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Search of human proteins with 5453822
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453822 nuclear receptor subfamily 4, group A, member 2
[Homo sapiens]
(598 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 1240 0.0
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 652 0.0
gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof... 652 0.0
gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof... 652 0.0
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 610 e-175
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 610 e-175
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 375 e-104
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 199 8e-51
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 197 2e-50
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 196 4e-50
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 196 5e-50
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 196 5e-50
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 196 7e-50
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 188 1e-47
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 187 2e-47
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 187 2e-47
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 187 2e-47
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 187 2e-47
gi|238550159 estrogen-related receptor beta [Homo sapiens] 183 4e-46
gi|11415052 retinoid X receptor, beta [Homo sapiens] 181 2e-45
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 177 3e-44
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 175 9e-44
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 172 6e-43
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 171 2e-42
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 162 8e-40
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi... 157 2e-38
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 155 8e-38
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 155 8e-38
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 155 8e-38
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 155 8e-38
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 1240 bits (3209), Expect = 0.0
Identities = 598/598 (100%), Positives = 598/598 (100%)
Query: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSF 60
MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSF
Sbjct: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSF 60
Query: 61 STFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSV 120
STFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSV
Sbjct: 61 STFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSV 120
Query: 121 YYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQ 180
YYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQ
Sbjct: 121 YYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQ 180
Query: 181 SPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHA 240
SPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHA
Sbjct: 181 SPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHA 240
Query: 241 SQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL 300
SQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL
Sbjct: 241 SQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL 300
Query: 301 ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP 360
ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP
Sbjct: 301 ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP 360
Query: 361 PVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGW 420
PVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGW
Sbjct: 361 PVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGW 420
Query: 421 AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFG 480
AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFG
Sbjct: 421 AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFG 480
Query: 481 EWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVT 540
EWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVT
Sbjct: 481 EWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVT 540
Query: 541 FNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
FNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
Sbjct: 541 FNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 652 bits (1683), Expect = 0.0
Identities = 366/653 (56%), Positives = 440/653 (67%), Gaps = 82/653 (12%)
Query: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITAT--TSLP 58
MPCVQAQY SP G+S A+Q+YS EY+++ + P++ K +MDL +TEITAT TSLP
Sbjct: 12 MPCVQAQYSPSPPGSSYAAQTYS----SEYTTEIMNPDYTKLTMDLGSTEITATATTSLP 67
Query: 59 SFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSH------------- 105
S STF++ YS+ Y++KP C+YQM Q+ IKVE+ + +Y H H
Sbjct: 68 SISTFVEGYSSNYELKPSCVYQM----QRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQH 123
Query: 106 ----LPPQS---EEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDD----------PGS 148
+PP S +E++P S S+Y+K S P TPTTP F Q +WD+ PG
Sbjct: 124 QQPSIPPASSPEDEVLP-STSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGP 182
Query: 149 LHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPE--- 205
L + V T +R LF FK SPP P S G H+ +P
Sbjct: 183 LLDPPMKAVPTV--------AGARFPLFHFKPSPPHPPAPSPA----GGHHLGYDPTAAA 230
Query: 206 ----PAGSHHVVDGQTFAVPN-----PIRKPAS-MGFPGLQIGH---ASQLL--DTQVPS 250
P G+ Q A+ + P+ K A+ + FP L + AS LL +PS
Sbjct: 231 ALSLPLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPS 290
Query: 251 PPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 310
PPSR S S EG CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR
Sbjct: 291 PPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 350
Query: 311 RRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKS-----PQEPSPPSPPVSLI 365
RRNRCQYCRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPKS P +PSPPSPP+ ++
Sbjct: 351 RRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMM 410
Query: 366 SALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIP 425
+ALVRA DS P LDYSR+ D +G D +H+QQFY+LLT S+++ R WAEKIP
Sbjct: 411 NALVRALTDSTP--RDLDYSRY-CPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIP 467
Query: 426 GFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDS 485
GF DLPK DQ LL ESAFLELFVLRL+ RSN E K +FCNG+VLHRLQC+RGFGEW+DS
Sbjct: 468 GFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDS 527
Query: 486 IVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGG 545
I +FS NLQ++N+DI A +C++AL+M+TERHGLKEPKRVEEL NKI + LKDH + G
Sbjct: 528 IKDFSLNLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQ--SKGQ 585
Query: 546 LNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
P SK+LG L ELR +CT GLQRIFYLKLEDLV PP+IIDKLFLDTLPF
Sbjct: 586 ALEPTE-SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 637
>gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 652 bits (1683), Expect = 0.0
Identities = 366/653 (56%), Positives = 440/653 (67%), Gaps = 82/653 (12%)
Query: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITAT--TSLP 58
MPCVQAQY SP G+S A+Q+YS EY+++ + P++ K +MDL +TEITAT TSLP
Sbjct: 1 MPCVQAQYSPSPPGSSYAAQTYS----SEYTTEIMNPDYTKLTMDLGSTEITATATTSLP 56
Query: 59 SFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSH------------- 105
S STF++ YS+ Y++KP C+YQM Q+ IKVE+ + +Y H H
Sbjct: 57 SISTFVEGYSSNYELKPSCVYQM----QRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQH 112
Query: 106 ----LPPQS---EEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDD----------PGS 148
+PP S +E++P S S+Y+K S P TPTTP F Q +WD+ PG
Sbjct: 113 QQPSIPPASSPEDEVLP-STSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGP 171
Query: 149 LHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPE--- 205
L + V T +R LF FK SPP P S G H+ +P
Sbjct: 172 LLDPPMKAVPTV--------AGARFPLFHFKPSPPHPPAPSPA----GGHHLGYDPTAAA 219
Query: 206 ----PAGSHHVVDGQTFAVPN-----PIRKPAS-MGFPGLQIGH---ASQLL--DTQVPS 250
P G+ Q A+ + P+ K A+ + FP L + AS LL +PS
Sbjct: 220 ALSLPLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPS 279
Query: 251 PPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 310
PPSR S S EG CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR
Sbjct: 280 PPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 339
Query: 311 RRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKS-----PQEPSPPSPPVSLI 365
RRNRCQYCRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPKS P +PSPPSPP+ ++
Sbjct: 340 RRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMM 399
Query: 366 SALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIP 425
+ALVRA DS P LDYSR+ D +G D +H+QQFY+LLT S+++ R WAEKIP
Sbjct: 400 NALVRALTDSTP--RDLDYSRY-CPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIP 456
Query: 426 GFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDS 485
GF DLPK DQ LL ESAFLELFVLRL+ RSN E K +FCNG+VLHRLQC+RGFGEW+DS
Sbjct: 457 GFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDS 516
Query: 486 IVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGG 545
I +FS NLQ++N+DI A +C++AL+M+TERHGLKEPKRVEEL NKI + LKDH + G
Sbjct: 517 IKDFSLNLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQ--SKGQ 574
Query: 546 LNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
P SK+LG L ELR +CT GLQRIFYLKLEDLV PP+IIDKLFLDTLPF
Sbjct: 575 ALEPTE-SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626
>gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 652 bits (1683), Expect = 0.0
Identities = 366/653 (56%), Positives = 440/653 (67%), Gaps = 82/653 (12%)
Query: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITAT--TSLP 58
MPCVQAQY SP G+S A+Q+YS EY+++ + P++ K +MDL +TEITAT TSLP
Sbjct: 1 MPCVQAQYSPSPPGSSYAAQTYS----SEYTTEIMNPDYTKLTMDLGSTEITATATTSLP 56
Query: 59 SFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSH------------- 105
S STF++ YS+ Y++KP C+YQM Q+ IKVE+ + +Y H H
Sbjct: 57 SISTFVEGYSSNYELKPSCVYQM----QRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQH 112
Query: 106 ----LPPQS---EEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDD----------PGS 148
+PP S +E++P S S+Y+K S P TPTTP F Q +WD+ PG
Sbjct: 113 QQPSIPPASSPEDEVLP-STSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGP 171
Query: 149 LHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPE--- 205
L + V T +R LF FK SPP P S G H+ +P
Sbjct: 172 LLDPPMKAVPTV--------AGARFPLFHFKPSPPHPPAPSPA----GGHHLGYDPTAAA 219
Query: 206 ----PAGSHHVVDGQTFAVPN-----PIRKPAS-MGFPGLQIGH---ASQLL--DTQVPS 250
P G+ Q A+ + P+ K A+ + FP L + AS LL +PS
Sbjct: 220 ALSLPLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPS 279
Query: 251 PPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 310
PPSR S S EG CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR
Sbjct: 280 PPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 339
Query: 311 RRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKS-----PQEPSPPSPPVSLI 365
RRNRCQYCRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPKS P +PSPPSPP+ ++
Sbjct: 340 RRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMM 399
Query: 366 SALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIP 425
+ALVRA DS P LDYSR+ D +G D +H+QQFY+LLT S+++ R WAEKIP
Sbjct: 400 NALVRALTDSTP--RDLDYSRY-CPTDQAAAGTDAEHVQQFYNLLTASIDVSRSWAEKIP 456
Query: 426 GFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDS 485
GF DLPK DQ LL ESAFLELFVLRL+ RSN E K +FCNG+VLHRLQC+RGFGEW+DS
Sbjct: 457 GFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLVLHRLQCLRGFGEWLDS 516
Query: 486 IVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGG 545
I +FS NLQ++N+DI A +C++AL+M+TERHGLKEPKRVEEL NKI + LKDH + G
Sbjct: 517 IKDFSLNLQSLNLDIQALACLSALSMITERHGLKEPKRVEELCNKITSSLKDHQ--SKGQ 574
Query: 546 LNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
P SK+LG L ELR +CT GLQRIFYLKLEDLV PP+IIDKLFLDTLPF
Sbjct: 575 ALEPTE-SKVLGALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDTLPF 626
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 610 bits (1574), Expect = e-175
Identities = 339/634 (53%), Positives = 419/634 (66%), Gaps = 72/634 (11%)
Query: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEIT--ATTSLP 58
MPC+QAQYG+ P +SD LTPEF+K +MDL + E A T+LP
Sbjct: 1 MPCIQAQYGTPAPSPGPRDH---------LASDPLTPEFIKPTMDLASPEAAPAAPTALP 51
Query: 59 SFSTFMDNYSTGYDVKPPCLYQMP---------------------LSGQQSSIKVEDIQM 97
SFSTFMD Y+ +D LYQ+P S +S K ED Q+
Sbjct: 52 SFSTFMDGYTGEFDT---FLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQV 108
Query: 98 HNYQQHSHLPPQSEEMMPHSGSVYY-KPSSPPTPTTPGFQVQHSPMWDDPGSLHNF---- 152
+ L +E + SGS YY P S P+P+TP FQ WD GS +F
Sbjct: 109 YGCYP-GPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWD--GSFGHFSPSQ 165
Query: 153 -HQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPA-GSH 210
++ A T + + P + FSF SPP P S P+ P+ +H
Sbjct: 166 TYEGLRAWTEQLPKASGPPQPPAFFSF--SPPTGPSPSLAQS-------PLKLFPSQATH 216
Query: 211 HVVDGQTFAVPNPIRKPASMGFPGLQIG----HASQLLDTQVPSPPSR-GSPS-NEGLCA 264
+ +G+++++P FPGL S +LDT V S +R G+P +EG CA
Sbjct: 217 QLGEGESYSMPT--------AFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCA 268
Query: 265 VCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCL 324
VCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ+CRFQKCL
Sbjct: 269 VCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCL 328
Query: 325 AVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDY 384
AVGMVKEVVRTDSLKGRRGRLPSKPK P P + P +L+++LVRAH+DS P+ LDY
Sbjct: 329 AVGMVKEVVRTDSLKGRRGRLPSKPKQP----PDASPANLLTSLVRAHLDSGPSTAKLDY 384
Query: 385 SRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFL 444
S+FQ +D +QQFYDLL+GS+E+IR WAEKIPGFA+L ADQDLL ESAFL
Sbjct: 385 SKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFL 444
Query: 445 ELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFS 504
ELF+LRLAYRS P EGKLIFC+G+VLHRLQC RGFG+WIDSI+ FS +L ++ +D+ AF+
Sbjct: 445 ELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFA 504
Query: 505 CIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRT 564
C++AL ++T+RHGL+EP+RVEELQN+I +CLK+HV G + LS+LLGKLPELRT
Sbjct: 505 CLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRT 564
Query: 565 LCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
LCTQGLQRIFYLKLEDLVPPP IIDK+F+DTLPF
Sbjct: 565 LCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 610 bits (1574), Expect = e-175
Identities = 339/634 (53%), Positives = 419/634 (66%), Gaps = 72/634 (11%)
Query: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEIT--ATTSLP 58
MPC+QAQYG+ P +SD LTPEF+K +MDL + E A T+LP
Sbjct: 1 MPCIQAQYGTPAPSPGPRDH---------LASDPLTPEFIKPTMDLASPEAAPAAPTALP 51
Query: 59 SFSTFMDNYSTGYDVKPPCLYQMP---------------------LSGQQSSIKVEDIQM 97
SFSTFMD Y+ +D LYQ+P S +S K ED Q+
Sbjct: 52 SFSTFMDGYTGEFDT---FLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQV 108
Query: 98 HNYQQHSHLPPQSEEMMPHSGSVYY-KPSSPPTPTTPGFQVQHSPMWDDPGSLHNF---- 152
+ L +E + SGS YY P S P+P+TP FQ WD GS +F
Sbjct: 109 YGCYP-GPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWD--GSFGHFSPSQ 165
Query: 153 -HQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPA-GSH 210
++ A T + + P + FSF SPP P S P+ P+ +H
Sbjct: 166 TYEGLRAWTEQLPKASGPPQPPAFFSF--SPPTGPSPSLAQS-------PLKLFPSQATH 216
Query: 211 HVVDGQTFAVPNPIRKPASMGFPGLQIG----HASQLLDTQVPSPPSR-GSPS-NEGLCA 264
+ +G+++++P FPGL S +LDT V S +R G+P +EG CA
Sbjct: 217 QLGEGESYSMPT--------AFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCA 268
Query: 265 VCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCL 324
VCGDNA+CQHYGVRTCEGCKGFFKRTVQKNAKY+CLANK+CPVDKRRRNRCQ+CRFQKCL
Sbjct: 269 VCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCL 328
Query: 325 AVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDY 384
AVGMVKEVVRTDSLKGRRGRLPSKPK P P + P +L+++LVRAH+DS P+ LDY
Sbjct: 329 AVGMVKEVVRTDSLKGRRGRLPSKPKQP----PDASPANLLTSLVRAHLDSGPSTAKLDY 384
Query: 385 SRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFL 444
S+FQ +D +QQFYDLL+GS+E+IR WAEKIPGFA+L ADQDLL ESAFL
Sbjct: 385 SKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFL 444
Query: 445 ELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFS 504
ELF+LRLAYRS P EGKLIFC+G+VLHRLQC RGFG+WIDSI+ FS +L ++ +D+ AF+
Sbjct: 445 ELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFA 504
Query: 505 CIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRT 564
C++AL ++T+RHGL+EP+RVEELQN+I +CLK+HV G + LS+LLGKLPELRT
Sbjct: 505 CLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRT 564
Query: 565 LCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
LCTQGLQRIFYLKLEDLVPPP IIDK+F+DTLPF
Sbjct: 565 LCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 598
>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
c [Homo sapiens]
Length = 443
Score = 375 bits (964), Expect = e-104
Identities = 225/441 (51%), Positives = 272/441 (61%), Gaps = 78/441 (17%)
Query: 1 MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITAT--TSLP 58
MPCVQAQY SP G+S A+Q+YS EY+++ + P++ K +MDL +TEITAT TSLP
Sbjct: 1 MPCVQAQYSPSPPGSSYAAQTYS----SEYTTEIMNPDYTKLTMDLGSTEITATATTSLP 56
Query: 59 SFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSH------------- 105
S STF++ YS+ Y++KP C+YQM Q+ IKVE+ + +Y H H
Sbjct: 57 SISTFVEGYSSNYELKPSCVYQM----QRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQH 112
Query: 106 ----LPPQS---EEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDD----------PGS 148
+PP S +E++P S S+Y+K S P TPTTP F Q +WD+ PG
Sbjct: 113 QQPSIPPASSPEDEVLP-STSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGP 171
Query: 149 LHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPE--- 205
L + V T +R LF FK SPP P S G H+ +P
Sbjct: 172 LLDPPMKAVPTV--------AGARFPLFHFKPSPPHPPAPSPA----GGHHLGYDPTAAA 219
Query: 206 ----PAGSHHVVDGQTFAVPN-----PIRKPAS-MGFPGLQIGH---ASQLL--DTQVPS 250
P G+ Q A+ + P+ K A+ + FP L + AS LL +PS
Sbjct: 220 ALSLPLGAAAAAGSQAAALESHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPS 279
Query: 251 PPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 310
PPSR S S EG CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR
Sbjct: 280 PPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKR 339
Query: 311 RRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKS-----PQEPSPPSPPVSLI 365
RRNRCQYCRFQKCL+VGMVKEVVRTDSLKGRRGRLPSKPKS P +PSPPSPP+ ++
Sbjct: 340 RRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMM 399
Query: 366 SALVRAHVDSNPAMTSLDYSR 386
+ALVRA DS P LDYSR
Sbjct: 400 NALVRALTDSTP--RDLDYSR 418
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 199 bits (505), Expect = 8e-51
Identities = 119/363 (32%), Positives = 201/363 (55%), Gaps = 15/363 (4%)
Query: 239 HASQLLDTQ-------VPSPPSRGSPSNEGL-CAVCGDNAACQHYGVRTCEGCKGFFKRT 290
H +Q ++TQ VPSPPS P C VC D ++ HYGV CEGCKGFF+R+
Sbjct: 49 HTAQSIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRS 108
Query: 291 VQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPK 350
+QKN Y C +KNC ++K RNRCQYCR QKC VGM KE VR D + ++ + SK +
Sbjct: 109 IQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRND--RNKKKKETSKQE 166
Query: 351 SPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLL 410
+ + L + +AH ++ P++ L ++ D+++ D +F +L
Sbjct: 167 CTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVR-LDLGLWDKFSELA 225
Query: 411 TGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVL 470
T + I +A+++PGF L ADQ L ++A L++ +LR+ R P + + F +G+ L
Sbjct: 226 TKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 285
Query: 471 HRLQCVR-GFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQ 528
+R Q GFG D + F++ L + +D + ++A+ ++ +R L+EP +V++LQ
Sbjct: 286 NRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQ 345
Query: 529 NKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAII 588
++ LK ++ ++P+ K+L K+ +LR++ +G +R+ LK+E P +I
Sbjct: 346 EPLLEALKIYIRKRRP--SKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLI 403
Query: 589 DKL 591
++
Sbjct: 404 QEM 406
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 197 bits (502), Expect = 2e-50
Identities = 135/409 (33%), Positives = 216/409 (52%), Gaps = 35/409 (8%)
Query: 208 GSHHVVDGQTFAVPNPIR--------KPA--SMGFPGLQIGHASQLLDTQ-------VPS 250
GS + G FA P +R P+ +G P L AS ++TQ VPS
Sbjct: 17 GSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPS 76
Query: 251 PPSRGSPSNEGL-CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDK 309
PS P C VC D ++ HYGV +CEGCKGFF+R++QKN Y C +KNC ++K
Sbjct: 77 SPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINK 136
Query: 310 RRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVS-----L 364
RNRCQYCR QKC VGM KE VR D R K + +E SP S +S L
Sbjct: 137 VTRNRCQYCRLQKCFEVGMSKEAVRND-------RNKKKKEVKEEGSPDSYELSPQLEEL 189
Query: 365 ISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKI 424
I+ + +AH ++ P++ L ++ D+++ D +F +L T + I +A+++
Sbjct: 190 ITKVSKAHQETFPSLCQLGKYTTNSSADHRVQ-LDLGLWDKFSELATKCIIKIVEFAKRL 248
Query: 425 PGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVR-GFGEWI 483
PGF L ADQ L ++A L++ +LR+ R P + + F +G+ L+R Q GFG
Sbjct: 249 PGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLT 308
Query: 484 DSIVEFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIVNCLKDHVTFN 542
D + F+ L + +D + ++A+ ++ +R L+EP++V++LQ ++ L+ +
Sbjct: 309 DLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRR 368
Query: 543 NGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKL 591
++P ++L K+ +LR + T+G +R LK+E P P +I ++
Sbjct: 369 RP--SQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREM 415
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 196 bits (499), Expect = 4e-50
Identities = 129/382 (33%), Positives = 201/382 (52%), Gaps = 14/382 (3%)
Query: 223 PIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGS-PSNEGLCAVCGDNAACQHYGVRTCE 281
P+R P G I S + VPSPPS P C VC D ++ HYGV CE
Sbjct: 43 PLRTPLWNG-SNHSIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACE 101
Query: 282 GCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGR 341
GCKGFF+R++QKN Y C +KNC ++K RNRCQYCR QKC VGM KE VR D + +
Sbjct: 102 GCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRND--RNK 159
Query: 342 RGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQ 401
+ + KP+ + + LI + +AH ++ PA+ L N Q D
Sbjct: 160 KKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLG-KYTTNNSSEQRVSLDID 218
Query: 402 HIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGK 461
+F +L T + +A+++PGF L ADQ L ++A L++ +LR+ R P +
Sbjct: 219 LWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDT 278
Query: 462 LIFCNGVVLHRLQCVR-GFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVT-ERHGLK 519
+ F +G+ L+R Q GFG D + F++ L + +D + ++A+ ++ +R L+
Sbjct: 279 MTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLE 338
Query: 520 EPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLE 579
+P RV+ LQ ++ LK +V +RP+ K+L K+ +LR++ +G +R+ LK+E
Sbjct: 339 QPDRVDMLQEPLLEALKVYVRKRRP--SRPHMFPKMLMKITDLRSISAKGAERVITLKME 396
Query: 580 DLVPPPAIIDKLF-----LDTL 596
P +I ++ LDTL
Sbjct: 397 IPGSMPPLIQEMLENSEGLDTL 418
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 196 bits (498), Expect = 5e-50
Identities = 123/357 (34%), Positives = 193/357 (54%), Gaps = 13/357 (3%)
Query: 248 VPSPPSRGS-PSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCP 306
VPSPPS P C VC D ++ HYGV CEGCKGFF+R++QKN Y C +KNC
Sbjct: 72 VPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCI 131
Query: 307 VDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLIS 366
++K RNRCQYCR QKC VGM KE VR D + ++ + KP+ + + LI
Sbjct: 132 INKVTRNRCQYCRLQKCFEVGMSKESVRND--RNKKKKEVPKPECSESYTLTPEVGELIE 189
Query: 367 ALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPG 426
+ +AH ++ PA+ L N Q D +F +L T + +A+++PG
Sbjct: 190 KVRKAHQETFPALCQLG-KYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPG 248
Query: 427 FADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVR-GFGEWIDS 485
F L ADQ L ++A L++ +LR+ R P + + F +G+ L+R Q GFG D
Sbjct: 249 FTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDL 308
Query: 486 IVEFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIVNCLKDHVTFNNG 544
+ F++ L + +D + ++A+ ++ +R L++P RV+ LQ ++ LK +V
Sbjct: 309 VFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRP 368
Query: 545 GLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLF-----LDTL 596
+RP+ K+L K+ +LR++ +G +R+ LK+E P +I ++ LDTL
Sbjct: 369 --SRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTL 423
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 196 bits (498), Expect = 5e-50
Identities = 123/357 (34%), Positives = 193/357 (54%), Gaps = 13/357 (3%)
Query: 248 VPSPPSRGS-PSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCP 306
VPSPPS P C VC D ++ HYGV CEGCKGFF+R++QKN Y C +KNC
Sbjct: 72 VPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCI 131
Query: 307 VDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLIS 366
++K RNRCQYCR QKC VGM KE VR D + ++ + KP+ + + LI
Sbjct: 132 INKVTRNRCQYCRLQKCFEVGMSKESVRND--RNKKKKEVPKPECSESYTLTPEVGELIE 189
Query: 367 ALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPG 426
+ +AH ++ PA+ L N Q D +F +L T + +A+++PG
Sbjct: 190 KVRKAHQETFPALCQLG-KYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPG 248
Query: 427 FADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVR-GFGEWIDS 485
F L ADQ L ++A L++ +LR+ R P + + F +G+ L+R Q GFG D
Sbjct: 249 FTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDL 308
Query: 486 IVEFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIVNCLKDHVTFNNG 544
+ F++ L + +D + ++A+ ++ +R L++P RV+ LQ ++ LK +V
Sbjct: 309 VFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRP 368
Query: 545 GLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLF-----LDTL 596
+RP+ K+L K+ +LR++ +G +R+ LK+E P +I ++ LDTL
Sbjct: 369 --SRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTL 423
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 196 bits (497), Expect = 7e-50
Identities = 126/383 (32%), Positives = 210/383 (54%), Gaps = 24/383 (6%)
Query: 216 QTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHY 275
++FA P +PAS+ Q + +++ + PSPP P C VC D ++ HY
Sbjct: 39 ESFAWP----QPASLQSVETQSTSSEEMVPSS-PSPPP--PPRVYKPCFVCNDKSSGYHY 91
Query: 276 GVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRT 335
GV +CEGCKGFF+R++QKN Y C +KNC ++K RNRCQYCR QKC VGM KE VR
Sbjct: 92 GVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRN 151
Query: 336 DSLKGRRGRLPSKPKSPQEPSPPSPPVS-----LISALVRAHVDSNPAMTSLDYSRFQAN 390
D R K + +E SP S +S LI+ + +AH ++ P++ L ++
Sbjct: 152 D-------RNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSS 204
Query: 391 PDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLR 450
D+++ D +F +L T + I +A+++PGF L ADQ L ++A L++ +LR
Sbjct: 205 ADHRVQ-LDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLR 263
Query: 451 LAYRSNPVEGKLIFCNGVVLHRLQCVR-GFGEWIDSIVEFSSNLQNMNIDISAFSCIAAL 509
+ R P + + F +G+ L+R Q GFG D + F+ L + +D + ++A+
Sbjct: 264 ICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAI 323
Query: 510 AMVT-ERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQ 568
++ +R L+EP++V++LQ ++ L+ + ++P ++L K+ +LR + T+
Sbjct: 324 CLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRP--SQPYMFPRMLMKITDLRGISTK 381
Query: 569 GLQRIFYLKLEDLVPPPAIIDKL 591
G +R LK+E P P +I ++
Sbjct: 382 GAERAITLKMEIPGPMPPLIREM 404
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 188 bits (477), Expect = 1e-47
Identities = 129/418 (30%), Positives = 212/418 (50%), Gaps = 26/418 (6%)
Query: 165 QRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPI 224
Q +P+S LS PP + +SS GP + + P Q + NP+
Sbjct: 46 QLHSPISTLSSPINGMGPPFSVISSPM----GPHSMSVPTTPTLGFSTGSPQLSSPMNPV 101
Query: 225 RKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPS-NEGLCAVCGDNAACQHYGVRTCEGC 283
+ P +G L +VP+ PS S + +CA+CGD ++ +HYGV +CEGC
Sbjct: 102 SSSEDIKPP---LGLNGVL---KVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGC 155
Query: 284 KGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRG 343
KGFFKRTV+K+ Y C NK+C +DKR+RNRCQYCR+QKCLA+GM +E V+ + +G +
Sbjct: 156 KGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG-KD 214
Query: 344 RLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHI 403
R ++ +S + P + ++ A + P + + NP D +I
Sbjct: 215 RNENEVESTSSANEDMP----VERILEAELAVEPKTETYVEANMGLNP--SSPNDPVTNI 268
Query: 404 QQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLI 463
Q D + + WA++IP F++LP DQ +L + + EL + ++RS V+ ++
Sbjct: 269 CQAAD---KQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGIL 325
Query: 464 FCNGVVLHRLQC-VRGFGEWIDSIV-EFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKE 520
G+ +HR G G D ++ E S +++M +D + C+ A+ + + GL
Sbjct: 326 LATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSN 385
Query: 521 PKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKL 578
P VE L+ K+ L+ + +P +KLL +LP LR++ + L+ +F+ KL
Sbjct: 386 PAEVEALREKVYASLEAYCKHKYP--EQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 187 bits (475), Expect = 2e-47
Identities = 114/337 (33%), Positives = 182/337 (54%), Gaps = 11/337 (3%)
Query: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
LC VCGD A+ HYGV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF
Sbjct: 104 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 163
Query: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381
KCL VGM+KE VR D ++G GR K + E SP P L+ + + +
Sbjct: 164 KCLKVGMLKEGVRLDRVRG--GRQKYKRRIDAENSPYLNP-QLVQPAKKPYNKIVSHLLV 220
Query: 382 LDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFES 441
+ + A PD + D + + DL + +I GWA+ IPGF+ L ADQ L +S
Sbjct: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
Query: 442 AFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQNMNIDI 500
A++E+ +L + YRS E +L++ + ++ Q + G + ++I++ ++M ++
Sbjct: 281 AWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEK 340
Query: 501 SAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKL 559
F + A+A+ ++ +++ + V++LQ+ + L+D+ + + P K+L L
Sbjct: 341 EEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH--MEDPRRAGKMLMTL 398
Query: 560 PELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
P LR T+ +Q + +KLE VP + KLFL+ L
Sbjct: 399 PLLRQTSTKAVQHFYNIKLEGKVP----MHKLFLEML 431
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 187 bits (475), Expect = 2e-47
Identities = 114/337 (33%), Positives = 182/337 (54%), Gaps = 11/337 (3%)
Query: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
LC VCGD A+ HYGV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF
Sbjct: 104 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 163
Query: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381
KCL VGM+KE VR D ++G GR K + E SP P L+ + + +
Sbjct: 164 KCLKVGMLKEGVRLDRVRG--GRQKYKRRIDAENSPYLNP-QLVQPAKKPYNKIVSHLLV 220
Query: 382 LDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFES 441
+ + A PD + D + + DL + +I GWA+ IPGF+ L ADQ L +S
Sbjct: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
Query: 442 AFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQNMNIDI 500
A++E+ +L + YRS E +L++ + ++ Q + G + ++I++ ++M ++
Sbjct: 281 AWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEK 340
Query: 501 SAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKL 559
F + A+A+ ++ +++ + V++LQ+ + L+D+ + + P K+L L
Sbjct: 341 EEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH--MEDPRRAGKMLMTL 398
Query: 560 PELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
P LR T+ +Q + +KLE VP + KLFL+ L
Sbjct: 399 PLLRQTSTKAVQHFYNIKLEGKVP----MHKLFLEML 431
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 187 bits (475), Expect = 2e-47
Identities = 114/337 (33%), Positives = 182/337 (54%), Gaps = 11/337 (3%)
Query: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
LC VCGD A+ HYGV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF
Sbjct: 127 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 186
Query: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381
KCL VGM+KE VR D ++G GR K + E SP P L+ + + +
Sbjct: 187 KCLKVGMLKEGVRLDRVRG--GRQKYKRRIDAENSPYLNP-QLVQPAKKPYNKIVSHLLV 243
Query: 382 LDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFES 441
+ + A PD + D + + DL + +I GWA+ IPGF+ L ADQ L +S
Sbjct: 244 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 303
Query: 442 AFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQNMNIDI 500
A++E+ +L + YRS E +L++ + ++ Q + G + ++I++ ++M ++
Sbjct: 304 AWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEK 363
Query: 501 SAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKL 559
F + A+A+ ++ +++ + V++LQ+ + L+D+ + + P K+L L
Sbjct: 364 EEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH--MEDPRRAGKMLMTL 421
Query: 560 PELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
P LR T+ +Q + +KLE VP + KLFL+ L
Sbjct: 422 PLLRQTSTKAVQHFYNIKLEGKVP----MHKLFLEML 454
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 187 bits (475), Expect = 2e-47
Identities = 114/337 (33%), Positives = 182/337 (54%), Gaps = 11/337 (3%)
Query: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
LC VCGD A+ HYGV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF
Sbjct: 104 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 163
Query: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381
KCL VGM+KE VR D ++G GR K + E SP P L+ + + +
Sbjct: 164 KCLKVGMLKEGVRLDRVRG--GRQKYKRRIDAENSPYLNP-QLVQPAKKPYNKIVSHLLV 220
Query: 382 LDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFES 441
+ + A PD + D + + DL + +I GWA+ IPGF+ L ADQ L +S
Sbjct: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
Query: 442 AFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQNMNIDI 500
A++E+ +L + YRS E +L++ + ++ Q + G + ++I++ ++M ++
Sbjct: 281 AWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEK 340
Query: 501 SAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKL 559
F + A+A+ ++ +++ + V++LQ+ + L+D+ + + P K+L L
Sbjct: 341 EEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH--MEDPRRAGKMLMTL 398
Query: 560 PELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
P LR T+ +Q + +KLE VP + KLFL+ L
Sbjct: 399 PLLRQTSTKAVQHFYNIKLEGKVP----MHKLFLEML 431
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 183 bits (464), Expect = 4e-46
Identities = 116/345 (33%), Positives = 177/345 (51%), Gaps = 27/345 (7%)
Query: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
LC VCGD A+ HYGV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF
Sbjct: 102 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 161
Query: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEP------SPPS--PPVSLISALVRAHV 373
KCL VGM+KE VR D ++G R + + S P SPP+ P ++S L+ A
Sbjct: 162 KCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEP 221
Query: 374 DSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKA 433
D + A P M D + + DL + +I GWA+ IPGF+ L
Sbjct: 222 D-----------KLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLG 270
Query: 434 DQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSN 492
DQ L +SA++E+ +L + YRS P + KL++ ++ + G E +I++
Sbjct: 271 DQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRR 330
Query: 493 LQNMNIDISAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY 551
+ + ++ F + ALA+ ++ +++ + V++LQ+ + L+D+ P
Sbjct: 331 YKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRH--EEPWR 388
Query: 552 LSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
KLL LP LR + +Q + +KL+ VP + KLFL+ L
Sbjct: 389 TGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP----MHKLFLEML 429
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 181 bits (459), Expect = 2e-45
Identities = 132/428 (30%), Positives = 204/428 (47%), Gaps = 44/428 (10%)
Query: 181 SPPGTPVSSCQMRFDG----PLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPG-- 234
SPPG P+ G P PM P P GS V + P + PA GF G
Sbjct: 99 SPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPG-LPPPAPPGFSGPV 157
Query: 235 ----------LQIGHASQLLDTQVP---------SPPSRGSPSNEGLCAVCGDNAACQHY 275
L G + D + P PP G + + LCA+CGD ++ +HY
Sbjct: 158 SSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHY 217
Query: 276 GVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRT 335
GV +CEGCKGFFKRT++K+ Y C NK+C VDKR+RNRCQYCR+QKCLA GM +E V+
Sbjct: 218 GVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQE 277
Query: 336 DSLKG--RRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDY 393
+ +G + G +P+E P ++ A + S+ + + +
Sbjct: 278 ERQRGKDKDGDGEGAGGAPEE----MPVDRILEAELAVEQKSDQGVEGPGGTGGSGS--- 330
Query: 394 QMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAY 453
D +I Q D + + WA++IP F+ LP DQ +L + + EL + ++
Sbjct: 331 -SPNDPVTNICQAAD---KQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSH 386
Query: 454 RSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIV-EFSSNLQNMNIDISAFSCIAALAM 511
RS V ++ G+ +HR G G D ++ E S +++M +D + C+ A+ +
Sbjct: 387 RSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIIL 446
Query: 512 VT-ERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGL 570
+ GL P VE L+ K+ L+ + + +KLL +LP LR++ + L
Sbjct: 447 FNPDAKGLSNPSEVEVLREKVYASLETYC--KQKYPEQQGRFAKLLLRLPALRSIGLKCL 504
Query: 571 QRIFYLKL 578
+ +F+ KL
Sbjct: 505 EHLFFFKL 512
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 177 bits (448), Expect = 3e-44
Identities = 101/320 (31%), Positives = 168/320 (52%), Gaps = 18/320 (5%)
Query: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
+CA+CGD ++ +HYGV +CEGCKGFFKRT++K+ Y C NK+C +DKR+RNRCQYCR+Q
Sbjct: 138 ICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQ 197
Query: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381
KCL +GM +E V+ + R R + +S E + + ++ A + P
Sbjct: 198 KCLVMGMKREAVQEE-----RQRSRERAESEAECATSGHEDMPVERILEAELAVEP---- 248
Query: 382 LDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFES 441
+ ++ D M + + + WA++IP F+DL DQ +L +
Sbjct: 249 ----KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRA 304
Query: 442 AFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIV-EFSSNLQNMNID 499
+ EL + ++RS V+ ++ G+ +HR G G D ++ E S +++M +D
Sbjct: 305 GWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMD 364
Query: 500 ISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGK 558
S C+ A+ + + GL P VE L+ K+ L+ + +P +KLL +
Sbjct: 365 KSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYT--KQKYPEQPGRFAKLLLR 422
Query: 559 LPELRTLCTQGLQRIFYLKL 578
LP LR++ + L+ +F+ KL
Sbjct: 423 LPALRSIGLKCLEHLFFFKL 442
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 175 bits (444), Expect = 9e-44
Identities = 129/424 (30%), Positives = 196/424 (46%), Gaps = 38/424 (8%)
Query: 183 PGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQ 242
PG P + Q G + AGS QT P P + G G
Sbjct: 20 PGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGAPATPGTAGDKG-------- 71
Query: 243 LLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLAN 302
PP G C VCGD ++ +HYG TCEGCK FFKR+V++N Y C AN
Sbjct: 72 ------QGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRAN 125
Query: 303 KNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRL-PSKPKSPQEPSPPSPP 361
+NCP+D+ RN+CQYCR +KCL VGM +E V +RGR+ P++P Q P
Sbjct: 126 RNCPIDQHHRNQCQYCRLKKCLKVGMRREAV-------QRGRMPPTQPNPGQYALTNGDP 178
Query: 362 VS---LISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIR 418
++ +S + + + P TS S+ M ++ I+ +L +
Sbjct: 179 LNGHCYLSGYISLLLRAEPYPTSRYGSQC-------MQPNNIMGIENICELAARLLFSAV 231
Query: 419 GWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVE-GKLIFCNGVVLHRLQCVR 477
WA IP F DL DQ L + ELFVL A S P+ L+ G+ + R
Sbjct: 232 EWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR 291
Query: 478 --GFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIVNC 534
F + I E L+ +++D + +SC+ A+ + T + GL + +E LQ K
Sbjct: 292 VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCA 351
Query: 535 LKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLD 594
L+++V + N+P+ KLL +LP LRT+ + ++++F+++L P +I + L
Sbjct: 352 LEEYV--RSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLS 409
Query: 595 TLPF 598
F
Sbjct: 410 GSSF 413
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 172 bits (437), Expect = 6e-43
Identities = 132/410 (32%), Positives = 196/410 (47%), Gaps = 33/410 (8%)
Query: 205 EPAGSHHVVDGQTFAVPNPIR-KPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGL- 262
E GS Q VP P P + PG Q G AS T G P ++
Sbjct: 14 EVPGSQGSQASQAPPVPGPPPGAPHTPQTPG-QGGPASTPAQTAAGGQGGPGGPGSDKQQ 72
Query: 263 ------CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQ 316
C VCGD ++ +HYG TCEGCK FFKR+V++N Y C AN+NCP+D+ RN+CQ
Sbjct: 73 QQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQ 132
Query: 317 YCRFQKCLAVGMVKEVVRTDSLKGRRGRL-PSKPKSPQEPSPPSPPV---SLISALVRAH 372
YCR +KCL VGM +E V +RGR+ P++P Q P+ S +S +
Sbjct: 133 YCRLKKCLKVGMRREAV-------QRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLL 185
Query: 373 VDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPK 432
+ + P T SRF + M ++ I+ +L + WA IP F DL
Sbjct: 186 LRAEPYPT----SRFGSQ---CMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQI 238
Query: 433 ADQDLLFESAFLELFVLRLAYRSNPVE-GKLIFCNGVVLHRLQCVR--GFGEWIDSIVEF 489
DQ L + ELFVL A S P+ L+ G+ + R F + I E
Sbjct: 239 TDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQ 298
Query: 490 SSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNR 548
L+ +++D + +SC+ A+ + T + GL + VE LQ K L+++V + N+
Sbjct: 299 VEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYV--RSQYPNQ 356
Query: 549 PNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF 598
P KLL +LP LRT+ + ++++F+++L P +I + L F
Sbjct: 357 PTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSF 406
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 171 bits (432), Expect = 2e-42
Identities = 111/345 (32%), Positives = 176/345 (51%), Gaps = 14/345 (4%)
Query: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
LC VCGD A+ HYGV +CE CK FFKRT+Q + +Y C A+ C + KRRR CQ CRF
Sbjct: 78 LCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFT 137
Query: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSP---PSPPVSLISALVRAHVDSNPA 378
KCL VGM+KE VR D ++G R + +P+ P P P+ P+++ + N
Sbjct: 138 KCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNAL 197
Query: 379 MTSL---DYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQ 435
++ L + + A PD + DL + + WA+ IPGF+ L +DQ
Sbjct: 198 VSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQ 257
Query: 436 DLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQ 494
+ +S ++E+ VL +A RS P++ +L F +VL G GE ++++ LQ
Sbjct: 258 MSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQ 317
Query: 495 NMNIDISAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVT--FNNGGLNRPNY 551
+ ++ + + ALA+ ++ +++ + VE+L+ + L ++ GG
Sbjct: 318 ALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRR 377
Query: 552 LSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
+LL LP LR + L + +KLE VP + KLFL+ L
Sbjct: 378 AGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVP----MHKLFLEML 418
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 162 bits (410), Expect = 8e-40
Identities = 112/372 (30%), Positives = 174/372 (46%), Gaps = 32/372 (8%)
Query: 250 SPPSRGSPSNEGL---------CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL 300
SPP S + G C VCGD ++ +HYGV TCEGCK FFKR++++N Y C
Sbjct: 34 SPPGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCR 93
Query: 301 ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP 360
+N++C +D+ RN+CQYCR +KC VGM KE V+ RGR+P S SP
Sbjct: 94 SNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQ-------RGRIPHSLPGAVAASSGSP 146
Query: 361 PVSLISALVRA-HVDSNPAMTSLDYSRFQANPDYQMSG---------DDTQHIQQFYDLL 410
P S ++A+ + ++ L +A P +G I +L
Sbjct: 147 PGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELA 206
Query: 411 TGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVE-GKLIFCNGVV 469
+ WA P F +LP ADQ L ++ ELFVL A + P+ L+ G+
Sbjct: 207 ARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLH 266
Query: 470 LHRLQCVR--GFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEE 526
+ R F + + + E L + +D + + C+ A+A+ T + GL +P VE
Sbjct: 267 AAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVES 326
Query: 527 LQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPA 586
LQ K L ++V ++P +LL +LP LR + + ++F+++L P
Sbjct: 327 LQEKAQVALTEYVRAQYP--SQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIET 384
Query: 587 IIDKLFLDTLPF 598
+I + L F
Sbjct: 385 LIRDMLLSGSTF 396
>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
sapiens]
Length = 410
Score = 157 bits (398), Expect = 2e-38
Identities = 111/349 (31%), Positives = 169/349 (48%), Gaps = 29/349 (8%)
Query: 263 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKN--AKYVCLANKNCPVDKRRRNRCQYCRF 320
C VCGD A HY TCEGCKGFF+RT+QKN Y C + C +DK RN+CQ CRF
Sbjct: 53 CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRF 112
Query: 321 QKCLAVGMVKEVVRTDSLKGRRGRLPSKPKS-----------PQEPSPPSPPVSLISALV 369
+KC+AVGM ++V DS + + +L + + Q P P LI
Sbjct: 113 KKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIAT 172
Query: 370 RAHVDSNPAMTSLDYSRFQANPDYQMS-------GD--DTQHIQQFYDLLTGSMEIIRGW 420
AH +N + R D S GD D + +F ++T ++ + +
Sbjct: 173 EAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDF 232
Query: 421 AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVR-GF 479
A+K+P F++LP DQ +L + +E+ LR A R +P L + + R Q G
Sbjct: 233 AKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGL 292
Query: 480 GEWIDSIVEFSSNLQNMNIDISAFSCI-AALAMVTERHGLKEPKRVEELQNKIVNCLKDH 538
G D+I E +L N+D + + + A L M T+R GL ++E+ Q + + +
Sbjct: 293 GVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHY 352
Query: 539 VTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLE---DLVPP 584
V N+ N P++ KLL K+ +LR + R ++K+E +L PP
Sbjct: 353 V--NHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPP 399
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 155 bits (393), Expect = 8e-38
Identities = 114/384 (29%), Positives = 181/384 (47%), Gaps = 46/384 (11%)
Query: 238 GHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKY 297
G +L T + S CAVC D A+ HYGV +CEGCK FFKR++Q + Y
Sbjct: 160 GGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDY 219
Query: 298 VCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGR-------------RGR 344
+C A C +DK RR CQ CR +KC VGM+K +R D GR RG
Sbjct: 220 MCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGE 279
Query: 345 LPSKPKSPQEPSPPSP-----------PVSLIS-ALVRAHVDSNPAMTSLDYSRFQANPD 392
+ S PSP +SL + +V A +D+ P + +Y + +
Sbjct: 280 VGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSE 339
Query: 393 YQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLA 452
M G T +L + + WA+++PGF DL DQ L E A+LE+ ++ L
Sbjct: 340 ASMMGLLT-------NLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLV 392
Query: 453 YRSNPVEGKLIFCNGVVLHRLQ--CVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALA 510
+RS GKL+F ++L R Q CV G E D ++ SS + MN+ F C+ ++
Sbjct: 393 WRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII 452
Query: 511 MV---------TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY--LSKLLGKL 559
++ + L+E + + +KI + L H+ G + + L++LL L
Sbjct: 453 LLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 560 PELRTLCTQGLQRIFYLKLEDLVP 583
+R + +G++ ++ +K +++VP
Sbjct: 512 SHIRHMSNKGMEHLYSMKCKNVVP 535
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 155 bits (393), Expect = 8e-38
Identities = 114/384 (29%), Positives = 181/384 (47%), Gaps = 46/384 (11%)
Query: 238 GHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKY 297
G +L T + S CAVC D A+ HYGV +CEGCK FFKR++Q + Y
Sbjct: 160 GGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDY 219
Query: 298 VCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGR-------------RGR 344
+C A C +DK RR CQ CR +KC VGM+K +R D GR RG
Sbjct: 220 MCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGE 279
Query: 345 LPSKPKSPQEPSPPSP-----------PVSLIS-ALVRAHVDSNPAMTSLDYSRFQANPD 392
+ S PSP +SL + +V A +D+ P + +Y + +
Sbjct: 280 VGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSE 339
Query: 393 YQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLA 452
M G T +L + + WA+++PGF DL DQ L E A+LE+ ++ L
Sbjct: 340 ASMMGLLT-------NLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLV 392
Query: 453 YRSNPVEGKLIFCNGVVLHRLQ--CVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALA 510
+RS GKL+F ++L R Q CV G E D ++ SS + MN+ F C+ ++
Sbjct: 393 WRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII 452
Query: 511 MV---------TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY--LSKLLGKL 559
++ + L+E + + +KI + L H+ G + + L++LL L
Sbjct: 453 LLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 560 PELRTLCTQGLQRIFYLKLEDLVP 583
+R + +G++ ++ +K +++VP
Sbjct: 512 SHIRHMSNKGMEHLYSMKCKNVVP 535
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 155 bits (393), Expect = 8e-38
Identities = 114/384 (29%), Positives = 181/384 (47%), Gaps = 46/384 (11%)
Query: 238 GHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKY 297
G +L T + S CAVC D A+ HYGV +CEGCK FFKR++Q + Y
Sbjct: 160 GGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDY 219
Query: 298 VCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGR-------------RGR 344
+C A C +DK RR CQ CR +KC VGM+K +R D GR RG
Sbjct: 220 MCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGE 279
Query: 345 LPSKPKSPQEPSPPSP-----------PVSLIS-ALVRAHVDSNPAMTSLDYSRFQANPD 392
+ S PSP +SL + +V A +D+ P + +Y + +
Sbjct: 280 VGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSE 339
Query: 393 YQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLA 452
M G T +L + + WA+++PGF DL DQ L E A+LE+ ++ L
Sbjct: 340 ASMMGLLT-------NLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLV 392
Query: 453 YRSNPVEGKLIFCNGVVLHRLQ--CVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALA 510
+RS GKL+F ++L R Q CV G E D ++ SS + MN+ F C+ ++
Sbjct: 393 WRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII 452
Query: 511 MV---------TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY--LSKLLGKL 559
++ + L+E + + +KI + L H+ G + + L++LL L
Sbjct: 453 LLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 560 PELRTLCTQGLQRIFYLKLEDLVP 583
+R + +G++ ++ +K +++VP
Sbjct: 512 SHIRHMSNKGMEHLYSMKCKNVVP 535
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 155 bits (393), Expect = 8e-38
Identities = 114/384 (29%), Positives = 181/384 (47%), Gaps = 46/384 (11%)
Query: 238 GHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKY 297
G +L T + S CAVC D A+ HYGV +CEGCK FFKR++Q + Y
Sbjct: 160 GGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDY 219
Query: 298 VCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGR-------------RGR 344
+C A C +DK RR CQ CR +KC VGM+K +R D GR RG
Sbjct: 220 MCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGE 279
Query: 345 LPSKPKSPQEPSPPSP-----------PVSLIS-ALVRAHVDSNPAMTSLDYSRFQANPD 392
+ S PSP +SL + +V A +D+ P + +Y + +
Sbjct: 280 VGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSE 339
Query: 393 YQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLA 452
M G T +L + + WA+++PGF DL DQ L E A+LE+ ++ L
Sbjct: 340 ASMMGLLT-------NLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLV 392
Query: 453 YRSNPVEGKLIFCNGVVLHRLQ--CVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALA 510
+RS GKL+F ++L R Q CV G E D ++ SS + MN+ F C+ ++
Sbjct: 393 WRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII 452
Query: 511 MV---------TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY--LSKLLGKL 559
++ + L+E + + +KI + L H+ G + + L++LL L
Sbjct: 453 LLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLIL 511
Query: 560 PELRTLCTQGLQRIFYLKLEDLVP 583
+R + +G++ ++ +K +++VP
Sbjct: 512 SHIRHMSNKGMEHLYSMKCKNVVP 535
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,484,737
Number of Sequences: 37866
Number of extensions: 1452456
Number of successful extensions: 7926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 7369
Number of HSP's gapped (non-prelim): 504
length of query: 598
length of database: 18,247,518
effective HSP length: 108
effective length of query: 490
effective length of database: 14,157,990
effective search space: 6937415100
effective search space used: 6937415100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.