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Search of human proteins with 134304848
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
precursor [Homo sapiens]
(883 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr... 1768 0.0
gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre... 1749 0.0
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H... 1657 0.0
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p... 1370 0.0
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p... 1309 0.0
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p... 1291 0.0
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p... 1290 0.0
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H... 1259 0.0
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H... 1241 0.0
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ... 614 e-175
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ... 614 e-175
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ... 595 e-170
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ... 592 e-169
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p... 583 e-166
gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 514 e-145
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 514 e-145
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens] 510 e-144
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens] 508 e-144
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H... 350 4e-96
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens] 348 1e-95
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens] 236 7e-62
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens] 236 7e-62
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens] 236 7e-62
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ... 186 8e-47
gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [... 182 1e-45
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 171 2e-42
gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2 ... 171 4e-42
gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1 ... 171 4e-42
gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1 pr... 171 4e-42
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate... 163 7e-40
>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
precursor [Homo sapiens]
Length = 883
Score = 1768 bits (4580), Expect = 0.0
Identities = 883/883 (100%), Positives = 883/883 (100%)
Query: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60
MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP
Sbjct: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60
Query: 61 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120
HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG
Sbjct: 61 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120
Query: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180
THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV
Sbjct: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180
Query: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240
GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL
Sbjct: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240
Query: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300
GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT
Sbjct: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300
Query: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360
YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI
Sbjct: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360
Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420
KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT
Sbjct: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420
Query: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480
ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI
Sbjct: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480
Query: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540
WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540
Query: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600
PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF
Sbjct: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600
Query: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660
SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL
Sbjct: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660
Query: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720
SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK
Sbjct: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720
Query: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLL 780
YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLL
Sbjct: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLL 780
Query: 781 DKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
DKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR
Sbjct: 781 DKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
Query: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
precursor [Homo sapiens]
Length = 883
Score = 1749 bits (4530), Expect = 0.0
Identities = 874/883 (98%), Positives = 877/883 (99%)
Query: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60
MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP
Sbjct: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60
Query: 61 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120
HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG
Sbjct: 61 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120
Query: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180
THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV
Sbjct: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180
Query: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240
GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL
Sbjct: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240
Query: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300
GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT
Sbjct: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300
Query: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360
YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI
Sbjct: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360
Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420
KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT
Sbjct: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420
Query: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480
ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI
Sbjct: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480
Query: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540
WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540
Query: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600
PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF
Sbjct: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600
Query: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660
SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL
Sbjct: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660
Query: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720
SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK
Sbjct: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720
Query: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLL 780
YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR VNLAVLKL+EQG+L
Sbjct: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL 780
Query: 781 DKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
DKLKNKWWYDKGECG+ SKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR
Sbjct: 781 DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
Query: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
sapiens]
Length = 836
Score = 1657 bits (4291), Expect = 0.0
Identities = 827/836 (98%), Positives = 830/836 (99%)
Query: 48 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 107
MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL
Sbjct: 1 MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 60
Query: 108 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 167
HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS
Sbjct: 61 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120
Query: 168 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 227
AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG
Sbjct: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180
Query: 228 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 287
KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG
Sbjct: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240
Query: 288 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 347
AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA
Sbjct: 241 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 300
Query: 348 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 407
LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND
Sbjct: 301 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 360
Query: 408 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 467
TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG
Sbjct: 361 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 420
Query: 468 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 527
DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK
Sbjct: 421 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 480
Query: 528 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 587
PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE
Sbjct: 481 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 540
Query: 588 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 647
STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV
Sbjct: 541 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 600
Query: 648 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT
Sbjct: 601 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660
Query: 708 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAV 767
AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR V
Sbjct: 661 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 720
Query: 768 NLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLA 827
NLAVLKL+EQG+LDKLKNKWWYDKGECG+ SKEKTSALSLSNVAGVFYILVGGLGLA
Sbjct: 721 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 780
Query: 828 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 781 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836
>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
precursor [Homo sapiens]
Length = 884
Score = 1370 bits (3546), Expect = 0.0
Identities = 662/889 (74%), Positives = 773/889 (86%), Gaps = 11/889 (1%)
Query: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
Query: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474
TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
Query: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534
DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
Query: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E S + NEFGI
Sbjct: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595
Query: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654
FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655
Query: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714
ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715
Query: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKL 774
RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL NAVNLAVLKL
Sbjct: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKL 775
Query: 775 NEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834
NEQGLLDKLKNKWWYDKGECGSGGGDSK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 776 NEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835
Query: 835 FCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
FCYKSRAEAKRMKVAK+AQ NP+SSQN+QN ATY+EGYNVYG ES+KI
Sbjct: 836 FCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
precursor [Homo sapiens]
Length = 894
Score = 1309 bits (3387), Expect = 0.0
Identities = 638/890 (71%), Positives = 762/890 (85%), Gaps = 12/890 (1%)
Query: 2 QKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE------ 55
Q ++ L L G G N+I IGGLF R QE+SAFR + ++T++
Sbjct: 9 QSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKP 68
Query: 56 FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPS 115
F L H+D+L+ +NSF+VTNAFCSQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPS
Sbjct: 69 FHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPS 128
Query: 116 FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQV 175
FPTD FVIQMRP LKGA+LSL+ +Y+W+KF YLYD++RG S LQA++++A + WQV
Sbjct: 129 FPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQV 188
Query: 176 TAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHY 235
TA +VGNI K + +R + ++++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY
Sbjct: 189 TARSVGNI---KDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHY 245
Query: 236 IIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKY 295
++ANLGFTD L ++ GGAN++GFQIV+ ++ +V +FI+RW L+E+E+P A +KY
Sbjct: 246 MLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 305
Query: 296 TSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 355
TSALT+DA+ V+ EAFR LR+QR+++SRRG+AGDCLANPAVPW QG++IERALK VQV+G
Sbjct: 306 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 365
Query: 356 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 415
++GNI+FD G+R NYTI++ E+K +G RK GYW+E ++ V ++ ND++ EN+T
Sbjct: 366 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFV-PFSDQQISNDSASSENRT 424
Query: 416 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
+VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH KYKL+IVGDGKYGARD
Sbjct: 425 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 484
Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
+TKIWNGMVGELVYG+ADIA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV
Sbjct: 485 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 544
Query: 536 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF-EDGRETQSS-ESTNEFG 593
FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ E+ R+ QS + NEFG
Sbjct: 545 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFG 604
Query: 594 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
IFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP
Sbjct: 605 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 664
Query: 654 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR 713
IESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVAR
Sbjct: 665 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVAR 724
Query: 714 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLK 773
VRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L NAVNLAVLK
Sbjct: 725 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLK 784
Query: 774 LNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI 833
LNEQGLLDKLKNKWWYDKGECGSGGGDSK+KTSALSLSNVAGVFYILVGGLGLAM+VALI
Sbjct: 785 LNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALI 844
Query: 834 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
EFCYKSRAE+KRMK+ KN QN P+ + N+QN+ATY+EGYNVYG ESVKI
Sbjct: 845 EFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894
>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
precursor [Homo sapiens]
Length = 902
Score = 1291 bits (3342), Expect = 0.0
Identities = 625/854 (73%), Positives = 734/854 (85%), Gaps = 11/854 (1%)
Query: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
Query: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474
TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
Query: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534
DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
Query: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E S + NEFGI
Sbjct: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595
Query: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654
FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655
Query: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714
ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715
Query: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKL 774
RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL VNLAVLKL
Sbjct: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKL 775
Query: 775 NEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834
+E G+LDKLKNKWWYDKGECG SK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 776 SEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835
Query: 835 FCYKSRAEAKRMKV 848
FCYKSRAEAKRMK+
Sbjct: 836 FCYKSRAEAKRMKL 849
>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
precursor [Homo sapiens]
Length = 894
Score = 1290 bits (3338), Expect = 0.0
Identities = 629/890 (70%), Positives = 756/890 (84%), Gaps = 12/890 (1%)
Query: 2 QKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE------ 55
Q ++ L L G G N+I IGGLF R QE+SAFR + ++T++
Sbjct: 9 QSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKP 68
Query: 56 FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPS 115
F L H+D+L+ +NSF+VTNAFCSQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPS
Sbjct: 69 FHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPS 128
Query: 116 FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQV 175
FPTD FVIQMRP LKGA+LSL+ +Y+W+KF YLYD++RG S LQA++++A + WQV
Sbjct: 129 FPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQV 188
Query: 176 TAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHY 235
TA +VGNI K + +R + ++++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY
Sbjct: 189 TARSVGNI---KDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHY 245
Query: 236 IIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKY 295
++ANLGFTD L ++ GGAN++GFQIV+ ++ +V +FI+RW L+E+E+P A +KY
Sbjct: 246 MLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 305
Query: 296 TSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 355
TSALT+DA+ V+ EAFR LR+QR+++SRRG+AGDCLANPAVPW QG++IERALK VQV+G
Sbjct: 306 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 365
Query: 356 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 415
++GNI+FD G+R NYTI++ E+K +G RK GYW+E ++ V ++ ND++ EN+T
Sbjct: 366 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFV-PFSDQQISNDSASSENRT 424
Query: 416 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
+VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH KYKL+IVGDGKYGARD
Sbjct: 425 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 484
Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
+TKIWNGMVGELVYG+ADIA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV
Sbjct: 485 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 544
Query: 536 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF-EDGRETQSS-ESTNEFG 593
FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ E+ R+ QS + NEFG
Sbjct: 545 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFG 604
Query: 594 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
IFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP
Sbjct: 605 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 664
Query: 654 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR 713
IESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVAR
Sbjct: 665 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVAR 724
Query: 714 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLK 773
VRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L VNLAVLK
Sbjct: 725 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLK 784
Query: 774 LNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI 833
L+EQG+LDKLKNKWWYDKGECG+ SK+KTSALSLSNVAGVFYILVGGLGLAM+VALI
Sbjct: 785 LSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALI 844
Query: 834 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
EFCYKSRAE+KRMK+ KN QN P+ + N+QN+ATY+EGYNVYG ESVKI
Sbjct: 845 EFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894
>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
sapiens]
Length = 906
Score = 1259 bits (3257), Expect = 0.0
Identities = 609/845 (72%), Positives = 724/845 (85%), Gaps = 6/845 (0%)
Query: 4 IMHISVLLSPVLWGLIFGVS-SNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHI 62
+ HI G + G + N+IQIGGLFP QE++AFR + Q T +L P I
Sbjct: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQI 59
Query: 63 DNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTH 122
D + +++SF +T FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSFP D ++
Sbjct: 60 DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119
Query: 123 PFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGN 182
FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+
Sbjct: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179
Query: 183 INNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGF 242
+E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+ GYHYI+ANLGF
Sbjct: 180 TT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235
Query: 243 TDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYD 302
D DL K + GANV+GFQ+V+Y D++ +K +++W + +++ KYTSALTYD
Sbjct: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 295
Query: 303 AVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKF 362
V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F
Sbjct: 296 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 355
Query: 363 DQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTIL 422
++ G+R NYT++++E+K +G RKIGYW+E DK V T+ +G D S ++N+T +VTTIL
Sbjct: 356 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
Query: 423 ESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWN 482
E PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WN
Sbjct: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475
Query: 483 GMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 542
GMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL
Sbjct: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 535
Query: 543 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSL 602
AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+ +S+ +NEFGIFNSLWFSL
Sbjct: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 595
Query: 603 GAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSK 662
GAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+K
Sbjct: 596 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 655
Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
QTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYA
Sbjct: 656 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 715
Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDK 782
YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LRN VNLAVLKLNEQGLLDK
Sbjct: 716 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDK 775
Query: 783 LKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
LKNKWWYDKGECGSGGGDSK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E
Sbjct: 776 LKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 835
Query: 843 AKRMK 847
+KRMK
Sbjct: 836 SKRMK 840
>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
sapiens]
Length = 906
Score = 1241 bits (3210), Expect = 0.0
Identities = 601/845 (71%), Positives = 719/845 (85%), Gaps = 6/845 (0%)
Query: 4 IMHISVLLSPVLWGLIFGVS-SNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHI 62
+ HI G + G + N+IQIGGLFP QE++AFR + Q T +L P I
Sbjct: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQI 59
Query: 63 DNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTH 122
D + +++SF +T FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSFP D ++
Sbjct: 60 DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119
Query: 123 PFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGN 182
FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+
Sbjct: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179
Query: 183 INNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGF 242
+E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+ GYHYI+ANLGF
Sbjct: 180 TT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235
Query: 243 TDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYD 302
D DL K + GANV+GFQ+V+Y D++ +K +++W + +++ KYTSALTYD
Sbjct: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 295
Query: 303 AVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKF 362
V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F
Sbjct: 296 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 355
Query: 363 DQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTIL 422
++ G+R NYT++++E+K +G RKIGYW+E DK V T+ +G D S ++N+T +VTTIL
Sbjct: 356 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
Query: 423 ESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWN 482
E PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WN
Sbjct: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475
Query: 483 GMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 542
GMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL
Sbjct: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 535
Query: 543 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSL 602
AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+ +S+ +NEFGIFNSLWFSL
Sbjct: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 595
Query: 603 GAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSK 662
GAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+K
Sbjct: 596 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 655
Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
QTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYA
Sbjct: 656 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 715
Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDK 782
YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR VNLAVLKL+EQG+LDK
Sbjct: 716 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDK 775
Query: 783 LKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
LK+KWWYDKGECGS SK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E
Sbjct: 776 LKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 835
Query: 843 AKRMK 847
+KRMK
Sbjct: 836 SKRMK 840
>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
precursor [Homo sapiens]
Length = 908
Score = 614 bits (1583), Expect = e-175
Identities = 345/862 (40%), Positives = 510/862 (59%), Gaps = 50/862 (5%)
Query: 10 LLSPVLWGLIFGVSSNSIQIGGLF------PRGADQEYSAFRVGMVQFSTS---EFRLTP 60
LL +LW +++ ++ GG+F P GA++ F V + + + LT
Sbjct: 19 LLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTY 78
Query: 61 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP--- 117
+ + +SF + C Q S GV AIFG S N + S C L V I +
Sbjct: 79 DTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQV 138
Query: 118 TDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
+D F + + PD L A+L L+++++W +YD GL LQ ++ + + +
Sbjct: 139 SDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLR 198
Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
+ + + D KD + L ++++ KE VI DC + I+ Q + +G + YH
Sbjct: 199 ---LKIRQLPADTKDA--KPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYH 253
Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP-----GAH 289
YI L D+ ++ G N++GF+I++ +++ VS IE+WS +E + P G
Sbjct: 254 YIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWS-MERLQAPPKPDSGLL 312
Query: 290 TTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALK 349
+ +AL YDAV V++ A + + + + N PW G +K
Sbjct: 313 DGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFGTRFMSLIK 364
Query: 350 QVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG--- 405
+ EGL+G I F++ NG R ++ ++++ LK G KIG W + +TE G
Sbjct: 365 EAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGL--NMTESQKGKPA 422
Query: 406 NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTI 465
N T L N++++VTTILE PYV+ KK+ + L GN+R+EGYC+DL E++ GF Y++ +
Sbjct: 423 NITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRL 482
Query: 466 VGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMI 525
V DGKYGA+D WNGMV EL+ KAD+A+APL IT VRE+VIDFSKPFM+LGISI+
Sbjct: 483 VEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILY 542
Query: 526 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQS 585
+KP + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+ S
Sbjct: 543 RKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPH---PCNPDS 599
Query: 586 SESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFL 645
N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFL
Sbjct: 600 DVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFL 659
Query: 646 TVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVR 705
TVERM SPI+SA+DL+KQT+I YG ++ G+T FF++SKI+ +DKMW +M S SV V+
Sbjct: 660 TVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVK 719
Query: 706 TTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRN 765
+ EG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R+
Sbjct: 720 SNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 776
Query: 766 AVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLG 825
+ +A+L+L E+G L +K KWW G C + ++ SAL + N+ G+F +L GL
Sbjct: 777 KITIAILQLQEEGKLHMMKEKWWRGNG-CPE---EESKEASALGVQNIGGIFIVLAAGLV 832
Query: 826 LAMLVALIEFCYKSRAEAKRMK 847
L++ VA+ EF YKS+ A+ K
Sbjct: 833 LSVFVAVGEFLYKSKKNAQLEK 854
>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
precursor [Homo sapiens]
Length = 869
Score = 614 bits (1583), Expect = e-175
Identities = 345/862 (40%), Positives = 510/862 (59%), Gaps = 50/862 (5%)
Query: 10 LLSPVLWGLIFGVSSNSIQIGGLF------PRGADQEYSAFRVGMVQFSTS---EFRLTP 60
LL +LW +++ ++ GG+F P GA++ F V + + + LT
Sbjct: 19 LLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTY 78
Query: 61 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP--- 117
+ + +SF + C Q S GV AIFG S N + S C L V I +
Sbjct: 79 DTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQV 138
Query: 118 TDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
+D F + + PD L A+L L+++++W +YD GL LQ ++ + + +
Sbjct: 139 SDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLR 198
Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
+ + + D KD + L ++++ KE VI DC + I+ Q + +G + YH
Sbjct: 199 ---LKIRQLPADTKDA--KPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYH 253
Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP-----GAH 289
YI L D+ ++ G N++GF+I++ +++ VS IE+WS +E + P G
Sbjct: 254 YIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWS-MERLQAPPKPDSGLL 312
Query: 290 TTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALK 349
+ +AL YDAV V++ A + + + + N PW G +K
Sbjct: 313 DGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFGTRFMSLIK 364
Query: 350 QVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG--- 405
+ EGL+G I F++ NG R ++ ++++ LK G KIG W + +TE G
Sbjct: 365 EAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGL--NMTESQKGKPA 422
Query: 406 NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTI 465
N T L N++++VTTILE PYV+ KK+ + L GN+R+EGYC+DL E++ GF Y++ +
Sbjct: 423 NITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRL 482
Query: 466 VGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMI 525
V DGKYGA+D WNGMV EL+ KAD+A+APL IT VRE+VIDFSKPFM+LGISI+
Sbjct: 483 VEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILY 542
Query: 526 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQS 585
+KP + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+ S
Sbjct: 543 RKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPH---PCNPDS 599
Query: 586 SESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFL 645
N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFL
Sbjct: 600 DVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFL 659
Query: 646 TVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVR 705
TVERM SPI+SA+DL+KQT+I YG ++ G+T FF++SKI+ +DKMW +M S SV V+
Sbjct: 660 TVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVK 719
Query: 706 TTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRN 765
+ EG+ RV S YA+L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R+
Sbjct: 720 SNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 776
Query: 766 AVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLG 825
+ +A+L+L E+G L +K KWW G C + ++ SAL + N+ G+F +L GL
Sbjct: 777 KITIAILQLQEEGKLHMMKEKWWRGNG-CPE---EESKEASALGVQNIGGIFIVLAAGLV 832
Query: 826 LAMLVALIEFCYKSRAEAKRMK 847
L++ VA+ EF YKS+ A+ K
Sbjct: 833 LSVFVAVGEFLYKSKKNAQLEK 854
>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
[Homo sapiens]
Length = 919
Score = 595 bits (1534), Expect = e-170
Identities = 331/804 (41%), Positives = 484/804 (60%), Gaps = 45/804 (5%)
Query: 58 LTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL---HVSFITP 114
LT I + +SF T C Q + GV AIFG N + S C L H+
Sbjct: 79 LTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWK 138
Query: 115 SFPTDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 171
P D F + + PD L A+L L++Y +W +YD GL LQ ++ A
Sbjct: 139 HHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELI--MAPS 196
Query: 172 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 231
++ + + + + D D R L ++++ +E R+I DC I+ Q + +G +
Sbjct: 197 RYNIR-LKIRQLPIDSDDS--RPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTE 253
Query: 232 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP----G 287
YH+I L DL ++ G N++GF+I++ D+ VS +E+WS + P G
Sbjct: 254 YYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSESG 313
Query: 288 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 347
+ +AL YDAV +++ ++ + + N+ C + A W G
Sbjct: 314 LLDGVMMTDAALLYDAVHIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMNF 365
Query: 348 LKQVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG- 405
+K+ Q EGL+G I F++ +G R ++ ++I+ LK +G K+G WS D + +TE+ G
Sbjct: 366 IKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGL--NITEVAKGR 423
Query: 406 --NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL 463
N T L N++++VTT+LE P+VM +K+ L GN+R+EGYC+DL E+A GF Y++
Sbjct: 424 GPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEI 483
Query: 464 TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISI 523
+V DGKYGA+D D WNGMV EL+ KAD+A+APLTIT VRE+ IDFSKPFM+LG+SI
Sbjct: 484 RLVEDGKYGAQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSI 542
Query: 524 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH-TEEFEDGRE 582
+ +KP + P VFSFL+PL+ +IWM ++ AY+GVS VLF+++RFSPYEW+ G E
Sbjct: 543 LYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSE 602
Query: 583 TQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLA 642
N F + NS WF +G+ M+QG ++ P++LS RI+GG+WWFFTLIIISSYTANLA
Sbjct: 603 VVE----NNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLA 658
Query: 643 AFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSV 702
AFLTVERM SPI+SA+DL+KQT+I YG + G+T FF++SKI+ F+KMW +M S++PS
Sbjct: 659 AFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSA 717
Query: 703 FVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSS 762
V+ EG+ R + YA L+EST EY+ QR C+ ++GG +DSKGYGI TP GS
Sbjct: 718 LVKNNEEGIQRALTA--DYALLMESTTIEYVTQRN-CNLTQIGGLIDSKGYGIGTPMGSP 774
Query: 763 LRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEK-TSALSLSNVAGVFYILV 821
R+ + +A+L+L E+ L +K KWW GSG + + K SAL + + G+F +L
Sbjct: 775 YRDKITIAILQLQEEDKLHIMKEKWWR-----GSGCPEEENKEASALGIQKIGGIFIVLA 829
Query: 822 GGLGLAMLVALIEFCYKSRAEAKR 845
GL L++LVA+ EF YK R A+R
Sbjct: 830 AGLVLSVLVAVGEFVYKLRKTAER 853
>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
precursor [Homo sapiens]
Length = 905
Score = 592 bits (1526), Expect = e-169
Identities = 336/839 (40%), Positives = 498/839 (59%), Gaps = 53/839 (6%)
Query: 27 IQIGGLFPRGADQ----EYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAF 77
++IGG+F ++ E AF+ + + + LT I + + +SF +
Sbjct: 37 LRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRA 96
Query: 78 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHP-------FVIQMRP 130
C Q + GV A+FG SV+ + S C L V P T HP F I + P
Sbjct: 97 CDQLALGVAALFGPSHSSSVSAVQSICNALEV----PHIQTRWKHPSVDNKDLFYINLYP 152
Query: 131 D---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDK 187
D + A+L L+ YY W +Y+ GL LQ ++ + + ++ + + N D
Sbjct: 153 DYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA 212
Query: 188 KDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL 247
K L ++++ KE VI DC + +I+ Q++ +G + YHY L DL
Sbjct: 213 KP-----LLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDL 267
Query: 248 LKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK----YTSALTYDA 303
++ G N++GF++++ D+ VS IE+WS + P T + +AL YDA
Sbjct: 268 ELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDA 327
Query: 304 VQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFD 363
V ++ A + R ++ +S + PW G +K+ + +GL+G+I F+
Sbjct: 328 VYMV--AIASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFN 379
Query: 364 Q-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELP-SGNDTSGLENKTVVVTTI 421
+ NG R ++ ++I+ LK G KIG W+ + +T + S N T L N+T++VTTI
Sbjct: 380 KTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTI 439
Query: 422 LESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIW 481
LE PYVM +K+ + L GN+R+EGYC+DL E++ GF Y + +V DGKYGA++ D W
Sbjct: 440 LEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQN-DKGEW 498
Query: 482 NGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDP 541
NGMV EL+ +AD+A+APLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+P
Sbjct: 499 NGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNP 558
Query: 542 LAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFS 601
L+ +IWM ++ A +GVS VLF+++RF+PYEW+ S N F + NS WF
Sbjct: 559 LSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPH---PCNPDSDVVENNFTLLNSFWFG 615
Query: 602 LGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS 661
+GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DL+
Sbjct: 616 VGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLA 675
Query: 662 KQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKY 721
KQT+I YG + GST FF++SKI+ ++KMW +M S + + VR + EG+ RV + Y
Sbjct: 676 KQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTT--DY 733
Query: 722 AYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLD 781
A L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS R+ + +A+L+L E+G L
Sbjct: 734 ALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLH 792
Query: 782 KLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
+K KWW G C + ++ SAL + N+ G+F +L GL L++ VA+ EF YKSR
Sbjct: 793 MMKEKWWRGNG-CPE---EDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSR 847
>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
precursor [Homo sapiens]
Length = 918
Score = 583 bits (1502), Expect = e-166
Identities = 336/854 (39%), Positives = 499/854 (58%), Gaps = 68/854 (7%)
Query: 27 IQIGGLFPRGADQ----EYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAF 77
++IGG+F ++ E AF+ + + + LT I + + +SF +
Sbjct: 37 LRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRA 96
Query: 78 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHP-------FVIQMRP 130
C Q + GV A+FG SV+ + S C L V P T HP F I + P
Sbjct: 97 CDQLALGVAALFGPSHSSSVSAVQSICNALEV----PHIQTRWKHPSVDNKDLFYINLYP 152
Query: 131 D---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDK 187
D + A+L L+ YY W +Y+ GL LQ ++ + + ++ + + N D
Sbjct: 153 DYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA 212
Query: 188 KDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL 247
K L ++++ KE VI DC + +I+ Q++ +G + YHY L DL
Sbjct: 213 KP-----LLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDL 267
Query: 248 LKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK----YTSALTYDA 303
++ G N++GF++++ D+ VS IE+WS + P T + +AL YDA
Sbjct: 268 ELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDA 327
Query: 304 VQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFD 363
V ++ A + R ++ +S + PW G +K+ + +GL+G+I F+
Sbjct: 328 VYMV--AIASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFN 379
Query: 364 Q-NGKRINYTINIMELKTNGP---------------RKIGYWSEVDKMVVTLTELP-SGN 406
+ NG R ++ ++I+ LK G +KIG W+ + +T + S N
Sbjct: 380 KTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSN 439
Query: 407 DTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIV 466
T L N+T++VTTILE PYVM +K+ + L GN+R+EGYC+DL E++ GF Y + +V
Sbjct: 440 ITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLV 499
Query: 467 GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 526
DGKYGA++ D WNGMV EL+ +AD+A+APLTIT VRE+VIDFSKPFM+LGISI+ +
Sbjct: 500 PDGKYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYR 558
Query: 527 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSS 586
KP + PGVFSFL+PL+ +IWM ++ A +GVS VLF+++RF+PYEW+ S
Sbjct: 559 KPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPH---PCNPDSD 615
Query: 587 ESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 646
N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLT
Sbjct: 616 VVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLT 675
Query: 647 VERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRT 706
VERM SPI+SA+DL+KQT+I YG + GST FF++SKI+ ++KMW +M S + + VR
Sbjct: 676 VERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRN 735
Query: 707 TAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNA 766
+ EG+ RV + YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS R+
Sbjct: 736 SDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDK 792
Query: 767 VNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGL 826
+ +A+L+L E+G L +K KWW G C + ++ SAL + N+ G+F +L GL L
Sbjct: 793 ITIAILQLQEEGKLHMMKEKWWRGNG-CPE---EDNKEASALGVENIGGIFIVLAAGLVL 848
Query: 827 AMLVALIEFCYKSR 840
++ VA+ EF YKSR
Sbjct: 849 SVFVAIGEFIYKSR 862
>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 514 bits (1325), Expect = e-145
Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)
Query: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
Query: 415 TVVVTTIL 422
TVVVTTI+
Sbjct: 416 TVVVTTIM 423
>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 514 bits (1325), Expect = e-145
Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)
Query: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
Query: 415 TVVVTTIL 422
TVVVTTI+
Sbjct: 416 TVVVTTIM 423
>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
Length = 956
Score = 510 bits (1314), Expect = e-144
Identities = 301/796 (37%), Positives = 449/796 (56%), Gaps = 41/796 (5%)
Query: 69 NSFAVTNAFCSQFSRGVYAIFG-FYDKKSVNTITSFCGTLHV-----------SFITPSF 116
+ + C +GV A+ G S + I++ CG V F F
Sbjct: 75 SEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVKFQFQRF 134
Query: 117 PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVT 176
T HP D+ A+ ++ ++ + L L+ +L K ++
Sbjct: 135 TTLNLHP----SNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLS 190
Query: 177 AINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYI 236
+ +D +D L +++ K +I+ + I+ + +G Y YI
Sbjct: 191 V----RMLDDTRDPT--PLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYI 244
Query: 237 IANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYT 296
NL F+ + + N+ GF I + + +F + + ++ T +
Sbjct: 245 FTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTGPALS 304
Query: 297 SALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 355
SAL +DAV + A + L R Q I + A W G + L+ V++EG
Sbjct: 305 SALLFDAVYAVVTAVQELNRSQEIGVKPLS------CGSAQIWQHGTSLMNYLRMVELEG 358
Query: 356 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 415
L+G+I+F+ G+R NY + I++ NG R+IG W + + + + L + N + L N T
Sbjct: 359 LTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMD-SHLYASNISDTLFNTT 417
Query: 416 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
+VVTTILE+PY+M+K NH+ +EGN+RYEG+CVD+ E+A+ F YK+ +VGDG YG +
Sbjct: 418 LVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPE 477
Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
A+ W GMVGEL+ KAD+A+A LTIT RE+VIDFSKPFM+LGISI+ + KPG
Sbjct: 478 ANGT-WTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGY 536
Query: 536 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIF 595
FSFLDP + +W+ ++ AY+ VS VLFLV+R +PYEW++ + + + N++ +
Sbjct: 537 FSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPH--PCAQGRCNLLVNQYSLG 594
Query: 596 NSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 655
NSLWF +G FM+QG I+PR+LS R V GVWW FTLIIISSYTANLAAFLTV+RM PIE
Sbjct: 595 NSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIE 654
Query: 656 SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVR 715
S +DL+ QT I YGT+ GS+ FF+ S+ + +MW YM S +PSVFV++T EG+ARV
Sbjct: 655 SVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVL 714
Query: 716 KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLN 775
S YA+LLESTMNEY QR C+ ++GG LD+KGYGI P GS R+ +LA+L+L
Sbjct: 715 NS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQ 771
Query: 776 EQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 835
E L+ LK KWW + G+C + + L + N+ G+F +L+ GL +A+ +A++EF
Sbjct: 772 ENNRLEILKRKWW-EGGKCPK---EEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEF 827
Query: 836 CYKSR-AEAKRMKVAK 850
+ R +EA + V +
Sbjct: 828 LWTLRHSEATEVSVCQ 843
>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
Length = 980
Score = 508 bits (1308), Expect = e-144
Identities = 300/805 (37%), Positives = 454/805 (56%), Gaps = 38/805 (4%)
Query: 57 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFG-FYDKKSVNTITSFCGTLHVSFI--- 112
R+ I L+ + + T+ C +GV ++ G S +T++ CG + I
Sbjct: 62 RVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVG 121
Query: 113 ---TPS-----FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAV 164
TP F + +P D+ A+ +++ + + + + L L+ +
Sbjct: 122 PEETPRLQYLRFASVSLYP----SNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEEL 177
Query: 165 LDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVI 224
+ K ++ + +D +D L +++ K +I+D + I+ +
Sbjct: 178 VRGFLISKETLSV----RMLDDSRDPT--PLLKEIRDDKVSTIIIDANASISHLILRKAS 231
Query: 225 TIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKE 284
+G Y YI+ + F L I +N+ GF + + +F+ + +
Sbjct: 232 ELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWREN 291
Query: 285 YPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEI 344
+ ++AL +DAV V+ A R L + + EI + A A W G +
Sbjct: 292 CEASTYLGPALSAALMFDAVHVVVSAVRELNRSQ-EIGVKPLA----CTSANIWPHGTSL 346
Query: 345 ERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPS 404
L+ V+ +GL+G ++F+ G+R NYT+ I+E G R+IG W + + T L
Sbjct: 347 MNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDI 406
Query: 405 GNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLT 464
N + L NKT+VVTTILE+PYVM + N + L GNER+EG+CVD+ E+A+ F+Y+L
Sbjct: 407 -NLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLR 465
Query: 465 IVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIM 524
+V DG YGA + + W GMVGEL+ KAD+A+A TIT RE+VIDFSKPFM+LGISI+
Sbjct: 466 LVEDGLYGAPEPNGS-WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISIL 524
Query: 525 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQ 584
+ KPG FSFLDP + +W+ ++ AY+ VS VLFL +R SPYEW+ +
Sbjct: 525 YRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPH--PCLRAR 582
Query: 585 SSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 644
N++ + NSLWF +G FM+QG +I PR+LS R V GVWW FTLIIISSYTANLAAF
Sbjct: 583 PHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAF 642
Query: 645 LTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFV 704
LTV+RM P+ESA+DL+ QT I YGT+ +GST FF+ S+ + +MW YM+S +PSVFV
Sbjct: 643 LTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFV 702
Query: 705 RTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR 764
++T EG+ARV S +YA+LLESTMNEY +R C+ ++GG LD+KGYGI P GS R
Sbjct: 703 KSTEEGIARVLNS--RYAFLLESTMNEY-HRRLNCNLTQIGGLLDTKGYGIGMPLGSPFR 759
Query: 765 NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGL 824
+ + LA+L+L E L+ LK KWW + G C + + L + N+ G+F +L+ GL
Sbjct: 760 DEITLAILQLQENNRLEILKRKWW-EGGRCPK---EEDHRAKGLGMENIGGIFIVLICGL 815
Query: 825 GLAMLVALIEFCYKSRAEAKRMKVA 849
+A+ VA++EF + +R A+ +V+
Sbjct: 816 IIAVFVAVMEFIWSTRRSAESEEVS 840
>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
sapiens]
Length = 1009
Score = 350 bits (897), Expect = 4e-96
Identities = 255/859 (29%), Positives = 421/859 (49%), Gaps = 71/859 (8%)
Query: 27 IQIGGLFPRGADQEYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAFCSQF 81
I IG +F A ++ F++ + S ++ ++T I +E N F C
Sbjct: 24 IHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLM 83
Query: 82 SRGVYAIFGFYDKKSVNTITSFCGTLHVSFI--------TPSF-----PTDGTHPFVIQM 128
++G+ A+ S N + S +H+ + +P P+ + +
Sbjct: 84 TQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLAS 143
Query: 129 RPD--LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVG-NINN 185
RP L +L L+ +W KF YDS+ + LQ+ LD A+ V+ V NI++
Sbjct: 144 RPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISH 203
Query: 186 DKKDEMYRSLFQDLELKKE-------RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIA 238
++ SLF ++ ++ RR IL + +++ + K H++
Sbjct: 204 -----VFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFV 258
Query: 239 NLGFTDGDLLKIQFG--GANVSGFQIVDY--DDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
N +D ++L + G QI D+ ++ R S+L G + ++
Sbjct: 259 NEEISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHRISSLLCDPQEG-YLQMLQ 317
Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
++ YD+V ++ AF + R S +C+ PW G + +K+ +
Sbjct: 318 ISNLYLYDSVLMLANAFHRKLEDRKWHSMASL--NCIRKSTKPWNGGRSMLDTIKKGHIT 375
Query: 355 GLSGNIKFDQNGKRINYTINIM-----ELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTS 409
GL+G ++F ++ I+ E RK+ W + +L E P G+
Sbjct: 376 GLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPMGSRLQ 435
Query: 410 GLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDG 469
GL T+ V T+LE P+VM+ +N +L +RY+G+ +D+ +AK GFKY++ DG
Sbjct: 436 GL---TLKVVTVLEEPFVMVAEN--ILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDG 490
Query: 470 KYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 529
+YG + +T WNGM+GEL+ +AD+AI+ +TIT RE V+DFSK +M + I+IKKP+
Sbjct: 491 RYGHQLHNTS-WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKPE 549
Query: 530 KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSEST 589
+ K +FS P + +W CI A V V++F+++R + + + S S
Sbjct: 550 E-KISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVR-----AQSAAQPRPSASA 603
Query: 590 NEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVER 649
+ +++W GAF++QG + S S++ RIV G WW FTLI+ SSYTANLAAFLTV R
Sbjct: 604 T---LHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSR 660
Query: 650 MVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRR------SKIAVFDKMW-TYMRSAEPSV 702
M +PI + +DLSKQ E++YGT+ + E+FR + + F ++W T ++
Sbjct: 661 MDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADN 720
Query: 703 FVRTTAEGVARVRKSKGKYAYLLESTMNEYIE-QRKPCDTMKVGGNLDSKGYGIATPKGS 761
V + +EG+ + + KG YA+L + + EY C +G ++ SKGYGIA GS
Sbjct: 721 CVSSPSEGIRKAK--KGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGS 778
Query: 762 SLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG-SGGGDSKEKTSALSLSNVAGVFYIL 820
R+ + +L+L + G LD LK KWW G C + ++ +L L + AGVF IL
Sbjct: 779 PYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCIL 838
Query: 821 VGGLGLAMLVALIEFCYKS 839
GL LA LVA +E + S
Sbjct: 839 AIGLLLACLVAALELWWNS 857
>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
Length = 1007
Score = 348 bits (893), Expect = 1e-95
Identities = 242/863 (28%), Positives = 420/863 (48%), Gaps = 80/863 (9%)
Query: 27 IQIGGLFPRGADQEYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAFCSQF 81
I IG +F A ++ FR + + +E ++T + ++ N F C
Sbjct: 27 IHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELM 86
Query: 82 SRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGT-------------HPFVIQM 128
++G+ A+ S ++ S +H+ + T GT + + +
Sbjct: 87 NQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSV 146
Query: 129 RPD--LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINND 186
RP L +L ++ Y W KF YDS+ + +Q LD +++ V V N N
Sbjct: 147 RPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNIN- 205
Query: 187 KKDEMYRSLFQDLELKKE-------RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIAN 239
+M +LF + +++ RR IL + +V+ H+II N
Sbjct: 206 ---KMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIIN 262
Query: 240 LGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERW--------STLEEKEYPGAHTT 291
D D+ ++ ++ I+ + +R STL + + P A
Sbjct: 263 EEINDVDVQELV--RRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNM 320
Query: 292 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 351
I ++ YD V ++ AF + R S + C+ + PW G + +K+
Sbjct: 321 EI--SNLYIYDTVLLLANAFHKKLEDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKG 376
Query: 352 QVEGLSGNIKFDQNGKRINYTINIM-----ELKTNGPRKIGYWSEVDKMVVTLTELPSGN 406
V GL+G ++F +NG N I+ E G RK+G W+ V + +LT+ N
Sbjct: 377 GVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLEN 436
Query: 407 DTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIV 466
+ G+ + V T+LE P+VM+ +N +L ++Y+G+ +D+ ++ + GF Y++ +
Sbjct: 437 NMRGV---VLRVVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVA 491
Query: 467 GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 526
D KYG+ D WNG+VGELV+ +ADI I+ LTIT RE V+DF+ +M + ++++
Sbjct: 492 PDHKYGSPQEDGT-WNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLR 550
Query: 527 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSS 586
+ +K+ +F+ L P +W CI + V ++++L++ +P + G T ++
Sbjct: 551 RAEKTVD-MFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNP-----PRLQMGSMTSTT 604
Query: 587 ESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 646
++NS+WF G+F++QG ++ +L+ R++ G WW F LI+ISSYTANLAAFLT
Sbjct: 605 -------LYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLT 657
Query: 647 VERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKI------AVFDKMWTYMRSAEP 700
+ R+ S I+S +DLSKQTEI YGT+ + E R + +++ +MW + +
Sbjct: 658 ITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMINRSNG 717
Query: 701 SVFVRTTAEGVARVRKSK-GKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATP 758
S E A ++K K G YA++ ++ + EY+ P C +G + +GYGIA
Sbjct: 718 S--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYGIALQ 775
Query: 759 KGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG-SGGGDSKEKTSALSLSNVAGVF 817
GS R+ + +L+L + G +D LK+KWW G+C D+K+K AL + + AGVF
Sbjct: 776 HGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSFAGVF 835
Query: 818 YILVGGLGLAMLVALIEFCYKSR 840
IL G+ L+ +A++E + R
Sbjct: 836 CILAAGIVLSCFIAMLETWWNKR 858
>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
Length = 885
Score = 236 bits (602), Expect = 7e-62
Identities = 184/616 (29%), Positives = 307/616 (49%), Gaps = 87/616 (14%)
Query: 294 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 352
K SA DAV V+ +A L K+ I RG C+ N + W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 353 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 403
+G++G ++F+++G R +IM L+ ++G ++ D+ ++ TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 404 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 438
G S + + TI + P+V +K ++ G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445
Query: 439 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 488
+ R+ G+C+DL ++A+ F Y++ +V DGK+G ++ ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505
Query: 489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 548
+ G+AD+ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564
Query: 549 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 606
+ + V+V+L+L+ RFSP+ GR +SE E + +++WFS G +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615
Query: 607 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 662
G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D +
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675
Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
+ Y T+ S +FRR M+ +M + AE + VR +K +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728
Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDK 782
++ +S + E+ E + CD + G G+GI K S + V+L++LK +E G ++
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787
Query: 783 LKNKWWYDKGECGSGGGDSKEKTSA-LSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRA 841
L +K W EC DS+ A L+ N+AGVF ++ GG+ + + IE YK
Sbjct: 788 L-DKTWVRYQEC-----DSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK 841
Query: 842 EAKR--MKVAKNAQNI 855
+A+R M++A A N+
Sbjct: 842 DARRKQMQLAFAAVNV 857
>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
Length = 938
Score = 236 bits (602), Expect = 7e-62
Identities = 184/616 (29%), Positives = 307/616 (49%), Gaps = 87/616 (14%)
Query: 294 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 352
K SA DAV V+ +A L K+ I RG C+ N + W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 353 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 403
+G++G ++F+++G R +IM L+ ++G ++ D+ ++ TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 404 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 438
G S + + TI + P+V +K ++ G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445
Query: 439 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 488
+ R+ G+C+DL ++A+ F Y++ +V DGK+G ++ ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505
Query: 489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 548
+ G+AD+ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564
Query: 549 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 606
+ + V+V+L+L+ RFSP+ GR +SE E + +++WFS G +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615
Query: 607 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 662
G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D +
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675
Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
+ Y T+ S +FRR M+ +M + AE + VR +K +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728
Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDK 782
++ +S + E+ E + CD + G G+GI K S + V+L++LK +E G ++
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787
Query: 783 LKNKWWYDKGECGSGGGDSKEKTSA-LSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRA 841
L +K W EC DS+ A L+ N+AGVF ++ GG+ + + IE YK
Sbjct: 788 L-DKTWVRYQEC-----DSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK 841
Query: 842 EAKR--MKVAKNAQNI 855
+A+R M++A A N+
Sbjct: 842 DARRKQMQLAFAAVNV 857
>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
Length = 901
Score = 236 bits (602), Expect = 7e-62
Identities = 184/616 (29%), Positives = 307/616 (49%), Gaps = 87/616 (14%)
Query: 294 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 352
K SA DAV V+ +A L K+ I RG C+ N + W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 353 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 403
+G++G ++F+++G R +IM L+ ++G ++ D+ ++ TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 404 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 438
G S + + TI + P+V +K ++ G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445
Query: 439 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 488
+ R+ G+C+DL ++A+ F Y++ +V DGK+G ++ ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505
Query: 489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 548
+ G+AD+ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564
Query: 549 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 606
+ + V+V+L+L+ RFSP+ GR +SE E + +++WFS G +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615
Query: 607 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 662
G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D +
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675
Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
+ Y T+ S +FRR M+ +M + AE + VR +K +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728
Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDK 782
++ +S + E+ E + CD + G G+GI K S + V+L++LK +E G ++
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787
Query: 783 LKNKWWYDKGECGSGGGDSKEKTSA-LSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRA 841
L +K W EC DS+ A L+ N+AGVF ++ GG+ + + IE YK
Sbjct: 788 L-DKTWVRYQEC-----DSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK 841
Query: 842 EAKR--MKVAKNAQNI 855
+A+R M++A A N+
Sbjct: 842 DARRKQMQLAFAAVNV 857
>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
[Homo sapiens]
Length = 1484
Score = 186 bits (472), Expect = 8e-47
Identities = 183/740 (24%), Positives = 329/740 (44%), Gaps = 100/740 (13%)
Query: 136 LLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKK---WQVTAINVGNINNDKKDEMY 192
+L+++E Y W F+ + G + S E W++ + + +++ D D
Sbjct: 157 MLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKI 216
Query: 193 RSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQF 252
++ + L+ ++L C +++ I + ++G GY +I+ +L D D + +F
Sbjct: 217 QNQLKKLQ---SPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPAEF 273
Query: 253 GGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFR 312
+S V YD+ W +Y A D + ++T A
Sbjct: 274 PTGLIS----VSYDE---------W------DYG---------LPARVRDGIAIITTAAS 305
Query: 313 NLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYT 372
++ + I ++ C Q + R L V EG N+ F ++G +++
Sbjct: 306 DMLSEHSFIPEPKSS--CYNTHEKRIYQSNMLNRYLINVTFEGR--NLSFSEDGYQMHPK 361
Query: 373 INIMEL-KTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKK 431
+ I+ L K ++G W + + +T E+ + + T+ E+P+V+++
Sbjct: 362 LVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVES 421
Query: 432 ---------------NHEMLEGNERYE----------GYCVDLAAEIAKHCGFKYKLTIV 466
++ N+ E G+C+D+ +I+K F Y L +V
Sbjct: 422 VDPLSGTCMRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLV 481
Query: 467 GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 526
+GK+G + T WNGM+GE+V +A +A+ LTI R EV+DFS PF+ GIS+M+
Sbjct: 482 TNGKHGKKINGT--WNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVS 539
Query: 527 KPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQS 585
+ +FL+P + ++W M V I +V +F+ FSP ++ DGRE
Sbjct: 540 R-SNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYN-RCLADGREPGG 597
Query: 586 SESTNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 644
F I ++W G + +P+ + +I+ VW FF +I ++SYTANLAAF
Sbjct: 598 P----SFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAF 653
Query: 645 LTVERMVSPIESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSA 698
+ E V + D Q +GT+ +GST+ R + + +M YM
Sbjct: 654 MIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN----YAEMHAYM--- 706
Query: 699 EPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGI 755
F + + K+ A++ ++ + Y+ R + C + +G S GYGI
Sbjct: 707 --GKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGI 764
Query: 756 ATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAG 815
A K S + V+LA+L+L G +++L+ W G C + ++ +S L + N+AG
Sbjct: 765 AIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGICHN--EKNEVMSSQLDIDNMAG 820
Query: 816 VFYILVGGLGLAMLVALIEF 835
VFY+ LG AM ++LI F
Sbjct: 821 VFYM----LGAAMALSLITF 836
>gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor
[Homo sapiens]
Length = 1233
Score = 182 bits (462), Expect = 1e-45
Identities = 192/792 (24%), Positives = 335/792 (42%), Gaps = 103/792 (13%)
Query: 82 SRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIE 141
+ V I F ++ I S G V +TP P + + L+ L ++E
Sbjct: 101 TEAVAQILDFISSQTHVPILSISGGSAV-VLTPKEPGSAFLQLGVSLEQQLQ-VLFKVLE 158
Query: 142 YYQWDKFAYLYDSDRG----LSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 197
Y W FA + G L ++AV D A+ W++ + + + L +
Sbjct: 159 EYDWSAFAVITSLHPGHALFLEGVRAVAD-ASHVSWRLLDVVTLELGPGGPRARTQRLLR 217
Query: 198 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 257
L+ + C R++ + + G G+ +++ NL D A
Sbjct: 218 QLDAPV---FVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTD--------APP 266
Query: 258 SGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRK 316
+ F + L+S E W +L +K D V ++ + +
Sbjct: 267 ATFPV-----GLISVVTESWRLSLRQK----------------VRDGVAILALGAHSYWR 305
Query: 317 QRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIM 376
Q + AGDC +P R L V EG + F G + T+ ++
Sbjct: 306 QHGTLP--APAGDCRVHPGPVSPAREAFYRHLLNVTWEGR--DFSFSPGGYLVQPTMVVI 361
Query: 377 ELKTNGP-RKIGYWSE-VDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKK--- 431
L + +G W V M + S + ++++ + V T+ E P+V+++
Sbjct: 362 ALNRHRLWEMVGRWEHGVLYMKYPVWPRYSASLQPVVDSRHLTVATLEERPFVIVESPDP 421
Query: 432 ----------------NHEMLEGNER------YEGYCVDLAAEIAKHCGFKYKLTIVGDG 469
NH G+ +G+C+D+ ++A+ F Y L +V +G
Sbjct: 422 GTGGCVPNTVPCRRQSNHTFSSGDVAPYTKLCCKGFCIDILKKLARVVKFSYDLYLVTNG 481
Query: 470 KYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 529
K+G R +WNGM+GE+ Y +AD+AI LTI R E++DFS PF+ GIS+M+ +
Sbjct: 482 KHGKRVRG--VWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVAR-S 538
Query: 530 KSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSES 588
+FL+P + +W M V V++ +F+ FSP ++ + G+++
Sbjct: 539 NGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYN-QNLTRGKKSGGP-- 595
Query: 589 TNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 647
F I S+W I +PR + +I+ VW FF +I ++SYTANLAAF+
Sbjct: 596 --AFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQ 653
Query: 648 ERMVSPIESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPS 701
E+ + + D Q +GT+ +GST+ R + + M T+M
Sbjct: 654 EQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSN----YRDMHTHMVK---- 705
Query: 702 VFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATP 758
F + + E K A++ ++ + Y+ + + C + +G + GYGIA
Sbjct: 706 -FNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQ 764
Query: 759 KGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFY 818
K S + A++LA+L+ G KL+ W G C + ++ +S L + N+AGVFY
Sbjct: 765 KDSHWKRAIDLALLQFLGDGETQKLETVWL--SGICQN--EKNEVMSSKLDIDNMAGVFY 820
Query: 819 ILVGGLGLAMLV 830
+L+ +GLA+LV
Sbjct: 821 MLLVAMGLALLV 832
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
[Homo sapiens]
Length = 1336
Score = 171 bits (434), Expect = 2e-42
Identities = 120/400 (30%), Positives = 205/400 (51%), Gaps = 34/400 (8%)
Query: 443 EGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTI 502
+G+C+D+ +A GF Y L +V +GK+G + +WNGM+GE+ Y +AD+AI LTI
Sbjct: 485 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDG--VWNGMIGEVFYQRADMAIGSLTI 542
Query: 503 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 561
R E++DFS PF+ GIS+M+ + +FL+P + +W M V V+V +
Sbjct: 543 NEERSEIVDFSVPFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTV 601
Query: 562 FLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGR 620
F+ SP ++ T + F I S+W + +PR + +
Sbjct: 602 FIFEYLSPVGYNR-----SLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSK 656
Query: 621 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQ------TEIAYGTLDSG 674
I+ VW FF +I ++SYTANLAAF+ E V + D Q + +GT+ +G
Sbjct: 657 IMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNG 716
Query: 675 STKEFFRRSKIAVFDKMWTYM-RSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYI 733
ST++ R + + M +YM R +P V E + +++ K A++ ++ + Y+
Sbjct: 717 STEKNIRSN----YPDMHSYMVRYNQPRV-----EEALTQLKAGK-LDAFIYDAAVLNYM 766
Query: 734 EQR-KPCDTMKVGGN--LDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYD 790
++ + C + +G + GYGIA KGS + ++LA+L+ ++ L+ W
Sbjct: 767 ARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWL-- 824
Query: 791 KGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLV 830
G C + + +S L + N+AGVFY+L+ +GL++LV
Sbjct: 825 SGICHN--DKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLV 862
>gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2
precursor [Homo sapiens]
Length = 1281
Score = 171 bits (432), Expect = 4e-42
Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)
Query: 189 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 246
D + ++LKK ++L C +D+ I+ + ++G + +I+ +L + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266
Query: 247 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 305
L+ +F SG V YDD W +LE + G T +S L +
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313
Query: 306 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 360
+A + +R E+ + N V W G+ + QV V L+ +
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370
Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 416
++++ GK N+T+++ + D +VTL E P D L +T
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429
Query: 417 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
V T+ +V + + +E + + +G+C+D+ ++++ F Y L +V +GK+G +
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489
Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
+WNGM+GE+VY +A +A+ LTI R EV+DFS PF+ GIS+M+ +
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546
Query: 536 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
+FL+P + +W M V I ++ +F+ FSP ++ G+ F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601
Query: 595 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
++W G + +P+ + +I+ VW FF +I ++SYTANLAAF+ E V
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661
Query: 654 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
+ D Q +GT+ +GST+ R + + M YM +
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709
Query: 708 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 761
+GV A V GK A++ ++ + Y R + C + +G + GYGIA KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769
Query: 762 SLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILV 821
+ ++LA+L+ G +++L+ W G C + ++ +S L + N+AGVFY+L
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGICHN--EKNEVMSSQLDIDNMAGVFYMLA 825
Query: 822 GGLGLAMLVALIEFCY 837
+ L+++ + E +
Sbjct: 826 AAMALSLITFIWEHLF 841
>gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 171 bits (432), Expect = 4e-42
Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)
Query: 189 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 246
D + ++LKK ++L C +D+ I+ + ++G + +I+ +L + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266
Query: 247 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 305
L+ +F SG V YDD W +LE + G T +S L +
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313
Query: 306 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 360
+A + +R E+ + N V W G+ + QV V L+ +
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370
Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 416
++++ GK N+T+++ + D +VTL E P D L +T
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429
Query: 417 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
V T+ +V + + +E + + +G+C+D+ ++++ F Y L +V +GK+G +
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489
Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
+WNGM+GE+VY +A +A+ LTI R EV+DFS PF+ GIS+M+ +
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546
Query: 536 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
+FL+P + +W M V I ++ +F+ FSP ++ G+ F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601
Query: 595 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
++W G + +P+ + +I+ VW FF +I ++SYTANLAAF+ E V
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661
Query: 654 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
+ D Q +GT+ +GST+ R + + M YM +
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709
Query: 708 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 761
+GV A V GK A++ ++ + Y R + C + +G + GYGIA KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769
Query: 762 SLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILV 821
+ ++LA+L+ G +++L+ W G C + ++ +S L + N+AGVFY+L
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGICHN--EKNEVMSSQLDIDNMAGVFYMLA 825
Query: 822 GGLGLAMLVALIEFCY 837
+ L+++ + E +
Sbjct: 826 AAMALSLITFIWEHLF 841
>gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 171 bits (432), Expect = 4e-42
Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)
Query: 189 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 246
D + ++LKK ++L C +D+ I+ + ++G + +I+ +L + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266
Query: 247 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 305
L+ +F SG V YDD W +LE + G T +S L +
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313
Query: 306 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 360
+A + +R E+ + N V W G+ + QV V L+ +
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370
Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 416
++++ GK N+T+++ + D +VTL E P D L +T
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429
Query: 417 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
V T+ +V + + +E + + +G+C+D+ ++++ F Y L +V +GK+G +
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489
Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
+WNGM+GE+VY +A +A+ LTI R EV+DFS PF+ GIS+M+ +
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546
Query: 536 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
+FL+P + +W M V I ++ +F+ FSP ++ G+ F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601
Query: 595 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
++W G + +P+ + +I+ VW FF +I ++SYTANLAAF+ E V
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661
Query: 654 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
+ D Q +GT+ +GST+ R + + M YM +
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709
Query: 708 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 761
+GV A V GK A++ ++ + Y R + C + +G + GYGIA KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769
Query: 762 SLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILV 821
+ ++LA+L+ G +++L+ W G C + ++ +S L + N+AGVFY+L
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGICHN--EKNEVMSSQLDIDNMAGVFYMLA 825
Query: 822 GGLGLAMLVALIEFCY 837
+ L+++ + E +
Sbjct: 826 AAMALSLITFIWEHLF 841
>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
[Homo sapiens]
Length = 1043
Score = 163 bits (412), Expect = 7e-40
Identities = 119/401 (29%), Positives = 196/401 (48%), Gaps = 30/401 (7%)
Query: 444 GYCVDLAAEIAKHCGFKYKLTIVGDGKYGA-RDADTKIWNGMVGELVYGKADIAIAPLTI 502
GYC+DL +A+ F ++L +VGDGKYGA RD W G+VG+L+ G+A +A+ +I
Sbjct: 478 GYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGR---WTGLVGDLLAGRAHMAVTSFSI 534
Query: 503 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 562
R +V+DF+ PF S + IM++ + P + +F+ PL + W +GV L
Sbjct: 535 NSARSQVVDFTSPFFSTSLGIMVRARDTASP-IGAFMWPLHWSTW-------LGVFAALH 586
Query: 563 LVSRF-SPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRI 621
L + F + YEW + R S + N + L F R +P+ +GR+
Sbjct: 587 LTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAIL--FRRTVSSKTPKCPTGRL 644
Query: 622 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS---KQTEIAYGTLDSGSTKE 678
+ +W F L+++SSYTANLAA + ++ + D +GT+ S +
Sbjct: 645 LMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEA 704
Query: 679 FFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKY-AYLLESTMNEY-IEQR 736
+ ++S F M +MR TT GVA + K A++++ ++ +Y +
Sbjct: 705 YIKKS----FPDMHAHMRRHS----APTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSID 756
Query: 737 KPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 796
C + VG +GYGI P+ S L + ++ + + G +D L +K WY CG
Sbjct: 757 ADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK-WYKMVPCGK 815
Query: 797 GGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 837
E T +S+ + AG+F +L GLG A+L +L E +
Sbjct: 816 RVFAVTE-TLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAF 855
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,955,386
Number of Sequences: 37866
Number of extensions: 1235015
Number of successful extensions: 3007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2811
Number of HSP's gapped (non-prelim): 47
length of query: 883
length of database: 18,247,518
effective HSP length: 111
effective length of query: 772
effective length of database: 14,044,392
effective search space: 10842270624
effective search space used: 10842270624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.