Guide to the Human Genome
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Search of human proteins with 5453680

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453680 neural precursor cell expressed, developmentally
down-regulated 9 isoform 1 [Homo sapiens]
         (834 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453680 neural precursor cell expressed, developmentally down...  1702   0.0  
gi|215422375 neural precursor cell expressed, developmentally do...  1694   0.0  
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]   516   e-146
gi|78486553 neural precursor cell expressed, developmentally dow...   322   1e-87
gi|55769585 HEF-like protein [Homo sapiens]                           266   8e-71
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r...   137   3e-32
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r...   134   3e-31
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r...   134   3e-31
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r...   134   3e-31
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s...   117   3e-26
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...   117   3e-26
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                52   3e-06
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                52   3e-06
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    49   3e-05
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H...    49   3e-05
gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Ho...    49   3e-05
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]                       47   7e-05
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s...    47   7e-05
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    47   1e-04
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    47   1e-04
gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]             45   3e-04
gi|27544941 myosin IF [Homo sapiens]                                   45   4e-04
gi|20149528 proline-serine-threonine phosphatase interacting pro...    45   4e-04
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    44   5e-04
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    44   5e-04
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    44   5e-04
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    44   5e-04
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    44   5e-04
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]    44   6e-04
gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    44   8e-04

>gi|5453680 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 1 [Homo sapiens]
          Length = 834

 Score = 1702 bits (4408), Expect = 0.0
 Identities = 834/834 (100%), Positives = 834/834 (100%)

Query: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV
Sbjct: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60

Query: 61  KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120
           KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV
Sbjct: 61  KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120

Query: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIP 180
           PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIP
Sbjct: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIP 180

Query: 181 PSHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKD 240
           PSHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKD
Sbjct: 181 PSHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKD 240

Query: 241 YDFPPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPN 300
           YDFPPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPN
Sbjct: 241 YDFPPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPN 300

Query: 301 HPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRD 360
           HPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRD
Sbjct: 301 HPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRD 360

Query: 361 LVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQAL 420
           LVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQAL
Sbjct: 361 LVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQAL 420

Query: 421 EMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELI 480
           EMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELI
Sbjct: 421 EMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELI 480

Query: 481 LHNKMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPD 540
           LHNKMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPD
Sbjct: 481 LHNKMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPD 540

Query: 541 DAKQLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHN 600
           DAKQLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHN
Sbjct: 541 DAKQLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHN 600

Query: 601 KALPPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQ 660
           KALPPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQ
Sbjct: 601 KALPPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQ 660

Query: 661 LEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFI 720
           LEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFI
Sbjct: 661 LEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFI 720

Query: 721 SLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSS 780
           SLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSS
Sbjct: 721 SLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSS 780

Query: 781 NQLCEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834
           NQLCEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF
Sbjct: 781 NQLCEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834


>gi|215422375 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 3 [Homo sapiens]
          Length = 834

 Score = 1694 bits (4388), Expect = 0.0
 Identities = 830/831 (99%), Positives = 831/831 (100%)

Query: 4   KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           +NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL
Sbjct: 4   RNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63

Query: 64  IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG 123
           IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG
Sbjct: 64  IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG 123

Query: 124 HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSH 183
           HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSH
Sbjct: 124 HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSH 183

Query: 184 TTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKDYDF 243
           TTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKDYDF
Sbjct: 184 TTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKDYDF 243

Query: 244 PPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP 303
           PPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP
Sbjct: 244 PPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP 303

Query: 304 PQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRDLVD 363
           PQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRDLVD
Sbjct: 304 PQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRDLVD 363

Query: 364 GINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMG 423
           GINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMG
Sbjct: 364 GINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMG 423

Query: 424 VSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHN 483
           VSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHN
Sbjct: 424 VSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHN 483

Query: 484 KMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAK 543
           KMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAK
Sbjct: 484 KMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAK 543

Query: 544 QLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKAL 603
           QLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKAL
Sbjct: 544 QLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKAL 603

Query: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
           PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH
Sbjct: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663

Query: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
           HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL
Sbjct: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723

Query: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
           NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL
Sbjct: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783

Query: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834
           CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF
Sbjct: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834


>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
          Length = 870

 Score =  516 bits (1328), Expect = e-146
 Identities = 372/940 (39%), Positives = 491/940 (52%), Gaps = 180/940 (19%)

Query: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           M + N++A+ALYDNV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGNR+
Sbjct: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60

Query: 61  KLLIG--------PMQETASSHEQPASGL-------------MQQTF------------- 86
           K+L+G        P     ++  QP  GL             +  T+             
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 87  --GQQKLYQVPNPQA-----------------------APRDTIYQVPPSYQN--QGIYQ 119
              QQ LYQVP P                         +P   +YQVPP      Q IYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180

Query: 120 VPTGHGTQEQEVYQVPPSVQ-RSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQ----- 173
           VP   G    ++YQVPPS+  RS  GT  P    KV+ P R G GYVYE     Q     
Sbjct: 181 VPPSAG-MGHDIYQVPPSMDTRSWEGTKPP---AKVVVPTRVGQGYVYEAAQPEQDEYDI 236

Query: 174 ---------KDVYDIPP------SHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPP 218
                    +D+YD+PP      S   Q VYD PP + KGP    P+ E     VYD+PP
Sbjct: 237 PRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLE-----VYDVPP 291

Query: 219 T--KG--------VYAIPPSACRDEAG---LREKDYDFPPPMRQAGRPD-LRPEGVYDIP 264
           +  KG        VY +PPS  +D      LRE+ YD PP   +A   D  R   V   P
Sbjct: 292 SVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAP 351

Query: 265 PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQ 324
           P  + PA +D++     D+P    P A     + P    P  G         YDVPR  +
Sbjct: 352 PPDSPPA-EDVY-----DVP----PPAPDLYDVPPGLRRPGPGT-------LYDVPR--E 392

Query: 325 FLEPPAETSEKANPQERD-GVYDVPLHNPPDAKGSRDLVDGINRLSFSSTGSTRSNMSTS 383
            + PP    E A+    D GVY VP   PP     R+      RLS SSTGSTRS+ S S
Sbjct: 393 RVLPP----EVADGGVVDSGVYAVP---PP---AEREAPAEGKRLSASSTGSTRSSQSAS 442

Query: 384 STSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALV-----TTDWRCY 438
           S         A P ++    L+ + A+E L RLQQ +   V+ L+ L      T  WR  
Sbjct: 443 SLEV------AGPGREP---LELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSP 493

Query: 439 GY-MERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQ 497
               E  + +++ AV  V+  + E L F + AV NAA   +  LH K+ R+LQ++ED HQ
Sbjct: 494 SEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQ 553

Query: 498 ILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALF 557
            L      L+                  +DLDR V  ++ VP+DAKQL + ++ NA  LF
Sbjct: 554 TLVAHGQALDAGRGGSGATL--------EDLDRLVACSRAVPEDAKQLASFLHGNASLLF 605

Query: 558 RPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPG--DHKAQAHNKALP--PGLSKEQAP 613
           R    +     GPE              G  LHP   D  +   ++ LP  P  + + +P
Sbjct: 606 RRTKATAP---GPEG-------------GGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSP 649

Query: 614 DCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEHHQLSQFQLLE 673
           D    + SE  WM+DYDYVHLQGKEEFE+ QKELLEK +I +Q K QLE  QL QF+ LE
Sbjct: 650 D-GQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLE 708

Query: 674 QEITKPVENDISKWKPSQSL-PTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSC 732
           QE+++P+++D++ W P+Q L P    G+   DRQLL FY +QCE +  +L NA+DA F+ 
Sbjct: 709 QEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTA 768

Query: 733 VSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVM 792
           V++ QPP+IFVAHSKFVILSAHKLVFIGDTL+RQ  A D+R++V + SN LC+ L+ IV 
Sbjct: 769 VATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVA 828

Query: 793 ATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
            TK AAL YPS +A Q+MV +V +L  + Q F+R L ++A
Sbjct: 829 TTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLA 868


>gi|78486553 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 2 [Homo sapiens]
          Length = 174

 Score =  322 bits (824), Expect = 1e-87
 Identities = 154/154 (100%), Positives = 154/154 (100%)

Query: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV
Sbjct: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60

Query: 61  KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120
           KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV
Sbjct: 61  KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120

Query: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKV 154
           PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKV
Sbjct: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKV 154


>gi|55769585 HEF-like protein [Homo sapiens]
          Length = 786

 Score =  266 bits (679), Expect = 8e-71
 Identities = 248/873 (28%), Positives = 390/873 (44%), Gaps = 147/873 (16%)

Query: 4   KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           K L+ARALYDN P+C++ELAF +GDILT++EQ+    EGWW C LHGRQG+ P NR+++L
Sbjct: 12  KALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL 71

Query: 64  IGPMQETASSHEQP--ASGLMQQTFGQQKLYQVPN-PQAAPRDTIYQVPPSYQNQGIYQV 120
                E A+    P    GL +     ++ YQVP  P+      +Y+   S+      Q 
Sbjct: 72  ----TEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGP--QP 125

Query: 121 PTGHGTQEQEVYQV--PPSVQRSIGGTSGPHVGKKVIT---PVR----TGHGYVYEYPSR 171
           PT       +VY+   PP+  R I   +     + ++T   PVR    T    VY+ P++
Sbjct: 126 PTA------QVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQ 179

Query: 172 Y----------QKDVYDIPPSHTTQGVYDIPPSSAKG---PVFSVPV----------GEI 208
           +          ++ +YDIP S    G++  P S A G   P+ SV               
Sbjct: 180 HRGPVVLKEPEKQQLYDIPASPKKAGLHP-PDSQASGQGVPLISVTTLRRGGYSTLPNPQ 238

Query: 209 KPQGVYDIPPTKGVYAI---PPSACRDEA---GLREKDYDFPPPMRQAGRPDLRPEGVYD 262
           K + +YD P + G  ++   P ++  +E+    L      F  P     R  L P+   +
Sbjct: 239 KSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSR-SLTPQLNNN 297

Query: 263 IPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQN---DAYDV 319
           +P    K         Y   +P    P+    + +S   P   L   V  QN   + YD+
Sbjct: 298 VP--MQKKLSLPEIPSYGFLVPRGTFPL---DEDVSYKVPSSFLIPRVEQQNTKPNIYDI 352

Query: 320 PRGVQFLEPPAETSEKANPQERDGVYDVPLHNPP-DAKGSRDLVDGINRLSFSSTGSTRS 378
           P+    +    +  EKA     +       HN    ++ +       +RLS SS+ S  S
Sbjct: 353 PKATSSVSQAGKELEKAKEVSENSAG----HNSSWFSRRTTSPSPEPDRLSGSSSDSRAS 408

Query: 379 NMST-SSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALVTTDWRC 437
            +S+ S+TS+ +SS S+S    K L LD D A E +  LQ  +   V+ LM  V+  WR 
Sbjct: 409 IVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRF 468

Query: 438 YGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQ 497
             Y+E +I+ I  + D +E  ++E+L F +G    A  L +  L N+++ ++Q + +S++
Sbjct: 469 RDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYR 528

Query: 498 ILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALF 557
           IL +T   L+  +W L +L  +  QN  DDL+RFVMVA+ +P+D K+  + +  N   LF
Sbjct: 529 ILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLF 588

Query: 558 RPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKALPPGLSKEQAPDCSS 617
           +        K     +  + E+       + + P   + ++H K+ P   S +Q  D  S
Sbjct: 589 KRNCE----KEETVQLTPNAEF----KCEKYIQPPQRETESHQKSTP---STKQREDEHS 637

Query: 618 SDGSERSWMDDYDYVHLQGKEEFERQQKELLEKE--NIMKQNKMQLEHHQLSQFQLLEQE 675
           S                           ELL+K   NI  QN   L              
Sbjct: 638 S---------------------------ELLKKNRANICGQNPGPL-------------- 656

Query: 676 ITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSS 735
           I +P      + KP  S                    + C  +F +L  AI A    +SS
Sbjct: 657 IPQPSSQQTPERKPRLS--------------------EHCRLYFGALFKAISAFHGSLSS 696

Query: 736 AQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVMATK 795
           +QP  I +  SK VI+   KLV   DTL  +   +D+RN+++  S+ LC  LK + +ATK
Sbjct: 697 SQPAEI-ITQSKLVIMVGQKLV---DTLCMETQERDVRNEILRGSSHLCSLLKDVALATK 752

Query: 796 MAALHYPSTTALQEMVHQVTDLSRNAQLFKRSL 828
            A L YPS  AL  +  +   L ++ + F+ +L
Sbjct: 753 NAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTL 785


>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 353

 Score =  137 bits (346), Expect = 3e-32
 Identities = 112/329 (34%), Positives = 152/329 (46%), Gaps = 38/329 (11%)

Query: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           M + N++A+ALYDNV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGI+PGN +
Sbjct: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60

Query: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS 170
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH          T    V   P 
Sbjct: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH---HPFPSPATDLYQVSPGPG 172

Query: 171 RYQKDVYDIPPS-HTTQGVYDIPPS-------SAKGPVFSVPVGE---IKPQGVYDIPPT 219
              +D+Y +PPS      +Y +P S         K P     V     + P+G+   P  
Sbjct: 173 GPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGL-GSPSF 231

Query: 220 KGVYAIPPSA----CRDEAGLREKDYDFPPPMRQAGRPDL--RPEGVYDIPPTCTKPAGK 273
             +Y  P  A    CR   G   + + + P + +  +P L   P      P  C+     
Sbjct: 232 LLIYLSPAPARGEPCRALTGHLSQRH-WAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTL 290

Query: 274 DLHV-KYNCDIPGAAEPVARRHQSLSPNH 301
            +HV K     P A+ PV  R    S  H
Sbjct: 291 RIHVEKEAVTTPEASSPVRSRGTPRSSRH 319


>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 232

 Score =  134 bits (338), Expect = 3e-31
 Identities = 86/217 (39%), Positives = 116/217 (53%), Gaps = 35/217 (16%)

Query: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           M + N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS 170
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS
Sbjct: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPS 159

Query: 171 RYQKDVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
               D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 160 P-ATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 33/153 (21%), Positives = 58/153 (37%), Gaps = 29/153 (18%)

Query: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141

Query: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPTCTKPAGKDLHVKYNCDI 283
           +        +   + FP P     +    P G    +Y +PP+     G D++      +
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSA--GMGHDIY-----QV 194

Query: 284 PGAAEPVARRHQSLSP---NHPPPQLGQSVGSQ 313
           P + +   R  +   P    +P P +G + G Q
Sbjct: 195 PSSMD--TRSWEGTKPPAKANPSPLMGHARGQQ 225


>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 224

 Score =  134 bits (338), Expect = 3e-31
 Identities = 86/217 (39%), Positives = 116/217 (53%), Gaps = 35/217 (16%)

Query: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           M + N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS 170
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS
Sbjct: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPS 159

Query: 171 RYQKDVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
               D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 160 P-ATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 17/103 (16%)

Query: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141

Query: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPT 266
           +        +   + FP P     +    P G    +Y +PP+
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPS 184


>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 368

 Score =  134 bits (338), Expect = 3e-31
 Identities = 86/217 (39%), Positives = 116/217 (53%), Gaps = 35/217 (16%)

Query: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           M + N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS 170
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS
Sbjct: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPS 159

Query: 171 RYQKDVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
               D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 160 P-ATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 22/145 (15%)

Query: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141

Query: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPTCTKPAGKDLH-VKYNCD 282
           +        +   + FP P     +    P G    +Y +PP+     G D++ V  + D
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSA--GMGHDIYQVPSSMD 199

Query: 283 IPG--AAEPVARRHQSLSPNHPPPQ 305
                  +P A+     SP   PP+
Sbjct: 200 TRSWEGTKPPAKCASVSSPRCLPPR 224


>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
           sapiens]
          Length = 468

 Score =  117 bits (294), Expect = 3e-26
 Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)

Query: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
           P G   E  P    ++       ++YDYVHL+G ++                Q     + 
Sbjct: 263 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 307

Query: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
                 +L E+ +  P E       P + L      VS  D QLL FY  QC++H+ +L 
Sbjct: 308 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 358

Query: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
            A+ AL S   + QPPR+FV HSK V+++AH+LVF+GDTL R   +  +R +V  +   L
Sbjct: 359 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 418

Query: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
            + L+  V+A K AAL YPS+ A+QEMV  VT+L+  A  F   L  +A
Sbjct: 419 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 467



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 69/269 (25%), Positives = 91/269 (33%), Gaps = 73/269 (27%)

Query: 131 VYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS---------RYQKDVYDIPP 181
           VY VPP  +     TSGP  G     P       +Y+ P          R   +VYD+PP
Sbjct: 7   VYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP 59

Query: 182 SHT---TQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP--------------- 217
           +     + G YD P S      FS P+  + PQ        YD+P               
Sbjct: 60  TALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEW 113

Query: 218 -----PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDIP------PT 266
                P   +YA P +  R  A L    Y+ P  +   G      EG+YD+P      P 
Sbjct: 114 EGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYDVPLLGPEAPP 171

Query: 267 CTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQNDAYDVPRGVQ 324
             +P G       + D    A+ +AR   S  P H P  P           A  VP    
Sbjct: 172 SPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPLPALPVPEA-- 222

Query: 325 FLEPPAETSEKANPQERDGVYDVPLHNPP 353
              P         P  +  + D PL  PP
Sbjct: 223 ---PSPSPVPSPAPGRKGSIQDRPLPPPP 248


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score =  117 bits (294), Expect = 3e-26
 Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)

Query: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
           P G   E  P    ++       ++YDYVHL+G ++                Q     + 
Sbjct: 356 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 400

Query: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
                 +L E+ +  P E       P + L      VS  D QLL FY  QC++H+ +L 
Sbjct: 401 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 451

Query: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
            A+ AL S   + QPPR+FV HSK V+++AH+LVF+GDTL R   +  +R +V  +   L
Sbjct: 452 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 511

Query: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
            + L+  V+A K AAL YPS+ A+QEMV  VT+L+  A  F   L  +A
Sbjct: 512 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 560



 Score =  116 bits (291), Expect = 8e-26
 Identities = 119/395 (30%), Positives = 156/395 (39%), Gaps = 110/395 (27%)

Query: 7   MARALYDNVPECAEELAFRKGDILTVIE-QNTGGLEGWWLCSLHGRQGIVPGNRVKLL-I 64
           +ARALYDN  E  +EL+FR+GD+L V++ +  GGL+GW LCSLHG+QGIVP NRVKLL  
Sbjct: 9   LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPA 68

Query: 65  GPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTGH 124
           GP  + + S   PA              Q  +P  AP                      H
Sbjct: 69  GPAPKPSLSPASPA--------------QPGSPYPAP---------------------DH 93

Query: 125 GTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYP---------SRYQKD 175
             ++QEVY VPP  +     TSGP  G     P       +Y+ P          R   +
Sbjct: 94  SNEDQEVYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPRDALE 146

Query: 176 VYDIPPSH---TTQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP--------- 217
           VYD+PP+     + G YD P S      FS P+  + PQ        YD+P         
Sbjct: 147 VYDVPPTALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAEL 200

Query: 218 -----------PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDIP-- 264
                      P   +YA P +  R  A L    Y+ P  +   G      EG+YD+P  
Sbjct: 201 EPDLEWEGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYDVPLL 258

Query: 265 ----PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQNDAYD 318
               P   +P G       + D    A+ +AR   S  P H P  P           A  
Sbjct: 259 GPEAPPSPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPLPALP 311

Query: 319 VPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPP 353
           VP       P         P  +  + D PL  PP
Sbjct: 312 VPEA-----PSPSPVPSPAPGRKGSIQDRPLPPPP 341


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 19/104 (18%)

Query: 2    KYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVK 61
            K + L A+ALY    +    L F K D++TV+EQ     + WW   + G++G  P + VK
Sbjct: 912  KVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQ----DMWWFGEVQGQKGWFPKSYVK 967

Query: 62   LLIGPMQETAS----SHEQPASGLMQQTFGQQKLYQVPNPQAAP 101
            L+ GP++++ S    S E PAS           L +V +P A P
Sbjct: 968  LISGPIRKSTSMDSGSSESPAS-----------LKRVASPAAKP 1000



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 11   LYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            +YD   +  +ELAF KG I+ V+ +       WW   ++G+ G+ P N VKL
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKED---PDWWKGEVNGQVGLFPSNYVKL 1211


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 19/104 (18%)

Query: 2    KYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVK 61
            K + L A+ALY    +    L F K D++TV+EQ     + WW   + G++G  P + VK
Sbjct: 912  KVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQ----DMWWFGEVQGQKGWFPKSYVK 967

Query: 62   LLIGPMQETAS----SHEQPASGLMQQTFGQQKLYQVPNPQAAP 101
            L+ GP++++ S    S E PAS           L +V +P A P
Sbjct: 968  LISGPIRKSTSMDSGSSESPAS-----------LKRVASPAAKP 1000



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 5/64 (7%)

Query: 11   LYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL--IGPMQ 68
            +YD   +  +ELAF KG I+ V+ +       WW   ++G+ G+ P N VKL   + P Q
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKED---PDWWKGEVNGQVGLFPSNYVKLTTDMDPSQ 1219

Query: 69   ETAS 72
            +  S
Sbjct: 1220 QWCS 1223


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 1/52 (1%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           R L+D  PE  +ELA R+GD++ V+ + T   +GWW     GR+G+ P N V
Sbjct: 187 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFV 237



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 22/100 (22%)

Query: 16  PECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL-IGPMQETASSH 74
           PE A+EL  + G+I+ +I++     +GWWL   +G+ G  P N V+LL  GP   +  + 
Sbjct: 96  PEQADELKLQAGEIVEMIKEIE---DGWWLGKKNGQLGAFPSNFVELLDSGP--PSLGNP 150

Query: 75  EQPASGLMQQTFGQQKLYQVPNPQAAPR--DTIYQVPPSY 112
           + P+                P PQ  P+     Y  PP Y
Sbjct: 151 DMPSVS--------------PGPQRPPKLSSLAYDSPPDY 176


>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
           sapiens]
          Length = 645

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 1/52 (1%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           R L+D  PE  +ELA R+GD++ V+ + T   +GWW     GR+G+ P N V
Sbjct: 76  RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFV 126



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 19/75 (25%)

Query: 41  EGWWLCSLHGRQGIVPGNRVKLL-IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQA 99
           +GWWL   +G+ G  P N V+LL  GP   +  + + P+                P PQ 
Sbjct: 7   DGWWLGKKNGQLGAFPSNFVELLDSGP--PSLGNPDMPSVS--------------PGPQR 50

Query: 100 APR--DTIYQVPPSY 112
            P+     Y  PP Y
Sbjct: 51  PPKLSSLAYDSPPDY 65


>gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Homo
           sapiens]
          Length = 847

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 31/76 (40%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 3   YKNLMARALYDNVPECAEELAFRKGDILTVIEQNT--GGLEGWWLCSLHGRQGIVPGNRV 60
           Y N +  AL+D  P   +ELA RKGD + V+ ++    G EGWW   + G+ GI P N V
Sbjct: 41  YANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYV 100

Query: 61  KLLIGPMQ-ETASSHE 75
               GP   E AS  E
Sbjct: 101 SRGGGPPPCEVASFQE 116


>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
          Length = 352

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 25/56 (44%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           RALYD  PE   EL F++GDI+T+  Q     E W+   LHG  G  P N V++L+
Sbjct: 296 RALYDFEPENEGELGFKEGDIITLTNQID---ENWYEGMLHGHSGFFPINYVEILV 348


>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
           sapiens]
          Length = 486

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 6   LMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           + A ALYD   E ++EL+F   D++T IE      EGWW    HG  G+ P N VKLL
Sbjct: 431 ISAVALYDYQGEGSDELSFDPDDVITDIEMVD---EGWWRGRCHGHFGLFPANYVKLL 485


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 20/49 (40%), Positives = 32/49 (65%)

Query: 10  ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGN 58
           AL+D   E  +EL+FR+G+ +TV+ ++      WW  +LHG++G VP N
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRN 813



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 23/84 (27%), Positives = 30/84 (35%)

Query: 293 RHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNP 352
           R+ S S   P    G    +  D  D P G     P        +P+ R      PL+  
Sbjct: 69  RYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQ 128

Query: 353 PDAKGSRDLVDGINRLSFSSTGST 376
           PDA GS D        +F   GS+
Sbjct: 129 PDAYGSLDRATSPRPRAFDGAGSS 152


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 20/49 (40%), Positives = 32/49 (65%)

Query: 10  ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGN 58
           AL+D   E  +EL+FR+G+ +TV+ ++      WW  +LHG++G VP N
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRN 813



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 23/84 (27%), Positives = 30/84 (35%)

Query: 293 RHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNP 352
           R+ S S   P    G    +  D  D P G     P        +P+ R      PL+  
Sbjct: 69  RYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQ 128

Query: 353 PDAKGSRDLVDGINRLSFSSTGST 376
           PDA GS D        +F   GS+
Sbjct: 129 PDAYGSLDRATSPRPRAFDGAGSS 152


>gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]
          Length = 403

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/61 (39%), Positives = 39/61 (63%), Gaps = 2/61 (3%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTV-IEQNTGGLEGWWLCSLHGR-QGIVPGNRVKL 62
           +++ARA YD      EE++FR GD+L + +++    + GW L SL G+  G++P N VK+
Sbjct: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333

Query: 63  L 63
           L
Sbjct: 334 L 334


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 3/53 (5%)

Query: 9    RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVK 61
            RALY  V +  +EL+F   +++ ++ ++  G   WW   LHG++G+ PGN V+
Sbjct: 1047 RALYQYVGQDVDELSFNVNEVIEILMEDPSG---WWKGRLHGQEGLFPGNYVE 1096


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 3/55 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           RALYD   +  +EL    GDIL VI +   G +GWW    +G++G VPG+ ++ L
Sbjct: 365 RALYDYTAQNPDELDLSAGDILEVILE---GEDGWWTVERNGQRGFVPGSYLEKL 416


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 12  YDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETA 71
           +  +P+  +EL  + GDI+ V+ +     EGWW   L+G+ G+ P N +K L G   E  
Sbjct: 70  FSYLPQNDDELELKVGDIIEVVGEVE---EGWWEGVLNGKTGMFPSNFIKELSGESDELG 126

Query: 72  -SSHEQPASGLMQQTFGQQ 89
            S  EQ +   +++T G +
Sbjct: 127 ISQDEQLSKSSLRETTGSE 145



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 1/58 (1%)

Query: 20  EELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETASSHEQP 77
           +EL  ++GDI+T+I ++   + GWW   L+GR+G+ P N VKLL    ++  +  ++P
Sbjct: 247 DELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFEKEGNRPKKP 303


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 12  YDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETA 71
           +  +P+  +EL  + GDI+ V+ +     EGWW   L+G+ G+ P N +K L G   E  
Sbjct: 107 FSYLPQNDDELELKVGDIIEVVGEVE---EGWWEGVLNGKTGMFPSNFIKELSGESDELG 163

Query: 72  -SSHEQPASGLMQQTFGQQ 89
            S  EQ +   +++T G +
Sbjct: 164 ISQDEQLSKSSLRETTGSE 182



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 1/58 (1%)

Query: 20  EELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETASSHEQP 77
           +EL  ++GDI+T+I ++   + GWW   L+GR+G+ P N VKLL    ++  +  ++P
Sbjct: 284 DELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFEKEGNRPKKP 340



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 3/80 (3%)

Query: 12 YDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETA 71
          +D   +  +EL    G+I+T I +  GG   WW   ++GR+G+ P N V+ +   M++  
Sbjct: 8  FDYQAQHDDELTISVGEIITNIRKEDGG---WWEGQINGRRGLFPDNFVREIKKEMKKDP 64

Query: 72 SSHEQPASGLMQQTFGQQKL 91
           +++ P   L +   G   L
Sbjct: 65 LTNKAPEKPLHEVPSGNSLL 84


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 13/110 (11%)

Query: 4   KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           +NL A+AL     +    L F K DI+TV+EQ     E WW   +HG +G  P + VK++
Sbjct: 872 ENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQ----ENWWFGEVHGGRGWFPKSYVKII 927

Query: 64  IG-------PMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIY 106
            G       P    A+ +++P S     + G++ +   P     P D  +
Sbjct: 928 PGSEVKREEPEALYAAVNKKPTSA--AYSVGEEYIALYPYSSVEPGDLTF 975



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            A+YD      +EL+F KG ++ V+ ++      WW   ++G  G+ P N VK+
Sbjct: 1107 AMYDYAANNEDELSFSKGQLINVMNKDD---PDWWQGEINGVTGLFPSNYVKM 1156



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQ 68
           RALY       +E++F  GDI+ V ++ T G  GW   S  G  G  P N V+ +     
Sbjct: 736 RALYPFEARNHDEMSFNSGDIIQV-DEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSEN 794

Query: 69  ETASSHEQPASGLMQQT 85
           E A S   P   L+  T
Sbjct: 795 EKAVS---PKKALLPPT 808



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)

Query: 19   AEELAFRKGDILTVIEQNTGGLEGWWLCSLHGR-----QGIVPGNRVKLLIGPMQETASS 73
            +E+L+   G ++ ++++NT    GWW   L  R     +G  P + VKLL GP  E A+ 
Sbjct: 1042 SEQLSLAPGQLILILKKNT---SGWWQGELQARGKKRQKGWFPASHVKLL-GPSSERATP 1097

Query: 74   HEQP 77
               P
Sbjct: 1098 AFHP 1101


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 13/110 (11%)

Query: 4    KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
            +NL A+AL     +    L F K DI+TV+EQ     E WW   +HG +G  P + VK++
Sbjct: 899  ENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQ----ENWWFGEVHGGRGWFPKSYVKII 954

Query: 64   IG-------PMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIY 106
             G       P    A+ +++P S     + G++ +   P     P D  +
Sbjct: 955  PGSEVKREEPEALYAAVNKKPTSA--AYSVGEEYIALYPYSSVEPGDLTF 1002



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            A+YD      +EL+F KG ++ V+ ++      WW   ++G  G+ P N VK+
Sbjct: 1134 AMYDYAANNEDELSFSKGQLINVMNKDD---PDWWQGEINGVTGLFPSNYVKM 1183



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQ 68
           RALY       +E++F  GDI+ V ++ T G  GW   S  G  G  P N V+ +     
Sbjct: 763 RALYPFEARNHDEMSFNSGDIIQV-DEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSEN 821

Query: 69  ETASSHEQPASGLMQQT 85
           E A S   P   L+  T
Sbjct: 822 EKAVS---PKKALLPPT 835



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)

Query: 19   AEELAFRKGDILTVIEQNTGGLEGWWLCSLHGR-----QGIVPGNRVKLLIGPMQETASS 73
            +E+L+   G ++ ++++NT    GWW   L  R     +G  P + VKLL GP  E A+ 
Sbjct: 1069 SEQLSLAPGQLILILKKNT---SGWWQGELQARGKKRQKGWFPASHVKLL-GPSSERATP 1124

Query: 74   HEQP 77
               P
Sbjct: 1125 AFHP 1128


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 13/110 (11%)

Query: 4    KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
            +NL A+AL     +    L F K DI+TV+EQ     E WW   +HG +G  P + VK++
Sbjct: 899  ENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQ----ENWWFGEVHGGRGWFPKSYVKII 954

Query: 64   IG-------PMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIY 106
             G       P    A+ +++P S     + G++ +   P     P D  +
Sbjct: 955  PGSEVKREEPEALYAAVNKKPTSA--AYSVGEEYIALYPYSSVEPGDLTF 1002



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            A+YD      +EL+F KG ++ V+ ++      WW   ++G  G+ P N VK+
Sbjct: 1134 AMYDYAANNEDELSFSKGQLINVMNKDD---PDWWQGEINGVTGLFPSNYVKM 1183



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQ 68
           RALY       +E++F  GDI+ V ++ T G  GW   S  G  G  P N V+ +     
Sbjct: 763 RALYPFEARNHDEMSFNSGDIIQV-DEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSEN 821

Query: 69  ETASSHEQPASGLMQQT 85
           E A S   P   L+  T
Sbjct: 822 EKAVS---PKKALLPPT 835



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)

Query: 19   AEELAFRKGDILTVIEQNTGGLEGWWLCSLHGR-----QGIVPGNRVKLLIGPMQETASS 73
            +E+L+   G ++ ++++NT    GWW   L  R     +G  P + VKLL GP  E A+ 
Sbjct: 1069 SEQLSLAPGQLILILKKNT---SGWWQGELQARGKKRQKGWFPASHVKLL-GPSSERATP 1124

Query: 74   HEQP 77
               P
Sbjct: 1125 AFHP 1128


>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
          Length = 1090

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 2/66 (3%)

Query: 7    MARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL--I 64
            +A AL+D   + ++EL+F +GD LT++ +       WW   L  R+G VP N + L   I
Sbjct: 1023 VAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYPRI 1082

Query: 65   GPMQET 70
             P Q T
Sbjct: 1083 KPRQRT 1088


>gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
            isoform 2 [Homo sapiens]
          Length = 2472

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 7/83 (8%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQE 69
            ALYD   +   E+  +KGDILT++       + WW   ++ RQG VP   VK L  P Q 
Sbjct: 974  ALYDYQEKSPREVTMKKGDILTLLNSTN---KDWWKVEVNDRQGFVPAAYVKKL-DPAQS 1029

Query: 70   TASSH---EQPASGLMQQTFGQQ 89
             +  +   EQ +  L Q+    Q
Sbjct: 1030 ASRENLLEEQGSIALRQEQIDNQ 1052


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,476,359
Number of Sequences: 37866
Number of extensions: 1948210
Number of successful extensions: 5997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 5479
Number of HSP's gapped (non-prelim): 587
length of query: 834
length of database: 18,247,518
effective HSP length: 111
effective length of query: 723
effective length of database: 14,044,392
effective search space: 10154095416
effective search space used: 10154095416
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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