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Search of human proteins with 55742693
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55742693 zyg-11 homolog B [Homo sapiens]
(744 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55742693 zyg-11 homolog B [Homo sapiens] 1483 0.0
gi|113408672 PREDICTED: zyg-11 homolog A [Homo sapiens] 873 0.0
gi|226437632 zyg-11 homolog A [Homo sapiens] 873 0.0
gi|169160755 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapi... 819 0.0
gi|88948888 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapiens] 819 0.0
gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens] 257 3e-68
gi|228008407 serine active site containing 1 [Homo sapiens] 37 0.051
gi|41281996 HEAT repeat containing 3 [Homo sapiens] 37 0.051
gi|4505047 lumican precursor [Homo sapiens] 37 0.067
gi|95113664 leucine rich repeat containing 1 [Homo sapiens] 37 0.067
gi|76563908 hypothetical protein LOC169436 [Homo sapiens] 36 0.15
gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens] 34 0.43
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 34 0.56
gi|151301204 unc-51-like kinase 4 [Homo sapiens] 33 0.74
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 33 0.96
gi|110825984 malignant fibrous histiocytoma amplified sequence 1... 33 0.96
gi|51339295 cation channel, sperm-associated, beta [Homo sapiens] 33 0.96
gi|254039600 F-box and leucine-rich repeat protein 17 [Homo sapi... 32 1.6
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 32 2.1
gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo s... 32 2.1
gi|189409124 armadillo repeat containing 3 [Homo sapiens] 32 2.8
gi|6005872 SEC63-like protein [Homo sapiens] 32 2.8
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 32 2.8
gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sa... 31 3.7
gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa... 31 3.7
gi|197333706 leucine rich repeat containing 8 family, member D [... 31 3.7
gi|34222199 leucine rich repeat containing 8 family, member D [H... 31 3.7
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 31 4.8
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 31 4.8
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 30 6.2
>gi|55742693 zyg-11 homolog B [Homo sapiens]
Length = 744
Score = 1483 bits (3838), Expect = 0.0
Identities = 744/744 (100%), Positives = 744/744 (100%)
Query: 1 MPEDQAGAAMEEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLR 60
MPEDQAGAAMEEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLR
Sbjct: 1 MPEDQAGAAMEEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLR 60
Query: 61 TMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADIT 120
TMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADIT
Sbjct: 61 TMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADIT 120
Query: 121 ITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLA 180
ITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLA
Sbjct: 121 ITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLA 180
Query: 181 EVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLN 240
EVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLN
Sbjct: 181 EVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLN 240
Query: 241 HLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLL 300
HLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLL
Sbjct: 241 HLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLL 300
Query: 301 ATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKP 360
ATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKP
Sbjct: 301 ATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKP 360
Query: 361 EILKLVVTGMRNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPN 420
EILKLVVTGMRNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPN
Sbjct: 361 EILKLVVTGMRNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPN 420
Query: 421 HQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLS 480
HQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLS
Sbjct: 421 HQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLS 480
Query: 481 TEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQG 540
TEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQG
Sbjct: 481 TEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQG 540
Query: 541 LELFMRVLESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSY 600
LELFMRVLESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSY
Sbjct: 541 LELFMRVLESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSY 600
Query: 601 FAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGC 660
FAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGC
Sbjct: 601 FAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGC 660
Query: 661 FTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILD 720
FTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILD
Sbjct: 661 FTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILD 720
Query: 721 SLEKHIVRHGRPPPCKKQPQARLN 744
SLEKHIVRHGRPPPCKKQPQARLN
Sbjct: 721 SLEKHIVRHGRPPPCKKQPQARLN 744
>gi|113408672 PREDICTED: zyg-11 homolog A [Homo sapiens]
Length = 759
Score = 873 bits (2255), Expect = 0.0
Identities = 455/729 (62%), Positives = 555/729 (76%), Gaps = 6/729 (0%)
Query: 11 EEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLND 70
EEASPY+L++ICLN L +LEK CS R DGTLCL E FPQEVA+R LR M + G L D
Sbjct: 31 EEASPYTLVNICLNVLIANLEKLCSERPDGTLCLPEHWSFPQEVAERFLRVMTWQGKLTD 90
Query: 71 GTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADITITDIISGLGS 130
T IFRGNQM+LK I+KAKIS AF KAFC HKL+EL+AT V+AD+ + DIISGL S
Sbjct: 91 RTASIFRGNQMKLKLVNIQKAKISTAAFIKAFCRHKLIELNATAVHADLPVPDIISGLCS 150
Query: 131 NKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLES 190
N+WIQQNLQCL+L+S ++ ++ FS+L+GLR LS+ NV F+ EDLA V+ LPRLES
Sbjct: 151 NRWIQQNLQCLLLDSTSIP-QNSRLLFFSQLTGLRILSVFNVCFHTEDLANVSQLPRLES 209
Query: 191 LDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQF 250
LDISNT +TDI+ALL CKDRLKSLTMH+LKCL MT +QIL V+RELK L HLDISD +Q
Sbjct: 210 LDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQILAVIRELKCLLHLDISDHRQL 269
Query: 251 TSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLLATDAGYSEFL 310
SD+A LL+QKDILPN+VSLD+SG +TD+AVE FI+ RP+MQFVGLLATDAG S+F
Sbjct: 270 KSDLAFHLLQQKDILPNVVSLDISGGNCITDEAVELFIRLRPAMQFVGLLATDAGSSDFF 329
Query: 311 TGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGM 370
T + L+V+G A+ +QI+EAL RY R+ FV+EAL LF+ T ME T P ILKLV GM
Sbjct: 330 TTKQGLRVAGGASMSQISEALSRYRNRSCFVKEALHRLFTETFSMEVTMPAILKLVAIGM 389
Query: 371 RNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLL 430
RNHP++L VQ ASAC NLT+Q LA GMPVRLL++VT LL KA+++FP++QQLQKNCLL
Sbjct: 390 RNHPLDLRVQFTASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLL 449
Query: 431 SLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTE 490
SL + RIL DVPF+RF+AAK VM+WLC HE+ MQ MAV++ SILA +LS EQTAQL
Sbjct: 450 SLTNSRILVDVPFDRFDAAKFVMRWLCKHENPKMQTMAVSVTSILALQLSPEQTAQLEEL 509
Query: 491 LFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLES 550
V++LL IVKQKT +N D T FTL ALWNLTD SP C+HFIENQGL++F++VLE+
Sbjct: 510 FMAVKELLAIVKQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 551 FPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLI 610
F +ES+IQ KVLGLLNNIAEV+EL S+L+ +D + HI+SLL S E+EVSYFAAGIIAHL
Sbjct: 570 F-SESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKHINSLLCSREMEVSYFAAGIIAHLT 628
Query: 611 SRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEM---VAYRSFNPFFPLLGCFTTPGVQ 667
S Q W QR +LL DLH+ I WP+ C+M V YRSF FFPLLG F+ P VQ
Sbjct: 629 S-DRQLWISRDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQ 687
Query: 668 LWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILDSLEKHIV 727
LWA+WAM HVCSKNPS+YC ML+EE GLQ L +I++H P QQIA +ILD H +
Sbjct: 688 LWALWAMYHVCSKNPSKYCKMLVEEEGLQLLCDIQEHSEATPKAQQIAASILDDFRMHFM 747
Query: 728 RHGRPPPCK 736
+ RP C+
Sbjct: 748 NYQRPTLCQ 756
>gi|226437632 zyg-11 homolog A [Homo sapiens]
Length = 759
Score = 873 bits (2255), Expect = 0.0
Identities = 455/729 (62%), Positives = 555/729 (76%), Gaps = 6/729 (0%)
Query: 11 EEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLND 70
EEASPY+L++ICLN L +LEK CS R DGTLCL E FPQEVA+R LR M + G L D
Sbjct: 31 EEASPYTLVNICLNVLIANLEKLCSERPDGTLCLPEHWSFPQEVAERFLRVMTWQGKLTD 90
Query: 71 GTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADITITDIISGLGS 130
T IFRGNQM+LK I+KAKIS AF KAFC HKL+EL+AT V+AD+ + DIISGL S
Sbjct: 91 RTASIFRGNQMKLKLVNIQKAKISTAAFIKAFCRHKLIELNATAVHADLPVPDIISGLCS 150
Query: 131 NKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLES 190
N+WIQQNLQCL+L+S ++ ++ FS+L+GLR LS+ NV F+ EDLA V+ LPRLES
Sbjct: 151 NRWIQQNLQCLLLDSTSIP-QNSRLLFFSQLTGLRILSVFNVCFHTEDLANVSQLPRLES 209
Query: 191 LDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQF 250
LDISNT +TDI+ALL CKDRLKSLTMH+LKCL MT +QIL V+RELK L HLDISD +Q
Sbjct: 210 LDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQILAVIRELKCLLHLDISDHRQL 269
Query: 251 TSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLLATDAGYSEFL 310
SD+A LL+QKDILPN+VSLD+SG +TD+AVE FI+ RP+MQFVGLLATDAG S+F
Sbjct: 270 KSDLAFHLLQQKDILPNVVSLDISGGNCITDEAVELFIRLRPAMQFVGLLATDAGSSDFF 329
Query: 311 TGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGM 370
T + L+V+G A+ +QI+EAL RY R+ FV+EAL LF+ T ME T P ILKLV GM
Sbjct: 330 TTKQGLRVAGGASMSQISEALSRYRNRSCFVKEALHRLFTETFSMEVTMPAILKLVAIGM 389
Query: 371 RNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLL 430
RNHP++L VQ ASAC NLT+Q LA GMPVRLL++VT LL KA+++FP++QQLQKNCLL
Sbjct: 390 RNHPLDLRVQFTASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLL 449
Query: 431 SLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTE 490
SL + RIL DVPF+RF+AAK VM+WLC HE+ MQ MAV++ SILA +LS EQTAQL
Sbjct: 450 SLTNSRILVDVPFDRFDAAKFVMRWLCKHENPKMQTMAVSVTSILALQLSPEQTAQLEEL 509
Query: 491 LFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLES 550
V++LL IVKQKT +N D T FTL ALWNLTD SP C+HFIENQGL++F++VLE+
Sbjct: 510 FMAVKELLAIVKQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 551 FPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLI 610
F +ES+IQ KVLGLLNNIAEV+EL S+L+ +D + HI+SLL S E+EVSYFAAGIIAHL
Sbjct: 570 F-SESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKHINSLLCSREMEVSYFAAGIIAHLT 628
Query: 611 SRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEM---VAYRSFNPFFPLLGCFTTPGVQ 667
S Q W QR +LL DLH+ I WP+ C+M V YRSF FFPLLG F+ P VQ
Sbjct: 629 S-DRQLWISRDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQ 687
Query: 668 LWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILDSLEKHIV 727
LWA+WAM HVCSKNPS+YC ML+EE GLQ L +I++H P QQIA +ILD H +
Sbjct: 688 LWALWAMYHVCSKNPSKYCKMLVEEEGLQLLCDIQEHSEATPKAQQIAASILDDFRMHFM 747
Query: 728 RHGRPPPCK 736
+ RP C+
Sbjct: 748 NYQRPTLCQ 756
>gi|169160755 PREDICTED: zyg-11 homolog A (C. elegans) [Homo
sapiens]
Length = 736
Score = 819 bits (2116), Expect = 0.0
Identities = 430/674 (63%), Positives = 520/674 (77%), Gaps = 6/674 (0%)
Query: 11 EEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLND 70
EEASPY+L++ICLN L +LEK CS R DGTLCL E FPQEVADR LR M + G L D
Sbjct: 31 EEASPYTLVNICLNVLIANLEKLCSERPDGTLCLPEHWSFPQEVADRFLRVMTWQGKLTD 90
Query: 71 GTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADITITDIISGLGS 130
T IFRGNQM+LK I+KAKIS AF KAFC HKL+EL+AT V+AD+ + DIISGL S
Sbjct: 91 RTASIFRGNQMKLKLVNIQKAKISTAAFIKAFCRHKLIELNATAVHADLPVPDIISGLCS 150
Query: 131 NKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLES 190
N+WIQQNLQCL+L+S ++ ++ FS+L+GLR LS+ NV F+ EDLA V+ LPRLES
Sbjct: 151 NRWIQQNLQCLLLDSTSIP-QNSRLLFFSQLTGLRILSVFNVCFHTEDLANVSQLPRLES 209
Query: 191 LDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQF 250
LDISNT +TDI+ALL CKDRLKSLTMH+LKCL MT +QIL V+RELK L HLDISD +Q
Sbjct: 210 LDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQILAVIRELKCLLHLDISDHRQL 269
Query: 251 TSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLLATDAGYSEFL 310
SD+A LL+QKDILPN+VSLD+SG +TD+AVE FI+ RP+MQFVGLLATDAG S+F
Sbjct: 270 KSDLAFHLLQQKDILPNVVSLDISGGNCITDEAVELFIRLRPAMQFVGLLATDAGSSDFF 329
Query: 311 TGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGM 370
T + L+V+G A+ +QI+EAL RY R+ FV+EAL LF+ T ME T P ILKLV GM
Sbjct: 330 TTKQGLRVAGGASMSQISEALSRYRNRSCFVKEALHRLFTETFSMEVTMPAILKLVAIGM 389
Query: 371 RNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLL 430
RNHP++L VQ ASAC NLT+Q LA GMPVRLL++VT LL KA+++FP++QQLQKNCLL
Sbjct: 390 RNHPLDLRVQFTASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLL 449
Query: 431 SLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTE 490
SL + RIL DVPF+RF+AAK VM+WLC HE+ MQ MAV++ SILA +LS EQTAQL
Sbjct: 450 SLTNSRILVDVPFDRFDAAKFVMRWLCKHENPKMQTMAVSVTSILALQLSPEQTAQLEEL 509
Query: 491 LFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLES 550
V++LL IVKQKT +N D T FTL ALWNLTD SP C+HFIENQGL++F++VLE+
Sbjct: 510 FMAVKELLAIVKQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 551 FPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLI 610
F +ES+IQ KVLGLLNNIAEV+EL S+L+ +D + HI+SLL S E+EVSYFAAGIIAHL
Sbjct: 570 F-SESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKHINSLLCSREMEVSYFAAGIIAHLT 628
Query: 611 SRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEM---VAYRSFNPFFPLLGCFTTPGVQ 667
S Q W QR +LL DLH+ I WP+ C+M V YRSF FFPLLG F+ P VQ
Sbjct: 629 S-DRQLWISRDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQ 687
Query: 668 LWAVWAMQHVCSKN 681
LWA+WAM HVCSKN
Sbjct: 688 LWALWAMYHVCSKN 701
>gi|88948888 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapiens]
Length = 736
Score = 819 bits (2116), Expect = 0.0
Identities = 430/674 (63%), Positives = 520/674 (77%), Gaps = 6/674 (0%)
Query: 11 EEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLND 70
EEASPY+L++ICLN L +LEK CS R DGTLCL E FPQEVADR LR M + G L D
Sbjct: 31 EEASPYTLVNICLNVLIANLEKLCSERPDGTLCLPEHWSFPQEVADRFLRVMTWQGKLTD 90
Query: 71 GTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADITITDIISGLGS 130
T IFRGNQM+LK I+KAKIS AF KAFC HKL+EL+AT V+AD+ + DIISGL S
Sbjct: 91 RTASIFRGNQMKLKLVNIQKAKISTAAFIKAFCRHKLIELNATAVHADLPVPDIISGLCS 150
Query: 131 NKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLES 190
N+WIQQNLQCL+L+S ++ ++ FS+L+GLR LS+ NV F+ EDLA V+ LPRLES
Sbjct: 151 NRWIQQNLQCLLLDSTSIP-QNSRLLFFSQLTGLRILSVFNVCFHTEDLANVSQLPRLES 209
Query: 191 LDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQF 250
LDISNT +TDI+ALL CKDRLKSLTMH+LKCL MT +QIL V+RELK L HLDISD +Q
Sbjct: 210 LDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQILAVIRELKCLLHLDISDHRQL 269
Query: 251 TSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLLATDAGYSEFL 310
SD+A LL+QKDILPN+VSLD+SG +TD+AVE FI+ RP+MQFVGLLATDAG S+F
Sbjct: 270 KSDLAFHLLQQKDILPNVVSLDISGGNCITDEAVELFIRLRPAMQFVGLLATDAGSSDFF 329
Query: 311 TGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGM 370
T + L+V+G A+ +QI+EAL RY R+ FV+EAL LF+ T ME T P ILKLV GM
Sbjct: 330 TTKQGLRVAGGASMSQISEALSRYRNRSCFVKEALHRLFTETFSMEVTMPAILKLVAIGM 389
Query: 371 RNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLL 430
RNHP++L VQ ASAC NLT+Q LA GMPVRLL++VT LL KA+++FP++QQLQKNCLL
Sbjct: 390 RNHPLDLRVQFTASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLL 449
Query: 431 SLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTE 490
SL + RIL DVPF+RF+AAK VM+WLC HE+ MQ MAV++ SILA +LS EQTAQL
Sbjct: 450 SLTNSRILVDVPFDRFDAAKFVMRWLCKHENPKMQTMAVSVTSILALQLSPEQTAQLEEL 509
Query: 491 LFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLES 550
V++LL IVKQKT +N D T FTL ALWNLTD SP C+HFIENQGL++F++VLE+
Sbjct: 510 FMAVKELLAIVKQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 551 FPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLI 610
F +ES+IQ KVLGLLNNIAEV+EL S+L+ +D + HI+SLL S E+EVSYFAAGIIAHL
Sbjct: 570 F-SESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKHINSLLCSREMEVSYFAAGIIAHLT 628
Query: 611 SRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEM---VAYRSFNPFFPLLGCFTTPGVQ 667
S Q W QR +LL DLH+ I WP+ C+M V YRSF FFPLLG F+ P VQ
Sbjct: 629 S-DRQLWISRDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQ 687
Query: 668 LWAVWAMQHVCSKN 681
LWA+WAM HVCSKN
Sbjct: 688 LWALWAMYHVCSKN 701
>gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]
Length = 766
Score = 257 bits (656), Expect = 3e-68
Identities = 211/755 (27%), Positives = 358/755 (47%), Gaps = 85/755 (11%)
Query: 10 MEEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVF-PQEVADRLLRTM------ 62
M +P SL+ +C +F +L+ D P +F P E+ DRL+
Sbjct: 1 MASDTPESLMALCTDFCLRNLDGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNA 60
Query: 63 --------AFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATG 114
+F L +D R ++ L+ ++ + A+ RK LVEL T
Sbjct: 61 ACNFEPHESFFSLFSDPRST--RLTRIHLREDLVQDQDLEAI--RK----QDLVELYLT- 111
Query: 115 VNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDP-----------------YERC 157
N + + L S +L ++ E+P +
Sbjct: 112 -NCEKLSAKSLQTLRSFSHTLVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFT 170
Query: 158 FSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMH 217
F S LR L++ ++ + + + L L +LD+S +D L KD L SL ++
Sbjct: 171 FEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLY 230
Query: 218 HLKCLKMTTTQILDVVRELKHLNHLDISDDK-------QFTSDIALRLLEQKDILPNLVS 270
++ + + V+ +L L HLDIS D+ + T ++ L L QK L NL+S
Sbjct: 231 NMDL----SDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTREV-LSLFVQK--LGNLMS 283
Query: 271 LDVSGR--------KHVTDKAVEAFIQQRPS-----------MQFVGLLATDAGYSEFLT 311
LD+SG + ++A + I+ S +QF+GL LT
Sbjct: 284 LDISGHMILENCSISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFENSLCR---LT 340
Query: 312 GEGHLKVSGEANETQIAEALKRYSE-RAFFVREALFHLFSLTHVMEKTKP-EILKLVVTG 369
KVSG+ NE Q+ A++ Y+E R A+ LF + + + LKLV+T
Sbjct: 341 HIPAYKVSGDKNEEQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITA 400
Query: 370 MRNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCL 429
++ H + +Q+ SA +F LT + + V+L V ++L ME + +Q+NC
Sbjct: 401 LKCHKYDRNIQVTGSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESY-QEVTVQRNCC 459
Query: 430 LSLCSDRILQDVPFNRFEAAKLVMQWLC-NHEDQNMQRMAVAIISILAAKLSTEQTAQLG 488
L+LC+ I +++ F +L++ L +D+++QR+AV + + L ++ + +G
Sbjct: 460 LTLCNFSIPEELEFQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVG 519
Query: 489 TELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVL 548
F+V +L+++++K + D ++F+ SALWN+TDE+P C F+ G++LF+ L
Sbjct: 520 KMGFVVT-MLKLIQKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCL 578
Query: 549 ESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVE--VEVSYFAAGII 606
+ FP + + + +LGLL N+AEV+EL +LM FI S+LL S +EVSY A G++
Sbjct: 579 KEFPEKQELHRNMLGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVL 638
Query: 607 AHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGV 666
+H++ G +AW + QR + + + +AI W + YRSF P LL +P
Sbjct: 639 SHIMFDGPEAWGVCEPQREEVEERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVS 698
Query: 667 QLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNI 701
Q WA WA+ ++ S P +YC +LI+EGG+ L +I
Sbjct: 699 QHWATWALYNLVSVYPDKYCPLLIKEGGMPLLRDI 733
>gi|228008407 serine active site containing 1 [Homo sapiens]
Length = 654
Score = 37.4 bits (85), Expect = 0.051
Identities = 21/83 (25%), Positives = 41/83 (49%)
Query: 527 ESPTTCRHFIENQGLELFMRVLESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDH 586
E T C N GL+L R+ +Q+ ++ ++ N+A + LHS ++ ++
Sbjct: 284 EISTHCDKIEANGGLQLLQRLYRLHKDCPKVQRNIMRVIGNMALNEHLHSSIVRSGWVSI 343
Query: 587 ISSLLHSVEVEVSYFAAGIIAHL 609
++ + S + S AA I+A+L
Sbjct: 344 MAEAMKSPHIMESSHAARILANL 366
>gi|41281996 HEAT repeat containing 3 [Homo sapiens]
Length = 680
Score = 37.4 bits (85), Expect = 0.051
Identities = 19/69 (27%), Positives = 33/69 (47%)
Query: 502 KQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTESSIQQKV 561
K+ N+NS++ T++ LWN+ + S F + LE+ ++ L FPT + V
Sbjct: 148 KKDQNRNSIENIANETVNVLWNICECSSRAVSIFNKEGCLEIVLKYLSRFPTNVDLAISV 207
Query: 562 LGLLNNIAE 570
L + E
Sbjct: 208 AYCLQTVTE 216
>gi|4505047 lumican precursor [Homo sapiens]
Length = 338
Score = 37.0 bits (84), Expect = 0.067
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 9/110 (8%)
Query: 137 NLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPR-LESLDISN 195
+LQ L+L+ L R FS+L L+ L I +N V LP+ LE L +++
Sbjct: 91 DLQWLILDHNLLENSKIKGRVFSKLKQLKKLHIN----HNNLTESVGPLPKSLEDLQLTH 146
Query: 196 TSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDIS 245
IT + + + L +LT HL+ ++ + + LK L +LD+S
Sbjct: 147 NKITKLGSF----EGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLS 192
>gi|95113664 leucine rich repeat containing 1 [Homo sapiens]
Length = 524
Score = 37.0 bits (84), Expect = 0.067
Identities = 41/143 (28%), Positives = 66/143 (46%), Gaps = 23/143 (16%)
Query: 136 QNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSIT-NVLFYNEDLAEVASLPRLESLDIS 194
QNL CL +N ++L L L +L + N+L Y D + L RLE LD+
Sbjct: 128 QNLTCLSVNDISLQ---SLPENIGNLYNLASLELRENLLTYLPD--SLTQLRRLEELDLG 182
Query: 195 NTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRE---LKHLNHLDISDDKQFT 251
N I ++ + + HLK L + Q+ ++ +E LK+L LD+S+++
Sbjct: 183 NNEIYNLPESIG--------ALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENR--- 231
Query: 252 SDIALRLLEQKDILPNLVSLDVS 274
RL E+ L +L L +S
Sbjct: 232 ---LERLPEEISGLTSLTDLVIS 251
>gi|76563908 hypothetical protein LOC169436 [Homo sapiens]
Length = 680
Score = 35.8 bits (81), Expect = 0.15
Identities = 56/251 (22%), Positives = 99/251 (39%), Gaps = 38/251 (15%)
Query: 189 ESLDISNTSITDITAL-------LACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNH 241
E+L+ S + +DI +L +C + MH K L+ + + V LK +
Sbjct: 205 EALNFSFSQKSDIWSLGCIILDMTSCSFMDGTEAMHLRKSLRQSPGSLKAV---LKTMEE 261
Query: 242 LDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLLA 301
I D + F +++LP ++ +D S R + D F++ V L
Sbjct: 262 KQIPDVETF-----------RNLLPLMLQIDPSDRITIKDVVHITFLRGSFKSSCVSLTL 310
Query: 302 ----TDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLT--HVM 355
A ++ L E N I E ++++S A+ L + +
Sbjct: 311 HRQMVPASITDMLL---------EGNVASILEVMQKFSGWPEVQLRAMKRLLKMPADQLG 361
Query: 356 EKTKPEILKLVVTGMRNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLAD--VTHLLLK 413
PE++++VVT M H L VQL A + + +L Q L + + +T LL
Sbjct: 362 LPWPPELVEVVVTTMELHDRVLDVQLCACSLLLHLLGQALVHHPEAKAPCNQAITSTLLS 421
Query: 414 AMEHFPNHQQL 424
A++ P + L
Sbjct: 422 ALQSHPEEEPL 432
>gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens]
Length = 493
Score = 34.3 bits (77), Expect = 0.43
Identities = 34/143 (23%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 460 EDQNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQ--------LLQIVKQKTNQNSVD 511
ED ++ +A ++ L+ L+ +G ++ + + LLQ QK
Sbjct: 300 EDAGLELLACPVLRCLSNLLTEAAVETVGGQMQLRDERVVAALFILLQFFFQKQ-----P 354
Query: 512 TTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTESSIQQKVLGLLNNIAEV 571
+ L L L NLT SP+ C + L+L +L+ P + + VL +L N+AE
Sbjct: 355 SLLPEGLWLLNNLTANSPSFCTSLLS---LDLIEPLLQLLPVSNVVSVMVLTVLCNVAEK 411
Query: 572 QELHSELMWKDFIDHISSLLHSV 594
+ + +W + + +LLH++
Sbjct: 412 GPAYCQRLWPGPL--LPALLHTL 432
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 33.9 bits (76), Expect = 0.56
Identities = 32/137 (23%), Positives = 64/137 (46%), Gaps = 13/137 (9%)
Query: 138 LQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTS 197
L+ L LN + E P + + L +L++T + LP L+ LD+S
Sbjct: 307 LRTLTLNGASQITEFPD---LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNL 363
Query: 198 ITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALR 257
+ D+ + C+ +L+ + + H + ++ +D ++L L L+++ +K IA+
Sbjct: 364 LEDLPSFSVCQ-KLQKIDLRHNEIYEIK----VDTFQQLLSLRSLNLAWNK-----IAII 413
Query: 258 LLEQKDILPNLVSLDVS 274
LP+L+ LD+S
Sbjct: 414 HPNAFSTLPSLIKLDLS 430
>gi|151301204 unc-51-like kinase 4 [Homo sapiens]
Length = 1275
Score = 33.5 bits (75), Expect = 0.74
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 9/178 (5%)
Query: 448 AAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQ 507
A ++M+ L E++ + MA II + S + FI ++ I+
Sbjct: 605 AYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQSQG------FITGEIGPILWYLFRH 658
Query: 508 NSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTESSIQQKVLGLLNN 567
++ D+ +SAL +T SPT ++ IE GL + L S +QQ +L L
Sbjct: 659 STADSLRITAVSALCRITRHSPTAFQNVIEKVGLNSVINSLAS--AICKVQQYMLTLFAA 716
Query: 568 IAEVQ-ELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQR 624
+ L + K F+ I LL S + A ++ +++ + LS R
Sbjct: 717 MLSCGIHLQRLIQEKGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREMLLLSCQAR 774
Score = 30.4 bits (67), Expect = 6.2
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 511 DTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTE--SSIQQKVLGLLNNI 568
D + L L +T+ +PT R E++ + L V + Q V+ LL+N+
Sbjct: 1002 DPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIFEVTLEHQESILGNTMQSVIALLSNL 1061
Query: 569 AEVQELHSELMWKD-FIDHISSLL 591
++ + EL+++ + HI +LL
Sbjct: 1062 VACKDSNMELLYEQGLVSHICNLL 1085
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 33.1 bits (74), Expect = 0.96
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 13/109 (11%)
Query: 151 EDPYERCFSRLSGLRALSITNVLFYNEDLAEVA--SLPRLESLDISNTSITDITAL---- 204
E PY SRLSGLR L++ N L +E L + A SL +L+ L +++ I+ +
Sbjct: 86 ELPYNE-LSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGA 144
Query: 205 LACKDRLKSLTMHHLKCLKMTTTQILDVV--RELKHLNHLDISDDKQFT 251
L+ + +L+ L + H T LD +L L +LD+S ++ T
Sbjct: 145 LSRQTQLRELYLQH----NQLTDSGLDATTFSKLHSLEYLDLSHNQLTT 189
>gi|110825984 malignant fibrous histiocytoma amplified sequence 1
[Homo sapiens]
Length = 1052
Score = 33.1 bits (74), Expect = 0.96
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 180 AEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHL 239
A++ +L LE LD+S + + L+C RL++L + H + L Q+L +V L
Sbjct: 152 AQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQ-LTAFPRQLLQLVA----L 206
Query: 240 NHLDISDDK 248
LD+S ++
Sbjct: 207 EELDVSSNR 215
>gi|51339295 cation channel, sperm-associated, beta [Homo sapiens]
Length = 1116
Score = 33.1 bits (74), Expect = 0.96
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 191 LDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQF 250
+DI +IT T + A ++ L +T+HH + T +LDV+RE Q+
Sbjct: 112 VDIPRENITQSTDIAAVEEWLVRITLHHGLNIYATEGTLLDVIRE----------PILQW 161
Query: 251 TSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFI 288
T + E + P++V L V+ D A+ FI
Sbjct: 162 TPGDVIPESEISKLYPHVVDLKVTKCPCANDVALLGFI 199
>gi|254039600 F-box and leucine-rich repeat protein 17 [Homo
sapiens]
Length = 303
Score = 32.3 bits (72), Expect = 1.6
Identities = 28/129 (21%), Positives = 63/129 (48%), Gaps = 5/129 (3%)
Query: 176 NEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVV-R 234
++ + + L L SLD+ + + D ++ R K+L+ +L + + ++V+ +
Sbjct: 132 SKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAK 191
Query: 235 ELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSM 294
E ++L L + K +D AL + + + + ++DV K +TD+ Q S+
Sbjct: 192 EGQNLKELYLVSCK--ITDYALIAIGRYSM--TIETVDVGWCKEITDQGATLIAQSSKSL 247
Query: 295 QFVGLLATD 303
+++GL+ D
Sbjct: 248 RYLGLMRCD 256
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 32.0 bits (71), Expect = 2.1
Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 38/168 (22%)
Query: 159 SRLSGLRALSITNVLFYNEDLAEVASLPRLESLD------ISNTSITDITALLACK---- 208
+RL GL+ L + + +S P L +LD I + I D+ A K
Sbjct: 974 NRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPADKPGQD 1033
Query: 209 --DRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIA----------- 255
+L+++T L L +T + ++R + L+ LD+S T +
Sbjct: 1034 NRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTR 1093
Query: 256 -----------LRLLEQKDI----LPNLVSLDVSGRKHVTDKAVEAFI 288
+L +Q I + N+ +D+ G K +T KA E FI
Sbjct: 1094 YSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITRKACEHFI 1141
>gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo
sapiens]
Length = 2273
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 486 QLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFM 545
QLG E +L + + ++ D F ++N+TD + ++E L+ F
Sbjct: 467 QLGEEGITAEAILNFLYKGPRESQADDMANFDWRDIFNITDRTLRLVNQYLECLVLDKF- 525
Query: 546 RVLESFPTESSIQQKVLGLL 565
ES+ E+ + Q+ L LL
Sbjct: 526 ---ESYNDETQLTQRALSLL 542
>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
Length = 872
Score = 31.6 bits (70), Expect = 2.8
Identities = 45/176 (25%), Positives = 80/176 (45%), Gaps = 13/176 (7%)
Query: 456 LCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLK 515
L HED+ ++R A I ILA S +L EL ++ ++ Q + V +
Sbjct: 75 LLTHEDKIVRRNATMIFGILA---SNNDVKKLLRELDVMN---SVIAQLAPEEEV-VIHE 127
Query: 516 FTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTESSIQQKVLGLLNNIAEVQELH 575
F L N++ E + + F E+ GLE +R+L S + +++ + + N+ + +
Sbjct: 128 FASLCLANMSAEYTSKVQIF-EHGGLEPLIRLLSS--PDPDVKKNSMECIYNLVQDFQCR 184
Query: 576 SELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQRNSLLDDL 631
++L + I I LL S E V A +I+ +++ T+ R N LD L
Sbjct: 185 AKLQELNAIPPILDLLKS-EYPVIQLLALKTLGVIANDKESRTMLRD--NQGLDHL 237
>gi|6005872 SEC63-like protein [Homo sapiens]
Length = 760
Score = 31.6 bits (70), Expect = 2.8
Identities = 43/177 (24%), Positives = 68/177 (38%), Gaps = 13/177 (7%)
Query: 380 QLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQ 439
QL NL K + P L A V L A P + + +L C +LQ
Sbjct: 276 QLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCP-ALLQ 334
Query: 440 DVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQ 499
E ++ Q + ++ + ++ L + Q A G + F LLQ
Sbjct: 335 -------EMVNVICQLIVMARNREEREFRAPTLASLENCMKLSQMAVQGLQQF-KSPLLQ 386
Query: 500 IVK-QKTNQNSVDTTLKF---TLSALWNLTDESPTTCRHFIENQGLELFMRVLESFP 552
+ ++ N V K+ T+ L +L + T HF+E++ E M VL SFP
Sbjct: 387 LPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFP 443
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 31.6 bits (70), Expect = 2.8
Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 8/170 (4%)
Query: 117 ADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYN 176
+D+ I + I +K + ++ + L T++ + E ++ G+ L ++ +
Sbjct: 177 SDLDICEFIDNYALSK---KGVKAMSLKRSTIT-DAGLEVMLEQMQGVVRLELSGCNDFT 232
Query: 177 EDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVREL 236
E + R+ SL +S+ A+ A L +L L+ +T T +
Sbjct: 233 EAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQ 292
Query: 237 KHLNH-LDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVE 285
H H L + + T+ + ++ LPNL +L +SG VTD VE
Sbjct: 293 GHSTHTLRLLSCWEITNHGVVNVVHS---LPNLTALSLSGCSKVTDDGVE 339
>gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo
sapiens]
Length = 2316
Score = 31.2 bits (69), Expect = 3.7
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 28/202 (13%)
Query: 104 HHKLVELDATGVNADI-----TITDIISGLGS----NKWIQQNLQCLVLNSLTLSLEDPY 154
+H L L ATG ++I D+ +G G+ NK + ++ Q L+++ D
Sbjct: 324 NHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKI 383
Query: 155 ERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSL 214
S + G ++ N+D +A P ES+ SN SI CK
Sbjct: 384 HITRSHIMGAETHIVSQTC--NQDARILAMTP--ESI-YSNPSIQ------GCK------ 426
Query: 215 TMHHLKCLK-MTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDV 273
T+ + C M T+ L +RE K+L D + K + + A+ L +K I ++D+
Sbjct: 427 TVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSGEENMDI 486
Query: 274 SGRKHVTDKAVEAFIQQRPSMQ 295
+ + H + F Q + ++Q
Sbjct: 487 T-KSHTVAIDNQIFKQDQSNVQ 507
>gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo
sapiens]
Length = 2342
Score = 31.2 bits (69), Expect = 3.7
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 28/202 (13%)
Query: 104 HHKLVELDATGVNADI-----TITDIISGLGS----NKWIQQNLQCLVLNSLTLSLEDPY 154
+H L L ATG ++I D+ +G G+ NK + ++ Q L+++ D
Sbjct: 350 NHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKI 409
Query: 155 ERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSL 214
S + G ++ N+D +A P ES+ SN SI CK
Sbjct: 410 HITRSHIMGAETHIVSQTC--NQDARILAMTP--ESI-YSNPSIQ------GCK------ 452
Query: 215 TMHHLKCLK-MTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDV 273
T+ + C M T+ L +RE K+L D + K + + A+ L +K I ++D+
Sbjct: 453 TVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSGEENMDI 512
Query: 274 SGRKHVTDKAVEAFIQQRPSMQ 295
+ + H + F Q + ++Q
Sbjct: 513 T-KSHTVAIDNQIFKQDQSNVQ 533
>gi|197333706 leucine rich repeat containing 8 family, member D
[Homo sapiens]
Length = 858
Score = 31.2 bits (69), Expect = 3.7
Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 25/174 (14%)
Query: 104 HHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSG 163
H K++ + + ITD+ L + LVLNSL ++
Sbjct: 589 HLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLNSL------------KKMMN 636
Query: 164 LRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLK 223
+ L + N A + SL L+ LD+ + +I I +++ + LK LT CLK
Sbjct: 637 VAELELQNCELERIPHA-IFSLSNLQELDLKSNNIRTIEEIISFQ-HLKRLT-----CLK 689
Query: 224 MTTTQILDV---VRELKHLNHLDISDDKQFTSDIA---LRLLEQKDILPNLVSL 271
+ +I+ + + +K+L L S++K + +A L+ L D+ N +S+
Sbjct: 690 LWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISM 743
>gi|34222199 leucine rich repeat containing 8 family, member D [Homo
sapiens]
Length = 858
Score = 31.2 bits (69), Expect = 3.7
Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 25/174 (14%)
Query: 104 HHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSG 163
H K++ + + ITD+ L + LVLNSL ++
Sbjct: 589 HLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLNSL------------KKMMN 636
Query: 164 LRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLK 223
+ L + N A + SL L+ LD+ + +I I +++ + LK LT CLK
Sbjct: 637 VAELELQNCELERIPHA-IFSLSNLQELDLKSNNIRTIEEIISFQ-HLKRLT-----CLK 689
Query: 224 MTTTQILDV---VRELKHLNHLDISDDKQFTSDIA---LRLLEQKDILPNLVSL 271
+ +I+ + + +K+L L S++K + +A L+ L D+ N +S+
Sbjct: 690 LWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISM 743
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 30.8 bits (68), Expect = 4.8
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Query: 139 QCLVLNSLTLS---LEDPYERCFSRLSGLRALSITNVLFYNEDLAE--VASLPRLESLDI 193
QC L +L+L L DP ++ S L L+++ ++E + ++S RL+ L++
Sbjct: 204 QCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNL 263
Query: 194 SNT-SITDITALLACKDRLKSLTMHHLKCLK--MTTTQILDVVRELKHLNHLDISDDKQF 250
S T+ +A +++T +L + + + + +VR +L HLD+SD
Sbjct: 264 SWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVML 323
Query: 251 TSD 253
+D
Sbjct: 324 KND 326
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 30.8 bits (68), Expect = 4.8
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Query: 139 QCLVLNSLTLS---LEDPYERCFSRLSGLRALSITNVLFYNEDLAE--VASLPRLESLDI 193
QC L +L+L L DP ++ S L L+++ ++E + ++S RL+ L++
Sbjct: 204 QCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNL 263
Query: 194 SNT-SITDITALLACKDRLKSLTMHHLKCLK--MTTTQILDVVRELKHLNHLDISDDKQF 250
S T+ +A +++T +L + + + + +VR +L HLD+SD
Sbjct: 264 SWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVML 323
Query: 251 TSD 253
+D
Sbjct: 324 KND 326
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 30.4 bits (67), Expect = 6.2
Identities = 44/184 (23%), Positives = 81/184 (44%), Gaps = 21/184 (11%)
Query: 83 LKRACIRKAKISAVAFRKAFCHHKLVELDA---TGVNADITITDIISGLGSNKWIQQNLQ 139
L C +K KI + FR K+V LD VN + I++ +NLQ
Sbjct: 177 LLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK-WVLPILTQFTPYLGHMRNLQ 235
Query: 140 CLVLNSLTLS----------LEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPR-- 187
LVL+ + +S + + F +L L+ LS+ +V F L ++ S +
Sbjct: 236 KLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTS 295
Query: 188 LESLDISNTSI--TDITALLACK--DRLKSLTMHHLKCLKMTTTQILDVVREL-KHLNHL 242
L+ L I+N + +D+ L C +LK+L + ++ + + ++ ++ L +L
Sbjct: 296 LKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYL 355
Query: 243 DISD 246
D+ D
Sbjct: 356 DLDD 359
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,759,362
Number of Sequences: 37866
Number of extensions: 1111415
Number of successful extensions: 2651
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2607
Number of HSP's gapped (non-prelim): 47
length of query: 744
length of database: 18,247,518
effective HSP length: 110
effective length of query: 634
effective length of database: 14,082,258
effective search space: 8928151572
effective search space used: 8928151572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.