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Search of human proteins with 13435127
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13435127 TRAF3-interacting JNK-activating modulator [Homo
sapiens]
(531 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13435127 TRAF3-interacting JNK-activating modulator [Homo sap... 1063 0.0
gi|56550043 sarcolemma associated protein [Homo sapiens] 153 3e-37
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 73 6e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 71 3e-12
gi|38044112 restin isoform b [Homo sapiens] 69 8e-12
gi|4506751 restin isoform a [Homo sapiens] 69 8e-12
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 69 1e-11
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 67 4e-11
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 67 5e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 66 9e-11
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 65 1e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 65 1e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 65 1e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 65 1e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 65 1e-10
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 65 2e-10
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 64 3e-10
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 64 3e-10
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 64 3e-10
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 64 3e-10
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 63 6e-10
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 62 1e-09
gi|4504063 golgin 97 [Homo sapiens] 62 1e-09
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 61 2e-09
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 61 2e-09
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 61 2e-09
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 61 2e-09
gi|32698688 citron [Homo sapiens] 61 3e-09
gi|156104908 myosin heavy chain 6 [Homo sapiens] 60 5e-09
gi|21735548 centrosomal protein 2 [Homo sapiens] 60 6e-09
>gi|13435127 TRAF3-interacting JNK-activating modulator [Homo
sapiens]
Length = 531
Score = 1063 bits (2749), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MISPDPRPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRA 60
MISPDPRPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRA
Sbjct: 1 MISPDPRPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRA 60
Query: 61 RLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICRDLSD 120
RLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICRDLSD
Sbjct: 61 RLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICRDLSD 120
Query: 121 HLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDY 180
HLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDY
Sbjct: 121 HLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDY 180
Query: 181 LKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKY 240
LKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKY
Sbjct: 181 LKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKY 240
Query: 241 SPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRS 300
SPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRS
Sbjct: 241 SPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRS 300
Query: 301 QYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC 360
QYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC
Sbjct: 301 QYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC 360
Query: 361 LQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQA 420
LQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQA
Sbjct: 361 LQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQA 420
Query: 421 LPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLS 480
LPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLS
Sbjct: 421 LPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLS 480
Query: 481 CLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVVIAAALAVFLANKDNLMI 531
CLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVVIAAALAVFLANKDNLMI
Sbjct: 481 CLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVVIAAALAVFLANKDNLMI 531
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 153 bits (387), Expect = 3e-37
Identities = 101/343 (29%), Positives = 177/343 (51%), Gaps = 18/343 (5%)
Query: 168 AVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLR 227
++ +E+ QLS YL+EAL RE +L+QK+ LQ LL+ +ASD+SW+ ++ED+L +L
Sbjct: 159 SMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLE 218
Query: 228 SLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRS 287
+ NQL C++ + ++K L+ +++ K++YE AKESL++VL+EK+ ++L +RS
Sbjct: 219 VMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERS 278
Query: 288 LALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQ----- 342
L+ E +C + E +E+ R L ++ +++ L KL+ A+ + ++ Q
Sbjct: 279 LSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAE 338
Query: 343 ------ALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQL 396
+ +E + Q+LQAKIE LQ D D + LQ+ L T + + +
Sbjct: 339 KKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIEC 398
Query: 397 Q-GLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTL 455
Q L+ L +E L+K++Q F + + P KEK D Q
Sbjct: 399 QKKLIVEGHLTKAVEETKLSKENQTRA--KESDFSDTLSP---SKEKSSDDTTDAQMDEQ 453
Query: 456 QLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQL 498
L + L +L E + +++QH R+EL ++Q+L
Sbjct: 454 DLNEPLAKVSLLKDDLQGAQSE-IEAKQEIQHLRKELIEAQEL 495
Score = 48.1 bits (113), Expect = 2e-05
Identities = 84/366 (22%), Positives = 159/366 (43%), Gaps = 51/366 (13%)
Query: 177 LSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKL----RSLENQ 232
L D L+ A Q E+ KQ+ +Q L LI+A + + + +L+ L ++ NQ
Sbjct: 465 LKDDLQGA-QSEIEAKQE---IQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQ 520
Query: 233 LYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLA-LA 291
+ T++ + L + D +N E+K E + +E ++A ++ ++ A +A
Sbjct: 521 VEESTKQIQVLQAQLQRLHI-DTENLREEKDSE-ITSTRDELLSARDEILLLHQAAAKVA 578
Query: 292 EQKCEEWRSQYEALK------EDWRTLGTQH-RELESQLHVLQSKLQGADSRDLQMNQAL 344
++ + S E LK E WR +++ +E+ S + Q + Q + D Q +A
Sbjct: 579 SERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCE--DQQREEAT 636
Query: 345 RF------LENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQG 398
R L E L+ + L+ + L S + Q + +L S+ + L L + + LQ
Sbjct: 637 RLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQM 696
Query: 399 L---LQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTL 455
L+NQ L+EQ +D A K+ ++ E + +K+++ + Q L
Sbjct: 697 SRKELENQVGSLKEQHL----RDSA----DLKTLLSKAENQAKDVQKEYE-KTQTVLSEL 747
Query: 456 QLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVVI 515
+L+ + E E +++DE C L+ RE+ N W+P+L ++
Sbjct: 748 KLKFEMTE-----QEKQSITDELKQCKNNLKLLREKGNNKP--------WPWMPMLAALV 794
Query: 516 AAALAV 521
A V
Sbjct: 795 AVTAIV 800
Score = 46.2 bits (108), Expect = 7e-05
Identities = 66/266 (24%), Positives = 110/266 (41%), Gaps = 56/266 (21%)
Query: 254 DQKNSYEQKAKESLQKV----LEEKMNAEQQLQSTQRSLALAE-------QKCEEWRSQY 302
D+++ E AK SL K + ++ A+Q++Q ++ L A+ QKC E ++
Sbjct: 451 DEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQA-- 508
Query: 303 EALKEDWRTLGTQHRELESQLHVLQSKLQGA--DSRDLQMNQALRFLENEHQQLQAKIEC 360
L+E+ + Q E Q+ VLQ++LQ D+ +L+ + + L A+ E
Sbjct: 509 -LLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDEI 567
Query: 361 L---------QGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE 411
L +RD D LQ++LK+ AE L+ E E
Sbjct: 568 LLLHQAAAKVASERDT---DIASLQEELKKVRAE--------------LERWRKAASEYE 610
Query: 412 KLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSEL 471
K +T + + + E +E+ L+ +L+K + A E EC L E
Sbjct: 611 KEITSLQNSFQLRCQQC-------EDQQREEATRLQGELEKLRKEWNALETECHSLKREN 663
Query: 472 DNLSDEYLSCLRKLQHCREELNQSQQ 497
LS E LQ +EL+ SQ+
Sbjct: 664 VLLSSE-------LQRQEKELHNSQK 682
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 73.2 bits (178), Expect = 6e-13
Identities = 100/519 (19%), Positives = 216/519 (41%), Gaps = 56/519 (10%)
Query: 7 RPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRA------ 60
R G RW E + +E +S++C+ ++ T + E ++ A
Sbjct: 76 RKRRGTKRWDEDDDL-----EESEDSKQCKESLKRV-----TFTLPDDEAIEDAGVSHVK 125
Query: 61 ----RLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICR 116
++ F++R ++ EK + + P R G+VT AQ P + +
Sbjct: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVT--------AQKRPENSLLE 177
Query: 117 DLS--DHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEI 174
+ DH + + G + T + P T + + +A Q + +K
Sbjct: 178 ETLHFDH-AVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSE 236
Query: 175 IQLS-DYLKEALQRELVL--KQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSL-- 229
IQL+ LK L+R +L +Q++ + D L +Q+ + + Q+ E++L L
Sbjct: 237 IQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE 296
Query: 230 -----------ENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAE 278
E + C Q+ ++ + E++ + E+K +E K+ ++
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR 356
Query: 279 QQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDL 338
+Q + + ++ E+ R Q E ++E + Q ++ Q Q K+ + +
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 339 QMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQG 398
+ ++ +R E E + + KI R+L + QD +++L+ E + ++Q+ +
Sbjct: 417 EQDEKIREQEEEMWRQEEKI------RELEEM-MQDQEEKLREVEEKMQEEEEKMQEQEE 469
Query: 399 LLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQ 458
+Q Q ++QEQE+ ++++ L + + E +EK W+ +++Q++ ++Q
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLK--QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQ 527
Query: 459 AKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
+E++ RE L ++ +LQ E L + Q
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566
Score = 44.3 bits (103), Expect = 3e-04
Identities = 71/362 (19%), Positives = 157/362 (43%), Gaps = 68/362 (18%)
Query: 148 TKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVI---LQDLLST 204
T E T + DA Y + D+E+ + + L+E L+ LV +K I ++DL
Sbjct: 190 TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLR--LVESEKSEIQLNVKDLKRK 247
Query: 205 LIQASDSSWKGQLN--EDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQK 262
L +A + QL D+L +L+S+ +L ++ W LL + ++ + Q+
Sbjct: 248 LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWN----LLNQQQEEKMWRQE 303
Query: 263 AKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQ 322
K Q EEKM EQ+L+ + EQ+ + WR E +
Sbjct: 304 EKIQEQ---EEKM-CEQELK-------IREQEEKMWRQ-------------------EEK 333
Query: 323 LHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS 382
+H + K++ + + + + +R E + ++ + K+ Q++ R
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW---------------RQEEKIRE 378
Query: 383 EAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEK 442
+ EK +Q+ + + Q +++EQE+ +K +W + E + + +E+
Sbjct: 379 QDEK------IQEQEEEMWRQEEKIREQEEKRQEK-----MWRQEKKMREQDEKIREQEE 427
Query: 443 D-WDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPR 501
+ W +++++ +Q +E++ RE+ ++ ++ K+Q E++ + ++ R
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Query: 502 RQ 503
++
Sbjct: 488 QE 489
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/187 (18%), Positives = 86/187 (45%), Gaps = 15/187 (8%)
Query: 225 KLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQST 284
K+R LE + +K L E+E++ E+K +E +K+ ++ ++Q + T
Sbjct: 435 KIRELEEMMQDQEEK---------LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT 485
Query: 285 QRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQAL 344
R L +Q+ + W + + +++ + E E ++ + K+Q + + + L
Sbjct: 486 WRQEKLLKQEEKIWEQEEKMWRQEEKMW-----EQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 345 RFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQS 404
E + Q+ + +++ L+ + L + S +++L +T + Q++ L ++
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVE-LKSQEA 599
Query: 405 LQLQEQE 411
LQ+Q+
Sbjct: 600 QSLQQQQ 606
Score = 35.8 bits (81), Expect = 0.100
Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 31/211 (14%)
Query: 225 KLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKV--LEEKMNAEQQLQ 282
KLR +E ++ +K + E E++ E+K +E +K E+ + E+++
Sbjct: 449 KLREVEEKMQEEEEK---------MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Query: 283 STQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQ 342
+ + E+K E + + +E + + RE E +L + K+Q + R
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR------ 553
Query: 343 ALRFLENEHQQLQAKIECL------QGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQL 396
L+ LE +L K E L G + L +L T LQ +LK EA+ L QQ
Sbjct: 554 -LQELEERLGKLGQKAELLGGAGRESGSQRLPTL-TPILQVELKSQEAQSL------QQQ 605
Query: 397 QGLLQNQSLQLQEQEKLLTKKDQALPVWSPK 427
Q + Q + L +ALP S +
Sbjct: 606 QDHYRGHLQQYVAAYQQLASGKEALPSCSSR 636
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 70.9 bits (172), Expect = 3e-12
Identities = 102/525 (19%), Positives = 215/525 (40%), Gaps = 68/525 (12%)
Query: 7 RPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRA------ 60
R G RW E + +E +S++C+ ++ T + E ++ A
Sbjct: 76 RKRRGTKRWDEDDDL-----EESEDSKQCKESLKRV-----TFTLPDDEAIEDAGVSHVK 125
Query: 61 ----RLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICR 116
++ F++R ++ EK + + P R G+VT AQ P + +
Sbjct: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVT--------AQKRPENSLLE 177
Query: 117 DLS--DHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKND------ASQQTNYGVA 168
+ DH T I+K K + TI ++ A Q +
Sbjct: 178 ETLHFDHAVRMG-------TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLV 230
Query: 169 VLDKEIIQLS-DYLKEALQRELVL--KQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGK 225
+K IQL+ LK L+R +L +Q++ + D L +Q+ + + Q+ E++L
Sbjct: 231 ESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNL 290
Query: 226 LRSL-------------ENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLE 272
L E + C Q+ ++ + E++ + E+K +E K+
Sbjct: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWR 350
Query: 273 EKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQG 332
++ +Q + + ++ E+ R Q E ++E + Q ++ Q Q K+
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410
Query: 333 ADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTR 392
+ + + ++ +R E E + + KI R+L + QD +++L+ E + +
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKI------RELEEM-MQDQEEKLREVEEKMQEEEEK 463
Query: 393 VQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQK 452
+Q+ + +Q Q ++QEQE+ ++++ L + + E +EK W+ +++Q+
Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLK--QEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 453 KTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
+ ++Q +E++ RE L ++ +LQ E L + Q
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566
Score = 43.9 bits (102), Expect = 4e-04
Identities = 71/362 (19%), Positives = 157/362 (43%), Gaps = 68/362 (18%)
Query: 148 TKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVI---LQDLLST 204
T E T + DA Y + D+E+ + + L+E L+ LV +K I ++DL
Sbjct: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLR--LVESEKSEIQLNVKDLKRK 247
Query: 205 LIQASDSSWKGQLN--EDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQK 262
L +A + QL D+L +L+S+ +L ++ W LL + ++ + Q+
Sbjct: 248 LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWN----LLNQQQEEKMWRQE 303
Query: 263 AKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQ 322
K Q EEKM EQ+L+ + EQ+ + WR E +
Sbjct: 304 EKIQEQ---EEKM-CEQELK-------IREQEEKMWRQ-------------------EEK 333
Query: 323 LHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS 382
+H + K++ + + + + +R E + ++ + K+ Q++ R
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW---------------RQEEKIRE 378
Query: 383 EAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEK 442
+ EK +Q+ + + Q +++EQE+ +K +W + E + + +E+
Sbjct: 379 QDEK------IQEQEEEMWRQEEKIREQEEKRQEK-----MWRQEKKMREQDEKIREQEE 427
Query: 443 D-WDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPR 501
+ W +++++ +Q +E++ RE+ ++ ++ K+Q E++ + ++ R
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Query: 502 RQ 503
++
Sbjct: 488 QE 489
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/187 (18%), Positives = 86/187 (45%), Gaps = 15/187 (8%)
Query: 225 KLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQST 284
K+R LE + +K L E+E++ E+K +E +K+ ++ ++Q + T
Sbjct: 435 KIRELEEMMQDQEEK---------LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT 485
Query: 285 QRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQAL 344
R L +Q+ + W + + +++ + E E ++ + K+Q + + + L
Sbjct: 486 WRQEKLLKQEEKIWEQEEKMWRQEEKMW-----EQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 345 RFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQS 404
E + Q+ + +++ L+ + L + S +++L +T + Q++ L ++
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVE-LKSQEA 599
Query: 405 LQLQEQE 411
LQ+Q+
Sbjct: 600 QSLQQQQ 606
Score = 35.8 bits (81), Expect = 0.100
Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 31/211 (14%)
Query: 225 KLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKV--LEEKMNAEQQLQ 282
KLR +E ++ +K + E E++ E+K +E +K E+ + E+++
Sbjct: 449 KLREVEEKMQEEEEK---------MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Query: 283 STQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQ 342
+ + E+K E + + +E + + RE E +L + K+Q + R
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR------ 553
Query: 343 ALRFLENEHQQLQAKIECL------QGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQL 396
L+ LE +L K E L G + L +L T LQ +LK EA+ L QQ
Sbjct: 554 -LQELEERLGKLGQKAELLGGAGRESGSQRLPTL-TPILQVELKSQEAQSL------QQQ 605
Query: 397 QGLLQNQSLQLQEQEKLLTKKDQALPVWSPK 427
Q + Q + L +ALP S +
Sbjct: 606 QDHYRGHLQQYVAAYQQLASGKEALPSCSSR 636
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 69.3 bits (168), Expect = 8e-12
Identities = 77/319 (24%), Positives = 140/319 (43%), Gaps = 37/319 (11%)
Query: 186 QRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLEN-QLYTCTQKYSPWG 244
+ E ++K K + D+ + + D+S + D+L+ K R +E QL +
Sbjct: 869 REEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASF 928
Query: 245 MKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEA 304
++K +ED EQ +E+ +K EEK E++L ++ + + +C+E +++YE
Sbjct: 929 LQK---SIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYER 985
Query: 305 LKEDWRTLGTQHRE----LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC 360
+ + T+H E L+ L + KL+GA + + Q L L + + +A
Sbjct: 986 ATSETK---TKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAA--- 1039
Query: 361 LQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE----KLLTK 416
+ D + +Q+ + + E L + +Q LQN+ L+E + L K
Sbjct: 1040 ------QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNK 1093
Query: 417 KDQALPVWSPK--SFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNL 474
+ L V + K F E+E L+ +K+ QL A ++E +L EL
Sbjct: 1094 SKELLTVENQKMEEFRKEIE----------TLKQAAAQKSQQLSALQEENVKLAEELGRS 1143
Query: 475 SDEYLSCLRKLQHCREELN 493
DE S +KL+ R LN
Sbjct: 1144 RDEVTS-HQKLEEERSVLN 1161
Score = 48.5 bits (114), Expect = 1e-05
Identities = 62/277 (22%), Positives = 115/277 (41%), Gaps = 53/277 (19%)
Query: 245 MKKVLLEMEDQKNSYEQKA---KESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQ 301
+++ L E+ K + E++ KE + EE ++ ++ +Q T L E++ S
Sbjct: 789 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSD 848
Query: 302 YEALKEDWRTLGTQHREL---ESQLHVLQSKLQ----------GADSRDL-QMNQALRFL 347
E L+E+ + + RE E QL + KL+ G +S L +MN LR
Sbjct: 849 LEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLK 908
Query: 348 ENEHQQLQAKIECLQGDRDLCSLDTQDL--------QDQLKRSEAEKLTLVTRVQQLQGL 399
E + ++LQ K+ + +D+ Q+ K+ E EK L ++ L+
Sbjct: 909 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 968
Query: 400 LQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
++ Q QE L + ++A K K ++ LQK L +
Sbjct: 969 METSHNQCQE---LKARYERA---------------TSETKTKHEEILQNLQKTLLDTED 1010
Query: 460 KEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQ 496
K K RE +S L L++L+ R++ ++++
Sbjct: 1011 KLKGAREENSGL----------LQELEELRKQADKAK 1037
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/254 (22%), Positives = 120/254 (47%), Gaps = 13/254 (5%)
Query: 252 MEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRT 311
ME+ K S+ + + E K E+ Q + + + + R+ + E R
Sbjct: 592 MEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA 651
Query: 312 -LGTQHRELESQLHVLQSKLQGADSRDL-QMNQALRFLENEHQQLQAKIECLQGDRDLCS 369
L +E E+ L ++SKL A+ + L +M L N+ Q+ + K++ L+ + C+
Sbjct: 652 KLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL----NKLQEAEIKVKELEVLQAKCN 707
Query: 370 LDTQDLQD---QLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVW-- 424
T+ + + QLK +E EKL + +++ +++ +L++Q + K+ + L +
Sbjct: 708 EQTKVIDNFTSQLKATE-EKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKN 766
Query: 425 SPKSFPNEVEPEGTGKE-KDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLR 483
+ S + + E G+E K +L++ L + + + EKE + L + S+E +S R
Sbjct: 767 AESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQR 826
Query: 484 KLQHCREELNQSQQ 497
+Q +L+Q ++
Sbjct: 827 SMQETVNKLHQKEE 840
Score = 44.7 bits (104), Expect = 2e-04
Identities = 69/305 (22%), Positives = 131/305 (42%), Gaps = 39/305 (12%)
Query: 221 KLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQ---KAKESLQKVLEEKMNA 277
KL ++ EN L K + L+EMED N ++ K KE +VL+ K N
Sbjct: 652 KLMKVIKEKENSLEAIRSKLDK-AEDQHLVEMEDTLNKLQEAEIKVKEL--EVLQAKCNE 708
Query: 278 E--------QQLQSTQRSL--------ALAEQKCE--EWRSQYEALKEDWRTLGTQHREL 319
+ QL++T+ L A +E K E + R Q EA ++ + L +
Sbjct: 709 QTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAE 768
Query: 320 ESQLHVLQSKLQGADSR--DLQMN-----QALRFLENEHQQLQAKIECLQGDRDLCSLDT 372
S+ + +LQG + + +LQ N Q LE E Q L+ K +
Sbjct: 769 SSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSM 828
Query: 373 QDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNE 432
Q+ ++L + E + L + +++L+ L + + +E+++ +++Q + + + N+
Sbjct: 829 QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDE---REEQLIK--AKEKLEND 883
Query: 433 VEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREEL 492
+ + D QL K +L+ KE++ EL +L ++ + ++ +
Sbjct: 884 IAEI---MKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKA 940
Query: 493 NQSQQ 497
QSQQ
Sbjct: 941 EQSQQ 945
Score = 39.7 bits (91), Expect = 0.007
Identities = 60/270 (22%), Positives = 120/270 (44%), Gaps = 28/270 (10%)
Query: 233 LYTCTQKYSPWGMK-KVLLEMEDQKNSYEQKA-KESLQKVLEEKMNAEQQLQ-STQRSLA 289
LYT T+K S K LE +++NS K L+ + A ++L+ S + L
Sbjct: 545 LYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLG 604
Query: 290 LAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQA--LRFL 347
+ E ++Q E ++ D+ QH E+E+ L Q + A +++++ +A ++ +
Sbjct: 605 TETAEFAELKTQIEKMRLDY-----QH-EIEN-LQNQQDSERAAHAKEMEALRAKLMKVI 657
Query: 348 ENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQL 407
+ + L+A L D ++ +D ++L+ +E +V++L+ L +
Sbjct: 658 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI-------KVKELEVL----QAKC 706
Query: 408 QEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECREL 467
EQ K++ L K + + + + K +++K QL+A EK+ + L
Sbjct: 707 NEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKS-----EMKKLRQQLEAAEKQIKHL 761
Query: 468 HSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E + S + S R+LQ +L Q+
Sbjct: 762 EIEKNAESSKASSITRELQGRELKLTNLQE 791
Score = 38.5 bits (88), Expect = 0.015
Identities = 56/231 (24%), Positives = 103/231 (44%), Gaps = 18/231 (7%)
Query: 266 SLQKVLEEKMNAEQQLQSTQRSLALAE-QKCEEWRSQYEALKEDWRTLGTQH-RELESQL 323
+LQ+ L+EK +QL + +R L AE K + E R QH ELE+++
Sbjct: 352 ALQEALKEKQQHIEQLLA-ERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKM 410
Query: 324 HVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE---CLQGDRDLCSLDTQDLQDQLK 380
L++ ++ AD +++ L + + + LQ ++E +GD L+ + ++ +
Sbjct: 411 DQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGD-----LEVATVSEKSR 465
Query: 381 RSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGK 440
E EK L RVQ++ L + E K D +L + S E + E T
Sbjct: 466 IMELEK-DLALRVQEVAELRRRL-----ESNKPAGDVDMSLSLLQEISSLQE-KLEVTRT 518
Query: 441 EKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREE 491
+ ++ + + + +KE + L++ + LS E S KL+H +E
Sbjct: 519 DHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKE 569
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 69.3 bits (168), Expect = 8e-12
Identities = 77/319 (24%), Positives = 140/319 (43%), Gaps = 37/319 (11%)
Query: 186 QRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLEN-QLYTCTQKYSPWG 244
+ E ++K K + D+ + + D+S + D+L+ K R +E QL +
Sbjct: 904 REEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASF 963
Query: 245 MKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEA 304
++K +ED EQ +E+ +K EEK E++L ++ + + +C+E +++YE
Sbjct: 964 LQK---SIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYER 1020
Query: 305 LKEDWRTLGTQHRE----LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC 360
+ + T+H E L+ L + KL+GA + + Q L L + + +A
Sbjct: 1021 ATSETK---TKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAA--- 1074
Query: 361 LQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE----KLLTK 416
+ D + +Q+ + + E L + +Q LQN+ L+E + L K
Sbjct: 1075 ------QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNK 1128
Query: 417 KDQALPVWSPK--SFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNL 474
+ L V + K F E+E L+ +K+ QL A ++E +L EL
Sbjct: 1129 SKELLTVENQKMEEFRKEIE----------TLKQAAAQKSQQLSALQEENVKLAEELGRS 1178
Query: 475 SDEYLSCLRKLQHCREELN 493
DE S +KL+ R LN
Sbjct: 1179 RDEVTS-HQKLEEERSVLN 1196
Score = 48.5 bits (114), Expect = 1e-05
Identities = 62/277 (22%), Positives = 115/277 (41%), Gaps = 53/277 (19%)
Query: 245 MKKVLLEMEDQKNSYEQKA---KESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQ 301
+++ L E+ K + E++ KE + EE ++ ++ +Q T L E++ S
Sbjct: 824 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSD 883
Query: 302 YEALKEDWRTLGTQHREL---ESQLHVLQSKLQ----------GADSRDL-QMNQALRFL 347
E L+E+ + + RE E QL + KL+ G +S L +MN LR
Sbjct: 884 LEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLK 943
Query: 348 ENEHQQLQAKIECLQGDRDLCSLDTQDL--------QDQLKRSEAEKLTLVTRVQQLQGL 399
E + ++LQ K+ + +D+ Q+ K+ E EK L ++ L+
Sbjct: 944 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1003
Query: 400 LQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
++ Q QE L + ++A K K ++ LQK L +
Sbjct: 1004 METSHNQCQE---LKARYERA---------------TSETKTKHEEILQNLQKTLLDTED 1045
Query: 460 KEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQ 496
K K RE +S L L++L+ R++ ++++
Sbjct: 1046 KLKGAREENSGL----------LQELEELRKQADKAK 1072
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/254 (22%), Positives = 120/254 (47%), Gaps = 13/254 (5%)
Query: 252 MEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRT 311
ME+ K S+ + + E K E+ Q + + + + R+ + E R
Sbjct: 627 MEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA 686
Query: 312 -LGTQHRELESQLHVLQSKLQGADSRDL-QMNQALRFLENEHQQLQAKIECLQGDRDLCS 369
L +E E+ L ++SKL A+ + L +M L N+ Q+ + K++ L+ + C+
Sbjct: 687 KLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL----NKLQEAEIKVKELEVLQAKCN 742
Query: 370 LDTQDLQD---QLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVW-- 424
T+ + + QLK +E EKL + +++ +++ +L++Q + K+ + L +
Sbjct: 743 EQTKVIDNFTSQLKATE-EKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKN 801
Query: 425 SPKSFPNEVEPEGTGKE-KDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLR 483
+ S + + E G+E K +L++ L + + + EKE + L + S+E +S R
Sbjct: 802 AESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQR 861
Query: 484 KLQHCREELNQSQQ 497
+Q +L+Q ++
Sbjct: 862 SMQETVNKLHQKEE 875
Score = 44.7 bits (104), Expect = 2e-04
Identities = 69/305 (22%), Positives = 131/305 (42%), Gaps = 39/305 (12%)
Query: 221 KLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQ---KAKESLQKVLEEKMNA 277
KL ++ EN L K + L+EMED N ++ K KE +VL+ K N
Sbjct: 687 KLMKVIKEKENSLEAIRSKLDK-AEDQHLVEMEDTLNKLQEAEIKVKEL--EVLQAKCNE 743
Query: 278 E--------QQLQSTQRSL--------ALAEQKCE--EWRSQYEALKEDWRTLGTQHREL 319
+ QL++T+ L A +E K E + R Q EA ++ + L +
Sbjct: 744 QTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAE 803
Query: 320 ESQLHVLQSKLQGADSR--DLQMN-----QALRFLENEHQQLQAKIECLQGDRDLCSLDT 372
S+ + +LQG + + +LQ N Q LE E Q L+ K +
Sbjct: 804 SSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSM 863
Query: 373 QDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNE 432
Q+ ++L + E + L + +++L+ L + + +E+++ +++Q + + + N+
Sbjct: 864 QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDE---REEQLIK--AKEKLEND 918
Query: 433 VEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREEL 492
+ + D QL K +L+ KE++ EL +L ++ + ++ +
Sbjct: 919 IAEI---MKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKA 975
Query: 493 NQSQQ 497
QSQQ
Sbjct: 976 EQSQQ 980
Score = 39.7 bits (91), Expect = 0.007
Identities = 61/259 (23%), Positives = 111/259 (42%), Gaps = 39/259 (15%)
Query: 266 SLQKVLEEKMNAEQQLQSTQRSLALAE-QKCEEWRSQYEALKEDWRTLGTQH-RELESQL 323
+LQ+ L+EK +QL + +R L AE K + E R QH ELE+++
Sbjct: 352 ALQEALKEKQQHIEQLLA-ERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKM 410
Query: 324 HVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE---CLQGDRDLCSLDTQDLQDQLK 380
L++ ++ AD +++ L + + + LQ ++E +GD L+TQ + +
Sbjct: 411 DQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGD-----LETQTKLEHAR 465
Query: 381 RSEAEKLTLV--TRVQQLQGLLQNQSLQ-LQEQEKLLT-KKDQALPVWSPKSFPNEVEPE 436
E E+ L T+ +LQ L++ + + E+ +++ +KD AL V +E
Sbjct: 466 IKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESN 525
Query: 437 GTGKEKDWDL----------------RDQLQKKTLQL--------QAKEKECRELHSELD 472
+ D L R Q++ L + +KE + L++ +
Sbjct: 526 KPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATE 585
Query: 473 NLSDEYLSCLRKLQHCREE 491
LS E S KL+H +E
Sbjct: 586 KLSKENESLKSKLEHANKE 604
Score = 39.7 bits (91), Expect = 0.007
Identities = 60/270 (22%), Positives = 120/270 (44%), Gaps = 28/270 (10%)
Query: 233 LYTCTQKYSPWGMK-KVLLEMEDQKNSYEQKA-KESLQKVLEEKMNAEQQLQ-STQRSLA 289
LYT T+K S K LE +++NS K L+ + A ++L+ S + L
Sbjct: 580 LYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLG 639
Query: 290 LAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQA--LRFL 347
+ E ++Q E ++ D+ QH E+E+ L Q + A +++++ +A ++ +
Sbjct: 640 TETAEFAELKTQIEKMRLDY-----QH-EIEN-LQNQQDSERAAHAKEMEALRAKLMKVI 692
Query: 348 ENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQL 407
+ + L+A L D ++ +D ++L+ +E +V++L+ L +
Sbjct: 693 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI-------KVKELEVL----QAKC 741
Query: 408 QEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECREL 467
EQ K++ L K + + + + K +++K QL+A EK+ + L
Sbjct: 742 NEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKS-----EMKKLRQQLEAAEKQIKHL 796
Query: 468 HSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E + S + S R+LQ +L Q+
Sbjct: 797 EIEKNAESSKASSITRELQGRELKLTNLQE 826
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 68.9 bits (167), Expect = 1e-11
Identities = 116/520 (22%), Positives = 216/520 (41%), Gaps = 70/520 (13%)
Query: 13 ARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLE 72
AR E+ EA + + + R V G+ R +RE R R Q ++
Sbjct: 791 ARLREAVEAAGQELESASQEREAL--VEALAAAGRERRQWEREG-SRLRAQSEAAEERMQ 847
Query: 73 LEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPPQ 132
+ E QH + E+ RR + E + L L A L Q
Sbjct: 848 VLESEGRQHLEEAER--ERREKEALQAELEKAVVRGKELGARLEHLQRELEQAA--LERQ 903
Query: 133 DTPIKKPPKHHR--GTQTKAEGP-----TIKNDASQQTNYGVAVLDKEIIQLSDYL---- 181
+ +K +H R G + + E T K +A + L++E+ QL
Sbjct: 904 EFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLG 963
Query: 182 -KEALQRELVLKQKMVILQ-DLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQK 239
K+ + +LV Q + +++ + + ++ A ++ +GQL L+G+L SL+ +
Sbjct: 964 PKKRAEPQLVETQNVRLIEVERSNAMLVAEKAALQGQLQH--LEGQLGSLQGR------- 1014
Query: 240 YSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
+ +L Q++S +A++S+ ++ ++++ ++L+ + + A Q EE R
Sbjct: 1015 ----AQELLLQSQRAQEHSSRLQAEKSVLEIQGQELH--RKLEVLEEEVRAARQSQEETR 1068
Query: 300 SQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
Q +AL D + L R E++L L + RDL+ N +R LE H++LQ + E
Sbjct: 1069 GQQQALLRDHKALAQLQRRQEAELEGLLVR-----HRDLKAN--MRALELAHRELQGRHE 1121
Query: 360 CLQGDRDLCSLDTQD-------------------LQDQLKRSEAEKLTLVTRVQQLQGLL 400
LQ R S++ Q+ L+++L+R ++E R Q L L
Sbjct: 1122 QLQAQR--ASVEAQEVALLAERERLMQDGHRQRGLEEELRRLQSEH----DRAQMLLAEL 1175
Query: 401 QNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWD---LRDQLQKKTLQL 457
+ +LQ + L + L + + + + ++ D L Q + T
Sbjct: 1176 SRERGELQGERGELRGRLARLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLR 1235
Query: 458 QAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
A+E+E R+L +E+ LS E L + R+ L++ Q+
Sbjct: 1236 SAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQR 1275
Score = 43.9 bits (102), Expect = 4e-04
Identities = 55/245 (22%), Positives = 113/245 (46%), Gaps = 34/245 (13%)
Query: 214 KGQLNEDKLKGKLRSLENQ---LYTCTQKYSPWGMKKVLLEMEDQKNSYEQ-KAKESLQK 269
K + D+L+ + R LE Q +++ + + E + ++EQ + +E+++
Sbjct: 740 KAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREAEAQAWEQARLREAVEA 799
Query: 270 VLEEKMNAEQQLQSTQRSLALAEQKCEEW-------RSQYEALKEDWRTLGTQHRELESQ 322
+E +A Q+ ++ +LA A ++ +W R+Q EA +E + L E E +
Sbjct: 800 AGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERMQVL-----ESEGR 854
Query: 323 LHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS 382
H+ +++ + + LQ + ++L A++E LQ + + +L+ Q+ L+
Sbjct: 855 QHLEEAERERREKEALQAELEKAVVRG--KELGARLEHLQRELEQAALERQEF---LREK 909
Query: 383 EAEKLTLVTRVQQLQGLLQNQSLQLQ-----EQEKLLTKKDQALPVWSPKSFPNEVEPEG 437
E++ Q+ QGL Q +LQ ++E L+ K +AL + + F P G
Sbjct: 910 ESQH-------QRYQGLEQRLEAELQAAATSKEEALMELKTRALQL-EEELFQLRQGPAG 961
Query: 438 TGKEK 442
G +K
Sbjct: 962 LGPKK 966
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/155 (24%), Positives = 70/155 (45%), Gaps = 16/155 (10%)
Query: 224 GKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQS 283
G+L L+ +L C ++ K LE E + + +K L++ LE +L
Sbjct: 327 GRLPRLQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKALLEEQLEAARERCARLHE 386
Query: 284 TQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVL---------QSKLQGA- 333
TQR L + E ++ ++L+ L ++ ELE +L ++ L GA
Sbjct: 387 TQRENLLLRTRLGEAHAELDSLRHQVDQLAEENVELELELQRSLEPPPGSPGEAPLAGAA 446
Query: 334 -----DSRDLQMNQALRFLENEHQQLQAKIECLQG 363
+ R+ + + LR LE E+++L+ ++ LQG
Sbjct: 447 PSLQDEVREAEAGR-LRTLERENRELRGLLQVLQG 480
Score = 30.0 bits (66), Expect = 5.5
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 16/192 (8%)
Query: 312 LGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLD 371
L Q ++QL L+ +L+ L ++ LE E ++L+ + + L G
Sbjct: 256 LALQLANAKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSG-------- 307
Query: 372 TQDLQDQLKRSEAEKLT-LVTRVQQLQGLLQN--QSLQLQEQEKLLTKKDQALPVWSPKS 428
Q + +L R EAE L R+ +LQ L+ + LQ E K ++++ L S
Sbjct: 308 -QAKRAELYREEAEALRERAGRLPRLQEELRRCRERLQAAEAYKSQLEEERVLSGVLEAS 366
Query: 429 FPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHC 488
E +E+ L + Q++ L L+ + E H+ELD+L + +
Sbjct: 367 KALLEEQLEAARERCARLHET-QRENLLLRTR---LGEAHAELDSLRHQVDQLAEENVEL 422
Query: 489 REELNQSQQLPP 500
EL +S + PP
Sbjct: 423 ELELQRSLEPPP 434
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 67.0 bits (162), Expect = 4e-11
Identities = 121/511 (23%), Positives = 208/511 (40%), Gaps = 88/511 (17%)
Query: 48 TLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQ 107
TL Q+ + LQ + ++ + L+ +E K Q Q +E P G VT +S+E+ +
Sbjct: 86 TLLRQEVQDLQASLKEEKWYSEELK-KELEKYQGLQQQEAKPD---GLVTDSSAELQSLE 141
Query: 108 HPPPSGIC-----RDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQ 162
+ + D +A L + IK R + AE Q+
Sbjct: 142 QQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAE---------QK 192
Query: 163 TNYGVAVLDKEIIQLSDYLKEALQRE-----LVLKQKMVILQDLLSTLI----------- 206
L+KE + D E LQR VLK+++V +Q L+ +
Sbjct: 193 VTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLK 252
Query: 207 ---------QASDSSWKGQLNEDKLKG---------KLRSLENQLYTCTQKYSPWGMKKV 248
AS + QL + KG +L+ L++ + TQK + +
Sbjct: 253 DECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQT--LTEN 310
Query: 249 LLEME------DQKNSYEQKAKESLQKVLEEKMNAEQQLQS----TQRSLALAEQKCEEW 298
LL+ E ++K++ E +K+++Q L +K QQLQS ++ SL + E
Sbjct: 311 LLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEK 370
Query: 299 RSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQAL-----RFLENEHQQ 353
+ LKE+ + T+++ L+++ LQ + + + LQ+ + + LE E Q
Sbjct: 371 GEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQL 430
Query: 354 LQAKIECLQGDRDLCS---LDTQ----DLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQ 406
+A L+ R L S +D + DLQ +L R E + VT +LQ L Q
Sbjct: 431 GEAHGR-LKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQ 489
Query: 407 LQEQEKLLTKKDQALPVWSPKSFPNEVEPE----GTGKEKDWDLRDQLQKKTLQLQAKEK 462
QEQ+ L L + N++E G +K +L LQK + EK
Sbjct: 490 HQEQQALQQSTTAKL-----REAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEK 544
Query: 463 ECRELHSELDNLSDE--YLSCLRKLQHCREE 491
E +L++++ E L+ L++ H +E
Sbjct: 545 EREDLYAKIQAGEGETAVLNQLQEKNHTLQE 575
Score = 58.5 bits (140), Expect = 1e-08
Identities = 60/253 (23%), Positives = 110/253 (43%), Gaps = 28/253 (11%)
Query: 249 LLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKED 308
LLE E Q + KE Q E+ M+ EQQ+ Q L+ E++ +E + L+
Sbjct: 423 LLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQ 482
Query: 309 WRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLC 368
QH+E ++ +KL+ A + + Q LR + ++ Q++Q LQ ++
Sbjct: 483 LDKTKQQHQEQQALQQSTTAKLREAQN---DLEQVLRQIGDKDQKIQNLEALLQKSKENI 539
Query: 369 SL---DTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWS 425
SL + +DL +++ E E L LQ ++ LQEQ LT+K
Sbjct: 540 SLLEKEREDLYAKIQAGEGETAVL--------NQLQEKNHTLQEQVTQLTEK-------- 583
Query: 426 PKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKL 485
N+ E + K+ +L DQ+Q++ L+A + L + ++ L+ + K+
Sbjct: 584 ---LKNQSE---SHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKV 637
Query: 486 QHCREELNQSQQL 498
++ +L
Sbjct: 638 SQLDIQIKAKTEL 650
Score = 57.4 bits (137), Expect = 3e-08
Identities = 82/361 (22%), Positives = 158/361 (43%), Gaps = 50/361 (13%)
Query: 151 EGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQ---------RELVLKQKMVI--LQ 199
EG T + Q+ N+ L +++ QL++ LK + + V +QK + Q
Sbjct: 557 EGETAVLNQLQEKNH---TLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQ 613
Query: 200 DLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSY 259
D + +L + S + QLNE K K+ L+ Q+ T+ K + Q ++
Sbjct: 614 DRVLSL-ETSVNELNSQLNESK--EKVSQLDIQIKAKTELLLSAEAAKTAQRADLQ--NH 668
Query: 260 EQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHREL 319
A+ +LQ +E QL L ++ C + S + KE + +L + EL
Sbjct: 669 LDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEEL 728
Query: 320 ESQLHVLQSKLQGADSRDLQMN--QALRFLENEHQQLQAKIECLQGDRDLCSLD-TQDLQ 376
E Q+ L+ ADS +++ + QAL+ L+ + Q L D +L + + ++ L+
Sbjct: 729 EGQIKKLE-----ADSLEVKASKEQALQDLQQQRQ--------LNTDLELRATELSKQLE 775
Query: 377 DQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPE 436
+ + + +L L + + L+ + Q L QE+EK + K+D + S +++ E
Sbjct: 776 MEKEIVSSTRLDLQKKSEALESI--KQKLTKQEEEKQILKQD-----FETLSQETKIQHE 828
Query: 437 GTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQ 496
+L +++Q +LQ + E L +EL + D+ L++ + E +
Sbjct: 829 --------ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKEN 880
Query: 497 Q 497
Q
Sbjct: 881 Q 881
Score = 52.4 bits (124), Expect = 1e-06
Identities = 57/237 (24%), Positives = 109/237 (45%), Gaps = 18/237 (7%)
Query: 182 KEALQREL-VLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKY 240
K+ L+++ L Q+ I + L+ IQ + + + K+K + +L +L T K
Sbjct: 809 KQILKQDFETLSQETKIQHEELNNRIQTTVTELQ------KVKMEKEALMTELSTVKDKL 862
Query: 241 SPWGMKKVLLEMEDQKNSYE---QKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEE 297
S KV +++ K+ +E QK K ++ + + + QLQ Q L EQK E
Sbjct: 863 S-----KVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ-VQMENTLKEQK--E 914
Query: 298 WRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAK 357
+ E KE L + ++ QL Q+ L+ + + Q+ + L+ +Q + +
Sbjct: 915 LKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQ 974
Query: 358 IECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLL 414
IE LQG+ + L +L+++L++ + + ++ +LQN + QE K L
Sbjct: 975 IEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQL 1031
Score = 51.6 bits (122), Expect = 2e-06
Identities = 77/355 (21%), Positives = 159/355 (44%), Gaps = 48/355 (13%)
Query: 175 IQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLR------- 227
++L+ ++ +Q + LKQ Q L + + SS + + + L+G+L+
Sbjct: 931 LELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKT 990
Query: 228 SLENQL-YTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVL-------EEKMNAEQ 279
LEN+L TQ +K + + +N+YE K++E+ +++ E + Q
Sbjct: 991 ELENKLQQQLTQAAQELAAEKEKISV--LQNNYE-KSQETFKQLQSDFYGRESELLATRQ 1047
Query: 280 QLQSTQRSLALAEQKCEEWRSQ-------YEALKEDWRTLGTQHRELESQLHVLQSKLQG 332
L+S + L+LA++ R+Q + LK TL + E QL LQ
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQ- 1106
Query: 333 ADSRDLQMNQALRFLE--NEHQQLQ--AKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLT 388
D+Q ++L+ E NE +L +I+C Q + L ++LK + E +
Sbjct: 1107 ----DIQKEKSLKEKELVNEKSKLAEIEEIKCRQ------EKEITKLNEELKSHKLESIK 1156
Query: 389 LVTRVQQLQGLLQNQSLQLQEQEKLL------TKKDQALPVWSPKSFPNEVEPEGTGKEK 442
+T ++ + LL Q L+LQ + L K++Q + K E++ E EK
Sbjct: 1157 EITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFI--EK 1214
Query: 443 DWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
+ L ++++K + ++ E+ +L ++ L++ + ++ Q + +++ ++
Sbjct: 1215 EAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEK 1269
Score = 39.3 bits (90), Expect = 0.009
Identities = 65/283 (22%), Positives = 131/283 (46%), Gaps = 27/283 (9%)
Query: 156 KNDASQQTNYGVAVLDKEIIQLSDYLKEA------LQRELVLKQKMVILQDLLSTLIQAS 209
+N Q+ A L+++ + L+E +Q+E LK+K ++ + S L +
Sbjct: 1073 QNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK--SKLAEIE 1130
Query: 210 DSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQK 269
+ + + KL +L+S ++L + + + K++L++ QK + KA +SL+
Sbjct: 1131 EIKCRQEKEITKLNEELKS--HKLESIKEITNLKDAKQLLIQ---QKLELQGKA-DSLKA 1184
Query: 270 VLEEKMNAEQQL--QSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQ-HRELESQLHVL 326
+E++ +Q L Q + L ++ E+ + +KE + +G + H E E++L +
Sbjct: 1185 AVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKE--KEVGMKKHEENEAKLTMQ 1242
Query: 327 QSKLQ---GADSRDLQMNQA-LRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS 382
+ L G ++ Q +Q + LE + L+ +I L+ + + L ++ +
Sbjct: 1243 ITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKG 1302
Query: 383 EAEKLTLVTRVQQLQGLLQNQSLQLQ----EQEKLLTKKDQAL 421
E E L T+V +LQ L N + +Q E + L K QAL
Sbjct: 1303 EGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQAL 1345
Score = 38.1 bits (87), Expect = 0.020
Identities = 57/234 (24%), Positives = 97/234 (41%), Gaps = 33/234 (14%)
Query: 279 QQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELE---------SQLHVLQSK 329
Q++Q Q SL K E+W S+ E KE + G Q +E + ++L L+ +
Sbjct: 90 QEVQDLQASL-----KEEKWYSE-ELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQ 143
Query: 330 LQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTL 389
L+ A + + + Q E + QL +I ++ D + + ++ R E
Sbjct: 144 LEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKE 203
Query: 390 VTRVQQLQG-LLQNQSLQLQEQEKLLTKKD--QALPVWSPKSFPNEVEPEGTGKEKDWDL 446
T +Q L+ LLQ ++ + + KK+ Q + + E E E L
Sbjct: 204 ATVIQDLKTELLQRPGIE----DVAVLKKELVQVQTLMDNMTLERERESE--------KL 251
Query: 447 RDQLQKKTLQLQAKEKECRELHSELDNLSDE---YLSCLRKLQHCREELNQSQQ 497
+D+ +K Q + E +L SEL E Y+ L+KL+ EL Q Q
Sbjct: 252 KDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQ 305
Score = 31.2 bits (69), Expect = 2.5
Identities = 30/140 (21%), Positives = 61/140 (43%), Gaps = 12/140 (8%)
Query: 355 QAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLL 414
++ + + D L + QDLQ LK + L +++ QGL Q ++ + + L+
Sbjct: 75 ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEA----KPDGLV 130
Query: 415 TKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNL 474
T L +S ++E T ++D ++K QL + + + + E +L
Sbjct: 131 TDSSAEL-----QSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSL 185
Query: 475 SDEYLSCLRKLQHCREELNQ 494
+ + +K+ EELN+
Sbjct: 186 RE---AAEQKVTRLTEELNK 202
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 66.6 bits (161), Expect = 5e-11
Identities = 94/392 (23%), Positives = 165/392 (42%), Gaps = 50/392 (12%)
Query: 117 DLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQ 176
DL Q GL + + K H+ K +N+ VA L+K++ +
Sbjct: 546 DLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENM------VAKLNKKVKE 599
Query: 177 LSD---YLKEALQ-RELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQ 232
L + +LK+ L +E V KQ ++ L S + + + Q++ D+L+ K RS++
Sbjct: 600 LEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAA 659
Query: 233 LYTCTQKYSPWGMKKVLLEMEDQKN--SYEQKAKESLQKVLEEKMNAEQQLQSTQR---- 286
L + ++ + + E Q+ S E KAKE L LE+ +Q Q T
Sbjct: 660 LDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVG 719
Query: 287 SLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRF 346
L LA Q+ E Q A KED+ L ++ LQ +LQ A++R+ +++Q++
Sbjct: 720 DLRLALQRTE----QAAARKEDY---------LRHEIGELQQRLQEAENRNQELSQSV-- 764
Query: 347 LENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQ 406
+ + L +IE LQ + + L+ L E TL+ + +
Sbjct: 765 -SSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAAT----- 818
Query: 407 LQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRE 466
E+LL K Q + S S ++++ + QL+ + +L E E
Sbjct: 819 ----EELLANKIQMSSMESQNSLL---------RQENSRFQAQLESEKNRLCKLEDENNR 865
Query: 467 LHSELDNLSDEYLSCLRKLQHCREELNQSQQL 498
EL+NL DEY+ L + + + LN ++
Sbjct: 866 YQVELENLKDEYVRTLEETRKEKTLLNSQLEM 897
Score = 36.6 bits (83), Expect = 0.059
Identities = 50/234 (21%), Positives = 107/234 (45%), Gaps = 18/234 (7%)
Query: 262 KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELES 321
K E L + LE++ E QL S + AL E+ + + + +KE+ ++ + E
Sbjct: 449 KTVEFLNEKLEKR---EAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQ 505
Query: 322 QLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKR 381
++ + K+Q A + + A + ++N ++L ++ + DL L +D Q +
Sbjct: 506 RIAEAEKKVQLACK---ERDAAKKEIKNIKEELATRLNSSE-TADL--LKEKDEQIRGLM 559
Query: 382 SEAEKLTLVTRVQQL--QGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTG 439
E EKL+ QQL +++ + +E E ++ K ++ + + ++ G
Sbjct: 560 EEGEKLS----KQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEEL--QHLKQVLDG 613
Query: 440 KEK-DWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREEL 492
KE+ + R+ ++K ++ +EK+ L ++D L ++ S L +EL
Sbjct: 614 KEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKEL 667
Score = 30.0 bits (66), Expect = 5.5
Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 191 LKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWG--MKKV 248
L++ I+ + L L +D + KL+ +LR L+ + T Q Y +++
Sbjct: 1010 LEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEEL 1069
Query: 249 LLEMEDQKNSYEQKAKESLQKVL 271
L++ED KN Y+ + E L++ L
Sbjct: 1070 RLDLEDVKNMYKTQIDELLRQSL 1092
Score = 29.6 bits (65), Expect = 7.2
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 430 PNEVEPEGTGKEKDWD-----LRDQLQKKTLQLQAKEKECRELHSELDNLSDE 477
P E +PE +++D L ++L+K+ QL + KE L DNL DE
Sbjct: 433 PAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDE 485
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 65.9 bits (159), Expect = 9e-11
Identities = 94/504 (18%), Positives = 214/504 (42%), Gaps = 54/504 (10%)
Query: 20 EAKCERRQEI--RESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLELEEKG 77
E K ++E R+ +R R R+ K LR Q+ + Q ++Q E EEK
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQ--------EQEEKM 357
Query: 78 KAQHPQAREQGPS--RRPGQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPPQDTP 135
Q + REQ R+ ++ ++ + RD + + Q L ++
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK-----MRDQEERMWEQDERLREKEER 412
Query: 136 IKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKM 195
+++ K + E ++ + + + ++E I+ + K+ + E ++++
Sbjct: 413 MREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE--KKMREEEETMREQE 470
Query: 196 VILQDLLSTLIQASDSSWKGQ-LNEDKLK----GKLRSLENQLYTCTQKYSP----WGMK 246
+Q + + + W+ Q L E K K K++ E +++ +K WG +
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 247 KVLL------EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRS 300
K + E EDQ E+K ++ QK+ +++ E++ Q ++ E+K E
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE--- 587
Query: 301 QYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC 360
+E R + RE E + + K+Q + + Q + E E + + + +
Sbjct: 588 -----EERMREREKKMREEEEMMREQEEKMQ--EQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 361 LQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTK-KDQ 419
+ + + + + + Q + EKL ++Q+ Q +Q Q ++ EQEK+ K ++Q
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-QEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 420 ALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYL 479
W + ++ E + +E++ +R++ + ++ +E++ +E ++ +E
Sbjct: 700 EKKTWDQE----KMREEESMREREKKMREEEE----MMREQEEKMQEQEEKMQEQEEEMW 751
Query: 480 SCLRKLQHCREELNQSQQLPPRRQ 503
K+ E++ + Q+LP +++
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKE 775
Score = 63.5 bits (153), Expect = 4e-10
Identities = 68/330 (20%), Positives = 164/330 (49%), Gaps = 27/330 (8%)
Query: 143 HRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLL 202
+R T T E K +A Q +A +K IQL+ +KE L+R+L + K ++ Q
Sbjct: 214 YRNTITNEE--LKKKNAELQEKLPLAESEKSEIQLN--VKE-LKRKLE-RAKFLLPQVQT 267
Query: 203 STLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQK 262
+TL + W+ + + + K+R E +++ ++ K + E E++ E++
Sbjct: 268 NTL---QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK--MREQEEKMWRQEKR 322
Query: 263 AKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHREL--- 319
+E +++ E++ +Q + ++ + EQ+ + W Q E ++E + Q L
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWE-QEEKMREQEEKMWRQEERLWEQ 381
Query: 320 ESQLHVLQSKLQGADSRDLQMNQALRFLEN---EHQQLQAKIECLQGDRDLCSLDTQDLQ 376
E Q+ + K++ + R + ++ LR E E +++ ++E ++ ++ + Q
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE------Q 435
Query: 377 DQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPE 436
++ R + EK+ R+++ + ++ + ++EQE+ + K+++ + K + + PE
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 437 GTGKEKDWDLRDQLQKKTLQLQAKEKECRE 466
KEK W+ ++++Q++ ++ +E++ R+
Sbjct: 496 --QKEKLWE-QEKMQEQEEKIWEQEEKIRD 522
Score = 38.5 bits (88), Expect = 0.015
Identities = 42/273 (15%), Positives = 124/273 (45%), Gaps = 21/273 (7%)
Query: 238 QKYSPWGMKKVLLEMED-----QKNSYEQKAKESLQKVL---EEKMNAEQQLQSTQRSLA 289
Q+ W ++ + E E+ ++ +EQ+ K Q+ L +EK+ +++Q ++
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 290 LAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLEN 349
E+ E+ + + + +++ +T + E + + K++ + ++ Q + E
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR--EEEEMMREQEEKMQEQ 739
Query: 350 EHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGL------LQNQ 403
E + + + E + + + + + + Q + EKL ++Q+ + + +++Q
Sbjct: 740 EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 404 SLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQL----QKKTLQLQA 459
+++ QE+ + +++ + K + E + G +EK W +++ +K ++Q
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQ-EEKMWGQEEKMWGQEEKMEEKMQG 858
Query: 460 KEKECRELHSELDNLSDEYLSCLRKLQHCREEL 492
+E++ RE ++ ++ K++ E++
Sbjct: 859 QEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 33.5 bits (75), Expect = 0.50
Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 210 DSSWKGQLNEDKLKG---KLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKES 266
D K + E+K++G K+R E +++ +K WG ++ + E++ E+K +E
Sbjct: 798 DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM--WGQEEKMWGQEEKMWGQEEKMEEK 855
Query: 267 LQKVLEEKMNAEQQLQSTQRSLALAEQK 294
+Q E+ E++++ + + E+K
Sbjct: 856 MQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 30.4 bits (67), Expect = 4.2
Identities = 20/99 (20%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Query: 219 EDKLKG---KLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKM 275
E+K++G K+R E ++ +K WG ++ + E++ E+K +K+ E+
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKM--WGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQ 857
Query: 276 NAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGT 314
E++++ + + E+K E + +E +G+
Sbjct: 858 GQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVGS 896
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 65.5 bits (158), Expect = 1e-10
Identities = 86/339 (25%), Positives = 150/339 (44%), Gaps = 51/339 (15%)
Query: 175 IQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLY 234
++ ++ K L+++ L++K +LQ+L L Q +S K + +K + LE +
Sbjct: 387 LEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVK 446
Query: 235 TCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQK 294
Q S K L + QK K SL++ +++ A QQ + ALA
Sbjct: 447 EAKQDKSKEAECKAL-------QAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCH 499
Query: 295 CEEW-RSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRD-----------LQMNQ 342
E+ R + L D + T +EL+ +L +LQ + A+ L++++
Sbjct: 500 LEDTQRKLQKGLLLDKQKADTI-QELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSE 558
Query: 343 ALRFLEN---EHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGL 399
ALR LEN E +QLQ + ++D+ D+ D++K E+ ++ ++++
Sbjct: 559 ALRKLENSDKEKRQLQKTV----AEQDM---KMNDMLDRIKHQHREQGSIKCKLEE---- 607
Query: 400 LQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
LQE KLL K + L KS +E EG + LR + +KK L+
Sbjct: 608 ------DLQEATKLLEDKREQLK----KSKEHEKLMEGELEA----LRQEFKKKDKTLK- 652
Query: 460 KEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQL 498
+ R+L E +NL E C +L+ + N SQQ+
Sbjct: 653 --ENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQV 689
Score = 50.4 bits (119), Expect = 4e-06
Identities = 86/409 (21%), Positives = 158/409 (38%), Gaps = 44/409 (10%)
Query: 41 TCRQVGKTLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTS 100
T +++ + L++ Q+E + Q R+R EL + + +R Q T
Sbjct: 520 TIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAE 579
Query: 101 SEV--------FPAQHPPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHR-------- 144
++ QH I L + L L + +KK +H +
Sbjct: 580 QDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEA 639
Query: 145 -GTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLS 203
+ K + T+K + S++ L E+ S L+ +L + +Q ++QDL
Sbjct: 640 LRQEFKKKDKTLKEN-SRKLEEENENLRAELQCCSTQLESSLNKYNTSQQ---VIQDLNK 695
Query: 204 TLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKA 263
+ +S Q DK L+ ++ L T K + + + +D +A
Sbjct: 696 EIALQKESLMSLQAQLDKA---LQKEKHYLQTTITKEAYDALSRKSAACQDDLT----QA 748
Query: 264 KESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQL 323
E L V E + +Q L TQ A E++ + + + L + R L H+E E ++
Sbjct: 749 LEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEV 808
Query: 324 HVLQSKLQGADSRDLQMNQA----LRFLENEHQQLQ--------AKIECLQGDRDLCSLD 371
H KL+ + LQ + L+ L + +QL+ K L+ D++ C L
Sbjct: 809 HAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLP 868
Query: 372 TQDLQDQLKRSEAEKLTLVTRVQQ--LQGLLQNQSL--QLQEQEKLLTK 416
+ R ++T ++Q Q + N+ L QL+EQ K + K
Sbjct: 869 QWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAK 917
Score = 50.1 bits (118), Expect = 5e-06
Identities = 84/377 (22%), Positives = 156/377 (41%), Gaps = 47/377 (12%)
Query: 153 PTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSS 212
P K D S+ Y + +E + L E Q+ + Q+ ++Q+L + L ++
Sbjct: 214 PENKGDHSKVRIYTSPCMIQEHQETQKRLSEVWQK---VSQQDDLIQELRNKLACSNALV 270
Query: 213 WKGQLNEDKLKGKLRSLENQLYTCTQKYSPWG------MKKVLLEMEDQKNS-------Y 259
+ + KL+ S T T +Y P +KK+L +++QK+S Y
Sbjct: 271 LEREKALIKLQADFASC-----TATHRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEY 325
Query: 260 EQKAKE---SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQH 316
+ K+ L+ V E+K N + + + L EE + E +D L +
Sbjct: 326 QNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLR---EETSAHIERKDKDITILQCRL 382
Query: 317 RELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQ----------AKIECLQGDRD 366
+EL+ + Q D + ++ L+ LE + Q+Q K +C+ + +
Sbjct: 383 QELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELE 442
Query: 367 LCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQN--QSLQLQEQEKLLTKKDQALPVW 424
+ + + Q K EAE L VQ+L+ L+ Q +L Q+ K++ AL
Sbjct: 443 MTVKEAK----QDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGC 498
Query: 425 SPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK----EKECRELHSELDNLSDEYLS 480
+ +++ ++ D +LQ++ LQ + EKE ++ LS E
Sbjct: 499 HLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSE 558
Query: 481 CLRKLQHCREELNQSQQ 497
LRKL++ +E Q Q+
Sbjct: 559 ALRKLENSDKEKRQLQK 575
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 65.5 bits (158), Expect = 1e-10
Identities = 80/354 (22%), Positives = 149/354 (42%), Gaps = 51/354 (14%)
Query: 161 QQTNYGVAVLDKEIIQLSDYLK-------------EALQRELVLKQKMVILQDLLSTLIQ 207
++ +A LD EI Q ++ LK E L E + K + L ++
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 208 ASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESL 267
A + + L+ + +LR+ Q T +K ++++ S+E + +E
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKK-----------ALDEETRSHEAQVQEMR 1198
Query: 268 QKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRE-------LE 320
QK + +QL+ +R+ A ++ + + L + R LG +E LE
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 321 SQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGD-----RDLCSLDT--Q 373
+Q+ LQSK + ++N + L+NE + + + +G +D+ SL + Q
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ 1318
Query: 374 DLQDQLKRSEAEKLTLVTRVQQLQ---GLLQNQSLQLQEQEKLLTKKDQALPVWSPKS-- 428
D Q+ L+ +KL + T+++QL+ LQ+Q + E ++ L + L + S
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 429 ----FPNEVEPEGTGKEKDW----DLRDQLQKKTLQLQAKEKECRELHSELDNL 474
F + VE GK++ +L Q ++K EK L ELD+L
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Score = 55.1 bits (131), Expect = 2e-07
Identities = 61/297 (20%), Positives = 130/297 (43%), Gaps = 19/297 (6%)
Query: 205 LIQASDSSWKGQLNEDKL---KGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQ 261
L+Q + + Q ED+L K + + EN+L QK+S +K LL+ + Q +
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 262 KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELES 321
E ++ L K +Q+L+ + E + EE + + L+ + + + Q +LE
Sbjct: 904 AEAEEMRVRLAAK---KQELEEILHEM---EARLEEEEDRGQQLQAERKKMAQQMLDLEE 957
Query: 322 QLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKR 381
QL ++ Q + ++ LE+E + + L +R L DL L
Sbjct: 958 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE 1017
Query: 382 SEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTG-K 440
E + L + + ++ ++L+++EK + ++ ++E + +
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK---------LKRKLEGDASDFH 1068
Query: 441 EKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E+ DL+ Q+ + +QL KE+E + + LD+ + + L+K++ ++ Q+
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Score = 53.5 bits (127), Expect = 5e-07
Identities = 112/516 (21%), Positives = 216/516 (41%), Gaps = 56/516 (10%)
Query: 12 LARWAESYEAKCERRQEI-RESRRCRPNVTT-CRQVGK---TLRIQQREQLQ-RARLQQF 65
LA+ S ++ + QE+ +E R + NV+T RQ+ + +L+ Q E+++ + L++
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 66 FRRRNLELEEKGK-----AQHPQAREQGPSRRPGQVTGTSS--EVFPAQHPPPSGICRDL 118
N++L + K A +A E+G R ++ + E A + L
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 119 SDHLSSQAGGLPPQDTPIKKPPKHHRG-TQTKAEGPTIKNDASQQTNYGVAVL---DKEI 174
L L Q + K R Q AE I + + + + A + +
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 175 IQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLY 234
+ L+ L+EAL+ + L++ +L+ + L+ + D K N +L+ R+LE Q+
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQME 1542
Query: 235 TCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNA-----EQQLQSTQRSLA 289
MK L E+ED E +A E + LE M A E+ LQ+
Sbjct: 1543 E---------MKTQLEELED-----ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1588
Query: 290 LAEQKCEEWRSQYEALKEDWRT----LGTQHRELESQLHVLQSKLQGADSRDLQMNQALR 345
++ + +YE ED R ++LE L L+ + A + + LR
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 346 FLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSL 405
L+ + + Q ++E + RD ++ K +E + +L + QLQ L +
Sbjct: 1649 KLQAQMKDFQRELEDARASRD-------EIFATAKENEKKAKSLEADLMQLQEDL--AAA 1699
Query: 406 QLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKE-KDWDLRDQLQKKTLQLQAKEKEC 464
+ ++ L K++ A + S S N ++ E E + L ++L+++ ++A
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 465 RELHSELDNLSDEYL---SCLRKLQHCREELNQSQQ 497
R+ + + LS+E S +K + R++L + +
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Score = 50.8 bits (120), Expect = 3e-06
Identities = 87/393 (22%), Positives = 165/393 (41%), Gaps = 86/393 (21%)
Query: 145 GTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLST 204
G +AEG IK VA L ++ + L+E +++L + K+ L++ ++
Sbjct: 1294 GMLNEAEGKAIKLAKD------VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 205 LIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPW---------GMKKVLLEMEDQ 255
L D + + N L+ + +L QL +K + G K+ E+E+
Sbjct: 1348 LQDQLDEEMEAKQN---LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 256 KNSYEQKA---------KESLQKVLEEKM----NAEQ---QLQSTQRSL--ALAEQKC-- 295
YE+KA K LQ+ L++ + N Q L+ QR LAE+K
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 296 -----EEWRSQYEALKEDWRTLGTQH---------RELESQLHVLQSKLQGADSRDLQMN 341
E R++ EA +++ + L ELE +L+++++ S +
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
Query: 342 QALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQ 401
+ + LE + L+ ++E ++ ++L+D+L+ +E KL L +Q L+G +
Sbjct: 1525 KNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQALKGQFE 1577
Query: 402 N--QSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
Q+ Q +EK + Q E + +L D+ +++ L A
Sbjct: 1578 RDLQARDEQNEEKRRQLQRQL-------------------HEYETELEDERKQRALAAAA 1618
Query: 460 KEK---ECRELHSELDNL---SDEYLSCLRKLQ 486
K+K + ++L + D+ +E + LRKLQ
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Score = 42.7 bits (99), Expect = 8e-04
Identities = 81/327 (24%), Positives = 128/327 (39%), Gaps = 63/327 (19%)
Query: 183 EALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSP 242
E QR L K + DL +QA DS+ KG+ E+ +K +LR L+ Q
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGR--EEAIK-QLRKLQAQ---------- 1653
Query: 243 WGMKKVLLEMEDQKNSYEQ---KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
MK E+ED + S ++ AKE+ +K + E L Q LA AE+ ++
Sbjct: 1654 --MKDFQRELEDARASRDEIFATAKENEKKA----KSLEADLMQLQEDLAAAERARKQAD 1707
Query: 300 SQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
+ E L E+ L S L G ++ + R LE QL+ ++E
Sbjct: 1708 LEKEELAEE-----------------LASSLSGRNA----LQDEKRRLEARIAQLEEELE 1746
Query: 360 CLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
QG+ + S + Q ++ E T + Q+ + Q QL+ Q K L K
Sbjct: 1747 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ----QLERQNKELRSKLH 1802
Query: 420 ALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK-EKECRELHSELDNLSDEY 478
E EG K K L+ K QL+ + E+E RE + +L +
Sbjct: 1803 --------------EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 479 LSCLRKLQHCREELNQSQQLPPRRQCG 505
L +E ++Q + + G
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKG 1875
Score = 30.4 bits (67), Expect = 4.2
Identities = 58/337 (17%), Positives = 132/337 (39%), Gaps = 35/337 (10%)
Query: 49 LRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQH 108
LR++ Q + + ++ + R+ + EEK + Q E + + A
Sbjct: 1563 LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER---KQRALAAAAK 1619
Query: 109 PPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKND----ASQQTN 164
G +DL S G ++K + Q + E D +++
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
Query: 165 YGVAVLDKEIIQLSDYLKEALQ-RELVLKQKMVILQDLLSTL------------IQASDS 211
L+ +++QL + L A + R+ +K + ++L S+L ++A +
Sbjct: 1680 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Query: 212 SWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVL 271
+ +L E++ G + ++ +++ TQ+ + QKN ++ E K L
Sbjct: 1740 QLEEELEEEQ--GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1797
Query: 272 EEKMN-----AEQQLQSTQRSLAL--------AEQKCEEWRSQYEALKEDWRTLGTQHRE 318
K++ + + +ST +L EQ+ E ++ ++LK+ + L +
Sbjct: 1798 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1857
Query: 319 LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQ 355
+E + + + + A+ + ++ Q R LE ++ Q
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1894
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 65.5 bits (158), Expect = 1e-10
Identities = 80/354 (22%), Positives = 149/354 (42%), Gaps = 51/354 (14%)
Query: 161 QQTNYGVAVLDKEIIQLSDYLK-------------EALQRELVLKQKMVILQDLLSTLIQ 207
++ +A LD EI Q ++ LK E L E + K + L ++
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 208 ASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESL 267
A + + L+ + +LR+ Q T +K ++++ S+E + +E
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKK-----------ALDEETRSHEAQVQEMR 1205
Query: 268 QKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRE-------LE 320
QK + +QL+ +R+ A ++ + + L + R LG +E LE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 321 SQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGD-----RDLCSLDT--Q 373
+Q+ LQSK + ++N + L+NE + + + +G +D+ SL + Q
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ 1325
Query: 374 DLQDQLKRSEAEKLTLVTRVQQLQ---GLLQNQSLQLQEQEKLLTKKDQALPVWSPKS-- 428
D Q+ L+ +KL + T+++QL+ LQ+Q + E ++ L + L + S
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 429 ----FPNEVEPEGTGKEKDW----DLRDQLQKKTLQLQAKEKECRELHSELDNL 474
F + VE GK++ +L Q ++K EK L ELD+L
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Score = 55.1 bits (131), Expect = 2e-07
Identities = 61/297 (20%), Positives = 130/297 (43%), Gaps = 19/297 (6%)
Query: 205 LIQASDSSWKGQLNEDKL---KGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQ 261
L+Q + + Q ED+L K + + EN+L QK+S +K LL+ + Q +
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 262 KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELES 321
E ++ L K +Q+L+ + E + EE + + L+ + + + Q +LE
Sbjct: 911 AEAEEMRVRLAAK---KQELEEILHEM---EARLEEEEDRGQQLQAERKKMAQQMLDLEE 964
Query: 322 QLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKR 381
QL ++ Q + ++ LE+E + + L +R L DL L
Sbjct: 965 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE 1024
Query: 382 SEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTG-K 440
E + L + + ++ ++L+++EK + ++ ++E + +
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK---------LKRKLEGDASDFH 1075
Query: 441 EKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E+ DL+ Q+ + +QL KE+E + + LD+ + + L+K++ ++ Q+
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Score = 53.5 bits (127), Expect = 5e-07
Identities = 112/516 (21%), Positives = 216/516 (41%), Gaps = 56/516 (10%)
Query: 12 LARWAESYEAKCERRQEI-RESRRCRPNVTT-CRQVGK---TLRIQQREQLQ-RARLQQF 65
LA+ S ++ + QE+ +E R + NV+T RQ+ + +L+ Q E+++ + L++
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 66 FRRRNLELEEKGK-----AQHPQAREQGPSRRPGQVTGTSS--EVFPAQHPPPSGICRDL 118
N++L + K A +A E+G R ++ + E A + L
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 119 SDHLSSQAGGLPPQDTPIKKPPKHHRG-TQTKAEGPTIKNDASQQTNYGVAVL---DKEI 174
L L Q + K R Q AE I + + + + A + +
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 175 IQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLY 234
+ L+ L+EAL+ + L++ +L+ + L+ + D K N +L+ R+LE Q+
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQME 1549
Query: 235 TCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNA-----EQQLQSTQRSLA 289
MK L E+ED E +A E + LE M A E+ LQ+
Sbjct: 1550 E---------MKTQLEELED-----ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1595
Query: 290 LAEQKCEEWRSQYEALKEDWRT----LGTQHRELESQLHVLQSKLQGADSRDLQMNQALR 345
++ + +YE ED R ++LE L L+ + A + + LR
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 346 FLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSL 405
L+ + + Q ++E + RD ++ K +E + +L + QLQ L +
Sbjct: 1656 KLQAQMKDFQRELEDARASRD-------EIFATAKENEKKAKSLEADLMQLQEDL--AAA 1706
Query: 406 QLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKE-KDWDLRDQLQKKTLQLQAKEKEC 464
+ ++ L K++ A + S S N ++ E E + L ++L+++ ++A
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 465 RELHSELDNLSDEYL---SCLRKLQHCREELNQSQQ 497
R+ + + LS+E S +K + R++L + +
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1802
Score = 50.8 bits (120), Expect = 3e-06
Identities = 87/393 (22%), Positives = 165/393 (41%), Gaps = 86/393 (21%)
Query: 145 GTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLST 204
G +AEG IK VA L ++ + L+E +++L + K+ L++ ++
Sbjct: 1301 GMLNEAEGKAIKLAKD------VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 205 LIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPW---------GMKKVLLEMEDQ 255
L D + + N L+ + +L QL +K + G K+ E+E+
Sbjct: 1355 LQDQLDEEMEAKQN---LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 256 KNSYEQKA---------KESLQKVLEEKM----NAEQ---QLQSTQRSL--ALAEQKC-- 295
YE+KA K LQ+ L++ + N Q L+ QR LAE+K
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 296 -----EEWRSQYEALKEDWRTLGTQH---------RELESQLHVLQSKLQGADSRDLQMN 341
E R++ EA +++ + L ELE +L+++++ S +
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1531
Query: 342 QALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQ 401
+ + LE + L+ ++E ++ ++L+D+L+ +E KL L +Q L+G +
Sbjct: 1532 KNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQALKGQFE 1584
Query: 402 N--QSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
Q+ Q +EK + Q E + +L D+ +++ L A
Sbjct: 1585 RDLQARDEQNEEKRRQLQRQL-------------------HEYETELEDERKQRALAAAA 1625
Query: 460 KEK---ECRELHSELDNL---SDEYLSCLRKLQ 486
K+K + ++L + D+ +E + LRKLQ
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Score = 42.7 bits (99), Expect = 8e-04
Identities = 81/327 (24%), Positives = 128/327 (39%), Gaps = 63/327 (19%)
Query: 183 EALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSP 242
E QR L K + DL +QA DS+ KG+ E+ +K +LR L+ Q
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGR--EEAIK-QLRKLQAQ---------- 1660
Query: 243 WGMKKVLLEMEDQKNSYEQ---KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
MK E+ED + S ++ AKE+ +K + E L Q LA AE+ ++
Sbjct: 1661 --MKDFQRELEDARASRDEIFATAKENEKKA----KSLEADLMQLQEDLAAAERARKQAD 1714
Query: 300 SQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
+ E L E+ L S L G ++ + R LE QL+ ++E
Sbjct: 1715 LEKEELAEE-----------------LASSLSGRNA----LQDEKRRLEARIAQLEEELE 1753
Query: 360 CLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
QG+ + S + Q ++ E T + Q+ + Q QL+ Q K L K
Sbjct: 1754 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ----QLERQNKELRSKLH 1809
Query: 420 ALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK-EKECRELHSELDNLSDEY 478
E EG K K L+ K QL+ + E+E RE + +L +
Sbjct: 1810 --------------EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 479 LSCLRKLQHCREELNQSQQLPPRRQCG 505
L +E ++Q + + G
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKG 1882
Score = 30.4 bits (67), Expect = 4.2
Identities = 58/337 (17%), Positives = 132/337 (39%), Gaps = 35/337 (10%)
Query: 49 LRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQH 108
LR++ Q + + ++ + R+ + EEK + Q E + + A
Sbjct: 1570 LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER---KQRALAAAAK 1626
Query: 109 PPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKND----ASQQTN 164
G +DL S G ++K + Q + E D +++
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1686
Query: 165 YGVAVLDKEIIQLSDYLKEALQ-RELVLKQKMVILQDLLSTL------------IQASDS 211
L+ +++QL + L A + R+ +K + ++L S+L ++A +
Sbjct: 1687 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Query: 212 SWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVL 271
+ +L E++ G + ++ +++ TQ+ + QKN ++ E K L
Sbjct: 1747 QLEEELEEEQ--GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1804
Query: 272 EEKMN-----AEQQLQSTQRSLAL--------AEQKCEEWRSQYEALKEDWRTLGTQHRE 318
K++ + + +ST +L EQ+ E ++ ++LK+ + L +
Sbjct: 1805 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1864
Query: 319 LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQ 355
+E + + + + A+ + ++ Q R LE ++ Q
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1901
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 65.5 bits (158), Expect = 1e-10
Identities = 80/354 (22%), Positives = 149/354 (42%), Gaps = 51/354 (14%)
Query: 161 QQTNYGVAVLDKEIIQLSDYLK-------------EALQRELVLKQKMVILQDLLSTLIQ 207
++ +A LD EI Q ++ LK E L E + K + L ++
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 208 ASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESL 267
A + + L+ + +LR+ Q T +K ++++ S+E + +E
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKK-----------ALDEETRSHEAQVQEMR 1205
Query: 268 QKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRE-------LE 320
QK + +QL+ +R+ A ++ + + L + R LG +E LE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 321 SQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGD-----RDLCSLDT--Q 373
+Q+ LQSK + ++N + L+NE + + + +G +D+ SL + Q
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ 1325
Query: 374 DLQDQLKRSEAEKLTLVTRVQQLQ---GLLQNQSLQLQEQEKLLTKKDQALPVWSPKS-- 428
D Q+ L+ +KL + T+++QL+ LQ+Q + E ++ L + L + S
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 429 ----FPNEVEPEGTGKEKDW----DLRDQLQKKTLQLQAKEKECRELHSELDNL 474
F + VE GK++ +L Q ++K EK L ELD+L
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Score = 55.1 bits (131), Expect = 2e-07
Identities = 61/297 (20%), Positives = 130/297 (43%), Gaps = 19/297 (6%)
Query: 205 LIQASDSSWKGQLNEDKL---KGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQ 261
L+Q + + Q ED+L K + + EN+L QK+S +K LL+ + Q +
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 262 KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELES 321
E ++ L K +Q+L+ + E + EE + + L+ + + + Q +LE
Sbjct: 911 AEAEEMRVRLAAK---KQELEEILHEM---EARLEEEEDRGQQLQAERKKMAQQMLDLEE 964
Query: 322 QLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKR 381
QL ++ Q + ++ LE+E + + L +R L DL L
Sbjct: 965 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE 1024
Query: 382 SEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTG-K 440
E + L + + ++ ++L+++EK + ++ ++E + +
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK---------LKRKLEGDASDFH 1075
Query: 441 EKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E+ DL+ Q+ + +QL KE+E + + LD+ + + L+K++ ++ Q+
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Score = 53.5 bits (127), Expect = 5e-07
Identities = 112/516 (21%), Positives = 216/516 (41%), Gaps = 56/516 (10%)
Query: 12 LARWAESYEAKCERRQEI-RESRRCRPNVTT-CRQVGK---TLRIQQREQLQ-RARLQQF 65
LA+ S ++ + QE+ +E R + NV+T RQ+ + +L+ Q E+++ + L++
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 66 FRRRNLELEEKGK-----AQHPQAREQGPSRRPGQVTGTSS--EVFPAQHPPPSGICRDL 118
N++L + K A +A E+G R ++ + E A + L
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 119 SDHLSSQAGGLPPQDTPIKKPPKHHRG-TQTKAEGPTIKNDASQQTNYGVAVL---DKEI 174
L L Q + K R Q AE I + + + + A + +
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 175 IQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLY 234
+ L+ L+EAL+ + L++ +L+ + L+ + D K N +L+ R+LE Q+
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQME 1549
Query: 235 TCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNA-----EQQLQSTQRSLA 289
MK L E+ED E +A E + LE M A E+ LQ+
Sbjct: 1550 E---------MKTQLEELED-----ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1595
Query: 290 LAEQKCEEWRSQYEALKEDWRT----LGTQHRELESQLHVLQSKLQGADSRDLQMNQALR 345
++ + +YE ED R ++LE L L+ + A + + LR
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 346 FLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSL 405
L+ + + Q ++E + RD ++ K +E + +L + QLQ L +
Sbjct: 1656 KLQAQMKDFQRELEDARASRD-------EIFATAKENEKKAKSLEADLMQLQEDL--AAA 1706
Query: 406 QLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKE-KDWDLRDQLQKKTLQLQAKEKEC 464
+ ++ L K++ A + S S N ++ E E + L ++L+++ ++A
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 465 RELHSELDNLSDEYL---SCLRKLQHCREELNQSQQ 497
R+ + + LS+E S +K + R++L + +
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1802
Score = 50.8 bits (120), Expect = 3e-06
Identities = 87/393 (22%), Positives = 165/393 (41%), Gaps = 86/393 (21%)
Query: 145 GTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLST 204
G +AEG IK VA L ++ + L+E +++L + K+ L++ ++
Sbjct: 1301 GMLNEAEGKAIKLAKD------VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 205 LIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPW---------GMKKVLLEMEDQ 255
L D + + N L+ + +L QL +K + G K+ E+E+
Sbjct: 1355 LQDQLDEEMEAKQN---LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 256 KNSYEQKA---------KESLQKVLEEKM----NAEQ---QLQSTQRSL--ALAEQKC-- 295
YE+KA K LQ+ L++ + N Q L+ QR LAE+K
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 296 -----EEWRSQYEALKEDWRTLGTQH---------RELESQLHVLQSKLQGADSRDLQMN 341
E R++ EA +++ + L ELE +L+++++ S +
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1531
Query: 342 QALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQ 401
+ + LE + L+ ++E ++ ++L+D+L+ +E KL L +Q L+G +
Sbjct: 1532 KNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQALKGQFE 1584
Query: 402 N--QSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
Q+ Q +EK + Q E + +L D+ +++ L A
Sbjct: 1585 RDLQARDEQNEEKRRQLQRQL-------------------HEYETELEDERKQRALAAAA 1625
Query: 460 KEK---ECRELHSELDNL---SDEYLSCLRKLQ 486
K+K + ++L + D+ +E + LRKLQ
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Score = 42.7 bits (99), Expect = 8e-04
Identities = 81/327 (24%), Positives = 128/327 (39%), Gaps = 63/327 (19%)
Query: 183 EALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSP 242
E QR L K + DL +QA DS+ KG+ E+ +K +LR L+ Q
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGR--EEAIK-QLRKLQAQ---------- 1660
Query: 243 WGMKKVLLEMEDQKNSYEQ---KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
MK E+ED + S ++ AKE+ +K + E L Q LA AE+ ++
Sbjct: 1661 --MKDFQRELEDARASRDEIFATAKENEKKA----KSLEADLMQLQEDLAAAERARKQAD 1714
Query: 300 SQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
+ E L E+ L S L G ++ + R LE QL+ ++E
Sbjct: 1715 LEKEELAEE-----------------LASSLSGRNA----LQDEKRRLEARIAQLEEELE 1753
Query: 360 CLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
QG+ + S + Q ++ E T + Q+ + Q QL+ Q K L K
Sbjct: 1754 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ----QLERQNKELRSKLH 1809
Query: 420 ALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK-EKECRELHSELDNLSDEY 478
E EG K K L+ K QL+ + E+E RE + +L +
Sbjct: 1810 --------------EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 479 LSCLRKLQHCREELNQSQQLPPRRQCG 505
L +E ++Q + + G
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKG 1882
Score = 38.5 bits (88), Expect = 0.015
Identities = 30/163 (18%), Positives = 85/163 (52%), Gaps = 9/163 (5%)
Query: 171 DKEIIQLSDYLKEALQRE-LVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSL 229
++ Q ++ ++ L+R+ L+ K+ ++ + + +++ ++ + ++ + + + + +
Sbjct: 1783 ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1842
Query: 230 ENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLA 289
E Q T + K +K++LL++ED++ EQ +++ EK NA +++ +R L
Sbjct: 1843 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA------EKGNA--RVKQLKRQLE 1894
Query: 290 LAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQG 332
AE++ + + L+ + + + +++ L+SKL+G
Sbjct: 1895 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 1937
Score = 30.4 bits (67), Expect = 4.2
Identities = 58/337 (17%), Positives = 132/337 (39%), Gaps = 35/337 (10%)
Query: 49 LRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQH 108
LR++ Q + + ++ + R+ + EEK + Q E + + A
Sbjct: 1570 LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER---KQRALAAAAK 1626
Query: 109 PPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKND----ASQQTN 164
G +DL S G ++K + Q + E D +++
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1686
Query: 165 YGVAVLDKEIIQLSDYLKEALQ-RELVLKQKMVILQDLLSTL------------IQASDS 211
L+ +++QL + L A + R+ +K + ++L S+L ++A +
Sbjct: 1687 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Query: 212 SWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVL 271
+ +L E++ G + ++ +++ TQ+ + QKN ++ E K L
Sbjct: 1747 QLEEELEEEQ--GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1804
Query: 272 EEKMN-----AEQQLQSTQRSLAL--------AEQKCEEWRSQYEALKEDWRTLGTQHRE 318
K++ + + +ST +L EQ+ E ++ ++LK+ + L +
Sbjct: 1805 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1864
Query: 319 LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQ 355
+E + + + + A+ + ++ Q R LE ++ Q
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1901
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 65.5 bits (158), Expect = 1e-10
Identities = 80/354 (22%), Positives = 149/354 (42%), Gaps = 51/354 (14%)
Query: 161 QQTNYGVAVLDKEIIQLSDYLK-------------EALQRELVLKQKMVILQDLLSTLIQ 207
++ +A LD EI Q ++ LK E L E + K + L ++
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 208 ASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESL 267
A + + L+ + +LR+ Q T +K ++++ S+E + +E
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKK-----------ALDEETRSHEAQVQEMR 1198
Query: 268 QKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRE-------LE 320
QK + +QL+ +R+ A ++ + + L + R LG +E LE
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 321 SQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGD-----RDLCSLDT--Q 373
+Q+ LQSK + ++N + L+NE + + + +G +D+ SL + Q
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ 1318
Query: 374 DLQDQLKRSEAEKLTLVTRVQQLQ---GLLQNQSLQLQEQEKLLTKKDQALPVWSPKS-- 428
D Q+ L+ +KL + T+++QL+ LQ+Q + E ++ L + L + S
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 429 ----FPNEVEPEGTGKEKDW----DLRDQLQKKTLQLQAKEKECRELHSELDNL 474
F + VE GK++ +L Q ++K EK L ELD+L
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Score = 55.1 bits (131), Expect = 2e-07
Identities = 61/297 (20%), Positives = 130/297 (43%), Gaps = 19/297 (6%)
Query: 205 LIQASDSSWKGQLNEDKL---KGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQ 261
L+Q + + Q ED+L K + + EN+L QK+S +K LL+ + Q +
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 262 KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELES 321
E ++ L K +Q+L+ + E + EE + + L+ + + + Q +LE
Sbjct: 904 AEAEEMRVRLAAK---KQELEEILHEM---EARLEEEEDRGQQLQAERKKMAQQMLDLEE 957
Query: 322 QLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKR 381
QL ++ Q + ++ LE+E + + L +R L DL L
Sbjct: 958 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE 1017
Query: 382 SEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTG-K 440
E + L + + ++ ++L+++EK + ++ ++E + +
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK---------LKRKLEGDASDFH 1068
Query: 441 EKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E+ DL+ Q+ + +QL KE+E + + LD+ + + L+K++ ++ Q+
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Score = 53.5 bits (127), Expect = 5e-07
Identities = 112/516 (21%), Positives = 216/516 (41%), Gaps = 56/516 (10%)
Query: 12 LARWAESYEAKCERRQEI-RESRRCRPNVTT-CRQVGK---TLRIQQREQLQ-RARLQQF 65
LA+ S ++ + QE+ +E R + NV+T RQ+ + +L+ Q E+++ + L++
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 66 FRRRNLELEEKGK-----AQHPQAREQGPSRRPGQVTGTSS--EVFPAQHPPPSGICRDL 118
N++L + K A +A E+G R ++ + E A + L
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 119 SDHLSSQAGGLPPQDTPIKKPPKHHRG-TQTKAEGPTIKNDASQQTNYGVAVL---DKEI 174
L L Q + K R Q AE I + + + + A + +
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 175 IQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLY 234
+ L+ L+EAL+ + L++ +L+ + L+ + D K N +L+ R+LE Q+
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQME 1542
Query: 235 TCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNA-----EQQLQSTQRSLA 289
MK L E+ED E +A E + LE M A E+ LQ+
Sbjct: 1543 E---------MKTQLEELED-----ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1588
Query: 290 LAEQKCEEWRSQYEALKEDWRT----LGTQHRELESQLHVLQSKLQGADSRDLQMNQALR 345
++ + +YE ED R ++LE L L+ + A + + LR
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 346 FLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSL 405
L+ + + Q ++E + RD ++ K +E + +L + QLQ L +
Sbjct: 1649 KLQAQMKDFQRELEDARASRD-------EIFATAKENEKKAKSLEADLMQLQEDL--AAA 1699
Query: 406 QLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKE-KDWDLRDQLQKKTLQLQAKEKEC 464
+ ++ L K++ A + S S N ++ E E + L ++L+++ ++A
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 465 RELHSELDNLSDEYL---SCLRKLQHCREELNQSQQ 497
R+ + + LS+E S +K + R++L + +
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
Score = 50.8 bits (120), Expect = 3e-06
Identities = 87/393 (22%), Positives = 165/393 (41%), Gaps = 86/393 (21%)
Query: 145 GTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLST 204
G +AEG IK VA L ++ + L+E +++L + K+ L++ ++
Sbjct: 1294 GMLNEAEGKAIKLAKD------VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 205 LIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPW---------GMKKVLLEMEDQ 255
L D + + N L+ + +L QL +K + G K+ E+E+
Sbjct: 1348 LQDQLDEEMEAKQN---LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 256 KNSYEQKA---------KESLQKVLEEKM----NAEQ---QLQSTQRSL--ALAEQKC-- 295
YE+KA K LQ+ L++ + N Q L+ QR LAE+K
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 296 -----EEWRSQYEALKEDWRTLGTQH---------RELESQLHVLQSKLQGADSRDLQMN 341
E R++ EA +++ + L ELE +L+++++ S +
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
Query: 342 QALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQ 401
+ + LE + L+ ++E ++ ++L+D+L+ +E KL L +Q L+G +
Sbjct: 1525 KNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQALKGQFE 1577
Query: 402 N--QSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
Q+ Q +EK + Q E + +L D+ +++ L A
Sbjct: 1578 RDLQARDEQNEEKRRQLQRQL-------------------HEYETELEDERKQRALAAAA 1618
Query: 460 KEK---ECRELHSELDNL---SDEYLSCLRKLQ 486
K+K + ++L + D+ +E + LRKLQ
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Score = 42.7 bits (99), Expect = 8e-04
Identities = 81/327 (24%), Positives = 128/327 (39%), Gaps = 63/327 (19%)
Query: 183 EALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSP 242
E QR L K + DL +QA DS+ KG+ E+ +K +LR L+ Q
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGR--EEAIK-QLRKLQAQ---------- 1653
Query: 243 WGMKKVLLEMEDQKNSYEQ---KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
MK E+ED + S ++ AKE+ +K + E L Q LA AE+ ++
Sbjct: 1654 --MKDFQRELEDARASRDEIFATAKENEKKA----KSLEADLMQLQEDLAAAERARKQAD 1707
Query: 300 SQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
+ E L E+ L S L G ++ + R LE QL+ ++E
Sbjct: 1708 LEKEELAEE-----------------LASSLSGRNA----LQDEKRRLEARIAQLEEELE 1746
Query: 360 CLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
QG+ + S + Q ++ E T + Q+ + Q QL+ Q K L K
Sbjct: 1747 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ----QLERQNKELRSKLH 1802
Query: 420 ALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK-EKECRELHSELDNLSDEY 478
E EG K K L+ K QL+ + E+E RE + +L +
Sbjct: 1803 --------------EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 479 LSCLRKLQHCREELNQSQQLPPRRQCG 505
L +E ++Q + + G
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKG 1875
Score = 38.5 bits (88), Expect = 0.015
Identities = 30/163 (18%), Positives = 85/163 (52%), Gaps = 9/163 (5%)
Query: 171 DKEIIQLSDYLKEALQRE-LVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSL 229
++ Q ++ ++ L+R+ L+ K+ ++ + + +++ ++ + ++ + + + + +
Sbjct: 1776 ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1835
Query: 230 ENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLA 289
E Q T + K +K++LL++ED++ EQ +++ EK NA +++ +R L
Sbjct: 1836 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA------EKGNA--RVKQLKRQLE 1887
Query: 290 LAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQG 332
AE++ + + L+ + + + +++ L+SKL+G
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 1930
Score = 30.4 bits (67), Expect = 4.2
Identities = 58/337 (17%), Positives = 132/337 (39%), Gaps = 35/337 (10%)
Query: 49 LRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQH 108
LR++ Q + + ++ + R+ + EEK + Q E + + A
Sbjct: 1563 LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER---KQRALAAAAK 1619
Query: 109 PPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKND----ASQQTN 164
G +DL S G ++K + Q + E D +++
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
Query: 165 YGVAVLDKEIIQLSDYLKEALQ-RELVLKQKMVILQDLLSTL------------IQASDS 211
L+ +++QL + L A + R+ +K + ++L S+L ++A +
Sbjct: 1680 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Query: 212 SWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVL 271
+ +L E++ G + ++ +++ TQ+ + QKN ++ E K L
Sbjct: 1740 QLEEELEEEQ--GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1797
Query: 272 EEKMN-----AEQQLQSTQRSLAL--------AEQKCEEWRSQYEALKEDWRTLGTQHRE 318
K++ + + +ST +L EQ+ E ++ ++LK+ + L +
Sbjct: 1798 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1857
Query: 319 LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQ 355
+E + + + + A+ + ++ Q R LE ++ Q
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1894
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 64.7 bits (156), Expect = 2e-10
Identities = 89/424 (20%), Positives = 194/424 (45%), Gaps = 44/424 (10%)
Query: 81 HPQAREQGPSRRPGQVTGTSSE--------VFPAQHPPPSGI--CRDLSDHLSSQAGGLP 130
HP P +++G+S++ +F + P I R+ + L Q L
Sbjct: 190 HPGLLNYSPYENVCKISGSSTDFQKKPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLV 249
Query: 131 PQDTPI--KKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRE 188
Q+ + K H TQ++A+ + +++QQ V +L+++II L E ++
Sbjct: 250 TQNHSLMTKFESIHFELTQSRAKVSML--ESAQQQAASVPILEEQIINLE---AEVSAQD 304
Query: 189 LVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKV 248
VL++ L+ +I+ S + + E+ +K K+ LE T K + +
Sbjct: 305 KVLREAENKLEQSQKMVIEKEQSLQESK--EECIKLKVDLLEQ---TKQGKRAERQRNEA 359
Query: 249 LLEMEDQKNSYEQ---KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEAL 305
L E+ +++Q K E L+KV E+ E+ L + ++ +++C ++S+ E L
Sbjct: 360 LYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEIL 419
Query: 306 KEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDR 365
KE R L ++ + +L ++ K ++ + Q++ LE+E L+ K E L R
Sbjct: 420 KEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESE---LENKDEIL---R 473
Query: 366 DLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWS 425
D SL ++ + +++ + + R+ Q +++ ++L+ EK++++ ++
Sbjct: 474 DKFSLMNENRELKVRVAAQNE-----RLDLCQQEIESSRVELRSLEKIISQLPLKRELFG 528
Query: 426 PKSFPNEVEPEGTGKEKDWDL------RDQLQKKTLQLQAKEKECRELHSEL--DNLSDE 477
KS+ ++ + ++D + + + + ++L KE E ++LH+ L + LS
Sbjct: 529 FKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQS 588
Query: 478 YLSC 481
++C
Sbjct: 589 LITC 592
Score = 59.7 bits (143), Expect = 6e-09
Identities = 82/389 (21%), Positives = 171/389 (43%), Gaps = 44/389 (11%)
Query: 114 ICRD-LSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDK 172
IC++ L HL+ G + +KK + Q + + IKN + Q+T+ +L
Sbjct: 853 ICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELK---IKNHSLQETSEQNVILQH 909
Query: 173 EIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQ 232
+ Q L++ R L+ L+ +S L Q Q + KLR +E +
Sbjct: 910 TLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQEL------QKQRESSAEKLRKMEEK 963
Query: 233 LYTCTQKYSPWGMKKVLLEMEDQKNSYEQ-KAKESLQKVLEEKMNAEQQLQSTQRSLALA 291
+ + K + L ++ E + KE L K+ +E M+ ++ ++ L+
Sbjct: 964 CESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQL 1023
Query: 292 EQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRF-LENE 350
+ ++ +++ E +ELE H +++L A LQ + L L+N
Sbjct: 1024 DMILDQTKTELEKKT-------NAVKELEKLQHSTETELTEA----LQKREVLETELQNA 1072
Query: 351 HQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQ 410
H +L++ + L Q+L+D L++++ T ++ L L+ ++++++
Sbjct: 1073 HGELKSTLRQL-----------QELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDK 1121
Query: 411 EKLLTKKDQALPV--WSPKSFPNEV-EPEGTGKEKDWDLRDQLQKKTLQLQAKEKECREL 467
++ L + DQAL W K +V + T +E ++ ++ K L+ E E +E
Sbjct: 1122 KQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKEC 1181
Query: 468 HSELDNLSDEYLSCLRKLQHCREELNQSQ 496
+ ++++L+D KLQ+ +E+L + +
Sbjct: 1182 NKQIESLND-------KLQNAKEQLREKE 1203
Score = 57.8 bits (138), Expect = 2e-08
Identities = 62/261 (23%), Positives = 124/261 (47%), Gaps = 20/261 (7%)
Query: 251 EMEDQKNSYEQKAKESLQK--VLE-EKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKE 307
E+E ++S E + E+LQK VLE E NA +L+ST R L ++ + + +L+E
Sbjct: 1043 ELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQL---QELRDVLQKAQLSLEE 1099
Query: 308 DWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECL----QG 363
+ T+ ++L ++L + +++ L+M+QAL+ E +Q A++ L +
Sbjct: 1100 KYTTI----KDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIRE 1155
Query: 364 DRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPV 423
R L+ L++SE E +++ L LQN QL+E+E ++ + +Q +
Sbjct: 1156 HRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQ 1215
Query: 424 WS---PKSFPNEVEPEGTGKEKDWDLRDQLQKKT---LQLQAKEKECRELHSELDNLSDE 477
++ E E KE++ + Q ++ +L+ ++ + H+EL +
Sbjct: 1216 LKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQ 1275
Query: 478 YLSCLRKLQHCREELNQSQQL 498
+ R+++ EL +QL
Sbjct: 1276 QVQAQREIERLSSELEDMKQL 1296
Score = 51.2 bits (121), Expect = 2e-06
Identities = 69/337 (20%), Positives = 141/337 (41%), Gaps = 52/337 (15%)
Query: 154 TIKNDASQQTNYGVAVLDK--EIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDS 211
TIK+ ++ + + DK E++++ LKE R LKQ+ + L T+ +
Sbjct: 1103 TIKDLTAELRECKMEIEDKKQELLEMDQALKE---RNWELKQRAAQVTHLDMTIREH--- 1156
Query: 212 SWKGQLNED--KLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQK 269
+G++ + KL+G L E +L C ++ + N Q AKE L++
Sbjct: 1157 --RGEMEQKIIKLEGTLEKSELELKECNKQI-------------ESLNDKLQNAKEQLRE 1201
Query: 270 VLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRE---LESQLHVL 326
+ EQ++ ++ + +Q+ +E S +KE + + TQ++E L +L +
Sbjct: 1202 KEFIMLQNEQEISQLKKEIERTQQRMKEMES---VMKEQEQYIATQYKEAIDLGQELRLT 1258
Query: 327 QSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEK 386
+ ++Q N E HQQ+QA Q + + S + +D++ K +A
Sbjct: 1259 REQVQ---------NSHTELAEARHQQVQA-----QREIERLSSELEDMKQLSKEKDAHG 1304
Query: 387 LTLV-------TRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTG 439
L R L+ +Q + +L + + L + + ++ +
Sbjct: 1305 NHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQ 1364
Query: 440 KEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSD 476
K L +QL+K L+L+ + LH ++ + ++
Sbjct: 1365 KSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNE 1401
Score = 48.9 bits (115), Expect = 1e-05
Identities = 72/329 (21%), Positives = 139/329 (42%), Gaps = 50/329 (15%)
Query: 166 GVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGK 225
G+ L ++IQ+ E ++ + + Q + L++ + +S K + K +
Sbjct: 642 GIEELRTKLIQIE---AENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQ 698
Query: 226 LRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQ 285
L +LE QL YS K LE E + + + ++ LE +N E +
Sbjct: 699 LLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRS-------LETNINTEHE----- 746
Query: 286 RSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALR 345
+ LA +K ++ + QH+E+E Q+ L+++L+ D + + + +
Sbjct: 747 -KICLAFEKAKKIHLE-------------QHKEMEKQIERLEAQLEKKDQQFKEQEKTMS 792
Query: 346 FLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSL 405
L+ + Q +E L DR L + ++ +K+ EA K LQN
Sbjct: 793 MLQQDIICKQHHLESL--DRLLTESKGEMKKENMKKDEALK------------ALQN--- 835
Query: 406 QLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECR 465
Q+ E+ + + D AL + + + + EG KEK QL+KK+ ++ +KE +
Sbjct: 836 QVSEETIKVRQLDSALEICKEELVLHLNQLEG-NKEK---FEKQLKKKSEEVYCLQKELK 891
Query: 466 ELHSELDNLSDEYLSCLRKLQHCREELNQ 494
+ L S++ + LQ ++ L Q
Sbjct: 892 IKNHSLQETSEQNVILQHTLQQQQQMLQQ 920
Score = 35.4 bits (80), Expect = 0.13
Identities = 42/201 (20%), Positives = 90/201 (44%), Gaps = 15/201 (7%)
Query: 171 DKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLI-QASDSSWKGQLNEDKLKGKLRSL 229
++EI QL ++ QR ++ M + ++T +A D + +L ++++ L
Sbjct: 1210 EQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTEL 1269
Query: 230 ENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLA 289
+ Q ++++ E+ED K K K++ L E++ A + ++ +
Sbjct: 1270 AEARHQQVQAQRE--IERLSSELEDMKQL--SKEKDAHGNHLAEELGASKVREAHLEARM 1325
Query: 290 LAEQKCEEWRSQYEALKEDWRTLGTQHRE--------LESQLHVLQSKLQGADSRDLQMN 341
AE K + ++ E+LKE + H+E +SQ +Q + + L++
Sbjct: 1326 QAEIK--KLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELE 1383
Query: 342 QALRFLENEHQQLQAKIECLQ 362
+A + N HQQ+Q + E ++
Sbjct: 1384 EAQDTVSNLHQQVQDRNEVIE 1404
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 64.3 bits (155), Expect = 3e-10
Identities = 87/445 (19%), Positives = 182/445 (40%), Gaps = 55/445 (12%)
Query: 44 QVGKTLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEV 103
Q+ T + Q E Q+ L R R LE E+ + + E+ QV S++
Sbjct: 1316 QLQDTQELLQEETRQKLNLSS--RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 104 FPAQHPPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQT 163
D + G + + KK K + E + D ++T
Sbjct: 1374 ------------ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKT 1421
Query: 164 NYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLK 223
L +E+ L+ L Q L++K LL A + S + E++ +
Sbjct: 1422 KNR---LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLL-----AEEKSISARYAEERDR 1473
Query: 224 GKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKE---SLQKVLEEKMNAEQQ 280
+ + E + + + + L E + K +E++ K+ ++ ++ K + +
Sbjct: 1474 AEAEAREKETKALS-------LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN 1526
Query: 281 LQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQ-GADSRDLQ 339
+ ++S EQ+ EE R+Q E L+++ + LE + ++++ + +RD Q
Sbjct: 1527 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586
Query: 340 MNQALRFLENEHQQLQAKIECLQGDRDLC-------SLDTQDLQDQLKRSEAEKLTLVTR 392
+ R L + ++L+A++E + R L +D +DL+ Q++ + + ++ +
Sbjct: 1587 NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646
Query: 393 VQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQK 452
+++LQ +++ +L+E +D+ F E E K + ++ QLQ+
Sbjct: 1647 LRKLQAQMKDYQRELEEAR---ASRDEI--------FAQSKESEKKLKSLEAEIL-QLQE 1694
Query: 453 KTLQLQAKEKECRELHSELDNLSDE 477
+L + E+ R E D L+DE
Sbjct: 1695 ---ELASSERARRHAEQERDELADE 1716
Score = 57.0 bits (136), Expect = 4e-08
Identities = 62/268 (23%), Positives = 127/268 (47%), Gaps = 57/268 (21%)
Query: 249 LLEMEDQKNSYEQKAKE---SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEAL 305
LL++++++ E + +E Q++LEEK +QLQ+ A + EE R++ A
Sbjct: 861 LLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA----EAEEMRARLAAK 916
Query: 306 KEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDR 365
K+ ELE LH L+S+++ + R+ + L+NE +++QA I
Sbjct: 917 KQ----------ELEEILHDLESRVEEEEERN-------QILQNEKKKMQAHI------- 952
Query: 366 DLCSLDTQDLQDQLKRSEA-------EKLTLVTRVQQLQG---LLQNQSLQLQEQEKLLT 415
QDL++QL E EK+T ++++++ LL++Q+ + +++KL+
Sbjct: 953 -------QDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM- 1004
Query: 416 KKDQALPVWSPKSFPNEVEPEGTGKEKD------WDLRDQLQKKTLQLQAKEKECRELHS 469
+ + S + E + + K ++ DL ++L+K+ Q EK R+L
Sbjct: 1005 --EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062
Query: 470 ELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E +L D+ ++ + +L + ++
Sbjct: 1063 ETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Score = 50.4 bits (119), Expect = 4e-06
Identities = 80/338 (23%), Positives = 146/338 (43%), Gaps = 36/338 (10%)
Query: 169 VLDKEIIQLSDYLKEALQRELVLKQKM-----------VILQDLLSTLIQASDSSWKGQL 217
+ +K+ + +SD L+E L++E +Q++ LQD ++ L QA K QL
Sbjct: 1028 IRNKQEVMISD-LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL-QAQIDELKLQL 1085
Query: 218 --NEDKLKGKLRSLE-------NQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQ 268
E++L+G L + N L + + + E E + +K K L
Sbjct: 1086 AKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLS 1145
Query: 269 KVLEE-KMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQ----L 323
+ LE K E L +T L ++ +E +AL+E+ + Q +++ + L
Sbjct: 1146 EELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATAL 1205
Query: 324 HVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQ-----GDRDLCSLDTQDLQDQ 378
L +L+ A + + + LE ++++L +++ LQ + LD Q +
Sbjct: 1206 EELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELH 1265
Query: 379 LKRSEAEKLT--LVTRVQQLQGLLQNQSLQLQEQEKLLTK-KDQALPVWSPKSFPNEVEP 435
K SE ++L L + +LQ L N S L+E EK K A + S E+
Sbjct: 1266 AKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQ 1325
Query: 436 EGTGKEKDWDLR-DQLQKKTLQLQAKEKECRELHSELD 472
E T ++ + R QL+++ LQ +++E E L+
Sbjct: 1326 EETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE 1363
Score = 45.8 bits (107), Expect = 1e-04
Identities = 64/298 (21%), Positives = 129/298 (43%), Gaps = 39/298 (13%)
Query: 193 QKMVILQDLLSTLIQASDSSW-KGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLE 251
Q+++ +++L+ +QA + + + +L K + LE L+ + + +L+
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
Query: 252 MEDQK-NSYEQKAKESL-------QKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYE 303
E +K ++ Q +E L QK+ EK+ AE +++ + + L E + ++ + +
Sbjct: 943 NEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
Query: 304 ALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQG 363
+++ +Q E E + L + + + L+ E Q+L+ L G
Sbjct: 1003 LMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062
Query: 364 DRDLCSLDTQDLQDQLKRSEAE----KLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
+ T DLQDQ+ +A+ KL L + ++LQG L + E L K+
Sbjct: 1063 E-------TTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG-----DDETL--HKNN 1108
Query: 420 ALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDE 477
AL V E++ + ++D++ + K EK+ R+L EL+ L E
Sbjct: 1109 ALKV------VRELQAQIAELQEDFESEKASRNKA------EKQKRDLSEELEALKTE 1154
Score = 42.7 bits (99), Expect = 8e-04
Identities = 76/359 (21%), Positives = 157/359 (43%), Gaps = 76/359 (21%)
Query: 169 VLDKEIIQLSDYLK-EALQRELVL--KQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGK 225
+L K++ +L L+ E QR L + K+KM I L I+A++ + D++ +
Sbjct: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKA------RDEVIKQ 1646
Query: 226 LRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQ---KAKESLQKVLE---EKMNAEQ 279
LR L+ Q MK E+E+ + S ++ ++KES +K+ E + ++
Sbjct: 1647 LRKLQAQ------------MKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 280 QLQSTQRSLALAEQKCEEWRSQY-------EALKEDWRTLGTQHRELESQLHVLQSKLQG 332
+L S++R+ AEQ+ +E + AL ++ R L + +LE +L QS ++
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 333 ADSR----DLQMN-----------------QALRFLENEHQQLQAKIECLQGDRDLCSLD 371
+ R LQ++ A + LE ++++L+AK++ L+G
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEG-------- 1806
Query: 372 TQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPN 431
+ +A L ++ QL+ L+ ++ + KL+ + ++ L K
Sbjct: 1807 -----AVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKL-----KEIFM 1856
Query: 432 EVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCRE 490
+VE E ++ ++Q++K +++ +++ E E + R+L E
Sbjct: 1857 QVEDERRHADQ---YKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATE 1912
Score = 35.8 bits (81), Expect = 0.100
Identities = 42/234 (17%), Positives = 105/234 (44%), Gaps = 20/234 (8%)
Query: 268 QKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQ 327
+K +K L+ QR+ A A K W+ W + T+ + L Q+ +
Sbjct: 803 RKAFAKKQQQLSALKVLQRNCA-AYLKLRHWQ---------WWRVFTKVKPL-LQVTRQE 851
Query: 328 SKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKL 387
+LQ D L++ + +E E ++++ K + L ++++ + Q + +E +
Sbjct: 852 EELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911
Query: 388 TLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLR 447
L + Q+L+ +L + +++E+E +++Q L K ++ +++ R
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEE----ERNQILQN-EKKKMQAHIQDLEEQLDEEEGAR 966
Query: 448 DQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLR----KLQHCREELNQSQQ 497
+LQ + + +AK K+ E L++ + +++ + ++ C +L + ++
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 63.9 bits (154), Expect = 3e-10
Identities = 68/271 (25%), Positives = 120/271 (44%), Gaps = 45/271 (16%)
Query: 262 KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELES 321
K K LQ V +E + + Q Q +LA+AE + + Q + KE L ++H+E+ES
Sbjct: 184 KLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 243
Query: 322 QLHVLQSKLQGADS------------RDLQMNQ--ALRFLENEHQQLQAKIECLQGDRDL 367
+L + +LQ S + QM Q ++ LE+E ++ ++ L+ +R
Sbjct: 244 ELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAF 303
Query: 368 CSLDTQDLQDQLKRSEAE---KLTLVTRVQQ---------LQGLLQNQSLQLQEQ----- 410
TQ L ++ K+ E K+ R QQ LQ L+ + QL E
Sbjct: 304 LRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTL 363
Query: 411 EKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSE 470
E+L K A+ + ++ K+ DL +Q K L L E++ +L E
Sbjct: 364 EELAWKHHMAIEAVHSNAIRDK-------KKLQMDLEEQHNKDKLNL---EEDKNQLQQE 413
Query: 471 LDN----LSDEYLSCLRKLQHCREELNQSQQ 497
L+N L D+ + +++ H ++ + +S+Q
Sbjct: 414 LENLKEVLEDKLNTANQEIGHLQDMVRKSEQ 444
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 41/255 (16%)
Query: 250 LEMEDQKNSYEQKAKESLQKVLEEKMN-AEQQLQSTQRSLALAEQKCEEWRSQYEALKED 308
L +E+ KN +Q+ E+L++VLE+K+N A Q++ Q + +EQ +L++
Sbjct: 401 LNLEEDKNQLQQEL-ENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQD- 458
Query: 309 WRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDR--- 365
L+++L + + L+ +++D +N LE E QQ + I ++ +
Sbjct: 459 ------SQERLQNELDLTKDSLK--ETKDALLNVEGE-LEQERQQHEETIAAMKEEEKLK 509
Query: 366 -DLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQG--LLQNQSLQLQEQEKLLTKKDQALP 422
D + D + + R E KL R+Q + +Q LQL+++E K+ A
Sbjct: 510 VDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDRE-----KNAARD 564
Query: 423 VWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCL 482
W K + D L + +L Q E + + + L L ++
Sbjct: 565 SWQKK------------------VEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQER 606
Query: 483 RKLQHCREELNQSQQ 497
++L EEL + Q
Sbjct: 607 QRLTQELEELEEQHQ 621
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/264 (20%), Positives = 110/264 (41%), Gaps = 24/264 (9%)
Query: 249 LLEMEDQ-----KNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYE 303
LL+++D+ ++S+++K ++ L ++ K N E QL +Q SL +Q ++ + +
Sbjct: 551 LLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSL---QQLQAQFTQERQ 607
Query: 304 ALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQ---------L 354
L ++ L QH++ L ++ + + + + + R LEN QQ
Sbjct: 608 RLTQELEELEEQHQQRHKSLK--EAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLK 665
Query: 355 QAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLL 414
A E ++G R + Q L+ +L+ L + Q L+ ++L
Sbjct: 666 DAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELA 725
Query: 415 TKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNL 474
K + +S + DL+++L+ + + +KE + LH + L
Sbjct: 726 AAKMEL-----ERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISAL 780
Query: 475 SDEYLSCLRKLQHCREELNQSQQL 498
+ E +++ R E NQ +L
Sbjct: 781 TKELEFKGKEILRIRSESNQQIRL 804
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 63.9 bits (154), Expect = 3e-10
Identities = 68/271 (25%), Positives = 120/271 (44%), Gaps = 45/271 (16%)
Query: 262 KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELES 321
K K LQ V +E + + Q Q +LA+AE + + Q + KE L ++H+E+ES
Sbjct: 304 KLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 363
Query: 322 QLHVLQSKLQGADS------------RDLQMNQ--ALRFLENEHQQLQAKIECLQGDRDL 367
+L + +LQ S + QM Q ++ LE+E ++ ++ L+ +R
Sbjct: 364 ELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAF 423
Query: 368 CSLDTQDLQDQLKRSEAE---KLTLVTRVQQ---------LQGLLQNQSLQLQEQ----- 410
TQ L ++ K+ E K+ R QQ LQ L+ + QL E
Sbjct: 424 LRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTL 483
Query: 411 EKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSE 470
E+L K A+ + ++ K+ DL +Q K L L E++ +L E
Sbjct: 484 EELAWKHHMAIEAVHSNAIRDK-------KKLQMDLEEQHNKDKLNL---EEDKNQLQQE 533
Query: 471 LDN----LSDEYLSCLRKLQHCREELNQSQQ 497
L+N L D+ + +++ H ++ + +S+Q
Sbjct: 534 LENLKEVLEDKLNTANQEIGHLQDMVRKSEQ 564
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 41/255 (16%)
Query: 250 LEMEDQKNSYEQKAKESLQKVLEEKMN-AEQQLQSTQRSLALAEQKCEEWRSQYEALKED 308
L +E+ KN +Q+ E+L++VLE+K+N A Q++ Q + +EQ +L++
Sbjct: 521 LNLEEDKNQLQQEL-ENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQD- 578
Query: 309 WRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDR--- 365
L+++L + + L+ +++D +N LE E QQ + I ++ +
Sbjct: 579 ------SQERLQNELDLTKDSLK--ETKDALLNVEGE-LEQERQQHEETIAAMKEEEKLK 629
Query: 366 -DLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQG--LLQNQSLQLQEQEKLLTKKDQALP 422
D + D + + R E KL R+Q + +Q LQL+++E K+ A
Sbjct: 630 VDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDRE-----KNAARD 684
Query: 423 VWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCL 482
W K + D L + +L Q E + + + L L ++
Sbjct: 685 SWQKK------------------VEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQER 726
Query: 483 RKLQHCREELNQSQQ 497
++L EEL + Q
Sbjct: 727 QRLTQELEELEEQHQ 741
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/264 (20%), Positives = 110/264 (41%), Gaps = 24/264 (9%)
Query: 249 LLEMEDQ-----KNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYE 303
LL+++D+ ++S+++K ++ L ++ K N E QL +Q SL +Q ++ + +
Sbjct: 671 LLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSL---QQLQAQFTQERQ 727
Query: 304 ALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQ---------L 354
L ++ L QH++ L ++ + + + + + R LEN QQ
Sbjct: 728 RLTQELEELEEQHQQRHKSLK--EAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLK 785
Query: 355 QAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLL 414
A E ++G R + Q L+ +L+ L + Q L+ ++L
Sbjct: 786 DAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELA 845
Query: 415 TKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNL 474
K + +S + DL+++L+ + + +KE + LH + L
Sbjct: 846 AAKMEL-----ERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISAL 900
Query: 475 SDEYLSCLRKLQHCREELNQSQQL 498
+ E +++ R E NQ +L
Sbjct: 901 TKELEFKGKEILRIRSESNQQIRL 924
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 63.9 bits (154), Expect = 3e-10
Identities = 87/424 (20%), Positives = 176/424 (41%), Gaps = 61/424 (14%)
Query: 120 DHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKN--DASQQTNYGVAVLDKEIIQL 177
+ L ++ G ++ +K+ ++ K + I+ + Q+ N + V + +++
Sbjct: 1046 EKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEG 1105
Query: 178 SDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNED---------KLKGKLRS 228
L E Q K K+ L+ +L T Q + S +L +D KL+ L+
Sbjct: 1106 KRALSELTQGVTCYKAKIKELETILET--QKVECSHSAKLEQDILEKESIILKLERNLKE 1163
Query: 229 LENQLYTCTQKYSPWGMKKVLLEME-DQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRS 287
+ L + +K++ L+ E Q + Q K LQ EE+ Q+ + +
Sbjct: 1164 FQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEE 1223
Query: 288 LALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFL 347
L+ + + + ++ + +ED+ L+ KL A + Q+ + + +
Sbjct: 1224 LSASSARTQNLKADLQRKEEDYAD--------------LKEKLTDAKKQIKQVQKEVSVM 1269
Query: 348 ENEHQQLQAKIECLQGDRDLCSLD-------TQDLQDQLKRSEAEKL-----TLVTRVQQ 395
+E + L+ KI L+ ++ CS + Q L++QL + E+ +
Sbjct: 1270 RDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNV 1329
Query: 396 LQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTL 455
+ ++++ + L+EQE+ ++DQ L ++ EVE T EK + + L+ K
Sbjct: 1330 KEKIIEDMRMTLEEQEQTQVEQDQVL-----EAKLEEVERLATELEKWKEKCNDLETKNN 1384
Query: 456 QLQAKEKECR-ELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVV 514
Q KE E ++ +L NL DE LQ ++ N ++ +WL M++
Sbjct: 1385 QRSNKEHENNTDVLGKLTNLQDE-------LQESEQKYNADRK--------KWLEEKMML 1429
Query: 515 IAAA 518
I A
Sbjct: 1430 ITQA 1433
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/316 (19%), Positives = 137/316 (43%), Gaps = 47/316 (14%)
Query: 185 LQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLE-NQLYTCTQKYSPW 243
+ +L+ + + + +D S + + +L +D+ K S+ + T QK S
Sbjct: 767 INNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSE- 825
Query: 244 GMKKVLLEMED----QKNSYEQKA-----KESLQKVLEEKMNAEQQLQSTQRSLALAEQK 294
++ + E+ED Q+N+ +A + L+ EEK +Q+ Q+ L+L+E+K
Sbjct: 826 EVRPNIAEIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKK 885
Query: 295 CEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQ----ALRFLENE 350
L ++ + + + + ++LHV +SK Q + + ++++ A R + N
Sbjct: 886 -------NLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNN 938
Query: 351 HQQLQA------KIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQS 404
Q++ ++ L + ++D +L+D SE + L N
Sbjct: 939 VSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN-------------LPNTQ 985
Query: 405 LQLQEQEKLLTKKDQALPVWSP---KSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKE 461
L L + L++K+ + + P SF + +E E+ ++ KK+ Q++ E
Sbjct: 986 LDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIW---EECKEIVKASSKKSHQIEELE 1042
Query: 462 KECRELHSELDNLSDE 477
++ +L +E+ DE
Sbjct: 1043 QQIEKLQAEVKGYKDE 1058
Score = 33.5 bits (75), Expect = 0.50
Identities = 46/234 (19%), Positives = 99/234 (42%), Gaps = 27/234 (11%)
Query: 159 ASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLN 218
A + N +++ + L + + ++++ VL+ K+ ++ L + L WK + N
Sbjct: 1323 ACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATEL-----EKWKEKCN 1377
Query: 219 EDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAE 278
+ + K RS + + + + L ++D+ EQK +K LEEKM
Sbjct: 1378 DLETKNNQRSNK-------EHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLI 1430
Query: 279 QQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLH-----------VLQ 327
Q + + +K E R ++ + + L Q E +S L L+
Sbjct: 1431 TQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALE 1490
Query: 328 SKLQGADSRDLQMN---QALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQ 378
+L+ S ++Q + + L+ + +E +++ +I ++ R + S D LQ +
Sbjct: 1491 IQLKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKR-ISSADPDKLQTE 1543
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 63.2 bits (152), Expect = 6e-10
Identities = 86/397 (21%), Positives = 174/397 (43%), Gaps = 69/397 (17%)
Query: 169 VLDKEIIQLSDYLKEALQRELVL-----KQKMVILQDLLSTLIQASDSSWKGQLNEDKLK 223
+L KE+ ++ KEALQ +L+ ++ + Q+LL + + S + K +++ +K K
Sbjct: 842 LLRKELEEIQSE-KEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEK 900
Query: 224 GKLRSLENQLYTCTQKYSPWGMKKVLL--------------------EMEDQKNSYEQKA 263
++ EN QK +++L E+E++ + E++
Sbjct: 901 CFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKEC 960
Query: 264 KESLQKVLEEKM---NAEQQLQSTQRSLALAEQKCEEWRSQYEALK----------EDWR 310
KE +K+ + K+ A+++L S+++ +++ E RS+ + L E ++
Sbjct: 961 KEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYK 1020
Query: 311 TLGTQHRELESQLHVLQSKLQGADSRDLQMNQALR-------FLENEHQQLQAKIECLQG 363
L ++ + QL V + + + R + + LR + ++++ L A+IE LQ
Sbjct: 1021 NLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQS 1080
Query: 364 DRDLCSLDTQDLQDQL----KRSEAEKL----------TLVTRVQQLQGLLQNQSLQLQE 409
+ L + ++Q K EAEKL T V +++LQ LQ + QLQ+
Sbjct: 1081 NAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQK 1140
Query: 410 --QEKLLTKKD------QALPVWSPKSFPNEVEPEGTGK-EKDWDLRDQLQKKTLQLQAK 460
QE L KKD + + + E+ + T K K DL +++ + + +
Sbjct: 1141 TMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL 1200
Query: 461 EKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
++E L S + ++ + L ++EL S+Q
Sbjct: 1201 QEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQ 1237
Score = 50.4 bits (119), Expect = 4e-06
Identities = 76/325 (23%), Positives = 142/325 (43%), Gaps = 55/325 (16%)
Query: 180 YLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQK 239
YL QR+ +LK+ L+ +++L + D +KLK ++N C ++
Sbjct: 571 YLLSLSQRDTMLKE----LEGKINSLTEEKDDFI------NKLKNSHEEMDNFHKKCERE 620
Query: 240 YSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
++++LE+ + Q E QKV E E+ L+ ++ +QK E+
Sbjct: 621 ------ERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQN----DQKLEKLM 670
Query: 300 SQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQ--MNQALRFLENEH-QQLQA 356
Q + L ED L + + L + + L S+ + SRDL+ ++Q + EH QL+
Sbjct: 671 VQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQL-SRDLEVFLSQKEDVILKEHITQLEK 729
Query: 357 KIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQE--QEKLL 414
K++ + ++D +L L+ + +KL + T QL G L+ ++ E +EK +
Sbjct: 730 KLQLMVEEQD-------NLNKLLENEQVQKLFVKT---QLYGFLKEMGSEVSEDSEEKDV 779
Query: 415 TKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEK--------ECRE 466
QA+ E E+ +L Q +K L+L+ + K +C E
Sbjct: 780 VNVLQAVG-----------ESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEE 828
Query: 467 LHSELDNLSDEYLSCLRKLQHCREE 491
L S L + E + ++L+ + E
Sbjct: 829 LKSLLRDYEQEKVLLRKELEEIQSE 853
Score = 50.4 bits (119), Expect = 4e-06
Identities = 89/366 (24%), Positives = 150/366 (40%), Gaps = 56/366 (15%)
Query: 170 LDKEIIQLSDYLKEALQR--ELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLR 227
L E QLS L+ L + +++LK+ + L+ L +++ D+ K NE K
Sbjct: 697 LSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQK---- 752
Query: 228 SLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYE-----QKAKESLQKVLEEKMNAEQQLQ 282
L+ TQ Y +K++ E+ + + Q ESL K+ EEK N Q
Sbjct: 753 -----LFVKTQLYG--FLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLA--FQ 803
Query: 283 STQRSLALAEQ-KC--EEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQ 339
++ L L ++ KC EE Q E LK R + L +L +QS+ + S L+
Sbjct: 804 RDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLE 863
Query: 340 MNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGL 399
M A E+Q L ++E + +Q +E EK + + L+ L
Sbjct: 864 MKNANEKTRLENQNLLIQVEEV----------SQTCSKSEIHNEKEK-CFIKEHENLKPL 912
Query: 400 LQNQSLQLQEQEKLLTKKDQAL-------PVWSPKSFPNEVEP-EGTGKEKDWDL----- 446
L+ + L+ + E +L K A P+ S K ++E E KEK+ +
Sbjct: 913 LEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKL 972
Query: 447 -----RDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREEL----NQSQQ 497
+ +L + Q ++E L SE D LS ++ + + L QS+Q
Sbjct: 973 VAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQ 1032
Query: 498 LPPRRQ 503
L ++
Sbjct: 1033 LDVEKE 1038
Score = 48.9 bits (115), Expect = 1e-05
Identities = 72/339 (21%), Positives = 143/339 (42%), Gaps = 54/339 (15%)
Query: 161 QQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDL-LSTLIQASDSSWKGQLNE 219
Q+ + V+++++ L D LKE + +LK ++ + +L L + A +
Sbjct: 321 QENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHER 380
Query: 220 DKLKGKLRSL-----ENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEK 274
+ L+ K+ L E K G+ K +Q N Q KE QK + E
Sbjct: 381 EDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISE- 439
Query: 275 MNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGAD 334
+N E L +++ + + + Q E L+++ + + L + +LQ++L +
Sbjct: 440 LN-ETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESA 498
Query: 335 SRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQ 394
+ Q ++++ Q QA D +LQ +L+ + EK L+ V
Sbjct: 499 GKISQEFESMK-------QQQAS-------------DVHELQQKLRTAFTEKDALLETVN 538
Query: 395 QLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKT 454
+LQG E EKLL+++ E+ PE K +L+++
Sbjct: 539 RLQG----------ENEKLLSQQ--------------ELVPELENTIK--NLQEKNGVYL 572
Query: 455 LQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELN 493
L L ++ +EL ++++L++E + KL++ EE++
Sbjct: 573 LSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMD 611
Score = 44.3 bits (103), Expect = 3e-04
Identities = 47/228 (20%), Positives = 96/228 (42%), Gaps = 32/228 (14%)
Query: 192 KQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLE 251
K+ + + Q++ ++ + D+ + + + ++ +L+N+L KYS
Sbjct: 97 KENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYS---------- 146
Query: 252 MEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRT 311
ED+ N LQK LEE MN + +L + +E ++ + + E ++ +
Sbjct: 147 -EDKAN---------LQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGF-- 194
Query: 312 LGTQHRELESQLHVLQSKLQG-ADSRDLQMNQALRFLENEHQQLQAKIECLQGD-RDLCS 369
E Q+ LQ +L D + + Q +E Q Q I LQ + L +
Sbjct: 195 --------EEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKA 246
Query: 370 LDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKK 417
+ +++++ + + EA + +L L +N Q + EK + KK
Sbjct: 247 IHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKK 294
Score = 43.1 bits (100), Expect = 6e-04
Identities = 70/341 (20%), Positives = 145/341 (42%), Gaps = 42/341 (12%)
Query: 168 AVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLR 227
A++DKE+ E LQ+E +K+ + +L +Q K QL + + +L
Sbjct: 1097 AMVDKELEA------EKLQKEQKIKEHATTVNELEELQVQLQKE--KKQLQKTMQELELV 1148
Query: 228 SLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRS 287
+ Q T ++++ E+ +QK + + E L++ ++ + ++ LQ S
Sbjct: 1149 KKDAQ-QTTLMNMEIADYERLMKEL-NQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITS 1206
Query: 288 LALAEQKCEEWRSQYEAL-----KE--DWRTLGTQHRELESQLH-VLQSKLQGADSRDLQ 339
L + Q+ EE ++ + L KE D + T H L++ L L++ Q + +Q
Sbjct: 1207 LQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQ 1266
Query: 340 MNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGL 399
+ + H+ L+ E Q LQ++ + ++AE+ T+ +
Sbjct: 1267 LAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTS-------- 1318
Query: 400 LQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDW------DLRDQLQKK 453
+ +S +++ L +K++++ ++ E EG +E++ L+ +LQ
Sbjct: 1319 -EFESYKVRVHNVLKQQKNKSM---------SQAETEGAKQEREHLEMLIDQLKIKLQDS 1368
Query: 454 TLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQ 494
LQ E + L SE D L + + L++ EL +
Sbjct: 1369 QNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELRE 1409
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 62.4 bits (150), Expect = 1e-09
Identities = 101/456 (22%), Positives = 176/456 (38%), Gaps = 84/456 (18%)
Query: 48 TLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQ 107
T+ +++E+L+ RL+Q R+ LE + Q +A EQ Q
Sbjct: 781 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQ-------------------Q 821
Query: 108 HPPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGV 167
P L + L+ + L ++ +++ + + E + +A + + G+
Sbjct: 822 LPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGL 881
Query: 168 AV----LDKEIIQLSDYL------KEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQL 217
AV ++E LS+ KEAL+ L Q+ + + ++A + L
Sbjct: 882 AVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL--L 939
Query: 218 NEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNA 277
++ L G+L L Q+ +K S L+ E Q +E+ + E++
Sbjct: 940 AKETLTGELAGLRQQIIATQEKAS--------LDKELMAQKLVQAEREAQASLREQRAAH 991
Query: 278 EQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRD 337
E+ LQ QR A WR L + +L+SQL Q +L
Sbjct: 992 EEDLQRLQREKEAA-----------------WRELEAERAQLQSQLQREQEEL------- 1027
Query: 338 LQMNQALRFLENEHQQLQAKIECLQGDRDL-CSLDTQDLQDQLKRSEAEKLTLVTRVQQL 396
L LE E ++L +I LQ +RD L + Q L E+EK L ++
Sbjct: 1028 ------LARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGT 1081
Query: 397 QGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQ 456
+ L SL+++ Q K+D +S N + E LRD ++
Sbjct: 1082 RHSLATISLEMERQ-----KRDAQSRQEQDRSTVNALTSE---------LRDLRAQREEA 1127
Query: 457 LQAKEKECRELHSELDNLSDEYLSCLRKLQHCREEL 492
A +E R L + +L + SCLR+ + R +L
Sbjct: 1128 AAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQL 1163
Score = 58.9 bits (141), Expect = 1e-08
Identities = 86/366 (23%), Positives = 167/366 (45%), Gaps = 56/366 (15%)
Query: 168 AVLDKEIIQLSDYLKEA-LQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKL 226
+VL KE++++ + L A LQR+++ +K + + L +A + +L+ KL+ +
Sbjct: 676 SVLAKELVEVREALSRATLQRDMLQAEKAEVAE----ALTKAEAGRVELELSMTKLRAEE 731
Query: 227 RSLENQLYTCTQ-----KYSPWGMKKVLLEMEDQKNSYEQK----------AKESLQKVL 271
SL++ L + + +++ ++E++K++ + + A+E +++
Sbjct: 732 ASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLE 791
Query: 272 EEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQ 331
E ++ E Q + SL +AEQ EAL++ TL + +L+ QL L +L
Sbjct: 792 ELRLEQEVARQGLEGSLRVAEQ-------AQEALEQQLPTLRHERSQLQEQLAQLSRQLS 844
Query: 332 GADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTL-- 389
G R+ ++ QA R E Q+ +E +++ + + L QL +E E TL
Sbjct: 845 G---REQELEQARR----EAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSE 897
Query: 390 -VTRV----QQLQGLL---QNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEV-------- 433
TR+ + L+G L Q Q QL+ + + L + QAL + + ++ E+
Sbjct: 898 EATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQAL-LLAKETLTGELAGLRQQII 956
Query: 434 -EPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSE-LDNLSDEYLSCLRKLQHCREE 491
E +K+ + +L + + QA +E R H E L L E + R+L+ R +
Sbjct: 957 ATQEKASLDKEL-MAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQ 1015
Query: 492 LNQSQQ 497
L Q
Sbjct: 1016 LQSQLQ 1021
Score = 49.7 bits (117), Expect = 7e-06
Identities = 71/328 (21%), Positives = 128/328 (39%), Gaps = 52/328 (15%)
Query: 217 LNEDKLKGKLRSLENQLYTCTQKYSPW-----GMKKVLLEMEDQKNSYEQKAKESLQKVL 271
L+ + ++G LR +L + ++ + + L EME +++S +A++ LQK +
Sbjct: 1502 LDPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQ-LQKAV 1560
Query: 272 EEKMNAEQ----QLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQ 327
E A + +L Q LAL E+ + A + TL + ES+L Q
Sbjct: 1561 AESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQ 1620
Query: 328 SK---------------------LQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRD 366
K L ++SR +++ R LE E Q+ + + +
Sbjct: 1621 EKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQ 1680
Query: 367 LCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSP 426
LQ Q+ SE + TL V++L G L +++E E L K + L
Sbjct: 1681 ALQDRVDSLQRQVADSEVKAGTLQLTVERLNGAL----AKVEESEGALRDKVRGLTEALA 1736
Query: 427 KSFPN---------EVEPEGTGKEKDWDL--------RDQLQKKTLQLQAKEKECRELHS 469
+S + ++ T E D + R L + Q + ++ + L
Sbjct: 1737 QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRG 1796
Query: 470 ELDNLSDEYLSCLRKLQHCREELNQSQQ 497
E+ +L + + +LQ RE L Q Q+
Sbjct: 1797 EVADLELQRVEAEGQLQQLREVLRQRQE 1824
Score = 46.2 bits (108), Expect = 7e-05
Identities = 73/330 (22%), Positives = 142/330 (43%), Gaps = 39/330 (11%)
Query: 198 LQDLLSTLI-QASDSSWKG---QLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEME 253
LQD + +L Q +DS K QL ++L G L +E K G+ + L +
Sbjct: 1682 LQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVR--GLTEALAQSS 1739
Query: 254 DQKNSYEQKAKESLQKVL----EEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDW 309
NS K LQK L ++ +++L + +++L+ A ++ Q + L+ +
Sbjct: 1740 ASLNSTRDKNLH-LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEV 1798
Query: 310 RTLGTQHRELESQLH----VLQSKLQGA-----------DSRDL------QMNQALRFLE 348
L Q E E QL VL+ + +G D R L + +AL LE
Sbjct: 1799 ADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLE 1858
Query: 349 NEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQ 408
E ++++ L+ DR ++ + RS + + L +L L L+L
Sbjct: 1859 AEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELA 1918
Query: 409 EQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQK-KTLQLQAKEK-ECRE 466
E ++ + + + + V P ++E + +++ +L+ ++++ ++ Q Q + E RE
Sbjct: 1919 EAQRQIQQLEAQVVVLEQSHSPAQLEVD--AQQQQLELQQEVERLRSAQAQTERTLEARE 1976
Query: 467 -LHSELDNLSDEYLSCLRKLQHCREELNQS 495
H + +E +S L+ ++EL +S
Sbjct: 1977 RAHRQRVRGLEEQVSTLK--GQLQQELRRS 2004
Score = 42.0 bits (97), Expect = 0.001
Identities = 93/431 (21%), Positives = 157/431 (36%), Gaps = 94/431 (21%)
Query: 119 SDHLSSQAGGLPPQDTPIKKPPKHH---RGTQTKAEGPTIKNDASQQTNYGVAVLDKEII 175
+D + GL Q TP PP+ RG + GP+ S + L K +
Sbjct: 477 ADASNGSLRGLSGQRTP--SPPRRSSPGRGRSPR-RGPSPACSDSSTLALIHSALHKRQL 533
Query: 176 QLSDYLKEALQRELVLKQKMVILQDLLSTLI-QASDSSWKGQLNEDKLKGKLRSLENQLY 234
Q+ D ++ + QDLL TL Q SDS + + R+LE QL
Sbjct: 534 QVQD-----------MRGRYEASQDLLGTLRKQLSDS-----------ESERRALEEQLQ 571
Query: 235 TCTQKYSPWGMKKVLLEMEDQK----NSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLAL 290
K + E Q+ N + K +L L+ ++L+ + L
Sbjct: 572 RLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 631
Query: 291 AEQKCEEWRSQYEALKED--------WRTLGTQHRELES--------------------- 321
A+++ R + E +ED R L HR+LE
Sbjct: 632 AQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSR 691
Query: 322 ---QLHVLQSK-------LQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLD 371
Q +LQ++ L A++ +++ ++ L E LQ + L + + D
Sbjct: 692 ATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQD 751
Query: 372 TQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPN 431
DL + + E EK L R +Q + Q ++ +EQE+L +
Sbjct: 752 KLDLNRLVAQLEEEKSALQGRQRQAE---QEATVAREEQERL-------------EELRL 795
Query: 432 EVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREE 491
E E G E + +Q Q +A E++ L E L ++ R+L +E
Sbjct: 796 EQEVARQGLEGSLRVAEQAQ------EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQE 849
Query: 492 LNQSQQLPPRR 502
L Q+++ R+
Sbjct: 850 LEQARREAQRQ 860
Score = 38.1 bits (87), Expect = 0.020
Identities = 39/183 (21%), Positives = 84/183 (45%), Gaps = 12/183 (6%)
Query: 221 KLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQ 280
+L+ + R L Q +C ++ ++ L +ED ++ ++ E+ +K+ E + E Q
Sbjct: 1137 RLQEQARDLGKQRDSCLREAEE--LRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 1194
Query: 281 LQST---QRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRD 337
Q +RSL E + EAL+ L + ++ ES+ L+ + + +
Sbjct: 1195 RQEAGELRRSLG-------EGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKL 1247
Query: 338 LQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQ 397
+ +A + E +L+ ++ ++ R + Q+L+ Q+K ++E L + +LQ
Sbjct: 1248 ALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQ 1307
Query: 398 GLL 400
G L
Sbjct: 1308 GRL 1310
Score = 37.0 bits (84), Expect = 0.045
Identities = 50/225 (22%), Positives = 97/225 (43%), Gaps = 29/225 (12%)
Query: 266 SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHV 325
SL + EE +Q+L + LA + + +E +Y A+ E LE L +
Sbjct: 75 SLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSE----------RLEQALRL 124
Query: 326 LQSKLQGADSRDL--QMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQL-KRS 382
+L+ + R L Q + R L+ E + K++ Q + Q Q QL +R
Sbjct: 125 EPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQ--------EGQQRQAQLVQRL 176
Query: 383 EAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEK 442
+ + L R +L+ L +S +L++Q T+ Q L + E + + +
Sbjct: 177 QGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLES-ALIRLEEEQQRSASLAQV 235
Query: 443 DWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQH 487
+ LR+QL + QA ++ R+ +++++ C ++L+H
Sbjct: 236 NAMLREQLDQAGSANQALSEDIRK-------VTNDWTRCRKELEH 273
Score = 35.0 bits (79), Expect = 0.17
Identities = 57/264 (21%), Positives = 111/264 (42%), Gaps = 30/264 (11%)
Query: 175 IQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNED-KLKGKLRSLENQL 233
++L + ++ L+REL+ Q+ + + + + L E K + LR +L
Sbjct: 1163 LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEEL 1222
Query: 234 YTCTQKYSPWGMK-KVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAE 292
+ +K + K+ E ++QK + ++A+ ++ K E LQ +RS A
Sbjct: 1223 RSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTG---LQEVERSRLEAR 1279
Query: 293 QKCEEWRSQYEALKEDWRTLGTQHRELESQLHV-------LQSKLQGADSRDLQMNQALR 345
++ +E R Q + L + LG + EL+ +L + + + G R L+ +L
Sbjct: 1280 RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLE 1339
Query: 346 FLENEHQQLQAKIECLQGD------RDLCSLD------------TQDLQDQLKRSEAEKL 387
+ E Q Q K++ +G+ R L SL+ + L+ +L+ + AE
Sbjct: 1340 VMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAA 1399
Query: 388 TLVTRVQQLQGLLQNQSLQLQEQE 411
L R+ +G Q +L E
Sbjct: 1400 ELGLRLSAAEGRAQGLEAELARVE 1423
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 62.0 bits (149), Expect = 1e-09
Identities = 80/330 (24%), Positives = 144/330 (43%), Gaps = 39/330 (11%)
Query: 172 KEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLEN 231
+E+ + + L + Q L QK+ LQ STL + D + + L E
Sbjct: 207 RELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQ 266
Query: 232 QLYTCTQKYSPWGMKKVLLEMEDQKN--SYEQKAKESLQKVLEEKMNAEQQLQSTQRSLA 289
+L Q+ S ++KV E +++++ ++ Q+ SL+K LE+ ++ E+ +Q +
Sbjct: 267 ELQALIQQLS-IDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHVQELLKEKT 325
Query: 290 LAEQKCEEWRSQYEALKEDW----RTLGTQHRELESQLHVLQSKLQ------GADSRDLQ 339
LAEQ E+ R Q A + TL T+ RELE L + +LQ A +Q
Sbjct: 326 LAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQQSKGIVAAQETQIQ 385
Query: 340 ------------MNQAL----RFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSE 383
QAL +FLE Q L+A+I L+ R + D + +++ E
Sbjct: 386 ELAAANQESSHVQQQALALEQQFLERT-QALEAQIVALERTR---AADQTTAEQGMRQLE 441
Query: 384 AEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKD-----QALPVWSPKSFPNEVEPEGT 438
E L + + LQN +L++ ++ ++++ A + + E + +
Sbjct: 442 QENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQREEFQQQAA 501
Query: 439 GKEKDWDLRDQ-LQKKTLQLQAKEKECREL 467
D ++Q L++KT L KE+E +L
Sbjct: 502 NLTAIIDEKEQNLREKTEVLLQKEQEILQL 531
Score = 57.4 bits (137), Expect = 3e-08
Identities = 70/284 (24%), Positives = 126/284 (44%), Gaps = 38/284 (13%)
Query: 202 LSTLIQASDSSWK---GQLNEDK--LKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQK 256
L+ + D W QL ++K L +L+ ++NQ Q+ + + E K
Sbjct: 124 LALALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSK 183
Query: 257 NSYEQ-KAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQ 315
+ K +ESL K+ +E ++L TQ L + Q + + E L+ + TL Q
Sbjct: 184 IKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQ 243
Query: 316 HRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDL 375
HV+ SK GA+S+ + LE + Q+LQA I+ L D + +TQ+
Sbjct: 244 RD------HVIASKT-GAESK-------ITALEQKEQELQALIQQLSIDLQKVTAETQEK 289
Query: 376 QDQLKRSEAEKLTLVTRVQQ-------LQGLLQ-----NQSLQLQEQEKLLTKKDQALPV 423
+D + + + +L R++Q +Q LL+ Q+L+ Q+ L + QA +
Sbjct: 290 EDVITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAI 349
Query: 424 WSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECREL 467
+ ++ E+E E +QLQ+ + A+E + +EL
Sbjct: 350 NTLETRVRELEQTLQASE------EQLQQSKGIVAAQETQIQEL 387
Score = 39.3 bits (90), Expect = 0.009
Identities = 73/318 (22%), Positives = 130/318 (40%), Gaps = 41/318 (12%)
Query: 172 KEIIQLSDYLKEALQREL-VLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLE 230
+E+ Q +E LQ+ ++ + +Q+L + ++S + E + + ++LE
Sbjct: 357 RELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALE 416
Query: 231 NQLYT------CTQKYSPWGMKKVLLE---MEDQKNSYEQKAKESLQK-VLEEKMNAEQQ 280
Q+ Q + GM+++ E +++ +N YE+ SLQ E K E+
Sbjct: 417 AQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYER----SLQNHQFELKKLKEEW 472
Query: 281 LQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQM 340
Q S+A+A Q EE R Q E ++ L E E L L + LQ+
Sbjct: 473 SQREIVSVAMA-QALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQL 531
Query: 341 NQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLL 400
+ + QLQA++E L+ LK EA + + +L+G L
Sbjct: 532 ERGHNSALLQIHQLQAELEALR---------------TLKAEEAAVVAEQEDLLRLRGPL 576
Query: 401 QNQSLQLQEQEKLLTKKDQALPVW-------SPKSFPNEVEPEGTGKEKDWDLRDQLQKK 453
Q ++L + E +T + PV+ +P ++ KEK DL QL +K
Sbjct: 577 QAEALSVNESH--VTSRAMQDPVFQLPTAGRTPNGEVGAMDLTQLQKEKQ-DLEQQLLEK 633
Query: 454 TLQLQAKEKECRELHSEL 471
++ ++ EL L
Sbjct: 634 NKTIKQMQQRMLELRKTL 651
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/264 (23%), Positives = 124/264 (46%), Gaps = 28/264 (10%)
Query: 247 KVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQK----CEEWRSQY 302
K LL++ Q + +A+E LQKV E + + +++ Q +A E++ E+ R++
Sbjct: 867 KPLLQVTRQDEVLQARAQE-LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA 925
Query: 303 EALKEDWRTLG---TQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
E E T G + +ELE + L++++ + QM + L+ Q+L+A +E
Sbjct: 926 ELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE 985
Query: 360 CLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
+G R L+ + ++K+ E + L LL++Q+ +L ++ KLL +
Sbjct: 986 AEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLSKERKLL---ED 1031
Query: 420 ALPVWSPKSFPNEVEPEGTGKEK------DWDLRDQLQKKTLQLQAKEKECRELHSELDN 473
L +S ++ E + + K + D+ D+L+K+ Q EK R L E
Sbjct: 1032 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1091
Query: 474 LSDEYLSCLRKLQHCREELNQSQQ 497
L ++ + ++ + R +L + ++
Sbjct: 1092 LQEQMVEQQQRAEELRAQLGRKEE 1115
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/304 (20%), Positives = 132/304 (43%), Gaps = 36/304 (11%)
Query: 221 KLKGKLRSLENQLYTCTQ---------KYSPWGMKKVLLEMEDQKNSYEQ------KAKE 265
KL+G+L L+ Q+ + Q + MK++ E+E+ + S E+ ++++
Sbjct: 1646 KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1705
Query: 266 SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHV 325
L+ + E + +++L ++ R+ A+Q +E + + + R+LE +L
Sbjct: 1706 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1765
Query: 326 LQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC-------LQGDRDLCSLDTQDLQDQ 378
L+ +L+ S +N R L + + L ++ + R Q+L+ +
Sbjct: 1766 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGR 1825
Query: 379 LKRSEA-----EKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEV 433
L +A K+T+ +L + L+ + +E++L+ K K +V
Sbjct: 1826 LGEEDAGARARHKMTIAALESKLAQA--EEQLEQETRERILSGKLVRRAEKRLKEVVLQV 1883
Query: 434 EPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELN 493
E E ++ LRDQL+K L+++ +++ E E + R+LQ E++
Sbjct: 1884 EEERRVADQ---LRDQLEKGNLRVKQLKRQLEEAEEEASRAQ----AGRRRLQRELEDVT 1936
Query: 494 QSQQ 497
+S +
Sbjct: 1937 ESAE 1940
Score = 46.6 bits (109), Expect = 6e-05
Identities = 57/271 (21%), Positives = 113/271 (41%), Gaps = 54/271 (19%)
Query: 246 KKVLLEMEDQKNSYEQKAKE------SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
K +L +++ E + +E SL + LEE+ A ++L+ R+L R
Sbjct: 1486 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL----------R 1535
Query: 300 SQYEALKEDWRTLGTQHRELE--------------SQLHVLQSKLQGADSRDLQMNQALR 345
++ EAL +G ELE +Q+ L+ +L A+ L++ ++
Sbjct: 1536 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1595
Query: 346 FLENEHQQ-LQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQS 404
L+ +H++ LQ + E + R + +D + + ++ V ++L+G L+
Sbjct: 1596 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELK 1655
Query: 405 LQL-------QEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKK---- 453
Q+ +E K L K + K EVE T +E+ + + +K+
Sbjct: 1656 AQMASAGQGKEEAVKQLRKMQAQM-----KELWREVEETRTSREEIFSQNRESEKRLKGL 1710
Query: 454 ---TLQLQ----AKEKECRELHSELDNLSDE 477
L+LQ A ++ R+ + D ++DE
Sbjct: 1711 EAEVLRLQEELAASDRARRQAQQDRDEMADE 1741
Score = 46.2 bits (108), Expect = 7e-05
Identities = 45/226 (19%), Positives = 111/226 (49%), Gaps = 20/226 (8%)
Query: 251 EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQK-----CEEWRSQY--- 302
+++ + + E++ ++ +++ + ++ +++ + QR+LA+A +K EE ++Q
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERK--QRTLAVAARKKLEGELEELKAQMASA 1661
Query: 303 -----EALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAK 357
EA+K+ R + Q +EL ++ ++ + S++ + + L+ LE E +LQ +
Sbjct: 1662 GQGKEEAVKQ-LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
Query: 358 IECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE---KLL 414
+ R D ++ D++ K ++ +QL+G L +L+E++ +LL
Sbjct: 1721 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1780
Query: 415 TKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK 460
+ + L + +S E+ E + K R QL+++ +L+ +
Sbjct: 1781 NDRYRKL-LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGR 1825
Score = 43.9 bits (102), Expect = 4e-04
Identities = 104/513 (20%), Positives = 206/513 (40%), Gaps = 53/513 (10%)
Query: 7 RPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTL-RIQQREQLQRARLQQF 65
+P + R E +A+ + Q+++E ++ + R+VG+ R+ Q E+ +RARL +
Sbjct: 867 KPLLQVTRQDEVLQARAQELQKVQELQQ-----QSAREVGELQGRVAQLEE-ERARLAEQ 920
Query: 66 FRRRN---LELEE-KGK-AQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGI---CRD 117
R E EE +G+ A Q E S +V G E + ++
Sbjct: 921 LRAEAELCAEAEETRGRLAARKQELELVVSELEARV-GEEEECSRQMQTEKKRLQQHIQE 979
Query: 118 LSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQL 177
L HL ++ G Q ++K + + + E + D + + + +L+ + +
Sbjct: 980 LEAHLEAEEGAR--QKLQLEKVTTEAKMKKFE-EDLLLLEDQNSKLSKERKLLEDRLAEF 1036
Query: 178 SDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLK----GKLRSLENQL 233
S E ++ L + + + ++ + KG+ +KLK G+ L+ Q+
Sbjct: 1037 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1096
Query: 234 YTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQS---TQRSLAL 290
Q+ E+ Q E++ + +L + +E Q L+S Q +LA
Sbjct: 1097 VEQQQRAE---------ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAE 1147
Query: 291 AEQKCEEWRSQYEALKEDWRTLGTQ----HRELESQLHVLQSKLQGADSRDLQMNQALRF 346
A++ E R ++ R LG + ELE L ++ + R+ ++ + +
Sbjct: 1148 AQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKT 1207
Query: 347 LENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS----EAEKLTLVTRVQQLQGLLQN 402
LE E + +A ++ L+ + + +Q +R E +L L V +L+ L +
Sbjct: 1208 LEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSS 1267
Query: 403 QSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPE-GTGKEKDWDLRDQLQKKTLQLQAKE 461
QE E+ + + L EV+ G G+ + ++LQ+ +L+
Sbjct: 1268 LQTARQEGEQRRRRLELQL---------QEVQGRAGDGERARAEAAEKLQRAQAELENVS 1318
Query: 462 KECRELHSELDNLSDEYLSCLRKLQHCREELNQ 494
E S+ LS E S +L +E L +
Sbjct: 1319 GALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1351
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/292 (18%), Positives = 118/292 (40%), Gaps = 37/292 (12%)
Query: 251 EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWR 310
E ++ + + L+ +L K + + + +R+ +AEQ + R+Q L+++
Sbjct: 1522 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1581
Query: 311 TLGTQHRELESQLHVLQSK----LQGAD----SRDLQMNQALRFLENE------------ 350
LE + L+++ LQG D R Q+ + LR E E
Sbjct: 1582 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1641
Query: 351 --HQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQ 408
++L+ ++E L+ ++ QL++ +A+ L V++ + + Q +
Sbjct: 1642 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1701
Query: 409 EQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTL----------QLQ 458
E EK L + + + ++ +++D ++ D++ L QL+
Sbjct: 1702 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRD-EMADEVANGNLSKAAILEEKRQLE 1760
Query: 459 AK----EKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGR 506
+ E+E E S + L+D Y L +++ EL+ + + + GR
Sbjct: 1761 GRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1812
Score = 39.7 bits (91), Expect = 0.007
Identities = 55/278 (19%), Positives = 103/278 (37%), Gaps = 16/278 (5%)
Query: 246 KKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEAL 305
KK L + + ++ + + + QK+ EK+ E +++ + L L E + + + + L
Sbjct: 970 KKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1029
Query: 306 KEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDR 365
++ +Q E E ++ L ++ M LR E Q+L+ L G+
Sbjct: 1030 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1089
Query: 366 DLCSLD-------TQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKD 418
++L+ QL R E E + R + G L+E + L +
Sbjct: 1090 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQ 1149
Query: 419 QALPVWSPKSFPNEVEPEGTGKEKD---WDLRDQLQKKTLQLQAKEKECRELHSELDNLS 475
+ L E + G+E + +L D L Q + + K +E+ L
Sbjct: 1150 EDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE 1209
Query: 476 DEYLSCLRKLQHCREELNQS------QQLPPRRQCGRW 507
+E +Q R+ Q+ Q RR G W
Sbjct: 1210 EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAW 1247
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/264 (23%), Positives = 124/264 (46%), Gaps = 28/264 (10%)
Query: 247 KVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQK----CEEWRSQY 302
K LL++ Q + +A+E LQKV E + + +++ Q +A E++ E+ R++
Sbjct: 859 KPLLQVTRQDEVLQARAQE-LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA 917
Query: 303 EALKEDWRTLG---TQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
E E T G + +ELE + L++++ + QM + L+ Q+L+A +E
Sbjct: 918 ELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE 977
Query: 360 CLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
+G R L+ + ++K+ E + L LL++Q+ +L ++ KLL +
Sbjct: 978 AEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLSKERKLL---ED 1023
Query: 420 ALPVWSPKSFPNEVEPEGTGKEK------DWDLRDQLQKKTLQLQAKEKECRELHSELDN 473
L +S ++ E + + K + D+ D+L+K+ Q EK R L E
Sbjct: 1024 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1083
Query: 474 LSDEYLSCLRKLQHCREELNQSQQ 497
L ++ + ++ + R +L + ++
Sbjct: 1084 LQEQMVEQQQRAEELRAQLGRKEE 1107
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/304 (20%), Positives = 132/304 (43%), Gaps = 36/304 (11%)
Query: 221 KLKGKLRSLENQLYTCTQ---------KYSPWGMKKVLLEMEDQKNSYEQ------KAKE 265
KL+G+L L+ Q+ + Q + MK++ E+E+ + S E+ ++++
Sbjct: 1638 KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1697
Query: 266 SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHV 325
L+ + E + +++L ++ R+ A+Q +E + + + R+LE +L
Sbjct: 1698 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1757
Query: 326 LQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC-------LQGDRDLCSLDTQDLQDQ 378
L+ +L+ S +N R L + + L ++ + R Q+L+ +
Sbjct: 1758 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGR 1817
Query: 379 LKRSEA-----EKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEV 433
L +A K+T+ +L + L+ + +E++L+ K K +V
Sbjct: 1818 LGEEDAGARARHKMTIAALESKLAQA--EEQLEQETRERILSGKLVRRAEKRLKEVVLQV 1875
Query: 434 EPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELN 493
E E ++ LRDQL+K L+++ +++ E E + R+LQ E++
Sbjct: 1876 EEERRVADQ---LRDQLEKGNLRVKQLKRQLEEAEEEASRAQ----AGRRRLQRELEDVT 1928
Query: 494 QSQQ 497
+S +
Sbjct: 1929 ESAE 1932
Score = 46.6 bits (109), Expect = 6e-05
Identities = 57/271 (21%), Positives = 113/271 (41%), Gaps = 54/271 (19%)
Query: 246 KKVLLEMEDQKNSYEQKAKE------SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
K +L +++ E + +E SL + LEE+ A ++L+ R+L R
Sbjct: 1478 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL----------R 1527
Query: 300 SQYEALKEDWRTLGTQHRELE--------------SQLHVLQSKLQGADSRDLQMNQALR 345
++ EAL +G ELE +Q+ L+ +L A+ L++ ++
Sbjct: 1528 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1587
Query: 346 FLENEHQQ-LQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQS 404
L+ +H++ LQ + E + R + +D + + ++ V ++L+G L+
Sbjct: 1588 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELK 1647
Query: 405 LQL-------QEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKK---- 453
Q+ +E K L K + K EVE T +E+ + + +K+
Sbjct: 1648 AQMASAGQGKEEAVKQLRKMQAQM-----KELWREVEETRTSREEIFSQNRESEKRLKGL 1702
Query: 454 ---TLQLQ----AKEKECRELHSELDNLSDE 477
L+LQ A ++ R+ + D ++DE
Sbjct: 1703 EAEVLRLQEELAASDRARRQAQQDRDEMADE 1733
Score = 46.2 bits (108), Expect = 7e-05
Identities = 45/226 (19%), Positives = 111/226 (49%), Gaps = 20/226 (8%)
Query: 251 EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQK-----CEEWRSQY--- 302
+++ + + E++ ++ +++ + ++ +++ + QR+LA+A +K EE ++Q
Sbjct: 1596 DLQGRDEAGEERRRQLAKQLRDAEVERDEERK--QRTLAVAARKKLEGELEELKAQMASA 1653
Query: 303 -----EALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAK 357
EA+K+ R + Q +EL ++ ++ + S++ + + L+ LE E +LQ +
Sbjct: 1654 GQGKEEAVKQ-LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712
Query: 358 IECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE---KLL 414
+ R D ++ D++ K ++ +QL+G L +L+E++ +LL
Sbjct: 1713 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1772
Query: 415 TKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK 460
+ + L + +S E+ E + K R QL+++ +L+ +
Sbjct: 1773 NDRYRKL-LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGR 1817
Score = 43.9 bits (102), Expect = 4e-04
Identities = 104/513 (20%), Positives = 206/513 (40%), Gaps = 53/513 (10%)
Query: 7 RPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTL-RIQQREQLQRARLQQF 65
+P + R E +A+ + Q+++E ++ + R+VG+ R+ Q E+ +RARL +
Sbjct: 859 KPLLQVTRQDEVLQARAQELQKVQELQQ-----QSAREVGELQGRVAQLEE-ERARLAEQ 912
Query: 66 FRRRN---LELEE-KGK-AQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGI---CRD 117
R E EE +G+ A Q E S +V G E + ++
Sbjct: 913 LRAEAELCAEAEETRGRLAARKQELELVVSELEARV-GEEEECSRQMQTEKKRLQQHIQE 971
Query: 118 LSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQL 177
L HL ++ G Q ++K + + + E + D + + + +L+ + +
Sbjct: 972 LEAHLEAEEGAR--QKLQLEKVTTEAKMKKFE-EDLLLLEDQNSKLSKERKLLEDRLAEF 1028
Query: 178 SDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLK----GKLRSLENQL 233
S E ++ L + + + ++ + KG+ +KLK G+ L+ Q+
Sbjct: 1029 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1088
Query: 234 YTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQS---TQRSLAL 290
Q+ E+ Q E++ + +L + +E Q L+S Q +LA
Sbjct: 1089 VEQQQRAE---------ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAE 1139
Query: 291 AEQKCEEWRSQYEALKEDWRTLGTQ----HRELESQLHVLQSKLQGADSRDLQMNQALRF 346
A++ E R ++ R LG + ELE L ++ + R+ ++ + +
Sbjct: 1140 AQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKT 1199
Query: 347 LENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS----EAEKLTLVTRVQQLQGLLQN 402
LE E + +A ++ L+ + + +Q +R E +L L V +L+ L +
Sbjct: 1200 LEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSS 1259
Query: 403 QSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPE-GTGKEKDWDLRDQLQKKTLQLQAKE 461
QE E+ + + L EV+ G G+ + ++LQ+ +L+
Sbjct: 1260 LQTARQEGEQRRRRLELQL---------QEVQGRAGDGERARAEAAEKLQRAQAELENVS 1310
Query: 462 KECRELHSELDNLSDEYLSCLRKLQHCREELNQ 494
E S+ LS E S +L +E L +
Sbjct: 1311 GALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1343
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/292 (18%), Positives = 118/292 (40%), Gaps = 37/292 (12%)
Query: 251 EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWR 310
E ++ + + L+ +L K + + + +R+ +AEQ + R+Q L+++
Sbjct: 1514 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1573
Query: 311 TLGTQHRELESQLHVLQSK----LQGAD----SRDLQMNQALRFLENE------------ 350
LE + L+++ LQG D R Q+ + LR E E
Sbjct: 1574 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1633
Query: 351 --HQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQ 408
++L+ ++E L+ ++ QL++ +A+ L V++ + + Q +
Sbjct: 1634 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1693
Query: 409 EQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTL----------QLQ 458
E EK L + + + ++ +++D ++ D++ L QL+
Sbjct: 1694 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRD-EMADEVANGNLSKAAILEEKRQLE 1752
Query: 459 AK----EKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGR 506
+ E+E E S + L+D Y L +++ EL+ + + + GR
Sbjct: 1753 GRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1804
Score = 39.7 bits (91), Expect = 0.007
Identities = 55/278 (19%), Positives = 103/278 (37%), Gaps = 16/278 (5%)
Query: 246 KKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEAL 305
KK L + + ++ + + + QK+ EK+ E +++ + L L E + + + + L
Sbjct: 962 KKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1021
Query: 306 KEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDR 365
++ +Q E E ++ L ++ M LR E Q+L+ L G+
Sbjct: 1022 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1081
Query: 366 DLCSLD-------TQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKD 418
++L+ QL R E E + R + G L+E + L +
Sbjct: 1082 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQ 1141
Query: 419 QALPVWSPKSFPNEVEPEGTGKEKD---WDLRDQLQKKTLQLQAKEKECRELHSELDNLS 475
+ L E + G+E + +L D L Q + + K +E+ L
Sbjct: 1142 EDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE 1201
Query: 476 DEYLSCLRKLQHCREELNQS------QQLPPRRQCGRW 507
+E +Q R+ Q+ Q RR G W
Sbjct: 1202 EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAW 1239
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/264 (23%), Positives = 124/264 (46%), Gaps = 28/264 (10%)
Query: 247 KVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQK----CEEWRSQY 302
K LL++ Q + +A+E LQKV E + + +++ Q +A E++ E+ R++
Sbjct: 900 KPLLQVTRQDEVLQARAQE-LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA 958
Query: 303 EALKEDWRTLG---TQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIE 359
E E T G + +ELE + L++++ + QM + L+ Q+L+A +E
Sbjct: 959 ELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE 1018
Query: 360 CLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQ 419
+G R L+ + ++K+ E + L LL++Q+ +L ++ KLL +
Sbjct: 1019 AEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLSKERKLL---ED 1064
Query: 420 ALPVWSPKSFPNEVEPEGTGKEK------DWDLRDQLQKKTLQLQAKEKECRELHSELDN 473
L +S ++ E + + K + D+ D+L+K+ Q EK R L E
Sbjct: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
Query: 474 LSDEYLSCLRKLQHCREELNQSQQ 497
L ++ + ++ + R +L + ++
Sbjct: 1125 LQEQMVEQQQRAEELRAQLGRKEE 1148
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/304 (20%), Positives = 132/304 (43%), Gaps = 36/304 (11%)
Query: 221 KLKGKLRSLENQLYTCTQ---------KYSPWGMKKVLLEMEDQKNSYEQ------KAKE 265
KL+G+L L+ Q+ + Q + MK++ E+E+ + S E+ ++++
Sbjct: 1679 KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1738
Query: 266 SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHV 325
L+ + E + +++L ++ R+ A+Q +E + + + R+LE +L
Sbjct: 1739 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1798
Query: 326 LQSKLQGADSRDLQMNQALRFLENEHQQLQAKIEC-------LQGDRDLCSLDTQDLQDQ 378
L+ +L+ S +N R L + + L ++ + R Q+L+ +
Sbjct: 1799 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGR 1858
Query: 379 LKRSEA-----EKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEV 433
L +A K+T+ +L + L+ + +E++L+ K K +V
Sbjct: 1859 LGEEDAGARARHKMTIAALESKLAQA--EEQLEQETRERILSGKLVRRAEKRLKEVVLQV 1916
Query: 434 EPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELN 493
E E ++ LRDQL+K L+++ +++ E E + R+LQ E++
Sbjct: 1917 EEERRVADQ---LRDQLEKGNLRVKQLKRQLEEAEEEASRAQ----AGRRRLQRELEDVT 1969
Query: 494 QSQQ 497
+S +
Sbjct: 1970 ESAE 1973
Score = 46.6 bits (109), Expect = 6e-05
Identities = 57/271 (21%), Positives = 113/271 (41%), Gaps = 54/271 (19%)
Query: 246 KKVLLEMEDQKNSYEQKAKE------SLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR 299
K +L +++ E + +E SL + LEE+ A ++L+ R+L R
Sbjct: 1519 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL----------R 1568
Query: 300 SQYEALKEDWRTLGTQHRELE--------------SQLHVLQSKLQGADSRDLQMNQALR 345
++ EAL +G ELE +Q+ L+ +L A+ L++ ++
Sbjct: 1569 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1628
Query: 346 FLENEHQQ-LQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQS 404
L+ +H++ LQ + E + R + +D + + ++ V ++L+G L+
Sbjct: 1629 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELK 1688
Query: 405 LQL-------QEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKK---- 453
Q+ +E K L K + K EVE T +E+ + + +K+
Sbjct: 1689 AQMASAGQGKEEAVKQLRKMQAQM-----KELWREVEETRTSREEIFSQNRESEKRLKGL 1743
Query: 454 ---TLQLQ----AKEKECRELHSELDNLSDE 477
L+LQ A ++ R+ + D ++DE
Sbjct: 1744 EAEVLRLQEELAASDRARRQAQQDRDEMADE 1774
Score = 46.2 bits (108), Expect = 7e-05
Identities = 45/226 (19%), Positives = 111/226 (49%), Gaps = 20/226 (8%)
Query: 251 EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQK-----CEEWRSQY--- 302
+++ + + E++ ++ +++ + ++ +++ + QR+LA+A +K EE ++Q
Sbjct: 1637 DLQGRDEAGEERRRQLAKQLRDAEVERDEERK--QRTLAVAARKKLEGELEELKAQMASA 1694
Query: 303 -----EALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAK 357
EA+K+ R + Q +EL ++ ++ + S++ + + L+ LE E +LQ +
Sbjct: 1695 GQGKEEAVKQ-LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753
Query: 358 IECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE---KLL 414
+ R D ++ D++ K ++ +QL+G L +L+E++ +LL
Sbjct: 1754 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1813
Query: 415 TKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAK 460
+ + L + +S E+ E + K R QL+++ +L+ +
Sbjct: 1814 NDRYRKL-LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGR 1858
Score = 43.9 bits (102), Expect = 4e-04
Identities = 104/513 (20%), Positives = 206/513 (40%), Gaps = 53/513 (10%)
Query: 7 RPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTL-RIQQREQLQRARLQQF 65
+P + R E +A+ + Q+++E ++ + R+VG+ R+ Q E+ +RARL +
Sbjct: 900 KPLLQVTRQDEVLQARAQELQKVQELQQ-----QSAREVGELQGRVAQLEE-ERARLAEQ 953
Query: 66 FRRRN---LELEE-KGK-AQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGI---CRD 117
R E EE +G+ A Q E S +V G E + ++
Sbjct: 954 LRAEAELCAEAEETRGRLAARKQELELVVSELEARV-GEEEECSRQMQTEKKRLQQHIQE 1012
Query: 118 LSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQL 177
L HL ++ G Q ++K + + + E + D + + + +L+ + +
Sbjct: 1013 LEAHLEAEEGAR--QKLQLEKVTTEAKMKKFE-EDLLLLEDQNSKLSKERKLLEDRLAEF 1069
Query: 178 SDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLK----GKLRSLENQL 233
S E ++ L + + + ++ + KG+ +KLK G+ L+ Q+
Sbjct: 1070 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1129
Query: 234 YTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQS---TQRSLAL 290
Q+ E+ Q E++ + +L + +E Q L+S Q +LA
Sbjct: 1130 VEQQQRAE---------ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAE 1180
Query: 291 AEQKCEEWRSQYEALKEDWRTLGTQ----HRELESQLHVLQSKLQGADSRDLQMNQALRF 346
A++ E R ++ R LG + ELE L ++ + R+ ++ + +
Sbjct: 1181 AQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKT 1240
Query: 347 LENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS----EAEKLTLVTRVQQLQGLLQN 402
LE E + +A ++ L+ + + +Q +R E +L L V +L+ L +
Sbjct: 1241 LEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSS 1300
Query: 403 QSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPE-GTGKEKDWDLRDQLQKKTLQLQAKE 461
QE E+ + + L EV+ G G+ + ++LQ+ +L+
Sbjct: 1301 LQTARQEGEQRRRRLELQL---------QEVQGRAGDGERARAEAAEKLQRAQAELENVS 1351
Query: 462 KECRELHSELDNLSDEYLSCLRKLQHCREELNQ 494
E S+ LS E S +L +E L +
Sbjct: 1352 GALNEAESKTIRLSKELSSTEAQLHDAQELLQE 1384
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/292 (18%), Positives = 118/292 (40%), Gaps = 37/292 (12%)
Query: 251 EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWR 310
E ++ + + L+ +L K + + + +R+ +AEQ + R+Q L+++
Sbjct: 1555 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1614
Query: 311 TLGTQHRELESQLHVLQSK----LQGAD----SRDLQMNQALRFLENE------------ 350
LE + L+++ LQG D R Q+ + LR E E
Sbjct: 1615 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1674
Query: 351 --HQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQ 408
++L+ ++E L+ ++ QL++ +A+ L V++ + + Q +
Sbjct: 1675 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1734
Query: 409 EQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTL----------QLQ 458
E EK L + + + ++ +++D ++ D++ L QL+
Sbjct: 1735 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRD-EMADEVANGNLSKAAILEEKRQLE 1793
Query: 459 AK----EKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGR 506
+ E+E E S + L+D Y L +++ EL+ + + + GR
Sbjct: 1794 GRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1845
Score = 39.7 bits (91), Expect = 0.007
Identities = 55/278 (19%), Positives = 103/278 (37%), Gaps = 16/278 (5%)
Query: 246 KKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEAL 305
KK L + + ++ + + + QK+ EK+ E +++ + L L E + + + + L
Sbjct: 1003 KKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLL 1062
Query: 306 KEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDR 365
++ +Q E E ++ L ++ M LR E Q+L+ L G+
Sbjct: 1063 EDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGES 1122
Query: 366 DLCSLD-------TQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKD 418
++L+ QL R E E + R + G L+E + L +
Sbjct: 1123 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQ 1182
Query: 419 QALPVWSPKSFPNEVEPEGTGKEKD---WDLRDQLQKKTLQLQAKEKECRELHSELDNLS 475
+ L E + G+E + +L D L Q + + K +E+ L
Sbjct: 1183 EDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE 1242
Query: 476 DEYLSCLRKLQHCREELNQS------QQLPPRRQCGRW 507
+E +Q R+ Q+ Q RR G W
Sbjct: 1243 EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAW 1280
>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
sapiens]
Length = 805
Score = 61.2 bits (147), Expect = 2e-09
Identities = 79/364 (21%), Positives = 155/364 (42%), Gaps = 48/364 (13%)
Query: 138 KPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVI 197
+P + QT ++ + + +A +KE++QL+++LK+ L L ++K +
Sbjct: 419 QPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRL--SLFSEEKKKL 476
Query: 198 LQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKN 257
+ L + S K Q ++ K K R +E ++K L ++
Sbjct: 477 EEKLKTRDRYISSLKKKCQKESEQNKEKQRRIET-------------LEKYLADLP---- 519
Query: 258 SYEQKAKESLQ-KVLEEK-MNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQ 315
+ + +SLQ ++LEEK N ++ L T++ L +++C++ +Q K+ +
Sbjct: 520 TLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKK-------K 572
Query: 316 HRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDL 375
+EL + + LQ K++ + +R + +QLQ + + L+ + S
Sbjct: 573 EKELVTTVQSLQQKVERC------LEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQ 626
Query: 376 QDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEP 435
QD++ R ++ +Q +QG L + L Q+ + L KK++ + + N+ +
Sbjct: 627 QDEIDR-------MILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQT 679
Query: 436 EGTGKEKDWDLRDQLQKKTLQLQAKEKECRELH--SELDNLSDEYLSCLRKLQHCREELN 493
+ T L DQ Q+ Q R L + +D L E CL L+ LN
Sbjct: 680 DET-----CSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILN 734
Query: 494 QSQQ 497
Q Q
Sbjct: 735 QRAQ 738
Score = 45.8 bits (107), Expect = 1e-04
Identities = 69/289 (23%), Positives = 125/289 (43%), Gaps = 47/289 (16%)
Query: 228 SLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVL--------------EE 273
SL+ Q Y T +P+ + V Q+ +EQK + ++VL EE
Sbjct: 417 SLQPQ-YENTSLQTPFSEESV---SHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEE 472
Query: 274 KMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGA 333
K E++L++ R ++ ++KC++ + E KE R + T LE L L + L
Sbjct: 473 KKKLEEKLKTRDRYISSLKKKCQK---ESEQNKEKQRRIET----LEKYLADLPT-LDDV 524
Query: 334 DSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRV 393
S+ LQ L+ LE +++ LQ + + + QD + QL + ++ LVT V
Sbjct: 525 QSQSLQ----LQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTV 580
Query: 394 QQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNE-----VEPEGTGKEKDWDLRD 448
Q LQ Q+ E+ L + LP+ K NE + E K D +D
Sbjct: 581 QSLQ----------QKVERCL-EDGIRLPMLDAKQLQNENDNLRQQNETASKIID-SQQD 628
Query: 449 QLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
++ + L++Q+ + + + + +E R +Q + L ++Q+
Sbjct: 629 EIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQR 677
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 60.8 bits (146), Expect = 3e-09
Identities = 89/401 (22%), Positives = 168/401 (41%), Gaps = 40/401 (9%)
Query: 144 RGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEAL----QRELVLKQKMVILQ 199
R + +AE K + ++ G+ E +L + +EA E+ LKQK +
Sbjct: 663 RQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYE 722
Query: 200 DLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSY 259
+ + L D+ K L + + +LEN + ++ G K+L E + N+
Sbjct: 723 EKIKVL----DNQIKKDLADKE------TLENMMQRHEEEAHEKG--KILSEQKAMINAM 770
Query: 260 EQKAKESLQKVLE----EKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQ 315
+ K + Q+++E K+ A L TQR++ E+ E R Q L+ L Q
Sbjct: 771 DSKIRSLEQRIVELSEANKLAANSSL-FTQRNMKAQEEMISELRQQKFYLETQAGKLEAQ 829
Query: 316 HRELESQLHVLQSKLQGADSRDLQMNQALR--FLENEHQQLQAKIECLQGDRDLCSLDTQ 373
+R+LE QL + + +R L++ LR LE+E Q+L+ K + + L Q
Sbjct: 830 NRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTE-----LQLSLQ 884
Query: 374 DLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEV 433
+ + QL +A + L ++++Q + L+ + + +E+ + LT + +
Sbjct: 885 ERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEI--------QRKF 936
Query: 434 EPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLS---DEYLSCLRKLQHCRE 490
+ DL +QL + T + L +LD S DE + ++ H R
Sbjct: 937 DALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRR 996
Query: 491 ELNQSQ-QLPPRRQCGRWLPVLMVVIAAALAVFLANKDNLM 530
E+ + + QL ++Q L ++ + A D L+
Sbjct: 997 EITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELL 1037
Score = 42.4 bits (98), Expect = 0.001
Identities = 60/258 (23%), Positives = 106/258 (41%), Gaps = 16/258 (6%)
Query: 168 AVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLR 227
A ++EI L+ + E ++ L+ ++ DL L Q ++ + + L +L
Sbjct: 916 AEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLD 975
Query: 228 SLENQLYTCTQKYSPWG-MKKVLLEMEDQKNSYEQ--KAKESLQKVLEEKMNAEQQLQST 284
Q S +++ + E E Q S +Q +A ++ +LEE++ L++
Sbjct: 976 EASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQV---MDLEAL 1032
Query: 285 QRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQAL 344
L E++ E WRS L ++ + REL+ L + AD R + Q +
Sbjct: 1033 NDELLEKERQWEAWRS---VLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVV 1089
Query: 345 RFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQ- 403
EH +A+I LQ L + L D+L E + L + LQ L+ +
Sbjct: 1090 ELAVKEH---KAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETER 1146
Query: 404 ---SLQLQEQEKLLTKKD 418
L+EQ KL + D
Sbjct: 1147 ELKQRLLEEQAKLQQQMD 1164
Score = 33.5 bits (75), Expect = 0.50
Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 25/200 (12%)
Query: 217 LNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMN 276
L E KLK + SL ++L +K++ M L+ QK E++ K Q++LEE+
Sbjct: 1107 LKEQKLKAE--SLSDKLNDLEKKHAMLEMNARSLQ---QKLETERELK---QRLLEEQAK 1158
Query: 277 AEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSR 336
+QQ+ + + Q +E + + LK T+ +LE QL +Q
Sbjct: 1159 LQQQMDLQKNHIFRLTQGLQEALDRADLLK-------TERSDLEYQLENIQV-------- 1203
Query: 337 DLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQL 396
L ++ ++ +E Q I+ LQ D + + L + K A + + +L
Sbjct: 1204 -LYSHEKVK-MEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNEL 1261
Query: 397 QGLLQNQSLQLQEQEKLLTK 416
+ L+ + + E E+ L K
Sbjct: 1262 KLALEKEKARCAELEEALQK 1281
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 60.1 bits (144), Expect = 5e-09
Identities = 70/333 (21%), Positives = 155/333 (46%), Gaps = 33/333 (9%)
Query: 147 QTKAEGPTIKNDASQQTNYGVA---VLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLS 203
Q +AE + NDA ++ + + L+ ++ ++++ L++ + L K L+D S
Sbjct: 892 QVQAEQDNL-NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECS 950
Query: 204 TLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKA 263
L + D +L K++ + + EN++ T++ + G+ +++ ++ +K + +
Sbjct: 951 ELKKDIDDL---ELTLAKVEKEKHATENKVKNLTEEMA--GLDEIIAKLTKEKKALQ--- 1002
Query: 264 KESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQL 323
E+ Q+ L++ E ++ S +S EQ+ ++ E K+ L R+LE L
Sbjct: 1003 -EAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061
Query: 324 HVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSE 383
+ Q + ++ LQ+ + L+ E + Q +KIE D + +L LQ +LK ++
Sbjct: 1062 KLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE----DEQVLAL---QLQKKLKENQ 1114
Query: 384 AEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPK------SFPNEVEPEG 437
A R+++L+ L+ + + EKL + + L S + + ++E
Sbjct: 1115 A-------RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1167
Query: 438 TGKEKDWDLRDQLQKKTLQLQAKEKECRELHSE 470
+ + +R L++ TLQ +A R+ H++
Sbjct: 1168 KREAEFQKMRRDLEEATLQHEATAAALRKKHAD 1200
Score = 54.3 bits (129), Expect = 3e-07
Identities = 69/313 (22%), Positives = 131/313 (41%), Gaps = 45/313 (14%)
Query: 221 KLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQ 280
K+K L+S E + T K +K+ L + E ++ E+K + +L+EK + + Q
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEK----MVSLLQEKNDLQLQ 892
Query: 281 LQSTQRSLALAEQKCEEW---RSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGA---- 333
+Q+ Q +L AE++C++ + Q EA ++ E+ ++L + KL+
Sbjct: 893 VQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 952
Query: 334 --DSRDLQMNQALRFLENEHQQLQAKIE---------------------CLQGDRDLCSL 370
D DL++ A +E E + K++ LQ
Sbjct: 953 KKDIDDLELTLAK--VEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALD 1010
Query: 371 DTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFP 430
D Q +D++ K+ L +V L+G L+ + + E+ K + L +
Sbjct: 1011 DLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMD 1070
Query: 431 NE---VEPEGTGKEKDWDLRDQLQK------KTLQLQAKEKECRELHSELDNLSDEYLSC 481
E ++ E K+K++D+ Q K LQLQ K KE + EL+ + +
Sbjct: 1071 LENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTA 1130
Query: 482 LRKLQHCREELNQ 494
K++ R +L++
Sbjct: 1131 RAKVEKLRSDLSR 1143
Score = 53.5 bits (127), Expect = 5e-07
Identities = 109/506 (21%), Positives = 201/506 (39%), Gaps = 70/506 (13%)
Query: 12 LARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNL 71
LA W + YE E + E+ S++ +++T K + E L+ F+R N
Sbjct: 1455 LAEWKQKYE---ESQSELESSQKEARSLSTELFKLKNAYEESLEHLET------FKRENK 1505
Query: 72 ELEEKGKAQHPQAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPP 131
L+E+ Q E G + + EV + L L L
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLE----------LQSALEEAEASLEH 1555
Query: 132 QDTPIKKPPKHHRGTQTKAEGPTIKNDAS--QQTNYGVAVLDKEIIQLSDYLKEALQREL 189
++ I + + + E + D Q V+D L E R
Sbjct: 1556 EEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLD---AETRSRNE 1612
Query: 190 VLKQKMVILQDLLSTLIQASDSSW---KGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMK 246
VL+ K + DL IQ S ++ + Q L+ L+ + QL +
Sbjct: 1613 VLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDL--- 1669
Query: 247 KVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALK 306
K + + +++N+ Q E L+ V+E+ T+RS LAEQ+ E + + L
Sbjct: 1670 KENIAIVERRNNLLQAELEELRAVVEQ----------TERSRKLAEQELIETSERVQLLH 1719
Query: 307 EDWRTLGTQHRELESQLHVLQSKLQGA--------DSRDLQMNQALRFLE--NEHQQLQA 356
+L Q +++ES L LQS+++ A + + A E + Q A
Sbjct: 1720 SQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSA 1779
Query: 357 KIECLQGDRDLCSLDTQDLQDQ-----LKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE 411
+E ++ + + D Q D+ LK + + L RV++L+G L+ + + E
Sbjct: 1780 HLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESV 1839
Query: 412 KLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSEL 471
K + K ++ + K + E + + DL D+LQ L+++A +++ E +
Sbjct: 1840 KGMRKSERRI-----KELTYQTEEDKKNLLRLQDLVDKLQ---LKVKAYKRQAEEAEEQ- 1890
Query: 472 DNLSDEYLSCLRKLQHCREELNQSQQ 497
++ LS RK+QH EL+++++
Sbjct: 1891 ---ANTNLSKFRKVQH---ELDEAEE 1910
Score = 46.2 bits (108), Expect = 7e-05
Identities = 61/268 (22%), Positives = 100/268 (37%), Gaps = 45/268 (16%)
Query: 251 EMEDQKNSYEQ--KAKESLQKVL--------------EEKMNAEQQLQSTQRSLALAEQK 294
+MED K E+ KAK +L L EE+ A+ +LQ R L+ A +
Sbjct: 1313 QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ---RVLSKANSE 1369
Query: 295 CEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQL 354
+WR++YE + ELE L +LQ A+ +N LE +L
Sbjct: 1370 VAQWRTKYET------DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRL 1423
Query: 355 QAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLL 414
Q +IE DL ++RS A L + + +L + +E + L
Sbjct: 1424 QNEIE--------------DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1469
Query: 415 TKKDQALPVWSPK------SFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELH 468
+ S + ++ +E T K ++ +L++++ T QL K EL
Sbjct: 1470 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Query: 469 SELDNLSDEYLSCLRKLQHCREELNQSQ 496
L E L L+ L +
Sbjct: 1530 KVRKQLEVEKLELQSALEEAEASLEHEE 1557
Score = 43.5 bits (101), Expect = 5e-04
Identities = 71/373 (19%), Positives = 165/373 (44%), Gaps = 42/373 (11%)
Query: 161 QQTNYGVAVLDKEIIQLSDYLKEALQR------ELVLKQKMVILQDLLSTLIQASDSSWK 214
+++N A LDK+ L E Q+ EL QK + L + L + ++ +
Sbjct: 1435 ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEA--RSLSTELFKLKNAYEE 1492
Query: 215 GQLNEDKLKGKLRSLENQLYTCTQKYSPWG-----MKKVLLEMEDQK---NSYEQKAKES 266
+ + K + ++L+ ++ T++ G ++KV ++E +K S ++A+ S
Sbjct: 1493 SLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEAS 1552
Query: 267 LQ----KVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRT-LGTQHRELES 321
L+ K+L ++ Q +R LA +++ E+ + ++ + + +T L + R
Sbjct: 1553 LEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNE 1612
Query: 322 QLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLK- 380
L V + + ++Q++ A R +Q+++ ++ L D + D D LK
Sbjct: 1613 VLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS-LQSLLKDTQIQLDDAVRANDDLKE 1671
Query: 381 ------------RSEAEKL-TLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPK 427
++E E+L +V + ++ + L + + ++ E+ +LL ++ +L K
Sbjct: 1672 NIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1731
Query: 428 SFPNEVEPEGTGKEKDWDLR--DQLQKKTL---QLQAKE-KECRELHSELDNLSDEYLSC 481
+ + + +E + R ++ KK + + A+E K+ ++ + L+ +
Sbjct: 1732 MESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT 1791
Query: 482 LRKLQHCREELNQ 494
++ LQH +E Q
Sbjct: 1792 IKDLQHRLDEAEQ 1804
Score = 42.7 bits (99), Expect = 8e-04
Identities = 62/274 (22%), Positives = 116/274 (42%), Gaps = 32/274 (11%)
Query: 245 MKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQ--- 301
++KV +EDQ N Y K +E+ Q+ L + +LQ+ LA ++ E SQ
Sbjct: 1247 LEKVSRTLEDQANEYRVKLEEA-QRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTR 1305
Query: 302 ----YEALKEDW-RTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQA 356
Y ED R L + + + H LQS D LR E + +A
Sbjct: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCD--------LLREQYEEETEAKA 1357
Query: 357 KIECL--QGDRDLCSLDTQDLQDQLKRS---EAEKLTLVTRVQQLQGLLQNQSLQLQEQE 411
+++ + + + ++ T+ D ++R+ E K L R+Q + ++ + + E
Sbjct: 1358 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLE 1417
Query: 412 KL---LTKKDQALPVWSPKSFPNEVEPEGTGKEKDWD-----LRDQLQKKTLQLQAKEKE 463
K L + + L V +S N K++++D + + ++ +L++ +KE
Sbjct: 1418 KTKHRLQNEIEDLMVDVERS--NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKE 1475
Query: 464 CRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
R L +EL L + Y L L+ + E Q+
Sbjct: 1476 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Score = 36.2 bits (82), Expect = 0.077
Identities = 44/230 (19%), Positives = 86/230 (37%), Gaps = 60/230 (26%)
Query: 245 MKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCE-------- 296
+ K E+ + YE A + +++ E K Q+LQ + ++ KC
Sbjct: 1363 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHR 1422
Query: 297 ----------------------------------EWRSQYEALKEDWRTLGTQHRELESQ 322
EW+ +YE + + + + R L ++
Sbjct: 1423 LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTE 1482
Query: 323 LHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS 382
L KL+ A L + L + E++ LQ +I L + +L+ K+
Sbjct: 1483 LF----KLKNAYEESL---EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQL 1535
Query: 383 EAEKLTLVTRVQQLQGLLQNQS-----LQLQ------EQEKLLTKKDQAL 421
E EKL L + +++ + L+++ QL+ E E+ L +KD+ +
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEM 1585
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 59.7 bits (143), Expect = 6e-09
Identities = 85/394 (21%), Positives = 164/394 (41%), Gaps = 64/394 (16%)
Query: 162 QTNYGVAVLDKEIIQLSDYLKEA----------LQRELVLKQKMVILQDLLSTLIQASDS 211
+T+ ++ ++EI+ L L+EA LQ +L Q+ + +D +Q
Sbjct: 1768 ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ 1827
Query: 212 SWKGQLNEDKLKGKLRSLENQL----YTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESL 267
+GQ E+++K K +L+ L T +++ K +++ + E + ++L
Sbjct: 1828 QAQGQ--EERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQAL 1885
Query: 268 QKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYE----ALKEDWRTLGTQHRELESQL 323
++VL + + AE + Q +++L +Q+C E ++E AL++ W +E + +L
Sbjct: 1886 EEVLGD-LRAESREQ--EKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQEL 1942
Query: 324 HVLQSK----------------------------LQGADSRDLQMNQALRFLENEHQQLQ 355
L+++ LQG + L+ + R LE LQ
Sbjct: 1943 EALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQ 2002
Query: 356 AKIECLQGDRDLCSLDTQDLQDQLKRSEAE----KLTLVTRVQQLQGLLQNQSLQLQEQE 411
A + D C ++ L++ L+ E E L VQQLQ L + +L+ Q+
Sbjct: 2003 ASL-------DACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQ 2055
Query: 412 KLLTKKDQALPVWSPKSFPNEVEPEGTGKEKD--WDLRDQLQKKTLQLQAKEKECRELHS 469
+ +++L ++ E + G +E++ L +++ L L KE+E EL
Sbjct: 2056 EREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRE 2115
Query: 470 ELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQ 503
+ E L K E+ + L PR Q
Sbjct: 2116 TQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQ 2149
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/286 (25%), Positives = 126/286 (44%), Gaps = 31/286 (10%)
Query: 246 KKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWR----SQ 301
K+ + +EDQ+ + +E L+++ ++L +TQR L +++ EE + +Q
Sbjct: 1664 KERIQVLEDQRTRQTKILEEDLEQIKLSLRERGREL-TTQRQLM--QERAEEGKGPSKAQ 1720
Query: 302 YEALKEDWRTLGTQHRELESQ---LHVLQS-------KLQGADSRDLQMNQALRFLENEH 351
+L+ L + +E+E Q +H LQ +LQG + + + L
Sbjct: 1721 RGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRK---VGETSLLLSQRE 1777
Query: 352 QQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE 411
Q++ + LQ R+ L Q LQ QL EA++ L R Q+L+ L Q Q Q Q QE
Sbjct: 1778 QEIVVLQQQLQEAREQGELKEQSLQSQL--DEAQR-ALAQRDQELEALQQEQQ-QAQGQE 1833
Query: 412 KLLTKKDQALPVWSPKSFPNEVEPEG---TGKEKDWDLRDQLQKKTLQLQAKEKECRELH 468
+ + +K AL ++ E G KE+ L ++L + ++QA E+ +L
Sbjct: 1834 ERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLR 1893
Query: 469 SELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVV 514
+E S E L LQ E Q ++ R WL V+
Sbjct: 1894 AE----SREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVL 1935
Score = 47.4 bits (111), Expect = 3e-05
Identities = 71/290 (24%), Positives = 132/290 (45%), Gaps = 30/290 (10%)
Query: 214 KGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEE 273
K Q+ E + +G+++ L+ QL T ++ + LE+E+ N ++ + ++ L K LE
Sbjct: 1534 KDQMIESQ-RGQVQDLKKQLVT---------LECLALELEE--NHHKMECQQKLIKELEG 1581
Query: 274 KMNAEQQLQSTQRSLALAE--QKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQ 331
+ Q++ T +L L E Q+ + SQ L+ L REL+ + ++S+ +
Sbjct: 1582 QRET-QRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLA---RELQERDQEVKSQRE 1637
Query: 332 GADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVT 391
+ Q + LE Q+L + E +Q D + T+ L++ L E KL+L
Sbjct: 1638 QIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDL---EQIKLSLRE 1694
Query: 392 RVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKD----WDLR 447
R ++L Q Q +Q + +E K Q + K + E E +++ +L+
Sbjct: 1695 RGREL--TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELK 1752
Query: 448 DQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQ 497
DQL++ QLQ ++ E L E + ++LQ RE+ +Q
Sbjct: 1753 DQLEQ---QLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQ 1799
Score = 47.0 bits (110), Expect = 4e-05
Identities = 80/339 (23%), Positives = 133/339 (39%), Gaps = 46/339 (13%)
Query: 180 YLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNED-KLKGKLRSLENQLYTCTQ 238
YLK R L L +++V + + A+D E +L G L + +L Q
Sbjct: 169 YLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQ 228
Query: 239 KYSPWGMKKV-------LLEMEDQKNSYEQKAKESLQKVLE-------EKMNAEQQLQST 284
P G ++ LL + + E++A E Q++++ EK + ++
Sbjct: 229 SREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTEL 288
Query: 285 QRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQAL 344
L ++++ E++ +AL+E L T H EL + S + A L + Q +
Sbjct: 289 SALLTQSQKQNEDYEKMIKALRETVEILETNHTEL---MEHEASLSRNAQEEKLSLQQVI 345
Query: 345 RFLENEHQQLQAKIECLQGDRDLCSLDTQ-----DLQDQLKRSEAEKLTLVTRVQQLQGL 399
+ + + I G + LD+ D QD K + L R Q +Q L
Sbjct: 346 KDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDL 405
Query: 400 LQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQA 459
Q Q QE LL ++ ++ E EG LR +LQK T +
Sbjct: 406 RQ-QLAGCQEAVNLLQQQH------------DQWEEEGKA------LRQRLQKLTGERDT 446
Query: 460 KEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQL 498
+ +L E+D+LS E LQ REEL Q ++
Sbjct: 447 LAGQTVDLQGEVDSLSKE----RELLQKAREELRQQLEV 481
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/250 (24%), Positives = 108/250 (43%), Gaps = 32/250 (12%)
Query: 261 QKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELE 320
QK +E L EK +LQ QR L+ +++ +W + +L+ ++ EL
Sbjct: 1267 QKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLE-------SELMELH 1319
Query: 321 SQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQ-------GDRDLCSLDTQ 373
+ LQS+L+ A+ + ++ L+ + L A++E LQ + +
Sbjct: 1320 ETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEE 1379
Query: 374 DLQD-----QLKRSEAEKLTLVTRVQQLQGLLQ-NQSLQLQEQEKLLTKKDQALPVWSPK 427
DL+ +LK E E + Q QG L+ Q LQE LLT+ +
Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQ--------TLA 1431
Query: 428 SFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQH 487
EVE G+ ++ + + ++QK L+L + + + R + E+D L E + L K +
Sbjct: 1432 EREEEVETL-RGQIQELEKQREMQKAALELLSLDLKKR--NQEVD-LQQEQIQELEKCRS 1487
Query: 488 CREELNQSQQ 497
E L + Q
Sbjct: 1488 VLEHLPMAVQ 1497
Score = 46.6 bits (109), Expect = 6e-05
Identities = 120/545 (22%), Positives = 218/545 (40%), Gaps = 71/545 (13%)
Query: 14 RWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRAR---------LQQ 64
+W E +A +R Q++ R T Q ++RE LQ+AR L+Q
Sbjct: 425 QWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQ 484
Query: 65 F---FRRRNLELEEKGKAQHPQAREQGPSRRPG-QVTGTSSEVFPAQHPPPSGICRDL-- 118
RR N+EL+ +G + Q EQ + E+ S +L
Sbjct: 485 EAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELIT 544
Query: 119 ------SDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDK 172
S HL + L + T + R Q+ AE + +N + VA L
Sbjct: 545 LREALESSHLEGEL--LRQEQTEVTAALA--RAEQSIAELSSSENTLKTE----VADLRA 596
Query: 173 EIIQLSDYLKEALQRELV-LKQKMVILQD-------LLSTLIQASDSSWKGQLNEDKLKG 224
++LS L EAL + V L Q+++ L++ + QA ++ +K +
Sbjct: 597 AAVKLSA-LNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRRE 655
Query: 225 KLRSLENQLYTCTQKYSPWG--MKKVLLEMEDQKNSYEQKAKES----------LQKVLE 272
L L QK G ++ L +++++K ++K ES L+++ +
Sbjct: 656 ALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQ 715
Query: 273 EKMNAEQQL-QSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQ 331
E E+ L ++ Q AL +K + +A++ D + L Q + L S +L+S L
Sbjct: 716 EAKRQEEVLARAVQEKEALVREKAA-LEVRLQAVERDRQDLAEQLQGLSSAKELLESSLF 774
Query: 332 GADSRDL-------QMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEA 384
A ++ Q+ ++ + + +Q ++ CL+ LDT+ Q + +R A
Sbjct: 775 EAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLK-----LELDTERSQAEQERDAA 829
Query: 385 EKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEP-EGTGKEKD 443
+ L Q+ + L+ Q +++ L +K + W + +E E E +
Sbjct: 830 AR-QLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELE 888
Query: 444 WDLRDQLQKKTLQLQAKEKECRELHSELDNL----SDEYLSCLRKLQHCREEL-NQSQQL 498
L++Q + +E+E + S L + E +S L L ++EL + SQQL
Sbjct: 889 MRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQL 948
Query: 499 PPRRQ 503
RQ
Sbjct: 949 ERLRQ 953
Score = 46.6 bits (109), Expect = 6e-05
Identities = 68/320 (21%), Positives = 139/320 (43%), Gaps = 18/320 (5%)
Query: 185 LQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWG 244
+Q + V + K VI ++ ++ + + D +L E + T ++
Sbjct: 792 VQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAH 851
Query: 245 MKKVLL---EMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQ 301
K+V + E +++ ++Q+ ++L+ + EKM E +L+ Q + + + EE R+Q
Sbjct: 852 EKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQ 911
Query: 302 YEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECL 361
E+ + L T+ + +LQ++ + AD A + LE Q ++ +
Sbjct: 912 AESALCQMQ-LETEKERVSLLETLLQTQKELAD--------ASQQLERLRQDMKVQKLKE 962
Query: 362 QGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQAL 421
Q + Q+ Q +LK + + + +Q+ L + LQ+Q + L K
Sbjct: 963 QETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDL-KSQLVA 1021
Query: 422 PVWSPKSFPNEVEPEGTGKEKDWDLRDQL--QKKTLQLQAKEKECREL-HSELDNLSDEY 478
S + EV+ + ++ ++ +L +K +L L EKE R L E D++ +
Sbjct: 1022 QDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQE 1081
Query: 479 LSCLRKLQHCREELNQSQQL 498
LS LR Q +E + ++L
Sbjct: 1082 LSALR--QDMQEAQGEQKEL 1099
Score = 44.3 bits (103), Expect = 3e-04
Identities = 69/340 (20%), Positives = 147/340 (43%), Gaps = 52/340 (15%)
Query: 182 KEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYS 241
+ A + +L L+Q +++D+ +++ D+ +G +E+ L+ L++ +++
Sbjct: 332 RNAQEEKLSLQQ---VIKDITQVMVEEGDNIAQGSGHENSLE-----LDSSIFS------ 377
Query: 242 PWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNA----EQQLQSTQRSLALAEQKCEE 297
+ +D KA ++ VL + A QQL Q ++ L +Q+ ++
Sbjct: 378 -------QFDYQDA-----DKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQ 425
Query: 298 WRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQG-ADSRDL------QMNQALRFLENE 350
W + +AL++ + L + L Q LQ ++ + R+L ++ Q L LE E
Sbjct: 426 WEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQE 485
Query: 351 -------HQQLQAKIECLQGDRD-------LCSLDTQDLQDQLKRSEAEKLTLVTRVQQL 396
+ +LQ + + QG ++ L + + LQ+ L EA++ ++ + L
Sbjct: 486 AWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITL 545
Query: 397 QGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQ 456
+ L++ L+ + + T+ AL + +S E T K + DLR K +
Sbjct: 546 REALESSHLEGELLRQEQTEVTAAL-ARAEQSIAELSSSENTLKTEVADLRAAAVKLSAL 604
Query: 457 LQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQ 496
+A + L+ +L L +E S +++ + N Q
Sbjct: 605 NEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQ 644
Score = 43.1 bits (100), Expect = 6e-04
Identities = 79/356 (22%), Positives = 142/356 (39%), Gaps = 50/356 (14%)
Query: 170 LDKEIIQLSDYLKEALQRELVLKQKM-VILQDLLSTLIQASDSSWKGQLNEDKLKGKLRS 228
L E ++ +ALQ + LK LQ+ L+ L Q + + L+G+++
Sbjct: 1390 LKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAER---EEEVETLRGQIQE 1446
Query: 229 LENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSL 288
LE Q M+K LE+ + + Q+ ++E L+ ++
Sbjct: 1447 LEKQRE----------MQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAV 1496
Query: 289 ALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQ------ 342
EQK R Q L++D TQ LE QL L+ K Q +S+ Q+
Sbjct: 1497 QEREQKLTVQREQIRELEKDRE---TQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLV 1553
Query: 343 -----ALRFLENEHQQ--LQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQ 395
AL EN H+ Q I+ L+G R+ + L L+ E +++
Sbjct: 1554 TLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHD 1613
Query: 396 LQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQ---LQK 452
L+ + +LQE+++ V S + E++ + +D + RDQ LQK
Sbjct: 1614 LESHSTVLARELQERDQ---------EVKSQREQIEELQRQKEHLTQDLERRDQELMLQK 1664
Query: 453 KTLQL--QAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGR 506
+ +Q+ + ++ + L +L+ + L + RE Q Q + R + G+
Sbjct: 1665 ERIQVLEDQRTRQTKILEEDLEQIK------LSLRERGRELTTQRQLMQERAEEGK 1714
Score = 38.1 bits (87), Expect = 0.020
Identities = 111/489 (22%), Positives = 188/489 (38%), Gaps = 63/489 (12%)
Query: 17 ESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLELE-E 75
E+ +A+ E + ES C+ + T ++ L + Q + A Q R +++ +
Sbjct: 899 EAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQ 958
Query: 76 KGKAQHP----QAREQGPSRRPGQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPP 131
K K Q Q + Q R + + A S + +D D L Q L
Sbjct: 959 KLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMD-LQKQVEDLKS 1017
Query: 132 QDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVL 191
Q + R + + + K +Q+ N L++E L+ L E QR LVL
Sbjct: 1018 Q---LVAQDDSQRLVEQEVQE---KLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVL 1071
Query: 192 KQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLE 251
++ I Q LS L Q + Q + +L ++ L ++ + + LLE
Sbjct: 1072 QEADSIRQQELSALRQDMQEA---QGEQKELSAQMELLRQEVKEKEADFL--AQEAQLLE 1126
Query: 252 MEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQ---RSLALAEQKCEEWRSQ------Y 302
+ + EQ+ + SL + + +L+ST+ +LA +Q + ++Q Y
Sbjct: 1127 ELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLY 1186
Query: 303 EALKEDWRTLGTQHRELES------QLHVLQSKLQGADS--------RDLQMNQALRFLE 348
AL++ ++ EL + L+ GA S L L
Sbjct: 1187 SALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALH 1246
Query: 349 NEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQ-GLLQNQSLQL 407
HQ L Q RD+ Q L+++L +EAEK + T +Q LQ L QNQ
Sbjct: 1247 KLHQDLWKT----QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQ---- 1298
Query: 408 QEQEKLLTKKDQALPVWSPKSFPNEVEPEGTG-KEKDWDLRDQLQKKTLQLQAKEKECRE 466
+E+ K W K N +E E E L+ +L++ LQ + E
Sbjct: 1299 EEKSK-----------WEGKQ--NSLESELMELHETMASLQSRLRRAELQRMEAQGEREL 1345
Query: 467 LHSELDNLS 475
L + +NL+
Sbjct: 1346 LQAAKENLT 1354
Score = 32.0 bits (71), Expect = 1.4
Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 33/245 (13%)
Query: 252 MEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEA-LKEDWR 310
ME + +SLQ VLEE++ A QQ + ++ + + K + Q +A L +
Sbjct: 1 METRSPGLNNMKPQSLQLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQ 60
Query: 311 TLGTQHR----ELESQLHVLQSKL--QGADSRDLQMNQALRFLENEHQQLQAKIECLQGD 364
Q+R ELE +L + + + + +++ L LE E Q+ ++ E
Sbjct: 61 AKVLQYRSWCQELEKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQL 120
Query: 365 RDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQE----KLLTKKDQA 420
R ++ D+ ++ R + EKLT V + L++ +S EQE L + +
Sbjct: 121 R--LHMEKADVVNKALREDVEKLT-VDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRL 177
Query: 421 LPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLS 480
L +W +E R L+ K+ A +++ EL +E LS L+
Sbjct: 178 LSLW---------------REVVTFRRHFLEMKS----ATDRDLMELKAEHVRLSGSLLT 218
Query: 481 CLRKL 485
C +L
Sbjct: 219 CCLRL 223
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,420,817
Number of Sequences: 37866
Number of extensions: 1039491
Number of successful extensions: 9231
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 798
Number of HSP's that attempted gapping in prelim test: 5409
Number of HSP's gapped (non-prelim): 3041
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.