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Search of human proteins with 55770844
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55770844 catenin, alpha 1 [Homo sapiens]
(906 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55770844 catenin, alpha 1 [Homo sapiens] 1739 0.0
gi|55770846 catenin, alpha 2 [Homo sapiens] 1434 0.0
gi|188497718 catenin, alpha 3 [Homo sapiens] 1044 0.0
gi|188497716 catenin, alpha 3 [Homo sapiens] 1044 0.0
gi|4507877 vinculin isoform VCL [Homo sapiens] 181 2e-45
gi|4503129 catenin, alpha-like 1 [Homo sapiens] 166 7e-41
gi|7669550 vinculin isoform meta-VCL [Homo sapiens] 114 5e-25
gi|32698688 citron [Homo sapiens] 50 1e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 46 1e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 46 1e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 46 1e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 46 1e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 46 1e-04
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 42 0.002
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 42 0.003
gi|110611228 utrophin [Homo sapiens] 42 0.003
gi|223029410 talin 1 [Homo sapiens] 41 0.004
gi|31982906 cingulin-like 1 [Homo sapiens] 40 0.008
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 39 0.022
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 38 0.037
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 38 0.037
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 38 0.049
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 38 0.049
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 38 0.049
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 37 0.083
gi|56550043 sarcolemma associated protein [Homo sapiens] 37 0.083
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 36 0.14
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 36 0.14
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 36 0.14
gi|33946313 ninein isoform 4 [Homo sapiens] 36 0.19
>gi|55770844 catenin, alpha 1 [Homo sapiens]
Length = 906
Score = 1739 bits (4505), Expect = 0.0
Identities = 906/906 (100%), Positives = 906/906 (100%)
Query: 1 MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHV 60
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHV
Sbjct: 1 MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHV 60
Query: 61 LAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVK 120
LAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVK
Sbjct: 61 LAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVK 120
Query: 121 RGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL 180
RGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
Sbjct: 121 RGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL 180
Query: 181 KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKAN 240
KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKAN
Sbjct: 181 KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKAN 240
Query: 241 RDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEER 300
RDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEER
Sbjct: 241 RDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEER 300
Query: 301 FRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKER 360
FRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKER
Sbjct: 301 FRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKER 360
Query: 361 SDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYA 420
SDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYA
Sbjct: 361 SDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYA 420
Query: 421 QVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLA 480
QVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLA
Sbjct: 421 QVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLA 480
Query: 481 QENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDR 540
QENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDR
Sbjct: 481 QENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDR 540
Query: 541 TAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSS 600
TAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSS
Sbjct: 541 TAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSS 600
Query: 601 DPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTED 660
DPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTED
Sbjct: 601 DPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTED 660
Query: 661 DQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMC 720
DQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMC
Sbjct: 661 DQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMC 720
Query: 721 MIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYL 780
MIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYL
Sbjct: 721 MIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYL 780
Query: 781 QRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVAS 840
QRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVAS
Sbjct: 781 QRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVAS 840
Query: 841 TKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEF 900
TKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEF
Sbjct: 841 TKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEF 900
Query: 901 KAMDSI 906
KAMDSI
Sbjct: 901 KAMDSI 906
>gi|55770846 catenin, alpha 2 [Homo sapiens]
Length = 905
Score = 1434 bits (3712), Expect = 0.0
Identities = 741/899 (82%), Positives = 820/899 (91%), Gaps = 4/899 (0%)
Query: 9 INFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQA 68
I KWDPKSLEIRTL VERLLEPLVTQVTTLVNT++KGPS KK+GRSKKAHVLAASVEQA
Sbjct: 8 IILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQA 67
Query: 69 TENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAA 128
T+NFLEKG++IAKESQ LKEELVAAVEDVRKQG+ M+ A+ EFADDPCSSVKRG MVRAA
Sbjct: 68 TQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAA 127
Query: 129 RALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLN 188
RALLSAVTRLLILADMADV +LL LK+VE+ + ++NA NEQDL ++K E+ KLN
Sbjct: 128 RALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLN 187
Query: 189 IMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQL 248
+AA+RQQELKD RD+MAAARG L+KN +LYTASQA L+HPDVAA +ANRD ++KQ+
Sbjct: 188 YVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQV 247
Query: 249 QQAVTGISNAAQATA-SDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEE 307
Q+A+ GISNAAQAT+ +D+A H G G ELA ALN FD +II+DP++FSE RFRPSLEE
Sbjct: 248 QEAIAGISNAAQATSPTDEAKGHTGIG--ELAAALNEFDNKIILDPMTFSEARFRPSLEE 305
Query: 308 RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSA 367
RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYM N GRKE+ D LN A
Sbjct: 306 RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIA 365
Query: 368 IDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHA 427
IDKMTKKTRDLRRQLRKAVMDH+SDSFLETNVPLLVLIEAAK+GNEKEVKEYAQVFREHA
Sbjct: 366 IDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHA 425
Query: 428 NKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLF 487
NKL+EVANLACSISNNEEGVKLVRM+A+Q+++LCPQVINAAL LAA+PQSK+AQ+NMD+F
Sbjct: 426 NKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVF 485
Query: 488 KEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRG 547
K+QWEKQVRVLT+AVDDITS+DDFL+VSENHILEDVNKCVIALQE DVD LDRTAGAIRG
Sbjct: 486 KDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRG 545
Query: 548 RAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMD 607
RAARVIH++ +EM+NYE GVYTEKVLEATKLLS TVMPRF EQVE A+EALS++ QP +
Sbjct: 546 RAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFE 605
Query: 608 ENEFIDASRLVYDGIRDIRKAVLMIRTPEEL-DDSDFETEDFDVRSRTSVQTEDDQLIAG 666
ENEFIDASRLVYDG+RDIRKAVLMIRTPEEL DDSDFE ED+DVRSRTSVQTEDDQLIAG
Sbjct: 606 ENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAG 665
Query: 667 QSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEM 726
QSARAIMAQLPQE+KAKIAEQV F +EKSKLDAEV+KWDDSGNDIIVLAKQMCMIMMEM
Sbjct: 666 QSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEM 725
Query: 727 TDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALY 786
TDFTRGKGPLKNTSDVI+AAKKIAEAGSRMDKL R +AD CPDSACKQDLLAYLQRIALY
Sbjct: 726 TDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALY 785
Query: 787 CHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKS 846
CHQLNICSKVKAEVQNLGGEL+VSG+DSA SLIQAAKNLMNAVV TVKASYVASTKYQK
Sbjct: 786 CHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKV 845
Query: 847 QGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFKAMDS 905
G A++N P VSWKMKAPEKKPLVKREK +E QT+++R SQKKH++PVQALSEFKAMDS
Sbjct: 846 YGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALSEFKAMDS 904
>gi|188497718 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 1044 bits (2699), Expect = 0.0
Identities = 531/893 (59%), Positives = 684/893 (76%), Gaps = 9/893 (1%)
Query: 9 INFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQA 68
I DP+ L+++T VE+LLEPL+ QVTTLVN + PS++K+GRSK+A VL ASVE+A
Sbjct: 7 ITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNC-PQNPSSRKKGRSKRASVLLASVEEA 65
Query: 69 TENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAA 128
T N L+KG+KIA+E+ LK+EL A++E+VRK+ + +K +A F DDPC KR +V+AA
Sbjct: 66 TWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAA 125
Query: 129 RALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLN 188
RALL+AVTRLLILADM DV LL + + L+N N+ DL Y+ L E++ L+
Sbjct: 126 RALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLD 185
Query: 189 IMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQL 248
+A KRQQ+LK RD++A AR L++N P+L++ ACL+H DVA+ KA++D + +++
Sbjct: 186 YLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEI 245
Query: 249 QQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEER 308
Q A+ ISNA+Q + L AL+ + I+++PL+ +EE RPSLE+R
Sbjct: 246 QNALNVISNASQGIQNMTTPPEPQAA--TLGSALDELENLIVLNPLTVTEEEIRPSLEKR 303
Query: 309 LESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAI 368
LE+IISGAAL+ADSSCTRD RERI+AECNA+RQALQDLLSEYM NAG+KERS+ LN A+
Sbjct: 304 LEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIAL 363
Query: 369 DKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHAN 428
D M KKTRDLRRQLRKA++DHVSDSFL+T VPLLVLIEAAKNG EKE+KEYA +F EH +
Sbjct: 364 DNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTS 423
Query: 429 KLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFK 488
+L+EVANLACS+S NE+G+K+V+++A+ LE LCPQ+INAALALAA+P+S+ + M+++K
Sbjct: 424 RLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYK 483
Query: 489 EQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGR 548
WE + VLT+AVDDITSIDDFLAVSE+HILEDVNKC+IAL+++D D LDR AGAIRGR
Sbjct: 484 RTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGR 543
Query: 549 AARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDE 608
AARV H+VT EMD+YEPG YTE V+ L++TV+P F QV A+EALS +D+
Sbjct: 544 AARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDD 603
Query: 609 NEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQS 668
N+F+D S+ +YD I DIR +V+MIRTPEEL+D E+ +VRS TS+QTE G++
Sbjct: 604 NQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTE------GKT 657
Query: 669 ARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTD 728
RA M QLP+ +K KIAEQVA F++ KSKLDAE+ WDD+ NDIIVLAK MCMIMMEMTD
Sbjct: 658 DRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTD 717
Query: 729 FTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCH 788
FTRGKGPLK+T+DVI AAK I+E+GSRMD L R IA+ CPD +CKQDLLAYL++I Y H
Sbjct: 718 FTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSH 777
Query: 789 QLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQG 848
QL ICS+VKAE+QNLGGEL++S +DS SLIQAAKNLMNAVVQTVK SY+ASTK + Q
Sbjct: 778 QLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQS 837
Query: 849 MASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFK 901
A P V W+MKAP KKPL+KREK +ET ++R S KK ++P+Q +SEF+
Sbjct: 838 PAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFR 890
>gi|188497716 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 1044 bits (2699), Expect = 0.0
Identities = 531/893 (59%), Positives = 684/893 (76%), Gaps = 9/893 (1%)
Query: 9 INFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQA 68
I DP+ L+++T VE+LLEPL+ QVTTLVN + PS++K+GRSK+A VL ASVE+A
Sbjct: 7 ITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNC-PQNPSSRKKGRSKRASVLLASVEEA 65
Query: 69 TENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAA 128
T N L+KG+KIA+E+ LK+EL A++E+VRK+ + +K +A F DDPC KR +V+AA
Sbjct: 66 TWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAA 125
Query: 129 RALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLN 188
RALL+AVTRLLILADM DV LL + + L+N N+ DL Y+ L E++ L+
Sbjct: 126 RALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLD 185
Query: 189 IMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQL 248
+A KRQQ+LK RD++A AR L++N P+L++ ACL+H DVA+ KA++D + +++
Sbjct: 186 YLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEI 245
Query: 249 QQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEER 308
Q A+ ISNA+Q + L AL+ + I+++PL+ +EE RPSLE+R
Sbjct: 246 QNALNVISNASQGIQNMTTPPEPQAA--TLGSALDELENLIVLNPLTVTEEEIRPSLEKR 303
Query: 309 LESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAI 368
LE+IISGAAL+ADSSCTRD RERI+AECNA+RQALQDLLSEYM NAG+KERS+ LN A+
Sbjct: 304 LEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIAL 363
Query: 369 DKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHAN 428
D M KKTRDLRRQLRKA++DHVSDSFL+T VPLLVLIEAAKNG EKE+KEYA +F EH +
Sbjct: 364 DNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTS 423
Query: 429 KLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFK 488
+L+EVANLACS+S NE+G+K+V+++A+ LE LCPQ+INAALALAA+P+S+ + M+++K
Sbjct: 424 RLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYK 483
Query: 489 EQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGR 548
WE + VLT+AVDDITSIDDFLAVSE+HILEDVNKC+IAL+++D D LDR AGAIRGR
Sbjct: 484 RTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGR 543
Query: 549 AARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDE 608
AARV H+VT EMD+YEPG YTE V+ L++TV+P F QV A+EALS +D+
Sbjct: 544 AARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDD 603
Query: 609 NEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQS 668
N+F+D S+ +YD I DIR +V+MIRTPEEL+D E+ +VRS TS+QTE G++
Sbjct: 604 NQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTE------GKT 657
Query: 669 ARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTD 728
RA M QLP+ +K KIAEQVA F++ KSKLDAE+ WDD+ NDIIVLAK MCMIMMEMTD
Sbjct: 658 DRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTD 717
Query: 729 FTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCH 788
FTRGKGPLK+T+DVI AAK I+E+GSRMD L R IA+ CPD +CKQDLLAYL++I Y H
Sbjct: 718 FTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSH 777
Query: 789 QLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQG 848
QL ICS+VKAE+QNLGGEL++S +DS SLIQAAKNLMNAVVQTVK SY+ASTK + Q
Sbjct: 778 QLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQS 837
Query: 849 MASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFK 901
A P V W+MKAP KKPL+KREK +ET ++R S KK ++P+Q +SEF+
Sbjct: 838 PAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFR 890
>gi|4507877 vinculin isoform VCL [Homo sapiens]
Length = 1066
Score = 181 bits (460), Expect = 2e-45
Identities = 153/550 (27%), Positives = 246/550 (44%), Gaps = 39/550 (7%)
Query: 330 RERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDH 389
R+ ++A+C+ V Q L G ++ AL S + K DL+ ++++A+
Sbjct: 538 RQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLK---DLKARMQEAMTQE 594
Query: 390 VSDSFLETNVPLLVLIEAAKNG----NEKEV-KEYAQVFREHANKLIEVANLACSISN-N 443
VSD F +T P+ +L AA N +EV E A F H+ KL A A ++ N
Sbjct: 595 VSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTAN 654
Query: 444 EEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVD 503
+ V+ ++ S L PQV++AA L P ++ A E+ + K QW V +T VD
Sbjct: 655 KSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVD 714
Query: 504 DITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNY 563
+ L SE I +D++KC +A+ L A +I RA R++ V E++N
Sbjct: 715 EAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENS 774
Query: 564 EPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIR 623
E + E V A+ LS T+ P + +A++ + + P + F+D+ + +
Sbjct: 775 EDPKFREAVKAASDELSKTISPMVMD-----AKAVAGNISDPGLQKSFLDSGYRILGAVA 829
Query: 624 DIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAK 683
+R+A P+E D + +R + L G+ P+E+ +
Sbjct: 830 KVREAF----QPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGE-VPPPRPPPPEEKDEE 884
Query: 684 IAEQVAS------FQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLK 737
EQ A +L E KW GNDII AK+M ++M EM+ RG K
Sbjct: 885 FPEQKAGEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTK 944
Query: 738 NTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVK 797
+I AK IA+A + +L + +A C D + +LL +RI QL I S VK
Sbjct: 945 RA--LIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVK 1002
Query: 798 AEVQNLGGELVVSGVDSAMS---LIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNL 854
A + G +S +S + L+ A+NLM +V +TV+ + AS K + G
Sbjct: 1003 A---TMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGF----- 1054
Query: 855 PAVSWKMKAP 864
+ W K P
Sbjct: 1055 -TLRWVRKTP 1063
Score = 76.6 bits (187), Expect = 9e-14
Identities = 85/378 (22%), Positives = 166/378 (43%), Gaps = 26/378 (6%)
Query: 22 TLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAK 81
T +E +LEP+ Q++ LV + +G + K A V A+V+ A N + G + +
Sbjct: 6 TRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPV--AAVQAAVSNLVRVGKETVQ 63
Query: 82 --ESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLL 139
E Q LK ++ A V + AA DP S R ++ +R +LS + LL
Sbjct: 64 TTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLL 123
Query: 140 ILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELK 199
+ D A+V K++ K + + + +DL K L P + K+ M +RQQEL
Sbjct: 124 LTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELT 183
Query: 200 DVGHRDQMAAARGILQKNVPILYTASQACL-----QHPDVAAYKANRDLIYKQLQQAVTG 254
HR + + +++ +P+L +A + + ++ + NR+ +++ +
Sbjct: 184 HQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINE 243
Query: 255 ISNAAQATASDDASQHQGGGGGELAYALNNFDKQI------IVDPLSFSEERFRPSLEER 308
I Q T+ D+ + AL + D ++ + DP + + + E+
Sbjct: 244 IIRVLQLTSWDE-DAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGD----AGEQA 298
Query: 309 LESIISGAALMADSSCTRDDRRERIVAECNAVRQ---ALQDLLSEYMGNAG-RKERSDAL 364
+ I+ A + + C +RRE I+ C + Q + DL + G++ +++ +
Sbjct: 299 IRQILDEAGKVGE-LCAGKERRE-ILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQV 356
Query: 365 NSAIDKMTKKTRDLRRQL 382
+ +D +T K + R+L
Sbjct: 357 SQGLDVLTAKVENAARKL 374
>gi|4503129 catenin, alpha-like 1 [Homo sapiens]
Length = 734
Score = 166 bits (421), Expect = 7e-41
Identities = 139/520 (26%), Positives = 246/520 (47%), Gaps = 30/520 (5%)
Query: 6 AGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKA-HVLAAS 64
+G+ F D LEI+T +VE+ L PLV+Q+TTL+N + KK ++ +A + +
Sbjct: 19 SGSSGFALD-SGLEIKTRSVEQTLLPLVSQITTLINHKD---NTKKSDKTLQAIQRVGQA 74
Query: 65 VEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAG-------EFADDPCS 117
V A F++ G+ IA E+ LKEE+ A + ++ G+ + A E
Sbjct: 75 VNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITI 134
Query: 118 SVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQY 177
+ +++AAR LLS+VT++L+LAD + +++ V + +L + Q+ +
Sbjct: 135 FTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIF 194
Query: 178 KALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAY 237
E+ + ++ RQ +LKD + +MAAAR +L+K +L TAS+ CL+HP+ +
Sbjct: 195 SQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESA 254
Query: 238 KANRDLIYKQLQQA---VTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQI--IVD 292
N++ ++ +++ A V I + D S + + F I + +
Sbjct: 255 HKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSI------SIFTGIKEFKMNIEALRE 308
Query: 293 PLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYM 352
L F + +L LE I+ DS+ T + RERI+ R LQ L+S ++
Sbjct: 309 NLYFQS---KENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWI 365
Query: 353 GNAGRKERS--DALNSAIDKMTKKTRDLRRQLRKAVMDHVSD--SFLETNVPLLVLIEAA 408
+K +S + L +I K++ +L+++L +D + +V L L
Sbjct: 366 QAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTG 425
Query: 409 KNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAA 468
GN + + EYA E +L+E L IS E + + Q+I+AA
Sbjct: 426 VEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAA 485
Query: 469 LALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSI 508
L P SK+A+EN+D+F E WE Q+ ++ + +I +
Sbjct: 486 ETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDV 525
Score = 62.0 bits (149), Expect = 2e-09
Identities = 45/166 (27%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Query: 679 EQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKN 738
E++AKIA+ S D E+ KW+D N+I+ + M + + FTRG+GPLK
Sbjct: 560 EEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKT 619
Query: 739 TSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKA 798
+ D+I + A G ++ + + D K LL + ++ CHQL +K
Sbjct: 620 SQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDD-KLMLLLEINKLIPLCHQLQTVTKTSL 678
Query: 799 EVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQ 844
+ V VD I +++M +VQ + Y K Q
Sbjct: 679 Q------NKVFLKVDKC---ITKTRSMMALLVQLLSLCYKLLKKLQ 715
>gi|7669550 vinculin isoform meta-VCL [Homo sapiens]
Length = 1134
Score = 114 bits (284), Expect = 5e-25
Identities = 85/305 (27%), Positives = 144/305 (47%), Gaps = 14/305 (4%)
Query: 330 RERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDH 389
R+ ++A+C+ V Q L G ++ AL S + K DL+ ++++A+
Sbjct: 538 RQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLK---DLKARMQEAMTQE 594
Query: 390 VSDSFLETNVPLLVLIEAAKNG----NEKEV-KEYAQVFREHANKLIEVANLACSISN-N 443
VSD F +T P+ +L AA N +EV E A F H+ KL A A ++ N
Sbjct: 595 VSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTAN 654
Query: 444 EEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVD 503
+ V+ ++ S L PQV++AA L P ++ A E+ + K QW V +T VD
Sbjct: 655 KSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVD 714
Query: 504 DITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNY 563
+ L SE I +D++KC +A+ L A +I RA R++ V E++N
Sbjct: 715 EAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENS 774
Query: 564 EPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIR 623
E + E V A+ LS T+ P + +A++ + + P + F+D+ + +
Sbjct: 775 EDPKFREAVKAASDELSKTISPMVMD-----AKAVAGNISDPGLQKSFLDSGYRILGAVA 829
Query: 624 DIRKA 628
+R+A
Sbjct: 830 KVREA 834
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 14/170 (8%)
Query: 698 LDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMD 757
L E +KW GNDII AK+M ++M EM+ RG K +I AK IA+A +
Sbjct: 973 LHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRA--LIQCAKDIAKASDEVT 1030
Query: 758 KLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMS 817
+L + +A C D + +LL +RI QL I S VKA + G +S +S +
Sbjct: 1031 RLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKA---TMLGRTNISDEESEQA 1087
Query: 818 ---LIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKAP 864
L+ A+NLM +V +TV+ + AS K + G + W K P
Sbjct: 1088 TEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGF------TLRWVRKTP 1131
Score = 76.6 bits (187), Expect = 9e-14
Identities = 85/378 (22%), Positives = 166/378 (43%), Gaps = 26/378 (6%)
Query: 22 TLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAK 81
T +E +LEP+ Q++ LV + +G + K A V A+V+ A N + G + +
Sbjct: 6 TRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPV--AAVQAAVSNLVRVGKETVQ 63
Query: 82 --ESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLL 139
E Q LK ++ A V + AA DP S R ++ +R +LS + LL
Sbjct: 64 TTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLL 123
Query: 140 ILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELK 199
+ D A+V K++ K + + + +DL K L P + K+ M +RQQEL
Sbjct: 124 LTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELT 183
Query: 200 DVGHRDQMAAARGILQKNVPILYTASQACL-----QHPDVAAYKANRDLIYKQLQQAVTG 254
HR + + +++ +P+L +A + + ++ + NR+ +++ +
Sbjct: 184 HQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINE 243
Query: 255 ISNAAQATASDDASQHQGGGGGELAYALNNFDKQI------IVDPLSFSEERFRPSLEER 308
I Q T+ D+ + AL + D ++ + DP + + + E+
Sbjct: 244 IIRVLQLTSWDE-DAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGD----AGEQA 298
Query: 309 LESIISGAALMADSSCTRDDRRERIVAECNAVRQ---ALQDLLSEYMGNAG-RKERSDAL 364
+ I+ A + + C +RRE I+ C + Q + DL + G++ +++ +
Sbjct: 299 IRQILDEAGKVGE-LCAGKERRE-ILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQV 356
Query: 365 NSAIDKMTKKTRDLRRQL 382
+ +D +T K + R+L
Sbjct: 357 SQGLDVLTAKVENAARKL 374
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 49.7 bits (117), Expect = 1e-05
Identities = 133/667 (19%), Positives = 265/667 (39%), Gaps = 108/667 (16%)
Query: 165 RNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTA 224
+ + E+ L I+ K L+ DK + K +QE+ + HR + QK V + +
Sbjct: 443 KTSSMEKKLLIKSKELQDSQDKCH----KMEQEMTRL-HRRVSEVEAVLSQKEVELKASE 497
Query: 225 SQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNN 284
+Q L D+A Y + + L+QA +S DD + +L + +
Sbjct: 498 TQRSLLEQDLATYITECSSLKRSLEQARMEVSQ------EDDKAL-------QLLHDIRE 544
Query: 285 FDKQIIVDPLSFSEERFRPSLEE------RLESIISGAALMAD--SSCTRDDRR-----E 331
+++ E+ ++ +EE +LE + A +D S R+ R +
Sbjct: 545 QSRKL----QEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFK 600
Query: 332 RIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVS 391
R EC +D +G + E+ +A + K ++L+ +L KAV
Sbjct: 601 RKATECQHKLLKAKDQGKPEVGEYAKLEKINA------EQQLKIQELQEKLEKAVKASTE 654
Query: 392 DSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHAN-----KLIEVANLACSISNNEEG 446
+ L N I AK E+E+++ RE ++ KL+E L EE
Sbjct: 655 ATELLQN------IRQAKERAERELEKLQN--REDSSEGIRKKLVEAEEL-------EEK 699
Query: 447 VKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQ-WEKQVRVLTDAVD-D 504
+ ++SA LE Q KEQ +E++++VL + + D
Sbjct: 700 HREAQVSAQHLEVHLKQ------------------------KEQHYEEKIKVLDNQIKKD 735
Query: 505 ITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYE 564
+ + + + H E K I ++K + ++ IR R++ + +
Sbjct: 736 LADKETLENMMQRHEEEAHEKGKILSEQKAM--INAMDSKIRSLEQRIVELSEANKLAAN 793
Query: 565 PGVYTEKVLEATK-LLSNTVMPRFTEQVEAA-VEALSSDPAQPMDENEFIDASRLVYDGI 622
++T++ ++A + ++S +F + +A +EA + + +++ D S D
Sbjct: 794 SSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHS----DKN 849
Query: 623 RDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKA 682
R + + E ++ E + + S+Q + QL A Q+ARA + ++ K
Sbjct: 850 RLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKT 909
Query: 683 KIAEQVASFQEEKSKLDAE----VSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKN 738
++ E A +EE L A K+D N V+ + ++ T L N
Sbjct: 910 ELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITD----LEEQLNQLTEDNAELNN 965
Query: 739 TSDVISAAKKIAEAGSRMDKLG--RTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKV 796
+ +S K++ EA D++ R+ DH ++++ Q+ + + C+ +
Sbjct: 966 QNFYLS--KQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALK-TTCTML 1022
Query: 797 KAEVQNL 803
+ +V +L
Sbjct: 1023 EEQVMDL 1029
Score = 32.7 bits (73), Expect = 1.6
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 634 TPEELDDSDFETEDFDVRSRTSV-QTEDDQLIAGQSARAIMAQLPQEQKAKIA-EQVASF 691
T EL + +DF+VRS + Q++ ++ I A ++KA +A EQV+ F
Sbjct: 83 TIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFF 142
Query: 692 QEEKSKLDAEVSKW 705
+EE++ L S W
Sbjct: 143 EEERNILSRSTSPW 156
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 46.2 bits (108), Expect = 1e-04
Identities = 133/656 (20%), Positives = 253/656 (38%), Gaps = 110/656 (16%)
Query: 168 GNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARG---ILQKNVPILYT- 223
G DL Q L+ ++D+L + AK+++EL Q A ARG L KN +
Sbjct: 1062 GETTDLQDQIAELQAQIDELKLQLAKKEEEL-------QGALARGDDETLHKNNALKVVR 1114
Query: 224 --ASQACLQHPDVAAYKANRDLIYKQ---LQQAVTGISNAAQATASDDASQHQ-----GG 273
+Q D + KA+R+ KQ L + + + + T A+Q +
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174
Query: 274 GGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTR---DDRR 330
EL AL K + +R +LEE E + A+ + +
Sbjct: 1175 EVAELKKALEEETKNHEAQ-IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDN 1233
Query: 331 ERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHV 390
+ + E ++Q A + + L++ + ++ K + R LR + +
Sbjct: 1234 KELACEVKVLQQV----------KAESEHKRKKLDAQVQELHAKVSEGDR-LRVELAEKA 1282
Query: 391 SDSFLETNVPLLVLIEAAKNG---------NEKEVKEYAQVFREHANKLIEVANLACSIS 441
S E + +L EA K G E ++++ ++ +E + + NL+ I
Sbjct: 1283 SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKL---NLSSRIR 1339
Query: 442 NNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQ------------ENMDLFKE 489
EE ++ + E + LAL QS+LA E+++ K+
Sbjct: 1340 QLEEEKNSLQEQQEEEEEARKNLEKQVLAL----QSQLADTKKKVDDDLGTIESLEEAKK 1395
Query: 490 QWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQ---------EKDVDGLDR 540
+ K L+ +++ D L ++N + ++++ + L EK D+
Sbjct: 1396 KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ 1455
Query: 541 TAGAIRGRAARVIHVVTSEMDNYEPGVYTE--KVLEATKLLSNTVMPRFTEQVEAAVEAL 598
+ +AR E D E + K L + L + + E+ E + L
Sbjct: 1456 LLAEEKSISAR----YAEERDRAEAEAREKETKALSLARALEEALEAK--EEFERQNKQL 1509
Query: 599 SSDPAQPMDENEFIDASRLVYD---GIRDIRKAVLMIRTP-EELDDSDFETEDFDVRSRT 654
+D M + D + V++ R + + V +RT EEL+D TED +R
Sbjct: 1510 RADMEDLMSSKD--DVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1567
Query: 655 SV----------------QTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVAS---FQEEK 695
++ Q E+ + + + R + A+L E+K + A VAS + +
Sbjct: 1568 NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQR-ALAVASKKKMEIDL 1626
Query: 696 SKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAE 751
L+A++ + + +++I KQ+ + +M D+ R + + D I A K +E
Sbjct: 1627 KDLEAQIEAANKARDEVI---KQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 46.2 bits (108), Expect = 1e-04
Identities = 119/645 (18%), Positives = 244/645 (37%), Gaps = 82/645 (12%)
Query: 162 LKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHR--DQMAAARGILQKNVP 219
LK + G+ D Q L+ ++ +L + AK+++EL+ R D++A L+K
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK--- 1112
Query: 220 ILYTASQACLQHPDVAAYKANRDLIYKQ---LQQAVTGISNAAQATASDDASQHQ--GGG 274
I D+ + +A R+ KQ L + + + + T A+Q +
Sbjct: 1113 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1172
Query: 275 GGELAYALNNFDKQIIVDPLSFSEERFR-----PSLEERLESIISGAALMADSSCTRDDR 329
E+ D++ E R + L E+LE A + + T +
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 330 RERIVAECNAVRQALQDL----------LSEYMGNAGRKERSDA-LNSAIDKMTKKTRDL 378
+ E + QA Q++ + E ER+ A LN + K+ + +
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 379 RRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLAC 438
L +A + L +V L ++++ ++ +E + + V+
Sbjct: 1293 TGMLNEAEGKAIK---LAKDVASL----------SSQLQDTQELLQEETRQKLNVSTKLR 1339
Query: 439 SISNNEEGVK---LVRMSASQLEALCPQVINAALALAAKPQSKLAQ--ENMDLFKEQWEK 493
+ ++ M A Q +N L+ + K A E ++ K++++K
Sbjct: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
Query: 494 QVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIAL--QEKDVDGLDRTAGAIRGRAAR 551
++ LT ++ + D L ++N + ++++ V+ L Q + V L++ A
Sbjct: 1400 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
Query: 552 VIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEF 611
++ + D + + E TK LS + E +EA E ++ + +
Sbjct: 1460 EKNISSKYADERDRAEAEAREKE-TKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 612 IDASRLVYDGIRDIRKAVLMIRTP--------EELDDSDFETEDFDVRSRTSVQTEDDQL 663
+ + V + ++ K+ + T EEL+D TED +R ++Q
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----- 1571
Query: 664 IAGQSARAIMAQLPQ--EQKAKIAEQVASFQEE--------------KSKLDAEVSKWDD 707
+ GQ R + A+ Q E++ ++ Q+ ++ E K KL+ ++ +
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1631
Query: 708 SGNDII----VLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKK 748
+ I KQ+ + +M DF R + + D I A K
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 1676
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 46.2 bits (108), Expect = 1e-04
Identities = 119/645 (18%), Positives = 244/645 (37%), Gaps = 82/645 (12%)
Query: 162 LKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHR--DQMAAARGILQKNVP 219
LK + G+ D Q L+ ++ +L + AK+++EL+ R D++A L+K
Sbjct: 1063 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK--- 1119
Query: 220 ILYTASQACLQHPDVAAYKANRDLIYKQ---LQQAVTGISNAAQATASDDASQHQ--GGG 274
I D+ + +A R+ KQ L + + + + T A+Q +
Sbjct: 1120 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1179
Query: 275 GGELAYALNNFDKQIIVDPLSFSEERFR-----PSLEERLESIISGAALMADSSCTRDDR 329
E+ D++ E R + L E+LE A + + T +
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 330 RERIVAECNAVRQALQDL----------LSEYMGNAGRKERSDA-LNSAIDKMTKKTRDL 378
+ E + QA Q++ + E ER+ A LN + K+ + +
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Query: 379 RRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLAC 438
L +A + L +V L ++++ ++ +E + + V+
Sbjct: 1300 TGMLNEAEGKAIK---LAKDVASL----------SSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 439 SISNNEEGVK---LVRMSASQLEALCPQVINAALALAAKPQSKLAQ--ENMDLFKEQWEK 493
+ ++ M A Q +N L+ + K A E ++ K++++K
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406
Query: 494 QVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIAL--QEKDVDGLDRTAGAIRGRAAR 551
++ LT ++ + D L ++N + ++++ V+ L Q + V L++ A
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Query: 552 VIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEF 611
++ + D + + E TK LS + E +EA E ++ + +
Sbjct: 1467 EKNISSKYADERDRAEAEAREKE-TKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 612 IDASRLVYDGIRDIRKAVLMIRTP--------EELDDSDFETEDFDVRSRTSVQTEDDQL 663
+ + V + ++ K+ + T EEL+D TED +R ++Q
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----- 1578
Query: 664 IAGQSARAIMAQLPQ--EQKAKIAEQVASFQEE--------------KSKLDAEVSKWDD 707
+ GQ R + A+ Q E++ ++ Q+ ++ E K KL+ ++ +
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1638
Query: 708 SGNDII----VLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKK 748
+ I KQ+ + +M DF R + + D I A K
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 1683
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 46.2 bits (108), Expect = 1e-04
Identities = 119/645 (18%), Positives = 244/645 (37%), Gaps = 82/645 (12%)
Query: 162 LKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHR--DQMAAARGILQKNVP 219
LK + G+ D Q L+ ++ +L + AK+++EL+ R D++A L+K
Sbjct: 1063 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK--- 1119
Query: 220 ILYTASQACLQHPDVAAYKANRDLIYKQ---LQQAVTGISNAAQATASDDASQHQ--GGG 274
I D+ + +A R+ KQ L + + + + T A+Q +
Sbjct: 1120 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1179
Query: 275 GGELAYALNNFDKQIIVDPLSFSEERFR-----PSLEERLESIISGAALMADSSCTRDDR 329
E+ D++ E R + L E+LE A + + T +
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 330 RERIVAECNAVRQALQDL----------LSEYMGNAGRKERSDA-LNSAIDKMTKKTRDL 378
+ E + QA Q++ + E ER+ A LN + K+ + +
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Query: 379 RRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLAC 438
L +A + L +V L ++++ ++ +E + + V+
Sbjct: 1300 TGMLNEAEGKAIK---LAKDVASL----------SSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 439 SISNNEEGVK---LVRMSASQLEALCPQVINAALALAAKPQSKLAQ--ENMDLFKEQWEK 493
+ ++ M A Q +N L+ + K A E ++ K++++K
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406
Query: 494 QVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIAL--QEKDVDGLDRTAGAIRGRAAR 551
++ LT ++ + D L ++N + ++++ V+ L Q + V L++ A
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Query: 552 VIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEF 611
++ + D + + E TK LS + E +EA E ++ + +
Sbjct: 1467 EKNISSKYADERDRAEAEAREKE-TKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 612 IDASRLVYDGIRDIRKAVLMIRTP--------EELDDSDFETEDFDVRSRTSVQTEDDQL 663
+ + V + ++ K+ + T EEL+D TED +R ++Q
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----- 1578
Query: 664 IAGQSARAIMAQLPQ--EQKAKIAEQVASFQEE--------------KSKLDAEVSKWDD 707
+ GQ R + A+ Q E++ ++ Q+ ++ E K KL+ ++ +
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1638
Query: 708 SGNDII----VLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKK 748
+ I KQ+ + +M DF R + + D I A K
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 1683
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 46.2 bits (108), Expect = 1e-04
Identities = 119/645 (18%), Positives = 244/645 (37%), Gaps = 82/645 (12%)
Query: 162 LKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHR--DQMAAARGILQKNVP 219
LK + G+ D Q L+ ++ +L + AK+++EL+ R D++A L+K
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK--- 1112
Query: 220 ILYTASQACLQHPDVAAYKANRDLIYKQ---LQQAVTGISNAAQATASDDASQHQ--GGG 274
I D+ + +A R+ KQ L + + + + T A+Q +
Sbjct: 1113 IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1172
Query: 275 GGELAYALNNFDKQIIVDPLSFSEERFR-----PSLEERLESIISGAALMADSSCTRDDR 329
E+ D++ E R + L E+LE A + + T +
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 330 RERIVAECNAVRQALQDL----------LSEYMGNAGRKERSDA-LNSAIDKMTKKTRDL 378
+ E + QA Q++ + E ER+ A LN + K+ + +
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 379 RRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLAC 438
L +A + L +V L ++++ ++ +E + + V+
Sbjct: 1293 TGMLNEAEGKAIK---LAKDVASL----------SSQLQDTQELLQEETRQKLNVSTKLR 1339
Query: 439 SISNNEEGVK---LVRMSASQLEALCPQVINAALALAAKPQSKLAQ--ENMDLFKEQWEK 493
+ ++ M A Q +N L+ + K A E ++ K++++K
Sbjct: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
Query: 494 QVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIAL--QEKDVDGLDRTAGAIRGRAAR 551
++ LT ++ + D L ++N + ++++ V+ L Q + V L++ A
Sbjct: 1400 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
Query: 552 VIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEF 611
++ + D + + E TK LS + E +EA E ++ + +
Sbjct: 1460 EKNISSKYADERDRAEAEAREKE-TKALS--LARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 612 IDASRLVYDGIRDIRKAVLMIRTP--------EELDDSDFETEDFDVRSRTSVQTEDDQL 663
+ + V + ++ K+ + T EEL+D TED +R ++Q
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----- 1571
Query: 664 IAGQSARAIMAQLPQ--EQKAKIAEQVASFQEE--------------KSKLDAEVSKWDD 707
+ GQ R + A+ Q E++ ++ Q+ ++ E K KL+ ++ +
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1631
Query: 708 SGNDII----VLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKK 748
+ I KQ+ + +M DF R + + D I A K
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 1676
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 42.4 bits (98), Expect = 0.002
Identities = 70/355 (19%), Positives = 139/355 (39%), Gaps = 17/355 (4%)
Query: 364 LNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEK--EVKEYAQ 421
LNS I + R Q+ + DH+ + F +++ LL I+A K N+K + E +
Sbjct: 1504 LNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELE 1563
Query: 422 VFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQ 481
E A L + + NNE + + R+ A + + A K Q+ +
Sbjct: 1564 KSNECAEMLKQKVE-ELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFK 1622
Query: 482 ENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKC-----VIALQEKDVD 536
+ + E KQ + D I +++ LA S+N + E KC +I +K+V
Sbjct: 1623 DQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVR 1682
Query: 537 GLDRTAGAIRGRAAR-VIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAV 595
L+ A + R V + E +KV + L T+ + T +
Sbjct: 1683 NLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHL--KTIEEQMTHRKMVLF 1740
Query: 596 EALSSDPAQPMDE-----NEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDV 650
+ S Q +E + +++ + + I IR + ++ + + + ++
Sbjct: 1741 QEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNI 1800
Query: 651 RS-RTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSK 704
+ +Q +Q+ GQ A Q Q+ + ++ Q + K K+D ++ +
Sbjct: 1801 KELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKE 1855
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 41.6 bits (96), Expect = 0.003
Identities = 91/478 (19%), Positives = 197/478 (41%), Gaps = 44/478 (9%)
Query: 236 AYKANRDLIYKQLQQ---AVTGISNAAQATASD-----DASQHQGGGGGELAYALNNFDK 287
A+ + + +QL++ A +++A Q++ D + + + G EL AL+ +
Sbjct: 1308 AFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1367
Query: 288 QIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDL 347
++ + ++ +R E + +A +++ E + A+C ++ + Q L
Sbjct: 1368 EV-----AQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL 1422
Query: 348 LSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSD--SFLETNVPLLVLI 405
E ER+++L +A+DK + + + + + ++ + L+ + L +
Sbjct: 1423 QGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTEL 1482
Query: 406 EAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLE------A 459
KN E+ + + V RE+ N E+A+L I+ N + + + S Q+E
Sbjct: 1483 FKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQ 1542
Query: 460 LCPQVINAAL----ALAAKPQSKLAQENMDLFK------EQWEKQVRVLTDAVDDITSID 509
L + AAL A + Q +L Q ++ + E+ E+ R V+ + S
Sbjct: 1543 LALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL 1602
Query: 510 DFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYT 569
D S N + K L E ++ + + A R A + H+ + + + ++
Sbjct: 1603 DAEVRSRNEAIRLKKKMEGDLNEIEI----QLSHANRQAAETLKHLRSVQGQLKDTQLHL 1658
Query: 570 EKVLEATKLLSN--TVMPRFTEQVEAAVEAL-----SSDPAQPMDENEFIDASRLVYDGI 622
+ L + L ++ R ++A VE L ++ A+ + E E +D++ V +
Sbjct: 1659 DDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV-QLL 1717
Query: 623 RDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQ 680
+++ + E D ++E D SR + E+ A A + +L +EQ
Sbjct: 1718 HTQNTSLIHTKKKLETDLMQLQSEVEDA-SRDARNAEEKAKKAITDAAMMAEELKKEQ 1774
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 41.6 bits (96), Expect = 0.003
Identities = 73/337 (21%), Positives = 138/337 (40%), Gaps = 45/337 (13%)
Query: 577 KLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFI-DASRLVYDG--IRDIRKAVLMIR 633
++ S V+P T+ V A+E+L S P D I + + + DG + DI L
Sbjct: 1255 RMKSTEVLPEKTDAVNEALESLESVLRHPADNRTQIRELGQTLIDGGILDDIISEKLEAF 1314
Query: 634 TPEELDDSDF-ETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQ 692
D S E++ + + V E DQ++ Q + + +L ++ + +++ +FQ
Sbjct: 1315 NSRYEDLSHLAESKQISLEKQLQVLRETDQML--QVLQESLGELDKQLTTYLTDRIDAFQ 1372
Query: 693 --EEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIA 750
+E K+ AE+S + + + + R + + S + A
Sbjct: 1373 VPQEAQKIQAEISAHE-----------------LTLEELRRN----MRSQPLTSPESRTA 1411
Query: 751 EAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAE-----VQNLGG 805
GS+MD L R + + Q + QR+ L C + + VKAE V+++
Sbjct: 1412 RGGSQMDVLQRKLREVSTKFQLFQKPANFEQRM-LDCKR--VLDGVKAELHVLDVKDVDP 1468
Query: 806 ELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKAPE 865
+++ + +D M L + + V +K K Q++ ++ S K+ +
Sbjct: 1469 DVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQK-QQTDNPKGMDEQLTSLKVLYND 1527
Query: 866 KKPLVKREKQDETQTKIKRASQ--KKHVNPVQALSEF 900
V KQD ++RASQ +K +LSE+
Sbjct: 1528 LGAQVTEGKQD-----LERASQLARKMKKEAASLSEW 1559
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 41.2 bits (95), Expect = 0.004
Identities = 70/328 (21%), Positives = 127/328 (38%), Gaps = 61/328 (18%)
Query: 536 DGLDRTAGAIRGRAARVIHVVTSEMDNYEP-GVYTEKVLEATKLLSNTVMPRFTEQVEAA 594
D L + A A+ AA ++ S E G+ T+ + AT+ +T Q+ A
Sbjct: 666 DALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALST------SQLVAC 719
Query: 595 VEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRT 654
+ ++ + P+ + + ++A RLV + A +
Sbjct: 720 TKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSA-------------------------S 754
Query: 655 SVQTEDDQLIAGQSARAI-----MAQLPQEQKAKI--AEQVASFQEEKSKLDAEVSKWDD 707
TED QL+ G A A + +L Q KA A + + +
Sbjct: 755 QAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFS 814
Query: 708 SGNDIIVLAKQMCMIMMEMTDFTR-------GKGPLKNTSDVISAAKKIAEAGSRMDKLG 760
S D + +Q ++ +D G+ L+N+ ++SAAK +A+A ++M +
Sbjct: 815 SMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENSRKLLSAAKILADATAKMVEAA 874
Query: 761 RTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQ 820
+ A H PDS +Q QR+ L + + A QN + +V ++
Sbjct: 875 KGAAAH-PDSEEQQ------QRLREAAEGLRMAT--NAAAQNAIKKKLVQRLE------H 919
Query: 821 AAKNLMNAVVQTVKASYVASTKYQKSQG 848
AAK + QT+ A+ A++ + S G
Sbjct: 920 AAKQAAASATQTIAAAQHAASTPKASAG 947
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 40.4 bits (93), Expect = 0.008
Identities = 97/503 (19%), Positives = 192/503 (38%), Gaps = 80/503 (15%)
Query: 288 QIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDL 347
Q D L +E + + EE + I+ + + S DD +R V N V + +Q L
Sbjct: 534 QATPDLLKGQQELTQQTNEETAKQILYN--YLKEGSTDNDDATKRKV---NLVFEKIQTL 588
Query: 348 LSEYMGNA-GRKERSDALNSAID------KMTKKTRDLRRQLRKAVMDHVS--------- 391
S G+A G + ++ + D K+T + +L+RQL+ V + +
Sbjct: 589 KSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMR 648
Query: 392 ----------DSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSIS 441
+ +E N L +E ++ K ++E QV E E+ +L +S
Sbjct: 649 ANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLS 708
Query: 442 NNEEGVKLVRMSASQLE-ALCPQVINA--------------------------ALALAAK 474
+ + + S + + AL +++ A AL A K
Sbjct: 709 EMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALK 768
Query: 475 PQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKD 534
+ + MD KEQ++ +++ L ++V++ T + LA N +D A E
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQ-----AGTEMR 823
Query: 535 VDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAA 594
V L ++GR+ + V E L+ + + + ++ ++
Sbjct: 824 VKLLQEENEKLQGRSEELERRVAQLQRQIED-------LKGDEAKAKETLKKYEGEIRQL 876
Query: 595 VEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSD---FETEDFDVR 651
EAL +E E + A R + + + + + L T E+ S+ E+E +
Sbjct: 877 EEALVH---ARKEEKEAVSARRALENEL-EAAQGNLSQTTQEQKQLSEKLKEESEQKEQL 932
Query: 652 SRTSVQTEDDQLIAGQSARAI---MAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDS 708
R + E+++ G++ + MA + + + E E K K E+++
Sbjct: 933 RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQ 992
Query: 709 GNDIIVLAKQMCMIMMEMTDFTR 731
+ + A++ + M+M D R
Sbjct: 993 LKEKTLEAEKSRLTAMKMQDEMR 1015
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 38.9 bits (89), Expect = 0.022
Identities = 124/707 (17%), Positives = 270/707 (38%), Gaps = 68/707 (9%)
Query: 40 VNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDV-- 97
+ ++S+ ++++ + H A Q + + K+A + L+E++ A ++V
Sbjct: 859 IESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVAR 918
Query: 98 -----RKQGDLMKAAAGEFADDPCSSVKR---------GNMVRAARALLSAVTRLLILAD 143
RK G+ + A+ E +P + R G + +A L A+ R
Sbjct: 919 LETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREA--EQ 976
Query: 144 MADVYKLLVQLKVVEDGILKLRNAGNEQDLG-IQYKALKPEVDKLNIMAAKRQQELKDVG 202
M + + L + G + E+++ + + + + D AA+ + E++
Sbjct: 977 MGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQN 1036
Query: 203 HRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQAT 262
++ LQ+ + T + + ++A + K+L++ + +
Sbjct: 1037 ALNEQRVEFATLQEALAHALTEKEG--KDQELAKLRGLEAAQIKELEELRQTVKQLKEQL 1094
Query: 263 ASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADS 322
A + +H G G + A ++ L + +++ E S +
Sbjct: 1095 AKKE-KEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAE 1153
Query: 323 SCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQL 382
+R +R + + + Q+L A + A + + +K + + Q+
Sbjct: 1154 RASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQV 1213
Query: 383 ----RKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANL-- 436
++A + S LE V +L K G KE+K E + KL E L
Sbjct: 1214 ARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQ 1273
Query: 437 ACSISNN----------EEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDL 486
A + SN+ E V+ +R A + + + + + L A+ +L QE +
Sbjct: 1274 AETASNSARAAERSSALREEVQSLREEAEK-QRVASENLRQELTSQAERAEELGQE-LKA 1331
Query: 487 FKEQWEKQVRVLTDAVDDITSIDDFLA--VSENHILEDVNKCVIALQEKDVDGLDRTAGA 544
++E++ ++ + L+ + TS ++ + H+ + + A +++ + L+++ A
Sbjct: 1332 WQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQA 1391
Query: 545 IRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQ 604
G A ++ E+ P +KV E E + L ++ A
Sbjct: 1392 AGGLRAELLR-AQRELGELIP--LRQKVAEQ----------------ERTAQQLRAEKAS 1432
Query: 605 PMDENEFI-DASRLVYDGIRDIRKAVLMIR--TPEELDDS--DFETEDFDVRSRTSVQTE 659
++ + A L+ + R + + + R ELD + + E VR+ +
Sbjct: 1433 YAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLA 1492
Query: 660 DDQLIAGQSAR--AIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSK 704
+ Q A +AR +M + K K+ E+ FQEE+ KL A+V +
Sbjct: 1493 EVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQ 1539
Score = 35.4 bits (80), Expect = 0.24
Identities = 94/436 (21%), Positives = 182/436 (41%), Gaps = 61/436 (13%)
Query: 477 SKLAQENMDL-FK-EQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVN---KCVIALQ 531
++L++EN DL FK ++ ++ L DA++++T ++ ++ + + + ALQ
Sbjct: 314 NQLSEENGDLSFKLREFASHLQQLQDALNELT--EEHSKATQEWLEKQAQLEKELSAALQ 371
Query: 532 EKDVDGLDRTAGAIRGRAARVIHVVTSEMDN--YEPGVYTEKVLEATKLLSNTV-MPRFT 588
+K L+ ++G+ +++ ++ DN E G VL+ L +
Sbjct: 372 DKKC--LEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANN 429
Query: 589 EQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDF 648
Q++A VE L ++ Q +A L G FE E
Sbjct: 430 TQLQARVEMLETERGQQ-------EAKLLAERG--------------------HFEEEKQ 462
Query: 649 DVRSR-TSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDD 707
+ S T +Q+ L A+ + Q Q A++ QVAS E + L+A + + D
Sbjct: 463 QLSSLITDLQSSISNL---SQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQ 519
Query: 708 SGNDIIVLAK----QMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSR--MDKLGR 761
+ AK Q+ + + ++G L++ + +S++ K E + +K
Sbjct: 520 ELAGLKQQAKEKQAQLAQTLQQQEQASQG---LRHQVEQLSSSLKQKEQQLKEVAEKQEA 576
Query: 762 TIADHCPDSA-CKQDLLAYLQRIALYCHQLNICSKVK-AEVQNLGGELVVSGV--DSAMS 817
T DH A ++ A L+ QL K K A+++ L +L V+ DSA +
Sbjct: 577 TRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQT 636
Query: 818 LI---QAAKNLMNAVVQTVKA--SYVASTKYQKSQGMASLNLPAVSWKMKAPEKKPLVKR 872
+ Q K ++ V+ ++A +++ +A L L S + KA EK+ + +
Sbjct: 637 SVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQE 696
Query: 873 EKQDETQTKIKRASQK 888
+ Q + Q + + S K
Sbjct: 697 KDQLQEQLQALKESLK 712
Score = 35.4 bits (80), Expect = 0.24
Identities = 94/513 (18%), Positives = 207/513 (40%), Gaps = 82/513 (15%)
Query: 61 LAASVEQA-TENFLEKGDKIAKESQFL--KEELVAAVEDVRKQGDLMKAAAGEFADDPCS 117
L A VE TE ++ +A+ F K++L + + D++ + A E + S
Sbjct: 432 LQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEEL--EQAS 489
Query: 118 SVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQY 177
+ +L S +T L D +L + ++ +L +Q+ Q
Sbjct: 490 QAHGARLTAQVASLTSELTTLNATIQQQD-QELAGLKQQAKEKQAQLAQTLQQQEQASQ- 547
Query: 178 KALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAY 237
L+ +V++L+ +++Q+LK+V + + A R + + +A L+ D A
Sbjct: 548 -GLRHQVEQLSSSLKQKEQQLKEVAEKQE--ATRQDHAQQLATAAEEREASLRERDAALK 604
Query: 238 K---------ANRDLIYKQLQ-------QAVTGISNAAQATAS------------DDASQ 269
+ A +++ +QLQ A T ++ A + A + A Q
Sbjct: 605 QLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQ 664
Query: 270 HQGGGGGELAYALNNFDKQIIVDPLSFSEE----RFRPSLEERLESI-----ISGAALMA 320
Q ++A + Q+ + +E+ + + L+E+L+++ ++ +L
Sbjct: 665 EQHEAQAQVA----ELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE 720
Query: 321 DSSCTRD--DRRERIVAECNAVRQAL--------QDLLSEYMGNAGRKERSDALNSAIDK 370
+ D + ++R ++E A ++L ++L E G G + R L A
Sbjct: 721 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEA--- 777
Query: 371 MTKKTRDLRRQLRKAV-MDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANK 429
+T LRR+L +A+ H ++S E V + +++E +Y +F+E
Sbjct: 778 HQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMT 837
Query: 430 LIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDL--- 486
L +E + R + + + + + ++ Q++LA+ + +L
Sbjct: 838 L-------------KEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARA 884
Query: 487 FKEQWEKQVRVLTDAVDDITSIDDFLAVSENHI 519
++ EK+VR DD++++ + +A + +
Sbjct: 885 LQQVQEKEVRA-QKLADDLSTLQEKMAATSKEV 916
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 38.1 bits (87), Expect = 0.037
Identities = 50/236 (21%), Positives = 101/236 (42%), Gaps = 29/236 (12%)
Query: 25 VERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQ 84
V+RLLE L K N+K + KK A +E+ ++ +K + + Q
Sbjct: 758 VDRLLEIL------------KEVENEKNDKDKKI----AELERQVKDQNKKVANLKHKEQ 801
Query: 85 FLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADM 144
K++ +E+ R++ D + ++ + D S K+ + + L ++ +M
Sbjct: 802 VEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKKDDRIEELEEALRESVQITAEREM 858
Query: 145 ADVYKLLVQL---KVVEDGILKLRNAGNEQD-----LGIQYKALKPEVDKLNIMAAKRQQ 196
+ + K VE+ ++ + E + L ++L + L + A+R++
Sbjct: 859 VLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRK 918
Query: 197 ELKDVGHRDQMAAARGILQK--NVPILYTASQACLQHPDVAAYKANRDLIYKQLQQ 250
L++V Q A I +K N+ +L +S +VAA K +D + +QL+Q
Sbjct: 919 HLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 974
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 38.1 bits (87), Expect = 0.037
Identities = 50/236 (21%), Positives = 101/236 (42%), Gaps = 29/236 (12%)
Query: 25 VERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQ 84
V+RLLE L K N+K + KK A +E+ ++ +K + + Q
Sbjct: 730 VDRLLEIL------------KEVENEKNDKDKKI----AELERQVKDQNKKVANLKHKEQ 773
Query: 85 FLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADM 144
K++ +E+ R++ D + ++ + D S K+ + + L ++ +M
Sbjct: 774 VEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKKDDRIEELEEALRESVQITAEREM 830
Query: 145 ADVYKLLVQL---KVVEDGILKLRNAGNEQD-----LGIQYKALKPEVDKLNIMAAKRQQ 196
+ + K VE+ ++ + E + L ++L + L + A+R++
Sbjct: 831 VLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRK 890
Query: 197 ELKDVGHRDQMAAARGILQK--NVPILYTASQACLQHPDVAAYKANRDLIYKQLQQ 250
L++V Q A I +K N+ +L +S +VAA K +D + +QL+Q
Sbjct: 891 HLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 946
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 37.7 bits (86), Expect = 0.049
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 23/157 (14%)
Query: 571 KVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDAS----------RLVYD 620
KV E K L ++ E + + S+P + +D N + R +
Sbjct: 416 KVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIAR 475
Query: 621 GIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQ 680
+ I+K + +T ++L D+D E +D D T+ + E++ L+ ++ P+++
Sbjct: 476 DVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNT-------PKQK 528
Query: 681 KAKIAEQVAS-----FQEEKSKLDAEV-SKWDDSGND 711
+ KI +Q S +EEKS+ E SK D G +
Sbjct: 529 EKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEE 565
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 37.7 bits (86), Expect = 0.049
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 23/157 (14%)
Query: 571 KVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDAS----------RLVYD 620
KV E K L ++ E + + S+P + +D N + R +
Sbjct: 416 KVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIAR 475
Query: 621 GIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQ 680
+ I+K + +T ++L D+D E +D D T+ + E++ L+ ++ P+++
Sbjct: 476 DVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNT-------PKQK 528
Query: 681 KAKIAEQVAS-----FQEEKSKLDAEV-SKWDDSGND 711
+ KI +Q S +EEKS+ E SK D G +
Sbjct: 529 EKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEE 565
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 37.7 bits (86), Expect = 0.049
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 23/157 (14%)
Query: 571 KVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDAS----------RLVYD 620
KV E K L ++ E + + S+P + +D N + R +
Sbjct: 416 KVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIAR 475
Query: 621 GIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQ 680
+ I+K + +T ++L D+D E +D D T+ + E++ L+ ++ P+++
Sbjct: 476 DVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNT-------PKQK 528
Query: 681 KAKIAEQVAS-----FQEEKSKLDAEV-SKWDDSGND 711
+ KI +Q S +EEKS+ E SK D G +
Sbjct: 529 EKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEE 565
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 37.0 bits (84), Expect = 0.083
Identities = 139/675 (20%), Positives = 262/675 (38%), Gaps = 120/675 (17%)
Query: 25 VERLLEPLVTQVTTLVNTNSKGPSNKKRG---RSKKAHVLAASVEQATENFLEKGDKIAK 81
+ R+ L+ + N+N K K+R R+ K ++ + +EQ EN K+A
Sbjct: 620 LSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNL--SELEQLNENL----KKVAF 673
Query: 82 ESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLIL 141
+ + E+LV A EDVR Q + A + S+++ +V + + L
Sbjct: 674 DVKMENEKLVLACEDVRHQLEECLAGNNQL------SLEKNTIVETLKMEKGEIEAELCW 727
Query: 142 ADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYK-----ALKPEVDKLNIMAAKRQQ 196
A +LL + E I +L NA N +Q + L + D + I K+
Sbjct: 728 AKK----RLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKD-MEIAELKKNI 782
Query: 197 ELKDVGHRDQMAAARGIL--QKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTG 254
E D H++ L QK + L + ++ + K +L + QA+
Sbjct: 783 EQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEEL--DKYSQALRK 840
Query: 255 ISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEER-LESII 313
Q D S G + N+ +++ + L + R P + + L+S+
Sbjct: 841 NEILRQTIEEKDRSL------GSMKEENNHLQEEL--ERLREEQSRTAPVADPKTLDSVT 892
Query: 314 SGAALMADSSCTRDDRRE------RIVAECNAVR----QALQDLLSEYMGNAGRKERSDA 363
A+ ++ + ++ E +I+ + N + Q+LQ+ E + E+ +A
Sbjct: 893 ELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNA 952
Query: 364 LNS--------AIDKMTKKTRDLRRQL---RKAVMDHVSDSFLETNVPLLVLIEAAKNGN 412
++ I + K ++ QL R+ + SD F ET V L + +NG+
Sbjct: 953 THTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNI----ENGS 1008
Query: 413 EKEVKEYAQV--------FREHANKLIEVANLACS-----ISNNEEGVKLVRMSASQLEA 459
EK A+ RE KL+ N++ + +S +E G + LE
Sbjct: 1009 EKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEI 1068
Query: 460 LCPQVINAALALAAKPQSKL-AQENMDLFKEQWEKQVRVLTDAVDDITSID-------DF 511
Q ++A ++ + Q + Q+ + + + EK VL + + + + D
Sbjct: 1069 ---QALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDI 1125
Query: 512 LAVSENHI--LEDVNKCVIA--------------------LQEKDVDGLDRTAGAIRGRA 549
+A E + L+D NK + ++EKD++ A+ +
Sbjct: 1126 VAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIE-----IDALSQKC 1180
Query: 550 ARVIHVV-TSEMDNYEPGVYT---EKVLEATKLLSNTV--MPRFTEQVEAAVEALSSDPA 603
++ V+ TS N GV + E++L+ L V M + +QV V+ + + A
Sbjct: 1181 QTLLAVLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESA 1240
Query: 604 QPMDENEFIDASRLV 618
Q +E + A LV
Sbjct: 1241 QLQEELHQLQAQVLV 1255
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 37.0 bits (84), Expect = 0.083
Identities = 80/463 (17%), Positives = 182/463 (39%), Gaps = 42/463 (9%)
Query: 286 DKQIIVDPLSFSEERFRPS------------LEERLESIISGAALMADSSCTRDDR---R 330
DK P +S+E F+ S LE++L ++ A+ ++S T
Sbjct: 151 DKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDE 210
Query: 331 ERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAV---- 386
+R+++ + LQ ++ RKE + T LRR L++ +
Sbjct: 211 DRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKIEVVR 270
Query: 387 -MDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVAN-LACSISNNE 444
+ V S T L E + E E++E A + N++ ++++ L + E
Sbjct: 271 KLSEVERSLSNTEDECTHLKEMNERTQE-ELRELANKYNGAVNEIKDLSDKLKVAEGKQE 329
Query: 445 EGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEK-QVRVLTDAVD 503
E + + +L+ ++ L AK ++ Q + D E+ Q +L+ +
Sbjct: 330 EIQQKGQAEKKELQHKIDEMEEKEQELQAKIEA--LQADNDFTNERLTALQEHLLSKSGG 387
Query: 504 DITSIDDFLA-----VSENHILEDVNKCVIALQE----KDVDGLDRTAGAIRGRAARVIH 554
D T I F+ + E H+ + V + ++ + K+ D D + + +
Sbjct: 388 DCTFIHQFIECQKKLIVEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDTTD 447
Query: 555 VVTSEMDNYEPGVYTEKVLE-----ATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDEN 609
E D EP + + +++ + + +++ A E + + +
Sbjct: 448 AQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQ 507
Query: 610 EFIDASRLVY-DGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQS 668
++ R Y + + + K + +++ +L +TE+ + + + D+L++ +
Sbjct: 508 ALLEEERKAYRNQVEESTKQIQVLQA--QLQRLHIDTENLREEKDSEITSTRDELLSARD 565
Query: 669 ARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGND 711
++ Q + ++ +AS QEE K+ AE+ +W + ++
Sbjct: 566 EILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASE 608
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 36.2 bits (82), Expect = 0.14
Identities = 44/208 (21%), Positives = 87/208 (41%), Gaps = 22/208 (10%)
Query: 372 TKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLI 431
T +T++ + Q+ + ++ S S + N LL+ + +N NE +KE RE L
Sbjct: 1099 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE-----REDLKSLY 1153
Query: 432 EVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQW 491
+ I ++E+ L AS+ E+L ++ K A +N+++
Sbjct: 1154 D-----SLIKDHEKLELLHERQASEYESL----------ISKHGTLKSAHKNLEVEHRDL 1198
Query: 492 EKQVRVLTDAVDDITSIDDFLAV-SENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAA 550
E + L + ++ L V E +LE+ N +A + K + G + +
Sbjct: 1199 EDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1258
Query: 551 RVIHVVTSEMDNYEPGVYTEKVLEATKL 578
+ V+ ++ N + + K LE T+L
Sbjct: 1259 KETEVLQTDHKNLKSLLNNSK-LEQTRL 1285
Score = 33.5 bits (75), Expect = 0.92
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 14/180 (7%)
Query: 17 SLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATE--NFLE 74
+L+ + LA++R L Q TTL N+K S+ ++ + + + +
Sbjct: 1078 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1137
Query: 75 KGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSA 134
+ + + KE + LK + ++D K L + A E+ S + + +++A L
Sbjct: 1138 ENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYE----SLISKHGTLKSAHKNLEV 1193
Query: 135 VTRLL------ILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLN 188
R L +L + L LKV ++ +L L N N + + +YK L E D+LN
Sbjct: 1194 EHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKML-LENK-NHETVAAEYKKLCGENDRLN 1251
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 36.2 bits (82), Expect = 0.14
Identities = 44/208 (21%), Positives = 87/208 (41%), Gaps = 22/208 (10%)
Query: 372 TKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLI 431
T +T++ + Q+ + ++ S S + N LL+ + +N NE +KE RE L
Sbjct: 1098 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE-----REDLKSLY 1152
Query: 432 EVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQW 491
+ I ++E+ L AS+ E+L ++ K A +N+++
Sbjct: 1153 D-----SLIKDHEKLELLHERQASEYESL----------ISKHGTLKSAHKNLEVEHRDL 1197
Query: 492 EKQVRVLTDAVDDITSIDDFLAV-SENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAA 550
E + L + ++ L V E +LE+ N +A + K + G + +
Sbjct: 1198 EDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1257
Query: 551 RVIHVVTSEMDNYEPGVYTEKVLEATKL 578
+ V+ ++ N + + K LE T+L
Sbjct: 1258 KETEVLQTDHKNLKSLLNNSK-LEQTRL 1284
Score = 33.5 bits (75), Expect = 0.92
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 14/180 (7%)
Query: 17 SLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATE--NFLE 74
+L+ + LA++R L Q TTL N+K S+ ++ + + + +
Sbjct: 1077 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1136
Query: 75 KGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSA 134
+ + + KE + LK + ++D K L + A E+ S + + +++A L
Sbjct: 1137 ENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYE----SLISKHGTLKSAHKNLEV 1192
Query: 135 VTRLL------ILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLN 188
R L +L + L LKV ++ +L L N N + + +YK L E D+LN
Sbjct: 1193 EHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKML-LENK-NHETVAAEYKKLCGENDRLN 1250
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 36.2 bits (82), Expect = 0.14
Identities = 126/716 (17%), Positives = 263/716 (36%), Gaps = 119/716 (16%)
Query: 276 GELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVA 335
GE+ LN DK++ L+E L+S ++ A S + D R+R++
Sbjct: 2160 GEIQVTLNKKDKEV-------------QQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2206
Query: 336 ECNAVRQALQDLLSEYMGNAGRKE-RSDALNSAIDKMTKKTRDLRRQLRKAVMD-HVSDS 393
E + D + KE L + +M+ +L+ + + D + +S
Sbjct: 2207 EAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2266
Query: 394 FLETNVPLLVLIEAAKNGNEKE----VKEYAQVFREHANKLIEV---------------- 433
+T V L + G KE ++E ++ N+L ++
Sbjct: 2267 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN 2326
Query: 434 ---------ANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENM 484
NL I E ++ + S QLE + A+ L ++ ++ +
Sbjct: 2327 SLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLET----DLQASRELTSRLHEEINMKEQ 2382
Query: 485 DLF------KEQWEKQVRVLTDAVD-DITSIDDFLA--VSENHILEDVNKCVI------- 528
+ +E + + L D +I +++ L+ EN +LE+ NK +
Sbjct: 2383 KIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2442
Query: 529 ----------ALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKL 578
Q+ +D ++ +++ R++ + E + +LE +L
Sbjct: 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIV----GDYQQLEER-HLSIILEKDQL 2497
Query: 579 LSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEEL 638
+ +++ + L S EN +DA + Y R+ V+ I+ ++
Sbjct: 2498 IQEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQY---REDLNQVITIKDSQQK 2552
Query: 639 DDSDFETEDFDVRSRTSVQTED---DQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEK 695
+ + + + E+ + A + R L QE+K +++++ S +
Sbjct: 2553 QLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNAL-QEEKQDLSKEIESLKVSI 2611
Query: 696 SKLDAEVSKWDDSGN------DIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVI--SAAK 747
S+L +V+ + G + V +++ + + + L+ + AAK
Sbjct: 2612 SQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAK 2671
Query: 748 KIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSK--VKAEVQNLGG 805
K+ E ++ K + + H + + +R+A L + + +N G
Sbjct: 2672 KVGEIEDKLKKELKHL--HHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGL 2729
Query: 806 ELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTK---YQKSQGMASLN----LPAVS 858
+ +MS +Q +++ N + +K Y AS K K QG+ + L +
Sbjct: 2730 TAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETA 2789
Query: 859 WKMKAPEKKPLVKREKQDETQTKIKRASQKKHV--------NPVQALSEFKAMDSI 906
+ M + E+ L EK + Q + + Q H+ N VQ+ S KAM S+
Sbjct: 2790 FSMNSTEENSLSHLEKLN--QQLLSKDEQLLHLSSQLEDSYNQVQSFS--KAMASL 2841
Score = 30.8 bits (68), Expect = 6.0
Identities = 58/304 (19%), Positives = 118/304 (38%), Gaps = 37/304 (12%)
Query: 171 QDLGIQYKALKPEVDKLNIMAAKRQQELKD-VGHRDQMAAARGILQKNVPILYTA-SQAC 228
+++G + +A + KL R++ LK+ +++++ ARG +++ L SQ
Sbjct: 1469 EEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS 1528
Query: 229 LQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNF--D 286
Q+ + L+ ++ + +T + + S +S L AL D
Sbjct: 1529 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCES------LKLALEGLTED 1582
Query: 287 KQIIVDPL-SFSEERFRPSLE--ERLESIISGAALMADSSCTRDDRRERIVAECNAVRQA 343
K+ +V + S + S E E+ + + ++ S + ERI AVRQ
Sbjct: 1583 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1642
Query: 344 LQDLLSEYMG-NAGRKERSDALNSA---IDKMTKKTRDLRRQLRKAVMD----------- 388
Q+L + A +KE L A +++M +K R + ++ +++
Sbjct: 1643 KQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1702
Query: 389 ---------HVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACS 439
++ L +N + +E K E K++ + E + EV +L
Sbjct: 1703 VHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ 1762
Query: 440 ISNN 443
I N
Sbjct: 1763 IEGN 1766
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 35.8 bits (81), Expect = 0.19
Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 52/225 (23%)
Query: 291 VDPLSFSEERFRPSLE--ERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLL 348
VD + +E+ R L+ E+L+S++ A+ + D + R E L+ L
Sbjct: 382 VDQVVREKEKLRSDLDKAEKLKSLM--ASEVDDHHAAIERRNE----------YNLRKLD 429
Query: 349 SEY------MGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLL 402
EY + N RKER L A K+ +L +++ KA + ++++ + L
Sbjct: 430 EEYKERIAALKNELRKEREQILQQA----GKQRLELEQEIEKAKTE---ENYIRDRLALS 482
Query: 403 VLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCP 462
+ KE E+A KL E NL + N E V A + L P
Sbjct: 483 L----------KENSRLENELLENAEKLAEYENLTNKLQRNLENVL-----AEKFGDLDP 527
Query: 463 QVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITS 507
+ + L +E + + ++E+Q RVL D VD++ S
Sbjct: 528 ----------SSAEFFLQEERLTQMRNEYERQCRVLQDQVDELQS 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,129,300
Number of Sequences: 37866
Number of extensions: 1106952
Number of successful extensions: 3778
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 3630
Number of HSP's gapped (non-prelim): 230
length of query: 906
length of database: 18,247,518
effective HSP length: 111
effective length of query: 795
effective length of database: 14,044,392
effective search space: 11165291640
effective search space used: 11165291640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.