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Search of human proteins with 54607035
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
(1822 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 3756 0.0
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 3489 0.0
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 3465 0.0
gi|47078292 integrin beta chain, beta 3 precursor [Homo sapiens] 450 e-126
gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens] 447 e-125
gi|19743815 integrin beta 1 isoform 1B precursor [Homo sapiens] 447 e-125
gi|19743813 integrin beta 1 isoform 1A precursor [Homo sapiens] 447 e-125
gi|19743823 integrin beta 1 isoform 1A precursor [Homo sapiens] 447 e-125
gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens] 447 e-125
gi|19743819 integrin beta 1 isoform 1D precursor [Homo sapiens] 447 e-125
gi|20127446 integrin, beta 5 [Homo sapiens] 436 e-121
gi|9625002 integrin, beta 6 [Homo sapiens] 433 e-121
gi|188595677 integrin, beta 2 precursor [Homo sapiens] 394 e-109
gi|89191865 integrin, beta 2 precursor [Homo sapiens] 394 e-109
gi|4504777 integrin, beta 7 [Homo sapiens] 387 e-107
gi|4504779 integrin, beta 8 precursor [Homo sapiens] 323 1e-87
gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 140 1e-32
gi|119220552 sidekick 1 [Homo sapiens] 106 2e-22
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 102 3e-21
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 102 4e-21
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 102 4e-21
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 99 4e-20
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 98 6e-20
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 97 1e-19
gi|222352127 sidekick 2 [Homo sapiens] 95 7e-19
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 91 8e-18
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 91 8e-18
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 91 8e-18
gi|153946395 tenascin C precursor [Homo sapiens] 91 1e-17
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 90 2e-17
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 3756 bits (9740), Expect = 0.0
Identities = 1822/1822 (100%), Positives = 1822/1822 (100%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG 1380
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG 1380
Query: 1381 EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGE 1440
EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGE
Sbjct: 1381 EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGE 1440
Query: 1441 HLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEH 1500
HLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEH
Sbjct: 1441 HLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEH 1500
Query: 1501 SHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGY 1560
SHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGY
Sbjct: 1501 SHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGY 1560
Query: 1561 SVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIES 1620
SVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIES
Sbjct: 1561 SVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIES 1620
Query: 1621 QVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEM 1680
QVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEM
Sbjct: 1621 QVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEM 1680
Query: 1681 AQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGG 1740
AQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGG
Sbjct: 1681 AQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGG 1740
Query: 1741 PFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEF 1800
PFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEF
Sbjct: 1741 PFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEF 1800
Query: 1801 VSRTLTTSGTLSTHMDQQFFQT 1822
VSRTLTTSGTLSTHMDQQFFQT
Sbjct: 1801 VSRTLTTSGTLSTHMDQQFFQT 1822
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 3489 bits (9048), Expect = 0.0
Identities = 1723/1824 (94%), Positives = 1728/1824 (94%), Gaps = 74/1824 (4%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG 1380
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT----------- 1369
Query: 1381 EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPP-- 1438
E L R+ + P G SL R T
Sbjct: 1370 EHLVNGRMDFAFP------------------------------GSTNSLHRMTTTSAAAY 1399
Query: 1439 GEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRS 1498
G HL S + HR+ +TS STLTRDYNSLTRS
Sbjct: 1400 GTHL-----------SPHVPHRVLSTS--------------------STLTRDYNSLTRS 1428
Query: 1499 EHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQ 1558
EHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQ
Sbjct: 1429 EHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQ 1488
Query: 1559 GYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI 1618
GYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI
Sbjct: 1489 GYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI 1548
Query: 1619 ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTC 1678
ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTC
Sbjct: 1549 ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTC 1608
Query: 1679 EMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD 1738
EMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD
Sbjct: 1609 EMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD 1668
Query: 1739 GGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQ 1798
GGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQ
Sbjct: 1669 GGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQ 1728
Query: 1799 EFVSRTLTTSGTLSTHMDQQFFQT 1822
EFVSRTLTTSGTLSTHMDQQFFQT
Sbjct: 1729 EFVSRTLTTSGTLSTHMDQQFFQT 1752
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 3465 bits (8984), Expect = 0.0
Identities = 1723/1877 (91%), Positives = 1728/1877 (92%), Gaps = 127/1877 (6%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
Sbjct: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR 60
Query: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
Sbjct: 61 CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL 120
Query: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
Sbjct: 121 EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV 180
Query: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
Sbjct: 181 PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL 240
Query: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
Sbjct: 241 QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR 300
Query: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
Sbjct: 301 TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE 360
Query: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
Sbjct: 361 EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG 420
Query: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
Sbjct: 421 THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV 480
Query: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
Sbjct: 481 CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN 540
Query: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
Sbjct: 541 FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR 600
Query: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
Sbjct: 601 CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE 660
Query: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
Sbjct: 661 LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL 720
Query: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
Sbjct: 721 LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR 780
Query: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
Sbjct: 781 SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC 840
Query: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
Sbjct: 841 AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK 900
Query: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
Sbjct: 901 LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL 960
Query: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
Sbjct: 961 LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG 1020
Query: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
Sbjct: 1021 KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH 1080
Query: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
Sbjct: 1081 VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS 1140
Query: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
Sbjct: 1141 RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG 1200
Query: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
Sbjct: 1201 AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV 1260
Query: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
Sbjct: 1261 NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP 1320
Query: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG 1380
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT
Sbjct: 1321 KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDT----------- 1369
Query: 1381 EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPP-- 1438
E L R+ + P G SL R T
Sbjct: 1370 EHLVNGRMDFAFP------------------------------GSTNSLHRMTTTSAAAY 1399
Query: 1439 GEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRS 1498
G HL S + HR+ +TS STLTRDYNSLTRS
Sbjct: 1400 GTHL-----------SPHVPHRVLSTS--------------------STLTRDYNSLTRS 1428
Query: 1499 EHSHSTTLPRDYSTLTSVSSH--------------------------------------- 1519
EHSHSTTLPRDYSTLTSVSSH
Sbjct: 1429 EHSHSTTLPRDYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDS 1488
Query: 1520 --------------DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQ 1565
DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQ
Sbjct: 1489 IILAGRPAAPSWGPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQ 1548
Query: 1566 LLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQ 1625
LLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQ
Sbjct: 1549 LLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQ 1608
Query: 1626 SPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGG 1685
SPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGG
Sbjct: 1609 SPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGG 1668
Query: 1686 PATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL 1745
PATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL
Sbjct: 1669 PATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL 1728
Query: 1746 GSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTL 1805
GSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTL
Sbjct: 1729 GSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTL 1788
Query: 1806 TTSGTLSTHMDQQFFQT 1822
TTSGTLSTHMDQQFFQT
Sbjct: 1789 TTSGTLSTHMDQQFFQT 1805
>gi|47078292 integrin beta chain, beta 3 precursor [Homo sapiens]
Length = 788
Score = 450 bits (1158), Expect = e-126
Identities = 272/761 (35%), Positives = 404/761 (53%), Gaps = 49/761 (6%)
Query: 2 AGPRPSP-WARLL-LAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFR-- 57
A PRP P WA +L L AL V + G N C V SC +C+ V CA+C+DE
Sbjct: 3 ARPRPRPLWATVLALGALAGVGVGGP--NICTTRGVSSCQQCLAVSPMCAWCSDEALPLG 60
Query: 58 DRRCNTQAELLAAGCQRESIVVMESSFQITEETQIDT-----TLRRSQMSPQGLRVRLRP 112
RC+ + LL C ESI S ++ E+ + + + +Q+SPQ + +RLRP
Sbjct: 61 SPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRP 120
Query: 113 GEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFG 172
+ ++F ++V + + PVD+Y LMD S SM DDL +++ +G LA + +LTS+ IGFG
Sbjct: 121 DDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFG 180
Query: 173 KFVDKVSVPQTDMRP-EKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISG 227
FVDK P + P E L+ P + P F +K+V++LT+ V F +++ + +S
Sbjct: 181 AFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSR 240
Query: 228 NLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDER 287
N DAPEGGFDAI+Q VC IGWR D++HLLVF+T++ H DG LAGI+ ND +
Sbjct: 241 NRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGR--LAGIVQPNDGQ 298
Query: 288 CHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGV 347
CH+ + Y+ T DYPS+ + L++ NI IFAVT + Y+ P +++GV
Sbjct: 299 CHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGV 358
Query: 348 LQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKT----RTGSFHIRRG 403
L DSSN+++L+ +A+ +IRS +++ D P L + ++ G
Sbjct: 359 LSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIG 418
Query: 404 EVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKE 462
+ + ++ + V P++++ + +KP F D L + CD C C+ Q E
Sbjct: 419 DTVSFSIEAK---------VRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCD-CACQAQAE 468
Query: 463 VRSARCSF-NGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGEC 518
S RC+ NG F CG C C GW G C CS Q REG+ CS RGEC
Sbjct: 469 PNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPV-CSQRGEC 527
Query: 519 QCGHCVCYGE--GRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCP 576
CG CVC+ G+ G++CE D+F C R G +C+ G+CS G C+C+ WTG C+C
Sbjct: 528 LCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCT 587
Query: 577 LSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQ 636
TC+ SNG +C+GRG CECG C C Q Y DT CE P C + CV+C+
Sbjct: 588 TRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDT-CE--KCPTCPDACTFKKECVECK 644
Query: 637 AWGTGE-KKGRTCEE-CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGP 694
+ G TC C +++ V ELK + V C++++E DDC + D +
Sbjct: 645 KFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNE-DDCVVRFQYYEDSS--G 701
Query: 695 NSTVLVHKKKDCPPGSFWWLIPLLLL-LLPLLALLLLLCWK 734
S + V ++ +CP G ++ L ++ + L+ L LL WK
Sbjct: 702 KSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWK 742
>gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens]
Length = 825
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743815 integrin beta 1 isoform 1B precursor [Homo sapiens]
Length = 789
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743813 integrin beta 1 isoform 1A precursor [Homo sapiens]
Length = 798
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743823 integrin beta 1 isoform 1A precursor [Homo sapiens]
Length = 798
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens]
Length = 819
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|19743819 integrin beta 1 isoform 1D precursor [Homo sapiens]
Length = 801
Score = 447 bits (1149), Expect = e-125
Identities = 273/749 (36%), Positives = 396/749 (52%), Gaps = 63/749 (8%)
Query: 28 NRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR------RCNTQAELLAAGCQRESIVVME 81
NRC KA KSC EC++ +C +CT+ F RC+ L GC + I
Sbjct: 25 NRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPR 84
Query: 82 SSFQITEETQIDTTLRRS----------QMSPQGLRVRLRPGEERHFELEVFEPLESPVD 131
S I + + + + Q+ PQ L +RLR GE + F L+ + P+D
Sbjct: 85 GSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPID 144
Query: 132 LYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLK 191
LY LMD S SM DDL+N+K +G +L + ++TSD+ IGFG FV+K +P P KL+
Sbjct: 145 LYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLR 204
Query: 192 EPW---PNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRD 248
P N PFS+KNV+SLT + F + +RISGNLD+PEGGFDAI+Q AVC
Sbjct: 205 NPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSL 264
Query: 249 IGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVP 308
IGWR + T LLVFST++ FH+ DG L GI+ ND +CHL+ YT DYPS+
Sbjct: 265 IGWR-NVTRLLVFSTDAGFHFAGDGK--LGGIVLPNDGQCHLE-NNMYTMSHYYDYPSIA 320
Query: 309 TLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRS 368
LV+ L+++NI IFAVT Y++L P S++G L +SSN+++L+ +A+N + S
Sbjct: 321 HLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSS 380
Query: 369 NLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVD---GTHVCQ 425
+ + G+ ++ K + K GE G + + V +
Sbjct: 381 EVILENGKLSEGV--TISYKSYCKNGVNG----TGENGRKCSNISIGDEVQFEISITSNK 434
Query: 426 LPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC-SFNGDFVCGQCVCSE 483
P+ + ++P F++ +++ IC+ C C+ + S +C NG F CG C C+E
Sbjct: 435 CPKKDSDSFKIRPLGFTEEVEVILQYICE-CECQSEGIPESPKCHEGNGTFECGACRCNE 493
Query: 484 GWSGQTCNCSTGSLSDIQP---CLREGEDKPCSGRGECQCGHCVCYGEGR----YEGQFC 536
G G+ C CST ++ C +E + CS GEC CG CVC Y G+FC
Sbjct: 494 GRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFC 553
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
E DNF C R++G +C G C C C P +TG +CDC L +TC SNG ICNGRG C
Sbjct: 554 ECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGIC 613
Query: 597 ECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNF--- 653
ECG C C T CE+ + + G+C + + CVQC+A+ GEKK +EC++
Sbjct: 614 ECGVCKCTDPKFQGQT-CEMCQTCL--GVCAEHKECVQCRAFNKGEKKDTCTQECSYFNI 670
Query: 654 -KVKMVDELKR--AEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCPP 708
KV+ D+L + + V C +D DDC + +T +G N+ V+VH + +CP
Sbjct: 671 TKVESRDKLPQPVQPDPVSHCKEKDV-DDCWFYFTYSVNG----NNEVMVHVVENPECPT 725
Query: 709 GSFWWLIPL---LLLLLPLLALLLLLCWK 734
G +IP+ ++ + L+ L LLL WK
Sbjct: 726 GPD--IIPIVAGVVAGIVLIGLALLLIWK 752
>gi|20127446 integrin, beta 5 [Homo sapiens]
Length = 799
Score = 436 bits (1120), Expect = e-121
Identities = 273/768 (35%), Positives = 390/768 (50%), Gaps = 68/768 (8%)
Query: 6 PSP-WARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRD-----R 59
P+P +A LL + L+G N C SC EC+ + CA+C+ E F
Sbjct: 5 PAPLYACLLGLCALLPRLAGL--NICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITS 62
Query: 60 RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRS------QMSPQGLRVRLRPG 113
RC+ +A L+ GC E I SSF + + + S QM+PQ + V LRPG
Sbjct: 63 RCDLRANLVKNGCGGE-IESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPG 121
Query: 114 EERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGK 173
++ F+L+V + + PVDLY LMD S SM DDLDN++ +G LA + +LTS++ +GFG
Sbjct: 122 DKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGS 181
Query: 174 FVDKVSVPQTDMRPEKLKEP------WPNSDPPFSFKNVISLTEDVDEFRNKLQGERISG 227
FVDK P + P P +PN P F F++++ LT+ VD F +++ +R+S
Sbjct: 182 FVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSR 241
Query: 228 NLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDER 287
N DAPEGGFDA+LQ AVC IGWR D+ HLLVF+T+ H DG L G++ +D +
Sbjct: 242 NRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGK--LGGLVQPHDGQ 299
Query: 288 CHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGV 347
CHL+ YT DYPS+ L LA++NI IFAVT Y Y+ P +++ +
Sbjct: 300 CHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEI 359
Query: 348 LQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVT-------SKMFQKTRTGSFHI 400
L DS NI++L+ A+N IRS +++ D P L T S Q+ G +
Sbjct: 360 LDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEG---L 416
Query: 401 RRGEVGIYQVQLRA-------LEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIIC 452
+ G+ ++V L A EHV L+P F D L++ C
Sbjct: 417 KIGDTASFEVSLEARSCPSRHTEHV---------------FALRPVGFRDSLEVGVTYNC 461
Query: 453 DVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDI-QPCLREGEDKP 511
C C + E SARC+ +G +VCG C CS G+ G C C G + Q RE E KP
Sbjct: 462 -TCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKP 520
Query: 512 -CSGRGECQCGHCVCYGE--GRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGW 568
CSGRG+C C C C+ G+ G FCE DNF C R G LC+ G C G+C C G+
Sbjct: 521 LCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGY 580
Query: 569 TGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCED 628
G +C+C +TC +G IC+ RGHC CG+C C + + + +CE P C
Sbjct: 581 IGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEPGAFGE-MCE--KCPTCPDACST 637
Query: 629 LRSCVQCQAWGTGEKKGRTCEE-CNFKV-KMVDELKRAEEVVVRCSFRDEDDDCTYSYTM 686
R CV+C +G+ +TC C +V VD + + ++ V C ++ DC +T
Sbjct: 638 KRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTA-KDCVMMFTY 696
Query: 687 EGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLLLLPLLALLLLLCWK 734
+ N TVL + P + L+ ++ +L L+ L LL WK
Sbjct: 697 VELPSGKSNLTVLREPECGNTPNAMTILLAVVGSIL-LVGLALLAIWK 743
>gi|9625002 integrin, beta 6 [Homo sapiens]
Length = 788
Score = 433 bits (1113), Expect = e-121
Identities = 248/733 (33%), Positives = 385/733 (52%), Gaps = 52/733 (7%)
Query: 30 CKKAPVKSCTECVRVDKDCAYCTDEMFRD-----RRCNTQAELLAAGCQRESIVVMESSF 84
C ++C +C+ + CA+C E F RC+T A LLA GCQ I S
Sbjct: 23 CALGGAETCEDCLLIGPQCAWCAQENFTHPSGVGERCDTPANLLAKGCQLNFIENPVSQV 82
Query: 85 QITEETQIDTTLRRS-----QMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFS 139
+I + + +++ Q++PQ L ++LRPG + ++ V + + PVDLY LMD S
Sbjct: 83 EILKNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLYYLMDLS 142
Query: 140 NSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWPNSD- 198
SM DDL+ +K++G L++ +S+LTS++ +GFG FV+K P PE++ P +
Sbjct: 143 ASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPY 202
Query: 199 ---PPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDS 255
P F FK+++ LT D + F ++ ++IS N+D PEGGFDAI+Q AVC IGWR DS
Sbjct: 203 FCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDS 262
Query: 256 THLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLA 315
HLLVF +++ H+ D LAGI+ ND CHLD+ Y+ +YP++ L+ L
Sbjct: 263 LHLLVFVSDADSHFGMDSK--LAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLV 320
Query: 316 KHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLDIRAL 375
++N++ IFAVT YE P +++G+LQ+DS NI++L+ A+ +RS +++ L
Sbjct: 321 QNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVL 380
Query: 376 DSPRGLRTEVTS-----KMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQ 430
GL T+ +FQ + S H++ G+ + V + + H E +
Sbjct: 381 GDTEGLNLSFTAICNNGTLFQHQKKCS-HMKVGDTASFSVTVN-IPHC---------ERR 429
Query: 431 KGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARCSF-NGDFVCGQCVCSEGWSGQ 488
+I +KP D L++ C+ C C+ + EV S++C NG F CG C C G G
Sbjct: 430 SRHIIIKPVGLGDALELLVSPECN-CDCQKEVEVNSSKCHHGNGSFQCGVCACHPGHMGP 488
Query: 489 TCNCSTGSLSDIQPCLREGEDKP-CSGRGECQCGHCVCYGE--GRYEGQFCEYDNFQCPR 545
C C LS +E D P CSGRG+C CG C+C+ G G +C+ DNF C R
Sbjct: 489 RCECGEDMLST--DSCKEAPDHPSCSGRGDCYCGQCICHLSPYGNIYGPYCQCDNFSCVR 546
Query: 546 TSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQ 605
G LC G C G+CVC GWTG C+C S +C+ +G +C+GRG C CG+C C
Sbjct: 547 HKGLLCGGNGDCDCGECVCRSGWTGEYCNCTTSTDSCVSEDGVLCSGRGDCVCGKCVCTN 606
Query: 606 QSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDELKR-A 664
T CE + P C RSC++C G+ + ++C + E + +
Sbjct: 607 PGASGPT-CERCPTCGDP--CNSKRSCIECHLSAAGQAREECVDKCKLAGATISEEEDFS 663
Query: 665 EEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVH--KKKDCP-PGSFWWLIPLLLLL 721
++ V CS + E ++C ++ + D ++H +KDCP P + ++ + L
Sbjct: 664 KDGSVSCSLQGE-NECLITFLITTDN----EGKTIIHSINEKDCPKPPNIPMIMLGVSLA 718
Query: 722 LPLLALLLLLCWK 734
+ L+ ++LL WK
Sbjct: 719 ILLIGVVLLCIWK 731
>gi|188595677 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 394 bits (1012), Expect = e-109
Identities = 273/805 (33%), Positives = 399/805 (49%), Gaps = 73/805 (9%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR- 59
M G RP LLA + +SL L+ C K V SC EC+ C +C F
Sbjct: 1 MLGLRPP-----LLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPG 55
Query: 60 -----RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGE 114
RC+T+ +LL GC + I+ S ETQ D + Q+SPQ + + LRPG+
Sbjct: 56 DPDSIRCDTRPQLLMRGCAADDIMDPTS----LAETQEDHNGGQKQLSPQKVTLYLRPGQ 111
Query: 115 ERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKF 174
F + P+DLY LMD S SM DDL N+KK+G +L R L+++T IGFG F
Sbjct: 112 AAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSF 171
Query: 175 VDKVSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLD 230
VDK +P + P+KL+ P PN + PPF+F++V+ LT + ++F+ ++ + ISGNLD
Sbjct: 172 VDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLD 231
Query: 231 APEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHL 290
APEGG DA++Q A C +IGWR + T LLVF+T+ FH+ DG L I++ ND RCHL
Sbjct: 232 APEGGLDAMMQVAACPEEIGWR-NVTRLLVFATDDGFHFAGDGK--LGAILTPNDGRCHL 288
Query: 291 DTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQE 350
+ Y + DYPSV L LA++NI PIFAVT+ YEKL P S++G L E
Sbjct: 289 E-DNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSE 347
Query: 351 DSSNIVELLEEAFNRIRSN--LDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIY 408
DSSN+V+L++ A+N++ S LD AL +VT F + RG+
Sbjct: 348 DSSNVVQLIKNAYNKLSSRVFLDHNALPD----TLKVTYDSFCSNGVTHRNQPRGDCDGV 403
Query: 409 QVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARC 468
Q+ + V T + ++Q I F+D + + C+ C C Q RS C
Sbjct: 404 QINVPITFQVKVT-ATECIQEQSFVIRAL-GFTDIVTVQVLPQCE-CRCRDQSRDRSL-C 459
Query: 469 SFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQ---PCLREGEDKPCSGRGECQCGHCVC 525
G CG C C G+ G+ C C T S + C ++ CSG G+C CG C+C
Sbjct: 460 HGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLC 519
Query: 526 Y-----GEGRYEGQFCEYDNFQCPRTSGFLCN--DRGRCSMGQCVCEPGWTGPSCDCPLS 578
+ G+ Y GQ+CE D C R +G +C RG C G+C C PG+ G +C C +
Sbjct: 520 HTSDVPGKLIY-GQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERT 578
Query: 579 NATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAW 638
C++ C+GRG C C C CH S Y +C+ P C SC +C +
Sbjct: 579 TEGCLNPRRVECSGRGRCRCNVCECH--SGYQLPLCQECPGC--PSPCGKYISCAECLKF 634
Query: 639 GTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTME-GDGAPGPNST 697
G G+ C +++ + + C RD + C +YT+E DG
Sbjct: 635 EKG-PFGKNCSAACPGLQLSNNPVKGR----TCKERD-SEGCWVAYTLEQQDGM--DRYL 686
Query: 698 VLVHKKKDCPPG-SFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVG 756
+ V + ++C G + ++ + + L+ +LLL+ WK AL+ H+
Sbjct: 687 IYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWK---------ALI------HLSD 731
Query: 757 FKEDHYMLRENLMASDHLDTPMLRS 781
+E +E L + + D P+ +S
Sbjct: 732 LREYRRFEKEKLKSQWNNDNPLFKS 756
>gi|89191865 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 394 bits (1012), Expect = e-109
Identities = 273/805 (33%), Positives = 399/805 (49%), Gaps = 73/805 (9%)
Query: 1 MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDR- 59
M G RP LLA + +SL L+ C K V SC EC+ C +C F
Sbjct: 1 MLGLRPP-----LLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPG 55
Query: 60 -----RCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGE 114
RC+T+ +LL GC + I+ S ETQ D + Q+SPQ + + LRPG+
Sbjct: 56 DPDSIRCDTRPQLLMRGCAADDIMDPTS----LAETQEDHNGGQKQLSPQKVTLYLRPGQ 111
Query: 115 ERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKF 174
F + P+DLY LMD S SM DDL N+KK+G +L R L+++T IGFG F
Sbjct: 112 AAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSF 171
Query: 175 VDKVSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLD 230
VDK +P + P+KL+ P PN + PPF+F++V+ LT + ++F+ ++ + ISGNLD
Sbjct: 172 VDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLD 231
Query: 231 APEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHL 290
APEGG DA++Q A C +IGWR + T LLVF+T+ FH+ DG L I++ ND RCHL
Sbjct: 232 APEGGLDAMMQVAACPEEIGWR-NVTRLLVFATDDGFHFAGDGK--LGAILTPNDGRCHL 288
Query: 291 DTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQE 350
+ Y + DYPSV L LA++NI PIFAVT+ YEKL P S++G L E
Sbjct: 289 E-DNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSE 347
Query: 351 DSSNIVELLEEAFNRIRSN--LDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIY 408
DSSN+V+L++ A+N++ S LD AL +VT F + RG+
Sbjct: 348 DSSNVVQLIKNAYNKLSSRVFLDHNALPD----TLKVTYDSFCSNGVTHRNQPRGDCDGV 403
Query: 409 QVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARC 468
Q+ + V T + ++Q I F+D + + C+ C C Q RS C
Sbjct: 404 QINVPITFQVKVT-ATECIQEQSFVIRAL-GFTDIVTVQVLPQCE-CRCRDQSRDRSL-C 459
Query: 469 SFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQ---PCLREGEDKPCSGRGECQCGHCVC 525
G CG C C G+ G+ C C T S + C ++ CSG G+C CG C+C
Sbjct: 460 HGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLC 519
Query: 526 Y-----GEGRYEGQFCEYDNFQCPRTSGFLCN--DRGRCSMGQCVCEPGWTGPSCDCPLS 578
+ G+ Y GQ+CE D C R +G +C RG C G+C C PG+ G +C C +
Sbjct: 520 HTSDVPGKLIY-GQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERT 578
Query: 579 NATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAW 638
C++ C+GRG C C C CH S Y +C+ P C SC +C +
Sbjct: 579 TEGCLNPRRVECSGRGRCRCNVCECH--SGYQLPLCQECPGC--PSPCGKYISCAECLKF 634
Query: 639 GTGEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTME-GDGAPGPNST 697
G G+ C +++ + + C RD + C +YT+E DG
Sbjct: 635 EKG-PFGKNCSAACPGLQLSNNPVKGR----TCKERD-SEGCWVAYTLEQQDGM--DRYL 686
Query: 698 VLVHKKKDCPPG-SFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVG 756
+ V + ++C G + ++ + + L+ +LLL+ WK AL+ H+
Sbjct: 687 IYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWK---------ALI------HLSD 731
Query: 757 FKEDHYMLRENLMASDHLDTPMLRS 781
+E +E L + + D P+ +S
Sbjct: 732 LREYRRFEKEKLKSQWNNDNPLFKS 756
>gi|4504777 integrin, beta 7 [Homo sapiens]
Length = 798
Score = 387 bits (995), Expect = e-107
Identities = 230/643 (35%), Positives = 327/643 (50%), Gaps = 48/643 (7%)
Query: 25 TLANRCKKAPVKSCTECVRVDKDCAYCTDEMF------RDRRCNTQAELLAAGCQRESIV 78
++ C+ AP SC +C+ CA+C F RRC + ELLA GC E +
Sbjct: 40 SMLGSCQPAP--SCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPLEELE 97
Query: 79 VMESSFQITEETQIDTTLR---RSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYIL 135
++ ++ + R +Q++PQ +RV LRPGE + ++ PVDLY L
Sbjct: 98 EPRGQQEVLQDQPLSQGARGEGATQLAPQRVRVTLRPGEPQQLQVRFLRAEGYPVDLYYL 157
Query: 136 MDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWP 195
MD S SM DDL+ ++++G L L ++T IGFG FVDK +P P KL+ P P
Sbjct: 158 MDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLRHPCP 217
Query: 196 NS----DPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGW 251
PFSF +V+SLT D F ++ + +SGNLD+PEGGFDAILQ A+C IGW
Sbjct: 218 TRLERCQSPFSFHHVLSLTGDAQAFEREVGRQSVSGNLDSPEGGFDAILQAALCQEQIGW 277
Query: 252 RPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLV 311
R + + LLVF+++ FH DG L GI +D CHLD+ G Y++ DYPSV +
Sbjct: 278 R-NVSRLLVFTSDDTFHTAGDGK--LGGIFMPSDGHCHLDSNGLYSRSTEFDYPSVGQVA 334
Query: 312 RLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLD 371
+ L+ NI PIFAVT+ + Y++L P S++G L EDSSN+V+L+ +A+N + S +
Sbjct: 335 QALSAANIQPIFAVTSAALPVYQELSKLIPKSAVGELSEDSSNVVQLIMDAYNSLSSTVT 394
Query: 372 IRALDSPRGLRTEVTSKM--------FQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHV 423
+ P G+ S+ + R H+R + + V L+A + H+
Sbjct: 395 LEHSSLPPGVHISYESQCEGPEKREGKAEDRGQCNHVRINQTVTFWVSLQATHCLPEPHL 454
Query: 424 CQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCS-FNGDFVCGQCVCS 482
+L FS+ L ++ +CD C C + ++ CS G CG C C+
Sbjct: 455 LRL---------RALGFSEELIVELHTLCD-CNCS-DTQPQAPHCSDGQGHLQCGVCSCA 503
Query: 483 EGWSGQTCNCSTGSLS--DIQPCLR--EGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEY 538
G G+ C CS LS D++ R G CSG+G CQCG C C G+ G CE
Sbjct: 504 PGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQS--SGHLCEC 561
Query: 539 DNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCEC 598
D+ C R G LC GRC G C C TG +C+C +CI GG+C+G G C+C
Sbjct: 562 DDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKC 621
Query: 599 GRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTG 641
RC C Y +C+ P CE R C +C A+ TG
Sbjct: 622 NRCQCLDG--YYGALCDQCPGCKTP--CERHRDCAECGAFRTG 660
>gi|4504779 integrin, beta 8 precursor [Homo sapiens]
Length = 769
Score = 323 bits (827), Expect = 1e-87
Identities = 207/700 (29%), Positives = 338/700 (48%), Gaps = 67/700 (9%)
Query: 3 GPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMF-----R 57
GP WA + + ++ + NRC + SC C+ + +C +C E F R
Sbjct: 22 GPASFLWAAWVFSLVLGLGQGED--NRCASSNAASCARCLALGPECGWCVQEDFISGGSR 79
Query: 58 DRRCNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERH 117
RC+ + L++ GC +SI I E +I+T Q++P + ++LRPG E +
Sbjct: 80 SERCDIVSNLISKGCSVDSIEYPSVHVIIPTENEINT-----QVTPGEVSIQLRPGAEAN 134
Query: 118 FELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDK 177
F L+V + PVDLY L+D S SM ++++ L +G +L+R ++ + D+ +GFG +VDK
Sbjct: 135 FMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDK 194
Query: 178 VSVPQTDMRPEKLKEPWPNSD----PPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPE 233
P + PE++ + + PP + +V+SLTE++ EF + ++ISGN+D PE
Sbjct: 195 TVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPE 254
Query: 234 GGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTT 293
GGFDA+LQ AVC IGWR ++ LL+ T+ H D + LAGI+ ND CHL
Sbjct: 255 GGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALD--SKLAGIVVPNDGNCHL-KN 311
Query: 294 GTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSS 353
Y + T ++PS+ L L +NI IFAV + +Y+ L P + G ++ ++
Sbjct: 312 NVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAA 371
Query: 354 NIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTR----TGSFHIRRGEVGIYQ 409
N+ L+ EA+ ++ S + ++ + +G+ +T+ +R G ++ + ++
Sbjct: 372 NLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRKPGMEGCRNVTSNDEVLFN 431
Query: 410 VQLRALEHVDGTHVCQLPEDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARC 468
V + ++ D T K +KP F++ K+ C C CE + + +C
Sbjct: 432 VTV-TMKKCDVT-------GGKNYAIIKPIGFNETAKIHIHRNCS-CQCEDNRGPK-GKC 481
Query: 469 SFNGDFVCGQCV-CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCY- 526
+ F+ +C C E C+ S + C + CSGRG C CG C C+
Sbjct: 482 -VDETFLDSKCFQCDE----NKCHFDEDQFSS-ESCKSHKDQPVCSGRGVCVCGKCSCHK 535
Query: 527 -GEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNAT-CID 584
G+ G++CE D+F CP G LC G C G+C C GW G C CP + A C++
Sbjct: 536 IKLGKVYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVN 595
Query: 585 SNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKK 644
S G +C+GRG C CGRC C R C C T K+
Sbjct: 596 SKGQVCSGRGTCVCGRCECTDPRSIG-------------------RFCEHCPTCYTACKE 636
Query: 645 GRTCEEC----NFKVKMVDELKRAEEVVVRCSFRDEDDDC 680
C +C N ++D+ K + ++ + + D+ +C
Sbjct: 637 NWNCMQCLHPHNLSQAILDQCKTSCALMEQQHYVDQTSEC 676
>gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains)
[Homo sapiens]
Length = 494
Score = 140 bits (352), Expect = 1e-32
Identities = 76/224 (33%), Positives = 107/224 (47%), Gaps = 31/224 (13%)
Query: 453 DVCTCELQKEVRSAR-------CSFNGDFVCGQCVCSEGWSGQTC----NCSTGSLSDIQ 501
D C C+ +++ R+ CS +G CG+C C GW G+ C +C+ + I+
Sbjct: 267 DTCECD-ERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIR 325
Query: 502 PCLREGEDKPCSGRGECQCGHCVCY--GEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSM 559
C + D PCSGRG+C+CG C CY G+ R G+ CE D+ +C G +C G CS
Sbjct: 326 KC-QGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSC 384
Query: 560 GQCVCEPGWTGPSCDCP--------LSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTD 611
G+CVCE GW G C P S C ++G +C+G+G C CG+C C + Y
Sbjct: 385 GRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYIS 444
Query: 612 ---TICEINYSAIHPGLC---EDLRSCVQCQAWGTGEKKGRTCE 649
C+ H GL + SC C+ W G CE
Sbjct: 445 GEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGW--NGNACE 486
Score = 114 bits (286), Expect = 7e-25
Identities = 66/196 (33%), Positives = 85/196 (43%), Gaps = 25/196 (12%)
Query: 452 CDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTC----NCSTGSLSDIQPCLREG 507
C CE + C+ +G CG+C C +GW G C NC Q C +
Sbjct: 91 CHEWVCETYD---GSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMC-KNS 146
Query: 508 EDKPCSGRGECQCGHCVCY---GEGRYEGQFCEYDNFQC-PRTSGFLCNDRGRCSMGQCV 563
+D CS G C CG C C G G G+FCE D+ +C + +C G+C G C
Sbjct: 147 QDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCY 206
Query: 564 CEPGWTGPSCD--CPL----SNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEIN 617
C+ GW G C+ C + S C +G IC+ RG C CG C CH D
Sbjct: 207 CKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGD------ 260
Query: 618 YSAIHPGLCE-DLRSC 632
+ IH CE D R C
Sbjct: 261 WGDIHGDTCECDERDC 276
Score = 108 bits (271), Expect = 4e-23
Identities = 74/232 (31%), Positives = 94/232 (40%), Gaps = 31/232 (13%)
Query: 441 SDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTC--NCSTGSLS 498
SDG + G C+ E + C +G CG C C GW G C C
Sbjct: 167 SDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWE 226
Query: 499 DIQPCLREGEDKPCSGRGECQCGHCVCYGE------GRYEGQFCEYDNFQC----PRTSG 548
+ C + K CS RG C CG C C+ G G CE D C R S
Sbjct: 227 SKRRC-TSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSD 285
Query: 549 FLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNA--------TCIDSNGGICNGRGHCECGR 600
C+ G+C+ G+C C+ GW G C+ P S C S+ C+GRG CECG+
Sbjct: 286 DFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGK 345
Query: 601 CHCH---QQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCE 649
C C+ + +Y T CE + CEDL V C GT CE
Sbjct: 346 CTCYPPGDRRVYGKT-CECD-----DRRCEDLDGVV-CGGHGTCSCGRCVCE 390
Score = 90.9 bits (224), Expect = 1e-17
Identities = 45/132 (34%), Positives = 57/132 (43%), Gaps = 15/132 (11%)
Query: 485 WSGQTCNCSTGSLSDIQPCLREGEDKP---CSGRGECQCGHCVCY--GEGRYEGQFCEYD 539
W G C S + C G+ C GRG C CG C+C+ G + G CE
Sbjct: 35 WPGAACRLSRAESE--RRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECH 92
Query: 540 NFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL--------SNATCIDSNGGICN 591
+ C G C G+C G+C C+ GW G +C P SN C +S IC+
Sbjct: 93 EWVCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICS 152
Query: 592 GRGHCECGRCHC 603
G C CGRC C
Sbjct: 153 NAGTCHCGRCKC 164
Score = 59.7 bits (143), Expect = 3e-08
Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 550 LCNDRGRCSMGQCVC---EPG-WTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQ 605
LC+ RGRC G C+C EPG + GP C+C C +G C G G C+CG+C C Q
Sbjct: 62 LCHGRGRCDCGVCICHVTEPGMFFGPLCEC--HEWVCETYDGSTCAGHGKCDCGKCKCDQ 119
Score = 35.4 bits (80), Expect = 0.51
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGS 496
C+ NG CG C C +GW+G C GS
Sbjct: 463 CTGNGICSCGNCECWDGWNGNACEIWLGS 491
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 106 bits (265), Expect = 2e-22
Identities = 157/669 (23%), Positives = 254/669 (37%), Gaps = 100/669 (14%)
Query: 1129 APQNPNAKAAGSRKIHFNWLP-----PSGKPMGYRVKYWIQG-DSESEAHLL-DSKVPSV 1181
AP+N +A+A S +I W +G +GY++ + + D E +H++ + S
Sbjct: 1279 APENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSA 1338
Query: 1182 ELTNLYPYCDYEMKVCAYGAQGEG-PYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
L L + YE++V A+ G G P + L+ RT + P P RL F V T ++ W
Sbjct: 1339 LLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVW 1398
Query: 1241 AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
P E NG I Y++ Y L + ++ R +L Y + + A
Sbjct: 1399 QPPEEPNGIILGYQIAYRLASSSPHTFTTVEV----GATVRQFTATDLAPESAYIFRLSA 1454
Query: 1301 RNGAGWGPEREAIINLATQPKRPMSIP----IIPD------------IPIVDAQSGEDYD 1344
+ GWG EA + T KR P ++P +P D S Y
Sbjct: 1455 KTRQGWGEPLEATV--ITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRY- 1511
Query: 1345 SFLMYSDDVLRSPSGSQRPSVSDD-TGCGW-KFEPLLGEELDLRRVTWRLPPELIPRLSA 1402
F M ++ R + S+S + T C + P +L L+
Sbjct: 1512 -FTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKAT----------NDIG 1560
Query: 1403 SSGRSSDAEAPHGPPD-DGGAGGKGGSLPRSATP-----GPPGEHLVNGRMDFAFPGSTN 1456
S SS+ EA D G G + P + + PP + +NG +
Sbjct: 1561 DSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLL------QGY 1614
Query: 1457 SLHRMTTTSAAAYGTHL----SPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLP--RDY 1510
++ A GT +P H L+ S+ + NS + S T L R Y
Sbjct: 1615 RIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSF-KTVNSSSTSTMCELTHLKKYRRY 1673
Query: 1511 STLTSVSSHDSRLTAGVP-----------DTPTRLVFSALGPTSLRVSWQEPRCERP--- 1556
+ + + A P P + + L + L V+W P E
Sbjct: 1674 EVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGN 1733
Query: 1557 LQGYSVEY-QLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGV 1615
+QGY + Y + + E ++ + + V +++L + Y+ + A + G G + +
Sbjct: 1734 IQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSD-- 1791
Query: 1616 ITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYL 1675
P G + P AP L F+ ++ +L +SW P NG + GY
Sbjct: 1792 --------------PQQGRTHQ-AAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYR 1836
Query: 1676 VTCE---MAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGII 1732
V E QG V G+ + L V L++ V Y F+VQART +GPE + I
Sbjct: 1837 VVYEPLAPVQGVSKVVTVEVRGNW-QRWLKVRDLTKGVTYFFRVQARTIT-YGPELQANI 1894
Query: 1733 TIESQDGGP 1741
T +G P
Sbjct: 1895 TAGPAEGSP 1903
Score = 97.4 bits (241), Expect = 1e-19
Identities = 67/208 (32%), Positives = 98/208 (47%), Gaps = 17/208 (8%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAH---LLDSKVPS 1180
APQN + ++ W PP +G GY++ YW + DS++E +L P
Sbjct: 1704 APQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYW-EADSQNETEKMKVLFLPEPV 1762
Query: 1181 VELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
V L NL + Y + + A+ A G+GP S RTHQ P P LAF+ ++ST +SW
Sbjct: 1763 VRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSW 1822
Query: 1241 AEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVL---VDNPKNRMLLIENLRESQPYRYT 1297
EPA NG + Y V Y + P+ + KV+ V R L + +L + Y +
Sbjct: 1823 GEPAAANGILQGYRVVY----EPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFR 1878
Query: 1298 VKARNGAGWGPEREAIINLATQPKRPMS 1325
V+AR +GPE +A I P S
Sbjct: 1879 VQART-ITYGPELQANITAGPAEGSPGS 1905
Score = 79.0 bits (193), Expect = 4e-14
Identities = 141/656 (21%), Positives = 240/656 (36%), Gaps = 95/656 (14%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPP-----SGKP--MGYRVKYWIQGDSESEAH---LLDSKV 1178
AP + + A + W+P +G P +GYR+KYW + D +S A + D
Sbjct: 1176 APTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYW-RSDLQSSAVAQVVSDRLE 1234
Query: 1179 PSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQ 1237
+ L + +YE+++ A+ A G GP+S +V RT + VPS P ++ VSST
Sbjct: 1235 REFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQIL 1294
Query: 1238 LSWAEPAE--TNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
L+W E NG I Y++ + + D P + +V + L+ LR+ Y
Sbjct: 1295 LTWTSVPEQDQNGLILGYKILFRAKDLDPEP----RSHIVRGNHTQSALLAGLRKFVLYE 1350
Query: 1296 YTVKARNGAGWGPEREAIINLATQ---PKRPMSIPIIPDIPIVDA----QSGEDYDSFLM 1348
V A G G +I T+ P P+ + + P++ + Q E+ + ++
Sbjct: 1351 LQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRL-VFPEVRLTSVRIVWQPPEEPNGIIL 1409
Query: 1349 YSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSS 1408
R S S + + G +R+ T +L P + S+
Sbjct: 1410 GYQIAYRLASSSPHTFTTVEVGA------------TVRQFT---ATDLAPESAYIFRLSA 1454
Query: 1409 DAEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLV--------NGRMDFAFPGS------ 1454
G P + + + P PP E LV + R+ + PGS
Sbjct: 1455 KTRQGWGEPLEATV----ITTEKRERPAPPRELLVPQAEVTARSLRLQWV-PGSDGASPI 1509
Query: 1455 ---TNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLT------RDYNSLTRSEHSHSTT 1505
T + + Y + +S V+ T + N + S+ S T
Sbjct: 1510 RYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSET- 1568
Query: 1506 LPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCER---PLQGYSV 1562
+TL V + P T +S+ + WQ PR E LQGY +
Sbjct: 1569 --EAVTTLQDVPGEPPGSVSATPHT----------TSSVLIQWQPPRDESLNGLLQGYRI 1616
Query: 1563 -----EYQLLNGGELHRLNIPNPAQTSVVVEDLLP--NHSYVFRVRAQSQEGWGREREGV 1615
EY+ +G E L P + + N S + + R E +
Sbjct: 1617 YYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVI 1676
Query: 1616 ITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWE--RPRRPNGDIVG 1673
+T + + P+ + AP + T L+ L+++W+ P NG+I G
Sbjct: 1677 MTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQG 1736
Query: 1674 YLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPERE 1729
Y + A +V PE + + L+ + Y + A G GP+ +
Sbjct: 1737 YKIYYWEADSQNETEKMKV-LFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSD 1791
Score = 67.4 bits (163), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 16/204 (7%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSK----VPS 1180
PQN +A S I F W PP +G GY++ W E+ + + V
Sbjct: 873 PQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHH 932
Query: 1181 VELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSW 1240
+TNL + Y V + G+GP S+ T ++ P G L+F + T ++SW
Sbjct: 933 GHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSW 992
Query: 1241 AEPAETNGEITAYEVCYGLV-NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVK 1299
EP E NG IT Y++ + + +D+R + N I+ L Y V
Sbjct: 993 QEPLEKNGIITGYQISWEVYGRNDSRLTHTL------NSTTHEYKIQGLSSLTTYTIDVA 1046
Query: 1300 ARNGAGWGPEREAIINLATQPKRP 1323
A G G + I+ P P
Sbjct: 1047 AVTAVGTGLVTSSTISSGVPPDLP 1070
Score = 55.8 bits (133), Expect = 4e-07
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 20/208 (9%)
Query: 1123 PHGDLGAPQNPNAKAAGSRKIHFNWLPP--SGKPMGYRVKYWIQGDSESEAHL--LDSKV 1178
PH +PN+ + S + +W+ P P+ Y + + +S + HL + ++
Sbjct: 668 PHSPQNLLVSPNS--SHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEM 725
Query: 1179 PSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVS-CRTHQEVPSEPGRLAFNVVSSTVTQ 1237
V ++ L P Y+ +VCA G G YS+ S +E PS P + N+V+S T
Sbjct: 726 TGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPK---NIVASGRTN 782
Query: 1238 LS----WAEPAET--NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRES 1291
S W P ET NG + Y + Y L G ++ + +P+ L+ +L
Sbjct: 783 QSIMVQWQPPPETEHNGVLRGYILRYRLAGLP----GEYQQRNITSPEVNYCLVTDLIIW 838
Query: 1292 QPYRYTVKARNGAGWGPEREAIINLATQ 1319
Y V A NGAG G A+ Q
Sbjct: 839 TQYEIQVAAYNGAGLGVFSRAVTEYTLQ 866
Score = 55.8 bits (133), Expect = 4e-07
Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 24/227 (10%)
Query: 1522 RLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP-LQGYSVEYQLL----NGGELHRLN 1576
R P P+ L FS + T+L VSW EP LQGY V Y+ L ++ +
Sbjct: 1796 RTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVE 1855
Query: 1577 IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF 1636
+ Q + V DL +Y FRV+A++ IT ++ P GS
Sbjct: 1856 VRGNWQRWLKVRDLTKGVTYFFRVQART-----------ITYGPELQANITAGPAEGS-- 1902
Query: 1637 TLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMA-QGGGPATAFRVDGD 1695
P +P ++ T S L L W + GY++ + +G +
Sbjct: 1903 ----PGSPRDVLVTK-SASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRS 1957
Query: 1696 SPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPF 1742
+ L++ L + V Y+F+V A G+G + +Q PF
Sbjct: 1958 ATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 2004
Score = 52.4 bits (124), Expect = 4e-06
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 1113 TSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQG-- 1165
TS+++ + PP P+N A ++ I W PP +G GY ++Y + G
Sbjct: 758 TSRLMLPEEPPSAP---PKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLP 814
Query: 1166 DSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR 1225
+ ++ +V +T+L + YE++V AY G G +S V+ T Q VP+ P +
Sbjct: 815 GEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQ 874
Query: 1226 -LAFNVVSSTVTQLSWAEPAE 1245
+ V+ST Q W P +
Sbjct: 875 NVQTEAVNSTTIQFLWNPPPQ 895
Score = 48.9 bits (115), Expect = 4e-05
Identities = 61/275 (22%), Positives = 101/275 (36%), Gaps = 37/275 (13%)
Query: 1484 TSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT----------- 1532
T T+ D++ + H H T L + + TSV + G P TP
Sbjct: 919 TVVTIAPDFHGV---HHGHITNLKKFTAYFTSVLCFTTP-GDGPPSTPQLVWTQEDKPGA 974
Query: 1533 --RLVFSALGPTSLRVSWQEPRCERPL-QGYSVEYQLLNGGELHRLNIPNPAQTSVVVED 1589
L F+ + TSL+VSWQEP + + GY + +++ + + N ++
Sbjct: 975 VGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQG 1034
Query: 1590 LLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVF 1649
L +Y V A + G G TI S V P P AP LV
Sbjct: 1035 LSSLTTYTIDVAAVTAVGTGLVTSS--TISSGVPPD--------------LPGAPSNLVI 1078
Query: 1650 TALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGP---ATAFRVDGDSPESRLTVPGL 1706
+ +SP S L + I ++V ++ G T + + + L +P L
Sbjct: 1079 SNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNL 1138
Query: 1707 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1741
+ Y+F+++ G P I++ P
Sbjct: 1139 TPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPP 1173
Score = 45.4 bits (106), Expect = 5e-04
Identities = 60/233 (25%), Positives = 86/233 (36%), Gaps = 27/233 (11%)
Query: 1113 TSQMLSSQPPPHGDL-GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQ------- 1164
TS +SS PP DL GAP N R + P G + WI
Sbjct: 1057 TSSTISSGVPP--DLPGAPSNLVISNISPRSATLQFRP--GYDGKTSISRWIVEGQVGAI 1112
Query: 1165 GDSESEAHLLDSK----VPSVELTNLYPYCDYEMKVCAYGAQGEGPYS-SLVSCRTHQEV 1219
GD E L + + +E+ NL PY Y ++ G PYS S +T Q
Sbjct: 1113 GDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAP 1172
Query: 1220 PS-EPGRLAFNVVSSTVTQLSWAEPAET----NGEITAYEVCYGLVNDDNRPIGPMKKVL 1274
P P + S T +L W ++ N E Y + Y + + + +
Sbjct: 1173 PDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQ----V 1228
Query: 1275 VDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
V + R IE L E Y ++A N G GP E ++ T+ P + P
Sbjct: 1229 VSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSE-VVRGRTRESVPSAAP 1280
Score = 45.1 bits (105), Expect = 6e-04
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 21/222 (9%)
Query: 1526 GVPDTPTRLVFS-ALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTS 1584
GVP P + V + A+ T+++ W P ++ + G + Y+LL P A +
Sbjct: 867 GVPTAPPQNVQTEAVNSTTIQFLWNPPP-QQFINGINQGYKLLAW--------PADAPEA 917
Query: 1585 VVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLST-PSA 1643
V V + P+ V + + + V+ + P P +T P A
Sbjct: 918 VTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTT---PGDGPPSTPQLVWTQEDKPGA 974
Query: 1644 PGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTV 1703
G L FT + SL++SW+ P NG I GY ++ E+ ++ + E + +
Sbjct: 975 VGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYK--I 1032
Query: 1704 PGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQL 1745
GLS Y V A T G G++T + G P L
Sbjct: 1033 QGLSSLTTYTIDVAAVTAVG-----TGLVTSSTISSGVPPDL 1069
Score = 31.6 bits (70), Expect = 7.4
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 1638 LSTPSAPGPLVFTALSPDS--LQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGD 1695
+ P +P L+ + S S + LSW RP N I+ Y+V E+++ P +
Sbjct: 665 IELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIV--ELSENNSPWKVHLSNVG 722
Query: 1696 SPESRLTVPGLSENVPYKFKVQARTTEGFG 1725
+ +TV GL+ Y+F+V A G G
Sbjct: 723 PEMTGVTVSGLTPARTYQFRVCAVNEVGRG 752
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 102 bits (255), Expect = 3e-21
Identities = 151/672 (22%), Positives = 249/672 (37%), Gaps = 84/672 (12%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 326 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 385
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 386 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 445
Query: 1248 GEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWG 1307
G+I Y V Y + D + + K V + +++ I NL + Y V A G G
Sbjct: 446 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD--SQITTIGNLVPQKTYSVKVLAFTSIGDG 501
Query: 1308 PEREAIINLATQ---PKRPMSIPIIPD--IPIVDAQSGEDYDSFLMYSDDVLRSPSGSQR 1362
P + I + TQ P +P++ P+ I+ + + D+ Y + V + +
Sbjct: 502 P-LSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANY-ELVYKDGEHGEE 559
Query: 1363 PSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGA 1422
++ + G ++ + L L R+ R P L + S R+ ++ P PP D
Sbjct: 560 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK-PSAPPQDISC 618
Query: 1423 GGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVL 1482
+ + PP E N + +T S PH +L
Sbjct: 619 TSPSSTSILVSWQPPPVE-------------KQNGI--ITEYSIKYTAVDGEDDKPHEIL 663
Query: 1483 STSSTLTR----------DYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT 1532
S T+ +Y +T + H+ P S L R VP P
Sbjct: 664 GIPSDTTKYLLEQLEKWTEYR-ITVTAHTDVGPGPESLSVLI-------RTNEDVPSGPP 715
Query: 1533 RLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELHRLNIPNPAQTS---- 1584
R V A+ TS++VSW+ P + ++GY V Y + GE + +
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQD 775
Query: 1585 VVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP 1644
+++ L P SY V A + +G G + + + P P
Sbjct: 776 MIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR---------------- 819
Query: 1645 GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVP 1704
LV ++ + W P G + GY + + P T ++ E T
Sbjct: 820 --LVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGR-KDMEPLTT--LEFSEKEDHFTAT 874
Query: 1705 GLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGL--------FQHPL 1756
+ + Y F++ AR GFG E I+I + FPQ G +Q P+
Sbjct: 875 DIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPV 934
Query: 1757 QSEYSSITTTHT 1768
+E + I T +T
Sbjct: 935 LAERNGIITKYT 946
Score = 61.2 bits (147), Expect = 9e-09
Identities = 69/242 (28%), Positives = 98/242 (40%), Gaps = 26/242 (10%)
Query: 1511 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1570
STL + + +P P V + TS+ ++W E P+ Y ++++ N
Sbjct: 306 STLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPE-PVSYYIIQHKPKNSE 364
Query: 1571 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1630
EL++ I A T V L P Y FRV A + G G E V+T S+ P S
Sbjct: 365 ELYK-EIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSS---- 419
Query: 1631 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPAT 1688
AP + LS ++ + W+ P PNG I GY V T + Q
Sbjct: 420 ------------APRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWM 467
Query: 1689 AFRVDGDSPESRLTVPG-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGS 1747
V +S++T G L Y KV A T+ G GP I I +Q G P L
Sbjct: 468 KHNV----ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVI-TQTGVPGQPLNF 522
Query: 1748 RA 1749
+A
Sbjct: 523 KA 524
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 19/229 (8%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 397 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 456
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 457 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 514
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 567
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 568 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP 613
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 905 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 964
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 965 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1024
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1025 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1073
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1074 FVLTNRGNSAGG 1085
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 1531 PTRLVFSALGPTSLRVSWQEP-RCERP--LQGYSVEYQLLNGGELHRLNIPNPAQTSVVV 1587
P L TS+++SWQ P ER + Y++ Y+ +N L + PA T++ +
Sbjct: 913 PQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTL 972
Query: 1588 EDLLPNHSYVFRVRAQSQEGWG 1609
L P+ +Y +VRA + +G G
Sbjct: 973 TGLKPDTTYDVKVRAHTSKGPG 994
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 102 bits (253), Expect = 4e-21
Identities = 151/681 (22%), Positives = 250/681 (36%), Gaps = 93/681 (13%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 326 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 385
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 386 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 445
Query: 1248 GEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWG 1307
G+I Y V Y + D + + K V + +++ I NL + Y V A G G
Sbjct: 446 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD--SQITTIGNLVPQKTYSVKVLAFTSIGDG 501
Query: 1308 PEREAIINLATQ---PKRPMSIPIIPD--IPIVDAQSGEDYDSFLMYSDDVLRSPSGSQR 1362
P + I + TQ P +P++ P+ I+ + + D+ Y + V + +
Sbjct: 502 P-LSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANY-ELVYKDGEHGEE 559
Query: 1363 PSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGA 1422
++ + G ++ + L L R+ R P L + S R+ ++ P PP D
Sbjct: 560 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK-PSAPPQDISC 618
Query: 1423 GGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVL 1482
+ + PP E N + +T S PH +L
Sbjct: 619 TSPSSTSILVSWQPPPVE-------------KQNGI--ITEYSIKYTAVDGEDDKPHEIL 663
Query: 1483 STSSTLTR----------DYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT 1532
S T+ +Y +T + H+ P S L R VP P
Sbjct: 664 GIPSDTTKYLLEQLEKWTEYR-ITVTAHTDVGPGPESLSVLI-------RTNEDVPSGPP 715
Query: 1533 RLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH-------------RL 1575
R V A+ TS++VSW+ P + ++GY V Y + GE +
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQW 775
Query: 1576 NIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSA 1635
+ + +++ L P SY V A + +G G + + + P P
Sbjct: 776 EFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR------- 828
Query: 1636 FTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGD 1695
LV ++ + W P G + GY + + P T ++
Sbjct: 829 -----------LVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGR-KDMEPLTT--LEFS 874
Query: 1696 SPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGL---- 1751
E T + + Y F++ AR GFG E I+I + FPQ G
Sbjct: 875 EKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTS 934
Query: 1752 ----FQHPLQSEYSSITTTHT 1768
+Q P+ +E + I T +T
Sbjct: 935 VQLSWQPPVLAERNGIITKYT 955
Score = 74.7 bits (182), Expect = 8e-13
Identities = 121/525 (23%), Positives = 198/525 (37%), Gaps = 81/525 (15%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
G P N A+ I +W PP + + G+ E + S L L
Sbjct: 517 GQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLK 576
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSWAEPA-- 1244
P Y ++ A QG G ++ +S RT Q PS P + ++ SST +SW P
Sbjct: 577 PNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVE 636
Query: 1245 ETNGEITAYEVCYGLVN-DDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNG 1303
+ NG IT Y + Y V+ +D++P ++L L+E L + YR TV A
Sbjct: 637 KQNGIITEYSIKYTAVDGEDDKP----HEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 692
Query: 1304 AGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQS----------GEDYDSFLMYSDDV 1353
G GPE +++ + T P P ++ V++ S + + Y
Sbjct: 693 VGPGPESLSVL-IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHY 751
Query: 1354 LRSPSGSQR--PSVSDD--TGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSD 1409
+R +G + P + D W+F+ ++ + L PE L+ ++ +
Sbjct: 752 VRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDM----IISGLQPETSYSLTVTAYTTKG 807
Query: 1410 AEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAY 1469
A P G A PG P + + +M+ A H T
Sbjct: 808 DGARSKPKLVSTTG---------AVPGKPRLVINHTQMNTALI----QWHPPVDTFGPLQ 854
Query: 1470 GTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSV---SSHDSRLTA- 1525
G L +D LT E S D+ T T + +S+ RL+A
Sbjct: 855 GYRLKFG------------RKDMEPLTTLEFSEK----EDHFTATDIHKGASYVFRLSAR 898
Query: 1526 -------------GVPDT-----PTRLVFSALGPTSLRVSWQEP-RCERP--LQGYSVEY 1564
+P+ P L TS+++SWQ P ER + Y++ Y
Sbjct: 899 NKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLY 958
Query: 1565 QLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWG 1609
+ +N L + PA T++ + L P+ +Y +VRA + +G G
Sbjct: 959 RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPG 1003
Score = 61.2 bits (147), Expect = 9e-09
Identities = 69/242 (28%), Positives = 98/242 (40%), Gaps = 26/242 (10%)
Query: 1511 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1570
STL + + +P P V + TS+ ++W E P+ Y ++++ N
Sbjct: 306 STLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPE-PVSYYIIQHKPKNSE 364
Query: 1571 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1630
EL++ I A T V L P Y FRV A + G G E V+T S+ P S
Sbjct: 365 ELYK-EIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSS---- 419
Query: 1631 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPAT 1688
AP + LS ++ + W+ P PNG I GY V T + Q
Sbjct: 420 ------------APRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWM 467
Query: 1689 AFRVDGDSPESRLTVPG-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGS 1747
V +S++T G L Y KV A T+ G GP I I +Q G P L
Sbjct: 468 KHNV----ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVI-TQTGVPGQPLNF 522
Query: 1748 RA 1749
+A
Sbjct: 523 KA 524
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 19/229 (8%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 397 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 456
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 457 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 514
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 567
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 568 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP 613
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 914 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 973
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 974 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1033
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1034 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1082
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1083 FVLTNRGNSAGG 1094
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 102 bits (253), Expect = 4e-21
Identities = 151/681 (22%), Positives = 250/681 (36%), Gaps = 93/681 (13%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPS-VELTNLYP 1188
P P + + I W + +P+ Y + +SE +D + + L P
Sbjct: 313 PGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSP 372
Query: 1189 YCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFNVVSSTVTQLSWAEPAETN 1247
Y DYE +V A G GP S V +T ++ PS P + ++SST + W EP E N
Sbjct: 373 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 432
Query: 1248 GEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWG 1307
G+I Y V Y + D + + K V + +++ I NL + Y V A G G
Sbjct: 433 GQIQGYRVYYTM--DPTQHVNNWMKHNVAD--SQITTIGNLVPQKTYSVKVLAFTSIGDG 488
Query: 1308 PEREAIINLATQ---PKRPMSIPIIPD--IPIVDAQSGEDYDSFLMYSDDVLRSPSGSQR 1362
P + I + TQ P +P++ P+ I+ + + D+ Y + V + +
Sbjct: 489 P-LSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANY-ELVYKDGEHGEE 546
Query: 1363 PSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGA 1422
++ + G ++ + L L R+ R P L + S R+ ++ P PP D
Sbjct: 547 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK-PSAPPQDISC 605
Query: 1423 GGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVL 1482
+ + PP E N + +T S PH +L
Sbjct: 606 TSPSSTSILVSWQPPPVE-------------KQNGI--ITEYSIKYTAVDGEDDKPHEIL 650
Query: 1483 STSSTLTR----------DYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT 1532
S T+ +Y +T + H+ P S L R VP P
Sbjct: 651 GIPSDTTKYLLEQLEKWTEYR-ITVTAHTDVGPGPESLSVLI-------RTNEDVPSGPP 702
Query: 1533 RLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH-------------RL 1575
R V A+ TS++VSW+ P + ++GY V Y + GE +
Sbjct: 703 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQW 762
Query: 1576 NIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSA 1635
+ + +++ L P SY V A + +G G + + + P P
Sbjct: 763 EFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR------- 815
Query: 1636 FTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGD 1695
LV ++ + W P G + GY + + P T ++
Sbjct: 816 -----------LVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGR-KDMEPLTT--LEFS 861
Query: 1696 SPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGL---- 1751
E T + + Y F++ AR GFG E I+I + FPQ G
Sbjct: 862 EKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTS 921
Query: 1752 ----FQHPLQSEYSSITTTHT 1768
+Q P+ +E + I T +T
Sbjct: 922 VQLSWQPPVLAERNGIITKYT 942
Score = 74.7 bits (182), Expect = 8e-13
Identities = 121/525 (23%), Positives = 198/525 (37%), Gaps = 81/525 (15%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
G P N A+ I +W PP + + G+ E + S L L
Sbjct: 504 GQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLK 563
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSWAEPA-- 1244
P Y ++ A QG G ++ +S RT Q PS P + ++ SST +SW P
Sbjct: 564 PNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVE 623
Query: 1245 ETNGEITAYEVCYGLVN-DDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNG 1303
+ NG IT Y + Y V+ +D++P ++L L+E L + YR TV A
Sbjct: 624 KQNGIITEYSIKYTAVDGEDDKP----HEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 679
Query: 1304 AGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQS----------GEDYDSFLMYSDDV 1353
G GPE +++ + T P P ++ V++ S + + Y
Sbjct: 680 VGPGPESLSVL-IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHY 738
Query: 1354 LRSPSGSQR--PSVSDD--TGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSD 1409
+R +G + P + D W+F+ ++ + L PE L+ ++ +
Sbjct: 739 VRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDM----IISGLQPETSYSLTVTAYTTKG 794
Query: 1410 AEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAY 1469
A P G A PG P + + +M+ A H T
Sbjct: 795 DGARSKPKLVSTTG---------AVPGKPRLVINHTQMNTALI----QWHPPVDTFGPLQ 841
Query: 1470 GTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSV---SSHDSRLTA- 1525
G L +D LT E S D+ T T + +S+ RL+A
Sbjct: 842 GYRLKFG------------RKDMEPLTTLEFSEK----EDHFTATDIHKGASYVFRLSAR 885
Query: 1526 -------------GVPDT-----PTRLVFSALGPTSLRVSWQEP-RCERP--LQGYSVEY 1564
+P+ P L TS+++SWQ P ER + Y++ Y
Sbjct: 886 NKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLY 945
Query: 1565 QLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWG 1609
+ +N L + PA T++ + L P+ +Y +VRA + +G G
Sbjct: 946 RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPG 990
Score = 61.2 bits (147), Expect = 9e-09
Identities = 69/242 (28%), Positives = 98/242 (40%), Gaps = 26/242 (10%)
Query: 1511 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1570
STL + + +P P V + TS+ ++W E P+ Y ++++ N
Sbjct: 293 STLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPE-PVSYYIIQHKPKNSE 351
Query: 1571 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1630
EL++ I A T V L P Y FRV A + G G E V+T S+ P S
Sbjct: 352 ELYK-EIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSS---- 406
Query: 1631 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPAT 1688
AP + LS ++ + W+ P PNG I GY V T + Q
Sbjct: 407 ------------APRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWM 454
Query: 1689 AFRVDGDSPESRLTVPG-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGS 1747
V +S++T G L Y KV A T+ G GP I I +Q G P L
Sbjct: 455 KHNV----ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVI-TQTGVPGQPLNF 509
Query: 1748 RA 1749
+A
Sbjct: 510 KA 511
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 19/229 (8%)
Query: 1106 DELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKYW 1162
+ + R S+ + +Q AP++ A+ S I W P +G+ GYRV Y
Sbjct: 384 NNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYT 443
Query: 1163 IQGDSE----SEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
+ + ++ DS++ ++ NL P Y +KV A+ + G+GP SS + T
Sbjct: 444 MDPTQHVNNWMKHNVADSQITTIG--NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTG 501
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP +P S T LSW P + I YE+ Y + G +++ ++
Sbjct: 502 VPGQPLNFKAEPESETSILLSWTPP--RSDTIANYELVY-----KDGEHGEEQRITIEPG 554
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIP 1327
+ L + L+ + Y + + AR+ G G A I+ T +P + P
Sbjct: 555 TSYRL--QGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSKPSAPP 600
Score = 47.8 bits (112), Expect = 1e-04
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 17/192 (8%)
Query: 1122 PPHGDLGAPQNPNAKAAGSRKIHFNWLPPS-GKPMGYRVKYWIQGDSES-----EAHLLD 1175
P G PQN +++ S + +W PP + G KY + + L+
Sbjct: 901 PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIV 960
Query: 1176 SKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTV 1235
++ LT L P Y++KV A+ ++G GPYS V RT V T
Sbjct: 961 PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTS 1020
Query: 1236 TQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYR 1295
LSW P N + + ++ DD + + VD + L++ NL+ + Y
Sbjct: 1021 VLLSWEIPENYNSAMP-----FKILYDDGKMVEE-----VDGRATQKLIV-NLKPEKSYS 1069
Query: 1296 YTVKARNGAGWG 1307
+ + R + G
Sbjct: 1070 FVLTNRGNSAGG 1081
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 99.0 bits (245), Expect = 4e-20
Identities = 150/648 (23%), Positives = 242/648 (37%), Gaps = 68/648 (10%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLL-DSKVPSVELTNLY 1187
AP P + I W + P+ Y V + + + D + L
Sbjct: 334 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 393
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAET 1246
P +YE+ V A + G+GP S V RT ++ P S P + ++S+T + W EP E
Sbjct: 394 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 453
Query: 1247 NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
NG I Y V Y + + P+G +K VD+ + + + +L E + Y V A G
Sbjct: 454 NGLIRGYRVYYTM--EPEHPVGNWQKHNVDD--SLLTTVGSLLEDETYTVRVLAFTSVGD 509
Query: 1307 GPEREAIINLATQ---PKRPMSI--PIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQ 1361
GP + I + TQ P +PM++ + I + S +S + Y + + R +
Sbjct: 510 GPLSDP-IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKY-ELLFREGDHGR 567
Query: 1362 RPSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGG 1421
+ D + E L R+ R P L R+ ++ P D
Sbjct: 568 EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKC 627
Query: 1422 AGGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRV 1481
+ ++ S P PP H NG A G + + + + P ++
Sbjct: 628 VSVRSTAILVSWRPPPPETH--NG----ALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQI 681
Query: 1482 LSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLV-FSALG 1540
L + Y T +H+ P S+ V R VP P R V AL
Sbjct: 682 LLEALEKWTQYRITT---VAHTEVGPGPESSPVVV-----RTDEDVPSAPPRKVEAEALN 733
Query: 1541 PTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELH-------------RLNIPNPAQTS 1584
T++RV W+ P R ++GY V Y + G E + + A+
Sbjct: 734 ATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYE 793
Query: 1585 VVVEDLLPNHSYVFRVRAQSQEGWG-REREGVITIESQVHPQSPLCPLPGSAFTLSTPSA 1643
+V+ +L P +Y V A + +G G R + V+ + V + TLS
Sbjct: 794 MVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP----------TLSVQQT 843
Query: 1644 PGPLVFTALSPDSLQLSWERPRRPNGD-IVGYLVTCEMAQGGGPATAFRVDGDSPESRLT 1702
P SL WE P D ++GY + AT ++ E R T
Sbjct: 844 P---------EGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLAT---LEFPPSEDRYT 891
Query: 1703 VPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAG 1750
G+ + Y F++ AR+ G G E +++I PQ+ AG
Sbjct: 892 ASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAG 939
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/194 (30%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWI---QGDSESEAHLLDSKVPSVELT 1184
G P N A+A I +W PP + + +KY + +GD E S +
Sbjct: 526 GQPMNLRAEARSETSITLSWSPPRQESI---IKYELLFREGDHGREVGRTFDPTTSYVVE 582
Query: 1185 NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAEP 1243
+L P +Y ++ A QG G ++ +V RT Q PS P + V V ST +SW P
Sbjct: 583 DLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPP 642
Query: 1244 A-ET-NGEITAYEVCYG-LVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
ET NG + Y V Y L ++D P K+V P +L+E L + YR T A
Sbjct: 643 PPETHNGALVGYSVRYRPLGSEDPEP----KEVNGIPPTTTQILLEALEKWTQYRITTVA 698
Query: 1301 RNGAGWGPEREAII 1314
G GPE ++
Sbjct: 699 HTEVGPGPESSPVV 712
Score = 53.9 bits (128), Expect = 1e-06
Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1527 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1586
+P P + + TS+ ++W + P+ Y +EY+ + +++ + T
Sbjct: 331 LPKAPGTPMVTENTATSITITWDSGNPD-PVSYYVIEYKSKSQDGPYQIK-EDITTTRYS 388
Query: 1587 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1646
+ L PN Y V A + G G E V+T + P S AP
Sbjct: 389 IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPAS----------------APRN 432
Query: 1647 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1704
+ LS ++ + WE P PNG I GY V T E G VD +S LT
Sbjct: 433 VQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD----DSLLTTV 488
Query: 1705 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1749
G L E+ Y +V A T+ G GP + I +++Q G P + RA
Sbjct: 489 GSLLEDETYTVRVLAFTSVGDGPLSDP-IQVKTQQGVPGQPMNLRA 533
Score = 43.5 bits (101), Expect = 0.002
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 1639 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGY-LVTCEMAQGGGPATAFRVDGDSP 1697
S P APG + T + S+ ++W+ N D V Y ++ + GP +++ D
Sbjct: 330 SLPKAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEYKSKSQDGP---YQIKEDIT 383
Query: 1698 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1757
+R ++ GLS N Y+ V A + G GP E ++T + G P R +Q
Sbjct: 384 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVT---RTGEQAPASAPR------NVQ 434
Query: 1758 SEYSSITTTHTSATEPFLVDGLTLG 1782
+ S TT EP +GL G
Sbjct: 435 ARMLSATTMIVQWEEPVEPNGLIRG 459
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/186 (25%), Positives = 68/186 (36%), Gaps = 15/186 (8%)
Query: 1089 GAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWL 1148
G H G + + R L + + P G + +AG+ + WL
Sbjct: 894 GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGT--VLLRWL 951
Query: 1149 PP-SGKPMGYRVKYWIQGDSES------EAHLLDSKVPSVE----LTNLYPYCDYEMKVC 1197
PP + G VKY + E L + P E L L P Y+++V
Sbjct: 952 PPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVR 1011
Query: 1198 AYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCY 1257
A+ +G GP+S V RT P ++ T LSW P N T Y++ Y
Sbjct: 1012 AHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSP-TPYKIQY 1070
Query: 1258 -GLVND 1262
GL D
Sbjct: 1071 NGLTLD 1076
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 98.2 bits (243), Expect = 6e-20
Identities = 149/639 (23%), Positives = 240/639 (37%), Gaps = 59/639 (9%)
Query: 1129 APQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLL-DSKVPSVELTNLY 1187
AP P + I W + P+ Y V + + + D + L
Sbjct: 321 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 380
Query: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVP-SEPGRLAFNVVSSTVTQLSWAEPAET 1246
P +YE+ V A + G+GP S V RT ++ P S P + ++S+T + W EP E
Sbjct: 381 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 440
Query: 1247 NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
NG I Y V Y + + P+G +K VD+ + + + +L E + Y V A G
Sbjct: 441 NGLIRGYRVYYTM--EPEHPVGNWQKHNVDD--SLLTTVGSLLEDETYTVRVLAFTSVGD 496
Query: 1307 GPEREAIINLATQ---PKRPMSI--PIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQ 1361
GP + I + TQ P +PM++ + I + S +S + Y + + R +
Sbjct: 497 GPLSDP-IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKY-ELLFREGDHGR 554
Query: 1362 RPSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGG 1421
+ D + E L R+ R P L R+ ++ P D
Sbjct: 555 EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKC 614
Query: 1422 AGGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRV 1481
+ ++ S P PP H NG A G + + + + P ++
Sbjct: 615 VSVRSTAILVSWRPPPPETH--NG----ALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQI 668
Query: 1482 LSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPTRLV-FSALG 1540
L + Y T +H+ P S+ V R VP P R V AL
Sbjct: 669 LLEALEKWTQYRITT---VAHTEVGPGPESSPVVV-----RTDEDVPSAPPRKVEAEALN 720
Query: 1541 PTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELHR----LNIPNPAQTSVVVEDLLPN 1593
T++RV W+ P R ++GY V Y + G E ++ +V+ +L P
Sbjct: 721 ATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPE 780
Query: 1594 HSYVFRVRAQSQEGWG-REREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTAL 1652
+Y V A + +G G R + V+ + V + TLS P
Sbjct: 781 TAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP----------TLSVQQTP-------- 822
Query: 1653 SPDSLQLSWERPRRPNGD-IVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVP 1711
SL WE P D ++GY + AT ++ E R T G+ +
Sbjct: 823 -EGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLAT---LEFPPSEDRYTASGVHKGAT 878
Query: 1712 YKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAG 1750
Y F++ AR+ G G E +++I PQ+ AG
Sbjct: 879 YVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAG 917
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/194 (30%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWI---QGDSESEAHLLDSKVPSVELT 1184
G P N A+A I +W PP + + +KY + +GD E S +
Sbjct: 513 GQPMNLRAEARSETSITLSWSPPRQESI---IKYELLFREGDHGREVGRTFDPTTSYVVE 569
Query: 1185 NLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAEP 1243
+L P +Y ++ A QG G ++ +V RT Q PS P + V V ST +SW P
Sbjct: 570 DLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPP 629
Query: 1244 A-ET-NGEITAYEVCYG-LVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
ET NG + Y V Y L ++D P K+V P +L+E L + YR T A
Sbjct: 630 PPETHNGALVGYSVRYRPLGSEDPEP----KEVNGIPPTTTQILLEALEKWTQYRITTVA 685
Query: 1301 RNGAGWGPEREAII 1314
G GPE ++
Sbjct: 686 HTEVGPGPESSPVV 699
Score = 53.9 bits (128), Expect = 1e-06
Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 26/226 (11%)
Query: 1527 VPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVV 1586
+P P + + TS+ ++W + P+ Y +EY+ + +++ + T
Sbjct: 318 LPKAPGTPMVTENTATSITITWDSGNPD-PVSYYVIEYKSKSQDGPYQIK-EDITTTRYS 375
Query: 1587 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1646
+ L PN Y V A + G G E V+T + P S AP
Sbjct: 376 IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPAS----------------APRN 419
Query: 1647 LVFTALSPDSLQLSWERPRRPNGDIVGYLV--TCEMAQGGGPATAFRVDGDSPESRLTVP 1704
+ LS ++ + WE P PNG I GY V T E G VD +S LT
Sbjct: 420 VQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD----DSLLTTV 475
Query: 1705 G-LSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRA 1749
G L E+ Y +V A T+ G GP + I +++Q G P + RA
Sbjct: 476 GSLLEDETYTVRVLAFTSVGDGPLSDP-IQVKTQQGVPGQPMNLRA 520
Score = 43.5 bits (101), Expect = 0.002
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 1639 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGY-LVTCEMAQGGGPATAFRVDGDSP 1697
S P APG + T + S+ ++W+ N D V Y ++ + GP +++ D
Sbjct: 317 SLPKAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEYKSKSQDGP---YQIKEDIT 370
Query: 1698 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ 1757
+R ++ GLS N Y+ V A + G GP E ++T + G P R +Q
Sbjct: 371 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVT---RTGEQAPASAPR------NVQ 421
Query: 1758 SEYSSITTTHTSATEPFLVDGLTLG 1782
+ S TT EP +GL G
Sbjct: 422 ARMLSATTMIVQWEEPVEPNGLIRG 446
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/186 (25%), Positives = 68/186 (36%), Gaps = 15/186 (8%)
Query: 1089 GAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWL 1148
G H G + + R L + + P G + +AG+ + WL
Sbjct: 872 GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGT--VLLRWL 929
Query: 1149 PP-SGKPMGYRVKYWIQGDSES------EAHLLDSKVPSVE----LTNLYPYCDYEMKVC 1197
PP + G VKY + E L + P E L L P Y+++V
Sbjct: 930 PPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVR 989
Query: 1198 AYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCY 1257
A+ +G GP+S V RT P ++ T LSW P N T Y++ Y
Sbjct: 990 AHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSP-TPYKIQY 1048
Query: 1258 -GLVND 1262
GL D
Sbjct: 1049 NGLTLD 1054
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 97.1 bits (240), Expect = 1e-19
Identities = 72/209 (34%), Positives = 87/209 (41%), Gaps = 54/209 (25%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C G V G+CVC G++G+ C+ T C R+ C GRG C+ G C+C
Sbjct: 346 CGEGGRCVDGRCVCWPGYTGEDCSTRT--------CPRD-----CRGRGRCEDGECIC-- 390
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCD---CP-------- 576
+ Y G C + CP CN RGRC G+CVC PG+TG C CP
Sbjct: 391 DTGYSGDDCGVRS--CPGD----CNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGR 444
Query: 577 LSNATCIDSNG------------GICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPG 624
N C+ + G G C GRG CE GRC C YT C + PG
Sbjct: 445 CENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPG--YTGRDCG---TRACPG 499
Query: 625 LCEDLRSCVQ----CQAWGTGEKKG-RTC 648
C CV C TGE G R C
Sbjct: 500 DCRGRGRCVDGRCVCNPGFTGEDCGSRRC 528
Score = 89.4 bits (220), Expect = 3e-17
Identities = 69/200 (34%), Positives = 89/200 (44%), Gaps = 44/200 (22%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C+ G V G+CVC G++G +C + C + C GRG C G CVC
Sbjct: 191 CNDQGRCVRGRCVCFPGYTGPSCGWPS--------CPGD-----CQGRGRCVQGVCVC-- 235
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584
+ G C + CPR C+ RGRC G+CVC+PG+TG C CP
Sbjct: 236 RAGFSGPDCSQRS--CPRG----CSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG------ 283
Query: 585 SNGGICNGRGHCECGRCHCHQQSLYTDTICEIN---YSAIHPGLCEDLRSCVQCQAWGTG 641
C+ RG CE GRC C+ YT C + G C+D R CV C TG
Sbjct: 284 -----CSQRGRCENGRCVCNPG--YTGEDCGVRSCPRGCSQRGRCKDGR-CV-CDPGYTG 334
Query: 642 EKKG-RTCE-ECNFKVKMVD 659
E G R+C +C + VD
Sbjct: 335 EDCGTRSCPWDCGEGGRCVD 354
Score = 89.4 bits (220), Expect = 3e-17
Identities = 56/164 (34%), Positives = 75/164 (45%), Gaps = 31/164 (18%)
Query: 443 GLKMDAGIICDVCTCELQKEVRSAR--CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDI 500
GL D +CD RS C G + G+CVC +G+SG+ C +
Sbjct: 536 GLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCG--------V 587
Query: 501 QPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG 560
+ C + CS G CQ G C+C+ EG Y + C CP C+ RGRC G
Sbjct: 588 RQCPND-----CSQHGVCQDGVCICW-EG-YVSEDCSIRT--CPSN----CHGRGRCEEG 634
Query: 561 QCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCH 604
+C+C+PG+TGP+C + A C GRG C G C CH
Sbjct: 635 RCLCDPGYTGPTCATRMCPAD--------CRGRGRCVQGVCLCH 670
Score = 87.4 bits (215), Expect = 1e-16
Identities = 70/200 (35%), Positives = 87/200 (43%), Gaps = 35/200 (17%)
Query: 460 QKEVRSARCSFNGDFVCGQCVCS--EGWSGQTCNCST-GSLSDIQPCLREGE-DKPCSGR 515
Q +VR+ CS +G F +C CS GW G TC+ T + P G C+ +
Sbjct: 136 QTDVRTL-CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQ 194
Query: 516 GECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC-- 573
G C G CVC+ Y G C + + CP C RGRC G CVC G++GP C
Sbjct: 195 GRCVRGRCVCF--PGYTGPSCGWPS--CPGD----CQGRGRCVQGVCVCRAGFSGPDCSQ 246
Query: 574 -DCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEIN---YSAIHPGLCEDL 629
CP C+ RG CE GRC C YT C + G CE+
Sbjct: 247 RSCPRG-----------CSQRGRCEGGRCVCDPG--YTGDDCGMRSCPRGCSQRGRCENG 293
Query: 630 RSCVQCQAWGTGEKKG-RTC 648
R CV C TGE G R+C
Sbjct: 294 R-CV-CNPGYTGEDCGVRSC 311
Score = 71.2 bits (173), Expect = 8e-12
Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 35/184 (19%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C G G+C+C G++G+ C + C + C GRG C G CVC
Sbjct: 470 CRGRGRCESGRCMCWPGYTGRDCGT--------RACPGD-----CRGRGRCVDGRCVC-- 514
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
+ G+ C + +CP C G C G CVC+ G++G C S +C
Sbjct: 515 NPGFTGEDC--GSRRCPGD----CRGHGLCEDGVCVCDAGYSGEDC----STRSC----P 560
Query: 588 GICNGRGHCECGRCHCHQQSLYTDTICEINY---SAIHPGLCEDLRSCVQCQAWGTGEKK 644
G C GRG C GRC C + Y+ C + G+C+D C+ + + + +
Sbjct: 561 GGCRGRGQCLDGRCVC--EDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVSEDCS 617
Query: 645 GRTC 648
RTC
Sbjct: 618 IRTC 621
Score = 70.9 bits (172), Expect = 1e-11
Identities = 47/152 (30%), Positives = 61/152 (40%), Gaps = 31/152 (20%)
Query: 452 CDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKP 511
C + TC + C G G+C+C G++G TC + C +
Sbjct: 616 CSIRTCP-------SNCHGRGRCEEGRCLCDPGYTGPTCAT--------RMCPAD----- 655
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C GRG C G C+C+ Y G+ C + G C R C GQCVC G+ GP
Sbjct: 656 CRGRGRCVQGVCLCHVG--YGGEDCGQEEPPASACPGG-CGPRELCRAGQCVCVEGFRGP 712
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603
C I + G C GRG C G C C
Sbjct: 713 DC--------AIQTCPGDCRGRGECHDGSCVC 736
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 32/116 (27%)
Query: 466 ARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKP--------CSGRGE 517
A C G V G C+C G+ G+ C G+++P C R
Sbjct: 654 ADCRGRGRCVQGVCLCHVGYGGEDC----------------GQEEPPASACPGGCGPREL 697
Query: 518 CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC 573
C+ G CVC EG + G C CP C RG C G CVC+ G+ G C
Sbjct: 698 CRAGQCVCV-EG-FRGPDCAIQT--CPGD----CRGRGECHDGSCVCKDGYAGEDC 745
Score = 53.5 bits (127), Expect = 2e-06
Identities = 55/206 (26%), Positives = 83/206 (40%), Gaps = 25/206 (12%)
Query: 1515 SVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHR 1574
S S + L +P L + +SLR+SW + P + V+Y+ +G
Sbjct: 3434 SADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV--AQGPFDSFVVQYRDTDG---QP 3488
Query: 1575 LNIPNPA-QTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPG 1633
+P A Q +V VEDL P Y F + G +R G ++ P+ P
Sbjct: 3489 RAVPVAADQRTVTVEDLEPGKKYKFLLYGLL----GGKRLGPVSALGMTAPEEDT---PA 3541
Query: 1634 SAFTLSTPSAP-----GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPAT 1688
P P G L T +PDS++LSW + P V + G
Sbjct: 3542 PELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFV-----VQYEDTNGQPQ 3596
Query: 1689 AFRVDGDSPESRLTVPGLSENVPYKF 1714
A VDGD +S++ + GL + PY+F
Sbjct: 3597 ALLVDGD--QSKILISGLEPSTPYRF 3620
Score = 48.9 bits (115), Expect = 4e-05
Identities = 52/176 (29%), Positives = 73/176 (41%), Gaps = 20/176 (11%)
Query: 1541 PTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1599
P SL +SW P E + V+Y+ NG G+ + +P + V + L P+H Y
Sbjct: 3071 PDSLSLSWMVP--EGQFDHFLVQYR--NGDGQPKAVRVPGH-EDGVTISGLEPDHKYKMN 3125
Query: 1600 VRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDSL 1657
+ G +R G ++ ++P P S P P G L T SPDSL
Sbjct: 3126 LYGFH----GGQRVGPVSAIGVTEEETP-SPTEPSTEAPEAPEEPLLGELTVTGSSPDSL 3180
Query: 1658 QLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1713
LSW P+ G + T + G RV G+ ES +TV GL YK
Sbjct: 3181 SLSWTVPQ---GRFDSF--TVQYKDRDGQPQVVRVRGE--ESEVTVGGLEPGRKYK 3229
Score = 48.5 bits (114), Expect = 6e-05
Identities = 64/240 (26%), Positives = 93/240 (38%), Gaps = 30/240 (12%)
Query: 1534 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLP 1592
L + + P SLR+SW + P + V+Y+ G +P + V V L P
Sbjct: 1267 LTVTGVTPDSLRLSWTV--AQGPFDSFMVQYKDAQG---QPQAVPVAGDENEVTVPGLDP 1321
Query: 1593 NHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPG-SAFTLSTPSAP-----GP 1646
+ Y + GR+R G ++ ++ PQ + P + P +P G
Sbjct: 1322 DRKYKMNLYGLR----GRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGE 1377
Query: 1647 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1706
L T SPDSL L W P+ G + T + G A RV G ES +TV GL
Sbjct: 1378 LTVTGSSPDSLSLFWTVPQ---GSFDSF--TVQYKDRDGRPRAVRVGG--KESEVTVGGL 1430
Query: 1707 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTT 1766
YK + EG +R G + S G PQ + PL+ +T T
Sbjct: 1431 EPGHKYKMHLYG-LHEG---QRVGPV---SAVGVTAPQQEETPPATESPLEPRLGELTVT 1483
Score = 47.4 bits (111), Expect = 1e-04
Identities = 59/212 (27%), Positives = 85/212 (40%), Gaps = 31/212 (14%)
Query: 1516 VSSHDSRLTAGVPDTPTR---------LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQL 1566
V+ ++ T VP T L + P SL +SW P E + V+Y+
Sbjct: 2821 VTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVP--EGQFDHFLVQYR- 2877
Query: 1567 LNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI--ESQVH 1623
NG G+ + +P + V + L P+H Y + G +R G I++ +
Sbjct: 2878 -NGDGQPKVVRVPGH-EDGVTISGLEPDHKYKMNLYGFH----GGQRVGPISVIGVTAAE 2931
Query: 1624 PQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMA 1681
++P P S P P G L T SPDSL LSW P+ G + T +
Sbjct: 2932 EETP-APTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ---GRFDSF--TVQYK 2985
Query: 1682 QGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1713
G RV G+ ES +TV GL YK
Sbjct: 2986 DRDGRPQVVRVRGE--ESEVTVGGLEPGCKYK 3015
Score = 47.0 bits (110), Expect = 2e-04
Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 31/212 (14%)
Query: 1516 VSSHDSRLTAGVPD-TPTRLVFSALG--------PTSLRVSWQEPRCERPLQGYSVEYQL 1566
V+ ++ T VP TP + LG P SL +SW P E + V+Y+
Sbjct: 2607 VTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVP--EGQFDHFLVQYR- 2663
Query: 1567 LNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITI--ESQVH 1623
NG G+ + +P + V + L P+H Y + G +R G I++ +
Sbjct: 2664 -NGDGQPKAVRVPGH-EDGVTISGLEPDHKYKMNLYGFH----GGQRVGPISVIGVTAAE 2717
Query: 1624 PQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMA 1681
++P P S P P G L T SPDSL LSW P+ G + T +
Sbjct: 2718 EETP-SPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ---GHFDSF--TVQYK 2771
Query: 1682 QGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1713
G RV G+ ES +TV GL YK
Sbjct: 2772 DRDGRPQVMRVRGE--ESEVTVGGLEPGRKYK 2801
Score = 45.4 bits (106), Expect = 5e-04
Identities = 63/241 (26%), Positives = 98/241 (40%), Gaps = 38/241 (15%)
Query: 1543 SLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRA 1602
SL + W P E + ++Y+ +G + + + P Q S V+ L P Y F +
Sbjct: 1077 SLLLRWTVPEGE--FDSFVIQYKDRDG-QPQVVPVEGP-QRSAVITSLDPGRKYKFVLYG 1132
Query: 1603 QSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWE 1662
G++R G + E+++ PQS P PG TP G L T +PDSL LSW
Sbjct: 1133 FV----GKKRHGPLVAEAKILPQSD--PSPG------TPPHLGNLWVTDPTPDSLHLSW- 1179
Query: 1663 RPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKV-QARTT 1721
P G ++V + G V+G PE V L + Y+F +
Sbjct: 1180 --TVPEGQFDTFMV--QYRDRDGRPQVVPVEG--PERSFVVSSLDPDHKYRFTLFGIANK 1233
Query: 1722 EGFGP-EREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYS-------SITTTHTSATEP 1773
+ +GP +G E ++ P P+ + PL E + S+ + T A P
Sbjct: 1234 KRYGPLTADGTTAPERKEEPPRPE------FLEQPLLGELTVTGVTPDSLRLSWTVAQGP 1287
Query: 1774 F 1774
F
Sbjct: 1288 F 1288
Score = 44.3 bits (103), Expect = 0.001
Identities = 52/181 (28%), Positives = 72/181 (39%), Gaps = 28/181 (15%)
Query: 1541 PTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1599
P SL +SW P E + V+Y+ NG G+ + +P + V + L P+H Y
Sbjct: 2000 PDSLSLSWTVP--EGQFDHFLVQYR--NGDGQPKAVRVPGHEE-GVTISGLEPDHKYKMN 2054
Query: 1600 VRAQSQEGWGREREGVITI-------ESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTAL 1652
+ G +R G +++ E P P P A G L T
Sbjct: 2055 LYGFH----GGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPA----EEPLLGELTVTGS 2106
Query: 1653 SPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPY 1712
SPDSL LSW P+ G + T + G RV G+ ES +TV GL Y
Sbjct: 2107 SPDSLSLSWTVPQ---GRFDSF--TVQYKDRDGRPQVVRVGGE--ESEVTVGGLEPGRKY 2159
Query: 1713 K 1713
K
Sbjct: 2160 K 2160
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/183 (27%), Positives = 74/183 (40%), Gaps = 29/183 (15%)
Query: 1543 SLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFRVR 1601
SL +SW P E + V+++ NG G+ + +P + V + L P+H Y +
Sbjct: 2209 SLSLSWTVP--EGQFDHFLVQFK--NGDGQPKAVRVPGH-EDGVTISGLEPDHKYKMNLY 2263
Query: 1602 AQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP--------LVFTALS 1653
G +R G ++ P P S + P P P L T +
Sbjct: 2264 GFH----GGQRVGPVSAVGLTAPGKDEEMAPAS----TEPPTPEPPIKPRLEELTVTDAT 2315
Query: 1654 PDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1713
PDSL LSW P G +LV + G G A RV G E R+T+ GL + YK
Sbjct: 2316 PDSLSLSW---TVPEGQFDHFLV--QYKNGDGQPKATRVPGH--EDRVTISGLEPDNKYK 2368
Query: 1714 FKV 1716
+
Sbjct: 2369 MNL 2371
Score = 43.1 bits (100), Expect = 0.002
Identities = 55/196 (28%), Positives = 78/196 (39%), Gaps = 27/196 (13%)
Query: 1528 PDTPT--RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1585
P+ P L + P SL +SW P+ ++V+Y+ +G ++ ++ V
Sbjct: 2409 PEEPLLGELTVTGSSPDSLSLSWTVPQGR--FDSFTVQYKDRDGRP--QVVRVGGEESEV 2464
Query: 1586 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1645
V L P Y + + GR R G ++ PQ + P T APG
Sbjct: 2465 TVGGLEPGRKYKMHLYGLHE---GR-RVGPVSTVGVTAPQEDVDETPSP--TEPGTEAPG 2518
Query: 1646 P--------LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP 1697
P L T SPDSL LSW P+ G + T + G A RV G
Sbjct: 2519 PPEEPLLGELTVTGSSPDSLSLSWTVPQ---GRFDSF--TVQYKDRDGRPQAVRVGGQ-- 2571
Query: 1698 ESRLTVPGLSENVPYK 1713
ES++TV GL YK
Sbjct: 2572 ESKVTVRGLEPGRKYK 2587
Score = 42.0 bits (97), Expect = 0.005
Identities = 38/147 (25%), Positives = 58/147 (39%), Gaps = 24/147 (16%)
Query: 1521 SRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNP 1580
+R + V ++P L FS + TS +V+W P + V YQL +GGE + +
Sbjct: 3747 ARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRA--DSFKVSYQLADGGEPQSVQVDGQ 3804
Query: 1581 AQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLST 1640
A+T ++ L+P Y V S G+ PL G F +
Sbjct: 3805 ARTQ-KLQGLIPGARY--EVTVVSVRGFEESE-----------------PLTG--FLTTV 3842
Query: 1641 PSAPGPLVFTALSPDSLQLSWERPRRP 1667
P P L L+ L W+ P+ P
Sbjct: 3843 PDGPTQLRALNLTEGFAVLHWKPPQNP 3869
Score = 41.6 bits (96), Expect = 0.007
Identities = 135/648 (20%), Positives = 223/648 (34%), Gaps = 114/648 (17%)
Query: 1118 SSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSK 1177
SS PP G+L S + W P G+ + ++Y + D + + ++
Sbjct: 1059 SSGPPRLGELTVTDRT------SDSLLLRWTVPEGEFDSFVIQYKDR-DGQPQVVPVEGP 1111
Query: 1178 VPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVS-------CRTHQEVPSEPGRLAFNV 1230
S +T+L P Y K YG G+ + LV+ P G L
Sbjct: 1112 QRSAVITSLDPGRKY--KFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTD 1169
Query: 1231 VSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRE 1290
+ LSW P G+ + V Y + D RP + V V+ P+ R ++ +L
Sbjct: 1170 PTPDSLHLSWTVP---EGQFDTFMVQYR--DRDGRP----QVVPVEGPE-RSFVVSSLDP 1219
Query: 1291 SQPYRYTVKA-RNGAGWGP---EREAIINLATQPKRP--MSIPIIPDIPIVDAQSGE--- 1341
YR+T+ N +GP + +P RP + P++ ++ +
Sbjct: 1220 DHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRL 1279
Query: 1342 -------DYDSFLMYSDDVLRSP-----SGSQR----PSVSDDTGCGWKFEPLLGEELDL 1385
+DSF++ D P +G + P + D L G +
Sbjct: 1280 SWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQ--- 1336
Query: 1386 RRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNG 1445
R+ PE + A + D + P + G P S GE V G
Sbjct: 1337 -----RVGPESVV---AKTAPQEDVDETPSPTE------LGTEAPESPEEPLLGELTVTG 1382
Query: 1446 RMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPH-------RVLSTSSTLT-------RD 1491
S +SL T ++ + + RV S +T
Sbjct: 1383 -------SSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHK 1435
Query: 1492 YNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDTPT--RLVFSALGPTSLRVSWQ 1549
Y H P +T+ ++ P P L + + P S+ +SW
Sbjct: 1436 YKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWT 1495
Query: 1550 EPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLPNHSYVFRVRAQSQEGW 1608
P E + V+Y+ +G +P A Q V V +L P Y +
Sbjct: 1496 VP--EGQFDSFIVQYKDKDG---QPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDG-- 1548
Query: 1609 GREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDSLQLSWERPRR 1666
+R G +++ V +PL P P + + P P G L T ++PDS+ LSW
Sbjct: 1549 --QRMGPLSV---VIVTAPLPPAPATEAS-KPPLEPRLGELTVTDITPDSVGLSW---TV 1599
Query: 1667 PNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKF 1714
P G+ ++V + G D + +T+P L + YKF
Sbjct: 1600 PEGEFDSFVVQYKDRDGQPQVVPVAAD----QREVTIPDLEPSRKYKF 1643
Score = 40.8 bits (94), Expect = 0.012
Identities = 56/225 (24%), Positives = 89/225 (39%), Gaps = 34/225 (15%)
Query: 1520 DSRLTAGVPDTPT----RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRL 1575
++ TA P P L +L +SW E + ++Y +G +L +
Sbjct: 1869 ETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGE--FDSFEIQYTDRDG-QLQMV 1925
Query: 1576 NIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSA 1635
I + + + L +H Y+ + S + G + +E+ P+ P +A
Sbjct: 1926 RIGGD-RNDITLSGLESDHRYLVTLYGFSDG----KHVGPVHVEALTVPEEEKPSEPPTA 1980
Query: 1636 FTLSTPSAP-----GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF 1690
TP P G L T +PDSL LSW P G +LV + G G A
Sbjct: 1981 ----TPEPPIKPRLGELTVTDATPDSLSLSW---TVPEGQFDHFLV--QYRNGDGQPKAV 2031
Query: 1691 RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGF-GPEREGIITI 1734
RV G E +T+ GL + YK + GF G +R G +++
Sbjct: 2032 RVPGH--EEGVTISGLEPDHKYKMNLY-----GFHGGQRMGPVSV 2069
Score = 40.4 bits (93), Expect = 0.016
Identities = 51/177 (28%), Positives = 71/177 (40%), Gaps = 20/177 (11%)
Query: 1541 PTSLRVSWQEPRCERPLQGYSVEYQLLNG-GELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1599
P SL +SW P E + V+Y+ NG G+ +P + V + L P++ Y
Sbjct: 2316 PDSLSLSWTVP--EGQFDHFLVQYK--NGDGQPKATRVPGH-EDRVTISGLEPDNKYKMN 2370
Query: 1600 VRAQSQEGWGREREGVIT-IESQVHPQSPLCPLPGSAFTLSTPSAP--GPLVFTALSPDS 1656
+ G +R G ++ I + P S P P G L T SPDS
Sbjct: 2371 LYGFH----GGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDS 2426
Query: 1657 LQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1713
L LSW P+ G + T + G RV G+ ES +TV GL YK
Sbjct: 2427 LSLSWTVPQ---GRFDSF--TVQYKDRDGRPQVVRVGGE--ESEVTVGGLEPGRKYK 2476
Score = 38.9 bits (89), Expect = 0.046
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 30/203 (14%)
Query: 1534 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPA-QTSVVVEDLLP 1592
L + + P S+ +SW P E + V+Y+ +G +P A Q V + DL P
Sbjct: 1583 LTVTDITPDSVGLSWTVPEGE--FDSFVVQYKDRDG---QPQVVPVAADQREVTIPDLEP 1637
Query: 1593 NHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTAL 1652
+ Y F + Q+G +R +++E++ + P P G L T
Sbjct: 1638 SRKYKFLLFG-IQDG---KRRSPVSVEAKTVARGDASP--------GAPPRLGELWVTDP 1685
Query: 1653 SPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPY 1712
+PDSL+LSW P G ++V + GP V + E +TV L Y
Sbjct: 1686 TPDSLRLSW---TVPEGQFDSFVV--QFKDKDGPQV---VPVEGHERSVTVTPLDAGRKY 1737
Query: 1713 KFKVQARTTEGFGPEREGIITIE 1735
+F + G +R G +T +
Sbjct: 1738 RFLLYGL----LGKKRHGPLTAD 1756
Score = 38.9 bits (89), Expect = 0.046
Identities = 52/196 (26%), Positives = 77/196 (39%), Gaps = 24/196 (12%)
Query: 1528 PDTPT--RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1585
P+ P L + P SL +SW P+ ++V+Y+ +G ++ ++ V
Sbjct: 2948 PEEPLLGELTVTGSSPDSLSLSWTIPQGR--FDSFTVQYKDRDGRP--QVVRVRGEESEV 3003
Query: 1586 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP- 1644
V L P Y + EG +R G ++ P+ A TP P
Sbjct: 3004 TVGGLEPGCKYKMHLYGL-HEG---QRVGPVSAVGVTAPKDEAETT--QAVPTMTPEPPI 3057
Query: 1645 ----GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESR 1700
G L T +PDSL LSW P G +LV + G G A RV G E
Sbjct: 3058 KPRLGELTVTDATPDSLSLSW---MVPEGQFDHFLV--QYRNGDGQPKAVRVPGH--EDG 3110
Query: 1701 LTVPGLSENVPYKFKV 1716
+T+ GL + YK +
Sbjct: 3111 VTISGLEPDHKYKMNL 3126
Score = 38.1 bits (87), Expect = 0.079
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 13/118 (11%)
Query: 1529 DTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVE 1588
D P L A+ PT+L + W P+ E + + V Y + G + RL +P P ++
Sbjct: 841 DGPQDLRVVAVTPTTLELGWLRPQAE--VDRFVVSY-VSAGNQRVRLEVP-PEADGTLLT 896
Query: 1589 DLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1646
DL+P YV V A ER ++ + V + PL G T P GP
Sbjct: 897 DLMPGVEYVVTVTA--------ERGRAVSYPASVRANTGSSPL-GLLGTTDEPPPSGP 945
Score = 36.2 bits (82), Expect = 0.30
Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Query: 1146 NWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY-GAQGE 1204
NW+PP + ++V Y + E ++ +D + + +L L P YE+ V + G +
Sbjct: 3773 NWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEES 3832
Query: 1205 GPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEP 1243
P + ++ VP P +L ++ L W P
Sbjct: 3833 EPLTGFLT-----TVPDGPTQLRALNLTEGFAVLHWKPP 3866
Score = 35.8 bits (81), Expect = 0.39
Identities = 46/187 (24%), Positives = 72/187 (38%), Gaps = 29/187 (15%)
Query: 1534 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPN 1593
L + P SL +SW P+ ++V+Y+ +G ++ ++ V V L P
Sbjct: 2101 LTVTGSSPDSLSLSWTVPQGR--FDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPG 2156
Query: 1594 HSYVFRVRAQSQEGWGREREGV----ITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVF 1649
Y + + GR V +T + P +PL L G +
Sbjct: 2157 RKYKMHLYGLHE---GRRVGPVSAVGVTAPEEESPDAPLAKL-----------RLGQMTV 2202
Query: 1650 TALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSEN 1709
++ DSL LSW P G +LV + G G A RV G E +T+ GL +
Sbjct: 2203 RDITSDSLSLSW---TVPEGQFDHFLV--QFKNGDGQPKAVRVPGH--EDGVTISGLEPD 2255
Query: 1710 VPYKFKV 1716
YK +
Sbjct: 2256 HKYKMNL 2262
Score = 35.8 bits (81), Expect = 0.39
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 1127 LGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNL 1186
L AP++ AK R W P +P GY + + G E LL + S +L L
Sbjct: 3931 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEI-LLPGGITSHQLLGL 3989
Query: 1187 YPYCDYEMKVCAYGAQ 1202
+P Y ++ A Q
Sbjct: 3990 FPSTSYNARLQAMWGQ 4005
Score = 33.5 bits (75), Expect = 1.9
Identities = 51/230 (22%), Positives = 79/230 (34%), Gaps = 47/230 (20%)
Query: 1539 LGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVE-DLLPNHSYV 1597
L T++R W P+ Y +++ G P+ S + L P Y
Sbjct: 760 LEETTVRTEWTP--APGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ 817
Query: 1598 FRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSL 1657
VRA WG LP S + P L A++P +L
Sbjct: 818 VTVRALRGTSWG---------------------LPASKTITTMIDGPQDLRVVAVTPTTL 856
Query: 1658 QLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLT--VPGL--------- 1706
+L W RP ++ ++V+ G V ++ + LT +PG+
Sbjct: 857 ELGW---LRPQAEVDRFVVS--YVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAE 911
Query: 1707 -SENVPYKFKVQARTTEGFGPEREGII--TIESQDGGPFPQLGSRAGLFQ 1753
V Y V+A T G G++ T E GP G++A L Q
Sbjct: 912 RGRAVSYPASVRANT----GSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQ 957
Score = 33.1 bits (74), Expect = 2.5
Identities = 62/227 (27%), Positives = 92/227 (40%), Gaps = 39/227 (17%)
Query: 1528 PDTPT--RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1585
P+ P L + P SL +SW P+ ++V+Y+ +G ++ ++ V
Sbjct: 3162 PEEPLLGELTVTGSSPDSLSLSWTVPQGR--FDSFTVQYKDRDGQP--QVVRVRGEESEV 3217
Query: 1586 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1645
V L P Y + EG +R G + S V +PL P P L G
Sbjct: 3218 TVGGLEPGRKYKMHLYGL-HEG---QRVGPV---STVGITAPL-PTP-----LPVEPRLG 3264
Query: 1646 PLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPG 1705
L A++ DS+ LSW + G +LV AQ G A V GD + V G
Sbjct: 3265 ELAVAAVTSDSVGLSWTVAQ---GPFDSFLVQYRDAQ--GQPQAVPVSGDL--RAVAVSG 3317
Query: 1706 LSENVPYKFKVQARTTEGFG---PEREGIITIESQ---DGGPFPQLG 1746
L YKF + FG +R G + +E++ D P P+LG
Sbjct: 3318 LDPARKYKFLL-------FGLQNGKRHGPVPVEARTAPDTKPSPRLG 3357
Score = 31.6 bits (70), Expect = 7.4
Identities = 46/193 (23%), Positives = 73/193 (37%), Gaps = 24/193 (12%)
Query: 1528 PDTPT--RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSV 1585
P+ P L + P SL + W P + ++V+Y+ +G R ++ V
Sbjct: 1370 PEEPLLGELTVTGSSPDSLSLFWTVP--QGSFDSFTVQYKDRDGRP--RAVRVGGKESEV 1425
Query: 1586 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP- 1644
V L P H Y + EG +R G ++ PQ P P + +P P
Sbjct: 1426 TVGGLEPGHKYKMHLYGL-HEG---QRVGPVSAVGVTAPQQEETP-PAT----ESPLEPR 1476
Query: 1645 -GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTV 1703
G L T ++P+S+ LSW P G ++V + G D + +TV
Sbjct: 1477 LGELTVTDVTPNSVGLSW---TVPEGQFDSFIVQYKDKDGQPQVVPVAAD----QREVTV 1529
Query: 1704 PGLSENVPYKFKV 1716
L YK +
Sbjct: 1530 YNLEPERKYKMNM 1542
Score = 31.2 bits (69), Expect = 9.6
Identities = 54/241 (22%), Positives = 94/241 (39%), Gaps = 32/241 (13%)
Query: 1534 LVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPN 1593
L +A+ S+ +SW + P + V+Y+ G + + + + +V V L P
Sbjct: 3266 LAVAAVTSDSVGLSWTV--AQGPFDSFLVQYRDAQG-QPQAVPVSGDLR-AVAVSGLDPA 3321
Query: 1594 HSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALS 1653
Y F + Q G +R G + +E++ P + P G L T +
Sbjct: 3322 RKYKFLLFGL-QNG---KRHGPVPVEARTAPDTKPSPRLGE------------LTVTDAT 3365
Query: 1654 PDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYK 1713
PDS+ LSW P G+ ++V + G + + +TV GL + Y+
Sbjct: 3366 PDSVGLSW---TVPEGEFDSFVVQYKDKDGRLQVVPVAAN----QREVTVQGLEPSRKYR 3418
Query: 1714 FKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEP 1773
F + + G +R G I+ +S +L G + SS+ + T A P
Sbjct: 3419 FLLYGLS----GRKRLGPISADSTTAPLEKELPPHLGELT-VAEETSSSLRLSWTVAQGP 3473
Query: 1774 F 1774
F
Sbjct: 3474 F 3474
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 94.7 bits (234), Expect = 7e-19
Identities = 163/673 (24%), Positives = 260/673 (38%), Gaps = 96/673 (14%)
Query: 1130 PQNPNAKAAGSRKIHFNWLPPS-----GKPMGYRVKYWIQGDSESEAHLLDSKVPSVE-- 1182
P N +A+A S I F W PS G GY++ W + + E E ++ ++ P+ +
Sbjct: 795 PGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAW-EPEQEEEVTMVTAR-PNFQDS 852
Query: 1183 -----LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQ 1237
++ L + +Y V + G+GP S+ RTH++VP G L+F+ + T +
Sbjct: 853 IHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLK 912
Query: 1238 LSWAEPAETNGEITAYEVCYGLVNDDN-RPIGPMKKVLVDNPKNRMLLIENLRESQPYRY 1296
+SW EP E NG +T Y + + N N R + V ++ + L Y
Sbjct: 913 VSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLE------YRVTGLTALTTYTI 966
Query: 1297 TVKARNGAGWGPEREAIINLATQPK---RPMSIPIIPDIP-IVDAQSGEDYDSFLMYSDD 1352
V A G G + I+ P+ P ++ I P V Q YD S
Sbjct: 967 EVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRW 1026
Query: 1353 VLRSPSGSQRPSVSDDTGCGWKFEPLLGEELDLRRV-----------TWRLPPELIPRLS 1401
++ + G G W L E D R + ++R+ I S
Sbjct: 1027 LVEAQVGVV------GEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS 1080
Query: 1402 ASSGRSSDAEAPHGPPDDGGAG-----GKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTN 1456
S S + PPD A SL P P E+ NG P S
Sbjct: 1081 PPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEY--NGN-----PESVG 1133
Query: 1457 SLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTS- 1515
+++ + + +G LS V RV RDY E + + ++ + S
Sbjct: 1134 --YKIKYSRSDGHGKTLSHVVQDRV-------ERDYTIEDLEEWTEYRVQVQAFNAIGSG 1184
Query: 1516 --VSSHDSRLTAGVPDT-PTRLVFSALGPTSLRVSWQE-PRCERP--LQGYSVEYQLLNG 1569
+ R VP + PT + A +S+ V W E P +R + GY V Y+ +
Sbjct: 1185 PWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDS 1244
Query: 1570 GELHRL-NIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPL 1628
R + + S + L Y +V A ++ G G S HP
Sbjct: 1245 DTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDG----------SPSHP---- 1290
Query: 1629 CPLPGSAFTL-STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPA 1687
P TL P P ++F + S++L W+ P PNG I+ Y +T + A
Sbjct: 1291 ---PILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRL--NTTTA 1345
Query: 1688 TAFRVDGDSPESR-LTVPGLSENVPYKFKVQARTTEGFGPEREG-IITIESQDGGPFPQL 1745
V+ +P +R T GL Y F++ A+T +G+G E ++T E +D PQ
Sbjct: 1346 NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR---PQP 1402
Query: 1746 GSRAGLFQHPLQS 1758
SR + Q +++
Sbjct: 1403 PSRPMVQQEDVRA 1415
Score = 88.2 bits (217), Expect = 7e-17
Identities = 66/233 (28%), Positives = 108/233 (46%), Gaps = 25/233 (10%)
Query: 1119 SQPPPHGDLG------APQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWI--QG 1165
S PP +G AP+N A + ++ W PP +G GY++ +W +G
Sbjct: 1610 SSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRG 1669
Query: 1166 DSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR 1225
+ L SV+L NL Y Y + V A+ A G+GP S+ +T Q PS P
Sbjct: 1670 NLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSS 1729
Query: 1226 LAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNR---M 1282
+ F+ +++T +SW P NG + Y + Y + P+ + K++ + K
Sbjct: 1730 VKFSELTTTSVNVSWEAPQFPNGILEGYRLVY----EPCSPVDGVSKIVTVDVKGNSPLW 1785
Query: 1283 LLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIV 1335
L +++L E YR+ ++A+ +GPE EA N+ T P P P +PI+
Sbjct: 1786 LKVKDLAEGVTYRFRIRAKTFT-YGPEIEA--NVTTGPGE--GAPGPPGVPII 1833
Score = 80.5 bits (197), Expect = 1e-14
Identities = 73/250 (29%), Positives = 112/250 (44%), Gaps = 34/250 (13%)
Query: 1531 PTRLVFSALGPTSLRVSWQEPRCERP---LQGYSVEYQLLNGGEL-HRLNIPNPAQTSVV 1586
P +V T L V+W+ P + +QGY + + G L R+ A+ SV
Sbjct: 1627 PRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVK 1686
Query: 1587 VEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGP 1646
+++L +Y+ V A + G G P+S P G + PSAP
Sbjct: 1687 LKNLTGYTAYMVSVAAFNAAGDG--------------PRST--PTQGQT-QQAAPSAPSS 1729
Query: 1647 LVFTALSPDSLQLSWERPRRPNGDIVGYLVT---CEMAQGGGPATAFRVDGDSPESRLTV 1703
+ F+ L+ S+ +SWE P+ PNG + GY + C G V G+SP L V
Sbjct: 1730 VKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSP-LWLKV 1788
Query: 1704 PGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSI 1763
L+E V Y+F+++A+T +GPE E +T +G P P G+ P+ YSS
Sbjct: 1789 KDLAEGVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGP-----PGV---PIIVRYSSA 1839
Query: 1764 TTTHTSATEP 1773
H S+ +P
Sbjct: 1840 IAIHWSSGDP 1849
Score = 73.6 bits (179), Expect = 2e-12
Identities = 160/658 (24%), Positives = 244/658 (37%), Gaps = 112/658 (17%)
Query: 1129 APQNPNA--KAAGSRKIHFNWLPP--SGKPMGYRVKYWIQGDSESEAHL------LDSKV 1178
AP++P A R I+ W P P+ ++Y ++ SE+ A +D K
Sbjct: 592 APEHPVATLSTVERRAINLTWTKPFDGNSPL---IRYILEM-SENNAPWTVLLASVDPKA 647
Query: 1179 PSVELTNLYPYCDYEMKVCAYGAQGEGPYS-SLVSCRTHQEVPSEPGRLAFNVVSSTVT- 1236
SV + L P Y+ ++CA G+G +S +E P+ P + NV++S T
Sbjct: 648 TSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQ---NVIASGRTN 704
Query: 1237 ---QLSWAEPAET--NGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRES 1291
+ W P E+ NG + Y + Y L P+G K + D N LL+E+L
Sbjct: 705 QSIMIQWQPPPESHQNGILKGYIIRYCLA---GLPVGYQFKNITDADVNN-LLLEDLIIW 760
Query: 1292 QPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSD 1351
Y V A N AG G + Q +P +P V A++ +
Sbjct: 761 TNYEIEVAAYNSAGLGVYSSKVTEWTLQ-----GVPTVPP-GNVHAEA---------TNS 805
Query: 1352 DVLRSPSGSQRPSVSDDTGCGWK---FEPLLGEELDLRRVTWRLPPELIPRLSASSGRSS 1408
+R + P + G+K +EP EE+ + VT R + + SG
Sbjct: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM--VTARPNFQDSIHVGFVSGLKK 863
Query: 1409 DAE-----APHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNGRMDFAF------PGSTNS 1457
E P DG PGP G + +D + PG N
Sbjct: 864 FTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNG 923
Query: 1458 LHRMTTTSAAAYG------THLSPHV--PHRV--LSTSSTLTRDYNSLTRSEHSHSTTLP 1507
+ S Y TH P+V +RV L+ +T T + ++T
Sbjct: 924 ILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ----- 978
Query: 1508 RDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEP-RCERPLQGYSVEYQL 1566
S S+ S + +P PT L S +GP S+ + ++ + + + VE Q+
Sbjct: 979 ------VSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQV 1032
Query: 1567 LNGGE------LHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIES 1620
GE +H+L+ P S+ V DL P Y FR+R + I
Sbjct: 1033 GVVGEGEEWLLIHQLS-NEPDARSMEVPDLNPFTCYSFRMRQ-------------VNIVG 1078
Query: 1621 QVHPQSPLCPLPGSAFTLSTP--SAPGPLVFTALSPDSLQLSW----ERPRRPNGDIVGY 1674
P P + TL P AP + S SL L W E N + VGY
Sbjct: 1079 TSPPSQPSRKIQ----TLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY 1134
Query: 1675 LVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGII 1732
+ + G G T V D E T+ L E Y+ +VQA G GP + ++
Sbjct: 1135 KIKYSRSDGHG-KTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVV 1191
Score = 67.4 bits (163), Expect = 1e-10
Identities = 160/719 (22%), Positives = 262/719 (36%), Gaps = 135/719 (18%)
Query: 1120 QPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP-----SGKP--MGYRVKYW-IQGDSESEA 1171
Q PP D+ AP N + + A + W+P +G P +GY++KY G ++ +
Sbjct: 1093 QAPP--DM-APANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLS 1149
Query: 1172 HLLDSKVP-SVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSE-PGRLAFN 1229
H++ +V + +L + +Y ++V A+ A G GP+S V RT + VPS P ++
Sbjct: 1150 HVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 1209
Query: 1230 VVSSTVTQLSWAE--PAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIEN 1287
+S+ + W+E A+ NG + Y+V Y + D +P + LV+ +R +
Sbjct: 1210 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQP----RFWLVEGNSSRSAQLTG 1265
Query: 1288 LRESQPYRYTVKARNGAGWG-PEREAII--NLATQPKRPMSIPIIPDIPIVD-------- 1336
L + Y V A G G P I+ L P PM I + P++
Sbjct: 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGI-LFPEVRTTSVRLIWQPP 1324
Query: 1337 -AQSGEDYDSFLMYSDDVLRSPSGSQR---PSVSDDTGCGWKFEPLLGEELDLR-RVTWR 1391
A +G + + + + + + PS T G K E + + + R W
Sbjct: 1325 AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG 1384
Query: 1392 LPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVN--GRMDF 1449
E + + R P +D + S+ S PG G V
Sbjct: 1385 EAAEALVVTTEKRDRPQPPSRPMVQQED----VRARSVLLSWEPGSDGLSPVRYYTIQTR 1440
Query: 1450 AFPGSTNSLHRMTTTSAAA--YGTHLSPHVPH--RVLSTSSTLTRDYNSLTRSEHSHSTT 1505
P +LH + + A+ L P + RV +T+ D SE S S T
Sbjct: 1441 ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATN-----DIGDSEFSEESESLT 1495
Query: 1506 ----LPRDYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEP---RCERPLQ 1558
P + T+ SV+ H + TS+ + WQ P + L
Sbjct: 1496 TLQAAPDEAPTILSVTPHTT--------------------TSVLIRWQPPAEDKINGILL 1535
Query: 1559 GYSVE-----YQLLNGGELHRLNIP-----------------NPAQTSVVVEDLLPNHSY 1596
G+ + Y+ L G L +N P P+ T +++L + Y
Sbjct: 1536 GFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRY 1595
Query: 1597 VFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT--LSTPSAPGPLVFTALSP 1654
R+ + G G P SP P F +AP +V +
Sbjct: 1596 EIRMSVYNAVGEG--------------PSSP----PQEVFVGEAVPTAAPRNVVVHGATA 1637
Query: 1655 DSLQLSWERP--RRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPY 1712
L ++WE P NGDI GY + AQ G + E+ + + L+ Y
Sbjct: 1638 TQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKT-LFLAENSVKLKNLTGYTAY 1696
Query: 1713 KFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTTHTSAT 1771
V A G GP R ++Q P P ++S +TTT + +
Sbjct: 1697 MVSVAAFNAAGDGP-RSTPTQGQTQQAAP-----------SAPSSVKFSELTTTSVNVS 1743
Score = 56.6 bits (135), Expect = 2e-07
Identities = 41/136 (30%), Positives = 66/136 (48%), Gaps = 12/136 (8%)
Query: 1117 LSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQG--DSES 1169
L +PP PQN A ++ I W PP +G GY ++Y + G
Sbjct: 685 LPEEPPT----APPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQ 740
Query: 1170 EAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAF 1228
++ D+ V ++ L +L + +YE++V AY + G G YSS V+ T Q VP+ PG +
Sbjct: 741 FKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHA 800
Query: 1229 NVVSSTVTQLSWAEPA 1244
+ST + +W P+
Sbjct: 801 EATNSTTIRFTWNAPS 816
Score = 47.4 bits (111), Expect = 1e-04
Identities = 50/221 (22%), Positives = 89/221 (40%), Gaps = 24/221 (10%)
Query: 1528 PDTPTRLVFSALGPTSLRVSWQEPRCERP-LQGYSVEYQLLNG----GELHRLNIPNPAQ 1582
P P+ + FS L TS+ VSW+ P+ L+GY + Y+ + ++ +++ +
Sbjct: 1724 PSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSP 1783
Query: 1583 TSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPS 1642
+ V+DL +Y FR+RA++ +G E E +T PG P
Sbjct: 1784 LWLKVKDLAEGVTYRFRIRAKTFT-YGPEIEANVTTG------------PGEG----APG 1826
Query: 1643 APGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFR-VDGDSPESRL 1701
PG + S ++ + W G I Y++ + G + + +
Sbjct: 1827 PPGVPIIVRYS-SAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTF 1885
Query: 1702 TVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPF 1742
++ L V Y F+V A GFG ++ +Q PF
Sbjct: 1886 SMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPF 1926
Score = 42.7 bits (99), Expect = 0.003
Identities = 71/293 (24%), Positives = 112/293 (38%), Gaps = 36/293 (12%)
Query: 1452 PGSTNSLHRMTTTSAAAYGTHLSPHVPHRVL-----STSSTLTRDYNSLTRSEHSH-STT 1505
P S+ + T S TH P V R + +T T + L R+ H S T
Sbjct: 501 PPQDQSVIKGTQASMVCGVTH-DPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQT 559
Query: 1506 LPRDYSTLT----SVSSHDSRLT----AGVPDTPTRLV--FSALGPTSLRVSWQEP-RCE 1554
D T T S +DSR +P P V S + ++ ++W +P
Sbjct: 560 WSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGN 619
Query: 1555 RPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREG 1614
PL Y +E N L +P TSV V+ L+P SY FR+ A + G G+ +
Sbjct: 620 SPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKD 679
Query: 1615 VITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERP--RRPNGDIV 1672
+ P P P P ++ + + S+ + W+ P NG +
Sbjct: 680 TERVSLPEEP--PTAP-------------PQNVIASGRTNQSIMIQWQPPPESHQNGILK 724
Query: 1673 GYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFG 1725
GY++ +A G F+ D+ + L + L Y+ +V A + G G
Sbjct: 725 GYIIRYCLA-GLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLG 776
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 567 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 615
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 616 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 665
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 666 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 716
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 717 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 767
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 589 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 641
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 642 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 690
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 691 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 736
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 737 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 794
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 795 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 536 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 587
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 588 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 638
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 639 CVKGECHCSTGWGGVNCE 656
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 566 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 614
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 615 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 664
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 665 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 715
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 716 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 766
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 588 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 640
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 641 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 689
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 690 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 735
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 736 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 793
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 794 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 839
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 535 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 586
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 587 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 637
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 638 CVKGECHCSTGWGGVNCE 655
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 91.3 bits (225), Expect = 8e-18
Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 41/234 (17%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527
C NG++ G CVC GW G C+ + C+ D C G G C G C+C
Sbjct: 567 CGGNGEYEKGHCVCRHGWKGPECDVPE------EQCI----DPTCFGHGTCIMGVCICV- 615
Query: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587
Y+G+ CE ++ P +C++ G C G+C C GW G +C+ PL C +
Sbjct: 616 -PGYKGEICEEEDCLDP-----MCSNHGICVKGECHCSTGWGGVNCETPL--PVCQEQ-- 665
Query: 588 GICNGRGH--CECGRCHCHQQSLYTDTICEI-NYSAIHPGLCEDLRSCVQC-QAWGTGEK 643
C+G G + G C C + +D E+ G+C R QC + W
Sbjct: 666 --CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCS--RGICQCEEGW----- 716
Query: 644 KGRTCEE--CNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG--DGAPG 693
G TCEE C+ E + ++ CS E D CT ++ ++ DG PG
Sbjct: 717 VGPTCEERSCH---SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 767
Score = 72.4 bits (176), Expect = 4e-12
Identities = 73/286 (25%), Positives = 110/286 (38%), Gaps = 51/286 (17%)
Query: 424 CQLPEDQKGNIHLKPS-FSDGLKMDAGIIC------DVCTCELQKEVRSARCSFNGDFVC 476
C +PE+Q + P+ F G + IC ++C +++ CS +G V
Sbjct: 589 CDVPEEQC----IDPTCFGHGTCIMGVCICVPGYKGEICE---EEDCLDPMCSNHGICVK 641
Query: 477 GQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFC 536
G+C CS GW G C + + C + CSG G VC + ++ G C
Sbjct: 642 GECHCSTGWGGVNCE------TPLPVCQEQ-----CSGHGTFLLDAGVCSCDPKWTGSDC 690
Query: 537 EYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHC 596
+ C G CS G C CE GW GP+C+ +C C G C
Sbjct: 691 STE------LCTMECGSHGVCSRGICQCEEGWVGPTCE----ERSCHSH----CTEHGQC 736
Query: 597 ECGRCHCHQQSLYTDTICEINY--SAIH---PGLCEDLRSCVQCQ-AWGTGEKKGRTCEE 650
+ G+C C + C I + A+ PGLC C Q W + G +
Sbjct: 737 KDGKCECSPG--WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 794
Query: 651 CNFKVKMV--DELKRAEEVVVRCSFRD--EDDDCTYSYTMEGDGAP 692
CN ++M+ D L + + C D + +C S +G P
Sbjct: 795 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840
Score = 72.0 bits (175), Expect = 5e-12
Identities = 49/138 (35%), Positives = 59/138 (42%), Gaps = 17/138 (12%)
Query: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571
C+G GEC GHC C+ + G C D+ CP LC G G CVC GW GP
Sbjct: 536 CNGNGECISGHCHCFPG--FLGPDCARDS--CP----VLCGGNGEYEKGHCVCRHGWKGP 587
Query: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHPGLCEDLRS 631
CD P CID C G G C G C C Y ICE + P +C +
Sbjct: 588 ECDVP--EEQCIDPT---CFGHGTCIMGVCICVPG--YKGEICE-EEDCLDP-MCSNHGI 638
Query: 632 CVQCQAWGTGEKKGRTCE 649
CV+ + + G CE
Sbjct: 639 CVKGECHCSTGWGGVNCE 656
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 90.5 bits (223), Expect = 1e-17
Identities = 70/224 (31%), Positives = 93/224 (41%), Gaps = 54/224 (24%)
Query: 468 CSFNGDFVCGQCVCSEGWSGQTCN-------CSTGSLSDIQPCLRE----GED------- 509
CS +G V GQCVC EG++G+ C+ C + C+ E G D
Sbjct: 412 CSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCP 471
Query: 510 KPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWT 569
C G C G CVC + Y G+ C + QCPR C++RG C GQCVCE G+T
Sbjct: 472 NDCHQHGRCVNGMCVC--DDGYTGEDCR--DRQCPRD----CSNRGLCVDGQCVCEDGFT 523
Query: 570 GPSC---DCP--------LSNATCIDSNGGI------------CNGRGHCECGRCHCHQQ 606
GP C CP N C+ G + C+G+G C G+C CH+
Sbjct: 524 GPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEG 583
Query: 607 SLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEE 650
+T C + P C +L CV + G C E
Sbjct: 584 --FTGLDCGQHSC---PSDCNNLGQCVSGRCICNEGYSGEDCSE 622
Score = 76.3 bits (186), Expect = 3e-13
Identities = 65/202 (32%), Positives = 87/202 (43%), Gaps = 41/202 (20%)
Query: 424 CQLPEDQKGNIHLKPSFSDGLKM-DAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCS 482
C PE GN HL+ DG + D G + C+ + + C+ G V G C+C
Sbjct: 185 CSEPECP-GNCHLRGRCIDGQCICDDGFTGEDCS----QLACPSDCNDQGKCVNGVCICF 239
Query: 483 EGWSGQTCN---CSTGSLSDIQPCLR---------EGED--KP-----CSGRGECQCGHC 523
EG++G C+ C + C+ G+D KP C RG C C
Sbjct: 240 EGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENEC 299
Query: 524 VCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCI 583
VC EG + G+ C CP C DRGRC G C CE G+TG C P TC
Sbjct: 300 VC-DEG-FTGEDCS--ELICPND----CFDRGRCINGTCYCEEGFTGEDCGKP----TCP 347
Query: 584 DSNGGICNGRGHCECGRCHCHQ 605
+ C+ +G CE G+C C +
Sbjct: 348 HA----CHTQGRCEEGQCVCDE 365
Score = 73.6 bits (179), Expect = 2e-12
Identities = 63/235 (26%), Positives = 90/235 (38%), Gaps = 49/235 (20%)
Query: 454 VCTC-------ELQKEVRSARCSF-NGDFVCGQCVCSEGWSGQTCN-------CSTGSLS 498
VC C + +E+ CS +G V G CVC +G++G CN C
Sbjct: 235 VCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRC 294
Query: 499 DIQPCLRE----GED-------KPCSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTS 547
C+ + GED C RG C G C C E + G+ C CP
Sbjct: 295 VENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYC--EEGFTGEDCGKPT--CPHA- 349
Query: 548 GFLCNDRGRCSMGQCVCEPGWTGPSCD---CPL---SNATCIDSNGGICNGRGHCECGRC 601
C+ +GRC GQCVC+ G+ G C CP + C+D +G +CG
Sbjct: 350 ---CHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGEL 406
Query: 602 HC------HQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEE 650
C H + + +C+ Y+ C LR C + G + CE+
Sbjct: 407 KCPNGCSGHGRCVNGQCVCDEGYTGED---CSQLRCPNDCHSRGRCVEGKCVCEQ 458
Score = 72.0 bits (175), Expect = 5e-12
Identities = 63/217 (29%), Positives = 82/217 (37%), Gaps = 67/217 (30%)
Query: 468 CSFNGDFV---CGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSG----RGECQC 520
CS G+F CG CVC GW G C+ + C G RG C
Sbjct: 161 CSGRGNFSTEGCG-CVCEPGWKGPNCS-----------------EPECPGNCHLRGRCID 202
Query: 521 GHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCD---CPL 577
G C+C + + G+ C CP CND+G+C G C+C G+ G C CP+
Sbjct: 203 GQCIC--DDGFTGEDCS--QLACPSD----CNDQGKCVNGVCICFEGYAGADCSREICPV 254
Query: 578 ----SNATCIDS--------NGGICN---------GRGHCECGRCHCHQQSLYTDTICEI 616
+ TC+D G CN RG C C C + +T C
Sbjct: 255 PCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEG--FTGEDCS- 311
Query: 617 NYSAIHPGLCEDLRSCVQ----CQAWGTGEKKGR-TC 648
I P C D C+ C+ TGE G+ TC
Sbjct: 312 --ELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTC 346
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 1639 STPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPE 1698
S S P LV T ++ +++ L+W+ R + YLV GG FRV GD +
Sbjct: 621 SEVSPPKDLVVTEVTEETVNLAWDNEMR----VTEYLVVYTPTHEGGLEMQFRVPGD--Q 674
Query: 1699 SRLTVPGLSENVPYKFKVQA 1718
+ + L V Y +V A
Sbjct: 675 TSTIIQELEPGVEYFIRVFA 694
Score = 31.2 bits (69), Expect = 9.6
Identities = 52/220 (23%), Positives = 81/220 (36%), Gaps = 38/220 (17%)
Query: 1529 DTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVE 1588
DTP L S TSL + W+ P + Y + Y L G+ + +P TS V+
Sbjct: 986 DTPKDLQVSETAETSLTLLWKTPLAK--FDRYRLNYSLPT-GQWVGVQLPRNT-TSYVLR 1041
Query: 1589 DLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAP--GP 1646
L P G+E ++T E H P + ST AP
Sbjct: 1042 GLEP----------------GQEYNVLLTAEKGRHKSKP------ARVKASTEQAPELEN 1079
Query: 1647 LVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGL 1706
L T + D L+L+W + +++ + A A V G + +PGL
Sbjct: 1080 LTVTEVGWDGLRLNWTAADQA---YEHFIIQVQEANKVEAARNLTVPGSL--RAVDIPGL 1134
Query: 1707 SENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLG 1746
PY + +G+ R +++ E+ G P LG
Sbjct: 1135 KAATPYTVSIYG-VIQGY---RTPVLSAEAST-GETPNLG 1169
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 89.7 bits (221), Expect = 2e-17
Identities = 133/593 (22%), Positives = 208/593 (35%), Gaps = 94/593 (15%)
Query: 1186 LYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGR-LAFNVVSSTVTQLSWAEPA 1244
L P+ +Y +V A + G GP S V RT ++ PS P R + ++S++ + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE 438
Query: 1245 ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGA 1304
E NG + Y V Y D RP K D + + +L Y V A
Sbjct: 439 EPNGLVRGYRVYY--TPDSRRPPNAWHKHNTD--AGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 1305 GWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDS-------------FLMYSD 1351
G GP I Q K +P P D Q+ + D+ +MY
Sbjct: 495 GDGPPSPTI-----QVKTQQGVPAQP----ADFQAEVESDTRIQLSWLLPPQERIIMYEL 545
Query: 1352 DVLRSPSGSQRPSVSDDTGCGWKFEPLLGEELDLRRVTWRLPPEL---IPRLSASSGRSS 1408
+ Q+ V+ D + E L + L ++ R + P + A + +S+
Sbjct: 546 VYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQST 605
Query: 1409 DAEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAA 1468
P PP G + R + PP + S + + T + A
Sbjct: 606 ----PSAPPQKVMCVSMGSTTVRVSWVPPPAD----------------SRNGVITQYSVA 645
Query: 1469 Y--------GTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHD 1520
Y G H+ + S + +H+ P S+ V + +
Sbjct: 646 YEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDE 705
Query: 1521 SRLTAGVPDTPTRLV-FSALGPTSLRVSWQEP---RCERPLQGYSVEYQLLNGGELHRLN 1576
VP P R V L T++ V W+ P + ++GY V Y L GE L
Sbjct: 706 D-----VPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLP 760
Query: 1577 IPNPAQTS----VVVEDLLPNHSYVFRVRAQSQEGWG-REREGVITIESQVHPQSPLCPL 1631
I + + L P +Y V A + +G G R + ++T V
Sbjct: 761 IIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAV--------- 811
Query: 1632 PGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFR 1691
P P ++ T +L L W P+ G+++GY + A P T
Sbjct: 812 ---------PGRPTMMISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRADEARPNT--- 858
Query: 1692 VDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQ 1744
+D + TV GL + Y F++ A+ G G E E I FPQ
Sbjct: 859 IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQ 911
Score = 72.4 bits (176), Expect = 4e-12
Identities = 56/234 (23%), Positives = 96/234 (41%), Gaps = 23/234 (9%)
Query: 1128 GAPQNP---NAKAAGSRKIHFNWL-PPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVEL 1183
G P P A+ +I +WL PP + + Y + YW D + + + S L
Sbjct: 510 GVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTL 569
Query: 1184 TNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNV-VSSTVTQLSWAE 1242
+L P Y ++ A G G ++ + RT Q PS P + V + ST ++SW
Sbjct: 570 EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP 629
Query: 1243 PA--ETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKA 1300
P NG IT Y V Y V+ ++R + + ++ ++ +E E YR V+A
Sbjct: 630 PPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTE---YRVWVRA 686
Query: 1301 RNGAGWGPEREAII-------------NLATQPKRPMSIPIIPDIPIVDAQSGE 1341
G GPE ++ + +P ++ + +P+ Q G+
Sbjct: 687 HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ 740
Score = 70.9 bits (172), Expect = 1e-11
Identities = 65/231 (28%), Positives = 98/231 (42%), Gaps = 26/231 (11%)
Query: 1105 PDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPP---SGKPMGYRVKY 1161
P E R+ T + S PP + A+ + + W PP +G GYRV Y
Sbjct: 400 PSEAVRARTGEQAPSSPP--------RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYY 451
Query: 1162 WIQGDSESEA---HLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQE 1218
A H D+ + + + +L P Y ++V A+ A G+GP S + +T Q
Sbjct: 452 TPDSRRPPNAWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQG 510
Query: 1219 VPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNP 1278
VP++P V S T QLSW P + I YE+ Y D+++ KV D
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLPPQE--RIIMYELVYWAAEDEDQ----QHKVTFDPT 564
Query: 1279 KNRMLLIENLRESQPYRYTVKARNGAGWG---PEREAIINLATQPKRPMSI 1326
+ L E+L+ YR+ + AR+ G G P EA +T P +
Sbjct: 565 SSYTL--EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKV 613
Score = 59.3 bits (142), Expect = 3e-08
Identities = 59/231 (25%), Positives = 86/231 (37%), Gaps = 20/231 (8%)
Query: 1511 STLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG 1570
S+L + + +P P LV + TS+ ++W E P+ Y ++Y+ G
Sbjct: 302 SSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSE-PVTYYGIQYRAA-GT 359
Query: 1571 ELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCP 1630
E + A T + L P Y FRV A + G G E V + P SP
Sbjct: 360 EGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP--- 416
Query: 1631 LPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAF 1690
P + LS ++ + WE P PNG + GY V P A+
Sbjct: 417 -------------PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRV-YYTPDSRRPPNAW 462
Query: 1691 RVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1741
TV L + Y +V A T G GP I +++Q G P
Sbjct: 463 HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPP-SPTIQVKTQQGVP 512
Score = 52.4 bits (124), Expect = 4e-06
Identities = 46/194 (23%), Positives = 74/194 (38%), Gaps = 17/194 (8%)
Query: 1128 GAPQNPNAKAAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEA-----HLLDSK 1177
G P+ + S +H W P G+ GY+V Y + E ++ ++
Sbjct: 710 GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAE 769
Query: 1178 VPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQ 1237
++ L P Y + V AY +G+G S T VP P + +T
Sbjct: 770 AQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTAL- 828
Query: 1238 LSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYT 1297
L W P E GE+ Y + Y D+ RP + ++ + L + Y +
Sbjct: 829 LQWHPPKELPGELLGYRLQYCRA-DEARP-----NTIDFGKDDQHFTVTGLHKGTTYIFR 882
Query: 1298 VKARNGAGWGPERE 1311
+ A+N AG G E E
Sbjct: 883 LAAKNRAGLGEEFE 896
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,649,794
Number of Sequences: 37866
Number of extensions: 4181050
Number of successful extensions: 21370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 315
Number of HSP's that attempted gapping in prelim test: 15179
Number of HSP's gapped (non-prelim): 4242
length of query: 1822
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1705
effective length of database: 13,817,196
effective search space: 23558319180
effective search space used: 23558319180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.