Search of human proteins with 55749758

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo
sapiens]
         (1576 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sap...  3153   0.0  
gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sap...  2347   0.0  
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]    2303   0.0  
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]   2292   0.0  
gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]   1522   0.0  
gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]    1153   0.0  
gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]    1088   0.0  
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]   1055   0.0  
gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]    1030   0.0  
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    44   0.001
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]         43   0.002
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]         43   0.002
gi|66730481 neuregulin 3 [Homo sapiens]                                42   0.004
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]      42   0.005
gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]              40   0.023
gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]              40   0.023
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         39   0.030
gi|151301154 mucin 6, gastric [Homo sapiens]                           39   0.040
gi|161016767 mucin 21 [Homo sapiens]                                   39   0.040
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        39   0.052
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        39   0.052
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    38   0.068
gi|55742730 storkhead box 2 [Homo sapiens]                             38   0.068
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    38   0.088
gi|38202211 N-acetylglucosamine-1-phosphate transferase [Homo sa...    38   0.088
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot...    37   0.12 
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot...    37   0.12 
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora...    37   0.12 
gi|150170670 piccolo isoform 2 [Homo sapiens]                          37   0.12 
gi|150378539 piccolo isoform 1 [Homo sapiens]                          37   0.12 

>gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sapiens]
          Length = 1576

 Score = 3154 bits (8176), Expect = 0.0
 Identities = 1576/1576 (100%), Positives = 1576/1576 (100%)

Query: 1    MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
            MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD
Sbjct: 1    MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60

Query: 61   SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
            SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA
Sbjct: 61   SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120

Query: 121  LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
            LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ
Sbjct: 121  LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180

Query: 181  GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI 240
            GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI
Sbjct: 181  GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI 240

Query: 241  DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS 300
            DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS
Sbjct: 241  DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS 300

Query: 301  EEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD 360
            EEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD
Sbjct: 301  EEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD 360

Query: 361  MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFY 420
            MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFY
Sbjct: 361  MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFY 420

Query: 421  GCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIVQFK 480
            GCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIVQFK
Sbjct: 421  GCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIVQFK 480

Query: 481  GWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC 540
            GWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC
Sbjct: 481  GWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC 540

Query: 541  QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRV 600
            QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRV
Sbjct: 541  QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRV 600

Query: 601  HAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSH 660
            HAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSH
Sbjct: 601  HAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSH 660

Query: 661  GLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV 720
            GLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV
Sbjct: 661  GLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV 720

Query: 721  QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVN 780
            QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVN
Sbjct: 721  QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVN 780

Query: 781  SAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKT 840
            SAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKT
Sbjct: 781  SAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKT 840

Query: 841  VYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 900
            VYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP
Sbjct: 841  VYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 900

Query: 901  ANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASVMVG 960
            ANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASVMVG
Sbjct: 901  ANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASVMVG 960

Query: 961  NLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTTVCT 1020
            NLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTTVCT
Sbjct: 961  NLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTTVCT 1020

Query: 1021 ASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPH 1080
            ASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPH
Sbjct: 1021 ASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPH 1080

Query: 1081 AQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKR 1140
            AQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKR
Sbjct: 1081 AQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKR 1140

Query: 1141 LPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQIAICLD 1200
            LPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQIAICLD
Sbjct: 1141 LPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQIAICLD 1200

Query: 1201 PYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTK 1260
            PYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTK
Sbjct: 1201 PYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTK 1260

Query: 1261 GLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRV 1320
            GLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRV
Sbjct: 1261 GLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRV 1320

Query: 1321 NVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE 1380
            NVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE
Sbjct: 1321 NVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE 1380

Query: 1381 TKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGF 1440
            TKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGF
Sbjct: 1381 TKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGF 1440

Query: 1441 VRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTN 1500
            VRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTN
Sbjct: 1441 VRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTN 1500

Query: 1501 LLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRD 1560
            LLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRD
Sbjct: 1501 LLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRD 1560

Query: 1561 SFLADQLDPIYVAYNM 1576
            SFLADQLDPIYVAYNM
Sbjct: 1561 SFLADQLDPIYVAYNM 1576


>gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sapiens]
          Length = 1556

 Score = 2347 bits (6082), Expect = 0.0
 Identities = 1145/1576 (72%), Positives = 1331/1576 (84%), Gaps = 20/1576 (1%)

Query: 1    MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
            MA+R LE       ALP EVRA+LAELELELSEGDITQKGYEKKRSKL+  Y PQ    D
Sbjct: 1    MADRSLEGM-----ALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVD 55

Query: 61   SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
             A+ +E R     PS+A     S+YHR RS G+RDERYRSD+HTEAVQAALAKHKE+KMA
Sbjct: 56   QALPQE-RRAPVTPSSA-----SRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMA 109

Query: 121  LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
            +PMP+KRRS  VQ+  DA TPPDTSS SEDEGS++  +  +    Q   N E WI+++I 
Sbjct: 110  VPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIH 169

Query: 181  GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI 240
            GS+TS+++SS+   G   G +  LADV A T IEN SAPPDVTT TS  S         +
Sbjct: 170  GSTTSTTSSSSTQSGG-SGAAHRLADVMAQTHIENHSAPPDVTTYTSEHS-------IQV 221

Query: 241  DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS 300
            + P              + LM+T DGVPVSSRVS KIQQL+NTLKRPKRPPL+EFFVDD 
Sbjct: 222  ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281

Query: 301  EEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD 360
            EE++EV QPDPNQPKPEG QM  ++GE LGV+ NWPP+LE+ALQRWGT   K  CLT +D
Sbjct: 282  EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341

Query: 361  MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFY 420
              GKP+Y LTYGKLW+RS+K+AY++L+KLGTK EP+++PGDRVALV+PNNDP  FM AFY
Sbjct: 342  TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401

Query: 421  GCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIVQFK 480
            GCLLAEV+PVPIEVPLTRKDAG QQIGFLLGSCG+ +ALTS+ C KGLPK+  GEI QFK
Sbjct: 402  GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461

Query: 481  GWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC 540
            GWP+L W VT+SK+LSKPP+DW PHI  A  + AYIEYKT K+GSV+GVTV+R A+L+HC
Sbjct: 462  GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521

Query: 541  QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRV 600
            QAL+QAC Y+E ETIVNVLDFKKD GLWHG+  +VMN MH IS+PYS+MK  PLSW+Q+V
Sbjct: 522  QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581

Query: 601  HAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSH 660
              +KAKVA VK RD+HWA++AHRDQRD++LSSLRMLIV DGANPWS+SSCDAFL++FQS 
Sbjct: 582  CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641

Query: 661  GLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV 720
            GL+ E ICPCA+S EA+TVAIRRP       PGR +LSM+GL+YGVIRV++E+K S LTV
Sbjct: 642  GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701

Query: 721  QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVN 780
            QDVG VMPG +MC VKPDG PQLC+TDEIGE+CV +   G  Y+GL+G+TKNTFEV P+ 
Sbjct: 702  QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761

Query: 781  SAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKT 840
            S+G+P+ + PFIR+GLLGFVGPG LVFVVGKMDGL++VSGRRHNADDIVAT LAVE +K 
Sbjct: 762  SSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKF 821

Query: 841  VYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 900
            VYRGRIAVFSV+V +DERIV+VAEQRPD++EEDSFQWMSRVLQAIDSIHQVGVYCLALVP
Sbjct: 822  VYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 881

Query: 901  ANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASVMVG 960
            ANTLPKTPLGGIH+S+TKQLFLEGSLHPCN+LMCPHTCVTNLPKPRQKQP +GPASVMVG
Sbjct: 882  ANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVG 941

Query: 961  NLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTTVCT 1020
            NLV+GKRIAQA+GRDLGQIE+ND  RK  FL+E+LQWRAQ TPDH+L+ LLN +G    +
Sbjct: 942  NLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANS 1001

Query: 1021 ASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPH 1080
             +C+QLHKRAE+IA +L ++GHL  GD+V L+YPPGI+LIAAFYGCLYAGC+P+TVRPPH
Sbjct: 1002 LTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPH 1061

Query: 1081 AQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKR 1140
             QN+  TLPTV+MIV+VS++AC++T+Q + +LLRSREAAAAVDV+TWP I+DTDDLP+KR
Sbjct: 1062 PQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKR 1121

Query: 1141 LPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQIAICLD 1200
              Q+ KP  P+ LAYLDFSVSTTGML GVKMSH+A +A CR+IKLQCELY SR++AICLD
Sbjct: 1122 PAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLD 1181

Query: 1201 PYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTK 1260
            PYCGLGF LWCLCSVYSGHQS+LIPP ELE N  LWL  V+QYK+RDTFCSYSVMELCTK
Sbjct: 1182 PYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTK 1241

Query: 1261 GLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRV 1320
            GLG+Q E LK RG++LS VRTCVVVAEERPR+AL QSFSKLFKD+GL PRAVST+FG RV
Sbjct: 1242 GLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRV 1301

Query: 1321 NVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE 1380
            N+AICLQGTSGPDPTTVYVD+++LRHDRVRLVERG+P SL L ESGKILPGV+++I NPE
Sbjct: 1302 NLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE 1361

Query: 1381 TKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGF 1440
            TKGP+GDSHLGEIWV+S H ASGY+TIY  E+LQ+DHFN+RLSFGD  QT+WARTGYLGF
Sbjct: 1362 TKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGD-TQTIWARTGYLGF 1420

Query: 1441 VRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTN 1500
            +RRTELT A GERHDALYVVGALDE +ELRG+RYHPIDIETSV R H+S+ ECAVFTWTN
Sbjct: 1421 LRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTN 1480

Query: 1501 LLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRD 1560
            LLVVVVEL GSEQEALDLVPLVTNVVLEEHYLIVGVVVVVD GVIPINSRGEKQRMHLRD
Sbjct: 1481 LLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRD 1540

Query: 1561 SFLADQLDPIYVAYNM 1576
             FLADQLDPIYVAYNM
Sbjct: 1541 GFLADQLDPIYVAYNM 1556


>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
          Length = 1571

 Score = 2303 bits (5969), Expect = 0.0
 Identities = 1132/1589 (71%), Positives = 1328/1589 (83%), Gaps = 31/1589 (1%)

Query: 1    MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
            MA+RG    P   A LP EVR  LAELELELSEGDITQKGYEKKR+KLL+ Y P  Q  D
Sbjct: 1    MADRGC---PLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID 57

Query: 61   SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
             ++Q E  N+ P PS    +AP K  ++R   +RDER+RSD+HTEAVQAALAK+KE+KM 
Sbjct: 58   PSLQAE--NRIPGPSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM- 113

Query: 121  LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
             PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L++   QS  + E W++R IQ
Sbjct: 114  -PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172

Query: 181  GSSTSSSASSTLSHGEVKGTSG-------------SLADVFANTRIENFSAPPDVTTTTS 227
            GSSTSSSASST SH   + T+              +LA + A+T I+  SAPPDVTT   
Sbjct: 173  GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT--- 229

Query: 228  SSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRP 287
                   +  +  + P    V+ + +G +  S+++TADGVPV+SRVS+KIQQLLNTLKRP
Sbjct: 230  -----GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGVPVNSRVSSKIQQLLNTLKRP 283

Query: 288  KRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWG 347
            KRPPLKEFFVDD EE++EV QPDPNQPKPEG + + ++GEPL      PP+L + LQRWG
Sbjct: 284  KRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWG 343

Query: 348  TTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVY 407
            TTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLNKL +KNEP+LKPGDRVALV+
Sbjct: 344  TTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVF 403

Query: 408  PNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKG 467
            PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+GFLLGSCG+ LALT++ C KG
Sbjct: 404  PNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKG 463

Query: 468  LPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVM 527
            LPK Q GE+  FKGWP L W+V D K+L+KPPKDW P     GT  AYIEYKTSKEGS +
Sbjct: 464  LPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523

Query: 528  GVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYS 587
            GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGLWHG+  +VMN+MH +SVPY+
Sbjct: 524  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583

Query: 588  VMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSV 647
            +MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRDVSLSSLRMLIV DGANPWS+
Sbjct: 584  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSI 643

Query: 648  SSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVI 707
            SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   G P P +A+LSMNGLSYGVI
Sbjct: 644  SSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVI 703

Query: 708  RVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLA 767
            RV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTDE+GEICVSS   G  Y+GL 
Sbjct: 704  RVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLL 763

Query: 768  GVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADD 827
            G+TKN FE +PV + G+P+ D PF R+GLLGF+GP +LVF+VGK+DGL++   RRHNADD
Sbjct: 764  GITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADD 823

Query: 828  IVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDS 887
            +VAT LAVE +K VYRGRIAVFSV+V +D+RIV+VAEQRPDASEEDSFQWMSRVLQAIDS
Sbjct: 824  VVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDS 883

Query: 888  IHQVGVYCLALVPANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQ 947
            IHQVGVYCLALVPANTLPK PLGGIHIS+TKQ FLEG+LHPCN+LMCPHTCVTNLPKPRQ
Sbjct: 884  IHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQ 943

Query: 948  KQPGVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVL 1007
            KQP VGPAS++VGNLVAGKRIAQA+GR+L  +E++D  RK  FLA++LQWRA  TPDH L
Sbjct: 944  KQPEVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPL 1003

Query: 1008 FMLLNAKGTTVCTASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCL 1067
            F+LLNAKGT   TA+C+QLHKRAER+A+ L +KG L+ GD+V L+YPPG++LIAAFYGCL
Sbjct: 1004 FLLLNAKGTVTSTATCVQLHKRAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCL 1063

Query: 1068 YAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTW 1127
            Y GC+PVTVRPPH QNL  TLPTV+MIV+VSK+AC+LT+Q + RLLRS+EAAAAVD++TW
Sbjct: 1064 YCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTW 1123

Query: 1128 PTIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQC 1187
            PTI+DTDD+P+K++  +++PP+P++LAYLDFSVSTTG+L GVKMSH+A +ALCR+IKLQC
Sbjct: 1124 PTILDTDDIPKKKIASVFRPPSPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQC 1183

Query: 1188 ELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRD 1247
            ELY SRQIAICLDPYCGLGFALWCLCSVYSGHQSVL+PP+ELE+N+ LWLS V+QYK R 
Sbjct: 1184 ELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARV 1243

Query: 1248 TFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGL 1307
            TFCSYSVME+CTKGLG Q  VL+ +G+NLSCVRTC+VVAEERPR+AL QSFSKLFKD+GL
Sbjct: 1244 TFCSYSVMEMCTKGLGAQTGVLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGL 1303

Query: 1308 SPRAVSTTFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGK 1367
              RAVSTTFG RVNVAICLQGT+GPDPTTVYVD+++LRHDRVRLVERG+P SL L ESGK
Sbjct: 1304 PARAVSTTFGCRVNVAICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGK 1363

Query: 1368 ILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDA 1427
            ILPGVKV+I + ETKGP+GDSHLGEIWV+SPH A+GYYT+Y  E L ADHF+ RLSFGD 
Sbjct: 1364 ILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFSARLSFGD- 1422

Query: 1428 AQTLWARTGYLGFVRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIH 1487
             QT+WARTGYLGF+RRTELT A+G RHDALYVVG+LDETLELRG+RYHPIDIETSV R H
Sbjct: 1423 TQTIWARTGYLGFLRRTELTDASGGRHDALYVVGSLDETLELRGMRYHPIDIETSVIRAH 1482

Query: 1488 RSIAECAVFTWTNLLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPI 1547
            RSIAECAVFTWTNLLVVVVEL G EQ+ALDLV LVTNVVLEEHYL+VGVVV+VDPGVIPI
Sbjct: 1483 RSIAECAVFTWTNLLVVVVELDGLEQDALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPI 1542

Query: 1548 NSRGEKQRMHLRDSFLADQLDPIYVAYNM 1576
            NSRGEKQRMHLRD FLADQLDPIYVAYNM
Sbjct: 1543 NSRGEKQRMHLRDGFLADQLDPIYVAYNM 1571


>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
          Length = 1567

 Score = 2292 bits (5939), Expect = 0.0
 Identities = 1129/1589 (71%), Positives = 1325/1589 (83%), Gaps = 35/1589 (2%)

Query: 1    MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
            MA+RG    P   A LP EVR  LAELELELSEGDITQKGYEKKR+KLL+ Y P  Q  D
Sbjct: 1    MADRGC---PLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID 57

Query: 61   SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
             ++Q E  N+ P PS    +AP K  ++R   +RDER+RSD+HTEAVQAALAK+KE+KM 
Sbjct: 58   PSLQAE--NRIPGPSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM- 113

Query: 121  LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
             PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L++   QS  + E W++R IQ
Sbjct: 114  -PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172

Query: 181  GSSTSSSASSTLSHGEVKGTSG-------------SLADVFANTRIENFSAPPDVTTTTS 227
            GSSTSSSASST SH   + T+              +LA + A+T I+  SAPPDVTT   
Sbjct: 173  GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT--- 229

Query: 228  SSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRP 287
                   +  +  + P    V+ + +G +  S+++TADGVPV+SRVS+KIQQLLNTLKRP
Sbjct: 230  -----GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGVPVNSRVSSKIQQLLNTLKRP 283

Query: 288  KRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWG 347
            KRPPLKEFFVDD EE++E    DPNQPKPEG + + ++GEPL      PP+L + LQRWG
Sbjct: 284  KRPPLKEFFVDDFEELLE----DPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWG 339

Query: 348  TTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVY 407
            TTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLNKL +KNEP+LKPGDRVALV+
Sbjct: 340  TTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVF 399

Query: 408  PNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKG 467
            PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+GFLLGSCG+ LALT++ C KG
Sbjct: 400  PNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKG 459

Query: 468  LPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVM 527
            LPK Q GE+  FKGWP L W+V D K+L+KPPKDW P     GT  AYIEYKTSKEGS +
Sbjct: 460  LPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 519

Query: 528  GVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYS 587
            GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGLWHG+  +VMN+MH +SVPY+
Sbjct: 520  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 579

Query: 588  VMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSV 647
            +MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRDVSLSSLRMLIV DGANPWS+
Sbjct: 580  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSI 639

Query: 648  SSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVI 707
            SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   G P P +A+LSMNGLSYGVI
Sbjct: 640  SSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVI 699

Query: 708  RVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLA 767
            RV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTDE+GEICVSS   G  Y+GL 
Sbjct: 700  RVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLL 759

Query: 768  GVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADD 827
            G+TKN FE +PV + G+P+ D PF R+GLLGF+GP +LVF+VGK+DGL++   RRHNADD
Sbjct: 760  GITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADD 819

Query: 828  IVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDS 887
            +VAT LAVE +K VYRGRIAVFSV+V +D+RIV+VAEQRPDASEEDSFQWMSRVLQAIDS
Sbjct: 820  VVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDS 879

Query: 888  IHQVGVYCLALVPANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQ 947
            IHQVGVYCLALVPANTLPK PLGGIHIS+TKQ FLEG+LHPCN+LMCPHTCVTNLPKPRQ
Sbjct: 880  IHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQ 939

Query: 948  KQPGVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVL 1007
            KQP VGPAS++VGNLVAGKRIAQA+GR+L  +E++D  RK  FLA++LQWRA  TPDH L
Sbjct: 940  KQPEVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPL 999

Query: 1008 FMLLNAKGTTVCTASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCL 1067
            F+LLNAKGT   TA+C+QLHKRAER+A+ L +KG L+ GD+V L+YPPG++LIAAFYGCL
Sbjct: 1000 FLLLNAKGTVTSTATCVQLHKRAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCL 1059

Query: 1068 YAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTW 1127
            Y GC+PVTVRPPH QNL  TLPTV+MIV+VSK+AC+LT+Q + RLLRS+EAAAAVD++TW
Sbjct: 1060 YCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTW 1119

Query: 1128 PTIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQC 1187
            PTI+DTDD+P+K++  +++PP+P++LAYLDFSVSTTG+L GVKMSH+A +ALCR+IKLQC
Sbjct: 1120 PTILDTDDIPKKKIASVFRPPSPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQC 1179

Query: 1188 ELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRD 1247
            ELY SRQIAICLDPYCGLGFALWCLCSVYSGHQSVL+PP+ELE+N+ LWLS V+QYK R 
Sbjct: 1180 ELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARV 1239

Query: 1248 TFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGL 1307
            TFCSYSVME+CTKGLG Q  VL+ +G+NLSCVRTC+VVAEERPR+AL QSFSKLFKD+GL
Sbjct: 1240 TFCSYSVMEMCTKGLGAQTGVLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGL 1299

Query: 1308 SPRAVSTTFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGK 1367
              RAVSTTFG RVNVAICLQGT+GPDPTTVYVD+++LRHDRVRLVERG+P SL L ESGK
Sbjct: 1300 PARAVSTTFGCRVNVAICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGK 1359

Query: 1368 ILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDA 1427
            ILPGVKV+I + ETKGP+GDSHLGEIWV+SPH A+GYYT+Y  E L ADHF+ RLSFGD 
Sbjct: 1360 ILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFSARLSFGD- 1418

Query: 1428 AQTLWARTGYLGFVRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIH 1487
             QT+WARTGYLGF+RRTELT A+G RHDALYVVG+LDETLELRG+RYHPIDIETSV R H
Sbjct: 1419 TQTIWARTGYLGFLRRTELTDASGGRHDALYVVGSLDETLELRGMRYHPIDIETSVIRAH 1478

Query: 1488 RSIAECAVFTWTNLLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPI 1547
            RSIAECAVFTWTNLLVVVVEL G EQ+ALDLV LVTNVVLEEHYL+VGVVV+VDPGVIPI
Sbjct: 1479 RSIAECAVFTWTNLLVVVVELDGLEQDALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPI 1538

Query: 1548 NSRGEKQRMHLRDSFLADQLDPIYVAYNM 1576
            NSRGEKQRMHLRD FLADQLDPIYVAYNM
Sbjct: 1539 NSRGEKQRMHLRDGFLADQLDPIYVAYNM 1567


>gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]
          Length = 1110

 Score = 1522 bits (3941), Expect = 0.0
 Identities = 740/1083 (68%), Positives = 890/1083 (82%), Gaps = 24/1083 (2%)

Query: 101  DIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAAL 160
            D+HTEAVQAALAK+KE+KM  PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L
Sbjct: 31   DVHTEAVQAALAKYKERKM--PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRL 88

Query: 161  SAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------SLADV 207
            ++   QS  + E W++R IQGSSTSSSASST SH   + T+              +LA +
Sbjct: 89   TSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGL 148

Query: 208  FANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGV 267
             A+T I+  SAPPDVTT          +  +  + P    V+ + +G +  S+++TADGV
Sbjct: 149  EAHTHIDLHSAPPDVTT--------GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGV 199

Query: 268  PVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGE 327
            PV+SRVS+KIQQLLNTLKRPKRPPLKEFFVDD EE++EV QPDPNQPKPEG + + ++GE
Sbjct: 200  PVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGE 259

Query: 328  PLGVICNWPPALESALQRWGTTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLN 387
            PL      PP+L + LQRWGTTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLN
Sbjct: 260  PLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLN 319

Query: 388  KLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIG 447
            KL +KNEP+LKPGDRVALV+PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+G
Sbjct: 320  KLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVG 379

Query: 448  FLLGSCGIALALTSEVCLKGLPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHIS 507
            FLLGSCG+ LALT++ C KGLPK Q GE+  FKGWP L W+V D K+L+KPPKDW P   
Sbjct: 380  FLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQ 439

Query: 508  PAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGL 567
              GT  AYIEYKTSKEGS +GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGL
Sbjct: 440  DTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGL 499

Query: 568  WHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRD 627
            WHG+  +VMN+MH +SVPY++MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRD
Sbjct: 500  WHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRD 559

Query: 628  VSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVP 687
            VSLSSLRMLIV DGANPWS+SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   
Sbjct: 560  VSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDL 619

Query: 688  GAPLPGRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTD 747
            G P P +A+LSMNGLSYGVIRV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTD
Sbjct: 620  GGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTD 679

Query: 748  EIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVF 807
            E+GEICVSS   G  Y+GL G+TKN FE +PV + G+P+ D PF R+GLLGF+GP +LVF
Sbjct: 680  EVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVF 739

Query: 808  VVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRP 867
            +VGK+DGL++   RRHNADD+VAT LAVE +K VYRGRIAVFSV+V +D+RIV+VAEQRP
Sbjct: 740  IVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRP 799

Query: 868  DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHISQTKQLFLEGSLH 927
            DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPK PLGGIHIS+TKQ FLEG+LH
Sbjct: 800  DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLH 859

Query: 928  PCNILMCPHTCVTNLPKPRQKQPGVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK 987
            PCN+LMCPHTCVTNLPKPRQKQP VGPAS++VGNLVAGKRIAQA+GR+L  +E++D  RK
Sbjct: 860  PCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQARK 919

Query: 988  HQFLAEILQWRAQATPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDKGHLNAGD 1047
              FLA++LQWRA  TPDH LF+LLNAKGT   TA+C+QLHKRAER+A+ L +KG L+ GD
Sbjct: 920  FLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEKGRLSVGD 979

Query: 1048 NVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQ 1107
            +V L+YPPG++LIAAFYGCLY GC+PVTVRPPH QNL  TLPTV+MIV+VSK+AC+LT+Q
Sbjct: 980  HVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLTTQ 1039

Query: 1108 TLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLT 1167
             + RLLRS+EAAAAVD++TWPTI+DTDD+P+K++  +++PP+P++LAYLDFSVSTTG+L 
Sbjct: 1040 AVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLDFSVSTTGILA 1099

Query: 1168 GVK 1170
            GVK
Sbjct: 1100 GVK 1102



 Score =  115 bits (287), Expect = 4e-25
 Identities = 155/664 (23%), Positives = 254/664 (38%), Gaps = 75/664 (11%)

Query: 943  PKPRQKQPGVGPASVMVGN-LVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQA 1001
            P P Q +P     SV+ G  L AG                  + R    LA + +W    
Sbjct: 241  PDPNQPKPEGSETSVLRGEPLTAG------------------VPRPPSLLATLQRW-GTT 281

Query: 1002 TPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDK------GHLNAGDNVVLLYPP 1055
             P       L+  G  V T +  +L  R+ ++A  L +K        L  GD V L++P 
Sbjct: 282  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 341

Query: 1056 G--IELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLL 1113
               +  + AFYGCL A  +PV +  P  +   A    V  ++        LT+    + L
Sbjct: 342  SDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGSCGVFLALTTDACQKGL 400

Query: 1114 RSREAAAAVDVKTWPT----IIDTDDLPRKRLPQLYKP---PTPEMLAYLDFSVSTTGML 1166
               +       K WP     +ID   L +   P+ + P    T    AY+++  S  G  
Sbjct: 401  PKAQTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEGST 458

Query: 1167 TGVKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPP 1226
             GV +SH+++ A CRA+   C    +  +   LD     G     L SV +    V +P 
Sbjct: 459  VGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPY 518

Query: 1227 MELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVA 1286
              ++ N   W+  V  YK R        M         Q      R ++LS +R  +V  
Sbjct: 519  ALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVAD 572

Query: 1287 EERP-RVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ---GTSGPDPTTVYVDLK 1342
               P  ++   +F  +F+  GL P  +     S   + + ++      GP P    + + 
Sbjct: 573  GANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMN 632

Query: 1343 SLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE-TKGPVGDSHLGEIWVNSPHTA 1401
             L +  +R+        L + + G+++PG  V +V  E T        +GEI V+S  T 
Sbjct: 633  GLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATG 692

Query: 1402 SGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAATGERHDALYVVG 1461
            + YY +        +               + RTG LGF+    L          +++VG
Sbjct: 693  TAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFIVG 742

Query: 1462 ALDETLELRGLRYHPID--IETSVS-----RIHRSIAECAVFTWTNL----LVVVVEL-- 1508
             LD  L + G+R H  D  + T+++      ++R     AVF+ T L    +V+V E   
Sbjct: 743  KLD-GLMVTGVRRHNADDVVATALAVEPMKFVYR--GRIAVFSVTVLHDDRIVLVAEQRP 799

Query: 1509 CGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRDSFLADQLD 1568
              SE+++   +  V   +   H + V  + +V    +P    G       +  FL   L 
Sbjct: 800  DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLH 859

Query: 1569 PIYV 1572
            P  V
Sbjct: 860  PCNV 863


>gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]
          Length = 889

 Score = 1153 bits (2982), Expect = 0.0
 Identities = 583/896 (65%), Positives = 699/896 (78%), Gaps = 30/896 (3%)

Query: 1   MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
           MA+RG    P   A LP EVR  LAELELELSEGDITQKGYEKKR+KLL+ Y P  Q  D
Sbjct: 1   MADRGC---PLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID 57

Query: 61  SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
            ++Q E  N+ P PS    +AP K  ++R   +RDER+RSD+HTEAVQAALAK+KE+KM 
Sbjct: 58  PSLQAE--NRIPGPSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM- 113

Query: 121 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
            PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L++   QS  + E W++R IQ
Sbjct: 114 -PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172

Query: 181 GSSTSSSASSTLSHGEVKGTSG-------------SLADVFANTRIENFSAPPDVTTTTS 227
           GSSTSSSASST SH   + T+              +LA + A+T I+  SAPPDVTT   
Sbjct: 173 GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT--- 229

Query: 228 SSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRP 287
                  +  +  + P    V+ + +G +  S+++TADGVPV+SRVS+KIQQLLNTLKRP
Sbjct: 230 -----GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGVPVNSRVSSKIQQLLNTLKRP 283

Query: 288 KRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWG 347
           KRPPLKEFFVDD EE++EV QPDPNQPKPEG + + ++GEPL      PP+L + LQRWG
Sbjct: 284 KRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWG 343

Query: 348 TTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVY 407
           TTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLNKL +KNEP+LKPGDRVALV+
Sbjct: 344 TTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVF 403

Query: 408 PNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKG 467
           PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+GFLLGSCG+ LALT++ C KG
Sbjct: 404 PNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKG 463

Query: 468 LPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVM 527
           LPK Q GE+  FKGWP L W+V D K+L+KPPKDW P     GT  AYIEYKTSKEGS +
Sbjct: 464 LPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523

Query: 528 GVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYS 587
           GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGLWHG+  +VMN+MH +SVPY+
Sbjct: 524 GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583

Query: 588 VMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSV 647
           +MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRDVSLSSLRMLIV DGANPWS+
Sbjct: 584 LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSI 643

Query: 648 SSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVI 707
           SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   G P P +A+LSMNGLSYGVI
Sbjct: 644 SSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVI 703

Query: 708 RVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLA 767
           RV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTDE+GEICVSS   G  Y+GL 
Sbjct: 704 RVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLL 763

Query: 768 GVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADD 827
           G+TKN FE +PV + G+P+ D PF R+GLLGF+GP +LVF+VGK+DGL++   RRHNADD
Sbjct: 764 GITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADD 823

Query: 828 IVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQ 883
           +VAT LAVE +K VYRGRIAVFSV+V +D+RIV+VAEQRPDASEEDSFQWMSRVLQ
Sbjct: 824 VVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQ 879



 Score =  112 bits (279), Expect = 4e-24
 Identities = 132/557 (23%), Positives = 212/557 (38%), Gaps = 60/557 (10%)

Query: 943  PKPRQKQPGVGPASVMVGN-LVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQA 1001
            P P Q +P     SV+ G  L AG                  + R    LA + +W    
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTAG------------------VPRPPSLLATLQRW-GTT 345

Query: 1002 TPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDK------GHLNAGDNVVLLYPP 1055
             P       L+  G  V T +  +L  R+ ++A  L +K        L  GD V L++P 
Sbjct: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405

Query: 1056 G--IELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLL 1113
               +  + AFYGCL A  +PV +  P  +   A    V  ++        LT+    + L
Sbjct: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGSCGVFLALTTDACQKGL 464

Query: 1114 RSREAAAAVDVKTWPT----IIDTDDLPRKRLPQLYKP---PTPEMLAYLDFSVSTTGML 1166
               +       K WP     +ID   L +   P+ + P    T    AY+++  S  G  
Sbjct: 465  PKAQTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEGST 522

Query: 1167 TGVKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPP 1226
             GV +SH+++ A CRA+   C    +  +   LD     G     L SV +    V +P 
Sbjct: 523  VGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPY 582

Query: 1227 MELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVA 1286
              ++ N   W+  V  YK R        M         Q      R ++LS +R  +V  
Sbjct: 583  ALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVAD 636

Query: 1287 EERP-RVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ---GTSGPDPTTVYVDLK 1342
               P  ++   +F  +F+  GL P  +     S   + + ++      GP P    + + 
Sbjct: 637  GANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMN 696

Query: 1343 SLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE-TKGPVGDSHLGEIWVNSPHTA 1401
             L +  +R+        L + + G+++PG  V +V  E T        +GEI V+S  T 
Sbjct: 697  GLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATG 756

Query: 1402 SGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAATGERHDALYVVG 1461
            + YY +        +               + RTG LGF+    L          +++VG
Sbjct: 757  TAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFIVG 806

Query: 1462 ALDETLELRGLRYHPID 1478
             LD  L + G+R H  D
Sbjct: 807  KLD-GLMVTGVRRHNAD 822


>gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]
          Length = 841

 Score = 1088 bits (2814), Expect = 0.0
 Identities = 550/858 (64%), Positives = 662/858 (77%), Gaps = 30/858 (3%)

Query: 1   MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
           MA+RG    P   A LP EVR  LAELELELSEGDITQKGYEKKR+KLL+ Y P  Q  D
Sbjct: 1   MADRGC---PLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID 57

Query: 61  SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
            ++Q E  N+ P PS    +AP K  ++R   +RDER+RSD+HTEAVQAALAK+KE+KM 
Sbjct: 58  PSLQAE--NRIPGPSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM- 113

Query: 121 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
            PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L++   QS  + E W++R IQ
Sbjct: 114 -PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172

Query: 181 GSSTSSSASSTLSHGEVKGTSG-------------SLADVFANTRIENFSAPPDVTTTTS 227
           GSSTSSSASST SH   + T+              +LA + A+T I+  SAPPDVTT   
Sbjct: 173 GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT--- 229

Query: 228 SSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRP 287
                  +  +  + P    V+ + +G +  S+++TADGVPV+SRVS+KIQQLLNTLKRP
Sbjct: 230 -----GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGVPVNSRVSSKIQQLLNTLKRP 283

Query: 288 KRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWG 347
           KRPPLKEFFVDD EE++EV QPDPNQPKPEG + + ++GEPL      PP+L + LQRWG
Sbjct: 284 KRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWG 343

Query: 348 TTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVY 407
           TTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLNKL +KNEP+LKPGDRVALV+
Sbjct: 344 TTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVF 403

Query: 408 PNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKG 467
           PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+GFLLGSCG+ LALT++ C KG
Sbjct: 404 PNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKG 463

Query: 468 LPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVM 527
           LPK Q GE+  FKGWP L W+V D K+L+KPPKDW P     GT  AYIEYKTSKEGS +
Sbjct: 464 LPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523

Query: 528 GVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYS 587
           GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGLWHG+  +VMN+MH +SVPY+
Sbjct: 524 GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583

Query: 588 VMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSV 647
           +MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRDVSLSSLRMLIV DGANPWS+
Sbjct: 584 LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSI 643

Query: 648 SSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVI 707
           SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   G P P +A+LSMNGLSYGVI
Sbjct: 644 SSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVI 703

Query: 708 RVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLA 767
           RV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTDE+GEICVSS   G  Y+GL 
Sbjct: 704 RVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLL 763

Query: 768 GVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADD 827
           G+TKN FE +PV + G+P+ D PF R+GLLGF+GP +LVF+VGK+DGL++   RRHNADD
Sbjct: 764 GITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADD 823

Query: 828 IVATGLAVESIKTVYRGR 845
           +VAT LAVE +K VYRGR
Sbjct: 824 VVATALAVEPMKFVYRGR 841



 Score =  112 bits (279), Expect = 4e-24
 Identities = 132/557 (23%), Positives = 212/557 (38%), Gaps = 60/557 (10%)

Query: 943  PKPRQKQPGVGPASVMVGN-LVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQA 1001
            P P Q +P     SV+ G  L AG                  + R    LA + +W    
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTAG------------------VPRPPSLLATLQRW-GTT 345

Query: 1002 TPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDK------GHLNAGDNVVLLYPP 1055
             P       L+  G  V T +  +L  R+ ++A  L +K        L  GD V L++P 
Sbjct: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405

Query: 1056 G--IELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLL 1113
               +  + AFYGCL A  +PV +  P  +   A    V  ++        LT+    + L
Sbjct: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGSCGVFLALTTDACQKGL 464

Query: 1114 RSREAAAAVDVKTWPT----IIDTDDLPRKRLPQLYKP---PTPEMLAYLDFSVSTTGML 1166
               +       K WP     +ID   L +   P+ + P    T    AY+++  S  G  
Sbjct: 465  PKAQTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEGST 522

Query: 1167 TGVKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPP 1226
             GV +SH+++ A CRA+   C    +  +   LD     G     L SV +    V +P 
Sbjct: 523  VGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPY 582

Query: 1227 MELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVA 1286
              ++ N   W+  V  YK R        M         Q      R ++LS +R  +V  
Sbjct: 583  ALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVAD 636

Query: 1287 EERP-RVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ---GTSGPDPTTVYVDLK 1342
               P  ++   +F  +F+  GL P  +     S   + + ++      GP P    + + 
Sbjct: 637  GANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMN 696

Query: 1343 SLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE-TKGPVGDSHLGEIWVNSPHTA 1401
             L +  +R+        L + + G+++PG  V +V  E T        +GEI V+S  T 
Sbjct: 697  GLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATG 756

Query: 1402 SGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAATGERHDALYVVG 1461
            + YY +        +               + RTG LGF+    L          +++VG
Sbjct: 757  TAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFIVG 806

Query: 1462 ALDETLELRGLRYHPID 1478
             LD  L + G+R H  D
Sbjct: 807  KLD-GLMVTGVRRHNAD 822


>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
          Length = 798

 Score = 1055 bits (2729), Expect = 0.0
 Identities = 536/845 (63%), Positives = 638/845 (75%), Gaps = 47/845 (5%)

Query: 1   MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
           MA+RG    P   A LP EVR  LAELELELSEGDITQKGYEKKR+KLL+ Y P  Q  D
Sbjct: 1   MADRGC---PLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID 57

Query: 61  SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
            ++Q E  N+ P PS    +AP K  ++R   +RDER+RSD+HTEAVQAALAK+KE+KM 
Sbjct: 58  PSLQAE--NRIPGPSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM- 113

Query: 121 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
            PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L++   QS  + E W++R IQ
Sbjct: 114 -PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172

Query: 181 GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI 240
           GSSTSSSASST SH   + T+   A           +A P    TT+ +   +       
Sbjct: 173 GSSTSSSASSTSSHPGGRPTTAPSA-----------AATPGAAATTALAGLEA------- 214

Query: 241 DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS 300
                                 T  GVPV+SRVS+KIQQLLNTLKRPKRPPLKEFFVDD 
Sbjct: 215 ---------------------HTHIGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDF 253

Query: 301 EEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD 360
           EE++EV QPDPNQPKPEG + + ++GEPL      PP+L + LQRWGTTQ K  CLTALD
Sbjct: 254 EELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALD 313

Query: 361 MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFY 420
            TGK VYTLTYGKLWSRSLKLAYTLLNKL +KNEP+LKPGDRVALV+PN+DPVMFMVAFY
Sbjct: 314 TTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFY 373

Query: 421 GCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIVQFK 480
           GCLLAE++PVPIEVPLTRKDAG QQ+GFLLGSCG+ LALT++ C KGLPK Q GE+  FK
Sbjct: 374 GCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFK 433

Query: 481 GWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC 540
           GWP L W+V D K+L+KPPKDW P     GT  AYIEYKTSKEGS +GVTVS  ++L+ C
Sbjct: 434 GWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQC 493

Query: 541 QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRV 600
           +AL+QAC YSE ET+ NVLDFK+DAGLWHG+  +VMN+MH +SVPY++MK  PLSW+Q+V
Sbjct: 494 RALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKV 553

Query: 601 HAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSH 660
             +KA+ ALVK RD+HW+++A R QRDVSLSSLRMLIV DGANPWS+SSCDAFL++FQS 
Sbjct: 554 CFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 613

Query: 661 GLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV 720
           GL+PE ICPCA+S EA+TVAIRRP   G P P +A+LSMNGLSYGVIRV+TE+K S LTV
Sbjct: 614 GLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTV 673

Query: 721 QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVN 780
           QDVG VMPG  +C+VK +G P LCKTDE+GEICVSS   G  Y+GL G+TKN FE +PV 
Sbjct: 674 QDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVT 733

Query: 781 SAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKT 840
           + G+P+ D PF R+GLLGF+GP +LVF+VGK+DGL++   RRHNADD+VAT LAVE +K 
Sbjct: 734 TGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKF 793

Query: 841 VYRGR 845
           VYRGR
Sbjct: 794 VYRGR 798



 Score =  112 bits (279), Expect = 4e-24
 Identities = 132/557 (23%), Positives = 212/557 (38%), Gaps = 60/557 (10%)

Query: 943  PKPRQKQPGVGPASVMVGN-LVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQA 1001
            P P Q +P     SV+ G  L AG                  + R    LA + +W    
Sbjct: 262  PDPNQPKPEGSETSVLRGEPLTAG------------------VPRPPSLLATLQRW-GTT 302

Query: 1002 TPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDK------GHLNAGDNVVLLYPP 1055
             P       L+  G  V T +  +L  R+ ++A  L +K        L  GD V L++P 
Sbjct: 303  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 362

Query: 1056 G--IELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLL 1113
               +  + AFYGCL A  +PV +  P  +   A    V  ++        LT+    + L
Sbjct: 363  SDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGSCGVFLALTTDACQKGL 421

Query: 1114 RSREAAAAVDVKTWPT----IIDTDDLPRKRLPQLYKP---PTPEMLAYLDFSVSTTGML 1166
               +       K WP     +ID   L +   P+ + P    T    AY+++  S  G  
Sbjct: 422  PKAQTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEGST 479

Query: 1167 TGVKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPP 1226
             GV +SH+++ A CRA+   C    +  +   LD     G     L SV +    V +P 
Sbjct: 480  VGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPY 539

Query: 1227 MELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVA 1286
              ++ N   W+  V  YK R        M         Q      R ++LS +R  +V  
Sbjct: 540  ALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVAD 593

Query: 1287 EERP-RVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ---GTSGPDPTTVYVDLK 1342
               P  ++   +F  +F+  GL P  +     S   + + ++      GP P    + + 
Sbjct: 594  GANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMN 653

Query: 1343 SLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE-TKGPVGDSHLGEIWVNSPHTA 1401
             L +  +R+        L + + G+++PG  V +V  E T        +GEI V+S  T 
Sbjct: 654  GLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATG 713

Query: 1402 SGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAATGERHDALYVVG 1461
            + YY +        +               + RTG LGF+    L          +++VG
Sbjct: 714  TAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFIVG 763

Query: 1462 ALDETLELRGLRYHPID 1478
             LD  L + G+R H  D
Sbjct: 764  KLD-GLMVTGVRRHNAD 779


>gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]
          Length = 812

 Score = 1030 bits (2664), Expect = 0.0
 Identities = 522/818 (63%), Positives = 628/818 (76%), Gaps = 30/818 (3%)

Query: 1   MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
           MA+RG    P   A LP EVR  LAELELELSEGDITQKGYEKKR+KLL+ Y P  Q  D
Sbjct: 1   MADRGC---PLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID 57

Query: 61  SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
            ++Q E  N+ P PS    +AP K  ++R   +RDER+RSD+HTEAVQAALAK+KE+KM 
Sbjct: 58  PSLQAE--NRIPGPSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM- 113

Query: 121 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
            PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L++   QS  + E W++R IQ
Sbjct: 114 -PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172

Query: 181 GSSTSSSASSTLSHGEVKGTSG-------------SLADVFANTRIENFSAPPDVTTTTS 227
           GSSTSSSASST SH   + T+              +LA + A+T I+  SAPPDVTT   
Sbjct: 173 GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT--- 229

Query: 228 SSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRP 287
                  +  +  + P    V+ + +G +  S+++TADGVPV+SRVS+KIQQLLNTLKRP
Sbjct: 230 -----GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGVPVNSRVSSKIQQLLNTLKRP 283

Query: 288 KRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWG 347
           KRPPLKEFFVDD EE++EV QPDPNQPKPEG + + ++GEPL      PP+L + LQRWG
Sbjct: 284 KRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWG 343

Query: 348 TTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVY 407
           TTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLNKL +KNEP+LKPGDRVALV+
Sbjct: 344 TTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVF 403

Query: 408 PNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKG 467
           PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+GFLLGSCG+ LALT++ C KG
Sbjct: 404 PNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKG 463

Query: 468 LPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVM 527
           LPK Q GE+  FKGWP L W+V D K+L+KPPKDW P     GT  AYIEYKTSKEGS +
Sbjct: 464 LPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523

Query: 528 GVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYS 587
           GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGLWHG+  +VMN+MH +SVPY+
Sbjct: 524 GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583

Query: 588 VMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSV 647
           +MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRDVSLSSLRMLIV DGANPWS+
Sbjct: 584 LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSI 643

Query: 648 SSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVI 707
           SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   G P P +A+LSMNGLSYGVI
Sbjct: 644 SSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVI 703

Query: 708 RVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLA 767
           RV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTDE+GEICVSS   G  Y+GL 
Sbjct: 704 RVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLL 763

Query: 768 GVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSL 805
           G+TKN FE +PV + G+P+ D PF R+GLLGF+GP S+
Sbjct: 764 GITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPVSM 801



 Score =  108 bits (271), Expect = 3e-23
 Identities = 123/529 (23%), Positives = 201/529 (37%), Gaps = 49/529 (9%)

Query: 943  PKPRQKQPGVGPASVMVGN-LVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQA 1001
            P P Q +P     SV+ G  L AG                  + R    LA + +W    
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTAG------------------VPRPPSLLATLQRW-GTT 345

Query: 1002 TPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDK------GHLNAGDNVVLLYPP 1055
             P       L+  G  V T +  +L  R+ ++A  L +K        L  GD V L++P 
Sbjct: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405

Query: 1056 G--IELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLL 1113
               +  + AFYGCL A  +PV +  P  +   A    V  ++        LT+    + L
Sbjct: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGSCGVFLALTTDACQKGL 464

Query: 1114 RSREAAAAVDVKTWPT----IIDTDDLPRKRLPQLYKP---PTPEMLAYLDFSVSTTGML 1166
               +       K WP     +ID   L +   P+ + P    T    AY+++  S  G  
Sbjct: 465  PKAQTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEGST 522

Query: 1167 TGVKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPP 1226
             GV +SH+++ A CRA+   C    +  +   LD     G     L SV +    V +P 
Sbjct: 523  VGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPY 582

Query: 1227 MELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVA 1286
              ++ N   W+  V  YK R        M         Q      R ++LS +R  +V  
Sbjct: 583  ALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVAD 636

Query: 1287 EERP-RVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ---GTSGPDPTTVYVDLK 1342
               P  ++   +F  +F+  GL P  +     S   + + ++      GP P    + + 
Sbjct: 637  GANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMN 696

Query: 1343 SLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE-TKGPVGDSHLGEIWVNSPHTA 1401
             L +  +R+        L + + G+++PG  V +V  E T        +GEI V+S  T 
Sbjct: 697  GLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATG 756

Query: 1402 SGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT 1450
            + YY +        +               + RTG LGF+    +++ T
Sbjct: 757  TAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPVSMSSCT 805


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 49/167 (29%), Positives = 72/167 (43%), Gaps = 20/167 (11%)

Query: 176 NRSIQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSI 235
           NRSI  SS+SSS+SS+ S      +S               S+    ++++SSSSSSSS 
Sbjct: 143 NRSIHTSSSSSSSSSSSSSSSSSSSSS--------------SSSSSSSSSSSSSSSSSSS 188

Query: 236 RPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPK-RPPLKE 294
              +   P   + +   K S  S    +A   P  SR   K  +   + K+PK   PLKE
Sbjct: 189 SSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEP--SRDHNKSSK--ESSKKPKENKPLKE 244

Query: 295 FFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALES 341
             +       E P+P   +PKP+   +T   G+        PP  +S
Sbjct: 245 EKIVPKMAFKE-PKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDS 290


>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
          Length = 1251

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 58/286 (20%), Positives = 116/286 (40%), Gaps = 33/286 (11%)

Query: 18  PEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQTPAPSAA 77
           P  + + A  + +LS+  I ++G E +             ET+S V++ +R  T  P  +
Sbjct: 293 PASKPEPARAKAKLSKFSIPKQGEESRSG-----------ETNSCVEEIIREMTWLPPLS 341

Query: 78  QTSAPSKYHRTRSGGA-RDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPA 136
              AP K   T+     +D +  S  H         K  + +   P      ++ ++   
Sbjct: 342 AIQAPGKVEPTKFPFPNKDSQLVSSGHNNP------KKGDAEPESPDNGTSNTSMLEDDL 395

Query: 137 DACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGE 196
              +  + +     + +  R  + SA +QQ   N  + +  S +GSS+SSS+ S+ S  +
Sbjct: 396 KLSSDEEENEQQAAQRTALRALSDSAVVQQP--NCRTSVPSS-KGSSSSSSSGSSSSSSD 452

Query: 197 VKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSS------IRPANIDLPPSGIVKG 250
            + +SGS ++  +++     S PP  ++  +  +SS+       +   N   PP  I   
Sbjct: 453 SESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKPPILIQNE 512

Query: 251 MHKGSNRSSLMDTADGVPVSSRV------STKIQQLLNTLKRPKRP 290
            H   +        + V    +V      S + +++ +T K  +RP
Sbjct: 513 SHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRP 558


>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
          Length = 1226

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 58/286 (20%), Positives = 116/286 (40%), Gaps = 33/286 (11%)

Query: 18  PEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQTPAPSAA 77
           P  + + A  + +LS+  I ++G E +             ET+S V++ +R  T  P  +
Sbjct: 268 PASKPEPARAKAKLSKFSIPKQGEESRSG-----------ETNSCVEEIIREMTWLPPLS 316

Query: 78  QTSAPSKYHRTRSGGA-RDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPA 136
              AP K   T+     +D +  S  H         K  + +   P      ++ ++   
Sbjct: 317 AIQAPGKVEPTKFPFPNKDSQLVSSGHNNP------KKGDAEPESPDNGTSNTSMLEDDL 370

Query: 137 DACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGE 196
              +  + +     + +  R  + SA +QQ   N  + +  S +GSS+SSS+ S+ S  +
Sbjct: 371 KLSSDEEENEQQAAQRTALRALSDSAVVQQP--NCRTSVPSS-KGSSSSSSSGSSSSSSD 427

Query: 197 VKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSS------IRPANIDLPPSGIVKG 250
            + +SGS ++  +++     S PP  ++  +  +SS+       +   N   PP  I   
Sbjct: 428 SESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKPPILIQNE 487

Query: 251 MHKGSNRSSLMDTADGVPVSSRV------STKIQQLLNTLKRPKRP 290
            H   +        + V    +V      S + +++ +T K  +RP
Sbjct: 488 SHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRP 533


>gi|66730481 neuregulin 3 [Homo sapiens]
          Length = 696

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 45/179 (25%), Positives = 67/179 (37%), Gaps = 10/179 (5%)

Query: 61  SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120
           S+  K +   T   S    + PS      +GGA   R  + I T       A  +     
Sbjct: 119 SSFPKAMETTTTTTSTTSPATPS------AGGAASSRTPNRISTRLTTITRAPTRFPGHR 172

Query: 121 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180
           +P+    RST  ++ A   T P T++      +L  +  +      S Q   SW   +  
Sbjct: 173 VPIRASPRSTTARNTAAPATVPSTTAPFFSSSTLGSRPPVPGT--PSTQAMPSWPTAAYA 230

Query: 181 GSST--SSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRP 237
            SS    S+ S TLS  +   +S S +   A T     S  P   TTT S+  S   +P
Sbjct: 231 TSSYLHDSTPSWTLSPFQDAASSSSSSSSSATTTTPETSTSPKFHTTTYSTERSEHFKP 289


>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
          Length = 1992

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 52/225 (23%), Positives = 90/225 (40%), Gaps = 27/225 (12%)

Query: 54  PQTQETDSAVQKELRNQTPAPS-----AAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQ 108
           PQ ++ D A   E +     P        + SA   Y+RT S  +  ++ ++  HTE+  
Sbjct: 44  PQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSA-KKPKALQHTESPS 102

Query: 109 AALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSL 168
                H +        +K+R    +    +   P TS A       R+  A   +  Q  
Sbjct: 103 ETNKPHSK--------SKKRHLDQEQQLKSAQSPSTSKAHT-----RKSGATGGSRSQKR 149

Query: 169 QNAESWINRSIQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSS 228
           +  ES   +S  GS ++ +   +    ++   S + A    +T  ++ SA        S+
Sbjct: 150 KRTESSCVKSGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSSA-------AST 202

Query: 229 SSSSSSIRPANIDLPPSGIVK-GMHKGSNRSSLMDTADGVPVSSR 272
           SSSSS++  A+  +PP   VK G  +   R S   ++     SSR
Sbjct: 203 SSSSSAVASASSTVPPGARVKQGKDQNKARRSRSASSPSPRRSSR 247


>gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]
          Length = 1523

 Score = 39.7 bits (91), Expect = 0.023
 Identities = 65/304 (21%), Positives = 109/304 (35%), Gaps = 41/304 (13%)

Query: 22   AQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKE-----LRNQTPAPSA 76
            +Q    E+E   GD     Y +  S      SP     +S    E     + +  P P  
Sbjct: 956  SQYCRKEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDP 1015

Query: 77   AQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPA 136
            A   A S  H     G  ++            ++L +  EQ+  L        T  +SP 
Sbjct: 1016 APRFATSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFL---RHHFETLTESPC 1072

Query: 137  DACTPP---DTSSASEDEGSLRRQAALSAALQQSLQNAESWIN----RSIQGSSTSSSAS 189
                P    D  ++  ++     + ++S     SLQ A  + +    R+ Q     S   
Sbjct: 1073 RELFPAALGDVEASEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQ-CLVKSPEV 1131

Query: 190  STLSHGEVKGTSGS----------LADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPAN 239
              +  G  +  +G+          LA   A   +E +  PP   T+ +S   +SS+ P +
Sbjct: 1132 KLMDRGGSQPRAGTGYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTD 1191

Query: 240  IDL------PPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQ------QLLNTLKRP 287
             +L      P  G+ +G+H  S  S +  TA      +R+S  I        ++ TL +P
Sbjct: 1192 RNLPTPTSAPTPGLAQGVHAPSTCSYMEATASS---RARISRSISLGDSEGPIVATLAQP 1248

Query: 288  KRPP 291
             R P
Sbjct: 1249 LRRP 1252


>gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]
          Length = 1518

 Score = 39.7 bits (91), Expect = 0.023
 Identities = 66/301 (21%), Positives = 109/301 (36%), Gaps = 40/301 (13%)

Query: 22   AQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKE-----LRNQTPAPSA 76
            +Q    E+E   GD     Y +  S      SP     +S    E     + +  P P  
Sbjct: 956  SQYCRKEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDP 1015

Query: 77   AQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPA 136
            A   A S  H     G  ++            ++L +  EQ+  L        T  +SP 
Sbjct: 1016 APRFATSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFL---RHHFETLTESPC 1072

Query: 137  DACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWIN----RSIQGSSTSSSASSTL 192
             A    + S A  ++     + ++S     SLQ A  + +    R+ Q     S     +
Sbjct: 1073 RALGDVEASEA--EDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQ-CLVKSPEVKLM 1129

Query: 193  SHGEVKGTSGS----------LADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDL 242
              G  +  +G+          LA   A   +E +  PP   T+ +S   +SS+ P + +L
Sbjct: 1130 DRGGSQPRAGTGYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNL 1189

Query: 243  ------PPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQ------QLLNTLKRPKRP 290
                  P  G+ +G+H  S  S +  TA      +R+S  I        ++ TL +P R 
Sbjct: 1190 PTPTSAPTPGLAQGVHAPSTCSYMEATASS---RARISRSISLGDSEGPIVATLAQPLRR 1246

Query: 291  P 291
            P
Sbjct: 1247 P 1247


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 39.3 bits (90), Expect = 0.030
 Identities = 49/217 (22%), Positives = 85/217 (39%), Gaps = 2/217 (0%)

Query: 18   PEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQTPAPSAA 77
            P    + AEL ++L    +T    +K +  LL    P          K L +    P AA
Sbjct: 2451 PRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEP--KSLLSLGSYPPAA 2508

Query: 78   QTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPAD 137
             +S P       + G   +     +  E      +  K Q           S+   S + 
Sbjct: 2509 GSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSS 2568

Query: 138  ACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEV 197
            + +   +SS SE EG                +N  +  +R+   +S+SSS+SS+ S    
Sbjct: 2569 SSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSS 2628

Query: 198  KGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSS 234
              +S S +   +++   + S+    ++++SSSSSSSS
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665



 Score = 36.6 bits (83), Expect = 0.20
 Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 1/139 (0%)

Query: 137  DACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGE 196
            D    P      ED G+ +      A  Q   + +ES  + S   SS+SSS+SS+ S  E
Sbjct: 2524 DLAQEPGPGLTFEDSGNPKSPDKAQAE-QDGAEESESSSSSSSGSSSSSSSSSSSGSETE 2582

Query: 197  VKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSN 256
             +       D    T   N SA      + +SSSSSSS   ++     S         S+
Sbjct: 2583 GEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642

Query: 257  RSSLMDTADGVPVSSRVST 275
             SS   ++     SS  S+
Sbjct: 2643 SSSSSSSSSSSSSSSSSSS 2661


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 38.9 bits (89), Expect = 0.040
 Identities = 50/226 (22%), Positives = 85/226 (37%), Gaps = 9/226 (3%)

Query: 50   SPYSPQTQETDSAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQA 109
            SP+S     T ++ Q       P PS  QT+ P+      +       +   I T    A
Sbjct: 1976 SPFSSTGPMTATSFQTT--TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMA 2033

Query: 110  ALAK-HKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSL 168
              A  H      +P PT  ++T     A   T   TS  S+   S     A S+ +    
Sbjct: 2034 TSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVT-TSGTSQTHSSFSTATASSSFI---- 2088

Query: 169  QNAESWINRSIQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSS 228
             ++ SW+ ++      SS  ++ L H     T  S  +  +++   + SAP  V++   S
Sbjct: 2089 -SSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPS 2147

Query: 229  SSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVS 274
            S SS      ++    S +   +H  +  S    +    P ++ VS
Sbjct: 2148 SHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193



 Score = 31.6 bits (70), Expect = 6.3
 Identities = 48/240 (20%), Positives = 79/240 (32%), Gaps = 21/240 (8%)

Query: 2    AERGLEPSPAAVA-ALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60
            A  GL P+    + A  P V           +    T       R+ +  P +P T  T 
Sbjct: 1282 ATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLP-TPATSGTS 1340

Query: 61   SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDE--RYRSDIHTEAVQAALAKHKEQK 118
              + K    + P  +A QT+ P     + +G    +  +      TE  Q          
Sbjct: 1341 PTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTR-------- 1392

Query: 119  MALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRS 178
                  T    T  Q+P    +PP   S     G +   +  +     +  + E+ +   
Sbjct: 1393 ------TTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTH 1446

Query: 179  IQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVT-TTTSSSSSSSSIRP 237
            +   STS    ST  H  +  T   +A   +N      + PP  T   T S+ ++  I P
Sbjct: 1447 VPPFSTSLVTPST--HTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 38.9 bits (89), Expect = 0.040
 Identities = 44/211 (20%), Positives = 86/211 (40%), Gaps = 20/211 (9%)

Query: 55  QTQETDSAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKH 114
           ++  T S       +++  PS+   +A +    T S GA      ++  +  V + ++  
Sbjct: 229 ESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTA---TNSESSTVSSGISTV 285

Query: 115 KEQKMALPMP-----TKRRSTFVQSPADACTPPDTSSASEDEGSLRR-QAALSAALQQSL 168
              + + P       T   S+   S A+  T  D+S+ S    +    +++ +++   + 
Sbjct: 286 TNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTA 345

Query: 169 QNAESWINRSIQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSS 228
            N+ES        S+TSS AS+  + G    +SG+      N+     S+     TT+ S
Sbjct: 346 TNSES--------STTSSGASTATNSGSSTTSSGT--STATNSESSTVSSGASTATTSES 395

Query: 229 SSSSSSIRPANIDLPPSGIVKGMHKGSNRSS 259
           S++SS    A  +   S +  G    +N  S
Sbjct: 396 STTSSGASTAT-NSESSTVSSGASTATNSES 425



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 36/147 (24%), Positives = 61/147 (41%), Gaps = 9/147 (6%)

Query: 137 DACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRS-IQGSSTSSSASSTLSHG 195
           +A T  + +S S + GS    +  S A         S ++ + I GSS +S+  S +++ 
Sbjct: 19  EAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNS 78

Query: 196 EVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPA---NIDLPPSGIVKGMH 252
           E   TS  ++    N+     S+   + T + SS++SS    A       P SG     +
Sbjct: 79  EFHTTSSGISTA-TNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATN 137

Query: 253 KGSNR----SSLMDTADGVPVSSRVST 275
             S+     +S    +D    SS  ST
Sbjct: 138 SDSSTTSSGASTATNSDSSTTSSEAST 164



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 39/168 (23%), Positives = 62/168 (36%), Gaps = 20/168 (11%)

Query: 55  QTQETDSAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKH 114
           ++    S +     +++  PS+   +A +    T S GA      SD  T +  A+ A +
Sbjct: 274 ESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTAT-NSDSSTTSSGASTATN 332

Query: 115 KEQKMA---LPMPTKRRSTFVQSPADACT-------PPDTSSASEDEGSLRRQAALSAAL 164
            E           T   S+   S A   T          TS+A+  E S     A +A  
Sbjct: 333 SESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATT 392

Query: 165 QQS---------LQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSGS 203
            +S           N+ES    S   ++T+S +S+T S       SGS
Sbjct: 393 SESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGS 440


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 38.5 bits (88), Expect = 0.052
 Identities = 57/257 (22%), Positives = 97/257 (37%), Gaps = 17/257 (6%)

Query: 9    SPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQE--TDSAVQKE 66
            SP A A  P   R+  + L  E +    +    +       S  S +++E  T  +    
Sbjct: 1890 SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH 1949

Query: 67   LRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTK 126
              +  P+ ++A    P+ YH +    A      S   +   + + A H  Q     +   
Sbjct: 1950 TISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 2009

Query: 127  RRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSS 186
             RST      ++ T P +S      GS+   A   +     L    +  + S +  +T+ 
Sbjct: 2010 ARSTTSVLLGESTTSPISS------GSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTL 2063

Query: 187  SASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTT--TSSSSSSSSIRPANID--- 241
            S +ST S G  + ++ S     +     + +A PD TTT   S  S++S   P + D   
Sbjct: 2064 SPASTTSSGVSEESTTS----HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2119

Query: 242  LPPSGIVKGMHKGSNRS 258
            LP S    G  + S  S
Sbjct: 2120 LPASTTTSGPSQESTTS 2136



 Score = 38.1 bits (87), Expect = 0.068
 Identities = 56/264 (21%), Positives = 97/264 (36%), Gaps = 31/264 (11%)

Query: 9    SPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELR 68
            SP A A  P   R+  + L  E +        Y        + + P++  T    ++   
Sbjct: 3447 SPVATATTPSPARSTTSGLVEESTT-------YHSSPGSTQTMHFPESDTTSGRGEESTT 3499

Query: 69   NQT---------PAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKM 119
            + +         P+ ++A    P+ YH +    A      S   +   + + A H  Q  
Sbjct: 3500 SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 3559

Query: 120  ALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSI 179
               +    RST      ++ T P +S      GS+   A   +     L    +  + S 
Sbjct: 3560 TGTIVLPARSTTSVLLGESTTSPISS------GSMETTALPGSTTTPGLSEKSTTFHSSP 3613

Query: 180  QGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTT--TSSSSSSSSIRP 237
            +  +T+ S +ST S G  + ++ S     +     + +A PD TTT   S  S++S   P
Sbjct: 3614 RSPATTLSPASTTSSGVSEESTTS----HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 3669

Query: 238  ANID---LPPSGIVKGMHKGSNRS 258
             + D   LP S    G  + S  S
Sbjct: 3670 GSTDTTLLPASTTTSGSSQESTTS 3693



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 15/195 (7%)

Query: 69   NQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRR 128
            +  P+ ++A    P+ YH +    A      S   +   + + A H  Q     +    R
Sbjct: 869  SSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPAR 928

Query: 129  STFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSA 188
            ST      ++ T P +S      GS+   A   +     L    +  + S +  +T+ S 
Sbjct: 929  STTSVLLGESTTSPISS------GSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSP 982

Query: 189  SSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTT--TSSSSSSSSIRPANID---LP 243
            +ST S G  + ++ S     +     + +A PD TTT   S  S++S   P + D   LP
Sbjct: 983  ASTTSSGVSEESTTSR----SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 1038

Query: 244  PSGIVKGMHKGSNRS 258
             S    G  + S  S
Sbjct: 1039 ASTTTSGPSQESTTS 1053


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 38.5 bits (88), Expect = 0.052
 Identities = 50/227 (22%), Positives = 92/227 (40%), Gaps = 35/227 (15%)

Query: 63  VQKELRNQTPAPSAAQTSAPSKYHRTR-----SGGA-------RDERYRSDIHTEAVQAA 110
           + KE   +    ++   +A SK H TR     S G+       + +RYR++ +  +++  
Sbjct: 434 IAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQRYRNEENDSSLKTG 493

Query: 111 LAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQN 170
           L K +  KMA P P + R T  +S  +A +   + S   +E S   Q      +      
Sbjct: 494 LEKMRSGKMA-PKP-QSRCTSTRSAGEAPSENQSPSKGPEEASSEVQDTNEVHVPGDQDE 551

Query: 171 AESWINRSIQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSS 230
            ++      +GS  + S   TL+  +   +S S+  +          +  D+ ++ S  S
Sbjct: 552 PQT---LGKKGSKNNISVYMTLNQKKSDSSSASVCSI---------DSTDDLKSSNSECS 599

Query: 231 SSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKI 277
           SS S      D PP      MH  S  S+   + +   +S+ +  K+
Sbjct: 600 SSES-----FDFPPG----SMHAPSTSSTSSSSKEEKKLSNSLKMKV 637


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
            sapiens]
          Length = 480

 Score = 38.1 bits (87), Expect = 0.068
 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 9/91 (9%)

Query: 1025 QLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNL 1084
            QL K+A   AS+L D   L+ GD ++++ PP  E   A++ CL    + +T  P   Q  
Sbjct: 93   QLSKKA---ASILSDTCALSHGDRLMIILPPTPE---AYWICLACVRLGITFVPGSPQ-- 144

Query: 1085 TATLPTVRMIVDVSKAACILTSQTLMRLLRS 1115
              T   +R  + +SKA CI+ ++ +  ++ S
Sbjct: 145  -LTAKKIRYQLRMSKAQCIVANEAMAPVVNS 174


>gi|55742730 storkhead box 2 [Homo sapiens]
          Length = 926

 Score = 38.1 bits (87), Expect = 0.068
 Identities = 40/156 (25%), Positives = 69/156 (44%), Gaps = 10/156 (6%)

Query: 46  SKLLSPYSPQTQETD-SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHT 104
           + +L  + P T E D S    + R + P P  ++ S+ SK HR+ S   +D R R++   
Sbjct: 427 TNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHS-HTQDRRSRNERSN 485

Query: 105 EAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASE--DEGSLR--RQAAL 160
           +A + + +    +    P+      T  +  A+ C+  D + +    D+ +LR  +  +L
Sbjct: 486 KAKERSRSMDNSKG---PLGASSLGT-PEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSL 541

Query: 161 SAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGE 196
             A   S    E  I   + GS   SSA S L  G+
Sbjct: 542 QRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGK 577


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 37.7 bits (86), Expect = 0.088
 Identities = 53/249 (21%), Positives = 101/249 (40%), Gaps = 24/249 (9%)

Query: 53  SPQTQETDSAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERY----RSDIHTEAVQ 108
           S +   T  + +   + Q  + S    SAP    RT S  +  ++     +S    E V+
Sbjct: 283 SSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVK 342

Query: 109 AALAKHKEQKMALPMPTK--------RRSTFVQSPADACTPPDTSSASEDEGSLRRQAAL 160
           A  ++ +E K AL +           +  +   SP+++ +  D+SS S+ E S       
Sbjct: 343 AE-SEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGP 401

Query: 161 SAALQQSLQNAESWINRSIQG----SSTSSSASSTLSHGEVKGTSGSLADVFANTRIENF 216
             ++ + LQ+ ES  + S  G      T+    S LS       S S +D  A++ + + 
Sbjct: 402 LRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSF------SDSESDNSADSSLPSR 455

Query: 217 SAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTK 276
             PP       +S  S    P +   P   + KG +  +    L++    + ++ R    
Sbjct: 456 EPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRL-MALRERNV 514

Query: 277 IQQLLNTLK 285
           +QQ++N ++
Sbjct: 515 LQQIVNLIE 523


>gi|38202211 N-acetylglucosamine-1-phosphate transferase [Homo
           sapiens]
          Length = 1256

 Score = 37.7 bits (86), Expect = 0.088
 Identities = 19/59 (32%), Positives = 31/59 (52%)

Query: 13  VAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQT 71
           ++ LP + +  L  L+L+L  GDIT KGY   +S LL  +   +Q      Q  + ++T
Sbjct: 700 ISLLPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFLMNSQHAKIKNQAIITDET 758


>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 6 [Homo sapiens]
          Length = 305

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 19/141 (13%)

Query: 100 SDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTS--SASEDEGSLRRQ 157
           S +  +++      +K+     P PTKR+    +   D       +  S+ +D G  + +
Sbjct: 4   SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63

Query: 158 AALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFS 217
              SA+   S   + S        SSTSSS SST S G   G+S S A         + S
Sbjct: 64  KRRSASSGSSSTRSRS--------SSTSSSGSST-STGSSSGSSSSSAS--------SRS 106

Query: 218 APPDVTTTTSSSSSSSSIRPA 238
                + ++SSSSSS S  P+
Sbjct: 107 GSSSTSRSSSSSSSSGSPSPS 127


>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 2 [Homo sapiens]
          Length = 305

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 19/141 (13%)

Query: 100 SDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTS--SASEDEGSLRRQ 157
           S +  +++      +K+     P PTKR+    +   D       +  S+ +D G  + +
Sbjct: 4   SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63

Query: 158 AALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFS 217
              SA+   S   + S        SSTSSS SST S G   G+S S A         + S
Sbjct: 64  KRRSASSGSSSTRSRS--------SSTSSSGSST-STGSSSGSSSSSAS--------SRS 106

Query: 218 APPDVTTTTSSSSSSSSIRPA 238
                + ++SSSSSS S  P+
Sbjct: 107 GSSSTSRSSSSSSSSGSPSPS 127


>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 6 [Homo sapiens]
          Length = 1093

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 23/159 (14%)

Query: 87  RTRSGGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSS 146
           R+RS     ++ +   H E  Q    K KE+   L    K+R    +SP    TPP   +
Sbjct: 217 RSRSASPSTQQEKHPTHHERGQKKSRKDKER---LKQKHKKRP---ESPPSILTPPVVPT 270

Query: 147 ASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSGSLAD 206
           A +   S    +   A+ Q++        + S + S    S+S +LSH   K +SG    
Sbjct: 271 ADKVSSSASSSSHHEASTQET--------SESSRESKGKKSSSHSLSHKGKKLSSGKGVS 322

Query: 207 VFANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDLPPS 245
            F +            ++++SSSSS    +PA   L  S
Sbjct: 323 SFTSA---------SSSSSSSSSSSGGPFQPAVSSLQSS 352


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 49/210 (23%), Positives = 83/210 (39%), Gaps = 31/210 (14%)

Query: 18   PEVRAQLAELE---LELSEGDITQKGYEKKRSKL----LSPYSPQTQETDSAVQKEL--- 67
            P   + LA+LE   L + E   +    EK   K     +SP  P+ QE   ++ + L   
Sbjct: 1403 PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEIT 1462

Query: 68   ------------RNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHK 115
                        R  T    + Q    SK H+ +S       +  DI T        +  
Sbjct: 1463 ISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS------EFVDDITTRREPYDSVEES 1516

Query: 116  EQKMALPMPTKRRSTFV-QSPADACTPPDTSSASEDEGSLRRQ-AALSAALQQSLQNAES 173
             +    P+P ++R T V  S +D     D+  + E+E  +R+Q   +SA    S    + 
Sbjct: 1517 SESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDE 1576

Query: 174  WINRSIQG-SSTSSSASSTLSHGEVKGTSG 202
            +I   ++  SS++ S     + G+ K T+G
Sbjct: 1577 FIRNQLKEISSSTESQKKEETKGKGKITAG 1606


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 37.4 bits (85), Expect = 0.12
 Identities = 49/210 (23%), Positives = 83/210 (39%), Gaps = 31/210 (14%)

Query: 18   PEVRAQLAELE---LELSEGDITQKGYEKKRSKL----LSPYSPQTQETDSAVQKEL--- 67
            P   + LA+LE   L + E   +    EK   K     +SP  P+ QE   ++ + L   
Sbjct: 1403 PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEIT 1462

Query: 68   ------------RNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHK 115
                        R  T    + Q    SK H+ +S       +  DI T        +  
Sbjct: 1463 ISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS------EFVDDITTRREPYDSVEES 1516

Query: 116  EQKMALPMPTKRRSTFV-QSPADACTPPDTSSASEDEGSLRRQ-AALSAALQQSLQNAES 173
             +    P+P ++R T V  S +D     D+  + E+E  +R+Q   +SA    S    + 
Sbjct: 1517 SESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDE 1576

Query: 174  WINRSIQG-SSTSSSASSTLSHGEVKGTSG 202
            +I   ++  SS++ S     + G+ K T+G
Sbjct: 1577 FIRNQLKEISSSTESQKKEETKGKGKITAG 1606


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,720,456
Number of Sequences: 37866
Number of extensions: 2923584
Number of successful extensions: 10425
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 9761
Number of HSP's gapped (non-prelim): 619
length of query: 1576
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1460
effective length of database: 13,855,062
effective search space: 20228390520
effective search space used: 20228390520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.