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Search of human proteins with 5454166
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5454166 vesicle transport through interaction with t-SNAREs
1B [Homo sapiens]
(232 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5454166 vesicle transport through interaction with t-SNAREs 1... 449 e-127
gi|113374156 SNARE Vti1a-beta protein [Homo sapiens] 110 8e-25
gi|148746195 trichohyalin [Homo sapiens] 42 6e-04
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 41 8e-04
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 40 0.002
gi|166295204 hypothetical protein LOC80127 [Homo sapiens] 40 0.002
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 39 0.004
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 38 0.008
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 38 0.008
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 37 0.014
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 35 0.042
gi|153791839 sodium channel associated protein 1 [Homo sapiens] 35 0.042
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 35 0.055
gi|4504919 keratin 8 [Homo sapiens] 35 0.071
gi|31982906 cingulin-like 1 [Homo sapiens] 35 0.071
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 35 0.071
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 34 0.093
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 34 0.093
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 34 0.093
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 34 0.093
gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo sa... 34 0.093
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 34 0.12
gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso... 34 0.12
gi|4759188 syntaxin 8 [Homo sapiens] 34 0.12
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 34 0.12
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 34 0.12
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 34 0.12
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 33 0.16
gi|4759154 synaptosomal-associated protein 29 [Homo sapiens] 33 0.16
gi|63003894 hypothetical protein LOC154467 [Homo sapiens] 33 0.16
>gi|5454166 vesicle transport through interaction with t-SNAREs 1B
[Homo sapiens]
Length = 232
Score = 449 bits (1155), Expect = e-127
Identities = 232/232 (100%), Positives = 232/232 (100%)
Query: 1 MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLA 60
MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLA
Sbjct: 1 MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLA 60
Query: 61 EMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENE 120
EMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENE
Sbjct: 61 EMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENE 120
Query: 121 HMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSR 180
HMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSR
Sbjct: 121 HMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSR 180
Query: 181 LVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGLVYYKFFRSH 232
LVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGLVYYKFFRSH
Sbjct: 181 LVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGLVYYKFFRSH 232
>gi|113374156 SNARE Vti1a-beta protein [Homo sapiens]
Length = 217
Score = 110 bits (276), Expect = 8e-25
Identities = 58/188 (30%), Positives = 113/188 (60%), Gaps = 8/188 (4%)
Query: 39 EEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRST 98
+EKK+++ + +++ +EA E L +M+ E+R P R +++R+Y++++ KL + + +
Sbjct: 32 DEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRS 91
Query: 99 PLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQ 158
+ + R ++ + N ++QRA LL TE L R+++ +E ++IA ET+Q
Sbjct: 92 RIAYSDEVRNELL-------GDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQ 144
Query: 159 IGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSII-ILLEL 217
IG E++E L R++++R + RL T NL KS +IL M R++ N++LL I+ I++ +
Sbjct: 145 IGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVI 204
Query: 218 AILGGLVY 225
IL + +
Sbjct: 205 TILMAITF 212
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 41.6 bits (96), Expect = 6e-04
Identities = 44/158 (27%), Positives = 67/158 (42%), Gaps = 19/158 (12%)
Query: 25 LQGVPERLLGTAGT----EEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSK 80
LQ E+LLG +E++K R+ +E QQE + L E E+ R + +
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 81 LRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLN 140
L+ + L + RE R R + Y E E LQ + LL G E
Sbjct: 1026 LQQEEEQLLREEREKR----------RLQERERQYREEEE----LQQEEEQLL-GEERET 1070
Query: 141 RATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTK 178
R Q +ER +R E Q +++ E E+R + ER +
Sbjct: 1071 RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Score = 38.1 bits (87), Expect = 0.006
Identities = 45/185 (24%), Positives = 75/185 (40%), Gaps = 18/185 (9%)
Query: 9 EHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEK-----QQEANETLAEME 63
E E+L + R + + ER EE+K+L ++ E+ Q+E + L + E
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 64 EELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMN 123
EE R L + R R+++ +L +E R + + + E +
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 124 R-------LQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLER 176
R Q +R L+ E R Q ++R H E ++ E+ EE EQ ER
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREH----EEERREQELAEE--EQEQARER 696
Query: 177 TKSRL 181
KSR+
Sbjct: 697 IKSRI 701
Score = 37.0 bits (84), Expect = 0.014
Identities = 51/196 (26%), Positives = 74/196 (37%), Gaps = 20/196 (10%)
Query: 6 ASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEE 65
A E K ++ + E+LQ EE++K R E+Q E L + EE+
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQ-----------REEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 66 LRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRL 125
L R + R YRKD KL ++ R + Y E E L
Sbjct: 943 LLREEREKRR-RQERERQYRKD-KKLQQKEEQLLGEEPEKRRRQEREKKYREEEE----L 996
Query: 126 QSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTS 185
Q + LL+ E R Q ER +R E Q +++ E E+R ER R
Sbjct: 997 QQEEEQLLR-EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER--ERQYREE 1053
Query: 186 ENLSKSRKILRSMSRK 201
E L + + L R+
Sbjct: 1054 EELQQEEEQLLGEERE 1069
Score = 36.6 bits (83), Expect = 0.019
Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 20/168 (11%)
Query: 39 EEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRST 98
+E+++ R+ +E QQE + L E E R L R YRK+ +L +E
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELE---------RQYRKE-EELQQEEEQL 1093
Query: 99 PLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQ 158
L P R + E E LQ + LL+ E R Q +ER +R E Q
Sbjct: 1094 -LREEPEKRRRQERERQCREEEE---LQQEEEQLLR-EEREKRRRQELERQYREEEEVQQ 1148
Query: 159 IGSEIIEELGEQRDQLE-----RTKSRLVNTSENLSKSRKILRSMSRK 201
+++ E E+R + E R + L E L + + R R+
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERE 1196
Score = 28.5 bits (62), Expect = 5.1
Identities = 38/177 (21%), Positives = 74/177 (41%), Gaps = 25/177 (14%)
Query: 38 TEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRS 97
++E+K+L+R+ E+++ ET + EE + P LR +D R+ R
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP----LRRQERD-----RKFRE 1364
Query: 98 TPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETD 157
L GR + E + + R + +R L + + + ER ++ + D
Sbjct: 1365 EELRHQEQGRK------FLEEEQRLRRQERERKFLKE-----EQQLRCQEREQQLRQDRD 1413
Query: 158 QIGSEIIEELGEQ-RDQLERTKSRLVNTSEN----LSKSRKILRSMSRKVTTNKLLL 209
+ E ++L Q RD+ R + + V E L + +++ + RK + LL
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLL 1470
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 41.2 bits (95), Expect = 8e-04
Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 21/174 (12%)
Query: 31 RLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAK 90
R L E + L ++ QQ+ N L + E++ F MMSK R Y +++
Sbjct: 824 RFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRR---FEQEMMSKKRQYDQEIEN 880
Query: 91 LHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSI--ER 148
L ++ + T I +E EH NRL+ + + E Q++ R
Sbjct: 881 LEKQQKQT---------------IERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNR 925
Query: 149 SHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKV 202
+ E ++ E+ +EL ++R + E +S+ E + K ++ L +K+
Sbjct: 926 KKEVINEVEKAPKELRKELMKRRKE-ELAQSQHAQEQEFVQKQQQELDGSLKKI 978
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 40.0 bits (92), Expect = 0.002
Identities = 55/236 (23%), Positives = 95/236 (40%), Gaps = 47/236 (19%)
Query: 5 AASSEHFEKLHEIFRGLHEDLQGV----PERLLGTAGT--------EEKKKLIRDFDEKQ 52
A E EKL ++ L+G+ P L+G EE + I ++
Sbjct: 681 AMEKEATEKLRKLLASQSSGLRGLWDCLPADLVGERSAQSKAAESLEELRACISTLVDRH 740
Query: 53 QEANETLAEMEEE----------LRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTA 102
+EA + LA ++EE R S + P ++ +DL KL E+R+ + A
Sbjct: 741 REAQQVLARLQEENQQLRGSLSPCREPGTSLKAPASPQVAALEQDLGKLEEELRA--VQA 798
Query: 103 TPGGR----GDMKYGIYAVENEHMNRLQSQRAMLLQGTE----SLNRATQS--------I 146
T G+ G +K +Y E + L+++ A L+ E SL Q+ +
Sbjct: 799 TMSGKSQEIGKLKQLLYQA-TEEVAELRAREAASLRQHEKTRGSLVAQAQAWGQELKALL 857
Query: 147 ERSHRIATETDQIGSEIIEE------LGEQRDQLERTKSRLVNTSENLSKSRKILR 196
E+ + E ++ + EE L Q + ER S + SE K+ ++L+
Sbjct: 858 EKYNTACREVGRLREAVAEERRRSGDLAAQAAEQERQASEMRGRSEQFEKTAELLK 913
>gi|166295204 hypothetical protein LOC80127 [Homo sapiens]
Length = 529
Score = 39.7 bits (91), Expect = 0.002
Identities = 42/216 (19%), Positives = 92/216 (42%), Gaps = 20/216 (9%)
Query: 7 SSEHFEKLHEIFRGLHEDLQGV---PERLLGTAGTEEKKKLIRDFDEKQQEANETLAEME 63
+ E +KL + + +L+G + +G TE K +R F +++ + L +++
Sbjct: 110 AQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTE--LKAVRQFQKRKIQVERELDDLK 167
Query: 64 EELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGR-------GDMKYGIYA 116
E LR + + + ++ +L +E + D ++
Sbjct: 168 ENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFK 227
Query: 117 VENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEE----LGEQRD 172
EN++ LQ A L+ T++L + +Q ++ SH + +I +++E L +QR
Sbjct: 228 -ENDY---LQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRS 283
Query: 173 QLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLL 208
Q++ + ++VN LS K S K+ + ++
Sbjct: 284 QIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMI 319
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 38.9 bits (89), Expect = 0.004
Identities = 30/164 (18%), Positives = 67/164 (40%), Gaps = 13/164 (7%)
Query: 39 EEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRST 98
+E+++ IR+ +EK + E + E EE++R M K R+ K+H + +
Sbjct: 305 QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ----EEMMWEKEEKIRELEEKMHEQEKI- 359
Query: 99 PLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQ 158
R + + + Q Q A + + E + + I + E ++
Sbjct: 360 --------REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 159 IGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKV 202
E E++ EQ ++++ + ++ E + + K +R K+
Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 37.7 bits (86), Expect = 0.008
Identities = 45/203 (22%), Positives = 90/203 (44%), Gaps = 29/203 (14%)
Query: 13 KLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLS 72
+L E+ L L+ P++L T +KK EK+++ L M + +
Sbjct: 554 ELQEVISDLQSKLRLAPDKLKSTESELKKK-------EKRRDEMLGLVPMRQSIIDLKEK 606
Query: 73 FRNPMMSKLRNYRKDLAKLHREV--RSTPLTATPGGRGDMKYGI--------YAVENEHM 122
+ +KL+N +D+ +L ++ + T L K + + +E + +
Sbjct: 607 EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDV 666
Query: 123 NRLQSQRAMLLQGTESLNRATQSI-----ERSHRIATETDQI--GSEIIEELGEQRDQLE 175
R +Q+A LQG + L+R Q + E+ H++ T + +I ++I++ EQ L+
Sbjct: 667 ERKIAQQAAKLQGID-LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLK 725
Query: 176 RT----KSRLVNTSENLSKSRKI 194
T KS + S NL + +++
Sbjct: 726 STTNELKSEKLQISTNLQRRQQL 748
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 37.7 bits (86), Expect = 0.008
Identities = 45/203 (22%), Positives = 90/203 (44%), Gaps = 29/203 (14%)
Query: 13 KLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLS 72
+L E+ L L+ P++L T +KK EK+++ L M + +
Sbjct: 693 ELQEVISDLQSKLRLAPDKLKSTESELKKK-------EKRRDEMLGLVPMRQSIIDLKEK 745
Query: 73 FRNPMMSKLRNYRKDLAKLHREV--RSTPLTATPGGRGDMKYGI--------YAVENEHM 122
+ +KL+N +D+ +L ++ + T L K + + +E + +
Sbjct: 746 EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDV 805
Query: 123 NRLQSQRAMLLQGTESLNRATQSI-----ERSHRIATETDQI--GSEIIEELGEQRDQLE 175
R +Q+A LQG + L+R Q + E+ H++ T + +I ++I++ EQ L+
Sbjct: 806 ERKIAQQAAKLQGID-LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLK 864
Query: 176 RT----KSRLVNTSENLSKSRKI 194
T KS + S NL + +++
Sbjct: 865 STTNELKSEKLQISTNLQRRQQL 887
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 37.0 bits (84), Expect = 0.014
Identities = 41/201 (20%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 1 MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLA 60
M A H ++ E R L + E L G + + ++ Q+ +E +
Sbjct: 369 MEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAM---------WRQRMQQMSEQVH 419
Query: 61 EMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENE 120
+ EE + MS+++ LA+L ++ P P G +++ + A E E
Sbjct: 420 TLREE--------KECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQA-EAE 470
Query: 121 HMNR----LQSQRAMLLQGTESLNRATQ-------SIERSHRIATETDQIGSEIIEELGE 169
H+ + L Q +Q E L+R + +ER+ + E + +I+E +
Sbjct: 471 HLRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQN 530
Query: 170 QRDQLERTKSRLVNTSENLSK 190
R + R S+ E L++
Sbjct: 531 DRTTISRALSQNRELKEQLAE 551
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 35.4 bits (80), Expect = 0.042
Identities = 32/188 (17%), Positives = 75/188 (39%), Gaps = 9/188 (4%)
Query: 9 EHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRY 68
E +K E R E ++ E++ K+K + +E+ E E + E EE++R
Sbjct: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE 307
Query: 69 APLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVE---NEHMNRL 125
R ++R + + K + + + K ++ E E ++
Sbjct: 308 QEEQMRE-QEEQMREQEEQMGKQEEQ-----MWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 126 QSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTS 185
Q Q + + E + + + + + + ++ E E++GEQ++Q+ + ++
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Query: 186 ENLSKSRK 193
E + K +
Sbjct: 422 EQMRKQEE 429
>gi|153791839 sodium channel associated protein 1 [Homo sapiens]
Length = 688
Score = 35.4 bits (80), Expect = 0.042
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 24/181 (13%)
Query: 54 EANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRST---PLTATPGGRGDM 110
E ++ L E+ +L+Y M +L N K+ +LH E++ L A P G ++
Sbjct: 62 EYDKHLGELNGQLKYYQKQV-GEMKLQLENVIKENERLHSELKDAVEKKLEAFPLGT-EV 119
Query: 111 KYGIYAVENEHMNRLQSQRAML----LQGTESLNRATQSIERSHRIATETDQIGSEIIEE 166
IYA ++E + LQ Q + Q E +Q ++R H++ E + E
Sbjct: 120 GTDIYA-DDETVRNLQEQLQLANQEKTQAVELWQTVSQELDRLHKLYQEHMTEAQIHVFE 178
Query: 167 LGEQRDQL---ERTKSRLVNTSENLSKSRK-----------ILRSMSRKVTTNKLLLSII 212
+Q+DQL ++ +L T+EN+ + + I+ + +K+ KL L +
Sbjct: 179 SQKQKDQLFDFQQLTKQLHVTNENMEVTNQQFLKTVTEQSVIIEQLRKKLRQAKLELRVA 238
Query: 213 I 213
+
Sbjct: 239 V 239
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 35.0 bits (79), Expect = 0.055
Identities = 38/207 (18%), Positives = 84/207 (40%), Gaps = 21/207 (10%)
Query: 12 EKLHE---IFRG---LHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEE 65
EK+HE I+R +HE + + ++ EEK IR+ +EK +E E + EE+
Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK---IREQEEKIREQEEKMWRQEEK 539
Query: 66 LRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVE------- 118
+R +R K+ K + R+ + + + + ++ E
Sbjct: 540 IREQEEMWREE--EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 119 ---NEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLE 175
E ++ Q + + E + + I E +++ E E++GEQ +++
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 176 RTKSRLVNTSENLSKSRKILRSMSRKV 202
+ ++ E + + + +R +K+
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKI 684
Score = 32.3 bits (72), Expect = 0.35
Identities = 26/153 (16%), Positives = 62/153 (40%), Gaps = 10/153 (6%)
Query: 41 KKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPL 100
+++ IR+ +EK+QE E + + EE++R + + R+ K+ + T
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIR----EQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 101 TATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIG 160
G + K E ++Q Q + + E + + I E +++
Sbjct: 645 QEEKMGEQEEKM------CEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Query: 161 SEIIEELGEQRDQLERTKSRLVNTSENLSKSRK 193
E E++ EQ +++ + ++ E + + +
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 34.7 bits (78), Expect = 0.071
Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 5/140 (3%)
Query: 55 ANETLAEMEE--ELRYAPL-SFRNPMMSKLRNYRKDLAKLHREVR--STPLTATPGGRGD 109
AN + AE E +++Y L S LR + ++++++R + + G R
Sbjct: 271 ANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRAS 330
Query: 110 MKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGE 169
++ I E ++ A L + +L RA Q + R R E + + E+
Sbjct: 331 LEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIAT 390
Query: 170 QRDQLERTKSRLVNTSENLS 189
R LE +SRL + +N+S
Sbjct: 391 YRKLLEGEESRLESGMQNMS 410
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 34.7 bits (78), Expect = 0.071
Identities = 38/172 (22%), Positives = 77/172 (44%), Gaps = 25/172 (14%)
Query: 36 AGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREV 95
AGTE + KL+++ +EK Q +E L E R A L ++ + + D AK +
Sbjct: 818 AGTEMRVKLLQEENEKLQGRSEEL-----ERRVAQLQ------RQIEDLKGDEAKAKETL 866
Query: 96 RSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATE 155
+ G ++ + E + ++RA+ + + +Q+ + ++
Sbjct: 867 KKYE-----GEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQL--- 918
Query: 156 TDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKS-RKILRSMSRKVTTNK 206
SE ++E EQ++QL R K+ + N +L K+ K+ + M+ V ++
Sbjct: 919 -----SEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 965
Score = 33.5 bits (75), Expect = 0.16
Identities = 32/178 (17%), Positives = 79/178 (44%), Gaps = 16/178 (8%)
Query: 39 EEKKKLIRDFDEKQQEANETLAEMEEEL-------RYAPLSFRNPMMSKLRNYRKDLAKL 91
E+ ++L + + ++ +T+ ++++E+ R + L +N + R++LA++
Sbjct: 930 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 989
Query: 92 HREVRSTPLTATPGGRGDMKY-GIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSH 150
R+++ L A MK + E + Q + L + L + + +E
Sbjct: 990 QRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYEL 1049
Query: 151 RIATETDQIGSEIIEELGEQRDQLE------RTKSRLVNTSENLSKSRKILRSMSRKV 202
+ S +++++ ++ QLE R S L+ SE +S+SR+ + + ++
Sbjct: 1050 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLL--SERISRSREQMEQLRNEL 1105
Score = 28.1 bits (61), Expect = 6.7
Identities = 43/176 (24%), Positives = 75/176 (42%), Gaps = 35/176 (19%)
Query: 43 KLIRDFDEKQQEANETLAEMEEELRYAPLSFRNP-------------MMSKLRNYRK--D 87
+L DE +++ LAEM+ +L+ L M +LR+Y++ D
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQD 1029
Query: 88 LAKLHREVRSTPLTATPGGRGDMKYGIYAVEN---------EHMNRLQSQRAMLLQGTES 138
A R++ L D++Y + A + + M SQ M L+ E
Sbjct: 1030 EALTKRQLLEQTLK-------DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE--EE 1080
Query: 139 LNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKI 194
N + ER R + +Q+ +E+++E ++D LE K L +++L KSR I
Sbjct: 1081 RNNSDLLSERISRSREQMEQLRNELLQERAARQD-LECDKISLERQNKDL-KSRII 1134
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 34.7 bits (78), Expect = 0.071
Identities = 45/202 (22%), Positives = 80/202 (39%), Gaps = 33/202 (16%)
Query: 8 SEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKK--KLIRDFDEKQQEANETLAEMEEE 65
+ E+L ++R + + +L EKK LIRD ++ + +AE+++
Sbjct: 291 NNEIEELKTLYRSKQHETEETIRKL-------EKKVQTLIRDCQVIRETKEDQIAELKKI 343
Query: 66 LRYAPLSFRNPMMSKLRN-------YRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVE 118
+ S N KL N + DL K H E L D + +E
Sbjct: 344 CEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLE-------DTNVRLNKME 396
Query: 119 NEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEI----------IEELG 168
+E+M + QS M+ + + + T E S+ + Q +E+ ++E+
Sbjct: 397 SEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVK 456
Query: 169 EQRDQLERTKSRLVNTSENLSK 190
+R+ L + K LVN E K
Sbjct: 457 ARRNTLHKEKDHLVNDYEQNMK 478
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 34.3 bits (77), Expect = 0.093
Identities = 39/185 (21%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 5 AASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEE 64
A +E ++L R L ++L T E++++L+ ++KQ++ ++ LAE +
Sbjct: 1434 AEKTETVDRLERGRRRLQQELDDA------TMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1487
Query: 65 ELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNR 124
+ + + R + RE R+ LT + + E E NR
Sbjct: 1488 AV----------LRAVEERERAEAEGREREARALSLTRALEEEQEARE-----ELERQNR 1532
Query: 125 -LQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVN 183
L+++ LL + + ++ +ER+ R+A + + EL ++ E K RL
Sbjct: 1533 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1592
Query: 184 TSENL 188
T + L
Sbjct: 1593 TVQAL 1597
Score = 29.6 bits (65), Expect = 2.3
Identities = 37/174 (21%), Positives = 72/174 (41%), Gaps = 30/174 (17%)
Query: 39 EEKKKL------IRDFDEKQQEANETLAE------MEEELRYAPLSFRNPMMSKLRNYRK 86
EEK++L + + E++Q +E L + ++ E LS +K + R+
Sbjct: 1754 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1813
Query: 87 DLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSI 146
L + +E+R G R K I A+E++ L Q E L + T+
Sbjct: 1814 QLERQIQELRGRLGEEDAGARARHKMTIAALESK-----------LAQAEEQLEQETRER 1862
Query: 147 ERSHRIATETDQIGSEIIEELGEQ-------RDQLERTKSRLVNTSENLSKSRK 193
S ++ ++ E++ ++ E+ RDQLE+ R+ L ++ +
Sbjct: 1863 ILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEE 1916
Score = 28.1 bits (61), Expect = 6.7
Identities = 33/160 (20%), Positives = 72/160 (45%), Gaps = 9/160 (5%)
Query: 40 EKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREV---- 95
E+++ ++ ++ + + T+A+ME+ LR R + R + ++L ++
Sbjct: 1042 EEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG-RQELEKLKRRLDGESSELQEQMVEQQ 1100
Query: 96 -RSTPLTATPGGR-GDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIA 153
R+ L A G + +++ + E+E R Q ++ L + +L A + +E
Sbjct: 1101 QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS-LREAQAALAEAQEDLESERVAR 1159
Query: 154 TETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRK 193
T+ ++ ++ EEL R +LE T N + L R+
Sbjct: 1160 TKAEKQRRDLGEELEALRGELEDTLDS-TNAQQELRSKRE 1198
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 34.3 bits (77), Expect = 0.093
Identities = 39/185 (21%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 5 AASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEE 64
A +E ++L R L ++L T E++++L+ ++KQ++ ++ LAE +
Sbjct: 1426 AEKTETVDRLERGRRRLQQELDDA------TMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1479
Query: 65 ELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNR 124
+ + + R + RE R+ LT + + E E NR
Sbjct: 1480 AV----------LRAVEERERAEAEGREREARALSLTRALEEEQEARE-----ELERQNR 1524
Query: 125 -LQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVN 183
L+++ LL + + ++ +ER+ R+A + + EL ++ E K RL
Sbjct: 1525 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1584
Query: 184 TSENL 188
T + L
Sbjct: 1585 TVQAL 1589
Score = 29.6 bits (65), Expect = 2.3
Identities = 37/174 (21%), Positives = 72/174 (41%), Gaps = 30/174 (17%)
Query: 39 EEKKKL------IRDFDEKQQEANETLAE------MEEELRYAPLSFRNPMMSKLRNYRK 86
EEK++L + + E++Q +E L + ++ E LS +K + R+
Sbjct: 1746 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1805
Query: 87 DLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSI 146
L + +E+R G R K I A+E++ L Q E L + T+
Sbjct: 1806 QLERQIQELRGRLGEEDAGARARHKMTIAALESK-----------LAQAEEQLEQETRER 1854
Query: 147 ERSHRIATETDQIGSEIIEELGEQ-------RDQLERTKSRLVNTSENLSKSRK 193
S ++ ++ E++ ++ E+ RDQLE+ R+ L ++ +
Sbjct: 1855 ILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEE 1908
Score = 28.1 bits (61), Expect = 6.7
Identities = 33/160 (20%), Positives = 72/160 (45%), Gaps = 9/160 (5%)
Query: 40 EKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREV---- 95
E+++ ++ ++ + + T+A+ME+ LR R + R + ++L ++
Sbjct: 1034 EEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG-RQELEKLKRRLDGESSELQEQMVEQQ 1092
Query: 96 -RSTPLTATPGGR-GDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIA 153
R+ L A G + +++ + E+E R Q ++ L + +L A + +E
Sbjct: 1093 QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS-LREAQAALAEAQEDLESERVAR 1151
Query: 154 TETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRK 193
T+ ++ ++ EEL R +LE T N + L R+
Sbjct: 1152 TKAEKQRRDLGEELEALRGELEDTLDS-TNAQQELRSKRE 1190
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 34.3 bits (77), Expect = 0.093
Identities = 39/185 (21%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 5 AASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEE 64
A +E ++L R L ++L T E++++L+ ++KQ++ ++ LAE +
Sbjct: 1467 AEKTETVDRLERGRRRLQQELDDA------TMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1520
Query: 65 ELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNR 124
+ + + R + RE R+ LT + + E E NR
Sbjct: 1521 AV----------LRAVEERERAEAEGREREARALSLTRALEEEQEARE-----ELERQNR 1565
Query: 125 -LQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVN 183
L+++ LL + + ++ +ER+ R+A + + EL ++ E K RL
Sbjct: 1566 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1625
Query: 184 TSENL 188
T + L
Sbjct: 1626 TVQAL 1630
Score = 29.6 bits (65), Expect = 2.3
Identities = 37/174 (21%), Positives = 72/174 (41%), Gaps = 30/174 (17%)
Query: 39 EEKKKL------IRDFDEKQQEANETLAE------MEEELRYAPLSFRNPMMSKLRNYRK 86
EEK++L + + E++Q +E L + ++ E LS +K + R+
Sbjct: 1787 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1846
Query: 87 DLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSI 146
L + +E+R G R K I A+E++ L Q E L + T+
Sbjct: 1847 QLERQIQELRGRLGEEDAGARARHKMTIAALESK-----------LAQAEEQLEQETRER 1895
Query: 147 ERSHRIATETDQIGSEIIEELGEQ-------RDQLERTKSRLVNTSENLSKSRK 193
S ++ ++ E++ ++ E+ RDQLE+ R+ L ++ +
Sbjct: 1896 ILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEE 1949
Score = 28.1 bits (61), Expect = 6.7
Identities = 33/160 (20%), Positives = 72/160 (45%), Gaps = 9/160 (5%)
Query: 40 EKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREV---- 95
E+++ ++ ++ + + T+A+ME+ LR R + R + ++L ++
Sbjct: 1075 EEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG-RQELEKLKRRLDGESSELQEQMVEQQ 1133
Query: 96 -RSTPLTATPGGR-GDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIA 153
R+ L A G + +++ + E+E R Q ++ L + +L A + +E
Sbjct: 1134 QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS-LREAQAALAEAQEDLESERVAR 1192
Query: 154 TETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRK 193
T+ ++ ++ EEL R +LE T N + L R+
Sbjct: 1193 TKAEKQRRDLGEELEALRGELEDTLDS-TNAQQELRSKRE 1231
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 34.3 bits (77), Expect = 0.093
Identities = 49/249 (19%), Positives = 91/249 (36%), Gaps = 43/249 (17%)
Query: 4 SAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKK--KLIRDFDEKQQEANETLAE 61
S S + EK + G ++Q E G EE K ++ + + + E + LAE
Sbjct: 1568 SGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAE 1627
Query: 62 MEEEL------------------------RYAPLSFRNPMMSKLRNYRKDLAKLHRE--- 94
+EE R L + M L + L R+
Sbjct: 1628 KDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATE 1687
Query: 95 ------VRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIER 148
+ L GR D + + A +E L+ + ++L E L A + ER
Sbjct: 1688 AQAATRLMQAQLKEEQAGR-DEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGER 1746
Query: 149 SHRIATE-----TDQIGSEIIEELG--EQRDQLERTKSRLVNTSENLSKSRKILRSMSRK 201
S R+A + T+++ + G Q+ +LE ++L E ++ R+ ++K
Sbjct: 1747 SRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKK 1806
Query: 202 VTTNKLLLS 210
T+ +++
Sbjct: 1807 AITDAAMMA 1815
>gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo
sapiens]
Length = 669
Score = 34.3 bits (77), Expect = 0.093
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 15/157 (9%)
Query: 45 IRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLA-KLHREVRSTPLTAT 103
+RD + + Q+ ++L E E + A + + R+D A + R R+ L
Sbjct: 333 LRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQAQRAQRAQQL--- 389
Query: 104 PGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHR-IATETDQIGSE 162
++ ++ ++ E +LQ A LLQ E L R ++ER R + ++ E
Sbjct: 390 ------LQLQVFQLQQEK-RQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKWE 442
Query: 163 IIEELGE---QRDQLERTKSRLVNTSENLSKSRKILR 196
+ ++ GE + QL+ +++ LV L R LR
Sbjct: 443 VCQKSGEISLLKQQLKESQAELVQKGSELVALRVALR 479
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 33.9 bits (76), Expect = 0.12
Identities = 40/174 (22%), Positives = 66/174 (37%), Gaps = 28/174 (16%)
Query: 16 EIFRGLHEDLQGVPERLLG--------TAGTEEKKKLIRDFDEKQQEANETLAEMEEELR 67
E L D Q + ERL A E+++ L +K +E + E+EEEL
Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 68 YAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQS 127
+K+ R DL++ E+ A GG ++ + + Q
Sbjct: 1124 A-----ERTARAKVEKLRSDLSRELEEISERLEEA--GGATSVQI---EMNKKREAEFQK 1173
Query: 128 QRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRL 181
R L + T ++ + H ++ + ELGEQ D L+R K +L
Sbjct: 1174 MRRDLEEATLQHEATAAALRKKH----------ADSVAELGEQIDNLQRVKQKL 1217
>gi|33356544 phosphoinositide-specific phospholipase C beta 1 isoform
b [Homo sapiens]
Length = 1173
Score = 33.9 bits (76), Expect = 0.12
Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 12/116 (10%)
Query: 9 EHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQE-----ANETLAEME 63
EH + L + + E+ Q + L +EKK+L + D+K+QE ++ ++ME
Sbjct: 1033 EHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQME 1092
Query: 64 EELRYAPLSFRNPMMSKLRNY-------RKDLAKLHREVRSTPLTATPGGRGDMKY 112
EE S+ ++ ++ ++ L + H+E+R L P G G +
Sbjct: 1093 EEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKGEGSSSF 1148
>gi|4759188 syntaxin 8 [Homo sapiens]
Length = 236
Score = 33.9 bits (76), Expect = 0.12
Identities = 18/64 (28%), Positives = 34/64 (53%)
Query: 152 IATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSI 211
I + Q+G EI EL EQ + ++ + + NT E L + + + RK + +++ I
Sbjct: 161 IISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRVNMVDRKSASCGMIMVI 220
Query: 212 IILL 215
++LL
Sbjct: 221 LLLL 224
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 33.9 bits (76), Expect = 0.12
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 3/106 (2%)
Query: 118 ENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERT 177
EN+H N QS ++ E + + S E +AT Q E IE+L + E++
Sbjct: 205 ENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLATLEKQ---ETIEQLLSNMFEGEQS 261
Query: 178 KSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGL 223
+S +V+ + L + R S VT N S+ LEL G L
Sbjct: 262 QSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLELLAQGAL 307
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 33.9 bits (76), Expect = 0.12
Identities = 45/205 (21%), Positives = 89/205 (43%), Gaps = 21/205 (10%)
Query: 23 EDLQGVPERLLGTAGTEEK-----KKLIRDFDEKQQEANE-TLAEMEEELRYAPLSFRNP 76
+ LQ E A EEK K+++ +++Q+EA E LA +E R++ L +
Sbjct: 967 QKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLER--RHSALQRHST 1024
Query: 77 MMSKLRNYRKDLAKLHREVRS---------TPLTATPGGRGDMKYGIYAVENE--HMNRL 125
+ ++ R+ LA L+ R A + ++Y I ++ + ++ +
Sbjct: 1025 LGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGV 1084
Query: 126 QSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTS 185
Q L+G + + S E+SH + +I + I EE+ + L R S +TS
Sbjct: 1085 QKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTS 1144
Query: 186 ENLSKSRKILR--SMSRKVTTNKLL 208
+ K + L ++ RK+ +++
Sbjct: 1145 ADTMKDNEKLHNGTIQRKLKYERMV 1169
Score = 27.7 bits (60), Expect = 8.7
Identities = 31/157 (19%), Positives = 63/157 (40%), Gaps = 12/157 (7%)
Query: 39 EEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAK--LHREVR 96
E K+KLI + +EKQ+ L M++E+ + ++R + L + H E +
Sbjct: 610 ESKRKLIEEMEEKQKSDKAELERMQQEVE-TQRKETEIVQLQIRKQEESLKRRSFHIENK 668
Query: 97 STPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATET 156
L A K+ + + LQ +R Q E+ R + ++R +
Sbjct: 669 LKDLLAE-----KEKFEEERLREQQEIELQKKR----QEEETFLRVQEELQRLKELNNNE 719
Query: 157 DQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRK 193
+I +EL + + + + ++L + L + K
Sbjct: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEK 756
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 33.9 bits (76), Expect = 0.12
Identities = 39/192 (20%), Positives = 77/192 (40%), Gaps = 16/192 (8%)
Query: 23 EDLQGVPERLLGTAGTEEKKKLIRDFDEKQ---QEANETLAEMEEELRYAPLSFRNPMMS 79
E L ++ L + T+EK ++ +E+Q QE E LA +E L + +
Sbjct: 716 ESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQKEVLESSIAHEKRKAKE 775
Query: 80 KLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHM------NRLQSQRAMLL 133
L + ++ + L + + + + A+E E NRL Q+ L
Sbjct: 776 ALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELE 835
Query: 134 ---QGTESLNR----ATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSE 186
Q + LN A +E + + + +L E +LE TK++++ E
Sbjct: 836 LKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEE 895
Query: 187 NLSKSRKILRSM 198
L +K+++++
Sbjct: 896 RLILQQKMVKAL 907
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 33.5 bits (75), Expect = 0.16
Identities = 42/193 (21%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 12 EKLHEIFRGLHEDLQGVPERLLGTAGTEEK-KKLIRDFDEKQQEANETLAEMEEELRYAP 70
++ E + L ++L + ++L GT +K + ++D EK + A + A+ E E+ A
Sbjct: 31 KQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEV--AS 88
Query: 71 LSFRNPMMSK-LRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQR 129
L+ R ++ + L ++ LA +++ A RG + +EN L+ +
Sbjct: 89 LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG-----MKVIENR---ALKDEE 140
Query: 130 AMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLS 189
M LQ + ++ + IA E D+ E+ +L LERT+ R S
Sbjct: 141 KMELQEIQ--------LKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCS 192
Query: 190 KSRKILRSMSRKV 202
+ + L++++ +
Sbjct: 193 ELEEELKNVTNNL 205
>gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]
Length = 258
Score = 33.5 bits (75), Expect = 0.16
Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 123 NRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLV 182
+R Q R +L+ E+ +T RS + E++++G EEL QR LERT+ +
Sbjct: 40 DRQQYLRQEVLRRAEATAASTS---RSLALMYESEKVGVASSEELARQRGVLERTEKMVD 96
Query: 183 NTSENLSKSRKILRSM 198
++L S+K + S+
Sbjct: 97 KMDQDLKISQKHINSI 112
>gi|63003894 hypothetical protein LOC154467 [Homo sapiens]
Length = 97
Score = 33.5 bits (75), Expect = 0.16
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 4/52 (7%)
Query: 169 EQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAIL 220
E R LE+ K+ L+N + N K K LR +RK +LLS+ I + L ++
Sbjct: 44 EARRSLEKEKNSLMNKASNYEKELKFLRQENRK----NMLLSVAIFILLTLV 91
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,392,920
Number of Sequences: 37866
Number of extensions: 300606
Number of successful extensions: 2017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 1730
Number of HSP's gapped (non-prelim): 426
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.