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Search of human proteins with 134304851
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3
[Homo sapiens]
(836 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H... 1675 0.0
gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre... 1675 0.0
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr... 1657 0.0
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p... 1313 0.0
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p... 1283 0.0
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p... 1271 0.0
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p... 1265 0.0
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H... 1226 0.0
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H... 1217 0.0
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ... 609 e-174
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ... 609 e-174
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ... 594 e-170
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ... 592 e-169
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p... 582 e-166
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens] 509 e-144
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens] 507 e-143
gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 477 e-134
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 477 e-134
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H... 343 3e-94
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens] 339 7e-93
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens] 235 1e-61
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens] 235 1e-61
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens] 235 1e-61
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ... 187 3e-47
gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [... 182 1e-45
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 175 1e-43
gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2 ... 172 2e-42
gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1 ... 172 2e-42
gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1 pr... 172 2e-42
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate... 165 2e-40
>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
sapiens]
Length = 836
Score = 1675 bits (4338), Expect = 0.0
Identities = 836/836 (100%), Positives = 836/836 (100%)
Query: 1 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 60
MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL
Sbjct: 1 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 60
Query: 61 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120
HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS
Sbjct: 61 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120
Query: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180
AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG
Sbjct: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180
Query: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240
KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG
Sbjct: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240
Query: 241 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 300
AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA
Sbjct: 241 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 300
Query: 301 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 360
LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND
Sbjct: 301 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 360
Query: 361 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 420
TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG
Sbjct: 361 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 420
Query: 421 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 480
DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK
Sbjct: 421 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 480
Query: 481 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 540
PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE
Sbjct: 481 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 540
Query: 541 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 600
STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV
Sbjct: 541 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 600
Query: 601 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT
Sbjct: 601 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
Query: 661 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 720
AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV
Sbjct: 661 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 720
Query: 721 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 780
NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA
Sbjct: 721 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 780
Query: 781 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 781 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
precursor [Homo sapiens]
Length = 883
Score = 1675 bits (4338), Expect = 0.0
Identities = 836/836 (100%), Positives = 836/836 (100%)
Query: 1 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 60
MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL
Sbjct: 48 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 107
Query: 61 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120
HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS
Sbjct: 108 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 167
Query: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180
AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG
Sbjct: 168 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 227
Query: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240
KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG
Sbjct: 228 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 287
Query: 241 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 300
AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA
Sbjct: 288 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 347
Query: 301 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 360
LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND
Sbjct: 348 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 407
Query: 361 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 420
TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG
Sbjct: 408 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 467
Query: 421 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 480
DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK
Sbjct: 468 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 527
Query: 481 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 540
PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE
Sbjct: 528 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 587
Query: 541 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 600
STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV
Sbjct: 588 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 647
Query: 601 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT
Sbjct: 648 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
Query: 661 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 720
AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV
Sbjct: 708 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 767
Query: 721 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 780
NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA
Sbjct: 768 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 827
Query: 781 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 828 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
precursor [Homo sapiens]
Length = 883
Score = 1657 bits (4291), Expect = 0.0
Identities = 827/836 (98%), Positives = 830/836 (99%)
Query: 1 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 60
MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL
Sbjct: 48 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 107
Query: 61 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120
HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS
Sbjct: 108 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 167
Query: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180
AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG
Sbjct: 168 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 227
Query: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240
KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG
Sbjct: 228 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 287
Query: 241 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 300
AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA
Sbjct: 288 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 347
Query: 301 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 360
LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND
Sbjct: 348 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 407
Query: 361 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 420
TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG
Sbjct: 408 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 467
Query: 421 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 480
DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK
Sbjct: 468 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 527
Query: 481 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 540
PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE
Sbjct: 528 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 587
Query: 541 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 600
STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV
Sbjct: 588 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 647
Query: 601 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT
Sbjct: 648 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
Query: 661 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 720
AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR V
Sbjct: 708 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAV 767
Query: 721 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 780
NLAVLKL+EQG+LDKLKNKWWYDKGECG+ SKEKTSALSLSNVAGVFYILVGGLGLA
Sbjct: 768 NLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLA 827
Query: 781 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 828 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
precursor [Homo sapiens]
Length = 884
Score = 1313 bits (3399), Expect = 0.0
Identities = 628/832 (75%), Positives = 736/832 (88%), Gaps = 5/832 (0%)
Query: 5 STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64
S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S
Sbjct: 58 SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
Query: 65 ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
ITPSFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +
Sbjct: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
Query: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
W V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
Query: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244
GYHYIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T
Sbjct: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
Query: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304
KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
Query: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364
+++GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +
Sbjct: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
Query: 365 ENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKY 424
EN+TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKY
Sbjct: 413 ENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKY 472
Query: 425 GARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 484
GARDADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS
Sbjct: 473 GARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 532
Query: 485 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE 544
KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E S + NE
Sbjct: 533 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNE 592
Query: 545 FGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 604
FGIFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV
Sbjct: 593 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 652
Query: 605 SPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGV 664
SPIESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGV
Sbjct: 653 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 712
Query: 665 ARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAV 724
ARVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL VNLAV
Sbjct: 713 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAV 772
Query: 725 LKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVA 784
LKL+EQG+LDKLKNKWWYDKGECG+ SK+KTSALSLSNVAGVFYILVGGLGLAMLVA
Sbjct: 773 LKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832
Query: 785 LIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
LIEFCYKSRAEAKRMKVAK+AQ NP+SSQN+QN ATY+EGYNVYG ES+KI
Sbjct: 833 LIEFCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
precursor [Homo sapiens]
Length = 894
Score = 1283 bits (3320), Expect = 0.0
Identities = 617/830 (74%), Positives = 733/830 (88%), Gaps = 6/830 (0%)
Query: 9 FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPS 68
F L H+D+L+ +NSF+VTNAFCSQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPS
Sbjct: 69 FHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPS 128
Query: 69 FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQV 128
FPTD FVIQMRP LKGA+LSL+ +Y+W+KF YLYD++RG S LQA++++A + WQV
Sbjct: 129 FPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQV 188
Query: 129 TAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHY 188
TA +VGNI K + +R + ++++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY
Sbjct: 189 TARSVGNI---KDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHY 245
Query: 189 IIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKY 248
++ANLGFTD L ++ GGAN++GFQIV+ ++ +V +FI+RW L+E+E+P A +KY
Sbjct: 246 MLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 305
Query: 249 TSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 308
TSALT+DA+ V+ EAFR LR+QR+++SRRG+AGDCLANPAVPW QG++IERALK VQV+G
Sbjct: 306 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 365
Query: 309 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 368
++GNI+FD G+R NYTI++ E+K +G RK GYW+E ++ V ++ ND++ EN+T
Sbjct: 366 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFV-PFSDQQISNDSASSENRT 424
Query: 369 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 428
+VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH KYKL+IVGDGKYGARD
Sbjct: 425 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 484
Query: 429 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 488
+TKIWNGMVGELVYG+ADIA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV
Sbjct: 485 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 544
Query: 489 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF-EDGRETQSS-ESTNEFG 546
FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ E+ R+ QS + NEFG
Sbjct: 545 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFG 604
Query: 547 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 606
IFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP
Sbjct: 605 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 664
Query: 607 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR 666
IESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVAR
Sbjct: 665 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVAR 724
Query: 667 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLK 726
VRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L TPVNLAVLK
Sbjct: 725 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLK 784
Query: 727 LSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI 786
LSEQG+LDKLKNKWWYDKGECGAKDSGSK+KTSALSLSNVAGVFYILVGGLGLAM+VALI
Sbjct: 785 LSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALI 844
Query: 787 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
EFCYKSRAE+KRMK+ KN QN P+ + N+QN+ATY+EGYNVYG ESVKI
Sbjct: 845 EFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894
>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
precursor [Homo sapiens]
Length = 902
Score = 1271 bits (3289), Expect = 0.0
Identities = 608/797 (76%), Positives = 709/797 (88%), Gaps = 5/797 (0%)
Query: 5 STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64
S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S
Sbjct: 58 SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
Query: 65 ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
ITPSFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +
Sbjct: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
Query: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
W V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
Query: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244
GYHYIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T
Sbjct: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
Query: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304
KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
Query: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364
+++GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +
Sbjct: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
Query: 365 ENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKY 424
EN+TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKY
Sbjct: 413 ENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKY 472
Query: 425 GARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 484
GARDADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS
Sbjct: 473 GARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 532
Query: 485 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE 544
KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E S + NE
Sbjct: 533 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNE 592
Query: 545 FGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 604
FGIFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV
Sbjct: 593 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 652
Query: 605 SPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGV 664
SPIESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGV
Sbjct: 653 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 712
Query: 665 ARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAV 724
ARVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL TPVNLAV
Sbjct: 713 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAV 772
Query: 725 LKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVA 784
LKLSE GVLDKLKNKWWYDKGECG KDSGSK+KTSALSLSNVAGVFYILVGGLGLAMLVA
Sbjct: 773 LKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832
Query: 785 LIEFCYKSRAEAKRMKV 801
LIEFCYKSRAEAKRMK+
Sbjct: 833 LIEFCYKSRAEAKRMKL 849
>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
precursor [Homo sapiens]
Length = 894
Score = 1265 bits (3274), Expect = 0.0
Identities = 609/830 (73%), Positives = 727/830 (87%), Gaps = 6/830 (0%)
Query: 9 FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPS 68
F L H+D+L+ +NSF+VTNAFCSQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPS
Sbjct: 69 FHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPS 128
Query: 69 FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQV 128
FPTD FVIQMRP LKGA+LSL+ +Y+W+KF YLYD++RG S LQA++++A + WQV
Sbjct: 129 FPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQV 188
Query: 129 TAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHY 188
TA +VGNI K + +R + ++++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY
Sbjct: 189 TARSVGNI---KDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHY 245
Query: 189 IIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKY 248
++ANLGFTD L ++ GGAN++GFQIV+ ++ +V +FI+RW L+E+E+P A +KY
Sbjct: 246 MLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 305
Query: 249 TSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 308
TSALT+DA+ V+ EAFR LR+QR+++SRRG+AGDCLANPAVPW QG++IERALK VQV+G
Sbjct: 306 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 365
Query: 309 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 368
++GNI+FD G+R NYTI++ E+K +G RK GYW+E ++ V ++ ND++ EN+T
Sbjct: 366 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFV-PFSDQQISNDSASSENRT 424
Query: 369 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 428
+VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH KYKL+IVGDGKYGARD
Sbjct: 425 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 484
Query: 429 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 488
+TKIWNGMVGELVYG+ADIA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV
Sbjct: 485 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 544
Query: 489 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF-EDGRETQSS-ESTNEFG 546
FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ E+ R+ QS + NEFG
Sbjct: 545 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFG 604
Query: 547 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 606
IFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP
Sbjct: 605 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 664
Query: 607 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR 666
IESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVAR
Sbjct: 665 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVAR 724
Query: 667 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLK 726
VRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L VNLAVLK
Sbjct: 725 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLK 784
Query: 727 LSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI 786
L+EQG+LDKLKNKWWYDKGECG+ SK+KTSALSLSNVAGVFYILVGGLGLAM+VALI
Sbjct: 785 LNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALI 844
Query: 787 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
EFCYKSRAE+KRMK+ KN QN P+ + N+QN+ATY+EGYNVYG ESVKI
Sbjct: 845 EFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894
>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
sapiens]
Length = 906
Score = 1226 bits (3173), Expect = 0.0
Identities = 587/791 (74%), Positives = 697/791 (88%), Gaps = 4/791 (0%)
Query: 10 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSF 69
+L P ID + +++SF +T FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSF
Sbjct: 54 KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSF 113
Query: 70 PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVT 129
P D ++ FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVT
Sbjct: 114 PVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVT 173
Query: 130 AINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYI 189
A+N+ +E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+ GYHYI
Sbjct: 174 AVNILTTT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYI 229
Query: 190 IANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYT 249
+ANLGF D DL K + GANV+GFQ+V+Y D++ +K +++W + +++ KYT
Sbjct: 230 LANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYT 289
Query: 250 SALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGL 309
SALTYD V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL
Sbjct: 290 SALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGL 349
Query: 310 SGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTV 369
+GN++F++ G+R NYT++++E+K +G RKIGYW+E DK V T+ +G D S ++N+T
Sbjct: 350 TGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTY 409
Query: 370 VVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDA 429
+VTTILE PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD
Sbjct: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469
Query: 430 DTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 489
DTK WNGMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF
Sbjct: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529
Query: 490 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFN 549
SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+ +S+ +NEFGIFN
Sbjct: 530 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFN 589
Query: 550 SLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 609
SLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES
Sbjct: 590 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 649
Query: 610 AEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRK 669
AEDL+KQTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRK
Sbjct: 650 AEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRK 709
Query: 670 SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSE 729
SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR PVNLAVLKLSE
Sbjct: 710 SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSE 769
Query: 730 QGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC 789
QGVLDKLK+KWWYDKGECG+KDSGSK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFC
Sbjct: 770 QGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFC 829
Query: 790 YKSRAEAKRMK 800
YKSR+E+KRMK
Sbjct: 830 YKSRSESKRMK 840
>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
sapiens]
Length = 906
Score = 1217 bits (3149), Expect = 0.0
Identities = 582/791 (73%), Positives = 693/791 (87%), Gaps = 4/791 (0%)
Query: 10 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSF 69
+L P ID + +++SF +T FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSF
Sbjct: 54 KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSF 113
Query: 70 PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVT 129
P D ++ FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVT
Sbjct: 114 PVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVT 173
Query: 130 AINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYI 189
A+N+ +E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+ GYHYI
Sbjct: 174 AVNILTTT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYI 229
Query: 190 IANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYT 249
+ANLGF D DL K + GANV+GFQ+V+Y D++ +K +++W + +++ KYT
Sbjct: 230 LANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYT 289
Query: 250 SALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGL 309
SALTYD V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL
Sbjct: 290 SALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGL 349
Query: 310 SGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTV 369
+GN++F++ G+R NYT++++E+K +G RKIGYW+E DK V T+ +G D S ++N+T
Sbjct: 350 TGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTY 409
Query: 370 VVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDA 429
+VTTILE PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD
Sbjct: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469
Query: 430 DTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 489
DTK WNGMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF
Sbjct: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529
Query: 490 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFN 549
SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+ +S+ +NEFGIFN
Sbjct: 530 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFN 589
Query: 550 SLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 609
SLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES
Sbjct: 590 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 649
Query: 610 AEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRK 669
AEDL+KQTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRK
Sbjct: 650 AEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRK 709
Query: 670 SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSE 729
SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR PVNLAVLKL+E
Sbjct: 710 SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNE 769
Query: 730 QGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC 789
QG+LDKLKNKWWYDKGECG+ SK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFC
Sbjct: 770 QGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFC 829
Query: 790 YKSRAEAKRMK 800
YKSR+E+KRMK
Sbjct: 830 YKSRSESKRMK 840
>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
precursor [Homo sapiens]
Length = 908
Score = 609 bits (1571), Expect = e-174
Identities = 334/805 (41%), Positives = 487/805 (60%), Gaps = 41/805 (5%)
Query: 11 LTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP 70
LT + + +SF + C Q S GV AIFG S N + S C L V I +
Sbjct: 76 LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWK 135
Query: 71 ---TDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
+D F + + PD L A+L L+++++W +YD GL LQ ++ + +
Sbjct: 136 HQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRY 195
Query: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
+ + + + D KD + L ++++ KE VI DC + I+ Q + +G +
Sbjct: 196 NLR---LKIRQLPADTKDA--KPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTE 250
Query: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP----- 239
YHYI L D+ ++ G N++GF+I++ +++ VS IE+WS +E + P
Sbjct: 251 YYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWS-MERLQAPPKPDS 309
Query: 240 GAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIER 299
G + +AL YDAV V++ A + + + + N PW G
Sbjct: 310 GLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFGTRFMS 361
Query: 300 ALKQVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG 358
+K+ EGL+G I F++ NG R ++ ++++ LK G KIG W + +TE G
Sbjct: 362 LIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGL--NMTESQKG 419
Query: 359 ---NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYK 415
N T L N++++VTTILE PYV+ KK+ + L GN+R+EGYC+DL E++ GF Y+
Sbjct: 420 KPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYE 479
Query: 416 LTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGIS 475
+ +V DGKYGA+D WNGMV EL+ KAD+A+APL IT VRE+VIDFSKPFM+LGIS
Sbjct: 480 IRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGIS 539
Query: 476 IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRE 535
I+ +KP + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+
Sbjct: 540 ILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPH---PCN 596
Query: 536 TQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLA 595
S N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLA
Sbjct: 597 PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLA 656
Query: 596 AFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSV 655
AFLTVERM SPI+SA+DL+KQT+I YG ++ G+T FF++SKI+ +DKMW +M S SV
Sbjct: 657 AFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSV 716
Query: 656 FVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSS 715
V++ EG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS
Sbjct: 717 LVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSP 773
Query: 716 LRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVG 775
R + +A+L+L E+G L +K KWW G C ++S ++ SAL + N+ G+F +L
Sbjct: 774 YRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAA 829
Query: 776 GLGLAMLVALIEFCYKSRAEAKRMK 800
GL L++ VA+ EF YKS+ A+ K
Sbjct: 830 GLVLSVFVAVGEFLYKSKKNAQLEK 854
>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
precursor [Homo sapiens]
Length = 869
Score = 609 bits (1571), Expect = e-174
Identities = 334/805 (41%), Positives = 487/805 (60%), Gaps = 41/805 (5%)
Query: 11 LTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP 70
LT + + +SF + C Q S GV AIFG S N + S C L V I +
Sbjct: 76 LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWK 135
Query: 71 ---TDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
+D F + + PD L A+L L+++++W +YD GL LQ ++ + +
Sbjct: 136 HQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRY 195
Query: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
+ + + + D KD + L ++++ KE VI DC + I+ Q + +G +
Sbjct: 196 NLR---LKIRQLPADTKDA--KPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTE 250
Query: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP----- 239
YHYI L D+ ++ G N++GF+I++ +++ VS IE+WS +E + P
Sbjct: 251 YYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWS-MERLQAPPKPDS 309
Query: 240 GAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIER 299
G + +AL YDAV V++ A + + + + N PW G
Sbjct: 310 GLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFGTRFMS 361
Query: 300 ALKQVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG 358
+K+ EGL+G I F++ NG R ++ ++++ LK G KIG W + +TE G
Sbjct: 362 LIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGL--NMTESQKG 419
Query: 359 ---NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYK 415
N T L N++++VTTILE PYV+ KK+ + L GN+R+EGYC+DL E++ GF Y+
Sbjct: 420 KPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYE 479
Query: 416 LTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGIS 475
+ +V DGKYGA+D WNGMV EL+ KAD+A+APL IT VRE+VIDFSKPFM+LGIS
Sbjct: 480 IRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGIS 539
Query: 476 IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRE 535
I+ +KP + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+
Sbjct: 540 ILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPH---PCN 596
Query: 536 TQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLA 595
S N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLA
Sbjct: 597 PDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLA 656
Query: 596 AFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSV 655
AFLTVERM SPI+SA+DL+KQT+I YG ++ G+T FF++SKI+ +DKMW +M S SV
Sbjct: 657 AFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSV 716
Query: 656 FVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSS 715
V++ EG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS
Sbjct: 717 LVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSP 773
Query: 716 LRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVG 775
R + +A+L+L E+G L +K KWW G C ++S ++ SAL + N+ G+F +L
Sbjct: 774 YRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAA 829
Query: 776 GLGLAMLVALIEFCYKSRAEAKRMK 800
GL L++ VA+ EF YKS+ A+ K
Sbjct: 830 GLVLSVFVAVGEFLYKSKKNAQLEK 854
>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
[Homo sapiens]
Length = 919
Score = 594 bits (1532), Expect = e-170
Identities = 329/803 (40%), Positives = 484/803 (60%), Gaps = 43/803 (5%)
Query: 11 LTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL---HVSFITP 67
LT I + +SF T C Q + GV AIFG N + S C L H+
Sbjct: 79 LTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWK 138
Query: 68 SFPTDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
P D F + + PD L A+L L++Y +W +YD GL LQ ++ A
Sbjct: 139 HHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELI--MAPS 196
Query: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
++ + + + + D D R L ++++ +E R+I DC I+ Q + +G +
Sbjct: 197 RYNIR-LKIRQLPIDSDDS--RPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTE 253
Query: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP----G 240
YH+I L DL ++ G N++GF+I++ D+ VS +E+WS + P G
Sbjct: 254 YYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSESG 313
Query: 241 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 300
+ +AL YDAV +++ ++ + + N+ C + A W G
Sbjct: 314 LLDGVMMTDAALLYDAVHIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMNF 365
Query: 301 LKQVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG- 358
+K+ Q EGL+G I F++ +G R ++ ++I+ LK +G K+G WS D + +TE+ G
Sbjct: 366 IKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGL--NITEVAKGR 423
Query: 359 --NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL 416
N T L N++++VTT+LE P+VM +K+ L GN+R+EGYC+DL E+A GF Y++
Sbjct: 424 GPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEI 483
Query: 417 TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISI 476
+V DGKYGA+D D WNGMV EL+ KAD+A+APLTIT VRE+ IDFSKPFM+LG+SI
Sbjct: 484 RLVEDGKYGAQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSI 542
Query: 477 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH-TEEFEDGRE 535
+ +KP + P VFSFL+PL+ +IWM ++ AY+GVS VLF+++RFSPYEW+ G E
Sbjct: 543 LYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSE 602
Query: 536 TQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLA 595
N F + NS WF +G+ M+QG ++ P++LS RI+GG+WWFFTLIIISSYTANLA
Sbjct: 603 VVE----NNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLA 658
Query: 596 AFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSV 655
AFLTVERM SPI+SA+DL+KQT+I YG + G+T FF++SKI+ F+KMW +M S++PS
Sbjct: 659 AFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSA 717
Query: 656 FVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSS 715
V+ EG+ R + YA L+EST EY+ QR C+ ++GG +DSKGYGI TP GS
Sbjct: 718 LVKNNEEGIQRALTA--DYALLMESTTIEYVTQRN-CNLTQIGGLIDSKGYGIGTPMGSP 774
Query: 716 LRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVG 775
R + +A+L+L E+ L +K KWW G C +++ ++ SAL + + G+F +L
Sbjct: 775 YRDKITIAILQLQEEDKLHIMKEKWWRGSG-CPEEEN---KEASALGIQKIGGIFIVLAA 830
Query: 776 GLGLAMLVALIEFCYKSRAEAKR 798
GL L++LVA+ EF YK R A+R
Sbjct: 831 GLVLSVLVAVGEFVYKLRKTAER 853
>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
precursor [Homo sapiens]
Length = 905
Score = 592 bits (1525), Expect = e-169
Identities = 330/799 (41%), Positives = 483/799 (60%), Gaps = 44/799 (5%)
Query: 11 LTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP 70
LT I + + +SF + C Q + GV A+FG SV+ + S C L V P
Sbjct: 77 LTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEV----PHIQ 132
Query: 71 TDGTHP-------FVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120
T HP F I + PD + A+L L+ YY W +Y+ GL LQ ++ +
Sbjct: 133 TRWKHPSVDNKDLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKA 192
Query: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180
+ ++ + + N D K L ++++ KE VI DC + +I+ Q++ +G
Sbjct: 193 PSRYNIKIKIRQLPSGNKDAKP-----LLKEMKKGKEFYVIFDCSHETAAEILKQILFMG 247
Query: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240
+ YHY L DL ++ G N++GF++++ D+ VS IE+WS + P
Sbjct: 248 MMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPR 307
Query: 241 AHTTTIK----YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVE 296
T + +AL YDAV ++ A + R ++ +S + PW G
Sbjct: 308 PETGLLDGMMTTEAALMYDAVYMV--AIASHRASQLTVS------SLQCHRHKPWRLGPR 359
Query: 297 IERALKQVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTEL 355
+K+ + +GL+G+I F++ NG R ++ ++I+ LK G KIG W+ + +T +
Sbjct: 360 FMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNK 419
Query: 356 P-SGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKY 414
S N T L N+T++VTTILE PYVM +K+ + L GN+R+EGYC+DL E++ GF Y
Sbjct: 420 DKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIY 479
Query: 415 KLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGI 474
+ +V DGKYGA++ D WNGMV EL+ +AD+A+APLTIT VRE+VIDFSKPFM+LGI
Sbjct: 480 DVKLVPDGKYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGI 538
Query: 475 SIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGR 534
SI+ +KP + PGVFSFL+PL+ +IWM ++ A +GVS VLF+++RF+PYEW+
Sbjct: 539 SILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPH---PC 595
Query: 535 ETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANL 594
S N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANL
Sbjct: 596 NPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANL 655
Query: 595 AAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPS 654
AAFLTVERM SPI+SA+DL+KQT+I YG + GST FF++SKI+ ++KMW +M S + +
Sbjct: 656 AAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQT 715
Query: 655 VFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS 714
VR + EG+ RV + YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS
Sbjct: 716 ALVRNSDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGS 772
Query: 715 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILV 774
R + +A+L+L E+G L +K KWW G C +D+ ++ SAL + N+ G+F +L
Sbjct: 773 PYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEDN---KEASALGVENIGGIFIVLA 828
Query: 775 GGLGLAMLVALIEFCYKSR 793
GL L++ VA+ EF YKSR
Sbjct: 829 AGLVLSVFVAIGEFIYKSR 847
>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
precursor [Homo sapiens]
Length = 918
Score = 582 bits (1501), Expect = e-166
Identities = 330/814 (40%), Positives = 484/814 (59%), Gaps = 59/814 (7%)
Query: 11 LTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP 70
LT I + + +SF + C Q + GV A+FG SV+ + S C L V P
Sbjct: 77 LTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEV----PHIQ 132
Query: 71 TDGTHP-------FVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120
T HP F I + PD + A+L L+ YY W +Y+ GL LQ ++ +
Sbjct: 133 TRWKHPSVDNKDLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKA 192
Query: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180
+ ++ + + N D K L ++++ KE VI DC + +I+ Q++ +G
Sbjct: 193 PSRYNIKIKIRQLPSGNKDAKP-----LLKEMKKGKEFYVIFDCSHETAAEILKQILFMG 247
Query: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240
+ YHY L DL ++ G N++GF++++ D+ VS IE+WS + P
Sbjct: 248 MMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPR 307
Query: 241 AHTTTIK----YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVE 296
T + +AL YDAV ++ A + R ++ +S + PW G
Sbjct: 308 PETGLLDGMMTTEAALMYDAVYMV--AIASHRASQLTVS------SLQCHRHKPWRLGPR 359
Query: 297 IERALKQVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGP---------------RKIG 340
+K+ + +GL+G+I F++ NG R ++ ++I+ LK G +KIG
Sbjct: 360 FMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIG 419
Query: 341 YWSEVDKMVVTLTELP-SGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYC 399
W+ + +T + S N T L N+T++VTTILE PYVM +K+ + L GN+R+EGYC
Sbjct: 420 IWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYC 479
Query: 400 VDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVR 459
+DL E++ GF Y + +V DGKYGA++ D WNGMV EL+ +AD+A+APLTIT VR
Sbjct: 480 LDLLKELSNILGFIYDVKLVPDGKYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVR 538
Query: 460 EEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSR 519
E+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+ +IWM ++ A +GVS VLF+++R
Sbjct: 539 EKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIAR 598
Query: 520 FSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVW 579
F+PYEW+ S N F + NS WF +GA M+QG ++ P++LS RIVGG+W
Sbjct: 599 FTPYEWYNPH---PCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIW 655
Query: 580 WFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIA 639
WFFTLIIISSYTANLAAFLTVERM SPI+SA+DL+KQT+I YG + GST FF++SKI+
Sbjct: 656 WFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIS 715
Query: 640 VFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG 699
++KMW +M S + + VR + EG+ RV + YA L+EST EY+ QR C+ ++GG
Sbjct: 716 TYEKMWAFMSSRQQTALVRNSDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGG 772
Query: 700 NLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTS 759
+DSKGYG+ TP GS R + +A+L+L E+G L +K KWW G C +D+ ++ S
Sbjct: 773 LIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEDN---KEAS 828
Query: 760 ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 793
AL + N+ G+F +L GL L++ VA+ EF YKSR
Sbjct: 829 ALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSR 862
>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
Length = 956
Score = 509 bits (1312), Expect = e-144
Identities = 301/796 (37%), Positives = 449/796 (56%), Gaps = 41/796 (5%)
Query: 22 NSFAVTNAFCSQFSRGVYAIFG-FYDKKSVNTITSFCGTLHV-----------SFITPSF 69
+ + C +GV A+ G S + I++ CG V F F
Sbjct: 75 SEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVKFQFQRF 134
Query: 70 PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVT 129
T HP D+ A+ ++ ++ + L L+ +L K ++
Sbjct: 135 TTLNLHP----SNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLS 190
Query: 130 AINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYI 189
+ +D +D L +++ K +I+ + I+ + +G Y YI
Sbjct: 191 V----RMLDDTRDPT--PLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYI 244
Query: 190 IANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYT 249
NL F+ + + N+ GF I + + +F + + ++ T +
Sbjct: 245 FTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTGPALS 304
Query: 250 SALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 308
SAL +DAV + A + L R Q I + A W G + L+ V++EG
Sbjct: 305 SALLFDAVYAVVTAVQELNRSQEIGVKPLS------CGSAQIWQHGTSLMNYLRMVELEG 358
Query: 309 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 368
L+G+I+F+ G+R NY + I++ NG R+IG W + + + + L + N + L N T
Sbjct: 359 LTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMD-SHLYASNISDTLFNTT 417
Query: 369 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 428
+VVTTILE+PY+M+K NH+ +EGN+RYEG+CVD+ E+A+ F YK+ +VGDG YG +
Sbjct: 418 LVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPE 477
Query: 429 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 488
A+ W GMVGEL+ KAD+A+A LTIT RE+VIDFSKPFM+LGISI+ + KPG
Sbjct: 478 ANGT-WTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGY 536
Query: 489 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIF 548
FSFLDP + +W+ ++ AY+ VS VLFLV+R +PYEW++ + + + N++ +
Sbjct: 537 FSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPH--PCAQGRCNLLVNQYSLG 594
Query: 549 NSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 608
NSLWF +G FM+QG I+PR+LS R V GVWW FTLIIISSYTANLAAFLTV+RM PIE
Sbjct: 595 NSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIE 654
Query: 609 SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVR 668
S +DL+ QT I YGT+ GS+ FF+ S+ + +MW YM S +PSVFV++T EG+ARV
Sbjct: 655 SVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVL 714
Query: 669 KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLS 728
S YA+LLESTMNEY QR C+ ++GG LD+KGYGI P GS R +LA+L+L
Sbjct: 715 NS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQ 771
Query: 729 EQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 788
E L+ LK KWW + G+C ++ + L + N+ G+F +L+ GL +A+ +A++EF
Sbjct: 772 ENNRLEILKRKWW-EGGKCPKEED---HRAKGLGMENIGGIFVVLICGLIVAIFMAMLEF 827
Query: 789 CYKSR-AEAKRMKVAK 803
+ R +EA + V +
Sbjct: 828 LWTLRHSEATEVSVCQ 843
>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
Length = 980
Score = 507 bits (1306), Expect = e-143
Identities = 300/805 (37%), Positives = 454/805 (56%), Gaps = 38/805 (4%)
Query: 10 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFG-FYDKKSVNTITSFCGTLHVSFI--- 65
R+ I L+ + + T+ C +GV ++ G S +T++ CG + I
Sbjct: 62 RVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVG 121
Query: 66 ---TPS-----FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAV 117
TP F + +P D+ A+ +++ + + + + L L+ +
Sbjct: 122 PEETPRLQYLRFASVSLYP----SNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEEL 177
Query: 118 LDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVI 177
+ K ++ + +D +D L +++ K +I+D + I+ +
Sbjct: 178 VRGFLISKETLSV----RMLDDSRDPT--PLLKEIRDDKVSTIIIDANASISHLILRKAS 231
Query: 178 TIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKE 237
+G Y YI+ + F L I +N+ GF + + +F+ + +
Sbjct: 232 ELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWREN 291
Query: 238 YPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEI 297
+ ++AL +DAV V+ A R L + + EI + A A W G +
Sbjct: 292 CEASTYLGPALSAALMFDAVHVVVSAVRELNRSQ-EIGVKPLA----CTSANIWPHGTSL 346
Query: 298 ERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPS 357
L+ V+ +GL+G ++F+ G+R NYT+ I+E G R+IG W + + T L
Sbjct: 347 MNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDI 406
Query: 358 GNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLT 417
N + L NKT+VVTTILE+PYVM + N + L GNER+EG+CVD+ E+A+ F+Y+L
Sbjct: 407 -NLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLR 465
Query: 418 IVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIM 477
+V DG YGA + + W GMVGEL+ KAD+A+A TIT RE+VIDFSKPFM+LGISI+
Sbjct: 466 LVEDGLYGAPEPNGS-WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISIL 524
Query: 478 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQ 537
+ KPG FSFLDP + +W+ ++ AY+ VS VLFL +R SPYEW+ +
Sbjct: 525 YRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPH--PCLRAR 582
Query: 538 SSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 597
N++ + NSLWF +G FM+QG +I PR+LS R V GVWW FTLIIISSYTANLAAF
Sbjct: 583 PHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAF 642
Query: 598 LTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFV 657
LTV+RM P+ESA+DL+ QT I YGT+ +GST FF+ S+ + +MW YM+S +PSVFV
Sbjct: 643 LTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFV 702
Query: 658 RTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR 717
++T EG+ARV S +YA+LLESTMNEY +R C+ ++GG LD+KGYGI P GS R
Sbjct: 703 KSTEEGIARVLNS--RYAFLLESTMNEY-HRRLNCNLTQIGGLLDTKGYGIGMPLGSPFR 759
Query: 718 TPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGL 777
+ LA+L+L E L+ LK KWW + G C ++ + L + N+ G+F +L+ GL
Sbjct: 760 DEITLAILQLQENNRLEILKRKWW-EGGRCPKEED---HRAKGLGMENIGGIFIVLICGL 815
Query: 778 GLAMLVALIEFCYKSRAEAKRMKVA 802
+A+ VA++EF + +R A+ +V+
Sbjct: 816 IIAVFVAVMEFIWSTRRSAESEEVS 840
>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 477 bits (1228), Expect = e-134
Identities = 214/371 (57%), Positives = 299/371 (80%), Gaps = 5/371 (1%)
Query: 5 STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64
S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S
Sbjct: 58 SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
Query: 65 ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
ITPSFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +
Sbjct: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
Query: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
W V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
Query: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244
GYHYIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T
Sbjct: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
Query: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304
KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
Query: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364
+++GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +
Sbjct: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
Query: 365 ENKTVVVTTIL 375
EN+TVVVTTI+
Sbjct: 413 ENRTVVVTTIM 423
>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 477 bits (1228), Expect = e-134
Identities = 214/371 (57%), Positives = 299/371 (80%), Gaps = 5/371 (1%)
Query: 5 STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64
S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S
Sbjct: 58 SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
Query: 65 ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
ITPSFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +
Sbjct: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
Query: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
W V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
Query: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244
GYHYIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T
Sbjct: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
Query: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304
KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
Query: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364
+++GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +
Sbjct: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
Query: 365 ENKTVVVTTIL 375
EN+TVVVTTI+
Sbjct: 413 ENRTVVVTTIM 423
>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
sapiens]
Length = 1009
Score = 343 bits (881), Expect = 3e-94
Identities = 249/824 (30%), Positives = 404/824 (49%), Gaps = 66/824 (8%)
Query: 10 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFI---- 65
++T I +E N F C ++G+ A+ S N + S +H+ +
Sbjct: 59 KITYSIKVIEANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQR 118
Query: 66 ----TPSF-----PTDGTHPFVIQMRPD--LKGALLSLIEYYQWDKFAYLYDSDRGLSTL 114
+P P+ + + RP L +L L+ +W KF YDS+ + L
Sbjct: 119 NPGGSPRTACHLNPSPDGEAYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGL 178
Query: 115 QAVLDSAAEKKWQVTAINVG-NINNDKKDEMYRSLFQDLELKKE-------RRVILDCER 166
Q+ LD A+ V+ V NI++ ++ SLF ++ ++ RR IL
Sbjct: 179 QSFLDQASRLGLDVSLQKVDKNISH-----VFTSLFTTMKTEELNRYRDTLRRAILLLSP 233
Query: 167 DKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFG--GANVSGFQIVDY--DDSL 222
+ +++ + K H++ N +D ++L + G QI D+
Sbjct: 234 QGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKDNQK 293
Query: 223 VSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGD 282
++ R S+L G + ++ ++ YD+V ++ AF + R S +
Sbjct: 294 CTRNNHRISSLLCDPQEG-YLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASL--N 350
Query: 283 CLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIM-----ELKTNGPR 337
C+ PW G + +K+ + GL+G ++F ++ I+ E R
Sbjct: 351 CIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMR 410
Query: 338 KIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEG 397
K+ W + +L E P G+ GL T+ V T+LE P+VM+ +N +L +RY+G
Sbjct: 411 KLATWDSEKGLNGSLQERPMGSRLQGL---TLKVVTVLEEPFVMVAEN--ILGQPKRYKG 465
Query: 398 YCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITL 457
+ +D+ +AK GFKY++ DG+YG + +T WNGM+GEL+ +AD+AI+ +TIT
Sbjct: 466 FSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTS-WNGMIGELISKRADLAISAITITP 524
Query: 458 VREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLV 517
RE V+DFSK +M + I+IKKP++ K +FS P + +W CI A V V++F++
Sbjct: 525 ERESVVDFSKRYMDYSVGILIKKPEE-KISIFSLFAPFDFAVWACIAAAIPVVGVLIFVL 583
Query: 518 SRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGG 577
+R + + + S S + +++W GAF++QG + S S++ RIV G
Sbjct: 584 NRIQAVR-----AQSAAQPRPSASAT---LHSAIWIVYGAFVQQGGESSVNSMAMRIVMG 635
Query: 578 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRR-- 635
WW FTLI+ SSYTANLAAFLTV RM +PI + +DLSKQ E++YGT+ + E+FR
Sbjct: 636 SWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKG 695
Query: 636 ----SKIAVFDKMW-TYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIE-QR 689
+ + F ++W T ++ V + +EG+ + + KG YA+L + + EY
Sbjct: 696 TNPLEQDSTFAELWRTISKNGGADNCVSSPSEGIRKAK--KGNYAFLWDVAVVEYAALTD 753
Query: 690 KPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGA 749
C +G ++ SKGYGIA GS R + +L+L + G LD LK KWW G C
Sbjct: 754 DDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDL 813
Query: 750 KDSGSKEKT-SALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 792
S + +L L + AGVF IL GL LA LVA +E + S
Sbjct: 814 TSHASAQADGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNS 857
>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
Length = 1007
Score = 339 bits (869), Expect = 7e-93
Identities = 234/828 (28%), Positives = 405/828 (48%), Gaps = 75/828 (9%)
Query: 10 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSF 69
++T + ++ N F C ++G+ A+ S ++ S +H+ +
Sbjct: 62 KITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQR 121
Query: 70 PTDGT-------------HPFVIQMRPD--LKGALLSLIEYYQWDKFAYLYDSDRGLSTL 114
T GT + + +RP L +L ++ Y W KF YDS+ + +
Sbjct: 122 STAGTPRSGCGLTRSNRNDDYTLSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGI 181
Query: 115 QAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKE-------RRVILDCERD 167
Q LD +++ V V N N +M +LF + +++ RR IL
Sbjct: 182 QEFLDKVSQQGMDVALQKVENNIN----KMITTLFDTMRIEELNRYRDTLRRAILVMNPA 237
Query: 168 KVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFI 227
+ +V+ H+II N D D+ ++ ++ I+ +
Sbjct: 238 TAKSFITEVVETNLVAFDCHWIIINEEINDVDVQELV--RRSIGRLTIIRQTFPVPQNIS 295
Query: 228 ERW--------STLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGN 279
+R STL + + P A I ++ YD V ++ AF + R S
Sbjct: 296 QRCFRGNHRISSTLCDPKDPFAQNMEI--SNLYIYDTVLLLANAFHKKLEDRKWHSMASL 353
Query: 280 AGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIM-----ELKTN 334
+ C+ + PW G + +K+ V GL+G ++F +NG N I+ E
Sbjct: 354 S--CIRKNSKPWQGGRSMLETIKKGGVSGLTGELEFGENGGNPNVHFEILGTNYGEELGR 411
Query: 335 GPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNER 394
G RK+G W+ V + +LT+ N+ G+ + V T+LE P+VM+ +N +L ++
Sbjct: 412 GVRKLGCWNPVTGLNGSLTDKKLENNMRGV---VLRVVTVLEEPFVMVSEN--VLGKPKK 466
Query: 395 YEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLT 454
Y+G+ +D+ ++ + GF Y++ + D KYG+ D WNG+VGELV+ +ADI I+ LT
Sbjct: 467 YQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGT-WNGLVGELVFKRADIGISALT 525
Query: 455 ITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVL 514
IT RE V+DF+ +M + +++++ +K+ +F+ L P +W CI + V +++
Sbjct: 526 ITPDRENVVDFTTRYMDYSVGVLLRRAEKTVD-MFACLAPFDLSLWACIAGTVLLVGLLV 584
Query: 515 FLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRI 574
+L++ +P + G T ++ ++NS+WF G+F++QG ++ +L+ R+
Sbjct: 585 YLLNWLNP-----PRLQMGSMTSTT-------LYNSMWFVYGSFVQQGGEVPYTTLATRM 632
Query: 575 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFR 634
+ G WW F LI+ISSYTANLAAFLT+ R+ S I+S +DLSKQTEI YGT+ + E R
Sbjct: 633 MMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVR 692
Query: 635 RSKI------AVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSK-GKYAYLLESTMNEYIE 687
+ +++ +MW + + S E A ++K K G YA++ ++ + EY+
Sbjct: 693 MKGLNPFERDSMYSQMWRMINRSNGS--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVA 750
Query: 688 QRKP-CDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGE 746
P C +G + +GYGIA GS R + +L+L + G +D LK+KWW G+
Sbjct: 751 INDPDCSFYTIGNTVADRGYGIALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQ 810
Query: 747 CGAKDS-GSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 793
C S +K+K AL + + AGVF IL G+ L+ +A++E + R
Sbjct: 811 CDLYSSVDTKQKGGALDIKSFAGVFCILAAGIVLSCFIAMLETWWNKR 858
>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
Length = 885
Score = 235 bits (599), Expect = 1e-61
Identities = 181/615 (29%), Positives = 306/615 (49%), Gaps = 85/615 (13%)
Query: 247 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 305
K SA DAV V+ +A L K+ I RG C+ N + W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 306 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 356
+G++G ++F+++G R +IM L+ ++G ++ D+ ++ TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 357 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 391
G S + + TI + P+V +K ++ G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445
Query: 392 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 441
+ R+ G+C+DL ++A+ F Y++ +V DGK+G ++ ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505
Query: 442 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 501
+ G+AD+ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564
Query: 502 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 559
+ + V+V+L+L+ RFSP+ GR +SE E + +++WFS G +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615
Query: 560 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 615
G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D +
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675
Query: 616 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 675
+ Y T+ S +FRR M+ +M + AE + VR +K +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728
Query: 676 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 735
++ +S + E+ E + CD + G G+GI K S + V+L++LK E G ++
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787
Query: 736 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 795
L +K W EC ++ + + L+ N+AGVF ++ GG+ + + IE YK +
Sbjct: 788 L-DKTWVRYQECDSRSNA----PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKD 842
Query: 796 AKR--MKVAKNAQNI 808
A+R M++A A N+
Sbjct: 843 ARRKQMQLAFAAVNV 857
>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
Length = 938
Score = 235 bits (599), Expect = 1e-61
Identities = 181/615 (29%), Positives = 306/615 (49%), Gaps = 85/615 (13%)
Query: 247 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 305
K SA DAV V+ +A L K+ I RG C+ N + W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 306 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 356
+G++G ++F+++G R +IM L+ ++G ++ D+ ++ TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 357 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 391
G S + + TI + P+V +K ++ G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445
Query: 392 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 441
+ R+ G+C+DL ++A+ F Y++ +V DGK+G ++ ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505
Query: 442 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 501
+ G+AD+ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564
Query: 502 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 559
+ + V+V+L+L+ RFSP+ GR +SE E + +++WFS G +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615
Query: 560 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 615
G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D +
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675
Query: 616 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 675
+ Y T+ S +FRR M+ +M + AE + VR +K +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728
Query: 676 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 735
++ +S + E+ E + CD + G G+GI K S + V+L++LK E G ++
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787
Query: 736 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 795
L +K W EC ++ + + L+ N+AGVF ++ GG+ + + IE YK +
Sbjct: 788 L-DKTWVRYQECDSRSNA----PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKD 842
Query: 796 AKR--MKVAKNAQNI 808
A+R M++A A N+
Sbjct: 843 ARRKQMQLAFAAVNV 857
>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
Length = 901
Score = 235 bits (599), Expect = 1e-61
Identities = 181/615 (29%), Positives = 306/615 (49%), Gaps = 85/615 (13%)
Query: 247 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 305
K SA DAV V+ +A L K+ I RG C+ N + W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 306 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 356
+G++G ++F+++G R +IM L+ ++G ++ D+ ++ TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 357 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 391
G S + + TI + P+V +K ++ G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445
Query: 392 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 441
+ R+ G+C+DL ++A+ F Y++ +V DGK+G ++ ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505
Query: 442 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 501
+ G+AD+ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564
Query: 502 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 559
+ + V+V+L+L+ RFSP+ GR +SE E + +++WFS G +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615
Query: 560 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 615
G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D +
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675
Query: 616 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 675
+ Y T+ S +FRR M+ +M + AE + VR +K +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728
Query: 676 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 735
++ +S + E+ E + CD + G G+GI K S + V+L++LK E G ++
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787
Query: 736 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 795
L +K W EC ++ + + L+ N+AGVF ++ GG+ + + IE YK +
Sbjct: 788 L-DKTWVRYQECDSRSNA----PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKD 842
Query: 796 AKR--MKVAKNAQNI 808
A+R M++A A N+
Sbjct: 843 ARRKQMQLAFAAVNV 857
>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
[Homo sapiens]
Length = 1484
Score = 187 bits (475), Expect = 3e-47
Identities = 183/740 (24%), Positives = 329/740 (44%), Gaps = 100/740 (13%)
Query: 89 LLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKK---WQVTAINVGNINNDKKDEMY 145
+L+++E Y W F+ + G + S E W++ + + +++ D D
Sbjct: 157 MLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKI 216
Query: 146 RSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQF 205
++ + L+ ++L C +++ I + ++G GY +I+ +L D D + +F
Sbjct: 217 QNQLKKLQ---SPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPAEF 273
Query: 206 GGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFR 265
+S V YD+ W +Y A D + ++T A
Sbjct: 274 PTGLIS----VSYDE---------W------DYG---------LPARVRDGIAIITTAAS 305
Query: 266 NLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYT 325
++ + I ++ C Q + R L V EG N+ F ++G +++
Sbjct: 306 DMLSEHSFIPEPKSS--CYNTHEKRIYQSNMLNRYLINVTFEGR--NLSFSEDGYQMHPK 361
Query: 326 INIMEL-KTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKK 384
+ I+ L K ++G W + + +T E+ + + T+ E+P+V+++
Sbjct: 362 LVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVES 421
Query: 385 ---------------NHEMLEGNERYE----------GYCVDLAAEIAKHCGFKYKLTIV 419
++ N+ E G+C+D+ +I+K F Y L +V
Sbjct: 422 VDPLSGTCMRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLV 481
Query: 420 GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 479
+GK+G + T WNGM+GE+V +A +A+ LTI R EV+DFS PF+ GIS+M+
Sbjct: 482 TNGKHGKKINGT--WNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVS 539
Query: 480 KPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQS 538
+ +FL+P + ++W M V I +V +F+ FSP ++ DGRE
Sbjct: 540 R-SNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYN-RCLADGREPGG 597
Query: 539 SESTNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 597
F I ++W G + +P+ + +I+ VW FF +I ++SYTANLAAF
Sbjct: 598 P----SFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAF 653
Query: 598 LTVERMVSPIESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSA 651
+ E V + D Q +GT+ +GST+ R + + +M YM
Sbjct: 654 MIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN----YAEMHAYM--- 706
Query: 652 EPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGI 708
F + + K+ A++ ++ + Y+ R + C + +G S GYGI
Sbjct: 707 --GKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGI 764
Query: 709 ATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAG 768
A K S + V+LA+L+L G +++L+ W G C + ++ +S L + N+AG
Sbjct: 765 AIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC--HNEKNEVMSSQLDIDNMAG 820
Query: 769 VFYILVGGLGLAMLVALIEF 788
VFY+ LG AM ++LI F
Sbjct: 821 VFYM----LGAAMALSLITF 836
>gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor
[Homo sapiens]
Length = 1233
Score = 182 bits (462), Expect = 1e-45
Identities = 191/792 (24%), Positives = 335/792 (42%), Gaps = 103/792 (13%)
Query: 35 SRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIE 94
+ V I F ++ I S G V +TP P + + L+ L ++E
Sbjct: 101 TEAVAQILDFISSQTHVPILSISGGSAV-VLTPKEPGSAFLQLGVSLEQQLQ-VLFKVLE 158
Query: 95 YYQWDKFAYLYDSDRG----LSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 150
Y W FA + G L ++AV D A+ W++ + + + L +
Sbjct: 159 EYDWSAFAVITSLHPGHALFLEGVRAVAD-ASHVSWRLLDVVTLELGPGGPRARTQRLLR 217
Query: 151 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 210
L+ + C R++ + + G G+ +++ NL D A
Sbjct: 218 QLDAPV---FVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTD--------APP 266
Query: 211 SGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRK 269
+ F + L+S E W +L +K D V ++ + +
Sbjct: 267 ATFPV-----GLISVVTESWRLSLRQK----------------VRDGVAILALGAHSYWR 305
Query: 270 QRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIM 329
Q + AGDC +P R L V EG + F G + T+ ++
Sbjct: 306 QHGTLP--APAGDCRVHPGPVSPAREAFYRHLLNVTWEGR--DFSFSPGGYLVQPTMVVI 361
Query: 330 ELKTNGP-RKIGYWSE-VDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKK--- 384
L + +G W V M + S + ++++ + V T+ E P+V+++
Sbjct: 362 ALNRHRLWEMVGRWEHGVLYMKYPVWPRYSASLQPVVDSRHLTVATLEERPFVIVESPDP 421
Query: 385 ----------------NHEMLEGNER------YEGYCVDLAAEIAKHCGFKYKLTIVGDG 422
NH G+ +G+C+D+ ++A+ F Y L +V +G
Sbjct: 422 GTGGCVPNTVPCRRQSNHTFSSGDVAPYTKLCCKGFCIDILKKLARVVKFSYDLYLVTNG 481
Query: 423 KYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 482
K+G R +WNGM+GE+ Y +AD+AI LTI R E++DFS PF+ GIS+M+ +
Sbjct: 482 KHGKRVRG--VWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVAR-S 538
Query: 483 KSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSES 541
+FL+P + +W M V V++ +F+ FSP ++ + G+++
Sbjct: 539 NGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYN-QNLTRGKKSGGP-- 595
Query: 542 TNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 600
F I S+W I +PR + +I+ VW FF +I ++SYTANLAAF+
Sbjct: 596 --AFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQ 653
Query: 601 ERMVSPIESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPS 654
E+ + + D Q +GT+ +GST+ R + + M T+M
Sbjct: 654 EQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSN----YRDMHTHMVK---- 705
Query: 655 VFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATP 711
F + + E K A++ ++ + Y+ + + C + +G + GYGIA
Sbjct: 706 -FNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQ 764
Query: 712 KGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFY 771
K S + ++LA+L+ G KL+ W G C ++ ++ +S L + N+AGVFY
Sbjct: 765 KDSHWKRAIDLALLQFLGDGETQKLETVWL--SGIC--QNEKNEVMSSKLDIDNMAGVFY 820
Query: 772 ILVGGLGLAMLV 783
+L+ +GLA+LV
Sbjct: 821 MLLVAMGLALLV 832
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
[Homo sapiens]
Length = 1336
Score = 175 bits (444), Expect = 1e-43
Identities = 121/400 (30%), Positives = 206/400 (51%), Gaps = 34/400 (8%)
Query: 396 EGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTI 455
+G+C+D+ +A GF Y L +V +GK+G + +WNGM+GE+ Y +AD+AI LTI
Sbjct: 485 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDG--VWNGMIGEVFYQRADMAIGSLTI 542
Query: 456 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 514
R E++DFS PF+ GIS+M+ + +FL+P + +W M V V+V +
Sbjct: 543 NEERSEIVDFSVPFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTV 601
Query: 515 FLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGR 573
F+ SP ++ T + F I S+W + +PR + +
Sbjct: 602 FIFEYLSPVGYNR-----SLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSK 656
Query: 574 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQ------TEIAYGTLDSG 627
I+ VW FF +I ++SYTANLAAF+ E V + D Q + +GT+ +G
Sbjct: 657 IMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNG 716
Query: 628 STKEFFRRSKIAVFDKMWTYM-RSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYI 686
ST++ R + + M +YM R +P V E + +++ K A++ ++ + Y+
Sbjct: 717 STEKNIRSN----YPDMHSYMVRYNQPRV-----EEALTQLKAGK-LDAFIYDAAVLNYM 766
Query: 687 EQR-KPCDTMKVGGN--LDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYD 743
++ + C + +G + GYGIA KGS + P++LA+L+ ++ L+ W
Sbjct: 767 ARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWL-- 824
Query: 744 KGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLV 783
G C + + +S L + N+AGVFY+L+ +GL++LV
Sbjct: 825 SGIC--HNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLV 862
>gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2
precursor [Homo sapiens]
Length = 1281
Score = 172 bits (435), Expect = 2e-42
Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)
Query: 142 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 199
D + ++LKK ++L C +D+ I+ + ++G + +I+ +L + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266
Query: 200 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 258
L+ +F SG V YDD W +LE + G T +S L +
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313
Query: 259 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 313
+A + +R E+ + N V W G+ + QV V L+ +
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370
Query: 314 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 369
++++ GK N+T+++ + D +VTL E P D L +T
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429
Query: 370 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 428
V T+ +V + + +E + + +G+C+D+ ++++ F Y L +V +GK+G +
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489
Query: 429 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 488
+WNGM+GE+VY +A +A+ LTI R EV+DFS PF+ GIS+M+ +
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546
Query: 489 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 547
+FL+P + +W M V I ++ +F+ FSP ++ G+ F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601
Query: 548 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 606
++W G + +P+ + +I+ VW FF +I ++SYTANLAAF+ E V
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661
Query: 607 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
+ D Q +GT+ +GST+ R + + M YM +
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709
Query: 661 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 714
+GV A V GK A++ ++ + Y R + C + +G + GYGIA KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769
Query: 715 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILV 774
+ ++LA+L+ G +++L+ W G C + ++ +S L + N+AGVFY+L
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLA 825
Query: 775 GGLGLAMLVALIEFCY 790
+ L+++ + E +
Sbjct: 826 AAMALSLITFIWEHLF 841
>gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 172 bits (435), Expect = 2e-42
Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)
Query: 142 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 199
D + ++LKK ++L C +D+ I+ + ++G + +I+ +L + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266
Query: 200 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 258
L+ +F SG V YDD W +LE + G T +S L +
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313
Query: 259 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 313
+A + +R E+ + N V W G+ + QV V L+ +
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370
Query: 314 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 369
++++ GK N+T+++ + D +VTL E P D L +T
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429
Query: 370 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 428
V T+ +V + + +E + + +G+C+D+ ++++ F Y L +V +GK+G +
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489
Query: 429 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 488
+WNGM+GE+VY +A +A+ LTI R EV+DFS PF+ GIS+M+ +
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546
Query: 489 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 547
+FL+P + +W M V I ++ +F+ FSP ++ G+ F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601
Query: 548 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 606
++W G + +P+ + +I+ VW FF +I ++SYTANLAAF+ E V
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661
Query: 607 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
+ D Q +GT+ +GST+ R + + M YM +
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709
Query: 661 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 714
+GV A V GK A++ ++ + Y R + C + +G + GYGIA KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769
Query: 715 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILV 774
+ ++LA+L+ G +++L+ W G C + ++ +S L + N+AGVFY+L
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLA 825
Query: 775 GGLGLAMLVALIEFCY 790
+ L+++ + E +
Sbjct: 826 AAMALSLITFIWEHLF 841
>gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 172 bits (435), Expect = 2e-42
Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)
Query: 142 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 199
D + ++LKK ++L C +D+ I+ + ++G + +I+ +L + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266
Query: 200 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 258
L+ +F SG V YDD W +LE + G T +S L +
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313
Query: 259 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 313
+A + +R E+ + N V W G+ + QV V L+ +
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370
Query: 314 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 369
++++ GK N+T+++ + D +VTL E P D L +T
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429
Query: 370 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 428
V T+ +V + + +E + + +G+C+D+ ++++ F Y L +V +GK+G +
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489
Query: 429 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 488
+WNGM+GE+VY +A +A+ LTI R EV+DFS PF+ GIS+M+ +
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546
Query: 489 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 547
+FL+P + +W M V I ++ +F+ FSP ++ G+ F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601
Query: 548 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 606
++W G + +P+ + +I+ VW FF +I ++SYTANLAAF+ E V
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661
Query: 607 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
+ D Q +GT+ +GST+ R + + M YM +
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709
Query: 661 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 714
+GV A V GK A++ ++ + Y R + C + +G + GYGIA KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769
Query: 715 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILV 774
+ ++LA+L+ G +++L+ W G C + ++ +S L + N+AGVFY+L
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLA 825
Query: 775 GGLGLAMLVALIEFCY 790
+ L+++ + E +
Sbjct: 826 AAMALSLITFIWEHLF 841
>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
[Homo sapiens]
Length = 1043
Score = 165 bits (417), Expect = 2e-40
Identities = 119/401 (29%), Positives = 197/401 (49%), Gaps = 30/401 (7%)
Query: 397 GYCVDLAAEIAKHCGFKYKLTIVGDGKYGA-RDADTKIWNGMVGELVYGKADIAIAPLTI 455
GYC+DL +A+ F ++L +VGDGKYGA RD W G+VG+L+ G+A +A+ +I
Sbjct: 478 GYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGR---WTGLVGDLLAGRAHMAVTSFSI 534
Query: 456 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 515
R +V+DF+ PF S + IM++ + P + +F+ PL + W +GV L
Sbjct: 535 NSARSQVVDFTSPFFSTSLGIMVRARDTASP-IGAFMWPLHWSTW-------LGVFAALH 586
Query: 516 LVSRF-SPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRI 574
L + F + YEW + R S + N + L F R +P+ +GR+
Sbjct: 587 LTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAIL--FRRTVSSKTPKCPTGRL 644
Query: 575 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS---KQTEIAYGTLDSGSTKE 631
+ +W F L+++SSYTANLAA + ++ + D +GT+ S +
Sbjct: 645 LMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEA 704
Query: 632 FFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKY-AYLLESTMNEY-IEQR 689
+ ++S F M +MR TT GVA + K A++++ ++ +Y +
Sbjct: 705 YIKKS----FPDMHAHMRRHS----APTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSID 756
Query: 690 KPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGA 749
C + VG +GYGI P+ S L + ++ + + G +D L +K WY CG
Sbjct: 757 ADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK-WYKMVPCGK 815
Query: 750 KDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 790
+ E T +S+ + AG+F +L GLG A+L +L E +
Sbjct: 816 RVFAVTE-TLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAF 855
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,334,969
Number of Sequences: 37866
Number of extensions: 1172673
Number of successful extensions: 2849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2658
Number of HSP's gapped (non-prelim): 47
length of query: 836
length of database: 18,247,518
effective HSP length: 111
effective length of query: 725
effective length of database: 14,044,392
effective search space: 10182184200
effective search space used: 10182184200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.