Guide to the Human Genome
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Search of human proteins with 55741447

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55741447 pleckstrin homology domain containing, family H
(with MyTH4 domain) member 1 [Homo sapiens]
         (1364 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55741447 pleckstrin homology domain containing, family H (wit...  2748   0.0  
gi|217416392 pleckstrin homology domain containing, family H (wi...  1174   0.0  
gi|154354979 myosin X [Homo sapiens]                                  113   1e-24
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                      85   4e-16
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                      85   5e-16
gi|40255047 pleckstrin homology domain containing, family H (wit...    78   5e-14
gi|122937512 myosin VIIB [Homo sapiens]                                72   3e-12
gi|154146216 pleckstrin homology domain containing, family A (ph...    61   6e-09
gi|118402590 myosin XV [Homo sapiens]                                  59   2e-08
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit...    59   2e-08
gi|50234893 pleckstrin homology domain containing, family A (pho...    57   9e-08
gi|31377720 pleckstrin homology domain containing, family A (pho...    57   9e-08
gi|4505531 oxysterol binding protein [Homo sapiens]                    54   8e-07
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             54   8e-07
gi|93102364 SWAP-70 protein [Homo sapiens]                             54   1e-06
gi|187608516 centaurin, beta 2 [Homo sapiens]                          54   1e-06
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa...    54   1e-06
gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa...    54   1e-06
gi|7661880 centaurin beta1 [Homo sapiens]                              54   1e-06
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]                54   1e-06
gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ...    52   3e-06
gi|110349763 cytohesin 1 isoform 2 [Homo sapiens]                      52   3e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    52   4e-06
gi|195972859 cytohesin 2 isoform 2 [Homo sapiens]                      52   4e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     51   7e-06
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma...    51   7e-06
gi|4758968 cytohesin 3 [Homo sapiens]                                  51   7e-06
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...    51   7e-06
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...    51   7e-06
gi|58331179 KIAA1688 protein [Homo sapiens]                            51   9e-06

>gi|55741447 pleckstrin homology domain containing, family H (with
            MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 2748 bits (7123), Expect = 0.0
 Identities = 1364/1364 (100%), Positives = 1364/1364 (100%)

Query: 1    MAELKVEAPASVDWQKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENA 60
            MAELKVEAPASVDWQKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENA
Sbjct: 1    MAELKVEAPASVDWQKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENA 60

Query: 61   ETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEE 120
            ETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEE
Sbjct: 61   ETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEE 120

Query: 121  AKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALEAIQIAPSRKLLV 180
            AKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALEAIQIAPSRKLLV
Sbjct: 121  AKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALEAIQIAPSRKLLV 180

Query: 181  PPYGAAEQDSVPSEPGIQPMGQDSGSQAQGLKAAVLAPSPGALQSKDSVSEAASPLEDSS 240
            PPYGAAEQDSVPSEPGIQPMGQDSGSQAQGLKAAVLAPSPGALQSKDSVSEAASPLEDSS
Sbjct: 181  PPYGAAEQDSVPSEPGIQPMGQDSGSQAQGLKAAVLAPSPGALQSKDSVSEAASPLEDSS 240

Query: 241  SSTVHSGETVEAKPLQPHLGRESPPHQPCMKLLTFRCSSASWGEGLVTAQRGMLPGTKTS 300
            SSTVHSGETVEAKPLQPHLGRESPPHQPCMKLLTFRCSSASWGEGLVTAQRGMLPGTKTS
Sbjct: 241  SSTVHSGETVEAKPLQPHLGRESPPHQPCMKLLTFRCSSASWGEGLVTAQRGMLPGTKTS 300

Query: 301  AREGGPGSSLTLPKVRAPGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSG 360
            AREGGPGSSLTLPKVRAPGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSG
Sbjct: 301  AREGGPGSSLTLPKVRAPGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSG 360

Query: 361  LPELESRARSREEPEKMEMEEPPPAGKNEERESPKALGAELEEVELGNKPPTPPLHQFSS 420
            LPELESRARSREEPEKMEMEEPPPAGKNEERESPKALGAELEEVELGNKPPTPPLHQFSS
Sbjct: 361  LPELESRARSREEPEKMEMEEPPPAGKNEERESPKALGAELEEVELGNKPPTPPLHQFSS 420

Query: 421  WESRIYAVATSGMRLSDMSPRSNTACCASSPPALVSPGSFSGLVYKNVTVPVYTALKGRA 480
            WESRIYAVATSGMRLSDMSPRSNTACCASSPPALVSPGSFSGLVYKNVTVPVYTALKGRA
Sbjct: 421  WESRIYAVATSGMRLSDMSPRSNTACCASSPPALVSPGSFSGLVYKNVTVPVYTALKGRA 480

Query: 481  TQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSEGD 540
            TQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSEGD
Sbjct: 481  TQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSEGD 540

Query: 541  YAIPPDACSLDSDYSEPEHKLQRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRRWF 600
            YAIPPDACSLDSDYSEPEHKLQRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRRWF
Sbjct: 541  YAIPPDACSLDSDYSEPEHKLQRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRRWF 600

Query: 601  VLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLL 660
            VLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLL
Sbjct: 601  VLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLL 660

Query: 661  EEWIRVLQSLLKVQATGPPALLRGGTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYRSH 720
            EEWIRVLQSLLKVQATGPPALLRGGTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYRSH
Sbjct: 661  EEWIRVLQSLLKVQATGPPALLRGGTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYRSH 720

Query: 721  EDKRPLGCLPVRDAHIEEVDRSCDSDEDYEAGGTRRLLSSHCTLVIHPTEHSPTYLLIGT 780
            EDKRPLGCLPVRDAHIEEVDRSCDSDEDYEAGGTRRLLSSHCTLVIHPTEHSPTYLLIGT
Sbjct: 721  EDKRPLGCLPVRDAHIEEVDRSCDSDEDYEAGGTRRLLSSHCTLVIHPTEHSPTYLLIGT 780

Query: 781  KHEKDTWLYHLTVAAGGSSAKVGTAYEQLIGKLMDGEGDPDSPLWRHPMLCYSKDGLYAS 840
            KHEKDTWLYHLTVAAGGSSAKVGTAYEQLIGKLMDGEGDPDSPLWRHPMLCYSKDGLYAS
Sbjct: 781  KHEKDTWLYHLTVAAGGSSAKVGTAYEQLIGKLMDGEGDPDSPLWRHPMLCYSKDGLYAS 840

Query: 841  LTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQ 900
            LTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQ
Sbjct: 841  LTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQ 900

Query: 901  LMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPRSETGQYATYC 960
            LMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPRSETGQYATYC
Sbjct: 901  LMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPRSETGQYATYC 960

Query: 961  QRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSSTVD 1020
            QRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSSTVD
Sbjct: 961  QRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSSTVD 1020

Query: 1021 EFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGK 1080
            EFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGK
Sbjct: 1021 EFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGK 1080

Query: 1081 SEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELALEMAALM 1140
            SEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELALEMAALM
Sbjct: 1081 SEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELALEMAALM 1140

Query: 1141 AQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHGAPAEQLRHLADMLTTKW 1200
            AQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHGAPAEQLRHLADMLTTKW
Sbjct: 1141 AQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHGAPAEQLRHLADMLTTKW 1200

Query: 1201 ATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQLSSKENALVWIAVNEDGVSILDHN 1260
            ATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQLSSKENALVWIAVNEDGVSILDHN
Sbjct: 1201 ATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQLSSKENALVWIAVNEDGVSILDHN 1260

Query: 1261 TMQVHITYPYSSVTTFGGCRDDFMLVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMA 1320
            TMQVHITYPYSSVTTFGGCRDDFMLVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMA
Sbjct: 1261 TMQVHITYPYSSVTTFGGCRDDFMLVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMA 1320

Query: 1321 SYMNHCTTTVNPPTNPPGACQLWELDGRQFFSSVSCATKGPTLL 1364
            SYMNHCTTTVNPPTNPPGACQLWELDGRQFFSSVSCATKGPTLL
Sbjct: 1321 SYMNHCTTTVNPPTNPPGACQLWELDGRQFFSSVSCATKGPTLL 1364


>gi|217416392 pleckstrin homology domain containing, family H (with
            MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 1174 bits (3038), Expect = 0.0
 Identities = 609/1080 (56%), Positives = 780/1080 (72%), Gaps = 39/1080 (3%)

Query: 306  PGSSLTLPKVRAPGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSGLPELE 365
            P S L  PK+R P     S+ LAKRH SQPQ+      R+      A S + P    E +
Sbjct: 432  PSSHLPPPKLRIPNVFSISVALAKRHLSQPQLSSD---RMFGTNRNAISMIRPLRPQETD 488

Query: 366  SR---ARSREEPEKMEMEEPPPAGKNEERESPKALGAE----LEEVELGNKPPTPPLHQF 418
                   S E  E M+          +  +SP +   E     ++V   +KPPTPPLH+F
Sbjct: 489  LDLVDGDSTEVLENMDTSCDDGLFSYDSLDSPNSDDQEHCDSAKKVAY-SKPPTPPLHRF 547

Query: 419  SSWESRIYAVATSGMRLSDMSPRSNTACCASSPPALVSPGSFSGLVYKNVTVPVYTALKG 478
             SWESRIYAVA SG+R+S+     +    +++  +  + G ++ L+YKN+T PVYT LKG
Sbjct: 548  PSWESRIYAVAKSGIRMSEAFNMESVNKNSAATLSYTTSGLYTSLIYKNMTTPVYTTLKG 607

Query: 479  RATQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSE 538
            +ATQIS+ PF+D+SSGS+++ SS++S R S   S+SR  SG GSPRA+KRGVS+SS++SE
Sbjct: 608  KATQISSSPFLDDSSGSEEEDSSRSSSRTS--ESDSRSRSGPGSPRAMKRGVSLSSVASE 665

Query: 539  GDYAIPPDACSLDSDYSEPEHKLQRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRR 598
             DYAIPPDA S D++YS+PE KL +T S S+D      E LEKSGYLLKM  +VK+WKRR
Sbjct: 666  SDYAIPPDAYSTDTEYSQPEQKLPKTCSSSSDNGK--NEPLEKSGYLLKMSGKVKSWKRR 723

Query: 599  WFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPS 658
            WFVL+ G+++YYKSPSDVIRKPQG ++L++ C I+RG+  QT QL +EK TYYLTADSP+
Sbjct: 724  WFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLTTEKHTYYLTADSPN 783

Query: 659  LLEEWIRVLQSLLKVQATGPPALLRGGTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYR 718
            +LEEWI+VLQ++L+VQA  P +L   G KPT+KG LTKVKHG+SK VWC L+GK  YY+R
Sbjct: 784  ILEEWIKVLQNVLRVQAANPLSLQPEG-KPTMKGLLTKVKHGYSKRVWCTLIGKTLYYFR 842

Query: 719  SHEDKRPLGCLPVRDAHIEEVDRSCDSDEDYEAGGTRRLLSSHCTLVIHPTEHSPTYLLI 778
            S EDK PLG + + +A +EEVDRSCDSDEDYEA G R LLS+H T+VIHP +  PTYLLI
Sbjct: 843  SQEDKFPLGQIKLWEAKVEEVDRSCDSDEDYEASG-RSLLSTHYTIVIHPKDQGPTYLLI 901

Query: 779  GTKHEKDTWLYHLTVAAGGSSAKVGTAYEQLIGKLMDGEGDPDSPLWRHPMLCYSKDGLY 838
            G+KHEKDTWLYHLTVAAG ++  VG+ +EQL+ KL++ +G+P S +WRHP LC+SK+G+ 
Sbjct: 902  GSKHEKDTWLYHLTVAAGSNNVNVGSEFEQLVCKLLNIDGEPSSQIWRHPTLCHSKEGII 961

Query: 839  ASLTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIY 898
            + LTTLPSEALQTEA+KLFK+CQLFIN  V++ ++DYH+SLAQ+ALQ+CL HPELQ+EI 
Sbjct: 962  SPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHISLAQSALQICLTHPELQNEIC 1021

Query: 899  CQLMKQTSCRPPQKY-SLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPRSETGQYA 957
            CQL+KQT  R PQ     +Q WQLLALC  LFLP H FLW ++  L+R+AD R+E G+YA
Sbjct: 1022 CQLIKQTRRRQPQNQPGPLQGWQLLALCVGLFLPHHPFLWLLRLHLKRNADSRTEFGKYA 1081

Query: 958  TYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSS 1017
             YCQR VERT + G+REARPSRME++S LLRNP+HHSLPFSIPVHF NG Y VVGFD S+
Sbjct: 1082 IYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSLPFSIPVHFMNGIYQVVGFDAST 1141

Query: 1018 TVDEFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELH 1077
            TV+EFL  LNQ+ GMRKP+ SGFALFTDDPSGRDLEHCLQG++KICD ISKWEQA KE  
Sbjct: 1142 TVEEFLNTLNQDTGMRKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKEQQ 1201

Query: 1078 PGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELALEMA 1137
            PGK E GTR V+L YKNRLYF  Q +GETDRE+LLL  QT+ +I+ G FP+NK+LALEMA
Sbjct: 1202 PGKCE-GTRTVRLTYKNRLYFSVQARGETDREKLLLMYQTNDQIINGLFPLNKDLALEMA 1260

Query: 1138 ALMAQVEYGDLEKP-ALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHGAPAEQLRHLADML 1196
            AL++QVE GD E+P + P    T+  K    L+QV+++F+P+RYR G   EQLR L   L
Sbjct: 1261 ALLSQVEIGDFERPFSTPAGHVTNQCKVNQTLKQVIEKFYPKRYRDGCSEEQLRQLCQRL 1320

Query: 1197 TTKWATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQLSSKENALVWIAVNEDGVSI 1256
            +T+W  L+G S  +C+RIYLTVARKWPFFGAKLF A+P   SS  +  +W+AV+EDG+S+
Sbjct: 1321 STRWMALRGHSAADCVRIYLTVARKWPFFGAKLFLAKPITPSSLGSTFLWLAVHEDGLSL 1380

Query: 1257 LDHNTMQVHITYPYSSVTTFGGCRDDFMLVIRSIPDKSSGKSHIEKLIFRMAAPKIAEAT 1316
            L++N+M++ ++Y Y S+ TFGG +DDFM+VI +   K       EKL+F MA PKI E T
Sbjct: 1381 LEYNSMRLIVSYVYKSLMTFGGYQDDFMVVINNTHSKD---KPTEKLLFAMAKPKILEIT 1437

Query: 1317 FIMASYMNH------------CTTTVNPPTNPPGACQLWELDGRQFFSSVSCATKGPTLL 1364
             ++ASY+N+                ++  T  P A     + G Q   S S  TKGPTLL
Sbjct: 1438 LLIASYINNFHQQKAAFHHLSAPALLSAQTRGPQA----RMMGSQPLLSSSRPTKGPTLL 1493



 Score =  181 bits (459), Expect = 4e-45
 Identities = 91/171 (53%), Positives = 133/171 (77%), Gaps = 1/171 (0%)

Query: 1   MAELKVEAPASVDWQKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENA 60
           MAEL  E    VDW++RC+ LE+QL +FR+QASKIRELLA+KMQ+LE+++++AE++AE A
Sbjct: 1   MAELS-EPEGPVDWKERCVALESQLMKFRVQASKIRELLAEKMQQLERQVIDAERQAEKA 59

Query: 61  ETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEE 120
             QV VME+K+K +N++  +SE  L+ K Q+L   I+ KD++I  LE QLE+QKQ+R +E
Sbjct: 60  FQQVQVMEDKLKAANIQTSESETRLYNKCQDLESLIQEKDDVIQNLELQLEEQKQIRIQE 119

Query: 121 AKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALEAIQ 171
           AK ++EKAAKIKEWVT+KL +LE+ENQ+L+  NQ   E++ ++Q  L+ +Q
Sbjct: 120 AKIIEEKAAKIKEWVTVKLNELELENQNLRLINQNQTEEIRTMQSKLQEVQ 170


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  113 bits (282), Expect = 1e-24
 Identities = 157/708 (22%), Positives = 276/708 (38%), Gaps = 98/708 (13%)

Query: 626  LNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQ-SLLKVQATGPPALLRG 684
            ++S C     +   +F +I+  +  +  AD+P  +  WI +LQ S    +  G   ++RG
Sbjct: 1338 IDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHHWITLLQRSKGDTRVEGQEFIVRG 1397

Query: 685  GTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYRSHEDKR-PLGCLPVRD-AHIEEVDRS 742
                 VK    K+     K  W  L      YY+S E     LG L +     +   D  
Sbjct: 1398 WLHKEVKN-SPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLGTLVLNSLCSVVPPDEK 1456

Query: 743  CDSDEDYEAGGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHLTVAAGGSSAKV 802
               +  Y           HC  +     +  T      ++  DT             A +
Sbjct: 1457 IFKETGY--WNVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDT------------KAPI 1502

Query: 803  GTAYEQLIGKLMDG--EGDPDSPLW-RHPMLCYSKDGLYASLTTLPS------------- 846
             T  +QLI  + +     D    ++ R+P+L Y+   L++ L  LP              
Sbjct: 1503 DTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINLNLLKDKGY 1562

Query: 847  EALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQLMKQTS 906
              LQ EA+K+F S Q       +  S+   + + Q  LQ       L+ E+YCQL+KQT+
Sbjct: 1563 TTLQDEAIKIFNSLQ-------QLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTN 1615

Query: 907  CRP-PQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHAD--PRSETGQYATYCQRA 963
              P P     +  WQ+L   +  FLP    L Y+K  L+R  +  P SE  +YA +   +
Sbjct: 1616 KVPHPGSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIREQFPGSEMEKYALFTYES 1675

Query: 964  VERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSSTVDEFL 1023
            +++T     RE  PSR E+ +++      H    +  V+   G    +  +  +T  E +
Sbjct: 1676 LKKTKC---REFVPSRDEIEALI------HRQEMTSTVYCHGGGSCKITINSHTTAGEVV 1726

Query: 1024 QRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSEG 1083
            ++L + + M + S + FALF  + +G  ++  ++    + D ++K+E+         SE 
Sbjct: 1727 EKLIRGLAM-EDSRNMFALF--EYNGH-VDKAIESRTVVADVLAKFEKL-----AATSEV 1777

Query: 1084 GTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELALEMAALMAQV 1143
            G    K  +K   +  +    +   E   +  Q    ++ G  P  +E    +AAL  Q 
Sbjct: 1778 GDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQVLAALRLQY 1837

Query: 1144 EYGD--LEKPALPGPGGTSPAKAQHLLQQVLDRFHP-----------------RRYRHGA 1184
              GD  L     P     S  + +  + Q    F P                 R +R G+
Sbjct: 1838 LQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGS 1897

Query: 1185 PAEQL---RHLADM------------LTTKWATLQGCSPPECIRIYLTVARKWPFFGAKL 1229
               Q      + DM            +  KW   QG +  + +  Y+ + ++WP +G+ L
Sbjct: 1898 VVRQKVEEEQMLDMWIKEEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTL 1957

Query: 1230 FAAQPAQLSSKENALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFG 1277
            F  +  +    +   +W+ V+ D VS+      +    + Y  + +FG
Sbjct: 1958 FDVECKEGGFPQE--LWLGVSADAVSVYKRGEGRPLEVFQYEHILSFG 2003



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 8/96 (8%)

Query: 581  KSGYLLKMGSQVKT-----WKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRG 635
            K G+L K G    T     WK+RWFVLRQ ++MY+++ S+   K +G V++ +  +I+  
Sbjct: 1215 KQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSE--EKLKGTVEVRTAKEIIDN 1272

Query: 636  EGSQT-FQLISEKKTYYLTADSPSLLEEWIRVLQSL 670
               +    +I   +T++L A+SP    +W  VL  +
Sbjct: 1273 TTKENGIDIIMADRTFHLIAESPEDASQWFSVLSQV 1308



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 35/159 (22%), Positives = 76/159 (47%), Gaps = 5/159 (3%)

Query: 15  QKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLS 74
           +K  +  + QL R ++     R+LLA+K ++ E++  E E++ +  E +    E + + +
Sbjct: 789 KKAAIVFQKQL-RGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEE-RERERERREA 846

Query: 75  NLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEW 134
            L+    E +  ++  E L+  + + EL  +LE Q E ++       +   E   ++KE 
Sbjct: 847 ELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQ 906

Query: 135 VTLKLAKLEMEN-QHLKSHNQRLVEQVG--SLQDALEAI 170
             L L +  ++  Q  +    R +E+    + Q+ LE++
Sbjct: 907 QELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESL 945



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 8/87 (9%)

Query: 596  KRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIV-------RGEGSQTFQLISEKK 648
            K+RWFVL    + YYKS S+      G + LNS C +V       +  G     +   K 
Sbjct: 1415 KKRWFVLTHNSLDYYKS-SEKNALKLGTLVLNSLCSVVPPDEKIFKETGYWNVTVYGRKH 1473

Query: 649  TYYLTADSPSLLEEWIRVLQSLLKVQA 675
             Y L     +    W   +Q++   +A
Sbjct: 1474 CYRLYTKLLNEATRWSSAIQNVTDTKA 1500


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 102/401 (25%), Positives = 165/401 (41%), Gaps = 44/401 (10%)

Query: 888  LVHPELQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHA 947
            ++ P L+ EIYCQ+ KQ +   P K S  + W L++LC   F P   F+ Y++  +  H 
Sbjct: 1162 ILRPALRDEIYCQISKQLT-HNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRNFI--HG 1218

Query: 948  DPRSETGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGT 1007
             P      YA YC+  + RT   G R   PS +E+ +   +       P  +PV F +GT
Sbjct: 1219 GPPG----YAPYCEERLRRTFVNGTRTQPPSWLELQATKSKK------PIMLPVTFMDGT 1268

Query: 1008 YHVVGFDGSSTVDEFLQRLNQEIGMRKPSHSGFALFT---DDPSGRDLEHCLQGSVKICD 1064
               +  D ++T  E    L  +I ++     GF+L+    D  S         GS  + D
Sbjct: 1269 TKTLLTDSATTAKELCNALADKISLK--DRFGFSLYIALFDKVSSLG-----SGSDHVMD 1321

Query: 1065 AISKWEQAMKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAG 1124
            AIS+ EQ  KE    +     R   L ++  ++       E +    L+  Q  R +  G
Sbjct: 1322 AISQCEQYAKEQGAQERNAPWR---LFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFG 1378

Query: 1125 RFPINKELAL-EMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHG 1183
             +   KE  L E+A+    V+YG             S    + LL  V      R     
Sbjct: 1379 EYRCEKEDDLAELASQQYFVDYG-------------SEMILERLLNLVPTYIPDREITPL 1425

Query: 1184 APAEQLRHLADMLTTKWATLQGCSPPECIR-IYLTVAR-KWPFFGAKLFAAQPAQLSSKE 1241
               E+   LA     K    Q  +  + ++   ++ AR KWP   ++ + A      S  
Sbjct: 1426 KTLEKWAQLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLP 1485

Query: 1242 NALVWIAVNEDGVSILD-HNTMQVHITYP-YSSVTTFGGCR 1280
               V +AVN  GV  +D    + + +++P   +V++   CR
Sbjct: 1486 KNDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRECR 1526



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 87/400 (21%), Positives = 171/400 (42%), Gaps = 36/400 (9%)

Query: 893  LQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPRSE 952
            L+ E Y Q++KQ +     +YS  + W+LL LC  LF P +  L +V++ LQ       +
Sbjct: 1809 LKDEAYVQILKQLTDNHI-RYSEERGWELLWLCTGLFPPSNILLPHVQRFLQSR-----K 1862

Query: 953  TGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVG 1012
                A  C + +++ LR G R+  P  +EV +I      H +      V+F + T     
Sbjct: 1863 HCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQ-----HKTTQIFHKVYFPDDTDEAFE 1917

Query: 1013 FDGSSTVDEFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQA 1072
             + S+   +F Q +   + ++  S  GF+LF       D    +  +    D +      
Sbjct: 1918 VESSTKAKDFCQNIATRLLLK--SSEGFSLFV---KIADKVLSVPENDFFFDFVRHLTDW 1972

Query: 1073 MKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETD-RERLLLASQTSREIVAGRFPINKE 1131
            +K+  P K      +   ++  +  + + V G+    + +    Q   + + G     +E
Sbjct: 1973 IKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTRE 2032

Query: 1132 LALEMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLL-QQVLDRFHPRRYRHGAPAEQLR 1190
              L++ AL+ +V++ + +K   P    + P   + L+ Q ++ +  P  ++    A   +
Sbjct: 2033 EVLQLGALIYRVKFEE-DKSYFP----SIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNK 2087

Query: 1191 HLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQLSSKENALVWIAVN 1250
            H             G S  E    +L +  KWP FG+  F  +     +    L+ IA+N
Sbjct: 2088 H------------AGKSKEEAKLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILL-IAIN 2134

Query: 1251 EDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFMLVIRSI 1290
            + GVS++D  T  +  T+P++ ++ +      F + I ++
Sbjct: 2135 KYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNL 2174


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 98/377 (25%), Positives = 153/377 (40%), Gaps = 42/377 (11%)

Query: 888  LVHPELQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHA 947
            ++ P L+ EIYCQ+ KQ +   P K S  + W L++LC   F P   F+ Y++  +  H 
Sbjct: 1162 ILRPALRDEIYCQISKQLT-HNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRNFI--HG 1218

Query: 948  DPRSETGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGT 1007
             P      YA YC+  + RT   G R   PS +E+ +   +       P  +PV F +GT
Sbjct: 1219 GPPG----YAPYCEERLRRTFVNGTRTQPPSWLELQATKSKK------PIMLPVTFMDGT 1268

Query: 1008 YHVVGFDGSSTVDEFLQRLNQEIGMRKPSHSGFALFT---DDPSGRDLEHCLQGSVKICD 1064
               +  D ++T  E    L  +I ++     GF+L+    D  S         GS  + D
Sbjct: 1269 TKTLLTDSATTAKELCNALADKISLK--DRFGFSLYIALFDKVSSLG-----SGSDHVMD 1321

Query: 1065 AISKWEQAMKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAG 1124
            AIS+ EQ  KE    +     R   L ++  ++       E +    L+  Q  R +  G
Sbjct: 1322 AISQCEQYAKEQGAQERNAPWR---LFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFG 1378

Query: 1125 RFPINKELAL-EMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHG 1183
             +   KE  L E+A+    V+YG             S    + LL  V      R     
Sbjct: 1379 EYRCEKEDDLAELASQQYFVDYG-------------SEMILERLLNLVPTYIPDREITPL 1425

Query: 1184 APAEQLRHLADMLTTKWATLQGCSPPECIR-IYLTVAR-KWPFFGAKLFAAQPAQLSSKE 1241
               E+   LA     K    Q  +  + ++   ++ AR KWP   ++ + A      S  
Sbjct: 1426 KTLEKWAQLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLP 1485

Query: 1242 NALVWIAVNEDGVSILD 1258
               V +AVN  GV  +D
Sbjct: 1486 KNDVIVAVNWTGVYFVD 1502



 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 88/400 (22%), Positives = 173/400 (43%), Gaps = 38/400 (9%)

Query: 893  LQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPRSE 952
            L+ E Y Q++KQ +     +YS  + W+LL LC  LF P +  L +V++ LQ       +
Sbjct: 1771 LKDEAYVQILKQLTDNHI-RYSEERGWELLWLCTGLFPPSNILLPHVQRFLQSR-----K 1824

Query: 953  TGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVG 1012
                A  C + +++ LR G R+  P  +EV +I      H +      V+F + T     
Sbjct: 1825 HCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQ-----HKTTQIFHKVYFPDDTDEAFE 1879

Query: 1013 FDGSSTVDEFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQA 1072
             + S+   +F Q +   + ++  S  GF+LF       D    +  +    D +      
Sbjct: 1880 VESSTKAKDFCQNIATRLLLK--SSEGFSLFV---KIADKVLSVPENDFFFDFVRHLTDW 1934

Query: 1073 MKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETD-RERLLLASQTSREIVAGRFPINKE 1131
            +K+  P K      +   ++  +  + + V G+    + +    Q   + + G     +E
Sbjct: 1935 IKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTRE 1994

Query: 1132 LALEMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLL-QQVLDRFHPRRYRHGAPAEQLR 1190
              L++ AL+ +V++ + +K   P    + P   + L+ Q ++ +  P  ++    A   +
Sbjct: 1995 EVLQLGALIYRVKFEE-DKSYFP----SIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNK 2049

Query: 1191 HLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQLSSKENALVWIAVN 1250
            H             G S  E    +L +  KWP FG+  F  Q  + +  E  ++ IA+N
Sbjct: 2050 H------------AGKSKEEAKLAFLKLIFKWPTFGSAFF-EQTTEPNFPE--ILLIAIN 2094

Query: 1251 EDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFMLVIRSI 1290
            + GVS++D  T  +  T+P++ ++ +      F + I ++
Sbjct: 2095 KYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNL 2134


>gi|40255047 pleckstrin homology domain containing, family H (with
            MyTH4 domain) member 3 [Homo sapiens]
          Length = 793

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 117/485 (24%), Positives = 183/485 (37%), Gaps = 78/485 (16%)

Query: 798  SSAKVGTAYEQLIGKLMDGEGDPDSPLW---RHPMLCYSKDGLYASLTTLPSEA------ 848
            S A + T  + L+  + +  GDP++      R+P+L ++   LYA L  LP         
Sbjct: 200  SKAPLETPTQLLLRDIQESCGDPEAVALIYLRNPILRHTSGALYAPLLPLPYGVSAPGPG 259

Query: 849  ---LQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQLMKQT 905
               L+ EA++LF + Q                 L Q  LQ C   P L+ E++ QL KQT
Sbjct: 260  YAPLREEAVRLFLALQALEGARRPGP-------LMQGVLQTCRDLPALRDELFLQLAKQT 312

Query: 906  S--CRPP-----QKYSLMQCWQLLALCAPLFLP----QHHFLWYVKQQLQRHADPRSETG 954
            S    PP     Q  + ++ WQLL   +  F P    + H L ++++  Q  A P SE  
Sbjct: 313  SGPAGPPGLPATQDPAALRYWQLLTCMSCTFRPGGAVRGHLLGHLERTEQ--ALPDSELA 370

Query: 955  QYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFD 1014
            +YA + ++A+    RT  RE  PS  E+ ++  R            VH        V  D
Sbjct: 371  EYARFIRKALG---RTRGRELVPSLAEISALSQRQ------ELLCTVHCPGAGACAVAID 421

Query: 1015 GSSTVDEFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMK 1074
              +T  E  + L   +G+ + S + FAL+    +    E  L G   + D ++++E    
Sbjct: 422  SHTTAGEVARELVGRLGLAR-SRNAFALYEQRGA---QERALAGGTLVADVLTRFENLAA 477

Query: 1075 ELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELAL 1134
            E   G  +      +L  +       +       E   L  Q    ++ GR P   +   
Sbjct: 478  E-EAGLEDSPDSGWRLCLRLHGPLHPEGLSPDGHELPFLFEQAHALLLRGRPPPPDDTLR 536

Query: 1135 EMAALMAQVEYGD-------------LEKPA---------LPGPGGTSPAKAQHLLQQVL 1172
             +AAL  Q  + D             L  PA          P P  ++   A  L    L
Sbjct: 537  ALAALRLQSLHRDFSPRVPLPRLDRLLPPPAPPREDPPRPTPRPPPSAALLAGALWSPGL 596

Query: 1173 DRFHPRRYRHGAPAEQLRHL----------ADMLTTKWATLQGCSPPECIRIYLTVARKW 1222
             +    R R G        +          A  +   W  L+G    E +  YL +A + 
Sbjct: 597  AKRRAERARRGGAGRTAGSIAREGGGGAGTAAAVLGGWKRLRGMGRAEAMAAYLALAAQC 656

Query: 1223 PFFGA 1227
            P FGA
Sbjct: 657  PGFGA 661


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 91/392 (23%), Positives = 153/392 (39%), Gaps = 50/392 (12%)

Query: 888  LVHPELQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHA 947
            ++ P L+ EIYCQ+ KQ S    +  SL + W LL+LC   F P   F+ Y+   + +  
Sbjct: 1101 ILRPSLRDEIYCQICKQLS-ENFKTSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQ-- 1157

Query: 948  DPRSETGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGT 1007
                    Y  +C   + RT   G R   P+ +E+ ++  +          I V    G 
Sbjct: 1158 ----GPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKK------HIPIQVILATGE 1207

Query: 1008 YHVVGFDGSSTVDEFLQRLNQEIGMRKPSHSGFAL-------FTDDPSGRDLEHCLQGSV 1060
               V  D +ST  E    +  + G+    H GF+L       F    SGRD         
Sbjct: 1208 SLTVPVDSASTSREMCMHIAHKQGL--SDHLGFSLQVAVYDKFWSLGSGRD--------- 1256

Query: 1061 KICDAISKWEQAMKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSRE 1120
             + DAI++ EQ  +E    + +   R+    ++   +       E      L+  Q  R 
Sbjct: 1257 HMMDAIARCEQMAQERGESQRQSPWRI---YFRKEFFTPWHDSREDPVSTELIYRQVLRG 1313

Query: 1121 IVAGRFPINKELALEMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRY 1180
            + +G +   KE   E+  L+A+  Y  L        G ++ +KA   +Q++L    P + 
Sbjct: 1314 VWSGEYSFEKE--EELVELLARHCYVQL--------GASAESKA---VQELLPSCIPHKL 1360

Query: 1181 RHGAPAEQLRHLADMLTTKWATLQGCSPPECIRIYLTVARK--WPFFGAKLFAAQPAQLS 1238
                P ++   L      K    Q    P  +R  +  A +  WP   ++LF        
Sbjct: 1361 YRTKPPDRWASLVTAACAKAPYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGP 1420

Query: 1239 SKENALVWIAVNEDGVSILD-HNTMQVHITYP 1269
                  + +AVN  G+  LD    M + +++P
Sbjct: 1421 RLPKTQLILAVNWKGLCFLDQQEKMLLELSFP 1452



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 83/417 (19%), Positives = 167/417 (40%), Gaps = 38/417 (9%)

Query: 877  VSLAQTALQVCLVHPELQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFL 936
            + L      + L HP LQ E+YCQ++KQ +     ++S  + WQLL LC  LF P    L
Sbjct: 1690 LELTDQIFTLALQHPALQDEVYCQILKQLT-HNSNRHSEERGWQLLWLCTGLFPPSKGLL 1748

Query: 937  WYVKQQLQRHADPRSETGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLP 996
                   Q+  D R      A  C R +++ LRTG R+  P ++EV +        +   
Sbjct: 1749 ----PHAQKFIDTR-RGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEA-----AEQNVSR 1798

Query: 997  FSIPVHFTNGTYHVVGFDGSSTVDEFLQRLNQEIGMRKPSHSGFALF---TDDPSGRDLE 1053
                ++F N T  ++    ++ V +    +   + +   S  G +LF   +D    +   
Sbjct: 1799 ICHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQL--ASWEGCSLFIKISDKVISQKEG 1856

Query: 1054 HCLQGSVKICDAISKWEQAMKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLL 1113
                 S++    +S W +  K    G     T   ++ +  +L+       + + + +L 
Sbjct: 1857 DFFFDSLR---EVSDWVKKNKPQKEGAPV--TLPYQVYFMRKLWLNISPGKDVNADTILH 1911

Query: 1114 ASQTSREIVAGRFPINKELALEMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLD 1173
              Q   + + G    ++E A+ +A L+ + ++ +        P             ++L 
Sbjct: 1912 YHQELPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVP-------------KILR 1958

Query: 1174 RFHPRRYRHGAPAEQLRHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQ 1233
               P        +E+ +     +   +   +  +  E    +L    +WP FG+  F  +
Sbjct: 1959 ELVPENLTRLMSSEEWK---KSILLAYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVK 2015

Query: 1234 PAQLSSKENALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFMLVIRSI 1290
                 S  + ++ IA+N  GV ++   T  +  TYP++ ++++      F + + S+
Sbjct: 2016 QTSEPSYPDVIL-IAINRHGVLLIHPKTKDLLTTYPFTKISSWSSGSTYFHMALGSL 2071


>gi|154146216 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 2 [Homo
           sapiens]
          Length = 425

 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 12/128 (9%)

Query: 561 LQRTSSY-STDGLGLG-GESLEKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIR 618
           L+R+ SY  T G     G  L KSGY +K G+  K+WKRR+F L    I Y+K   D  R
Sbjct: 179 LRRSQSYIPTSGCRASTGPPLIKSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQD--R 236

Query: 619 KPQGQVDLNS-----RCQIVRGE---GSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL 670
           +P   + L        C +  G+       F++I+  +T+Y+ ADSP  +  WI+ + + 
Sbjct: 237 EPLRTIFLKDVLKTHECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAA 296

Query: 671 LKVQATGP 678
           ++     P
Sbjct: 297 VQALKCHP 304


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 94/460 (20%), Positives = 191/460 (41%), Gaps = 60/460 (13%)

Query: 829  MLCYSKDGLYASLTTLPSEALQTEALKLFKSCQLFI-NVPVEAASVDYHVSLAQTALQVC 887
            MLC++K  L  SL  L   +L   A  +F +   F+ + P++  S    + +    L++C
Sbjct: 3047 MLCFTKTPLQESLIELSDSSLSKMATDMFLAVMRFMGDAPLKGQS---DLDVLCNLLKLC 3103

Query: 888  LVHPELQSEIYCQLMKQTSCRPPQKY-SLMQCWQLLAL------CAPLFLPQHHFLWYVK 940
              H  ++ E YCQ++KQ +     K  S  + W+LL +      C+ +    H  L    
Sbjct: 3104 GDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVL---HPHLTRFL 3160

Query: 941  QQLQRHADPRSETGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIP 1000
            Q + R   P       A  C++ +++TLR G R   PS +E+ ++L        L F +P
Sbjct: 3161 QDVSR--TPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQL-FLLP 3217

Query: 1001 VHFTNGTYHVVGFDGSSTVDEFLQRLNQEIGMRKP-SHSGFALFTDDPSGRDLEHC-LQG 1058
                 G    +     +   + ++ +  E+ + +P + + + +F     G+ +  C L  
Sbjct: 3218 ----GGLERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFVVTNRGQHV--CPLSR 3271

Query: 1059 SVKICDAISKWEQAMKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTS 1118
               I D  S+ EQ          +GG     +++  R+ +   +K E +    +  +Q  
Sbjct: 3272 RAYILDVASEMEQV---------DGG----YMLWFRRVLWDQPLKFENELYVTMHYNQVL 3318

Query: 1119 REIVAGRF---PINK--ELALEMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLD 1173
             + + G F   P ++  E  L+  + +A +++   +   LP             +++V +
Sbjct: 3319 PDYLKGLFSSVPASRPSEQLLQQVSKLASLQHRAKDHFYLPS------------VREVQE 3366

Query: 1174 RFHPRRYRHGAPAEQLRHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQ 1233
                + YR  A +  L    ++++      Q  SP +    +L +    P FG+  F  Q
Sbjct: 3367 YIPAQLYRTTAGSTWL----NLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFFIQ 3422

Query: 1234 PAQLSSKENALVWIAVNEDGVSILDHNTMQVHITYPYSSV 1273
                 +     + +A+N +G++ L   T ++ + +P   +
Sbjct: 3423 SCSNIAVPAPCI-LAINHNGLNFLSTETHELMVKFPLKEI 3461


>gi|158631203 dual adaptor of phosphotyrosine and
           3-phosphoinositides [Homo sapiens]
          Length = 280

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 34/92 (36%), Positives = 52/92 (56%), Gaps = 7/92 (7%)

Query: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQ- 639
           K GYL K G  VKTWK RWF L + ++ Y+K    +  +P   +DL + C  V+ + SQ 
Sbjct: 167 KEGYLTKQGGLVKTWKTRWFTLHRNELKYFK--DQMSPEPIRILDL-TECSAVQFDYSQE 223

Query: 640 ---TFQLISEKKTYYLTADSPSLLEEWIRVLQ 668
               F L+   +T+YL A +    +EWI++L+
Sbjct: 224 RVNCFCLVFPFRTFYLCAKTGVEADEWIKILR 255


>gi|50234893 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 1 [Homo
           sapiens]
          Length = 404

 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 29/100 (29%), Positives = 55/100 (55%), Gaps = 8/100 (8%)

Query: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGS-- 638
           K+GY +K G+ +K WKRR+F L +  I Y+K  S++ ++P   + L    ++   + S  
Sbjct: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFK--SELEKEPLRVIPLKEVHKVQECKQSDI 251

Query: 639 ----QTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKVQ 674
                 F++++  +T+Y+ ADSP  +  WI+ +   +  Q
Sbjct: 252 MMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291


>gi|31377720 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 1 [Homo
           sapiens]
          Length = 404

 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 29/100 (29%), Positives = 55/100 (55%), Gaps = 8/100 (8%)

Query: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGS-- 638
           K+GY +K G+ +K WKRR+F L +  I Y+K  S++ ++P   + L    ++   + S  
Sbjct: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFK--SELEKEPLRVIPLKEVHKVQECKQSDI 251

Query: 639 ----QTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKVQ 674
                 F++++  +T+Y+ ADSP  +  WI+ +   +  Q
Sbjct: 252 MMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 6/107 (5%)

Query: 571 GLGLGGESLEKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRC 630
           G G GG    + G+L K  + +K ++RRWFVL  G + YY+S +++    +G ++L +  
Sbjct: 81  GSGAGGSGSAREGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATAN 140

Query: 631 QIVRGEGSQTFQLISE--KKTYYLTADSPSLLEEWIRVLQSLLKVQA 675
             V  E S  F +IS    +TY+L A S    + W+  L+ L K +A
Sbjct: 141 ITV--EDSCNF-IISNGGAQTYHLKASSEVERQRWVTALE-LAKAKA 183


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 24/136 (17%)

Query: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQT 640
           K+G+L K  S +K W++RWFVLR  Q+ YYK   ++  KPQG + L         +G+Q 
Sbjct: 40  KAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEI--KPQGFISL---------QGTQV 88

Query: 641 FQLI--SEKKTYYLTADSPSLLEEWIRVLQSLLKVQATGPPALLRGGTKPTVKGWLTKVK 698
            +L    E    +L   SP    E         KV A     LL   ++  ++ W+  ++
Sbjct: 89  TELPPGPEDPGKHLFEISPGGAGE-------REKVPANPEALLLMASSQRDMEDWVQAIR 141

Query: 699 HGHSKVVWCALVGKIF 714
               +V+W  L G IF
Sbjct: 142 ----RVIWAPLGGGIF 153


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 6/103 (5%)

Query: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRC---QIVRGEG 637
           K GY++K G + K W  RWFVL+   I YY   S+ ++  +G + L+  C    +   +G
Sbjct: 213 KQGYMMKKGHRRKNWTERWFVLKPNIISYY--VSEDLKDKKGDILLDENCCVESLPDKDG 270

Query: 638 SQTFQLIS-EKKTYYLTADSPSLLEEWIRVLQSLLKVQATGPP 679
            +   L+    KT+ ++A      +EWI+ + S + +   G P
Sbjct: 271 KKCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSP 313



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 21/179 (11%)

Query: 3   ELKVEAPASVDWQKRCLTLETQLFRFRLQASKIRELLADKMQELE---QRLLEAE----- 54
           E K      V+ Q R     T+L R +L   ++ E +A K  ELE   QR+ E E     
Sbjct: 372 EEKKRLQTQVELQAR---FSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLK 428

Query: 55  -QRAENAETQVGVMEEKVKLSNLKNVDSEGS----LHRKYQELLKAIKGKDELISQLEAQ 109
            Q A   E Q    EE V+    + ++ E S    L + + E  +AI+  +    +LE Q
Sbjct: 429 LQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQ 488

Query: 110 LEKQKQMRAEEAKTVQ----EKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQ 164
              ++Q   E  + ++    E+   ++++  +K  KLEM     KS   ++    G ++
Sbjct: 489 RVLKEQALQEAMEQLEQLELERKQALEQYEEVK-KKLEMATNKTKSWKDKVAHHEGLIR 546


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 15/121 (12%)

Query: 553 DYSEPEHKLQRTSSYSTDGLGLGGESLEKSGYLLKMGSQV-KTWKRRWFVLRQGQIMYYK 611
           D+S  + KL+    Y+ D        +   GYL K  S   KTW RRWF ++  Q++Y K
Sbjct: 249 DFSSDDSKLE----YNVDA----ANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK 300

Query: 612 SPSDVIRKPQGQVDLNSRCQIVRGEGSQ---TFQLISEKKTYYLTADSPSLLEEWIRVLQ 668
              D    P   V+    C +   E  +    F+++S  K+  L ADS  L + WI+ +Q
Sbjct: 301 KFKD---NPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQ 357

Query: 669 S 669
           +
Sbjct: 358 T 358


>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
           sapiens]
          Length = 694

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 21/113 (18%)

Query: 574 LGGESLEKSGYLLKMGSQVK----TWKRRWFVLRQGQIM-------YYKSPSDVIRKPQG 622
           + G  +  SG+L K   + K     WKRRWFVLR G++        YYK  +D  +KP  
Sbjct: 1   MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYK--NDHAKKPIR 58

Query: 623 QVDLNSRCQIVRG--------EGSQTFQLISEKKTYYLTADSPSLLEEWIRVL 667
            +DLN   Q+  G        E S  F + +  + +YL ADS   + +W+R +
Sbjct: 59  IIDLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCI 111


>gi|46370071 GRB2-associated binding protein 1 isoform a [Homo
           sapiens]
          Length = 724

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 21/113 (18%)

Query: 574 LGGESLEKSGYLLKMGSQVK----TWKRRWFVLRQGQIM-------YYKSPSDVIRKPQG 622
           + G  +  SG+L K   + K     WKRRWFVLR G++        YYK  +D  +KP  
Sbjct: 1   MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYK--NDHAKKPIR 58

Query: 623 QVDLNSRCQIVRG--------EGSQTFQLISEKKTYYLTADSPSLLEEWIRVL 667
            +DLN   Q+  G        E S  F + +  + +YL ADS   + +W+R +
Sbjct: 59  IIDLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCI 111


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 12/108 (11%)

Query: 574 LGGESLEKS-----------GYLLKMGSQV-KTWKRRWFVLRQGQIMYYKSPSDVIRKPQ 621
           LGGE  E S           G+L K  S   KTW RRWF ++  Q++Y K   D +    
Sbjct: 250 LGGEEPEPSLREGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKKYKDPVTVVV 309

Query: 622 GQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQS 669
             + L +       E    F+++S  K+  L ADS  LL+ W+  +QS
Sbjct: 310 DDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQS 357


>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
          Length = 2186

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 42/146 (28%), Positives = 72/146 (49%), Gaps = 16/146 (10%)

Query: 549 SLDSDYSEPEHKLQRTS-SYSTDGLGLGGESLEKSGYLLKMGSQ--------VKTWKRRW 599
           S + D+ + +     TS S S  G G GG  + KSG+L K            V+++K+R+
Sbjct: 151 SFEIDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRY 210

Query: 600 FVLRQ----GQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQ--TFQLISEKKTYY-L 652
           F L Q      IM +     + ++P+G + L+S   +V+    +   F+L     TY+ L
Sbjct: 211 FQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVL 270

Query: 653 TADSPSLLEEWIRVLQSLLKVQATGP 678
            A++ S ++EWI  L  +L++   GP
Sbjct: 271 AAETESDMDEWIHTLNRILQISPEGP 296


>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
           [Homo sapiens]
          Length = 752

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 42/182 (23%), Positives = 71/182 (39%), Gaps = 4/182 (2%)

Query: 502 QASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSEGDYAIPPDACSLDSDYSEPEHKL 561
           + S  + +P +  R      SP    RG+  SS ++EG  A       L    S  +++ 
Sbjct: 79  RTSSLLLLPPTPERALFASPSPDPSPRGLGASSGAAEGAGA----GLLLGCRASMSDNQS 134

Query: 562 QRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQ 621
             +S    D     G  +E+ G L K  + +  W+ RW VL+   + YYKS  +     +
Sbjct: 135 WNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCR 194

Query: 622 GQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKVQATGPPAL 681
           G + L+             F +      +YL A  P   ++WI  ++        G  + 
Sbjct: 195 GSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESS 254

Query: 682 LR 683
           LR
Sbjct: 255 LR 256


>gi|110349763 cytohesin 1 isoform 2 [Homo sapiens]
          Length = 397

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 29/116 (25%), Positives = 60/116 (51%), Gaps = 26/116 (22%)

Query: 580 EKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDL------------- 626
           ++ G+LLK+G +VKTWKRRWF+L    + Y++  +D  ++P+G + L             
Sbjct: 262 DREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTD--KEPRGIIPLENLSIREVEDSKK 319

Query: 627 ---------NSRCQIVRGEGSQTFQLISE--KKTYYLTADSPSLLEEWIRVLQSLL 671
                    +++ Q+++   ++    + E     Y ++A +P   EEWI+ +++ +
Sbjct: 320 PNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAI 375



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 9/96 (9%)

Query: 655 DSPSLLEEWIRVLQSLLKVQATGPPA-----LLRGGTKPTVKGWLTKVKHGHSKVV---W 706
           D   L EE +R L   +K +    P      L      P  +GWL K+  G  K     W
Sbjct: 223 DGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLG-GRVKTWKRRW 281

Query: 707 CALVGKIFYYYRSHEDKRPLGCLPVRDAHIEEVDRS 742
             L     YY+    DK P G +P+ +  I EV+ S
Sbjct: 282 FILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDS 317


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 34/147 (23%), Positives = 78/147 (53%), Gaps = 8/147 (5%)

Query: 13  DWQKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVK 72
           +W+++   ++ Q  + R Q  KIRE   +KM+  E+ + E E++    E  +   EEK++
Sbjct: 311 EWEEK---IQEQEEKIREQEEKIREQ-EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 73  LSNLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIK 132
                  + E  + R+ + + +    K+E I +LE ++ +Q+++R +E K  +E+  + +
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWE----KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422

Query: 133 EWVTLKLAKLEMENQHLKSHNQRLVEQ 159
           E    + AK+  + + ++   +++ EQ
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQ 449



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 27/145 (18%), Positives = 74/145 (51%), Gaps = 9/145 (6%)

Query: 27  RFRLQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSLH 86
           + R Q  K R+   +KM + E+++ E E++ +  E ++   EEK++       + E  + 
Sbjct: 592 KIREQEEK-RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650

Query: 87  RKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAKLEMEN 146
            + +++ +    ++E + + E  + +Q++   E+ K ++E+  KI+E   +    ++ + 
Sbjct: 651 EQEEKMCE----QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM----MQEQE 702

Query: 147 QHLKSHNQRLVEQVGSLQDALEAIQ 171
           + +    +++ EQ   +Q+  E ++
Sbjct: 703 EKMWEQEEKMCEQEEKMQEQEEKMR 727



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 24/122 (19%), Positives = 64/122 (52%), Gaps = 9/122 (7%)

Query: 41  DKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSLHRKYQ---ELLKAIK 97
           +K+QE E+++ E E++    E ++   EEK++       + E  + R+ +   E  + ++
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 98  GKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLV 157
            ++E++ + E ++ +Q++M  E+ + ++E   K+ E   ++      E +  +   +++ 
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR------EQEEKRQEEEKIR 420

Query: 158 EQ 159
           EQ
Sbjct: 421 EQ 422



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 30/139 (21%), Positives = 67/139 (48%), Gaps = 6/139 (4%)

Query: 36  RELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSL---HRKYQEL 92
           R+   DKM   E+++ E E++    E ++   EEK +    K    E  +     K QE 
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ 624

Query: 93  LKAIKGKDELISQLEAQLEKQKQMRAEEAKTV---QEKAAKIKEWVTLKLAKLEMENQHL 149
            + I+ ++E I + E   ++Q++   E+ + +   +EK  + +E +  +  K+  + + +
Sbjct: 625 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKI 684

Query: 150 KSHNQRLVEQVGSLQDALE 168
           +   +++ EQ   +Q+  E
Sbjct: 685 REQEEKIREQEEMMQEQEE 703



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 24/105 (22%), Positives = 56/105 (53%), Gaps = 5/105 (4%)

Query: 33  SKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSLHRKYQEL 92
           +++ +   +KM   E+++ E E++ +  E ++   EEK++    K    E  +  K +++
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351

Query: 93  LK----AIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKE 133
            +      + ++++  Q E   EK+++MR +E + + EK  KI+E
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKIRE 395



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 29/138 (21%), Positives = 65/138 (47%), Gaps = 2/138 (1%)

Query: 34  KIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELL 93
           KIREL  +KM E E+   + E+R E  + +     ++ +    +  +       K +E  
Sbjct: 392 KIREL-EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450

Query: 94  KAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHN 153
           K +  ++E I + E   E++K+   EE    +EK  + +E +  +  K+  + + ++   
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQE 509

Query: 154 QRLVEQVGSLQDALEAIQ 171
           +++  Q   +++  E I+
Sbjct: 510 EKVWRQEEKIREQEEKIR 527



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 17/93 (18%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 41  DKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELLKAIKGKD 100
           +KMQE E+ +   E++    E ++   EEK++       + E  +  + +++ +    ++
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE----QE 716

Query: 101 ELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKE 133
           E + + E ++ +Q++   E+   ++++  K++E
Sbjct: 717 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 19/120 (15%)

Query: 29  RLQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKV-----KLSNLKNVDSEG 83
           R +  KIRE   +K QE E ++   E++    E ++   E+K+     K+   + +  E 
Sbjct: 413 RQEEEKIRE--QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470

Query: 84  SLHRKYQELL----KAIKGKDELISQLEAQLEKQKQMRAEEAKT------VQEKAAKIKE 133
              R+ QE +    + I  ++E+  Q E   E+++++R +E K       ++E+  KI+E
Sbjct: 471 K--RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 18/87 (20%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 41  DKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELLKAIKGKD 100
           +KM E E+++ E E+     E ++   E+K++    K  + E  +  + +++ +    ++
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ---EE 710

Query: 101 ELISQLEAQLEKQKQMRAEEAKTVQEK 127
           ++  Q E   E++++MR +E K  +++
Sbjct: 711 KMCEQEEKMQEQEEKMRRQEEKMWEQE 737



 Score = 32.0 bits (71), Expect = 4.2
 Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 19/131 (14%)

Query: 19  LTLETQLFRFRLQASKIR-ELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLK 77
           LT E       L  + I  E L +K  +L+++L   E  +E +E Q+ V E K KL   K
Sbjct: 198 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE--SEKSEIQLNVKELKRKLERAK 255

Query: 78  NVDSEGSLHRKYQELLKAIKG----------KDELISQLEAQLEKQKQMRAEEA-----K 122
            +  +  L  +   L K ++           ++EL ++L  Q E +K  R EE      +
Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE-EKMWRQEEKIQEWEE 314

Query: 123 TVQEKAAKIKE 133
            +QE+  KI+E
Sbjct: 315 KIQEQEEKIRE 325


>gi|195972859 cytohesin 2 isoform 2 [Homo sapiens]
          Length = 399

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 26/118 (22%)

Query: 580 EKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDL------------- 626
           ++ G+LLK+G +VKTWKRRWF+L    + Y++  +D  ++P+G + L             
Sbjct: 261 DREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTD--KEPRGIIPLENLSIREVDDPRK 318

Query: 627 ---------NSRCQIVRGEGSQTFQLISE--KKTYYLTADSPSLLEEWIRVLQSLLKV 673
                    N++ Q+++   ++    + E     Y ++A +    +EWI+ +Q+ + V
Sbjct: 319 PNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 376



 Score = 38.5 bits (88), Expect = 0.044
 Identities = 36/133 (27%), Positives = 52/133 (39%), Gaps = 14/133 (10%)

Query: 688 PTVKGWLTKVKHGHSKVV---WCALVGKIFYYYRSHEDKRPLGCLPVRDAHIEEVD--RS 742
           P  +GWL K+  G  K     W  L     YY+    DK P G +P+ +  I EVD  R 
Sbjct: 260 PDREGWLLKLG-GRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRK 318

Query: 743 CDSDEDYEAGGTRRLLSSHCTLV---IHPTEHSPTYLLIGTKHEKDTWLYHLTVAAGGSS 799
            +  E Y      +L+ +  T     +    H    +   T+ EKD W+  +  A     
Sbjct: 319 PNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAA----- 373

Query: 800 AKVGTAYEQLIGK 812
             V   YE L  +
Sbjct: 374 VSVDPFYEMLAAR 386


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 45/184 (24%), Positives = 88/184 (47%), Gaps = 19/184 (10%)

Query: 17   RCLTLETQLFRFRLQASKIRELLADKMQ-------ELEQRLLEAEQRAENAETQVGVMEE 69
            R + LE  + +  ++   + E+L +  Q       EL Q+L   ++  E  + +V   EE
Sbjct: 1526 RIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEE 1585

Query: 70   KVKLSNLKNVDSEGSLHRKYQELLK---AIKGKDELISQLEAQLEKQKQMR-AEEAKTVQ 125
            K+     +    +  L  K +EL     ++K K+E +  LE +LE +   + AE  +  +
Sbjct: 1586 KILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE 1645

Query: 126  EKAAKIKEWVTLKLAKLEME-----NQHLKSHNQRLVE---QVGSLQDALEAIQIAPSRK 177
            +K A IK+ +  ++ + E +       HL   N +L E   +V  L++ L++++ + S  
Sbjct: 1646 QKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSET 1705

Query: 178  LLVP 181
            L+VP
Sbjct: 1706 LIVP 1709



 Score = 39.3 bits (90), Expect = 0.026
 Identities = 38/172 (22%), Positives = 75/172 (43%), Gaps = 10/172 (5%)

Query: 15  QKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLS 74
           Q++ L LET+      Q +++     D   EL+   ++ +   +  E Q   ME+KVK S
Sbjct: 825 QQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK-S 883

Query: 75  NLKNVDSEGSLHRKYQELLKAI-KGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKE 133
             +  +S+     K QE  K I   K+ +I Q+    +K+ ++  ++    ++    + E
Sbjct: 884 LTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE 943

Query: 134 WVTLKLAKLEMENQHLKSH--------NQRLVEQVGSLQDALEAIQIAPSRK 177
               K    E + + +K           ++L++Q   L+  LE   +  S+K
Sbjct: 944 EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQK 995



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 39/193 (20%), Positives = 90/193 (46%), Gaps = 24/193 (12%)

Query: 14  WQKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQ---RAENAETQVGVMEE- 69
           W ++   L+ Q   ++ +  K+RE    K ++ ++ LL+ ++   +A   E     +E+ 
Sbjct: 627 WTEKLQVLKQQ---YQTEMEKLRE----KCEQEKETLLKDKEIIFQAHIEEMNEKTLEKL 679

Query: 70  KVKLSNLKNVDSEGS----LHRKYQELLKAIKGK-DELISQLEAQLEKQKQMRAEEAK-- 122
            VK + L+++ SE S       K +E L  +K + D++  +LEA++++QK    ++    
Sbjct: 680 DVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI 739

Query: 123 ------TVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALEAIQIAPSR 176
                 ++Q     +K+ +      L+  ++HLK H   +      ++ +   +Q A ++
Sbjct: 740 IKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAK 799

Query: 177 KLLVPPYGAAEQD 189
             +   Y +A  +
Sbjct: 800 LDVFQSYQSATHE 812



 Score = 32.0 bits (71), Expect = 4.2
 Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 24/161 (14%)

Query: 20   TLETQLFRFRLQ-ASKIREL------LADKMQELEQRLLEAEQRAENAETQVGVMEEKVK 72
            TL+  +  F  Q A K +EL        +K QE+E  LLE+ Q     ET   + +   K
Sbjct: 1993 TLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE----ETNQLLKKIAEK 2048

Query: 73   LSNLKNVDSEGSLHRKYQELLKAIKGK-----DELISQLEAQLEKQKQMRAEEAKTVQEK 127
              +LK         ++Y+E+L A + +      +L +QLE +L+K+ Q + E+ +     
Sbjct: 2049 DDDLKRT------AKRYEEILDAREEEMTAKVRDLQTQLE-ELQKKYQQKLEQEENPGND 2101

Query: 128  AAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALE 168
               I E  T +LA+        K   Q   EQ+ +L+D L+
Sbjct: 2102 NVTIMELQT-QLAQKTTLISDSKLKEQEFREQIHNLEDRLK 2141


>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
           3 [Homo sapiens]
          Length = 834

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 1/88 (1%)

Query: 583 GYLLKMGSQV-KTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTF 641
           GYL K  S   KTW RRWF ++  Q++Y K   D +      + L S       E    F
Sbjct: 273 GYLFKRASNAFKTWNRRWFSIQNSQLVYQKKLKDALTVVVDDLRLCSVKPCEDIERRFCF 332

Query: 642 QLISEKKTYYLTADSPSLLEEWIRVLQS 669
           +++S  K+  L ADS  L + W++ +Q+
Sbjct: 333 EVLSPTKSCMLQADSEKLRQAWVQAVQA 360


>gi|4758968 cytohesin 3 [Homo sapiens]
          Length = 399

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 26/114 (22%)

Query: 580 EKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNS----------- 628
           ++ G+LLK+G +VKTWKRRWF+L    + Y++  +D  ++P+G + L +           
Sbjct: 266 DREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTD--KEPRGIIPLENLSIREVEDPRK 323

Query: 629 -----------RCQIVRGEGSQTFQLISEKK--TYYLTADSPSLLEEWIRVLQS 669
                      + Q+++   ++    + E     Y ++A SP   EEW++ +++
Sbjct: 324 PNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKA 377



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 688 PTVKGWLTKVKHGHSKVV---WCALVGKIFYYYRSHEDKRPLGCLPVRDAHIEEVD 740
           P  +GWL K+  G  K     W  L     YY+    DK P G +P+ +  I EV+
Sbjct: 265 PDREGWLLKLG-GRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVE 319


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
           sapiens]
          Length = 645

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 17/102 (16%)

Query: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQI------VR 634
           K G+L K  S VK W++R+FVLR  Q+ YYK   D   KPQG + L   C I        
Sbjct: 49  KMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDT--KPQGCMYLPG-CTIKEIATNPE 105

Query: 635 GEGSQTFQLISE--------KKTYYLTADSPSLLEEWIRVLQ 668
             G   F++I          + +Y L A S + +EEW++ L+
Sbjct: 106 EAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLR 147



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 6/57 (10%)

Query: 687 KPTVKGWLTK----VKHGHSKVVWCALVGKIFYYYRSHEDKRPLGCLPVRDAHIEEV 739
           +P   GWL K    VK+   +  +  L  +  YYY+  ED +P GC+ +    I+E+
Sbjct: 46  RPIKMGWLKKQRSIVKNWQQR--YFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEI 100


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
           sapiens]
          Length = 638

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 17/102 (16%)

Query: 581 KSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQI------VR 634
           K G+L K  S VK W++R+FVLR  Q+ YYK   D   KPQG + L   C I        
Sbjct: 42  KMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDT--KPQGCMYLPG-CTIKEIATNPE 98

Query: 635 GEGSQTFQLISE--------KKTYYLTADSPSLLEEWIRVLQ 668
             G   F++I          + +Y L A S + +EEW++ L+
Sbjct: 99  EAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLR 140



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 6/57 (10%)

Query: 687 KPTVKGWLTK----VKHGHSKVVWCALVGKIFYYYRSHEDKRPLGCLPVRDAHIEEV 739
           +P   GWL K    VK+   +  +  L  +  YYY+  ED +P GC+ +    I+E+
Sbjct: 39  RPIKMGWLKKQRSIVKNWQQR--YFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEI 93


>gi|58331179 KIAA1688 protein [Homo sapiens]
          Length = 1114

 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 37/125 (29%), Positives = 65/125 (52%), Gaps = 4/125 (3%)

Query: 829 MLCYSKDGLYASLTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCL 888
           ML +S + +   +       ++ EA +LFK  Q+++     A +   HV+L + A +   
Sbjct: 719 MLAWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMG-DRRAKADPLHVAL-EVATKGWS 776

Query: 889 VHPELQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHAD 948
           V   L+ E+Y QL +QT+    +  SL + W+L+A+C   F P   F  Y++  + RH D
Sbjct: 777 VQG-LRDELYIQLCRQTT-ENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMD 834

Query: 949 PRSET 953
           P ++T
Sbjct: 835 PVNDT 839


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,064,745
Number of Sequences: 37866
Number of extensions: 2880509
Number of successful extensions: 15039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 724
Number of HSP's that attempted gapping in prelim test: 12087
Number of HSP's gapped (non-prelim): 3043
length of query: 1364
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1249
effective length of database: 13,892,928
effective search space: 17352267072
effective search space used: 17352267072
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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