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Search of human proteins with 134152686
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134152686 receptor tyrosine kinase-like orphan receptor 1
isoform 2 [Homo sapiens]
(393 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134152686 receptor tyrosine kinase-like orphan receptor 1 iso... 825 0.0
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso... 821 0.0
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec... 520 e-147
gi|4505881 plasminogen [Homo sapiens] 88 2e-17
gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo s... 88 2e-17
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s... 88 2e-17
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho... 88 2e-17
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s... 85 1e-16
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s... 85 1e-16
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 84 3e-16
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 81 1e-15
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 80 3e-15
gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 78 2e-14
gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 78 2e-14
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens] 73 5e-13
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 65 8e-11
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 65 8e-11
gi|145275213 coagulation factor XII precursor [Homo sapiens] 65 1e-10
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 62 7e-10
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 62 7e-10
gi|24041012 kringle-containing transmembrane protein 1 isoform 2... 62 9e-10
gi|227116325 kringle-containing transmembrane protein 1 isoform ... 62 9e-10
gi|222352127 sidekick 2 [Homo sapiens] 60 3e-09
gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken) ... 60 3e-09
gi|110349719 titin isoform N2-A [Homo sapiens] 60 4e-09
gi|4504383 HGF activator preproprotein [Homo sapiens] 60 4e-09
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 59 1e-08
gi|15147240 brother of CDO [Homo sapiens] 58 2e-08
gi|110349717 titin isoform novex-2 [Homo sapiens] 57 4e-08
gi|110349713 titin isoform novex-1 [Homo sapiens] 57 4e-08
>gi|134152686 receptor tyrosine kinase-like orphan receptor 1
isoform 2 [Homo sapiens]
Length = 393
Score = 825 bits (2132), Expect = 0.0
Identities = 393/393 (100%), Positives = 393/393 (100%)
Query: 1 MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL 60
MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL
Sbjct: 1 MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL 60
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN
Sbjct: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR 180
LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR
Sbjct: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR 180
Query: 181 FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS 240
FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS
Sbjct: 181 FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS 240
Query: 241 VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG 300
VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG
Sbjct: 241 VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG 300
Query: 301 IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS 360
IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS
Sbjct: 301 IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS 360
Query: 361 YCRNPGNQKEAPWCFTLDENFKSDLCDIPACGK 393
YCRNPGNQKEAPWCFTLDENFKSDLCDIPACGK
Sbjct: 361 YCRNPGNQKEAPWCFTLDENFKSDLCDIPACGK 393
>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
isoform 1 [Homo sapiens]
Length = 937
Score = 821 bits (2121), Expect = 0.0
Identities = 391/391 (100%), Positives = 391/391 (100%)
Query: 1 MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL 60
MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL
Sbjct: 1 MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL 60
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN
Sbjct: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR 180
LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR
Sbjct: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR 180
Query: 181 FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS 240
FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS
Sbjct: 181 FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS 240
Query: 241 VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG 300
VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG
Sbjct: 241 VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG 300
Query: 301 IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS 360
IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS
Sbjct: 301 IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS 360
Query: 361 YCRNPGNQKEAPWCFTLDENFKSDLCDIPAC 391
YCRNPGNQKEAPWCFTLDENFKSDLCDIPAC
Sbjct: 361 YCRNPGNQKEAPWCFTLDENFKSDLCDIPAC 391
>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
Length = 943
Score = 520 bits (1338), Expect = e-147
Identities = 240/388 (61%), Positives = 295/388 (76%), Gaps = 1/388 (0%)
Query: 4 PRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEP 63
PRR P + AALLL+ + + L + L P + K +L EP
Sbjct: 8 PRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEP 67
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+NNIT GQTA LHCKV+GNPPP +RW KNDAPVVQEPRR+ R T YGSRLRI++LDT
Sbjct: 68 VNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDT 127
Query: 124 TDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIG 183
TDTGY+QCVATNG + +++TGVLFV+ GP + + + D+Y EDGFCQPYRGIACARFIG
Sbjct: 128 TDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGIACARFIG 187
Query: 184 NRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPK 243
NRT+Y++SL MQGEIEN+ITAAFTMIGTS+HLSD+CSQFAIPS CH+ FP CD S PK
Sbjct: 188 NRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRTPK 247
Query: 244 PRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPM 303
PR+LCRDECE+LE+ LC+ EY ARSNP+ILMRL+LP CE LP PESP+AANC+RIGIP
Sbjct: 248 PRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIP- 306
Query: 304 ADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCR 363
A+ + + H+CYN +G+DYRGT S TKSG QCQPW Q+PH+H ++ FPEL GGH+YCR
Sbjct: 307 AERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCR 366
Query: 364 NPGNQKEAPWCFTLDENFKSDLCDIPAC 391
NPG Q E PWCFT ++N + +LCD+P+C
Sbjct: 367 NPGGQMEGPWCFTQNKNVRMELCDVPSC 394
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 87.8 bits (216), Expect = 2e-17
Identities = 38/87 (43%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 305 DPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRN 364
D + +C + +G +Y G +S T SG +CQ W+SQ PH H + +FP N +YCRN
Sbjct: 177 DILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRN 236
Query: 365 PGNQKEAPWCFTLDENFKSDLCDIPAC 391
P +++ PWCFT D N + +LCDIP C
Sbjct: 237 P-DRELRPWCFTTDPNKRWELCDIPRC 262
Score = 86.3 bits (212), Expect = 4e-17
Identities = 38/81 (46%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 311 HKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKE 370
++C TG +YRG V+VT SG CQ W++Q PHTH T FP N +YCRNP + K
Sbjct: 273 YQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNP-DGKR 331
Query: 371 APWCFTLDENFKSDLCDIPAC 391
APWC T + + + C IP+C
Sbjct: 332 APWCHTTNSQVRWEYCKIPSC 352
Score = 81.3 bits (199), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
Query: 278 KLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPW 337
K+P+C+ P A P P+ ++ CY+ G YRGT S T +G++CQ W
Sbjct: 348 KIPSCDSSPVSTEQLAPTAP----PELTPVVQD--CYHGDGQSYRGTSSTTTTGKKCQSW 401
Query: 338 NSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPAC 391
+S PH H T +P +YCRNP K PWCFT D + + + C++ C
Sbjct: 402 SSMTPHRHQKTPENYPNAGLTMNYCRNPDADK-GPWCFTTDPSVRWEYCNLKKC 454
Score = 80.1 bits (196), Expect = 3e-15
Identities = 34/80 (42%), Positives = 44/80 (55%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+C G +YRGT+S TK+G CQ W+S PH F+ P +YCRNP N +
Sbjct: 102 ECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQG 161
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+T D + D CDI C
Sbjct: 162 PWCYTTDPEKRYDYCDILEC 181
Score = 70.1 bits (170), Expect = 3e-12
Identities = 64/243 (26%), Positives = 86/243 (35%), Gaps = 53/243 (21%)
Query: 153 PPTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESL---HMQGEIENQITAAFTMI 209
PP +P D Y DG Q YRG + G + S+ Q EN A TM
Sbjct: 367 PPELTPVVQDCYHGDG--QSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMN 424
Query: 210 GTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARS 269
+ +DK P+C T + +C TE
Sbjct: 425 YCRNPDADKG-------------PWCFTTDPSVRWEYCNLKKCS-------GTEASVVAP 464
Query: 270 NPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTK 329
P++L LP E+P +C+ G YRG + T
Sbjct: 465 PPVVL----------LPDVETPSEEDCMF-----------------GNGKGYRGKRATTV 497
Query: 330 SGRQCQPWNSQYPHTHT-FTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDI 388
+G CQ W +Q PH H+ FT P +YCRNP PWC+T + D CD+
Sbjct: 498 TGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDV 557
Query: 389 PAC 391
P C
Sbjct: 558 PQC 560
>gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo
sapiens]
Length = 210
Score = 87.8 bits (216), Expect = 2e-17
Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Query: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
NK++ C G Y+GTVS+TKSG +CQPW+S PH H+F + + +YCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393
++ PWCFT + + ++CDIP C +
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
sapiens]
Length = 290
Score = 87.8 bits (216), Expect = 2e-17
Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Query: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
NK++ C G Y+GTVS+TKSG +CQPW+S PH H+F + + +YCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393
++ PWCFT + + ++CDIP C +
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
Score = 77.0 bits (188), Expect = 3e-14
Identities = 33/80 (41%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 268
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+TLD + + + C I C
Sbjct: 269 PWCYTLDPHTRWEYCAIKTC 288
>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
sapiens]
Length = 728
Score = 87.8 bits (216), Expect = 2e-17
Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Query: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
NK++ C G Y+GTVS+TKSG +CQPW+S PH H+F + + +YCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393
++ PWCFT + + ++CDIP C +
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
Score = 77.0 bits (188), Expect = 3e-14
Identities = 33/80 (41%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 268
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+TLD + + + C I C
Sbjct: 269 PWCYTLDPHTRWEYCAIKTC 288
Score = 75.1 bits (183), Expect = 1e-13
Identities = 36/81 (44%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+C G YRGTV+ +G CQ W+SQYPH H T F + +YCRNP + E+
Sbjct: 304 ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNP-DGSES 362
Query: 372 PWCFTLDENFKSDLC-DIPAC 391
PWCFT D N + C IP C
Sbjct: 363 PWCFTTDPNIRVGYCSQIPNC 383
Score = 64.7 bits (156), Expect = 1e-10
Identities = 42/127 (33%), Positives = 58/127 (45%), Gaps = 20/127 (15%)
Query: 282 CEDLPQ-----PESPEAANC------IRIG----IPMADPINKNHKCYNSTGVDYRGTVS 326
C+DL + P+ E+ C IR+G IP D ++ CY G +Y G +S
Sbjct: 346 CKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD-MSHGQDCYRGNGKNYMGNLS 404
Query: 327 VTKSGRQCQPW--NSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSD 384
T+SG C W N + H H F +LN +YCRNP + PWC+T + D
Sbjct: 405 QTRSGLTCSMWDKNMEDLHRHIFWEPDASKLN--ENYCRNPDDDAHGPWCYTGNPLIPWD 462
Query: 385 LCDIPAC 391
C I C
Sbjct: 463 YCPISRC 469
>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
sapiens]
Length = 285
Score = 85.1 bits (209), Expect = 1e-16
Identities = 37/88 (42%), Positives = 53/88 (60%), Gaps = 7/88 (7%)
Query: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
NK++ C G Y+GTVS+TKSG +CQPW+S PH H++ E +YCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQE-----NYCRNP 175
Query: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393
++ PWCFT + + ++CDIP C +
Sbjct: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 203
Score = 77.0 bits (188), Expect = 3e-14
Identities = 33/80 (41%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+TLD + + + C I C
Sbjct: 264 PWCYTLDPHTRWEYCAIKTC 283
>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
Length = 723
Score = 85.1 bits (209), Expect = 1e-16
Identities = 37/88 (42%), Positives = 53/88 (60%), Gaps = 7/88 (7%)
Query: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
NK++ C G Y+GTVS+TKSG +CQPW+S PH H++ E +YCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQE-----NYCRNP 175
Query: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393
++ PWCFT + + ++CDIP C +
Sbjct: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 203
Score = 77.0 bits (188), Expect = 3e-14
Identities = 33/80 (41%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+TLD + + + C I C
Sbjct: 264 PWCYTLDPHTRWEYCAIKTC 283
Score = 75.1 bits (183), Expect = 1e-13
Identities = 36/81 (44%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+C G YRGTV+ +G CQ W+SQYPH H T F + +YCRNP + E+
Sbjct: 299 ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNP-DGSES 357
Query: 372 PWCFTLDENFKSDLC-DIPAC 391
PWCFT D N + C IP C
Sbjct: 358 PWCFTTDPNIRVGYCSQIPNC 378
Score = 64.7 bits (156), Expect = 1e-10
Identities = 42/127 (33%), Positives = 58/127 (45%), Gaps = 20/127 (15%)
Query: 282 CEDLPQ-----PESPEAANC------IRIG----IPMADPINKNHKCYNSTGVDYRGTVS 326
C+DL + P+ E+ C IR+G IP D ++ CY G +Y G +S
Sbjct: 341 CKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD-MSHGQDCYRGNGKNYMGNLS 399
Query: 327 VTKSGRQCQPW--NSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSD 384
T+SG C W N + H H F +LN +YCRNP + PWC+T + D
Sbjct: 400 QTRSGLTCSMWDKNMEDLHRHIFWEPDASKLN--ENYCRNPDDDAHGPWCYTGNPLIPWD 457
Query: 385 LCDIPAC 391
C I C
Sbjct: 458 YCPISRC 464
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 83.6 bits (205), Expect = 3e-16
Identities = 35/80 (43%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAP 372
C G +YRG V T+SGR+CQ W+ Q+PH H F +F + +YCRNP + E P
Sbjct: 205 CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNP-DGSERP 263
Query: 373 WCFTLDENFKSDLCDIPACG 392
WC+T D + + CD+P CG
Sbjct: 264 WCYTTDPQIEREFCDLPRCG 283
Score = 78.6 bits (192), Expect = 9e-15
Identities = 32/79 (40%), Positives = 42/79 (53%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAP 372
CY+ G YRGTVS T+ G QCQ W+++ PH FT P ++CRNP P
Sbjct: 384 CYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGP 443
Query: 373 WCFTLDENFKSDLCDIPAC 391
WC+T+D D C + C
Sbjct: 444 WCYTMDPRTPFDYCALRRC 462
Score = 70.5 bits (171), Expect = 3e-12
Identities = 30/74 (40%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAP 372
C+ G YRGT + T +G CQ W++Q PH H FT ++ + ++CRNP + EAP
Sbjct: 297 CFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNP-DGSEAP 355
Query: 373 WCFTLDENFKSDLC 386
WCFTL ++ C
Sbjct: 356 WCFTLRPGMRAAFC 369
Score = 68.9 bits (167), Expect = 7e-12
Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 6/81 (7%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGG--HSYCRNPGNQKE 370
C + GV YRGT++ T G CQ W+ ++P+ H +T P L G ++CRNP
Sbjct: 124 CIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYT----PTLRNGLEENFCRNPDGDPG 179
Query: 371 APWCFTLDENFKSDLCDIPAC 391
PWC+T D + C I +C
Sbjct: 180 GPWCYTTDPAVRFQSCGIKSC 200
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 81.3 bits (199), Expect = 1e-15
Identities = 71/267 (26%), Positives = 105/267 (39%), Gaps = 50/267 (18%)
Query: 130 QCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYM 189
QC T + +ST V P SP D Y DG Q YRG G
Sbjct: 1244 QCPVTESSVLATSTAV---SEQAPTEQSPTVQDCYHGDG--QSYRGSFSTTVTGRTCQSW 1298
Query: 190 ESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFP-----YCDETSSVPKP 244
S+ +Q T + G + + I C+ P YC+ T
Sbjct: 1299 SSMTPHW---HQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLT------ 1349
Query: 245 RDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMA 304
+C ++E+ L T + + +P+ E LP E+P + G+
Sbjct: 1350 ------QCPVMESTLLTTPTV-----------VPVPSTE-LPSEEAPTENST---GV--- 1385
Query: 305 DPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRN 364
CY G YRGT+S T +GR CQ W+S PH H L +P +YCRN
Sbjct: 1386 ------QDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
Query: 365 PGNQKEAPWCFTLDENFKSDLCDIPAC 391
P + + PWC+T+D + + + C++ C
Sbjct: 1440 P-DAEIRPWCYTMDPSVRWEYCNLTRC 1465
Score = 78.6 bits (192), Expect = 9e-15
Identities = 33/80 (41%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH H T +P +YCRNP +
Sbjct: 1615 QCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNP-DADTG 1673
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWCFT+D + + + C++ C
Sbjct: 1674 PWCFTMDPSIRWEYCNLTRC 1693
Score = 77.8 bits (190), Expect = 2e-14
Identities = 35/81 (43%), Positives = 50/81 (61%), Gaps = 5/81 (6%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGG--HSYCRNPGNQKE 370
CY+ G YRG+ S T +GR CQ W+S PH H T +P NGG +YCRNP + +
Sbjct: 1168 CYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYP--NGGLTRNYCRNP-DAEI 1224
Query: 371 APWCFTLDENFKSDLCDIPAC 391
+PWC+T+D N + + C++ C
Sbjct: 1225 SPWCYTMDPNVRWEYCNLTQC 1245
Score = 77.4 bits (189), Expect = 2e-14
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 8/117 (6%)
Query: 277 LKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQP 336
L P +P E+P P P+ ++ CY+ G YRG S T +GR CQ
Sbjct: 1473 LTTPTVAPVPSTEAPSEQ-----APPEKSPVVQD--CYHGDGRSYRGISSTTVTGRTCQS 1525
Query: 337 WNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACGK 393
W+S PH H T +P +YCRNP + K+ PWC+T D + + C++ C +
Sbjct: 1526 WSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYTTDPCVRWEYCNLTQCSE 1581
Score = 76.6 bits (187), Expect = 4e-14
Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G Y+GT +T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 939 ECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNP-DPVAA 997
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+T D + + + C++ C
Sbjct: 998 PWCYTTDPSVRWEYCNLTRC 1017
Score = 76.6 bits (187), Expect = 4e-14
Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAP 372
CY G YRGT S T +GR CQ W+S PH H+ T +P +YCRNP + + P
Sbjct: 1054 CYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNP-DAEIRP 1112
Query: 373 WCFTLDENFKSDLCDIPAC 391
WC+T+D + + + C++ C
Sbjct: 1113 WCYTMDPSVRWEYCNLTQC 1131
Score = 74.3 bits (181), Expect = 2e-13
Identities = 32/80 (40%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 825 ECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNP-DPVAA 883
Query: 372 PWCFTLDENFKSDLCDIPAC 391
P+C+T D + + + C++ C
Sbjct: 884 PYCYTRDPSVRWEYCNLTQC 903
Score = 73.9 bits (180), Expect = 2e-13
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 141 ECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNP-DAVAA 199
Query: 372 PWCFTLDENFKSDLCDIPAC 391
P+C+T D + + C++ C
Sbjct: 200 PYCYTRDPGVRWEYCNLTQC 219
Score = 73.9 bits (180), Expect = 2e-13
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 255 ECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNP-DAVAA 313
Query: 372 PWCFTLDENFKSDLCDIPAC 391
P+C+T D + + C++ C
Sbjct: 314 PYCYTRDPGVRWEYCNLTQC 333
Score = 73.9 bits (180), Expect = 2e-13
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 369 ECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNP-DAVAA 427
Query: 372 PWCFTLDENFKSDLCDIPAC 391
P+C+T D + + C++ C
Sbjct: 428 PYCYTRDPGVRWEYCNLTQC 447
Score = 73.9 bits (180), Expect = 2e-13
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 483 ECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNP-DAVAA 541
Query: 372 PWCFTLDENFKSDLCDIPAC 391
P+C+T D + + C++ C
Sbjct: 542 PYCYTRDPGVRWEYCNLTQC 561
Score = 73.9 bits (180), Expect = 2e-13
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 597 ECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNP-DAVAA 655
Query: 372 PWCFTLDENFKSDLCDIPAC 391
P+C+T D + + C++ C
Sbjct: 656 PYCYTRDPGVRWEYCNLTQC 675
Score = 73.9 bits (180), Expect = 2e-13
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+ G YRGT S T +GR CQ W+S PH+H+ T +P +YCRNP + A
Sbjct: 711 ECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNP-DAVAA 769
Query: 372 PWCFTLDENFKSDLCDIPAC 391
P+C+T D + + C++ C
Sbjct: 770 PYCYTRDPGVRWEYCNLTQC 789
Score = 73.2 bits (178), Expect = 4e-13
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAP 372
CY+ G YRGT S T +GR CQ W+S PH H T +P +YCRNP + AP
Sbjct: 28 CYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRNP-DAVAAP 86
Query: 373 WCFTLDENFKSDLCDIPAC 391
+C+T D + + C++ C
Sbjct: 87 YCYTRDPGVRWEYCNLTQC 105
Score = 65.9 bits (159), Expect = 6e-11
Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 299 IGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTH-TFTALRFPELNG 357
I +P P ++ C G YRG + T +G CQ W +Q PH H TF
Sbjct: 1707 IQVPSLGPPSEQD-CMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGL 1765
Query: 358 GHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPAC 391
+YCRNP PWC+T++ D CDIP C
Sbjct: 1766 EKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLC 1799
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 80.1 bits (196), Expect = 3e-15
Identities = 31/81 (38%), Positives = 45/81 (55%)
Query: 313 CYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAP 372
C G +YRG V++T+SG +CQ W S+YPH + P + ++CRNP + P
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
Query: 373 WCFTLDENFKSDLCDIPACGK 393
WC+T D + C IP CG+
Sbjct: 168 WCYTTDPTVRRQECSIPVCGQ 188
Score = 42.4 bits (98), Expect = 7e-04
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 10/85 (11%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYP-----HTHTFTALRFPELNGGHSYCRNPG 366
+C G Y+G ++VT G C W S H +A++ E ++CRNP
Sbjct: 212 QCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVE-----NFCRNPD 266
Query: 367 NQKEAPWCFTLDENFKSDLCDIPAC 391
+E WC+ + CD+ C
Sbjct: 267 GDEEGVWCYVAGKPGDFGYCDLNYC 291
>gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 77.8 bits (190), Expect = 2e-14
Identities = 33/80 (41%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+S G YRGT T +GR CQ W+S PH H+ T ++P +YCRNP +
Sbjct: 27 ECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCSAG 85
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+T D N + + C++ C
Sbjct: 86 PWCYTTDPNVRWEYCNLTRC 105
>gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 77.8 bits (190), Expect = 2e-14
Identities = 33/80 (41%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
+CY+S G YRGT T +GR CQ W+S PH H+ T ++P +YCRNP +
Sbjct: 27 ECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCSAG 85
Query: 372 PWCFTLDENFKSDLCDIPAC 391
PWC+T D N + + C++ C
Sbjct: 86 PWCYTTDPNVRWEYCNLTRC 105
>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
Length = 869
Score = 72.8 bits (177), Expect = 5e-13
Identities = 64/256 (25%), Positives = 96/256 (37%), Gaps = 19/256 (7%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+N+T G LHC +G P PTI W +N V + S + + SRL+ L T
Sbjct: 221 HNVT--FGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQ---LFIT 275
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIGN 184
G + C+ATN ST + P + + G+C YRG C +
Sbjct: 276 KPGLYTCIATNKHGEKFSTAKAAATISIAEWSKP----QKDNKGYCAQYRGEVCNAVLAK 331
Query: 185 RTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKP 244
+ + E Q T +S C A LC++ F C VP P
Sbjct: 332 DALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQEC-SPGVVPTP 390
Query: 245 RDLCRDECEILENVLCQTEYIFARSNP------MILMRLKLPNCEDLPQPESPEAANCIR 298
+CR+ C ++ + C E++ + L +P C LP A C R
Sbjct: 391 IPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTA-CAR 449
Query: 299 IGIPMADPINKNHKCY 314
+P D +N K +
Sbjct: 450 --LPHLDYNKENLKTF 463
Score = 50.1 bits (118), Expect = 4e-06
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 60 LDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIR 119
+ P N+ G A L C GNP P++ W K D+P+ R S + + LRI
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL----RENSRIAVLESGSLRIH 178
Query: 120 NLDTTDTGYFQCVATN 135
N+ D G ++CVA N
Sbjct: 179 NVQKEDAGQYRCVAKN 194
Score = 46.2 bits (108), Expect = 5e-05
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD 122
P+ + + + A C V P P I W +N + R S R G L I +++
Sbjct: 33 PLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN--GQLLTILSVE 90
Query: 123 TTDTGYFQCVATNG-KEVVSSTGVLFVKFGPPPTASP 158
+D G + C A NG V S G L VK P T P
Sbjct: 91 DSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPP 127
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 65.5 bits (158), Expect = 8e-11
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 307 INKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELN---GGHSYCR 363
I+ CY G+ YRGT S +SG +C WNS ++ R + G H+YCR
Sbjct: 121 IDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCR 180
Query: 364 NPGNQKEAPWCFTLDE-NFKSDLCDIPACGK 393
NP ++ PWC+ + S+ C PAC +
Sbjct: 181 NP-DRDSKPWCYVFKAGKYSSEFCSTPACSE 210
Score = 65.5 bits (158), Expect = 8e-11
Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 7/87 (8%)
Query: 310 NHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELN----GGHSYCRNP 365
N CY G YRGT S+T+SG C PWNS +TA + P G H+YCRNP
Sbjct: 212 NSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTA-QNPSAQALGLGKHNYCRNP 270
Query: 366 GNQKEAPWCFTL-DENFKSDLCDIPAC 391
+ PWC L + + CD+P+C
Sbjct: 271 DGDAK-PWCHVLKNRRLTWEYCDVPSC 296
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 65.5 bits (158), Expect = 8e-11
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 307 INKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELN---GGHSYCR 363
I+ CY G+ YRGT S +SG +C WNS ++ R + G H+YCR
Sbjct: 75 IDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCR 134
Query: 364 NPGNQKEAPWCFTLDE-NFKSDLCDIPACGK 393
NP ++ PWC+ + S+ C PAC +
Sbjct: 135 NP-DRDSKPWCYVFKAGKYSSEFCSTPACSE 164
Score = 65.5 bits (158), Expect = 8e-11
Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 7/87 (8%)
Query: 310 NHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELN----GGHSYCRNP 365
N CY G YRGT S+T+SG C PWNS +TA + P G H+YCRNP
Sbjct: 166 NSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTA-QNPSAQALGLGKHNYCRNP 224
Query: 366 GNQKEAPWCFTL-DENFKSDLCDIPAC 391
+ PWC L + + CD+P+C
Sbjct: 225 DGDAK-PWCHVLKNRRLTWEYCDVPSC 250
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 65.1 bits (157), Expect = 1e-10
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 307 INKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPG 366
++ CY+ G+ YRG T SG CQPW S+ + + GGH++CRNP
Sbjct: 211 VDTKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRNVTAEQARNWGLGGHAFCRNPD 270
Query: 367 NQKEAPWCFTLDENFKS-DLCDIPAC 391
N PWCF L+ + S + CD+ C
Sbjct: 271 NDIR-PWCFVLNRDRLSWEYCDLAQC 295
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 62.4 bits (150), Expect = 7e-10
Identities = 31/72 (43%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 307 INKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELN---GGHSYCR 363
I+K+ CY G YRG S GR C PWNS T+ A R L G H+YCR
Sbjct: 47 IDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCR 106
Query: 364 NPGNQKEAPWCF 375
NP N++ PWC+
Sbjct: 107 NPDNRRR-PWCY 117
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 62.4 bits (150), Expect = 7e-10
Identities = 31/72 (43%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 307 INKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELN---GGHSYCR 363
I+K+ CY G YRG S GR C PWNS T+ A R L G H+YCR
Sbjct: 64 IDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCR 123
Query: 364 NPGNQKEAPWCF 375
NP N++ PWC+
Sbjct: 124 NPDNRRR-PWCY 134
>gi|24041012 kringle-containing transmembrane protein 1 isoform 2
precursor [Homo sapiens]
Length = 492
Score = 62.0 bits (149), Expect = 9e-10
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 312 KCYNSTGVDYRGTVSVT--KSGRQCQPWNSQYPHTHTFTALRFPELNGG---HSYCRNPG 366
+C+ + G DYRGT + T + G+ C WN + H + L++P GG H+YCRNP
Sbjct: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETF--QHPYNTLKYPNGEGGLGEHNYCRNPD 90
Query: 367 NQKEAPWCFTL--DENFKSDLCDIPAC 391
+PWC+ ++ C+IPAC
Sbjct: 91 GD-VSPWCYVAEHEDGVYWKYCEIPAC 116
>gi|227116325 kringle-containing transmembrane protein 1 isoform 3
precursor [Homo sapiens]
Length = 458
Score = 62.0 bits (149), Expect = 9e-10
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 312 KCYNSTGVDYRGTVSVT--KSGRQCQPWNSQYPHTHTFTALRFPELNGG---HSYCRNPG 366
+C+ + G DYRGT + T + G+ C WN + H + L++P GG H+YCRNP
Sbjct: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETF--QHPYNTLKYPNGEGGLGEHNYCRNPD 90
Query: 367 NQKEAPWCFTL--DENFKSDLCDIPAC 391
+PWC+ ++ C+IPAC
Sbjct: 91 GD-VSPWCYVAEHEDGVYWKYCEIPAC 116
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 60.1 bits (144), Expect = 3e-09
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
EP +IT + + ++ C+ G PPP+I W+K DA VV+ + FR G L+I L
Sbjct: 313 EPERHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKLTRFRQRNDGG-LQISGL 370
Query: 122 DTTDTGYFQCVATNGK-EVVSSTGVLFVKFGPPPTASP 158
DTG FQC A N EV +ST + P T P
Sbjct: 371 VPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP 408
Score = 42.4 bits (98), Expect = 7e-04
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 7/109 (6%)
Query: 47 NISSELNKDSYLTLDEPMNNITTSL-------GQTAELHCKVSGNPPPTIRWFKNDAPVV 99
N + E+ +YL + NIT G + L C+ SG P P I W K + +
Sbjct: 384 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 443
Query: 100 QEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFV 148
+L + + L I +D G + C+ATN + V ++ L V
Sbjct: 444 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 9/74 (12%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
EP+ G L C G+ P +W N+ R L+ S Y R I +L
Sbjct: 31 EPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNN-------RELTKFSLEY--RYMITSL 81
Query: 122 DTTDTGYFQCVATN 135
D T G+++C+ N
Sbjct: 82 DRTHAGFYRCIVRN 95
>gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken)
[Homo sapiens]
Length = 399
Score = 60.1 bits (144), Expect = 3e-09
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
EP +IT + + ++ C+ G PPP+I W+K DA VV+ + FR G L+I L
Sbjct: 125 EPERHITAEMEKVVDIPCQAKGVPPPSITWYK-DAAVVEVEKLTRFRQRNDGG-LQISGL 182
Query: 122 DTTDTGYFQCVATNGK-EVVSSTGVLFVKFGPPPTASP 158
DTG FQC A N EV +ST + P T P
Sbjct: 183 VPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGP 220
Score = 42.4 bits (98), Expect = 7e-04
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 7/109 (6%)
Query: 47 NISSELNKDSYLTLDEPMNNITTSL-------GQTAELHCKVSGNPPPTIRWFKNDAPVV 99
N + E+ +YL + NIT G + L C+ SG P P I W K + +
Sbjct: 196 NAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILA 255
Query: 100 QEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFV 148
+L + + L I +D G + C+ATN + V ++ L V
Sbjct: 256 SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 304
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 59.7 bits (143), Expect = 4e-09
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 3/136 (2%)
Query: 36 VSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKND 95
+S E+ +S + L++D +P+ N+ + + T L CK++G+ P + WFK+
Sbjct: 4091 ISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDG 4150
Query: 96 APVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPP 154
+ R R++F + L I +D D G F C ATN S+G L V+ P
Sbjct: 4151 KEIAASDRYRIAFVEGT--ASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSF 4208
Query: 155 TASPGYSDEYEEDGFC 170
PG D C
Sbjct: 4209 VTKPGSKDVLPGSAVC 4224
Score = 58.2 bits (139), Expect = 1e-08
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 4/110 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRN 120
EP+ ++ +G+ A L CKV G P I W+K + P ++ F++ + + L I
Sbjct: 7024 EPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNV--ASLVINK 7081
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGP-PPTASPGYSDEYEEDGF 169
+D +D G + C A N V+S+ VL +K PP + D +E GF
Sbjct: 7082 VDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGF 7131
Score = 56.6 bits (135), Expect = 4e-08
Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
Query: 16 LLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTA 75
LL A R A ET LS ++ +I ++L + + M ++TT LG+ A
Sbjct: 30495 LLEATEYEFRVFAENETGLSRPRR----TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAA 30550
Query: 76 ELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
+L C++ G P P I+W++ ++Q R+ S L + + D G + C+ATN
Sbjct: 30551 QLSCQIVGRPLPDIKWYRFGKELIQS-RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATN 30609
Query: 136 GKEVVSSTGVLFVKFGPPPTASPGY 160
V ++ L ++ P PGY
Sbjct: 30610 EVGEVETSSKLLLQ--ATPQFHPGY 30632
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 3/92 (3%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQE-PRRLSFRSTIYGSRLR 117
TL + N+T G++ L C +SG P PT+ W++ D + +++F+S I +RL
Sbjct: 944 TLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLM 1001
Query: 118 IRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
IR D+G F C A N VS++ L V+
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G L C++SG PP + W K D V+ ++ S + + L I NL+ +D G + C
Sbjct: 6472 GSDVILQCEISGTPPFEVVWVK-DRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHC 6530
Query: 132 VATNGKEVVSSTGVLFVKFGPPPTASPGYSD 162
ATN EV S T VKF PP SD
Sbjct: 6531 KATN--EVGSDTCSCSVKFKEPPRFVKKLSD 6559
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+ T L C++SG PP + W+K D ++ ++ S + + + I N+DT+D
Sbjct: 5526 VETLKNAEVSLECELSGTPPFEVVWYK-DKRQLRSSKKYKIASKNFHTSIHILNVDTSDI 5584
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPP 154
G + C A N EV S T V VK PP
Sbjct: 5585 GEYHCKAQN--EVGSDTCVCTVKLKEPP 5610
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 43 TSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEP 102
T S ++S + S++ + ++ LG + L C+VSG+ P ++ WF++ +V P
Sbjct: 6729 TVSVHVSDRIVPPSFI---RKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGP 6785
Query: 103 R-RLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
+ + SF + L + L+ +DTG + CVA N + VL V+ P +P
Sbjct: 6786 KCQSSFSENV--CTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTP 6840
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 48 ISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPV-VQEPRRLS 106
+S EL+ D+ + +P + + GQ C++SG P P I WFKN+ P+ + +S
Sbjct: 33126 LSKELS-DAPAFISQPRSQ-NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSIS 33183
Query: 107 FRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFV 148
+Y L IRN +D+G + A N + S+T L V
Sbjct: 33184 RSRNVYS--LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 48.1 bits (113), Expect = 1e-05
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
G++ +L CK+SG+P + WF+ND+ + + + +SF +++ + L I D+G +
Sbjct: 6379 GESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSV--ALLTINEASAEDSGDYI 6436
Query: 131 CVATNGKEVVSSTGVLFVKFGPPPTASP 158
C A NG S + L VK P T P
Sbjct: 6437 CEAHNGVGDASCSTALTVKAPPVFTQKP 6464
Score = 47.8 bits (112), Expect = 2e-05
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I T G L C++ G PP + W+K D ++ ++ S + + + I N+D D
Sbjct: 7408 IETLKGADVHLECELQGTPPFHVSWYK-DKRELRSGKKYKIMSENFLTSIHILNVDAADI 7466
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSD 162
G +QC ATN +V S T V + PP SD
Sbjct: 7467 GEYQCKATN--DVGSDTCVGSIALKAPPRFVKKLSD 7500
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+ +LG A+ C++ P +WFK + E + S RS+ Y S L I D
Sbjct: 3465 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDC 3523
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPT 155
G + C A+N VS T L V PPT
Sbjct: 3524 GEYTCKASNEYGSVSCTATLTVTEAYPPT 3552
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
G +L CKV+G PP I WF ND + + + R+SF + + LR+ ++ D+G +
Sbjct: 4314 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVEST--AVLRLTDVGIEDSGEYM 4371
Query: 131 CVATNGKEVVSSTGVLFVKFGP 152
C A N + ++ VK P
Sbjct: 4372 CEAQNEAGSDHCSSIVIVKESP 4393
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 3/92 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPV-VQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
G +L C V+G+ P +I+WFK+D + E + SF + L I L+ TD+G +
Sbjct: 4689 GSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNT--AFLEISQLEGTDSGTYT 4746
Query: 131 CVATNGKEVVSSTGVLFVKFGPPPTASPGYSD 162
C ATN +G L VK P P D
Sbjct: 4747 CSATNKAGHNQCSGHLTVKEPPYFVEKPQSQD 4778
Score = 45.4 bits (106), Expect = 9e-05
Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 13/135 (9%)
Query: 35 SVSAELVPTSSWNISSELNKDSYLTL---DEPMNNIT-------TSLGQTAELHCKVSGN 84
SV A + ++++++ DS T+ EP + G ++ L CK++G+
Sbjct: 5391 SVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGS 5450
Query: 85 PPPTIRWFKNDAPV-VQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSST 143
P + WF+N+ + + R++F ++ + +++ NL T D+G F C A N S +
Sbjct: 5451 PEIRVVWFRNEHELPASDKYRMTFIDSV--AVIQMNNLSTEDSGDFICEAQNPAGSTSCS 5508
Query: 144 GVLFVKFGPPPTASP 158
+ VK P ++ P
Sbjct: 5509 TKVIVKEPPVFSSFP 5523
Score = 45.1 bits (105), Expect = 1e-04
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 76 ELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
EL C+V+G PP + W KN+ ++ ++ + + L I D +DTG +QC+ +N
Sbjct: 4973 ELECEVTGTPPFEVTWLKNNRE-IRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN 5031
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 1/109 (0%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRI 118
+L P N + G+ ++ V G P P I W K+ P +++ R++ T + L I
Sbjct: 24313 SLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEP-LKQTTRVNVEETATSTVLHI 24371
Query: 119 RNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
+ + D G + ATN + + V P P P DE D
Sbjct: 24372 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSAD 24420
Score = 44.3 bits (103), Expect = 2e-04
Identities = 23/64 (35%), Positives = 33/64 (51%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
GQ+ +VSG PPPT++W K+ P+ P + L IR+ DTGY++
Sbjct: 31809 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 31868
Query: 132 VATN 135
ATN
Sbjct: 31869 TATN 31872
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
LG + + CKVSG+ P + +WFK D + + L + NL+ DT +
Sbjct: 5250 LGSSIHMECKVSGSLPISAQWFK-DGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYT 5308
Query: 131 CVATNGKEVVSSTGVLFVKFGPPPTASPG 159
C +N + +G+L VK P PG
Sbjct: 5309 CKVSNVAGDDACSGILTVKEPPSFLVKPG 5337
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLD 122
+ N LG + L CKV+G+ P ++ WF +V + + +F + L++ +LD
Sbjct: 5806 LKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNV--CTLQLNSLD 5863
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
++D G + CVA N VL V+ P P
Sbjct: 5864 SSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEP 5899
Score = 42.7 bits (99), Expect = 6e-04
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPV-VQEPRRLSFRSTIYGSRLRIRNLDTTD 125
+ S+G +A L C+++G P + W+K D + ++ FR+ + + L +D D
Sbjct: 7970 VKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNV--ATLVFNQVDIND 8027
Query: 126 TGYFQCVATNG-KEVVSSTGVLFVKFGPPPTASPGYSDEYEEDG 168
+G + C A N EV +ST + + PP+ S D E G
Sbjct: 8028 SGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVG 8071
Score = 42.7 bits (99), Expect = 6e-04
Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 47 NISSELNKDSYLTLDEP---------MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAP 97
N E++ ++LT+ E + ++ ++G C +SG+ P ++ W+K+ P
Sbjct: 8037 NSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKP 8096
Query: 98 VVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPP 154
+ P + SF + L I D + G + C ATN SS+ L + G P
Sbjct: 8097 LKDSPNVQTSFLDNT--ATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNP 8152
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 2/144 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
GQ V P ++W+ N + QE ++ + +T L I + T D+G ++
Sbjct: 32388 GQNTRFILNVQSKPTAEVKWYHNGVEL-QESSKIHYTNTSGVLTLEILDCHTDDSGTYRA 32446
Query: 132 VATNGKEVVSSTGVLFVKFGPPPT-ASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYME 190
V TN K S L V G T AS +E F + R A A +T ME
Sbjct: 32447 VCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEME 32506
Query: 191 SLHMQGEIENQITAAFTMIGTSSH 214
+ E+++Q+T + + H
Sbjct: 32507 ASSSVREVKSQMTETRESLSSYEH 32530
Score = 42.4 bits (98), Expect = 7e-04
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVV-QEPRRLSFRSTIYGSRLRIRN 120
E +T ++G+T L CKV+G P ++ W+K+ + + + SF + I S LRI +
Sbjct: 5708 EKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKI--SSLRILS 5765
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFV 148
++ D G + N S T V+ V
Sbjct: 5766 VERQDAGTYTFQVQNNVGKSSCTAVVDV 5793
Score = 42.4 bits (98), Expect = 7e-04
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 50 SELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFR 108
S L ++T EP+ ++G + L C+V+G P T+ W+K D + P R F
Sbjct: 6074 STLEPPYFVTELEPLE---AAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFT 6130
Query: 109 STIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
+ + + L ++ D+G + C A N SS V ++
Sbjct: 6131 NNV--ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQ 6169
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR----RLSFRSTIYGS 114
T +P+ ++ G TA +SG P P + WF+ D V+ ++SF +
Sbjct: 7 TFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR-DGQVISTSTLPGVQISFSDG--RA 63
Query: 115 RLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGY 160
+L I + ++G + ATNG +ST L VK TA P +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK---AETAPPNF 106
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/185 (22%), Positives = 73/185 (39%), Gaps = 28/185 (15%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLR 117
T+ E +I + G T L C V+G P + +WFK+ + + + ++SF + + G L+
Sbjct: 7587 TIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG--LK 7644
Query: 118 IRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIA 177
I N+ +D+G + N S T L V T P ++ + +E +
Sbjct: 7645 IINVAPSDSGVYSFEVQNPVGKDSCTASLQVS---DRTVPPSFTRKLKETNGLSGSSVVM 7701
Query: 178 CARFIGNRTVYMESLHMQGEI----------------------ENQITAAFTMIGTSSHL 215
+ G+ + + H EI E + +T I T+
Sbjct: 7702 ECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAG 7761
Query: 216 SDKCS 220
SD+CS
Sbjct: 7762 SDECS 7766
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 6/95 (6%)
Query: 56 SYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGS 114
S++ +PM+ +T G V G PP ++ WFK + +V R +S ++ +
Sbjct: 7776 SFVQKPDPMDVLT---GTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSV--A 7830
Query: 115 RLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
L + ++DT+ +G + C+ +N S T L++K
Sbjct: 7831 ELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 1/103 (0%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
N T G+ ++ G P P + W K++ P +++ R++ ST S L I++
Sbjct: 22155 NTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVP-LKQTTRVNAESTENNSLLTIKDACRE 22213
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
D G++ TN T + V P P P DE D
Sbjct: 22214 DVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTAD 22256
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 7/118 (5%)
Query: 32 TELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRW 91
TE +V+ + P + ISS+ + + + T S A+ K +G P PT W
Sbjct: 32832 TESTVTRKTEPKAPEPISSKP------VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIW 32885
Query: 92 FKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
K D + + + G L I DT+D+G + C N VSS+ L +K
Sbjct: 32886 TK-DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 32942
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 6/95 (6%)
Query: 56 SYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGS 114
S++ EP+ + G+ + G PP + WF+ +V+ R + F T+ +
Sbjct: 5894 SFVKEPEPLEVLP---GKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTV--A 5948
Query: 115 RLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
L + N+D + +G + CV +N S T LFVK
Sbjct: 5949 ELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 5983
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Query: 79 CKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGK 137
CK+ G+P + W+K++ + + + R+SF ++ + L + NL D+G + C A N
Sbjct: 7327 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSV--AVLEMHNLSVEDSGDYTCEAHNAA 7384
Query: 138 EVVSSTGVLFVKFGP 152
SS+ L VK P
Sbjct: 7385 GSASSSTSLKVKEPP 7399
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 1/101 (0%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+ G ++ V G P PT+ W K D ++++ +R++F +T + L I +D+
Sbjct: 21075 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATSTILNINECVRSDS 21133
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
G + A N V + V P P P DE D
Sbjct: 21134 GPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 21174
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 8/127 (6%)
Query: 31 ETELSVSAE-LVPTSSWN-ISSELNKDSYLTLDEP-----MNNITTSLGQTAELHCKVSG 83
E E V E L S W+ IS + S + + P + N+ A L CKV+G
Sbjct: 30894 EYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTG 30953
Query: 84 NPPPTIRWFKNDAPVVQEPRRLSFRSTIYG-SRLRIRNLDTTDTGYFQCVATNGKEVVSS 142
+P P ++W++ ++ + + + G +L I ++ D +Q ATN VS
Sbjct: 30954 HPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSG 31013
Query: 143 TGVLFVK 149
T L V+
Sbjct: 31014 TASLEVE 31020
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLD 122
+ N TT L +A V+G+PP +I W K+D + ++ +SF ++ + L+IR++D
Sbjct: 5054 IENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSV--ATLQIRSVD 5111
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVK 149
+G + C A N V L V+
Sbjct: 5112 NGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 1/103 (0%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD 122
P I G+ EL ++G PPP WF + ++E R++ + ++L IR
Sbjct: 29744 PQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSK-LRESERVTVETHTKVAKLTIRETT 29802
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYE 165
DTG + N S T + + P P P DE +
Sbjct: 29803 IRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 29845
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G++A LHCK+ G+P + WFKN+ + E + + L I ++ D+G + C
Sbjct: 3752 GESARLHCKLKGSPVIQVTWFKNNKE-LSESNTVRMYFVNSEAILDITDVKVEDSGSYSC 3810
Query: 132 VATNGKEVVSSTGVLFVKFGP 152
A N S + + +K P
Sbjct: 3811 EAVNDVGSDSCSTEIVIKEPP 3831
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I G + VSG PPPT+ W N+ + P+ + +T S + I+N +
Sbjct: 16532 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL---PQEATIETTAISSSMVIKNCQRS 16588
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
G + +A N T ++ V P P +P
Sbjct: 16589 HQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP 16622
Score = 40.0 bits (92), Expect = 0.004
Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
D+ + +T S G+ +L C V G+ P I+W K ++ R SF + L +R+
Sbjct: 8349 DQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE-IKPSDRCSFSFASGTAVLELRD 8407
Query: 121 LDTTDTGYFQCVATN 135
+ D+G + C A+N
Sbjct: 8408 VAKADSGDYVCKASN 8422
Score = 40.0 bits (92), Expect = 0.004
Identities = 20/62 (32%), Positives = 32/62 (51%)
Query: 74 TAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVA 133
TA KV G+P P ++W K + + R+ ++L IR+ TD+G ++CVA
Sbjct: 8470 TATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVA 8529
Query: 134 TN 135
N
Sbjct: 8530 FN 8531
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I G++ ++ + G P PTI+W K D + RL +ST + + L +++
Sbjct: 22551 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQE-LSNTARLEIKSTDFATSLSVKDAVRV 22609
Query: 125 DTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
D+G + A N G+ V+ + + GPP
Sbjct: 22610 DSGNYILKAKNVAGERSVTVNVKVLDRPGPP 22640
Score = 39.7 bits (91), Expect = 0.005
Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 9/113 (7%)
Query: 47 NISSELNKDSYLTLDEPMNNITTSLGQ------TAELHCKVSGNPPPTIRWFKNDAPVVQ 100
N++ + LT+ EP + + Q T E + G PP I+WFK+D +V
Sbjct: 5313 NVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVS 5372
Query: 101 EPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGP 152
P+ + + S L + ++D + TG + C TN S T +L V P
Sbjct: 5373 GPKCFIGLEGST--SFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPP 5423
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
+G T L + G P P + W K D P + T GS+L IRN D G +
Sbjct: 17232 VGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVTPVGSKLEIRNAAHEDGGIYS 17288
Query: 131 CVATN--GKEVVSSTGVLFVKFGPP 153
N G + VS ++ K GPP
Sbjct: 17289 LTVENPAGSKTVSVKVLVLDKPGPP 17313
Score = 38.5 bits (88), Expect = 0.011
Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVV--QEPRRLSFRSTIYGSRLRIRN 120
P+ N T +G+ ++ +P P + W+K+ + ++ +F S +L I +
Sbjct: 31695 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 31754
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTAS 157
+ T D + VA N S L V PPPT S
Sbjct: 31755 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDS 31791
Score = 38.1 bits (87), Expect = 0.014
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 5/102 (4%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIR 119
D + N G HCK+SG P P I W+K+ + R ++ F S LRI
Sbjct: 1294 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS-LRIP 1352
Query: 120 NLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP---PTASP 158
+ D G + A+N K +G L+V+ P PT P
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1394
Score = 38.1 bits (87), Expect = 0.014
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 1/92 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT G+ + V G P PT +W K + VV L+ S L I+++ D+
Sbjct: 18908 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS-SHLAVHKADSSSILIIKDVTRKDS 18966
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
GY+ A N + + V P P P
Sbjct: 18967 GYYSLTAENSSGTDTQKIKVVVMDAPGPPQPP 18998
Score = 38.1 bits (87), Expect = 0.014
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I + G+T L V G P PTI W + D ++E R ++T + + L +++
Sbjct: 23633 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKE-IEESARCEIKNTDFKALLIVKDAIRI 23691
Query: 125 DTGYFQCVATN 135
D G + A+N
Sbjct: 23692 DGGQYILRASN 23702
Score = 38.1 bits (87), Expect = 0.014
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I G+T L + G P P + W K+ + + R+ +STI + L +++ TD
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + +N G + + T + + GPP
Sbjct: 24777 GQYILKLSNVGGTKSIPITVKVLDRPGPP 24805
Score = 38.1 bits (87), Expect = 0.014
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
++T G++A C G P PT+ W + V+ R +T Y S I ++ +D
Sbjct: 32569 SMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARHQVTTTKYKSTFEISSVQASD 32627
Query: 126 TGYFQCVATNGK 137
G + V N +
Sbjct: 32628 EGNYSVVVENSE 32639
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKN-DAPVVQEPRRLSFRSTIYGSRLRIRN 120
E + N+ G E+ + +GNP P I W KN D V + ++ T + L+I +
Sbjct: 1560 EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1619
Query: 121 LDTTDTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
+ D+ ++ A N G++ + V+F P
Sbjct: 1620 TVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1654
Score = 37.4 bits (85), Expect = 0.024
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 6/86 (6%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRN 120
P+ + TS GQ A C+VSG + W+ D + +P R FR T + +L I
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKI--KPSRF-FRMTQFEDTYQLEIAE 3405
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVL 146
D G + VA+N VSST L
Sbjct: 3406 AYPEDEGTYTFVASNAVGQVSSTANL 3431
Score = 37.4 bits (85), Expect = 0.024
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 17/125 (13%)
Query: 31 ETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNN---------ITTSLGQTAELHCKV 81
+T+LS S + ++S N + + LT EP + I G++A+ C V
Sbjct: 6236 QTDLSHSGQYSCSAS-NPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHV 6294
Query: 82 SGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRNLDTTDTGYFQCVATN--GK 137
+G P I W K++ + ++ T G+ LRI + D+G + C ATN GK
Sbjct: 6295 TGAQPMRITWSKDNKEIRPGG---NYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGK 6351
Query: 138 EVVSS 142
++ S+
Sbjct: 6352 DMCSA 6356
Score = 37.4 bits (85), Expect = 0.024
Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
+G++A+ C V+G P + W K D+ ++ + + L + +D D+G +
Sbjct: 8166 VGESADFECHVTGTQPIKVSWAK-DSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 8224
Query: 131 CVATNGKEVVSSTGVLFVKFG-PPPTASPGYSDEYEE 166
C A N S T L +K PP+ + S+ EE
Sbjct: 8225 CYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEE 8261
Score = 37.4 bits (85), Expect = 0.024
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ + G+ L VSG PPPT+ W K D ++ +L + + + L ++
Sbjct: 21469 DTVILKAGEAFRLEADVSGRPPPTMEWSK-DGKELEGTAKLEIKIADFSTNLVNKDSTRR 21527
Query: 125 DTGYFQCVATN 135
D+G + ATN
Sbjct: 21528 DSGAYTLTATN 21538
Score = 37.4 bits (85), Expect = 0.024
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
++ + +GQ ++ +SG P PTI W K+ P +++ R++ ++ + L I+
Sbjct: 23237 SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLP-LKQTTRINVTDSLDLTTLSIKETHKD 23295
Query: 125 DTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
D G + N G++ S V K PP
Sbjct: 23296 DGGQYGITVANVVGQKTASIEIVTLDKPDPP 23326
Score = 37.4 bits (85), Expect = 0.024
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G + +L +SG P PTI W+K+D +Q + +T + + I++ D ++G ++
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKE-LQTNALVCVENTTDLASILIKDADRLNSGCYEL 26945
Query: 132 VATNGKEVVSSTGVLFVKFGPPPTASP 158
N S+T + + P P P
Sbjct: 26946 KLRNAMGSASATIRVQILDKPGPPGGP 26972
Score = 37.0 bits (84), Expect = 0.031
Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 7/115 (6%)
Query: 44 SSWNISSELNKDSYLTLDEPMNNITTSLGQTA------ELHCKVSGNPPPTIRWFKNDAP 97
S+ N + +LT+ EP + Q +L V G P TI+WFK++
Sbjct: 4748 SATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE 4807
Query: 98 VVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGP 152
+ R ++ + L + TD+G + C +N +S LFVK P
Sbjct: 4808 LHSGAARSVWKDDT-STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPP 4861
Score = 37.0 bits (84), Expect = 0.031
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT +GQT + +V G P P I W K +V+E +R+ + L+I+ D
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE-KRVDLIQDLPRVELQIKEAVRADH 17976
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPP 154
G + A N + ++ V P P
Sbjct: 17977 GKYIISAKNSSGHAQGSAIVNVLDRPGP 18004
Score = 36.6 bits (83), Expect = 0.040
Identities = 26/110 (23%), Positives = 47/110 (42%), Gaps = 9/110 (8%)
Query: 47 NISSELNKDSYLTLDEPMN------NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQ 100
N++ + LT+ EP + ++ G + + G PP ++WFK +V
Sbjct: 6817 NVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVP 6876
Query: 101 -EPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
E +S + + L + + ++G + C+ TN S T LFVK
Sbjct: 6877 GESCNISLEDFV--TELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924
Score = 36.6 bits (83), Expect = 0.040
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ +T +G+ L + SG P P + WFK++A V+++ R ++T L +
Sbjct: 16826 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDD-RTHIKTTPATLALEKIKAKRS 16884
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
D+G + V N + V P P P DE +D
Sbjct: 16885 DSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 51 ELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRS 109
E K + EP+ + G+TA C+V+G P P + W+ N + + R R+ +
Sbjct: 1837 EKQKPDIVLYPEPVRVLE---GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893
Query: 110 TIYGSRLRIRNLDTTDTGYFQCVATNGKEVV 140
Y L I + + DTG + A N + V+
Sbjct: 1894 IHY---LDIVDCKSYDTGEVKVTAENPEGVI 1921
Score = 36.2 bits (82), Expect = 0.053
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G A L C+VSG P I WFK D ++ ++ S L I + ++ D G ++C
Sbjct: 3845 GTNALLQCEVSGTGPFEISWFK-DKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYEC 3903
Query: 132 VATN 135
V N
Sbjct: 3904 VVAN 3907
Score = 36.2 bits (82), Expect = 0.053
Identities = 19/85 (22%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+ ++ +LG C+++G+ P + W+K D ++++ L + L+I D
Sbjct: 7122 LKDVHETLGFPVAFECRINGSEPLQVSWYK-DGVLLKDDANLQTSFVHNVATLQILQTDQ 7180
Query: 124 TDTGYFQCVATNGKEVVSSTGVLFV 148
+ G + C A+N SS+ L +
Sbjct: 7181 SHIGQYNCSASNPLGTASSSAKLIL 7205
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+T G EL V+G P P I W K D ++++ +R++ + S + I + +DT
Sbjct: 13700 LTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVPKKSTVTIVDSKRSDT 13758
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + A N G+ + K GPP
Sbjct: 13759 GTYIIEAVNVCGRATAVVEVNVLDKPGPP 13787
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G T L+ V G PPP I W K + +++ L +ST + + LR N++ D G +
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVN-LRDRIGLDIKSTDFDTFLRCENVNKYDAGKYIL 19766
Query: 132 VATN--GKEVVSSTGVLFVKFGPP 153
N GK+ + + GPP
Sbjct: 19767 TLENSCGKKEYTIVVKVLDTPGPP 19790
Score = 35.8 bits (81), Expect = 0.069
Identities = 18/85 (21%), Positives = 35/85 (41%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+N++T G+ AEL + G P ++W K V++E + + L+ +
Sbjct: 5616 LNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEP 5675
Query: 124 TDTGYFQCVATNGKEVVSSTGVLFV 148
+ G + C N + + L V
Sbjct: 5676 ANAGKYICQIKNDGGMRENMATLMV 5700
Score = 35.8 bits (81), Expect = 0.069
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
D P +T +G L G P P+I W K+ P ++E + F T L I+N
Sbjct: 27567 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLP-LKESEFVRFSKTENKITLSIKN 27625
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP 153
G + + N + + + + GPP
Sbjct: 27626 AKKEHGGKYTVILDNAVCRI-AVPITVITLGPP 27657
Score = 35.4 bits (80), Expect = 0.090
Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 4/95 (4%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+ +I ++G L C+++G+ P + W++ D ++++ L + L+I D
Sbjct: 6181 LKDIEQTVGLPVTLTCRLNGSAPIQVCWYR-DGVLLRDDENLQTSFVDNVATLKILQTDL 6239
Query: 124 TDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
+ +G + C A+N SS+ L + P SP
Sbjct: 6240 SHSGQYSCSASNPLGTASSSARLTAR---EPKKSP 6271
Score = 35.0 bits (79), Expect = 0.12
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTT 124
++TT +G+ A+ C V+G P W K+ A + P R+S + L + NL
Sbjct: 3559 SLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKH--ILELSNLTIQ 3616
Query: 125 DTGYFQCVATN 135
D G + C A+N
Sbjct: 3617 DRGVYSCKASN 3627
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I G+ +++ ++G P P I W K D ++E R ST + L +++ DT
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDT 25857
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + N G V+ + K GPP
Sbjct: 25858 GQYVLTLKNVAGTRSVAVNCKVLDKPGPP 25886
Score = 35.0 bits (79), Expect = 0.12
Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
++ G+ ++ G PPPT+ W K++ + + R S +T S L I + D
Sbjct: 27280 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 27338
Query: 126 TGYFQCVATNG 136
TG + NG
Sbjct: 27339 TGKYILTIENG 27349
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
D+ +T G + L VSG PPP I W K + R +T S L +
Sbjct: 29450 DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS---RAIIDTTESYSLLIVDK 29506
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTAS 157
++ D G + A N S+T ++ V P P S
Sbjct: 29507 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS 29543
Score = 34.7 bits (78), Expect = 0.15
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G L G+ P TIRWFK + +V + + S L + + T+D+G + C
Sbjct: 4220 GSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESS-LELYLVKTSDSGTYTC 4278
Query: 132 VATNGKEVVSSTGVLFVK 149
+N V + LFVK
Sbjct: 4279 KVSNVAGGVECSANLFVK 4296
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 3/140 (2%)
Query: 28 AAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNI-TTSLGQTAELHCKVSGNPP 86
A T +++S P+ I +E N + L M ++ T G L V G P
Sbjct: 19266 AIARTAVNISPPSEPSDPVTILAE-NVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 19324
Query: 87 PTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVL 146
PT+ W K D +++ + L + +++ D+G + A N S+T L
Sbjct: 19325 PTVSW-KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKL 19383
Query: 147 FVKFGPPPTASPGYSDEYEE 166
V P P AS + Y +
Sbjct: 19384 KVLDKPGPPASVKINKMYSD 19403
Score = 34.3 bits (77), Expect = 0.20
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
GQT L V G+ P ++ W K + ++ + ++SF + + + L I ++ + G +
Sbjct: 3938 GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGV--AVLIIPDVQISFGGKYT 3995
Query: 131 CVATNGKEVVSSTGVLFVK 149
C+A N +S G L VK
Sbjct: 3996 CLAENEAGSQTSVGELIVK 4014
Score = 34.3 bits (77), Expect = 0.20
Identities = 15/72 (20%), Positives = 36/72 (50%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+++I+T +G+ +L + G P ++ WFK+ +V+E + + + L+ ++
Sbjct: 7498 LSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEP 7557
Query: 124 TDTGYFQCVATN 135
+ G + C N
Sbjct: 7558 ANAGKYTCQIKN 7569
Score = 34.3 bits (77), Expect = 0.20
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 29 AQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPT 88
AQ ELS +A+L L D Y T+ +++ T L C+VS + P
Sbjct: 11645 AQVKELSSTAQL---------KVLEADPYFTVK--LHDKTAVEKDEITLKCEVSKDVP-- 11691
Query: 89 IRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
++WFK+ +V P + S ++ L+I+ D D G + C
Sbjct: 11692 VKWFKDGEEIVPSP-KYSIKADGLRRILKIKKADLKDKGEYVC 11733
Score = 34.3 bits (77), Expect = 0.20
Identities = 46/216 (21%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 54 KDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYG 113
K + L P+ ++T + G+TA C++S P + W+ ++ ++ RS
Sbjct: 12192 KPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLK-GKKLEPSDKVVPRSEGKV 12249
Query: 114 SRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGF---- 169
L +R++ D G Q A + K + LFVK PP + D+ E+G
Sbjct: 12250 HTLTLRDVKLEDAGEVQLTAKDFKTHAN----LFVK-EPPVEFTKPLEDQTVEEGATAVL 12304
Query: 170 -CQPYRGIACARFIGNRTVYMES----LHMQGEIENQITAAFTMIGTSSHLSD------K 218
C+ R A ++ N T ++S + G + + T ++ D
Sbjct: 12305 ECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTS 12364
Query: 219 CSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEI 254
C+ +P + P T + +++ R ECE+
Sbjct: 12365 CNLNVVPPHVEFLRPL---TDLQVREKEMARFECEL 12397
Score = 33.9 bits (76), Expect = 0.26
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 77 LHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNG 136
L +V+G PP I WFK D +++ R+ + L+I D G +QC TN
Sbjct: 4412 LLAEVAGTPPFEITWFK-DNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTN- 4469
Query: 137 KEVVSSTGVLFVKFGPPPT 155
EV SS V PP+
Sbjct: 4470 -EVGSSICSARVTLREPPS 4487
Score = 33.9 bits (76), Expect = 0.26
Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 17/118 (14%)
Query: 33 ELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWF 92
+L++ L+P S SE T++E + G + +L +V+G+ P T+ W+
Sbjct: 8239 QLNIKERLIPPSFTKRLSE-------TVEE-------TEGNSFKLEGRVAGSQPITVAWY 8284
Query: 93 KNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
KN+ + ++F++ L++R D G + C +N T + +K
Sbjct: 8285 KNNIEIQPTSNCEITFKNNTL--VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340
Score = 33.5 bits (75), Expect = 0.34
Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTD 125
I + G A L V+G P +W+K+ P+V + R+SF++ + ++L+ + + D
Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNV--AQLKFYSAELHD 4083
Query: 126 TGYFQCVATNGKEVVSST 143
+G + +N EV SS+
Sbjct: 4084 SGQYTFEISN--EVGSSS 4099
Score = 33.5 bits (75), Expect = 0.34
Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKN-DAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
+T G T L V G P P + W K+ DA + R+ + S+ + +D
Sbjct: 18211 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSD 18270
Query: 126 TGYFQCVATN--GKEVVSSTGVLFVKFGP 152
G + ATN G V +T + K GP
Sbjct: 18271 GGKYVVTATNTAGSFVAYATVNVLDKPGP 18299
Score = 33.1 bits (74), Expect = 0.45
Identities = 30/126 (23%), Positives = 50/126 (39%), Gaps = 20/126 (15%)
Query: 26 GAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNP 85
G A EL V AE P + + + ++T G L +V+G P
Sbjct: 87 GQATSTAELLVKAETAPPN---------------FVQRLQSMTVRQGSQVRLQVRVTGIP 131
Query: 86 PPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRNLDTTDTGYFQCVATNGKEVVSST 143
P ++++++ A + L F+ + G L I D+G + ATN +ST
Sbjct: 132 TPVVKFYRDGAEIQSS---LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATST 188
Query: 144 GVLFVK 149
L V+
Sbjct: 189 AELLVQ 194
Score = 33.1 bits (74), Expect = 0.45
Identities = 33/143 (23%), Positives = 53/143 (37%), Gaps = 5/143 (3%)
Query: 7 RGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNN 66
R T+ LL L + A A+E ++++ + S E K + E + +
Sbjct: 2032 RKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPK-----IFERIQS 2086
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
T G A +V G P P W+KN + + R + L IR++ D+
Sbjct: 2087 QTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDS 2146
Query: 127 GYFQCVATNGKEVVSSTGVLFVK 149
A N SS L V+
Sbjct: 2147 ASIMVKAINIAGETSSHAFLLVQ 2169
Score = 33.1 bits (74), Expect = 0.45
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+ + G T + G P PT +W D ++ + + + S L I+N
Sbjct: 17517 IEGLVVKAGTTVRFPAIIRGVPVPTAKW-TTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 17575
Query: 124 TDTGYFQCVATN---GKEVVSSTGVLFVKFGPP 153
DTG +Q +N K V VL V GPP
Sbjct: 17576 RDTGEYQITVSNAAGSKTVAVHLTVLDVP-GPP 17607
Score = 33.1 bits (74), Expect = 0.45
Identities = 21/97 (21%), Positives = 42/97 (43%), Gaps = 3/97 (3%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRI 118
+++ P + + ++ G P T+ W K D ++E R++ S+ + L I
Sbjct: 25396 SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRK-DGQTLKETTRVNVSSSKTVTSLSI 25454
Query: 119 RNLDTTDTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
+ D G ++ +N G V T ++ + GPP
Sbjct: 25455 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP 25491
Score = 32.7 bits (73), Expect = 0.58
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 32/144 (22%)
Query: 60 LDEPMNNITTSL----GQTAELHCKVSGNPPPTIRWFKND------------APVV---- 99
+D P + TSL G L +SG+P PTI W K++ AP+V
Sbjct: 14678 IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRK 14737
Query: 100 -----QEP------RRLSFRSTIYG-SRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLF 147
+EP +RLS ++ G S+LR+R+ D G + N + + +
Sbjct: 14738 GEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVS 14797
Query: 148 VKFGPPPTASPGYSDEYEEDGFCQ 171
V P P + + D + C+
Sbjct: 14798 VLDTPGPPINFVFEDIRKTSVLCK 14821
Score = 32.0 bits (71), Expect = 0.99
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 8/105 (7%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+N+ + G+ L +G PP ++ W KN V +R + +T + L I +
Sbjct: 7874 LNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPS-QRCNITTTEKSAILEIPSSTV 7932
Query: 124 TDTGYFQCVATN--GKEVVSSTGVL-----FVKFGPPPTASPGYS 161
D G + C N GK+ S+ ++ FVK P S G S
Sbjct: 7933 EDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDS 7977
Score = 31.2 bits (69), Expect = 1.7
Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
G + C+V GNP P + W K+ P+ R ++S+ +L I D G +
Sbjct: 1096 GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYT 1155
Query: 131 CVATNGKEVVSSTGVL 146
V N S++ L
Sbjct: 1156 IVVRNKHGETSASASL 1171
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRN 120
P+ ++ G A L CKVS +++W+ ND + + R ++ + G+ RL I
Sbjct: 2450 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR---VQAIVKGTKQRLVINR 2506
Query: 121 LDTTDTGYFQCV 132
+D G ++ +
Sbjct: 2507 THASDEGPYKLI 2518
Score = 31.2 bits (69), Expect = 1.7
Identities = 26/119 (21%), Positives = 43/119 (36%), Gaps = 8/119 (6%)
Query: 51 ELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRST 110
EL+ DS L I G +A +H G P P I W + + ++
Sbjct: 24023 ELDLDSELR-----KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD---KVQIEKG 24074
Query: 111 IYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGF 169
+ ++L I N D D G + N S+ + V P P + + ++ F
Sbjct: 24075 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAF 24133
Score = 30.8 bits (68), Expect = 2.2
Identities = 23/105 (21%), Positives = 41/105 (39%), Gaps = 2/105 (1%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD 122
P + + G ++ +SG P P + ++ P ++ R + T + ++
Sbjct: 26482 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVP-LKATMRFNTEITAENLTINLKESV 26540
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGP-PPTASPGYSDEYEE 166
T D G ++ A N + + V P PPT SD EE
Sbjct: 26541 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEE 26585
Score = 30.4 bits (67), Expect = 2.9
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT G + +SG P P + W K + ++E R+S +T + L +++ D+
Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTW-KLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDS 28715
Query: 127 G-YFQCVA-TNGKEVVSSTGVLFVKFGP 152
G YF + T G + S T V+ + GP
Sbjct: 28716 GRYFLTLENTAGVKTFSVTVVVIGRPGP 28743
Score = 30.0 bits (66), Expect = 3.8
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
+G +A C VS + T W K+ + + + P+ F + +L I ++ +D G +
Sbjct: 11132 VGSSAIFECLVSPSTAITT-WMKDGSNIRESPKH-RFIADGKDRKLHIIDVQLSDAGEYT 11189
Query: 131 CVATNGKEVVSSTGVLFVK 149
CV G + +ST L V+
Sbjct: 11190 CVLRLGNKEKTSTAKLVVE 11208
Score = 29.6 bits (65), Expect = 4.9
Identities = 22/97 (22%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
+ + +T G+ A +SG P P I W+K + ++ + F L +
Sbjct: 3243 QELQPVTVQSGKPARFCAVISGRPQPKISWYKEE-QLLSTGFKCKFLHDGQEYTLLLIEA 3301
Query: 122 DTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
D + C A N V +++ L V+ P SP
Sbjct: 3302 FPEDAAVYTCEAKNDYGVATTSASLSVEV--PEVVSP 3336
Score = 29.6 bits (65), Expect = 4.9
Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G + L G P PT W K D+ + R +T S L + N + D G +
Sbjct: 28372 GASIRLFIAYQGRPTPTAVWSKPDSNL---SLRADIHTTDSFSTLTVENCNRNDAGKYTL 28428
Query: 132 VATN--GKEVVSSTGVLFVKFGPP 153
N G + ++ T + GPP
Sbjct: 28429 TVENNSGSKSITFTVKVLDTPGPP 28452
Score = 29.6 bits (65), Expect = 4.9
Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 70 SLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD-TTDTGY 128
++G T LH G P P + WF + ++Q ++ +T + + L ++N+ T G
Sbjct: 30641 AVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK 30699
Query: 129 FQCVATN 135
++ +N
Sbjct: 30700 YKVQLSN 30706
Score = 29.3 bits (64), Expect = 6.4
Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLR 117
T+ E +I + G A L K SG T +WFK+ + + ++S T+ S L+
Sbjct: 4580 TITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTV--SILK 4637
Query: 118 IRNLDTTDTGYF 129
I + + D+G +
Sbjct: 4638 IISTEKKDSGEY 4649
Score = 29.3 bits (64), Expect = 6.4
Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 15/117 (12%)
Query: 32 TELSVSAELVPTSSWNISSELNKDS-------YLTLDEP------MNNITTSLGQTAELH 78
TEL + E+ P S + S + D+ +L + EP + + + G L
Sbjct: 6889 TELELF-EVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLE 6947
Query: 79 CKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
+G PP ++ W K D ++ + R S T + L I D + C+ N
Sbjct: 6948 ATYTGTPPISVSWIK-DEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIEN 7003
Score = 29.3 bits (64), Expect = 6.4
Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIY--GSRLRIRNLDT 123
++ +LG++ C V+G P I W K++ + +++ T+ + L + +
Sbjct: 7220 SVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGG---NYKMTLVENTATLTVLKVGK 7276
Query: 124 TDTGYFQCVATN--GKEVVSS 142
D G + C A+N GK+ S+
Sbjct: 7277 GDAGQYTCYASNIAGKDSCSA 7297
Score = 29.3 bits (64), Expect = 6.4
Identities = 14/59 (23%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 77 LHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
L + G P P++ W K + P+ + R+S S+ + L + + +D G + N
Sbjct: 20002 LKIPIKGKPAPSVSWKKGEDPLATD-TRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 20059
Score = 28.9 bits (63), Expect = 8.4
Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 72 GQTAELHCKVSGNPPPTIRWF--KNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYF 129
GQ+ C+++G P + W+ N+ +Q+ +SF + + +I ++G +
Sbjct: 4876 GQSTTFECQITGTPKIRVSWYLDGNEITAIQK-HGISFIDGL--ATFQISGARVENSGTY 4932
Query: 130 QCVATNGKEVVSSTGVLFVKFGPPPT 155
C A N S + L VK PPT
Sbjct: 4933 VCEARNDAGTASCSIELKVK--EPPT 4956
Score = 28.9 bits (63), Expect = 8.4
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 12/96 (12%)
Query: 72 GQTAELHCKVSGNPPPTIRWFK-------NDAPVVQEP--RRLSFRSTIYGSRLRIRNLD 122
G + K+ G P PT+ WFK N PV+ + +L T L I
Sbjct: 16131 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDT---CTLVIPQSR 16187
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
+DTG + A N S L V P P P
Sbjct: 16188 RSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGP 16223
Score = 28.9 bits (63), Expect = 8.4
Identities = 15/74 (20%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
E + + G++ + V G P P + WFK D +++ + + + L +R+
Sbjct: 27963 EYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGSTSLFVRDA 28021
Query: 122 DTTDTGYFQCVATN 135
G + A N
Sbjct: 28022 TRDHRGVYTVEAKN 28035
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 59.7 bits (143), Expect = 4e-09
Identities = 33/90 (36%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
Query: 307 INKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNS----QYPHTHTFTALRFPELNGGHSYC 362
I + +C+ G YRG S + SG C WNS Q H + A L G H+YC
Sbjct: 280 IEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGL-GPHAYC 338
Query: 363 RNPGNQKEAPWCFTLDENFKS-DLCDIPAC 391
RNP N E PWC+ + ++ S + C + AC
Sbjct: 339 RNPDND-ERPWCYVVKDSALSWEYCRLEAC 367
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 58.5 bits (140), Expect = 1e-08
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Query: 52 LNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTI 111
+N + ++ + + + SLG T C V GNP P WF N P+ R L+
Sbjct: 306 VNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLT----- 360
Query: 112 YGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
G+ L+I + D G +QCVA NG + STG L ++
Sbjct: 361 AGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIE 398
Score = 32.3 bits (72), Expect = 0.76
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 9/61 (14%)
Query: 77 LHCKVSGNPPPTIRWFKNDAPVV--QEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVAT 134
L C VSG P P + W K+ + RRL S L ++D D+G + C+A
Sbjct: 241 LECVVSGVPAPQVYWLKDGQDIAPGSNWRRLY-------SHLATDSVDPADSGNYSCMAG 293
Query: 135 N 135
N
Sbjct: 294 N 294
Score = 30.0 bits (66), Expect = 3.8
Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 11/90 (12%)
Query: 47 NISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPT-IRWFKNDAPVVQEPRRL 105
++SS+L Y T EP++ + LG LHC S P T I W N + +
Sbjct: 22 SVSSDLAP--YFT-SEPLSAVQ-KLGGPVVLHC--SAQPVTTRISWLHNGKTLDGNLEHV 75
Query: 106 SFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
I+ L I +L+++ GY+QC+A N
Sbjct: 76 K----IHQGTLTILSLNSSLLGYYQCLANN 101
Score = 29.3 bits (64), Expect = 6.4
Identities = 11/34 (32%), Positives = 16/34 (47%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRL 105
G L C SG P P IRW+ + + P ++
Sbjct: 419 GDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQV 452
>gi|15147240 brother of CDO [Homo sapiens]
Length = 1114
Score = 57.8 bits (138), Expect = 2e-08
Identities = 32/91 (35%), Positives = 53/91 (58%), Gaps = 9/91 (9%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLD 122
++ + GQ+A+L C+V GNPPP++ W +N P++ R RLS R+ LR+ ++
Sbjct: 329 LSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRA------LRVLSMG 382
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPP 153
D G +QC+A N EV S+ V+ ++ P
Sbjct: 383 PEDEGVYQCMAEN--EVGSAHAVVQLRTSRP 411
Score = 39.3 bits (90), Expect = 0.006
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I + GQ+ L C SG PPP + W K+ + V ++ S L I D+
Sbjct: 240 IIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYN-----KTRFLLSNLLIDTTSEEDS 294
Query: 127 GYFQCVATNGKEVVSSTGVLF-VKFGPPP 154
G ++C+A NG + +L+ V+ PP
Sbjct: 295 GTYRCMADNGVGQPGAAVILYNVQVFEPP 323
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 56.6 bits (135), Expect = 4e-08
Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
Query: 16 LLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTA 75
LL A R A ET LS ++ +I ++L + + M ++TT LG+ A
Sbjct: 24190 LLEATEYEFRVFAENETGLSRPRR----TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAA 24245
Query: 76 ELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
+L C++ G P P I+W++ ++Q R+ S L + + D G + C+ATN
Sbjct: 24246 QLSCQIVGRPLPDIKWYRFGKELIQS-RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATN 24304
Query: 136 GKEVVSSTGVLFVKFGPPPTASPGY 160
V ++ L ++ P PGY
Sbjct: 24305 EVGEVETSSKLLLQ--ATPQFHPGY 24327
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 3/92 (3%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQE-PRRLSFRSTIYGSRLR 117
TL + N+T G++ L C +SG P PT+ W++ D + +++F+S I +RL
Sbjct: 898 TLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLM 955
Query: 118 IRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
IR D+G F C A N VS++ L V+
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 48 ISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPV-VQEPRRLS 106
+S EL+ D+ + +P + + GQ C++SG P P I WFKN+ P+ + +S
Sbjct: 26821 LSKELS-DAPAFISQPRSQ-NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSIS 26878
Query: 107 FRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFV 148
+Y L IRN +D+G + A N + S+T L V
Sbjct: 26879 RSRNVYS--LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 1/109 (0%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRI 118
+L P N + G+ ++ V G P P I W K+ P +++ R++ T + L I
Sbjct: 18008 SLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEP-LKQTTRVNVEETATSTVLHI 18066
Query: 119 RNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
+ + D G + ATN + + V P P P DE D
Sbjct: 18067 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSAD 18115
Score = 44.3 bits (103), Expect = 2e-04
Identities = 23/64 (35%), Positives = 33/64 (51%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
GQ+ +VSG PPPT++W K+ P+ P + L IR+ DTGY++
Sbjct: 25504 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25563
Query: 132 VATN 135
ATN
Sbjct: 25564 TATN 25567
Score = 42.7 bits (99), Expect = 6e-04
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+ +LG A+ C++ P +WFK + E + S RS+ Y S L I D
Sbjct: 4538 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDC 4596
Query: 127 GYFQCVATNGKEVVSSTGVLFV 148
G + C A+N VS T L V
Sbjct: 4597 GEYTCKASNEYGSVSCTATLTV 4618
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 2/144 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
GQ V P ++W+ N + QE ++ + +T L I + T D+G ++
Sbjct: 26083 GQNTRFILNVQSKPTAEVKWYHNGVEL-QESSKIHYTNTSGVLTLEILDCHTDDSGTYRA 26141
Query: 132 VATNGKEVVSSTGVLFVKFGPPPT-ASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYME 190
V TN K S L V G T AS +E F + R A A +T ME
Sbjct: 26142 VCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEME 26201
Query: 191 SLHMQGEIENQITAAFTMIGTSSH 214
+ E+++Q+T + + H
Sbjct: 26202 ASSSVREVKSQMTETRESLSSYEH 26225
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR----RLSFRSTIYGS 114
T +P+ ++ G TA +SG P P + WF+ D V+ ++SF +
Sbjct: 7 TFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR-DGQVISTSTLPGVQISFSDG--RA 63
Query: 115 RLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGY 160
+L I + ++G + ATNG +ST L VK TA P +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK---AETAPPNF 106
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 1/103 (0%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
N T G+ ++ G P P + W K++ P +++ R++ ST S L I++
Sbjct: 15850 NTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVP-LKQTTRVNAESTENNSLLTIKDACRE 15908
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
D G++ TN T + V P P P DE D
Sbjct: 15909 DVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTAD 15951
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 7/118 (5%)
Query: 32 TELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRW 91
TE +V+ + P + ISS+ + + + T S A+ K +G P PT W
Sbjct: 26527 TESTVTRKTEPKAPEPISSKP------VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIW 26580
Query: 92 FKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
K D + + + G L I DT+D+G + C N VSS+ L +K
Sbjct: 26581 TK-DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26637
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 1/101 (0%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+ G ++ V G P PT+ W K D ++++ +R++F +T + L I +D+
Sbjct: 14770 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATSTILNINECVRSDS 14828
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
G + A N V + V P P P DE D
Sbjct: 14829 GPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14869
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 8/127 (6%)
Query: 31 ETELSVSAE-LVPTSSWN-ISSELNKDSYLTLDEP-----MNNITTSLGQTAELHCKVSG 83
E E V E L S W+ IS + S + + P + N+ A L CKV+G
Sbjct: 24589 EYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTG 24648
Query: 84 NPPPTIRWFKNDAPVVQEPRRLSFRSTIYG-SRLRIRNLDTTDTGYFQCVATNGKEVVSS 142
+P P ++W++ ++ + + + G +L I ++ D +Q ATN VS
Sbjct: 24649 HPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSG 24708
Query: 143 TGVLFVK 149
T L V+
Sbjct: 24709 TASLEVE 24715
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 1/103 (0%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD 122
P I G+ EL ++G PPP WF + ++E R++ + ++L IR
Sbjct: 23439 PQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSK-LRESERVTVETHTKVAKLTIRETT 23497
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYE 165
DTG + N S T + + P P P DE +
Sbjct: 23498 IRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 23540
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I G + VSG PPPT+ W N+ + P+ + +T S + I+N +
Sbjct: 10227 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL---PQEATIETTAISSSMVIKNCQRS 10283
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
G + +A N T ++ V P P +P
Sbjct: 10284 HQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP 10317
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I G++ ++ + G P PTI+W K D + RL +ST + + L +++
Sbjct: 16246 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQE-LSNTARLEIKSTDFATSLSVKDAVRV 16304
Query: 125 DTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
D+G + A N G+ V+ + + GPP
Sbjct: 16305 DSGNYILKAKNVAGERSVTVNVKVLDRPGPP 16335
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
+G T L + G P P + W K D P + T GS+L IRN D G +
Sbjct: 10927 VGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVTPVGSKLEIRNAAHEDGGIYS 10983
Query: 131 CVATN--GKEVVSSTGVLFVKFGPP 153
N G + VS ++ K GPP
Sbjct: 10984 LTVENPAGSKTVSVKVLVLDKPGPP 11008
Score = 38.5 bits (88), Expect = 0.011
Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVV--QEPRRLSFRSTIYGSRLRIRN 120
P+ N T +G+ ++ +P P + W+K+ + ++ +F S +L I +
Sbjct: 25390 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 25449
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTAS 157
+ T D + VA N S L V PPPT S
Sbjct: 25450 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDS 25486
Score = 38.1 bits (87), Expect = 0.014
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 5/102 (4%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIR 119
D + N G HCK+SG P P I W+K+ + R ++ F S LRI
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS-LRIP 1306
Query: 120 NLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP---PTASP 158
+ D G + A+N K +G L+V+ P PT P
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1348
Score = 38.1 bits (87), Expect = 0.014
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 1/92 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT G+ + V G P PT +W K + VV L+ S L I+++ D+
Sbjct: 12603 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS-SHLAVHKADSSSILIIKDVTRKDS 12661
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
GY+ A N + + V P P P
Sbjct: 12662 GYYSLTAENSSGTDTQKIKVVVMDAPGPPQPP 12693
Score = 38.1 bits (87), Expect = 0.014
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I + G+T L V G P PTI W + D ++E R ++T + + L +++
Sbjct: 17328 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKE-IEESARCEIKNTDFKALLIVKDAIRI 17386
Query: 125 DTGYFQCVATN 135
D G + A+N
Sbjct: 17387 DGGQYILRASN 17397
Score = 38.1 bits (87), Expect = 0.014
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I G+T L + G P P + W K+ + + R+ +STI + L +++ TD
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + +N G + + T + + GPP
Sbjct: 18472 GQYILKLSNVGGTKSIPITVKVLDRPGPP 18500
Score = 38.1 bits (87), Expect = 0.014
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
++T G++A C G P PT+ W + V+ R +T Y S I ++ +D
Sbjct: 26264 SMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARHQVTTTKYKSTFEISSVQASD 26322
Query: 126 TGYFQCVATNGK 137
G + V N +
Sbjct: 26323 EGNYSVVVENSE 26334
Score = 37.7 bits (86), Expect = 0.018
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 28/183 (15%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRN 120
P+ + TS GQ A C+VSG + W+ D + +P R FR T + +L I
Sbjct: 3304 PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKI--KPSRF-FRMTQFEDTYQLEIAE 3359
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPG-------YSDEYEEDGFCQPY 173
D G + VA+N VSST L ++ S G S + F +
Sbjct: 3360 AYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEE 3419
Query: 174 RGIA---CARFIGN---------RTVYMESLHMQGEIENQ---ITAAFTMIGTSSHLSDK 218
I+ F G+ +V S+H +++ TA+ + I S+ LS +
Sbjct: 3420 SKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKE 3479
Query: 219 CSQ 221
C++
Sbjct: 3480 CAK 3482
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKN-DAPVVQEPRRLSFRSTIYGSRLRIRN 120
E + N+ G E+ + +GNP P I W KN D V + ++ T + L+I +
Sbjct: 1514 EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1573
Query: 121 LDTTDTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
+ D+ ++ A N G++ + V+F P
Sbjct: 1574 TVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608
Score = 37.4 bits (85), Expect = 0.024
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ + G+ L VSG PPPT+ W K D ++ +L + + + L ++
Sbjct: 15164 DTVILKAGEAFRLEADVSGRPPPTMEWSK-DGKELEGTAKLEIKIADFSTNLVNKDSTRR 15222
Query: 125 DTGYFQCVATN 135
D+G + ATN
Sbjct: 15223 DSGAYTLTATN 15233
Score = 37.4 bits (85), Expect = 0.024
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
++ + +GQ ++ +SG P PTI W K+ P +++ R++ ++ + L I+
Sbjct: 16932 SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLP-LKQTTRINVTDSLDLTTLSIKETHKD 16990
Query: 125 DTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
D G + N G++ S V K PP
Sbjct: 16991 DGGQYGITVANVVGQKTASIEIVTLDKPDPP 17021
Score = 37.4 bits (85), Expect = 0.024
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G + +L +SG P PTI W+K+D +Q + +T + + I++ D ++G ++
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKE-LQTNALVCVENTTDLASILIKDADRLNSGCYEL 20640
Query: 132 VATNGKEVVSSTGVLFVKFGPPPTASP 158
N S+T + + P P P
Sbjct: 20641 KLRNAMGSASATIRVQILDKPGPPGGP 20667
Score = 37.0 bits (84), Expect = 0.031
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 9/132 (6%)
Query: 27 AAAQETELSVSAELVPTS-SWNISSELNKDSYLTLDEP-----MNNITTSLGQTAELHCK 80
A+ Q+T+L +A L + S +S E K+S T + P + ++T G TA+ C
Sbjct: 3454 ASVQDTQLCHTASLSQIAESTELSKECAKES--TGEAPKIFLHLQDVTVKCGDTAQFLCV 3511
Query: 81 VSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVV 140
+ + + W A + +E RL L I N+ D G + C+ N
Sbjct: 3512 LKDDSFIDVTWTHEGAKI-EESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGER 3570
Query: 141 SSTGVLFVKFGP 152
+++ VL V+ P
Sbjct: 3571 TTSAVLSVEGAP 3582
Score = 37.0 bits (84), Expect = 0.031
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT +GQT + +V G P P I W K +V+E +R+ + L+I+ D
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE-KRVDLIQDLPRVELQIKEAVRADH 11671
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPP 154
G + A N + ++ V P P
Sbjct: 11672 GKYIISAKNSSGHAQGSAIVNVLDRPGP 11699
Score = 36.6 bits (83), Expect = 0.040
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ +T +G+ L + SG P P + WFK++A V+++ R ++T L +
Sbjct: 10521 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDD-RTHIKTTPATLALEKIKAKRS 10579
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
D+G + V N + V P P P DE +D
Sbjct: 10580 DSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 51 ELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRS 109
E K + EP+ + G+TA C+V+G P P + W+ N + + R R+ +
Sbjct: 1791 EKQKPDIVLYPEPVRVLE---GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847
Query: 110 TIYGSRLRIRNLDTTDTGYFQCVATNGKEVV 140
Y L I + + DTG + A N + V+
Sbjct: 1848 IHY---LDIVDCKSYDTGEVKVTAENPEGVI 1875
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+T G EL V+G P P I W K D ++++ +R++ + S + I + +DT
Sbjct: 7395 LTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVPKKSTVTIVDSKRSDT 7453
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + A N G+ + K GPP
Sbjct: 7454 GTYIIEAVNVCGRATAVVEVNVLDKPGPP 7482
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G T L+ V G PPP I W K + +++ L +ST + + LR N++ D G +
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVN-LRDRIGLDIKSTDFDTFLRCENVNKYDAGKYIL 13461
Query: 132 VATN--GKEVVSSTGVLFVKFGPP 153
N GK+ + + GPP
Sbjct: 13462 TLENSCGKKEYTIVVKVLDTPGPP 13485
Score = 35.8 bits (81), Expect = 0.069
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
D P +T +G L G P P+I W K+ P ++E + F T L I+N
Sbjct: 21262 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLP-LKESEFVRFSKTENKITLSIKN 21320
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP 153
G + + N + + + + GPP
Sbjct: 21321 AKKEHGGKYTVILDNAVCRI-AVPITVITLGPP 21352
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I G+ +++ ++G P P I W K D ++E R ST + L +++ DT
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDT 19552
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + N G V+ + K GPP
Sbjct: 19553 GQYVLTLKNVAGTRSVAVNCKVLDKPGPP 19581
Score = 35.0 bits (79), Expect = 0.12
Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
++ G+ ++ G PPPT+ W K++ + + R S +T S L I + D
Sbjct: 20975 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 21033
Query: 126 TGYFQCVATNG 136
TG + NG
Sbjct: 21034 TGKYILTIENG 21044
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
D+ +T G + L VSG PPP I W K + R +T S L +
Sbjct: 23145 DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS---RAIIDTTESYSLLIVDK 23201
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTAS 157
++ D G + A N S+T ++ V P P S
Sbjct: 23202 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS 23238
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 3/140 (2%)
Query: 28 AAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNI-TTSLGQTAELHCKVSGNPP 86
A T +++S P+ I +E N + L M ++ T G L V G P
Sbjct: 12961 AIARTAVNISPPSEPSDPVTILAE-NVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 13019
Query: 87 PTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVL 146
PT+ W K D +++ + L + +++ D+G + A N S+T L
Sbjct: 13020 PTVSW-KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKL 13078
Query: 147 FVKFGPPPTASPGYSDEYEE 166
V P P AS + Y +
Sbjct: 13079 KVLDKPGPPASVKINKMYSD 13098
Score = 34.3 bits (77), Expect = 0.20
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 29 AQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPT 88
AQ ELS +A+L L D Y T+ +++ T L C+VS + P
Sbjct: 5340 AQVKELSSTAQL---------KVLEADPYFTVK--LHDKTAVEKDEITLKCEVSKDVP-- 5386
Query: 89 IRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
++WFK+ +V P + S ++ L+I+ D D G + C
Sbjct: 5387 VKWFKDGEEIVPSP-KYSIKADGLRRILKIKKADLKDKGEYVC 5428
Score = 34.3 bits (77), Expect = 0.20
Identities = 46/216 (21%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 54 KDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYG 113
K + L P+ ++T + G+TA C++S P + W+ ++ ++ RS
Sbjct: 5887 KPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLK-GKKLEPSDKVVPRSEGKV 5944
Query: 114 SRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGF---- 169
L +R++ D G Q A + K + LFVK PP + D+ E+G
Sbjct: 5945 HTLTLRDVKLEDAGEVQLTAKDFKTHAN----LFVK-EPPVEFTKPLEDQTVEEGATAVL 5999
Query: 170 -CQPYRGIACARFIGNRTVYMES----LHMQGEIENQITAAFTMIGTSSHLSD------K 218
C+ R A ++ N T ++S + G + + T ++ D
Sbjct: 6000 ECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTS 6059
Query: 219 CSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEI 254
C+ +P + P T + +++ R ECE+
Sbjct: 6060 CNLNVVPPHVEFLRPL---TDLQVREKEMARFECEL 6092
Score = 33.5 bits (75), Expect = 0.34
Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKN-DAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
+T G T L V G P P + W K+ DA + R+ + S+ + +D
Sbjct: 11906 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSD 11965
Query: 126 TGYFQCVATN--GKEVVSSTGVLFVKFGP 152
G + ATN G V +T + K GP
Sbjct: 11966 GGKYVVTATNTAGSFVAYATVNVLDKPGP 11994
Score = 33.1 bits (74), Expect = 0.45
Identities = 30/126 (23%), Positives = 50/126 (39%), Gaps = 20/126 (15%)
Query: 26 GAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNP 85
G A EL V AE P + + + ++T G L +V+G P
Sbjct: 87 GQATSTAELLVKAETAPPN---------------FVQRLQSMTVRQGSQVRLQVRVTGIP 131
Query: 86 PPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRNLDTTDTGYFQCVATNGKEVVSST 143
P ++++++ A + L F+ + G L I D+G + ATN +ST
Sbjct: 132 TPVVKFYRDGAEIQSS---LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATST 188
Query: 144 GVLFVK 149
L V+
Sbjct: 189 AELLVQ 194
Score = 33.1 bits (74), Expect = 0.45
Identities = 33/143 (23%), Positives = 53/143 (37%), Gaps = 5/143 (3%)
Query: 7 RGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNN 66
R T+ LL L + A A+E ++++ + S E K + E + +
Sbjct: 1986 RKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPK-----IFERIQS 2040
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
T G A +V G P P W+KN + + R + L IR++ D+
Sbjct: 2041 QTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDS 2100
Query: 127 GYFQCVATNGKEVVSSTGVLFVK 149
A N SS L V+
Sbjct: 2101 ASIMVKAINIAGETSSHAFLLVQ 2123
Score = 33.1 bits (74), Expect = 0.45
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+ + G T + G P PT +W D ++ + + + S L I+N
Sbjct: 11212 IEGLVVKAGTTVRFPAIIRGVPVPTAKW-TTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11270
Query: 124 TDTGYFQCVATN---GKEVVSSTGVLFVKFGPP 153
DTG +Q +N K V VL V GPP
Sbjct: 11271 RDTGEYQITVSNAAGSKTVAVHLTVLDVP-GPP 11302
Score = 33.1 bits (74), Expect = 0.45
Identities = 21/97 (21%), Positives = 42/97 (43%), Gaps = 3/97 (3%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRI 118
+++ P + + ++ G P T+ W K D ++E R++ S+ + L I
Sbjct: 19091 SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRK-DGQTLKETTRVNVSSSKTVTSLSI 19149
Query: 119 RNLDTTDTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
+ D G ++ +N G V T ++ + GPP
Sbjct: 19150 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP 19186
Score = 32.7 bits (73), Expect = 0.58
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 32/144 (22%)
Query: 60 LDEPMNNITTSL----GQTAELHCKVSGNPPPTIRWFKND------------APVV---- 99
+D P + TSL G L +SG+P PTI W K++ AP+V
Sbjct: 8373 IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRK 8432
Query: 100 -----QEP------RRLSFRSTIYG-SRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLF 147
+EP +RLS ++ G S+LR+R+ D G + N + + +
Sbjct: 8433 GEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVS 8492
Query: 148 VKFGPPPTASPGYSDEYEEDGFCQ 171
V P P + + D + C+
Sbjct: 8493 VLDTPGPPINFVFEDIRKTSVLCK 8516
Score = 31.2 bits (69), Expect = 1.7
Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
G + C+V GNP P + W K+ P+ R ++S+ +L I D G +
Sbjct: 1050 GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYT 1109
Query: 131 CVATNGKEVVSSTGVL 146
V N S++ L
Sbjct: 1110 IVVRNKHGETSASASL 1125
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRN 120
P+ ++ G A L CKVS +++W+ ND + + R ++ + G+ RL I
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR---VQAIVKGTKQRLVINR 2460
Query: 121 LDTTDTGYFQCV 132
+D G ++ +
Sbjct: 2461 THASDEGPYKLI 2472
Score = 31.2 bits (69), Expect = 1.7
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVV-QEPRRLSFRSTIYGSRLRIRNLD 122
++N S+G A L V G P P I+WF N + + F + + L+
Sbjct: 3655 VSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLE 3714
Query: 123 TTDTGYFQCVATN--GKEVVSS 142
D G + C+A+N GK + S+
Sbjct: 3715 --DEGEYTCMASNDYGKTICSA 3734
Score = 31.2 bits (69), Expect = 1.7
Identities = 26/119 (21%), Positives = 43/119 (36%), Gaps = 8/119 (6%)
Query: 51 ELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRST 110
EL+ DS L I G +A +H G P P I W + + ++
Sbjct: 17718 ELDLDSELR-----KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD---KVQIEKG 17769
Query: 111 IYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGF 169
+ ++L I N D D G + N S+ + V P P + + ++ F
Sbjct: 17770 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAF 17828
Score = 30.8 bits (68), Expect = 2.2
Identities = 23/105 (21%), Positives = 41/105 (39%), Gaps = 2/105 (1%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD 122
P + + G ++ +SG P P + ++ P ++ R + T + ++
Sbjct: 20177 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVP-LKATMRFNTEITAENLTINLKESV 20235
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGP-PPTASPGYSDEYEE 166
T D G ++ A N + + V P PPT SD EE
Sbjct: 20236 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEE 20280
Score = 30.4 bits (67), Expect = 2.9
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT G + +SG P P + W K + ++E R+S +T + L +++ D+
Sbjct: 22352 ITCKAGSPFTIDVPISGRPAPKVTW-KLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDS 22410
Query: 127 G-YFQCVA-TNGKEVVSSTGVLFVKFGP 152
G YF + T G + S T V+ + GP
Sbjct: 22411 GRYFLTLENTAGVKTFSVTVVVIGRPGP 22438
Score = 30.0 bits (66), Expect = 3.8
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
+G +A C VS + T W K+ + + + P+ F + +L I ++ +D G +
Sbjct: 4827 VGSSAIFECLVSPSTAITT-WMKDGSNIRESPKH-RFIADGKDRKLHIIDVQLSDAGEYT 4884
Query: 131 CVATNGKEVVSSTGVLFVK 149
CV G + +ST L V+
Sbjct: 4885 CVLRLGNKEKTSTAKLVVE 4903
Score = 29.6 bits (65), Expect = 4.9
Identities = 22/97 (22%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
+ + +T G+ A +SG P P I W+K + ++ + F L +
Sbjct: 3197 QELQPVTVQSGKPARFCAVISGRPQPKISWYKEE-QLLSTGFKCKFLHDGQEYTLLLIEA 3255
Query: 122 DTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
D + C A N V +++ L V+ P SP
Sbjct: 3256 FPEDAAVYTCEAKNDYGVATTSASLSVEV--PEVVSP 3290
Score = 29.6 bits (65), Expect = 4.9
Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G + L G P PT W K D+ + R +T S L + N + D G +
Sbjct: 22067 GASIRLFIAYQGRPTPTAVWSKPDSNL---SLRADIHTTDSFSTLTVENCNRNDAGKYTL 22123
Query: 132 VATN--GKEVVSSTGVLFVKFGPP 153
N G + ++ T + GPP
Sbjct: 22124 TVENNSGSKSITFTVKVLDTPGPP 22147
Score = 29.6 bits (65), Expect = 4.9
Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 70 SLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD-TTDTGY 128
++G T LH G P P + WF + ++Q ++ +T + + L ++N+ T G
Sbjct: 24336 AVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK 24394
Query: 129 FQCVATN 135
++ +N
Sbjct: 24395 YKVQLSN 24401
Score = 29.3 bits (64), Expect = 6.4
Identities = 14/59 (23%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 77 LHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
L + G P P++ W K + P+ + R+S S+ + L + + +D G + N
Sbjct: 13697 LKIPIKGKPAPSVSWKKGEDPLATD-TRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13754
Score = 28.9 bits (63), Expect = 8.4
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 12/96 (12%)
Query: 72 GQTAELHCKVSGNPPPTIRWFK-------NDAPVVQEP--RRLSFRSTIYGSRLRIRNLD 122
G + K+ G P PT+ WFK N PV+ + +L T L I
Sbjct: 9826 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDT---CTLVIPQSR 9882
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
+DTG + A N S L V P P P
Sbjct: 9883 RSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGP 9918
Score = 28.9 bits (63), Expect = 8.4
Identities = 15/74 (20%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
E + + G++ + V G P P + WFK D +++ + + + L +R+
Sbjct: 21658 EYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGSTSLFVRDA 21716
Query: 122 DTTDTGYFQCVATN 135
G + A N
Sbjct: 21717 TRDHRGVYTVEAKN 21730
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 56.6 bits (135), Expect = 4e-08
Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
Query: 16 LLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTA 75
LL A R A ET LS ++ +I ++L + + M ++TT LG+ A
Sbjct: 24123 LLEATEYEFRVFAENETGLSRPRR----TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAA 24178
Query: 76 ELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
+L C++ G P P I+W++ ++Q R+ S L + + D G + C+ATN
Sbjct: 24179 QLSCQIVGRPLPDIKWYRFGKELIQS-RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATN 24237
Query: 136 GKEVVSSTGVLFVKFGPPPTASPGY 160
V ++ L ++ P PGY
Sbjct: 24238 EVGEVETSSKLLLQ--ATPQFHPGY 24260
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 3/92 (3%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQE-PRRLSFRSTIYGSRLR 117
TL + N+T G++ L C +SG P PT+ W++ D + +++F+S I +RL
Sbjct: 898 TLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLM 955
Query: 118 IRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
IR D+G F C A N VS++ L V+
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 48 ISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPV-VQEPRRLS 106
+S EL+ D+ + +P + + GQ C++SG P P I WFKN+ P+ + +S
Sbjct: 26754 LSKELS-DAPAFISQPRSQ-NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSIS 26811
Query: 107 FRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFV 148
+Y L IRN +D+G + A N + S+T L V
Sbjct: 26812 RSRNVYS--LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 1/109 (0%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRI 118
+L P N + G+ ++ V G P P I W K+ P +++ R++ T + L I
Sbjct: 17941 SLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEP-LKQTTRVNVEETATSTVLHI 17999
Query: 119 RNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
+ + D G + ATN + + V P P P DE D
Sbjct: 18000 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSAD 18048
Score = 44.3 bits (103), Expect = 2e-04
Identities = 23/64 (35%), Positives = 33/64 (51%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
GQ+ +VSG PPPT++W K+ P+ P + L IR+ DTGY++
Sbjct: 25437 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25496
Query: 132 VATN 135
ATN
Sbjct: 25497 TATN 25500
Score = 42.7 bits (99), Expect = 6e-04
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+ +LG A+ C++ P +WFK + E + S RS+ Y S L I D
Sbjct: 4471 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDC 4529
Query: 127 GYFQCVATNGKEVVSSTGVLFV 148
G + C A+N VS T L V
Sbjct: 4530 GEYTCKASNEYGSVSCTATLTV 4551
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 2/144 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
GQ V P ++W+ N + QE ++ + +T L I + T D+G ++
Sbjct: 26016 GQNTRFILNVQSKPTAEVKWYHNGVEL-QESSKIHYTNTSGVLTLEILDCHTDDSGTYRA 26074
Query: 132 VATNGKEVVSSTGVLFVKFGPPPT-ASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYME 190
V TN K S L V G T AS +E F + R A A +T ME
Sbjct: 26075 VCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEME 26134
Query: 191 SLHMQGEIENQITAAFTMIGTSSH 214
+ E+++Q+T + + H
Sbjct: 26135 ASSSVREVKSQMTETRESLSSYEH 26158
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR----RLSFRSTIYGS 114
T +P+ ++ G TA +SG P P + WF+ D V+ ++SF +
Sbjct: 7 TFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR-DGQVISTSTLPGVQISFSDG--RA 63
Query: 115 RLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGY 160
+L I + ++G + ATNG +ST L VK TA P +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK---AETAPPNF 106
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 1/103 (0%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
N T G+ ++ G P P + W K++ P +++ R++ ST S L I++
Sbjct: 15783 NTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVP-LKQTTRVNAESTENNSLLTIKDACRE 15841
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
D G++ TN T + V P P P DE D
Sbjct: 15842 DVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTAD 15884
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 7/118 (5%)
Query: 32 TELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRW 91
TE +V+ + P + ISS+ + + + T S A+ K +G P PT W
Sbjct: 26460 TESTVTRKTEPKAPEPISSKP------VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIW 26513
Query: 92 FKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVK 149
K D + + + G L I DT+D+G + C N VSS+ L +K
Sbjct: 26514 TK-DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26570
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 1/101 (0%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+ G ++ V G P PT+ W K D ++++ +R++F +T + L I +D+
Sbjct: 14703 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATSTILNINECVRSDS 14761
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
G + A N V + V P P P DE D
Sbjct: 14762 GPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14802
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 8/127 (6%)
Query: 31 ETELSVSAE-LVPTSSWN-ISSELNKDSYLTLDEP-----MNNITTSLGQTAELHCKVSG 83
E E V E L S W+ IS + S + + P + N+ A L CKV+G
Sbjct: 24522 EYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTG 24581
Query: 84 NPPPTIRWFKNDAPVVQEPRRLSFRSTIYG-SRLRIRNLDTTDTGYFQCVATNGKEVVSS 142
+P P ++W++ ++ + + + G +L I ++ D +Q ATN VS
Sbjct: 24582 HPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSG 24641
Query: 143 TGVLFVK 149
T L V+
Sbjct: 24642 TASLEVE 24648
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 1/103 (0%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD 122
P I G+ EL ++G PPP WF + ++E R++ + ++L IR
Sbjct: 23372 PQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSK-LRESERVTVETHTKVAKLTIRETT 23430
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYE 165
DTG + N S T + + P P P DE +
Sbjct: 23431 IRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 23473
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I G + VSG PPPT+ W N+ + P+ + +T S + I+N +
Sbjct: 10160 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL---PQEATIETTAISSSMVIKNCQRS 10216
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
G + +A N T ++ V P P +P
Sbjct: 10217 HQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP 10250
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I G++ ++ + G P PTI+W K D + RL +ST + + L +++
Sbjct: 16179 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQE-LSNTARLEIKSTDFATSLSVKDAVRV 16237
Query: 125 DTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
D+G + A N G+ V+ + + GPP
Sbjct: 16238 DSGNYILKAKNVAGERSVTVNVKVLDRPGPP 16268
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
+G T L + G P P + W K D P + T GS+L IRN D G +
Sbjct: 10860 VGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVTPVGSKLEIRNAAHEDGGIYS 10916
Query: 131 CVATN--GKEVVSSTGVLFVKFGPP 153
N G + VS ++ K GPP
Sbjct: 10917 LTVENPAGSKTVSVKVLVLDKPGPP 10941
Score = 38.9 bits (89), Expect = 0.008
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 12/119 (10%)
Query: 39 ELVPTSSWNISSELN--------KDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIR 90
E S W++S ++ K S++ +P++++ G+T H +VSG P P I+
Sbjct: 3395 ENTSNSQWHVSLSVSFKKEPLGQKPSFI---QPLSSLRVHNGETVRFHARVSGIPKPEIQ 3451
Query: 91 WFKNDAPVV-QEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFV 148
WF N ++ + F + + + I + + G + C A N + L V
Sbjct: 3452 WFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 38.5 bits (88), Expect = 0.011
Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVV--QEPRRLSFRSTIYGSRLRIRN 120
P+ N T +G+ ++ +P P + W+K+ + ++ +F S +L I +
Sbjct: 25323 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 25382
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTAS 157
+ T D + VA N S L V PPPT S
Sbjct: 25383 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDS 25419
Score = 38.1 bits (87), Expect = 0.014
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 5/102 (4%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIR 119
D + N G HCK+SG P P I W+K+ + R ++ F S LRI
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS-LRIP 1306
Query: 120 NLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP---PTASP 158
+ D G + A+N K +G L+V+ P PT P
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1348
Score = 38.1 bits (87), Expect = 0.014
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 1/92 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT G+ + V G P PT +W K + VV L+ S L I+++ D+
Sbjct: 12536 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS-SHLAVHKADSSSILIIKDVTRKDS 12594
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
GY+ A N + + V P P P
Sbjct: 12595 GYYSLTAENSSGTDTQKIKVVVMDAPGPPQPP 12626
Score = 38.1 bits (87), Expect = 0.014
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ I + G+T L V G P PTI W + D ++E R ++T + + L +++
Sbjct: 17261 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKE-IEESARCEIKNTDFKALLIVKDAIRI 17319
Query: 125 DTGYFQCVATN 135
D G + A+N
Sbjct: 17320 DGGQYILRASN 17330
Score = 38.1 bits (87), Expect = 0.014
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I G+T L + G P P + W K+ + + R+ +STI + L +++ TD
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + +N G + + T + + GPP
Sbjct: 18405 GQYILKLSNVGGTKSIPITVKVLDRPGPP 18433
Score = 38.1 bits (87), Expect = 0.014
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
++T G++A C G P PT+ W + V+ R +T Y S I ++ +D
Sbjct: 26197 SMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARHQVTTTKYKSTFEISSVQASD 26255
Query: 126 TGYFQCVATNGK 137
G + V N +
Sbjct: 26256 EGNYSVVVENSE 26267
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKN-DAPVVQEPRRLSFRSTIYGSRLRIRN 120
E + N+ G E+ + +GNP P I W KN D V + ++ T + L+I +
Sbjct: 1514 EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1573
Query: 121 LDTTDTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
+ D+ ++ A N G++ + V+F P
Sbjct: 1574 TVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608
Score = 37.4 bits (85), Expect = 0.024
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 6/86 (6%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRN 120
P+ + TS GQ A C+VSG + W+ D + +P R FR T + +L I
Sbjct: 3304 PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKI--KPSRF-FRMTQFEDTYQLEIAE 3359
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVL 146
D G + VA+N VSST L
Sbjct: 3360 AYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 37.4 bits (85), Expect = 0.024
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ + G+ L VSG PPPT+ W K D ++ +L + + + L ++
Sbjct: 15097 DTVILKAGEAFRLEADVSGRPPPTMEWSK-DGKELEGTAKLEIKIADFSTNLVNKDSTRR 15155
Query: 125 DTGYFQCVATN 135
D+G + ATN
Sbjct: 15156 DSGAYTLTATN 15166
Score = 37.4 bits (85), Expect = 0.024
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
++ + +GQ ++ +SG P PTI W K+ P +++ R++ ++ + L I+
Sbjct: 16865 SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLP-LKQTTRINVTDSLDLTTLSIKETHKD 16923
Query: 125 DTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
D G + N G++ S V K PP
Sbjct: 16924 DGGQYGITVANVVGQKTASIEIVTLDKPDPP 16954
Score = 37.4 bits (85), Expect = 0.024
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G + +L +SG P PTI W+K+D +Q + +T + + I++ D ++G ++
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKE-LQTNALVCVENTTDLASILIKDADRLNSGCYEL 20573
Query: 132 VATNGKEVVSSTGVLFVKFGPPPTASP 158
N S+T + + P P P
Sbjct: 20574 KLRNAMGSASATIRVQILDKPGPPGGP 20600
Score = 37.0 bits (84), Expect = 0.031
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT +GQT + +V G P P I W K +V+E +R+ + L+I+ D
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE-KRVDLIQDLPRVELQIKEAVRADH 11604
Query: 127 GYFQCVATNGKEVVSSTGVLFVKFGPPP 154
G + A N + ++ V P P
Sbjct: 11605 GKYIISAKNSSGHAQGSAIVNVLDRPGP 11632
Score = 36.6 bits (83), Expect = 0.040
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 65 NNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTT 124
+ +T +G+ L + SG P P + WFK++A V+++ R ++T L +
Sbjct: 10454 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDD-RTHIKTTPATLALEKIKAKRS 10512
Query: 125 DTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEED 167
D+G + V N + V P P P DE +D
Sbjct: 10513 DSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 51 ELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRS 109
E K + EP+ + G+TA C+V+G P P + W+ N + + R R+ +
Sbjct: 1791 EKQKPDIVLYPEPVRVLE---GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847
Query: 110 TIYGSRLRIRNLDTTDTGYFQCVATNGKEVV 140
Y L I + + DTG + A N + V+
Sbjct: 1848 IHY---LDIVDCKSYDTGEVKVTAENPEGVI 1875
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
+T G EL V+G P P I W K D ++++ +R++ + S + I + +DT
Sbjct: 7328 LTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVPKKSTVTIVDSKRSDT 7386
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + A N G+ + K GPP
Sbjct: 7387 GTYIIEAVNVCGRATAVVEVNVLDKPGPP 7415
Score = 36.2 bits (82), Expect = 0.053
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G T L+ V G PPP I W K + +++ L +ST + + LR N++ D G +
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVN-LRDRIGLDIKSTDFDTFLRCENVNKYDAGKYIL 13394
Query: 132 VATN--GKEVVSSTGVLFVKFGPP 153
N GK+ + + GPP
Sbjct: 13395 TLENSCGKKEYTIVVKVLDTPGPP 13418
Score = 35.8 bits (81), Expect = 0.069
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
D P +T +G L G P P+I W K+ P ++E + F T L I+N
Sbjct: 21195 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLP-LKESEFVRFSKTENKITLSIKN 21253
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP 153
G + + N + + + + GPP
Sbjct: 21254 AKKEHGGKYTVILDNAVCRI-AVPITVITLGPP 21285
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
I G+ +++ ++G P P I W K D ++E R ST + L +++ DT
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDT 19485
Query: 127 GYFQCVATN--GKEVVSSTGVLFVKFGPP 153
G + N G V+ + K GPP
Sbjct: 19486 GQYVLTLKNVAGTRSVAVNCKVLDKPGPP 19514
Score = 35.0 bits (79), Expect = 0.12
Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 66 NITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
++ G+ ++ G PPPT+ W K++ + + R S +T S L I + D
Sbjct: 20908 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20966
Query: 126 TGYFQCVATNG 136
TG + NG
Sbjct: 20967 TGKYILTIENG 20977
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Query: 61 DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN 120
D+ +T G + L VSG PPP I W K + R +T S L +
Sbjct: 23078 DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS---RAIIDTTESYSLLIVDK 23134
Query: 121 LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTAS 157
++ D G + A N S+T ++ V P P S
Sbjct: 23135 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS 23171
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 3/140 (2%)
Query: 28 AAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNI-TTSLGQTAELHCKVSGNPP 86
A T +++S P+ I +E N + L M ++ T G L V G P
Sbjct: 12894 AIARTAVNISPPSEPSDPVTILAE-NVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 12952
Query: 87 PTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVL 146
PT+ W K D +++ + L + +++ D+G + A N S+T L
Sbjct: 12953 PTVSW-KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKL 13011
Query: 147 FVKFGPPPTASPGYSDEYEE 166
V P P AS + Y +
Sbjct: 13012 KVLDKPGPPASVKINKMYSD 13031
Score = 34.3 bits (77), Expect = 0.20
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 29 AQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPT 88
AQ ELS +A+L L D Y T+ +++ T L C+VS + P
Sbjct: 5273 AQVKELSSTAQL---------KVLEADPYFTVK--LHDKTAVEKDEITLKCEVSKDVP-- 5319
Query: 89 IRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
++WFK+ +V P + S ++ L+I+ D D G + C
Sbjct: 5320 VKWFKDGEEIVPSP-KYSIKADGLRRILKIKKADLKDKGEYVC 5361
Score = 34.3 bits (77), Expect = 0.20
Identities = 46/216 (21%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 54 KDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYG 113
K + L P+ ++T + G+TA C++S P + W+ ++ ++ RS
Sbjct: 5820 KPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLK-GKKLEPSDKVVPRSEGKV 5877
Query: 114 SRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGF---- 169
L +R++ D G Q A + K + LFVK PP + D+ E+G
Sbjct: 5878 HTLTLRDVKLEDAGEVQLTAKDFKTHAN----LFVK-EPPVEFTKPLEDQTVEEGATAVL 5932
Query: 170 -CQPYRGIACARFIGNRTVYMES----LHMQGEIENQITAAFTMIGTSSHLSD------K 218
C+ R A ++ N T ++S + G + + T ++ D
Sbjct: 5933 ECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTS 5992
Query: 219 CSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEI 254
C+ +P + P T + +++ R ECE+
Sbjct: 5993 CNLNVVPPHVEFLRPL---TDLQVREKEMARFECEL 6025
Score = 33.5 bits (75), Expect = 0.34
Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKN-DAPVVQEPRRLSFRSTIYGSRLRIRNLDTTD 125
+T G T L V G P P + W K+ DA + R+ + S+ + +D
Sbjct: 11839 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSD 11898
Query: 126 TGYFQCVATN--GKEVVSSTGVLFVKFGP 152
G + ATN G V +T + K GP
Sbjct: 11899 GGKYVVTATNTAGSFVAYATVNVLDKPGP 11927
Score = 33.1 bits (74), Expect = 0.45
Identities = 30/126 (23%), Positives = 50/126 (39%), Gaps = 20/126 (15%)
Query: 26 GAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNP 85
G A EL V AE P + + + ++T G L +V+G P
Sbjct: 87 GQATSTAELLVKAETAPPN---------------FVQRLQSMTVRQGSQVRLQVRVTGIP 131
Query: 86 PPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRNLDTTDTGYFQCVATNGKEVVSST 143
P ++++++ A + L F+ + G L I D+G + ATN +ST
Sbjct: 132 TPVVKFYRDGAEIQSS---LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATST 188
Query: 144 GVLFVK 149
L V+
Sbjct: 189 AELLVQ 194
Score = 33.1 bits (74), Expect = 0.45
Identities = 33/143 (23%), Positives = 53/143 (37%), Gaps = 5/143 (3%)
Query: 7 RGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNN 66
R T+ LL L + A A+E ++++ + S E K + E + +
Sbjct: 1986 RKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPK-----IFERIQS 2040
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
T G A +V G P P W+KN + + R + L IR++ D+
Sbjct: 2041 QTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDS 2100
Query: 127 GYFQCVATNGKEVVSSTGVLFVK 149
A N SS L V+
Sbjct: 2101 ASIMVKAINIAGETSSHAFLLVQ 2123
Score = 33.1 bits (74), Expect = 0.45
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT 123
+ + G T + G P PT +W D ++ + + + S L I+N
Sbjct: 11145 IEGLVVKAGTTVRFPAIIRGVPVPTAKW-TTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11203
Query: 124 TDTGYFQCVATN---GKEVVSSTGVLFVKFGPP 153
DTG +Q +N K V VL V GPP
Sbjct: 11204 RDTGEYQITVSNAAGSKTVAVHLTVLDVP-GPP 11235
Score = 33.1 bits (74), Expect = 0.45
Identities = 21/97 (21%), Positives = 42/97 (43%), Gaps = 3/97 (3%)
Query: 59 TLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRI 118
+++ P + + ++ G P T+ W K D ++E R++ S+ + L I
Sbjct: 19024 SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRK-DGQTLKETTRVNVSSSKTVTSLSI 19082
Query: 119 RNLDTTDTGYFQCVATN--GKEVVSSTGVLFVKFGPP 153
+ D G ++ +N G V T ++ + GPP
Sbjct: 19083 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP 19119
Score = 32.7 bits (73), Expect = 0.58
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 32/144 (22%)
Query: 60 LDEPMNNITTSL----GQTAELHCKVSGNPPPTIRWFKND------------APVV---- 99
+D P + TSL G L +SG+P PTI W K++ AP+V
Sbjct: 8306 IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRK 8365
Query: 100 -----QEP------RRLSFRSTIYG-SRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLF 147
+EP +RLS ++ G S+LR+R+ D G + N + + +
Sbjct: 8366 GEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVS 8425
Query: 148 VKFGPPPTASPGYSDEYEEDGFCQ 171
V P P + + D + C+
Sbjct: 8426 VLDTPGPPINFVFEDIRKTSVLCK 8449
Score = 31.2 bits (69), Expect = 1.7
Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPR-RLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
G + C+V GNP P + W K+ P+ R ++S+ +L I D G +
Sbjct: 1050 GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYT 1109
Query: 131 CVATNGKEVVSSTGVL 146
V N S++ L
Sbjct: 1110 IVVRNKHGETSASASL 1125
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGS--RLRIRN 120
P+ ++ G A L CKVS +++W+ ND + + R ++ + G+ RL I
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR---VQAIVKGTKQRLVINR 2460
Query: 121 LDTTDTGYFQCV 132
+D G ++ +
Sbjct: 2461 THASDEGPYKLI 2472
Score = 31.2 bits (69), Expect = 1.7
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
Query: 64 MNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVV-QEPRRLSFRSTIYGSRLRIRNLD 122
++N S+G A L V G P P I+WF N + + F + + L+
Sbjct: 3588 VSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLE 3647
Query: 123 TTDTGYFQCVATN--GKEVVSS 142
D G + C+A+N GK + S+
Sbjct: 3648 --DEGEYTCMASNDYGKTICSA 3667
Score = 31.2 bits (69), Expect = 1.7
Identities = 26/119 (21%), Positives = 43/119 (36%), Gaps = 8/119 (6%)
Query: 51 ELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRST 110
EL+ DS L I G +A +H G P P I W + + ++
Sbjct: 17651 ELDLDSELR-----KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD---KVQIEKG 17702
Query: 111 IYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGF 169
+ ++L I N D D G + N S+ + V P P + + ++ F
Sbjct: 17703 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAF 17761
Score = 30.8 bits (68), Expect = 2.2
Identities = 23/105 (21%), Positives = 41/105 (39%), Gaps = 2/105 (1%)
Query: 63 PMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD 122
P + + G ++ +SG P P + ++ P ++ R + T + ++
Sbjct: 20110 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVP-LKATMRFNTEITAENLTINLKESV 20168
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGP-PPTASPGYSDEYEE 166
T D G ++ A N + + V P PPT SD EE
Sbjct: 20169 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEE 20213
Score = 30.4 bits (67), Expect = 2.9
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 67 ITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDT 126
IT G + +SG P P + W K + ++E R+S +T + L +++ D+
Sbjct: 22285 ITCKAGSPFTIDVPISGRPAPKVTW-KLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDS 22343
Query: 127 G-YFQCVA-TNGKEVVSSTGVLFVKFGP 152
G YF + T G + S T V+ + GP
Sbjct: 22344 GRYFLTLENTAGVKTFSVTVVVIGRPGP 22371
Score = 30.0 bits (66), Expect = 3.8
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 71 LGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQ 130
+G +A C VS + T W K+ + + + P+ F + +L I ++ +D G +
Sbjct: 4760 VGSSAIFECLVSPSTAITT-WMKDGSNIRESPKH-RFIADGKDRKLHIIDVQLSDAGEYT 4817
Query: 131 CVATNGKEVVSSTGVLFVK 149
CV G + +ST L V+
Sbjct: 4818 CVLRLGNKEKTSTAKLVVE 4836
Score = 29.6 bits (65), Expect = 4.9
Identities = 22/97 (22%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
+ + +T G+ A +SG P P I W+K + ++ + F L +
Sbjct: 3197 QELQPVTVQSGKPARFCAVISGRPQPKISWYKEE-QLLSTGFKCKFLHDGQEYTLLLIEA 3255
Query: 122 DTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
D + C A N V +++ L V+ P SP
Sbjct: 3256 FPEDAAVYTCEAKNDYGVATTSASLSVEV--PEVVSP 3290
Score = 29.6 bits (65), Expect = 4.9
Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
Query: 72 GQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQC 131
G + L G P PT W K D+ + R +T S L + N + D G +
Sbjct: 22000 GASIRLFIAYQGRPTPTAVWSKPDSNL---SLRADIHTTDSFSTLTVENCNRNDAGKYTL 22056
Query: 132 VATN--GKEVVSSTGVLFVKFGPP 153
N G + ++ T + GPP
Sbjct: 22057 TVENNSGSKSITFTVKVLDTPGPP 22080
Score = 29.6 bits (65), Expect = 4.9
Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 70 SLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLD-TTDTGY 128
++G T LH G P P + WF + ++Q ++ +T + + L ++N+ T G
Sbjct: 24269 AVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK 24327
Query: 129 FQCVATN 135
++ +N
Sbjct: 24328 YKVQLSN 24334
Score = 29.3 bits (64), Expect = 6.4
Identities = 14/59 (23%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 77 LHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATN 135
L + G P P++ W K + P+ + R+S S+ + L + + +D G + N
Sbjct: 13630 LKIPIKGKPAPSVSWKKGEDPLATD-TRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13687
Score = 28.9 bits (63), Expect = 8.4
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 12/96 (12%)
Query: 72 GQTAELHCKVSGNPPPTIRWFK-------NDAPVVQEP--RRLSFRSTIYGSRLRIRNLD 122
G + K+ G P PT+ WFK N PV+ + +L T L I
Sbjct: 9759 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDT---CTLVIPQSR 9815
Query: 123 TTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASP 158
+DTG + A N S L V P P P
Sbjct: 9816 RSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGP 9851
Score = 28.9 bits (63), Expect = 8.4
Identities = 15/74 (20%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 62 EPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNL 121
E + + G++ + V G P P + WFK D +++ + + + L +R+
Sbjct: 21591 EYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGSTSLFVRDA 21649
Query: 122 DTTDTGYFQCVATN 135
G + A N
Sbjct: 21650 TRDHRGVYTVEAKN 21663
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,716,244
Number of Sequences: 37866
Number of extensions: 852689
Number of successful extensions: 3849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 1990
Number of HSP's gapped (non-prelim): 1459
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.