaps = 49/292 (16%)

Query: 15  ESEAPPKASEQETAKEEDGSVELES----QVQKDGVADSTVISSMPCLLMELRRDSSE-- 68
           ESE PP+    ++  EE     +      ++ K  V+DS   S  P        ++ E  
Sbjct: 186 ESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSE--SEEPPRHQASDSENEELP 243

Query: 69  -SQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENE------PSQAE 121
             +++ +ES+ P   R   SDS N  +  P  S   ++    + A ++E      P  ++
Sbjct: 244 KPRISDSESEDPP--RHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSD 301

Query: 122 TAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNR----------------------Q 159
           +  EG   G +  +    + R + + E+   + ++N+                       
Sbjct: 302 SESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFH 361

Query: 160 SSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSS 219
           SSD +     K K    +  KE       KR+AA        + +S   S +  D+  S 
Sbjct: 362 SSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSD 421

Query: 220 SDDDEEVSGS-SKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSE 270
           SD   + SG   KTI ++     + G   SDK        NEE ++  SDSE
Sbjct: 422 SDAVSDKSGKREKTIASD--SEEEAGKELSDKK-------NEEKDLFGSDSE 464


>gi|63176611 modulator of estrogen induced transcription isoform a
           [Homo sapiens]
          Length = 1034

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 61/251 (24%), Positives = 104/251 (41%), Gaps = 36/251 (14%)

Query: 9   KVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSE 68
           +  ELIE+E       ++  KE+  S E+E+Q  +D     T +++      E  +D + 
Sbjct: 150 RAHELIEAEGI-----EDIEKEDIESQEIEAQEGED----DTFLTAQDGEEEENEKDIAG 200

Query: 69  SQLASTESDKP--TTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEG 126
           S   + E  KP  + G + E+D + H  +   ++   A+ D +S        QAE A+  
Sbjct: 201 SGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVT-----IQAEDAITL 255

Query: 127 DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERI--- 183
           D  G      G+  + + SE+           QS +K++        H+  K ++ +   
Sbjct: 256 DFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGD 315

Query: 184 ------RLLRQKREAAARKKYNLLQDSST--------SDSDLTCDSSTSSSDD---DEEV 226
                 R   +K E+  ++K  L +  S+        S S  + DS TSS DD       
Sbjct: 316 PVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSST 375

Query: 227 SGSSKTITAEI 237
           SGSS + T  I
Sbjct: 376 SGSSGSSTKNI 386



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 114 ENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAK 170
           + +PS+ E   E D    S ++  +K+   RS S+T     K+ ++SS+K   + +K
Sbjct: 461 KGDPSKKEMKKENDEKSSSRSSGDKKNTSDRS-SKTQASVKKEEKRSSEKSEKKESK 516


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 51/213 (23%), Positives = 84/213 (39%), Gaps = 33/213 (15%)

Query: 59  LMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPS 118
           L++  R+ S  Q   +E +     R+ E  +     LSP +     DSD  +  E+ EP 
Sbjct: 117 LLDKEREESLRQKRLSERE-----RIGELGAPEVWGLSPKNPE--PDSDEHTPVEDEEPK 169

Query: 119 QAETAV---EGDPSGVSGATVGRKSRRSRSES---------ETSTMAAKKNRQSSDKQNG 166
           ++ T+    E +    S  +  R  +R + +S         E S   +     SSD+ N 
Sbjct: 170 KSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNK 229

Query: 167 RVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEV 226
           R AK    + +K K R +  ++KR   +RK+              + DSS+  S ++   
Sbjct: 230 RRAKKAKKKEKKKKHRSKKYKKKRSKKSRKE--------------SSDSSSKESQEEFLE 275

Query: 227 SGSSKTITAEIPGHLDPGFLASDKTSAGNAPLN 259
           +       AE P  L         TS  + PLN
Sbjct: 276 NPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLN 308


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 40/221 (18%), Positives = 84/221 (38%), Gaps = 10/221 (4%)

Query: 14  IESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVI-SSMPCLLMELRRDSSESQLA 72
           +E +      E+   +EE     L+  +++    D T+  +S+      ++ D++E++  
Sbjct: 88  VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT 147

Query: 73  STESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVS 132
             E    +    YE + +     S   +      +     +E E  + E    G   G +
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS-IGEN 206

Query: 133 GATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH--------KERIR 184
              V  + + + S+ ET  M+ K  + SS++      + +G     H        KER  
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266

Query: 185 LLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEE 225
             R + EA  R++    QD   +D     ++   ++  + E
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERE 307



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 36/194 (18%), Positives = 69/194 (35%), Gaps = 13/194 (6%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           +K E+     +E    EA  KA+ QE  + E    E   + +K    +   I        
Sbjct: 280 IKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAA 339

Query: 61  ELR-RDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQ 119
           E R R   E + A+ E  +        ++              + +       EE + + 
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399

Query: 120 AETAVEGDP--SGVSGATVGRKSR----------RSRSESETSTMAAKKNRQSSDKQNGR 167
            ET ++G+     + G  V  K            + + E + + + AK+ +   DK   +
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK 459

Query: 168 VAKVKGHRSQKHKE 181
             ++K  + +K KE
Sbjct: 460 KEEIKDEKIKKDKE 473


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 53/207 (25%), Positives = 82/207 (39%), Gaps = 35/207 (16%)

Query: 69  SQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDP 128
           SQ    E  +  TG  Y +D+S     S ++ G   DS T+    E+   + ++  + D 
Sbjct: 499 SQGYKKEGREQGTGNSY-TDTSGPKETSSATPGR--DSKTIQKGSESGRGRQKSPAQSD- 554

Query: 129 SGVSGATVGRKSRRS-------------RSESETSTMAAKKNRQSSDKQNGRVAKVKGHR 175
           S     TVG+K  +              + ESET    A     S  K     A  KG R
Sbjct: 555 STTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK-----AATKGSR 609

Query: 176 SQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLT-CDSSTSSSDDDEEVSGSSKTIT 234
               K+  +     R  A +KKY     SS    ++   D+S+S SD+ E +  SS+T  
Sbjct: 610 KPNIKKESK--SSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT-- 665

Query: 235 AEIPGHLDPGFLASDKTSAGNAPLNEE 261
                   P +  S++T    + + EE
Sbjct: 666 --------PKYPESNRTPVKPSSVEEE 684



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 69/322 (21%), Positives = 121/322 (37%), Gaps = 51/322 (15%)

Query: 20  PKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSES---QLASTES 76
           PK +E+  A+E  G +++ES+   D      + SSMP    +     S     +  S  S
Sbjct: 567 PKKAEKAAAEEPRGGLKIESETPVD------LASSMPSSRHKAATKGSRKPNIKKESKSS 620

Query: 77  DKPTT-GRVYESDSSNHCMLSPSSSGHLADSDTLSS-AEENE----PSQAETAVEGDPSG 130
            +PT   + Y+S S      S   S  + ++DT SS ++E+E     SQ     E + + 
Sbjct: 621 PRPTAEKKKYKSTSK-----SSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTP 675

Query: 131 VSGATVGRKSR--RSRSESETSTMAAKKNRQSSDKQNGRVAKVKGH-----RSQKHKERI 183
           V  ++V  +    R R  S              D +   + K+  +       + +KE  
Sbjct: 676 VKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETE 735

Query: 184 RLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDP 243
               +K+     +K+        S+           ++DD   S S K  T         
Sbjct: 736 PPKGEKKNVP--EKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKT--------- 784

Query: 244 GFLASDKTSAGNAP-LNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGT 302
                DK SAG+ P  N E +  S+  E +++          P G V       +HGS  
Sbjct: 785 ----EDKNSAGHKPSSNRESSKQSAAKEKDLL--------PSPAGPVPSKDPKTEHGSRK 832

Query: 303 QYVSTRQTQSWTAVTPQQTWAS 324
           + +S   +   ++ + ++T  S
Sbjct: 833 RTISQSSSLKSSSNSNKETSGS 854



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 17/106 (16%)

Query: 19  PPKASEQETAKEE-DGSVELESQVQKDGV--ADSTVISSMPCLLMELRRDSSESQLASTE 75
           P K S    +K      ++L S    DG    D T+  S P          S S+ +   
Sbjct: 367 PSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTP---------GSNSEPSHHN 417

Query: 76  SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSS-AEENEPSQA 120
           S+     R    DSS+H   S SSSG  ++S++ SS +E NEPSQ+
Sbjct: 418 SEGADNSR---DDSSSHSG-SESSSGSDSESESSSSDSEANEPSQS 459


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 56/222 (25%), Positives = 87/222 (39%), Gaps = 30/222 (13%)

Query: 124 VEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSD----------KQNGR----VA 169
           V+ +  G+SG     ++RRSR    T     KK   S D          + +GR     A
Sbjct: 5   VKEEDDGLSGKH-SMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAA 63

Query: 170 KVKGHRSQKHKERIRLLRQKREAAARKKYNLLQD----SSTSDSDLTCDSST-------- 217
               + S+    +    + K EA++  K N  Q     S T ++D T    T        
Sbjct: 64  STSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRP 123

Query: 218 SSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQ 277
           +S  + E  S  S+++  E  G  DP  +  D  S   +  + + N + SDS  +   +Q
Sbjct: 124 NSPSEGEGESSDSRSVNDE--GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 181

Query: 278 EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQ 319
                +    GV  + SS   G+  Q  +   T S TAV PQ
Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGT-PQLPTPGPTPSATAVPPQ 222


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 56/222 (25%), Positives = 87/222 (39%), Gaps = 30/222 (13%)

Query: 124 VEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSD----------KQNGR----VA 169
           V+ +  G+SG     ++RRSR    T     KK   S D          + +GR     A
Sbjct: 559 VKEEDDGLSGKH-SMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAA 617

Query: 170 KVKGHRSQKHKERIRLLRQKREAAARKKYNLLQD----SSTSDSDLTCDSST-------- 217
               + S+    +    + K EA++  K N  Q     S T ++D T    T        
Sbjct: 618 STSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRP 677

Query: 218 SSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQ 277
           +S  + E  S  S+++  E  G  DP  +  D  S   +  + + N + SDS  +   +Q
Sbjct: 678 NSPSEGEGESSDSRSVNDE--GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735

Query: 278 EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQ 319
                +    GV  + SS   G+  Q  +   T S TAV PQ
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGT-PQLPTPGPTPSATAVPPQ 776


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 56/222 (25%), Positives = 87/222 (39%), Gaps = 30/222 (13%)

Query: 124 VEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSD----------KQNGR----VA 169
           V+ +  G+SG     ++RRSR    T     KK   S D          + +GR     A
Sbjct: 559 VKEEDDGLSGKH-SMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAA 617

Query: 170 KVKGHRSQKHKERIRLLRQKREAAARKKYNLLQD----SSTSDSDLTCDSST-------- 217
               + S+    +    + K EA++  K N  Q     S T ++D T    T        
Sbjct: 618 STSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRP 677

Query: 218 SSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQ 277
           +S  + E  S  S+++  E  G  DP  +  D  S   +  + + N + SDS  +   +Q
Sbjct: 678 NSPSEGEGESSDSRSVNDE--GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735

Query: 278 EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQ 319
                +    GV  + SS   G+  Q  +   T S TAV PQ
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGT-PQLPTPGPTPSATAVPPQ 776


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 46/200 (23%), Positives = 85/200 (42%), Gaps = 16/200 (8%)

Query: 66   SSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLA-DSDTLSSAEENEPSQAETAV 124
            S +S   ++ES    +  V +   S H   SPS    +       SS E   P  A +  
Sbjct: 1371 SVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKN 1430

Query: 125  EGDPSGVSGATVGRKS-------------RRSRSESETSTMAAKKNRQSSDKQNGRVAKV 171
             G P  +SG+T   +              +   SESE+ +  A+K+ Q+S   +  +  +
Sbjct: 1431 YGSPL-ISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489

Query: 172  KGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSK 231
              + ++KHK+  +  ++ ++    +  +  +D   S S      S S    D+ +S +S 
Sbjct: 1490 PEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSN 1549

Query: 232  TI-TAEIPGHLDPGFLASDK 250
            TI +A+ P  L P F+  ++
Sbjct: 1550 TILSADRPSRLSPDFMIGEE 1569


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 35/140 (25%), Positives = 65/140 (46%), Gaps = 10/140 (7%)

Query: 65  DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAV 124
           DSS S   S + +K    R       N    S  SS H ++S++  S ++ + S+ ET  
Sbjct: 112 DSSSSSSDSEDEEKKQGKR--RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEK 169

Query: 125 EGDPSGVSG----ATVGRKSRRSRSESETS---TMAAKKNRQSSDKQNGRVAKVKGHRSQ 177
           E D   +S     +    K   S S SE+     + AKK R+  +++  +  KVK  + +
Sbjct: 170 EKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAK-EKVKKKKKK 228

Query: 178 KHKERIRLLRQKREAAARKK 197
           +HK+  +  ++K  ++ + +
Sbjct: 229 QHKKHSKKKKKKSGSSHKSR 248



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 21/160 (13%)

Query: 66  SSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
           S E  L+  ES      R  +    + C  S SSS     SD+ SS+ ++E  + +    
Sbjct: 76  SREKLLSGNESSSKKRERKKKRKKKS-CRSSSSSSS----SDSSSSSSDSEDEEKKQ--- 127

Query: 126 GDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRL 185
                      G++ ++ ++ S  S+ ++    +S  K++ +  K     ++K K+ +R 
Sbjct: 128 -----------GKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKD-VRS 175

Query: 186 LRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEE 225
           L +KR+ +      L  +SS S+SD   D         EE
Sbjct: 176 LSKKRKKSYPDDKPLSSESS-SESDYEEDVQAKKKRRCEE 214



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 144 RSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLR------QKREAAARKK 197
           + + E     +K   +  +K N      +  + +  K R +LL       +KRE   ++K
Sbjct: 45  KKQLENKKTGSKALAEFEEKMN------ENWKKELEKSREKLLSGNESSSKKRERKKKRK 98

Query: 198 YNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSK 231
               + SS+S S    DSS+SSSD ++E     K
Sbjct: 99  KKSCRSSSSSSSS---DSSSSSSDSEDEEKKQGK 129


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 50/221 (22%), Positives = 88/221 (39%), Gaps = 26/221 (11%)

Query: 21  KASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSS-ESQLASTESDKP 79
           + SE++   E D +  +E +V+ D   +S   +S    L + RRDS  +SQ  S E+   
Sbjct: 272 RISEEDDRSELDDNNTME-EVKSDSTENS---NSRDTGLSQPRRDSKGDSQEDSKENLSQ 327

Query: 80  TTGRVYE---SDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA-- 134
              +  +   S+SS    LS   +   +  + +S +  + P    + VE      S    
Sbjct: 328 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 387

Query: 135 ---TVGRKSRRSRSE------SETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRL 185
              T+      SR E      SE+   + +      D+ +     ++ H S         
Sbjct: 388 SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAES----- 442

Query: 186 LRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEV 226
             Q  E+ + +  +  QDSS S  D     S SSS++D ++
Sbjct: 443 --QSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQL 481



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 11/158 (6%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           ES      S QE + E    V  ES+        S V             DSSE   + T
Sbjct: 339 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDS-------DSSEEDSSHT 391

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            S   +  R  ++DS +   L+ S     +  D  SS++E   S + +A        S  
Sbjct: 392 LSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE 451

Query: 135 TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVK 172
                   SRS+ ++++  +K    SS +++G++  ++
Sbjct: 452 DDSDSQDSSRSKEDSNSTESK----SSSEEDGQLKNIE 485


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 50/221 (22%), Positives = 88/221 (39%), Gaps = 26/221 (11%)

Query: 21  KASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSS-ESQLASTESDKP 79
           + SE++   E D +  +E +V+ D   +S   +S    L + RRDS  +SQ  S E+   
Sbjct: 256 RISEEDDRSELDDNNTME-EVKSDSTENS---NSRDTGLSQPRRDSKGDSQEDSKENLSQ 311

Query: 80  TTGRVYE---SDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA-- 134
              +  +   S+SS    LS   +   +  + +S +  + P    + VE      S    
Sbjct: 312 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 371

Query: 135 ---TVGRKSRRSRSE------SETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRL 185
              T+      SR E      SE+   + +      D+ +     ++ H S         
Sbjct: 372 SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAES----- 426

Query: 186 LRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEV 226
             Q  E+ + +  +  QDSS S  D     S SSS++D ++
Sbjct: 427 --QSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQL 465



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 11/158 (6%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           ES      S QE + E    V  ES+        S V             DSSE   + T
Sbjct: 323 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDS-------DSSEEDSSHT 375

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            S   +  R  ++DS +   L+ S     +  D  SS++E   S + +A        S  
Sbjct: 376 LSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE 435

Query: 135 TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVK 172
                   SRS+ ++++  +K    SS +++G++  ++
Sbjct: 436 DDSDSQDSSRSKEDSNSTESK----SSSEEDGQLKNIE 469


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 32/185 (17%)

Query: 37   LESQVQKDGVADSTVISSMPCLLMELR-------------RDSSESQLASTESDKPTTGR 83
            L S V +D  A S V+SSMP    E               +D+ E    +   DK    +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816

Query: 84   VYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRS 143
              +S   +    S SS  H +   T  S        +++                KS RS
Sbjct: 1817 KRDSSLRSRSKRSKSSE-HKSRKRTSESRSRARKRSSKS----------------KSHRS 1859

Query: 144  RSESETSTMAAKKNRQSSDKQNGR--VAKVKGHRSQKHKERIRLLRQKREAAARKKYNLL 201
            ++ S + +   +++ +S  K  GR  V+K K  RS KH+ + R  ++KR ++   +  + 
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919

Query: 202  QDSST 206
              S T
Sbjct: 1920 ARSRT 1924


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 32/185 (17%)

Query: 37   LESQVQKDGVADSTVISSMPCLLMELR-------------RDSSESQLASTESDKPTTGR 83
            L S V +D  A S V+SSMP    E               +D+ E    +   DK    +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816

Query: 84   VYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRS 143
              +S   +    S SS  H +   T  S        +++                KS RS
Sbjct: 1817 KRDSSLRSRSKRSKSSE-HKSRKRTSESRSRARKRSSKS----------------KSHRS 1859

Query: 144  RSESETSTMAAKKNRQSSDKQNGR--VAKVKGHRSQKHKERIRLLRQKREAAARKKYNLL 201
            ++ S + +   +++ +S  K  GR  V+K K  RS KH+ + R  ++KR ++   +  + 
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919

Query: 202  QDSST 206
              S T
Sbjct: 1920 ARSRT 1924


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 52/279 (18%), Positives = 107/279 (38%), Gaps = 20/279 (7%)

Query: 47  ADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADS 106
           +++T +S+       +    SE+  AST   + T      S+++        ++   A S
Sbjct: 192 SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251

Query: 107 DTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS----- 161
           +T  +A   E S+  TA   D    + +T G ++  + +     TMA+    +++     
Sbjct: 252 ET--TAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTI 309

Query: 162 DKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSD 221
             +  +V+      +         +R     +     +     +T+ S +  ++ST S+ 
Sbjct: 310 GPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTT 369

Query: 222 DDEEVSGS---SKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQE 278
             E  + S   S+T TA   G        S+ T+      +E   ++ +DSE       E
Sbjct: 370 GSETTTASTEGSETTTASTEG--------SEATTVSTTG-SETTTVSITDSETTTT-CTE 419

Query: 279 HARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            +        V ++ ++   GS     ST  +++ TA T
Sbjct: 420 GSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 53/257 (20%), Positives = 91/257 (35%), Gaps = 31/257 (12%)

Query: 65   DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAET 122
            + SE+  ASTE  + TT     S+++    +   ++    +    T +S E +E + A T
Sbjct: 849  EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908

Query: 123  AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
              EG        T    +  S   SET+T + + +  ++    G              E 
Sbjct: 909  --EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-------------SET 953

Query: 183  IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH-- 240
            I +  +  E            + T+    T  +ST+ S+     +  S+T TA I G   
Sbjct: 954  ITVSAEGSETT----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 241  LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS 300
                   S+ T+         I          +         V+  G    + S+   GS
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST--EGS 1061

Query: 301  GTQYVSTRQTQSWTAVT 317
             T  VST  +++ TA T
Sbjct: 1062 ETTTVSTTGSETTTAST 1078



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 60/268 (22%), Positives = 106/268 (39%), Gaps = 46/268 (17%)

Query: 67  SESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEG 126
           SE+   ST   + TT  +  S++S     + S++G      T +S E +E + A T  EG
Sbjct: 341 SETTTVSTTGSETTTASIMGSETS-----TDSTTG---SETTTASTEGSETTTAST--EG 390

Query: 127 DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLL 186
             +     T    +  S ++SET+T   + +  ++                         
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT--------------------- 429

Query: 187 RQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFL 246
                  A  + + +  +STSDS+ T  +ST  S+     +  S+T TA   G       
Sbjct: 430 -VFETTTASTEGSEITIASTSDSE-TTTASTEGSETTTVTTAGSETKTAYTTG------- 480

Query: 247 ASDKTSAGNAPLNEEINIASSDSEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYV 305
            S+ T+A N  L E   + +  S+      +      V   G  + +VS+   GS    V
Sbjct: 481 -SETTTASNTGL-ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST--EGSENTTV 536

Query: 306 STRQTQSWT-AVTPQQTWASPAEVVDLT 332
           ST  +++ T + T  +T  +  E  ++T
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMT 564



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 59/290 (20%), Positives = 110/290 (37%), Gaps = 43/290 (14%)

Query: 38  ESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSP 97
           E+ V  +G + +T +S       ++    SE+   STE  + TT  +  S++        
Sbjct: 682 ETTVSTEG-SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET-------- 732

Query: 98  SSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKN 157
                     T +S E +E + A T  EG  +  S +T G ++  + + S  +TMA+   
Sbjct: 733 ----------TTASTEGSETTTAST--EGSET-TSASTTGSETTTASTTSSETTMASIMG 779

Query: 158 RQS---------SDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSD 208
            ++         + K +   +K+    ++  +  I               +    +ST+ 
Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG 839

Query: 209 SDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSD 268
           S+ T  +ST  S+     +  S+T TA            S +T+      +E    ++  
Sbjct: 840 SETTTTTSTEGSETTTASTEGSETTTAS---------TESSETTTATTIGSETTTASTEG 890

Query: 269 SEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
           SE      +          G  I +VS+   GS T   ST  +++ TA T
Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVST--TGSETTTASTEGSETTTAST 938



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 26/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 205 STSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINI 264
           S   S+ T +S+TSS       +GS  T  + +       + A  +T+A +   +E   +
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 265 ASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            ++ SE            + P     ++ +    GS T  VST  +++ TA T
Sbjct: 178 FTAGSET-----------ITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST 219



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 64/308 (20%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 46  VADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCML-----SPSSS 100
           V ++T  S+    +       SE+  ASTE  + TT     S++           + S++
Sbjct: 430 VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 489

Query: 101 G------HLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRR-SRSESETSTMA 153
           G          SDT +++ E   + A +A   + + VS  T G ++   S + SET+T++
Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS--TEGSENTTVSTTGSETTTVS 547

Query: 154 AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTC 213
                 ++    G  +++    +   +            AA    +     ST+DS+ T 
Sbjct: 548 TTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 214 DSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEI 273
            S+  S       +GS  T  +            S +T+  +   +E   ++++DSE  +
Sbjct: 606 ASTADSETTSASTTGSETTTAS----------TTSSETTTASTEGSETTTVSTTDSETTM 655

Query: 274 VGVQEHARCV-HPRGGVIQSVSSW-------KHGSGTQYVS-TRQTQSWTAVTPQQTWAS 324
           V      R +    G    +VS+          GSGT  VS T    +  + T  +T  +
Sbjct: 656 VSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTT 715

Query: 325 PAEVVDLT 332
             E  ++T
Sbjct: 716 STEGSEIT 723



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 56/325 (17%), Positives = 114/325 (35%), Gaps = 29/325 (8%)

Query: 18   APPKASEQETAKEEDGSVELESQVQKDGV------ADSTVISSMPCLLMELRRDSSESQL 71
            A  + SE  TA  E   +   S    + +      +++T +++M           SE+  
Sbjct: 926  ASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT 985

Query: 72   ASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGV 131
             ST   + TT  +  S+++     + S +  ++ + T ++    E S+  T         
Sbjct: 986  VSTAGSETTTASIEGSETTT-VSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044

Query: 132  SGATVGRKSRRSRSE-SETSTM---------AAKKNRQSSDKQNGRVAKVKGHRSQKHKE 181
            +  T G ++  + +E SET+T+         A+  + +++              +     
Sbjct: 1045 AVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETT 1104

Query: 182  RIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHL 241
             + +   K   A           ST  S+ T  S+TSS       +GS  T         
Sbjct: 1105 TVYITGSKTTTA-----------STEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSET 1153

Query: 242  DPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSG 301
                    + +  +A  +E    ++  SE                 G  ++ ++   GS 
Sbjct: 1154 TTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-SETTTASTAGSE 1212

Query: 302  TQYVSTRQTQSWTAVTPQQTWASPA 326
            T   ST  +++ TA T     ++P+
Sbjct: 1213 TTTASTSGSETNTACTTGSETSTPS 1237



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 40/168 (23%), Positives = 65/168 (38%), Gaps = 18/168 (10%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGV-ADSTVISSMPCLLMELRRDSSESQLAS 73
            E+     AS + TA    GS      +   G  A ST +SS   +L +          A+
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK----------AT 1301

Query: 74   TESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAETAVEGDPSGV 131
              S +P T        +    L+ SSS  +A     T S+A    P      +  + SG+
Sbjct: 1302 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPG-----IVLNTSGL 1356

Query: 132  SGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH 179
              +T+G  S  S     T+T + ++   S+ ++ G V+      S  H
Sbjct: 1357 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSH 1404


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 52/279 (18%), Positives = 107/279 (38%), Gaps = 20/279 (7%)

Query: 47  ADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADS 106
           +++T +S+       +    SE+  AST   + T      S+++        ++   A S
Sbjct: 192 SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251

Query: 107 DTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS----- 161
           +T  +A   E S+  TA   D    + +T G ++  + +     TMA+    +++     
Sbjct: 252 ET--TAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTI 309

Query: 162 DKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSD 221
             +  +V+      +         +R     +     +     +T+ S +  ++ST S+ 
Sbjct: 310 GPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTT 369

Query: 222 DDEEVSGS---SKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQE 278
             E  + S   S+T TA   G        S+ T+      +E   ++ +DSE       E
Sbjct: 370 GSETTTASTEGSETTTASTEG--------SEATTVSTTG-SETTTVSITDSETTTT-CTE 419

Query: 279 HARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            +        V ++ ++   GS     ST  +++ TA T
Sbjct: 420 GSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 53/257 (20%), Positives = 91/257 (35%), Gaps = 31/257 (12%)

Query: 65   DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAET 122
            + SE+  ASTE  + TT     S+++    +   ++    +    T +S E +E + A T
Sbjct: 849  EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908

Query: 123  AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
              EG        T    +  S   SET+T + + +  ++    G              E 
Sbjct: 909  --EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-------------SET 953

Query: 183  IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH-- 240
            I +  +  E            + T+    T  +ST+ S+     +  S+T TA I G   
Sbjct: 954  ITVSAEGSETT----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 241  LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS 300
                   S+ T+         I          +         V+  G    + S+   GS
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST--EGS 1061

Query: 301  GTQYVSTRQTQSWTAVT 317
             T  VST  +++ TA T
Sbjct: 1062 ETTTVSTTGSETTTAST 1078



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 60/268 (22%), Positives = 106/268 (39%), Gaps = 46/268 (17%)

Query: 67  SESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEG 126
           SE+   ST   + TT  +  S++S     + S++G      T +S E +E + A T  EG
Sbjct: 341 SETTTVSTTGSETTTASIMGSETS-----TDSTTG---SETTTASTEGSETTTAST--EG 390

Query: 127 DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLL 186
             +     T    +  S ++SET+T   + +  ++                         
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT--------------------- 429

Query: 187 RQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFL 246
                  A  + + +  +STSDS+ T  +ST  S+     +  S+T TA   G       
Sbjct: 430 -VFETTTASTEGSEITIASTSDSE-TTTASTEGSETTTVTTAGSETKTAYTTG------- 480

Query: 247 ASDKTSAGNAPLNEEINIASSDSEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYV 305
            S+ T+A N  L E   + +  S+      +      V   G  + +VS+   GS    V
Sbjct: 481 -SETTTASNTGL-ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST--EGSENTTV 536

Query: 306 STRQTQSWT-AVTPQQTWASPAEVVDLT 332
           ST  +++ T + T  +T  +  E  ++T
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMT 564



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 59/290 (20%), Positives = 110/290 (37%), Gaps = 43/290 (14%)

Query: 38  ESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSP 97
           E+ V  +G + +T +S       ++    SE+   STE  + TT  +  S++        
Sbjct: 682 ETTVSTEG-SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET-------- 732

Query: 98  SSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKN 157
                     T +S E +E + A T  EG  +  S +T G ++  + + S  +TMA+   
Sbjct: 733 ----------TTASTEGSETTTAST--EGSET-TSASTTGSETTTASTTSSETTMASIMG 779

Query: 158 RQS---------SDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSD 208
            ++         + K +   +K+    ++  +  I               +    +ST+ 
Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG 839

Query: 209 SDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSD 268
           S+ T  +ST  S+     +  S+T TA            S +T+      +E    ++  
Sbjct: 840 SETTTTTSTEGSETTTASTEGSETTTAS---------TESSETTTATTIGSETTTASTEG 890

Query: 269 SEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
           SE      +          G  I +VS+   GS T   ST  +++ TA T
Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVST--TGSETTTASTEGSETTTAST 938



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 26/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 205 STSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINI 264
           S   S+ T +S+TSS       +GS  T  + +       + A  +T+A +   +E   +
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 265 ASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            ++ SE            + P     ++ +    GS T  VST  +++ TA T
Sbjct: 178 FTAGSET-----------ITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST 219



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 64/308 (20%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 46  VADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCML-----SPSSS 100
           V ++T  S+    +       SE+  ASTE  + TT     S++           + S++
Sbjct: 430 VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 489

Query: 101 G------HLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRR-SRSESETSTMA 153
           G          SDT +++ E   + A +A   + + VS  T G ++   S + SET+T++
Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS--TEGSENTTVSTTGSETTTVS 547

Query: 154 AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTC 213
                 ++    G  +++    +   +            AA    +     ST+DS+ T 
Sbjct: 548 TTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 214 DSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEI 273
            S+  S       +GS  T  +            S +T+  +   +E   ++++DSE  +
Sbjct: 606 ASTADSETTSASTTGSETTTAS----------TTSSETTTASTEGSETTTVSTTDSETTM 655

Query: 274 VGVQEHARCV-HPRGGVIQSVSSW-------KHGSGTQYVS-TRQTQSWTAVTPQQTWAS 324
           V      R +    G    +VS+          GSGT  VS T    +  + T  +T  +
Sbjct: 656 VSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTT 715

Query: 325 PAEVVDLT 332
             E  ++T
Sbjct: 716 STEGSEIT 723



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 4/103 (3%)

Query: 66   SSESQLASTESDKPTTGRVYESDSSNHCML-SPSSSGHLADSD-TLSSAEENEPSQAETA 123
            SSE+  AST   + TT     S+++    + S +++   A S+ T +S E +E + A TA
Sbjct: 1130 SSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189

Query: 124  VEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNG 166
              G  +  +       +  S S SET+T     +  S+    G
Sbjct: 1190 --GSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1230



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 40/168 (23%), Positives = 65/168 (38%), Gaps = 18/168 (10%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGV-ADSTVISSMPCLLMELRRDSSESQLAS 73
            E+     AS + TA    GS      +   G  A ST +SS   +L +          A+
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK----------AT 1291

Query: 74   TESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAETAVEGDPSGV 131
              S +P T        +    L+ SSS  +A     T S+A    P      +  + SG+
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPG-----IVLNTSGL 1346

Query: 132  SGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH 179
              +T+G  S  S     T+T + ++   S+ ++ G V+      S  H
Sbjct: 1347 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSH 1394


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 52/279 (18%), Positives = 107/279 (38%), Gaps = 20/279 (7%)

Query: 47  ADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADS 106
           +++T +S+       +    SE+  AST   + T      S+++        ++   A S
Sbjct: 192 SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251

Query: 107 DTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS----- 161
           +T  +A   E S+  TA   D    + +T G ++  + +     TMA+    +++     
Sbjct: 252 ET--TAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTI 309

Query: 162 DKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSD 221
             +  +V+      +         +R     +     +     +T+ S +  ++ST S+ 
Sbjct: 310 GPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTT 369

Query: 222 DDEEVSGS---SKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQE 278
             E  + S   S+T TA   G        S+ T+      +E   ++ +DSE       E
Sbjct: 370 GSETTTASTEGSETTTASTEG--------SEATTVSTTG-SETTTVSITDSETTTT-CTE 419

Query: 279 HARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            +        V ++ ++   GS     ST  +++ TA T
Sbjct: 420 GSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 53/257 (20%), Positives = 91/257 (35%), Gaps = 31/257 (12%)

Query: 65   DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAET 122
            + SE+  ASTE  + TT     S+++    +   ++    +    T +S E +E + A T
Sbjct: 849  EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908

Query: 123  AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
              EG        T    +  S   SET+T + + +  ++    G              E 
Sbjct: 909  --EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-------------SET 953

Query: 183  IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH-- 240
            I +  +  E            + T+    T  +ST+ S+     +  S+T TA I G   
Sbjct: 954  ITVSAEGSETT----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 241  LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS 300
                   S+ T+         I          +         V+  G    + S+   GS
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST--EGS 1061

Query: 301  GTQYVSTRQTQSWTAVT 317
             T  VST  +++ TA T
Sbjct: 1062 ETTTVSTTGSETTTAST 1078



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 60/268 (22%), Positives = 106/268 (39%), Gaps = 46/268 (17%)

Query: 67  SESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEG 126
           SE+   ST   + TT  +  S++S     + S++G      T +S E +E + A T  EG
Sbjct: 341 SETTTVSTTGSETTTASIMGSETS-----TDSTTG---SETTTASTEGSETTTAST--EG 390

Query: 127 DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLL 186
             +     T    +  S ++SET+T   + +  ++                         
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT--------------------- 429

Query: 187 RQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFL 246
                  A  + + +  +STSDS+ T  +ST  S+     +  S+T TA   G       
Sbjct: 430 -VFETTTASTEGSEITIASTSDSE-TTTASTEGSETTTVTTAGSETKTAYTTG------- 480

Query: 247 ASDKTSAGNAPLNEEINIASSDSEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYV 305
            S+ T+A N  L E   + +  S+      +      V   G  + +VS+   GS    V
Sbjct: 481 -SETTTASNTGL-ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST--EGSENTTV 536

Query: 306 STRQTQSWT-AVTPQQTWASPAEVVDLT 332
           ST  +++ T + T  +T  +  E  ++T
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMT 564



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 59/290 (20%), Positives = 110/290 (37%), Gaps = 43/290 (14%)

Query: 38  ESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSP 97
           E+ V  +G + +T +S       ++    SE+   STE  + TT  +  S++        
Sbjct: 682 ETTVSTEG-SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET-------- 732

Query: 98  SSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKN 157
                     T +S E +E + A T  EG  +  S +T G ++  + + S  +TMA+   
Sbjct: 733 ----------TTASTEGSETTTAST--EGSET-TSASTTGSETTTASTTSSETTMASIMG 779

Query: 158 RQS---------SDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSD 208
            ++         + K +   +K+    ++  +  I               +    +ST+ 
Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG 839

Query: 209 SDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSD 268
           S+ T  +ST  S+     +  S+T TA            S +T+      +E    ++  
Sbjct: 840 SETTTTTSTEGSETTTASTEGSETTTAS---------TESSETTTATTIGSETTTASTEG 890

Query: 269 SEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
           SE      +          G  I +VS+   GS T   ST  +++ TA T
Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVST--TGSETTTASTEGSETTTAST 938



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 26/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 205 STSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINI 264
           S   S+ T +S+TSS       +GS  T  + +       + A  +T+A +   +E   +
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 265 ASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            ++ SE            + P     ++ +    GS T  VST  +++ TA T
Sbjct: 178 FTAGSET-----------ITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST 219



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 64/308 (20%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 46  VADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCML-----SPSSS 100
           V ++T  S+    +       SE+  ASTE  + TT     S++           + S++
Sbjct: 430 VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 489

Query: 101 G------HLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRR-SRSESETSTMA 153
           G          SDT +++ E   + A +A   + + VS  T G ++   S + SET+T++
Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS--TEGSENTTVSTTGSETTTVS 547

Query: 154 AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTC 213
                 ++    G  +++    +   +            AA    +     ST+DS+ T 
Sbjct: 548 TTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 214 DSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEI 273
            S+  S       +GS  T  +            S +T+  +   +E   ++++DSE  +
Sbjct: 606 ASTADSETTSASTTGSETTTAS----------TTSSETTTASTEGSETTTVSTTDSETTM 655

Query: 274 VGVQEHARCV-HPRGGVIQSVSSW-------KHGSGTQYVS-TRQTQSWTAVTPQQTWAS 324
           V      R +    G    +VS+          GSGT  VS T    +  + T  +T  +
Sbjct: 656 VSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTT 715

Query: 325 PAEVVDLT 332
             E  ++T
Sbjct: 716 STEGSEIT 723



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 18/168 (10%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGV-ADSTVISSMPCLLMELRRDSSESQLAS 73
            ES     AS + TA    GS      +   G  A ST +SS   +L +          A+
Sbjct: 1242 ESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK----------AT 1291

Query: 74   TESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAETAVEGDPSGV 131
              S +P T        +    L+ SSS  +A     T S+A    P      +  + SG+
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPG-----IVLNTSGL 1346

Query: 132  SGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH 179
              +T+G  S  S     T+T + ++   S+ ++ G V+      S  H
Sbjct: 1347 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSH 1394



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 4/103 (3%)

Query: 66   SSESQLASTESDKPTTGRVYESDSSNHCML-SPSSSGHLADSD-TLSSAEENEPSQAETA 123
            SSE+  AST   + TT     S+++    + S +++   A S+ T +S E +E + A TA
Sbjct: 1130 SSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189

Query: 124  VEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNG 166
              G  +  +       +  S S SET+T     +  S+    G
Sbjct: 1190 --GSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1230


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 52/279 (18%), Positives = 107/279 (38%), Gaps = 20/279 (7%)

Query: 47  ADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADS 106
           +++T +S+       +    SE+  AST   + T      S+++        ++   A S
Sbjct: 213 SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 272

Query: 107 DTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS----- 161
           +T  +A   E S+  TA   D    + +T G ++  + +     TMA+    +++     
Sbjct: 273 ET--TAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTI 330

Query: 162 DKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSD 221
             +  +V+      +         +R     +     +     +T+ S +  ++ST S+ 
Sbjct: 331 GPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTT 390

Query: 222 DDEEVSGS---SKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQE 278
             E  + S   S+T TA   G        S+ T+      +E   ++ +DSE       E
Sbjct: 391 GSETTTASTEGSETTTASTEG--------SEATTVSTTG-SETTTVSITDSETTTT-CTE 440

Query: 279 HARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            +        V ++ ++   GS     ST  +++ TA T
Sbjct: 441 GSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 479



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 53/257 (20%), Positives = 91/257 (35%), Gaps = 31/257 (12%)

Query: 65   DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAET 122
            + SE+  ASTE  + TT     S+++    +   ++    +    T +S E +E + A T
Sbjct: 870  EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 929

Query: 123  AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
              EG        T    +  S   SET+T + + +  ++    G              E 
Sbjct: 930  --EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-------------SET 974

Query: 183  IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH-- 240
            I +  +  E            + T+    T  +ST+ S+     +  S+T TA I G   
Sbjct: 975  ITVSAEGSETT----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1024

Query: 241  LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS 300
                   S+ T+         I          +         V+  G    + S+   GS
Sbjct: 1025 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST--EGS 1082

Query: 301  GTQYVSTRQTQSWTAVT 317
             T  VST  +++ TA T
Sbjct: 1083 ETTTVSTTGSETTTAST 1099



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 60/268 (22%), Positives = 106/268 (39%), Gaps = 46/268 (17%)

Query: 67  SESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEG 126
           SE+   ST   + TT  +  S++S     + S++G      T +S E +E + A T  EG
Sbjct: 362 SETTTVSTTGSETTTASIMGSETS-----TDSTTG---SETTTASTEGSETTTAST--EG 411

Query: 127 DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLL 186
             +     T    +  S ++SET+T   + +  ++                         
Sbjct: 412 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT--------------------- 450

Query: 187 RQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFL 246
                  A  + + +  +STSDS+ T  +ST  S+     +  S+T TA   G       
Sbjct: 451 -VFETTTASTEGSEITIASTSDSE-TTTASTEGSETTTVTTAGSETKTAYTTG------- 501

Query: 247 ASDKTSAGNAPLNEEINIASSDSEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYV 305
            S+ T+A N  L E   + +  S+      +      V   G  + +VS+   GS    V
Sbjct: 502 -SETTTASNTGL-ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST--EGSENTTV 557

Query: 306 STRQTQSWT-AVTPQQTWASPAEVVDLT 332
           ST  +++ T + T  +T  +  E  ++T
Sbjct: 558 STTGSETTTVSTTGLETTTTSTEGSEMT 585



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 61/290 (21%), Positives = 103/290 (35%), Gaps = 64/290 (22%)

Query: 39  SQVQKDGVADSTVI--SSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCML- 95
           S+      ADS VI  SSM           S +  AST   + TT  +  S+++      
Sbjct: 4   SEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG 63

Query: 96  ----SPSSSGHLADSDTLSSAEENEPSQA---ETAVEGDPSGVSGATV-GRKSRRSRSES 147
               +PS +G      ++S +E    S A    T V    SG + A++ G +S  S + S
Sbjct: 64  SETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGS 123

Query: 148 ETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTS 207
           ET+T++      +     G                                         
Sbjct: 124 ETTTVSITGTETTMVSAMG----------------------------------------- 142

Query: 208 DSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASS 267
            S+ T +S+TSS       +GS  T  + +       + A  +T+A +   +E   + ++
Sbjct: 143 -SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 201

Query: 268 DSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            SE            + P     ++ +    GS T  VST  +++ TA T
Sbjct: 202 GSET-----------ITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST 240



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 59/290 (20%), Positives = 110/290 (37%), Gaps = 43/290 (14%)

Query: 38  ESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSP 97
           E+ V  +G + +T +S       ++    SE+   STE  + TT  +  S++        
Sbjct: 703 ETTVSTEG-SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET-------- 753

Query: 98  SSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKN 157
                     T +S E +E + A T  EG  +  S +T G ++  + + S  +TMA+   
Sbjct: 754 ----------TTASTEGSETTTAST--EGSET-TSASTTGSETTTASTTSSETTMASIMG 800

Query: 158 RQS---------SDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSD 208
            ++         + K +   +K+    ++  +  I               +    +ST+ 
Sbjct: 801 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG 860

Query: 209 SDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSD 268
           S+ T  +ST  S+     +  S+T TA            S +T+      +E    ++  
Sbjct: 861 SETTTTTSTEGSETTTASTEGSETTTAS---------TESSETTTATTIGSETTTASTEG 911

Query: 269 SEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
           SE      +          G  I +VS+   GS T   ST  +++ TA T
Sbjct: 912 SETTTTSTEGSETTTASTEGSEITTVST--TGSETTTASTEGSETTTAST 959



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 64/308 (20%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 46  VADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCML-----SPSSS 100
           V ++T  S+    +       SE+  ASTE  + TT     S++           + S++
Sbjct: 451 VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 510

Query: 101 G------HLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRR-SRSESETSTMA 153
           G          SDT +++ E   + A +A   + + VS  T G ++   S + SET+T++
Sbjct: 511 GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS--TEGSENTTVSTTGSETTTVS 568

Query: 154 AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTC 213
                 ++    G  +++    +   +            AA    +     ST+DS+ T 
Sbjct: 569 TTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 626

Query: 214 DSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEI 273
            S+  S       +GS  T  +            S +T+  +   +E   ++++DSE  +
Sbjct: 627 ASTADSETTSASTTGSETTTAS----------TTSSETTTASTEGSETTTVSTTDSETTM 676

Query: 274 VGVQEHARCV-HPRGGVIQSVSSW-------KHGSGTQYVS-TRQTQSWTAVTPQQTWAS 324
           V      R +    G    +VS+          GSGT  VS T    +  + T  +T  +
Sbjct: 677 VSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTT 736

Query: 325 PAEVVDLT 332
             E  ++T
Sbjct: 737 STEGSEIT 744



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 4/103 (3%)

Query: 66   SSESQLASTESDKPTTGRVYESDSSNHCML-SPSSSGHLADSD-TLSSAEENEPSQAETA 123
            SSE+  AST   + TT     S+++    + S +++   A S+ T +S E +E + A TA
Sbjct: 1151 SSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1210

Query: 124  VEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNG 166
              G  +  +       +  S S SET+T     +  S+    G
Sbjct: 1211 --GSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1251



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 40/168 (23%), Positives = 65/168 (38%), Gaps = 18/168 (10%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGV-ADSTVISSMPCLLMELRRDSSESQLAS 73
            E+     AS + TA    GS      +   G  A ST +SS   +L +          A+
Sbjct: 1263 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK----------AT 1312

Query: 74   TESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAETAVEGDPSGV 131
              S +P T        +    L+ SSS  +A     T S+A    P      +  + SG+
Sbjct: 1313 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPG-----IVLNTSGL 1367

Query: 132  SGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH 179
              +T+G  S  S     T+T + ++   S+ ++ G V+      S  H
Sbjct: 1368 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSH 1415


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 52/279 (18%), Positives = 107/279 (38%), Gaps = 20/279 (7%)

Query: 47  ADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADS 106
           +++T +S+       +    SE+  AST   + T      S+++        ++   A S
Sbjct: 192 SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251

Query: 107 DTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS----- 161
           +T  +A   E S+  TA   D    + +T G ++  + +     TMA+    +++     
Sbjct: 252 ET--TAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTI 309

Query: 162 DKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSD 221
             +  +V+      +         +R     +     +     +T+ S +  ++ST S+ 
Sbjct: 310 GPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTT 369

Query: 222 DDEEVSGS---SKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQE 278
             E  + S   S+T TA   G        S+ T+      +E   ++ +DSE       E
Sbjct: 370 GSETTTASTEGSETTTASTEG--------SEATTVSTTG-SETTTVSITDSETTTT-CTE 419

Query: 279 HARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            +        V ++ ++   GS     ST  +++ TA T
Sbjct: 420 GSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 53/257 (20%), Positives = 91/257 (35%), Gaps = 31/257 (12%)

Query: 65   DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAET 122
            + SE+  ASTE  + TT     S+++    +   ++    +    T +S E +E + A T
Sbjct: 849  EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908

Query: 123  AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
              EG        T    +  S   SET+T + + +  ++    G              E 
Sbjct: 909  --EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-------------SET 953

Query: 183  IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGH-- 240
            I +  +  E            + T+    T  +ST+ S+     +  S+T TA I G   
Sbjct: 954  ITVSAEGSETT----------TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 241  LDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGS 300
                   S+ T+         I          +         V+  G    + S+   GS
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST--EGS 1061

Query: 301  GTQYVSTRQTQSWTAVT 317
             T  VST  +++ TA T
Sbjct: 1062 ETTTVSTTGSETTTAST 1078



 Score = 35.0 bits (79), Expect = 0.098
 Identities = 47/233 (20%), Positives = 90/233 (38%), Gaps = 21/233 (9%)

Query: 47  ADSTVISSMPCLLMELRRDSSESQLASTESDK----PTTGRVYESDSSNHCMLSPSSSGH 102
           +++T +S+       +     E+   STE  +     TTG    +DS+     + +S+  
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 103 LADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS- 161
            +++ T+S+A+    S+  TA   D    S +T G ++  + + S  +T A+ +  +++ 
Sbjct: 591 -SETTTVSTAD----SENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 162 ----DKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSST 217
               D +   V       S    ER     +  E             ST  S  T  S T
Sbjct: 646 VSTTDSETTMV-------STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 218 SSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSE 270
            S       +GS  TIT+     +    +   +T+  +   +E    ++  SE
Sbjct: 699 GSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSE 751



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 59/290 (20%), Positives = 111/290 (38%), Gaps = 43/290 (14%)

Query: 38  ESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSP 97
           E+ V  +G + +T +S       ++    SE+ + STE  + TT  +  S++        
Sbjct: 682 ETTVSTEG-SGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSET-------- 732

Query: 98  SSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKN 157
                     T +S E +E + A T  EG  +  S +T G ++  + + S  +TMA+   
Sbjct: 733 ----------TTASTEGSETTTAST--EGSET-TSASTTGSETTTASTTSSETTMASIMG 779

Query: 158 RQS---------SDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSD 208
            ++         + K +   +K+    ++  +  I               +    +ST+ 
Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG 839

Query: 209 SDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSD 268
           S+ T  +ST  S+     +  S+T TA            S +T+      +E    ++  
Sbjct: 840 SETTTTTSTEGSETTTASTEGSETTTAS---------TESSETTTATTIGSETTTASTEG 890

Query: 269 SEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
           SE      +          G  I +VS+   GS T   ST  +++ TA T
Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVST--TGSETTTASTEGSETTTAST 938



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 60/268 (22%), Positives = 106/268 (39%), Gaps = 46/268 (17%)

Query: 67  SESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEG 126
           SE+   ST   + TT  +  S++S     + S++G      T +S E +E + A T  EG
Sbjct: 341 SETTTVSTTGSETTTASIMGSETS-----TDSTTG---SETTTASTEGSETTTAST--EG 390

Query: 127 DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLL 186
             +     T    +  S ++SET+T   + +  ++                         
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT--------------------- 429

Query: 187 RQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFL 246
                  A  + + +  +STSDS+ T  +ST  S+     +  S+T TA   G       
Sbjct: 430 -VFETTTASTEGSEITIASTSDSE-TTTASTEGSETTTVTTAGSETKTAYTTG------- 480

Query: 247 ASDKTSAGNAPLNEEINIASSDSEVEIVGVQ-EHARCVHPRGGVIQSVSSWKHGSGTQYV 305
            S+ T+A N  L E   + +  S+      +      V   G  + +VS+   GS    V
Sbjct: 481 -SETTTASNTGL-ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST--EGSENTTV 536

Query: 306 STRQTQSWT-AVTPQQTWASPAEVVDLT 332
           ST  +++ T + T  +T  +  E  ++T
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMT 564



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 26/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 205 STSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINI 264
           S   S+ T +S+TSS       +GS  T  + +       + A  +T+A +   +E   +
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 265 ASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 317
            ++ SE            + P     ++ +    GS T  VST  +++ TA T
Sbjct: 178 FTAGSET-----------ITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST 219



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 64/308 (20%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 46  VADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCML-----SPSSS 100
           V ++T  S+    +       SE+  ASTE  + TT     S++           + S++
Sbjct: 430 VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 489

Query: 101 G------HLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRR-SRSESETSTMA 153
           G          SDT +++ E   + A +A   + + VS  T G ++   S + SET+T++
Sbjct: 490 GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS--TEGSENTTVSTTGSETTTVS 547

Query: 154 AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTC 213
                 ++    G  +++    +   +            AA    +     ST+DS+ T 
Sbjct: 548 TTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 214 DSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEI 273
            S+  S       +GS  T  +            S +T+  +   +E   ++++DSE  +
Sbjct: 606 ASTADSETTSASTTGSETTTAS----------TTSSETTTASTEGSETTTVSTTDSETTM 655

Query: 274 VGVQEHARCV-HPRGGVIQSVSSW-------KHGSGTQYVS-TRQTQSWTAVTPQQTWAS 324
           V      R +    G    +VS+          GSGT  VS T    +  + T  +T  +
Sbjct: 656 VSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTIT 715

Query: 325 PAEVVDLT 332
             E  ++T
Sbjct: 716 STEGSEIT 723



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 4/103 (3%)

Query: 66   SSESQLASTESDKPTTGRVYESDSSNHCML-SPSSSGHLADSD-TLSSAEENEPSQAETA 123
            SSE+  AST   + TT     S+++    + S +++   A S+ T +S E +E + A TA
Sbjct: 1130 SSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189

Query: 124  VEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNG 166
              G  +  +       +  S S SET+T     +  S+    G
Sbjct: 1190 --GSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1230



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 40/168 (23%), Positives = 65/168 (38%), Gaps = 18/168 (10%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGV-ADSTVISSMPCLLMELRRDSSESQLAS 73
            E+     AS + TA    GS      +   G  A ST +SS   +L +          A+
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK----------AT 1291

Query: 74   TESDKPTTGRVYESDSSNHCMLSPSSSGHLADSD--TLSSAEENEPSQAETAVEGDPSGV 131
              S +P T        +    L+ SSS  +A     T S+A    P      +  + SG+
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPG-----IVLNTSGL 1346

Query: 132  SGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH 179
              +T+G  S  S     T+T + ++   S+ ++ G V+      S  H
Sbjct: 1347 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSH 1394


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.118    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,741,073
Number of Sequences: 37866
Number of extensions: 554357
Number of successful extensions: 4121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 332
Number of HSP's that attempted gapping in prelim test: 2865
Number of HSP's gapped (non-prelim): 1127
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.