BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5453666 G protein-coupled receptor 19 [Homo sapiens] (415 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5453666 G protein-coupled receptor 19 [Homo sapiens] 847 0.0 gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 141 1e-33 gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 141 1e-33 gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 141 1e-33 gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 139 5e-33 gi|222080109 orexin receptor 2 [Homo sapiens] 126 4e-29 gi|167000885 galanin receptor 1 [Homo sapiens] 123 3e-28 gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 119 4e-27 gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 119 7e-27 gi|4503905 galanin receptor 2 [Homo sapiens] 116 4e-26 gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 116 4e-26 gi|46395496 G protein-coupled receptor for asthma susceptibility... 115 6e-26 gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 115 7e-26 gi|157426873 tachykinin receptor 2 [Homo sapiens] 115 7e-26 gi|222080095 orexin receptor 1 [Homo sapiens] 114 1e-25 gi|46391085 G protein-coupled receptor for asthma susceptibility... 114 2e-25 gi|4557859 somatostatin receptor 2 [Homo sapiens] 113 3e-25 gi|4557857 somatostatin receptor 1 [Homo sapiens] 108 7e-24 gi|4557865 somatostatin receptor 5 [Homo sapiens] 106 3e-23 gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 106 4e-23 gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 105 8e-23 gi|7669548 tachykinin receptor 3 [Homo sapiens] 104 1e-22 gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 103 2e-22 gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 103 2e-22 gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 103 3e-22 gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 103 4e-22 gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 103 4e-22 gi|149944554 somatostatin receptor 4 [Homo sapiens] 102 6e-22 gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 101 1e-21 gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 101 1e-21 >gi|5453666 G protein-coupled receptor 19 [Homo sapiens] Length = 415 Score = 847 bits (2187), Expect = 0.0 Identities = 415/415 (100%), Positives = 415/415 (100%) Query: 1 MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVL 60 MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVL Sbjct: 1 MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVL 60 Query: 61 KPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTP 120 KPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTP Sbjct: 61 KPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTP 120 Query: 121 FVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKA 180 FVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKA Sbjct: 121 FVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKA 180 Query: 181 KKMIAASWIFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLII 240 KKMIAASWIFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLII Sbjct: 181 KKMIAASWIFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLII 240 Query: 241 LFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHP 300 LFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHP Sbjct: 241 LFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHP 300 Query: 301 HEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTI 360 HEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTI Sbjct: 301 HEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTI 360 Query: 361 TTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV 415 TTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV Sbjct: 361 TTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV 415 >gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] Length = 420 Score = 141 bits (355), Expect = 1e-33 Identities = 83/313 (26%), Positives = 152/313 (48%), Gaps = 25/313 (7%) Query: 57 HYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISV 116 +Y+ +P A I + +++ + GN++VC ++ R++ + TN F++++A +DLL+ + Sbjct: 37 YYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGI 96 Query: 117 ASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVS 176 P LL W G+ CK+ Q ++ ++ L++I +DRF +VYP K++ Sbjct: 97 FCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLT 156 Query: 177 REKAKKMIAASWIFDAGFVTPVLF--------FYGSNWDSH--------CNYFLPSSWEG 220 + A +I W+ ++P +Y +S C P+ Sbjct: 157 IKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMR 216 Query: 221 TAYTVIHFLVGFVIPSVLIILFYQKVIKYIWR--IGTDGRTVRRTMNIVPRTKVKTIKMF 278 YT + F ++ P LI++ Y ++ ++R + GR + ++V R K K IKM Sbjct: 217 KIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKML 276 Query: 279 LILNLLFLLSWLPFHVAQLWHPHEQDYKKSSL------VFTAITWISFSSSASKPTLYSI 332 LI+ LLF+LSWLP + + D + L ++ W++F +S+ P +Y Sbjct: 277 LIVALLFILSWLPLWTLMMLSDY-ADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGF 335 Query: 333 YNANFRRGMKETF 345 +N NFRRG +E F Sbjct: 336 FNENFRRGFQEAF 348 >gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] Length = 522 Score = 141 bits (355), Expect = 1e-33 Identities = 83/313 (26%), Positives = 152/313 (48%), Gaps = 25/313 (7%) Query: 57 HYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISV 116 +Y+ +P A I + +++ + GN++VC ++ R++ + TN F++++A +DLL+ + Sbjct: 139 YYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGI 198 Query: 117 ASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVS 176 P LL W G+ CK+ Q ++ ++ L++I +DRF +VYP K++ Sbjct: 199 FCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLT 258 Query: 177 REKAKKMIAASWIFDAGFVTPVLF--------FYGSNWDSH--------CNYFLPSSWEG 220 + A +I W+ ++P +Y +S C P+ Sbjct: 259 IKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMR 318 Query: 221 TAYTVIHFLVGFVIPSVLIILFYQKVIKYIWR--IGTDGRTVRRTMNIVPRTKVKTIKMF 278 YT + F ++ P LI++ Y ++ ++R + GR + ++V R K K IKM Sbjct: 319 KIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKML 378 Query: 279 LILNLLFLLSWLPFHVAQLWHPHEQDYKKSSL------VFTAITWISFSSSASKPTLYSI 332 LI+ LLF+LSWLP + + D + L ++ W++F +S+ P +Y Sbjct: 379 LIVALLFILSWLPLWTLMMLSDY-ADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGF 437 Query: 333 YNANFRRGMKETF 345 +N NFRRG +E F Sbjct: 438 FNENFRRGFQEAF 450 >gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] Length = 423 Score = 141 bits (355), Expect = 1e-33 Identities = 83/313 (26%), Positives = 152/313 (48%), Gaps = 25/313 (7%) Query: 57 HYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISV 116 +Y+ +P A I + +++ + GN++VC ++ R++ + TN F++++A +DLL+ + Sbjct: 40 YYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGI 99 Query: 117 ASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVS 176 P LL W G+ CK+ Q ++ ++ L++I +DRF +VYP K++ Sbjct: 100 FCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLT 159 Query: 177 REKAKKMIAASWIFDAGFVTPVLF--------FYGSNWDSH--------CNYFLPSSWEG 220 + A +I W+ ++P +Y +S C P+ Sbjct: 160 IKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMR 219 Query: 221 TAYTVIHFLVGFVIPSVLIILFYQKVIKYIWR--IGTDGRTVRRTMNIVPRTKVKTIKMF 278 YT + F ++ P LI++ Y ++ ++R + GR + ++V R K K IKM Sbjct: 220 KIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKML 279 Query: 279 LILNLLFLLSWLPFHVAQLWHPHEQDYKKSSL------VFTAITWISFSSSASKPTLYSI 332 LI+ LLF+LSWLP + + D + L ++ W++F +S+ P +Y Sbjct: 280 LIVALLFILSWLPLWTLMMLSDY-ADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGF 338 Query: 333 YNANFRRGMKETF 345 +N NFRRG +E F Sbjct: 339 FNENFRRGFQEAF 351 >gi|223633971 G protein-coupled receptor 83 [Homo sapiens] Length = 423 Score = 139 bits (350), Expect = 5e-33 Identities = 89/296 (30%), Positives = 143/296 (48%), Gaps = 11/296 (3%) Query: 62 PGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPF 121 P A + + + +FS+FGN LVC VI +++R S T+ F+V++A AD++I++ +TPF Sbjct: 68 PTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPF 127 Query: 122 VLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAK 181 L++F W G C V R+ QY + V L +I +DR I++PL ++S K Sbjct: 128 TLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGV 187 Query: 182 KMIAASWIFDAGFVTP-----VLFFYGSNWDSHCNYFLPSSWEGT-----AYTVIHFLVG 231 IA W F P LF + + D + LP E + F++ Sbjct: 188 IYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILL 247 Query: 232 FVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLP 291 +++P ++I + Y +V K +W G + R K KTIKM +++ +LF L W P Sbjct: 248 YILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVLFALCWFP 307 Query: 292 FHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCM 347 + L + ++L F A W + SS+ P +Y N NFR +K M Sbjct: 308 LNCYVLLLSSKVIRTNNALYF-AFHWFAMSSTCYNPFIYCWLNENFRIELKALLSM 362 >gi|222080109 orexin receptor 2 [Homo sapiens] Length = 444 Score = 126 bits (316), Expect = 4e-29 Identities = 86/357 (24%), Positives = 157/357 (43%), Gaps = 48/357 (13%) Query: 74 ILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTL 133 I+++ ++ GN LVC+ + ++ ++ TNYF+V+++ AD+L+++ P L+ T W Sbjct: 63 IVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFF 122 Query: 134 GSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWIFDAG 193 G + CKV+ Y Q ++ V + L I +DR+Y I +PL FK + ++A+ I WI Sbjct: 123 GQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCI 182 Query: 194 FVTPVLF-------FYGSNWDSHCNYFLPSSWEGTAYT----VIHFLVGFVIPSVLIILF 242 + P F G + W G Y + FLV ++ P L++L Sbjct: 183 IMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLA 242 Query: 243 YQKVIKYIW---RIGTDGRTVRRTMNIVP-------------------------RTKVKT 274 Y ++ + +W GT R+ + P R + KT Sbjct: 243 YLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKT 302 Query: 275 IKMFLILNLLFLLSWLPFHVAQL------WHPHEQDYKKSSLVFTAITWISFSSSASKPT 328 +M +I+ L+F + +LP + + H +D + FT W+ +++SA+ P Sbjct: 303 ARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPI 362 Query: 329 LYSIYNANFRRGMKETFCMSSMKCYRSNAYTIT---TSSRMAKKNYVGISEIPSMAK 382 +Y+ + FR K F + + +T TS+ K IS +++K Sbjct: 363 IYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISK 419 >gi|167000885 galanin receptor 1 [Homo sapiens] Length = 349 Score = 123 bits (309), Expect = 3e-28 Identities = 79/288 (27%), Positives = 142/288 (49%), Gaps = 19/288 (6%) Query: 70 IFFGILWLFSIFGNSLVCLVIHRSR--RTQSTTNYFVVSMACADLLISVASTPFVLLQFT 127 + FG+++ + GNSLV V+ RS+ + +STTN F+++++ ADL + PF + Sbjct: 38 VVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYA 97 Query: 128 TGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVY---PLSFKVSREKAKKMI 184 W LG+ CK + YF ++ V I+ L ++ +DR+ IV+ S +VSR A + Sbjct: 98 LPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSR-NALLGV 156 Query: 185 AASWIFDAGFVTPVLFFYG-----SNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLI 239 W +PV + G ++ + C P AY V F+ G+++P +LI Sbjct: 157 GCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLI 216 Query: 240 ILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWH 299 Y KV+ ++ + ++ +K KT + L++ ++F +SWLP H+ LW Sbjct: 217 CFCYAKVLNHL------HKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWA 270 Query: 300 PHEQDYKKSSLVFTAIT--WISFSSSASKPTLYSIYNANFRRGMKETF 345 + IT +++S+S+ P +Y+ + NFR+ K+ F Sbjct: 271 EFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVF 318 >gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] Length = 430 Score = 119 bits (299), Expect = 4e-27 Identities = 75/302 (24%), Positives = 140/302 (46%), Gaps = 31/302 (10%) Query: 70 IFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTG 129 + + +++L + GN+LVC ++ ++R + TN F++++A +DLL+ + P L+ Sbjct: 48 VAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLIT 107 Query: 130 RWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWI 189 W +ATCK+ Q ++ ++ L++I ++RF IV+P K++ KA IA W Sbjct: 108 GWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWA 167 Query: 190 FDAGFVTPVLFFYGSNWDSH--------CNYFLPSSWEG-------TAYTVIHFLVGFVI 234 + P + H +Y L S WE YT + F ++ Sbjct: 168 LALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLA 227 Query: 235 PSVLIILFYQKVIKYIWRI------GTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLS 288 P LI++ Y ++ + + + G + R + R + + + M +++ L F LS Sbjct: 228 PLALIVVMYARIARKLCQAPGPAPGGEEAADPRAS-----RRRARVVHMLVMVALFFTLS 282 Query: 289 WLPFHVAQLWHPH-----EQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKE 343 WLP L + Q + + F W++F +S++ P +Y +N NFRRG + Sbjct: 283 WLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQA 342 Query: 344 TF 345 F Sbjct: 343 AF 344 >gi|157738685 G protein-coupled receptor 103 [Homo sapiens] Length = 431 Score = 119 bits (297), Expect = 7e-27 Identities = 80/309 (25%), Positives = 143/309 (46%), Gaps = 25/309 (8%) Query: 62 PGEVATASIFFGIL-WLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTP 120 PG A + G+L + ++FGN+LV V+ RS+ ++ TN F+ S+A +DLLI+ P Sbjct: 41 PGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIP 100 Query: 121 FVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFK--VSRE 178 +LQ + W G+ CK+V + Q +I + I ++R +V+P K + Sbjct: 101 VTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNR 160 Query: 179 KAKKMIAASWIFDAGFVTPVLF---------FYGSNWDSHCNYFLPSSWEGTAYTVIHFL 229 +A M+ W+ +P+ F C S YT + Sbjct: 161 RAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILV 220 Query: 230 VGFVIPSVLIILFYQKVIKYIW---RIGTDGRTVR----RTMNIVPRTKVKTIKMFLILN 282 + F++P +++++ Y K+ +W R+G DG +R + M+ + R K + + M + + Sbjct: 221 ILFLLPLMVMLILYSKIGYELWIKKRVG-DGSVLRTIHGKEMSKIARKKKRAVIMMVTVV 279 Query: 283 LLFLLSWLPFHVAQLWHPH-----EQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANF 337 LF + W PFHV + + E D ++F + I FS+S P +Y+ N NF Sbjct: 280 ALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENF 339 Query: 338 RRGMKETFC 346 ++ + C Sbjct: 340 KKNVLSAVC 348 >gi|4503905 galanin receptor 2 [Homo sapiens] Length = 387 Score = 116 bits (290), Expect = 4e-26 Identities = 77/295 (26%), Positives = 135/295 (45%), Gaps = 23/295 (7%) Query: 64 EVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVL 123 E + F +++L GN+LV V+ R + STTN F++++ ADL + PF Sbjct: 24 EAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQA 83 Query: 124 LQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSR--EKAK 181 +T W GS CK V + +LT + L ++ +DR+ I YPL + R A Sbjct: 84 TIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNAL 143 Query: 182 KMIAASWIFDAGFVTPVLFFYGSNWDSHCNYFLP--SSWEGTAYTVIHFLVGFVIPSVLI 239 I W F P L +Y + ++ P S+ A + F+ +++P +++ Sbjct: 144 AAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVL 203 Query: 240 ILFYQKVIKYIWR------IGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFH 293 L Y + ++Y+WR G+ R R K K +M LI+ LF L W+P H Sbjct: 204 GLTYARTLRYLWRAVDPVAAGSGAR----------RAKRKVTRMILIVAALFCLCWMPHH 253 Query: 294 --VAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFC 346 + +W + + + +S+++S P +Y++ + +FR+G + T C Sbjct: 254 ALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFR-TIC 307 >gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] Length = 381 Score = 116 bits (290), Expect = 4e-26 Identities = 81/283 (28%), Positives = 130/283 (45%), Gaps = 18/283 (6%) Query: 77 LFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSA 136 L + GNSLV V+ + + ++ TN+F+ ++A ADLL++ PF L G W +G Sbjct: 62 LLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPV 121 Query: 137 TCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWIFDAGFVT 196 C +V Y Q L V L I +DR IVY L K+S+ + +I +W A + Sbjct: 122 LCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLAS 181 Query: 197 PVLFFYGSNWDS--------HCNYFLP---SSWEGTAYTVIHFLVGFVIPSVLIILFYQK 245 P+ F + C P S GT Y++ L+ +V+P +I Y + Sbjct: 182 PLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTR 241 Query: 246 VIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQ-- 303 IW + + + + + KT KM + + ++F +SWLP H QL + Sbjct: 242 ----IWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQV 297 Query: 304 -DYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETF 345 D K+ L+FT I+ S+ + P LY N+N+R+ F Sbjct: 298 LDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAF 340 >gi|46395496 G protein-coupled receptor for asthma susceptibility isoform A [Homo sapiens] Length = 371 Score = 115 bits (289), Expect = 6e-26 Identities = 94/349 (26%), Positives = 156/349 (44%), Gaps = 40/349 (11%) Query: 27 SCTETATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLV 86 +CTET T E+ E W S +Y K ++ T +L++F+I GNS+V Sbjct: 25 ACTETVT------FTEVVEGKEWGS----FYYSFKTEQLIT----LWVLFVFTIVGNSVV 70 Query: 87 CLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQY 146 R R+ +S +FV +A D + + + TG +T C+VVRY Q Sbjct: 71 LFSTWR-RKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQV 129 Query: 147 LTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWIFDAGFVTPVLFFYG--- 203 + YVL+S+ IDR++ IVYP+ F ++A+ +I +W F P L +G Sbjct: 130 VLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRT 189 Query: 204 -SNWDSHCNYFLPSSWEGTAY-TVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTV- 260 SN + C P T Y T++ FLV F IP +I + Y VI+ IW TV Sbjct: 190 LSNGEVQCWALWPDDSYWTPYMTIVAFLVYF-IPLTIISIMYGIVIRTIWIKSKTYETVI 248 Query: 261 ----------RRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWH-----PHEQDY 305 ++ + K+K IK +I+ L F+ W P+ + + P Q+ Sbjct: 249 SNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQER 308 Query: 306 KKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYR 354 +S++ + + +SA P +Y +++++ +E S +R Sbjct: 309 FYASVIIQNLPAL---NSAINPLIYCVFSSSISFPCREQRSQDSRMTFR 354 >gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] Length = 413 Score = 115 bits (288), Expect = 7e-26 Identities = 84/327 (25%), Positives = 147/327 (44%), Gaps = 36/327 (11%) Query: 65 VATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLL 124 V I ++ L +FGN LV I + R Q+ TNYF+ S+ACADL++ +A PF Sbjct: 33 VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAA 92 Query: 125 QFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFK--VSREKAKK 182 WT G+ C+ L I L I +DR++ I P ++ +++ KA+ Sbjct: 93 HILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARV 152 Query: 183 MIAASWIFD--AGFVTPVLFFYGSNWDSHCNYFLPSS----WEGTAYTVIHFLVGFVIPS 236 +I WI F+ + +Y + N + + + AY + +V F +P Sbjct: 153 IILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212 Query: 237 VLIILFYQKV-------------------IKYIWRIGTDGRT---VRRTMNIVPRTKVKT 274 V+++ Y +V ++ + ++ DGRT +RR+ + + K Sbjct: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLK-EHKA 271 Query: 275 IKMFLILNLLFLLSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYN 334 +K I+ F L WLPF + + H + + + V+ + WI + +S P +Y + Sbjct: 272 LKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKE-VYILLNWIGYVNSGFNPLIY-CRS 329 Query: 335 ANFRRGMKETFCM--SSMKCYRSNAYT 359 +FR +E C+ SS+K Y N Y+ Sbjct: 330 PDFRIAFQELLCLRRSSLKAY-GNGYS 355 >gi|157426873 tachykinin receptor 2 [Homo sapiens] Length = 398 Score = 115 bits (288), Expect = 7e-26 Identities = 77/305 (25%), Positives = 136/305 (44%), Gaps = 10/305 (3%) Query: 51 SNQTDLHYVLKPG-EVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMAC 109 SN T + P ++A + + L L ++ GN++V +I RR ++ TNYF+V++A Sbjct: 18 SNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLAL 77 Query: 110 ADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVY 169 ADL ++ + F + + W G A C F V IY + +I DR+ IV+ Sbjct: 78 ADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVH 137 Query: 170 PLSFKVSREKAKKMIAASWIFDAGFVTPVLFFYGSNWD---SHCNYFLPSSWEGTAYTVI 226 P ++S K +IA W+ +P F+ D + C P G + Sbjct: 138 PFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLY 197 Query: 227 HFLV---GFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNL 283 H +V + +P ++ + Y + +WR G + K +K +++ L Sbjct: 198 HLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVL 257 Query: 284 LFLLSWLPFHVAQLWHPHEQD---YKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRG 340 F + WLP+H+ + ++D +K V+ A+ W++ SS+ P +Y N FR G Sbjct: 258 TFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSG 317 Query: 341 MKETF 345 + F Sbjct: 318 FRLAF 322 >gi|222080095 orexin receptor 1 [Homo sapiens] Length = 425 Score = 114 bits (286), Expect = 1e-25 Identities = 81/324 (25%), Positives = 136/324 (41%), Gaps = 59/324 (18%) Query: 75 LWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLG 134 +++ ++ GN+LVCL + R+ ++ TNYF+V+++ AD+L++ P LL T W G Sbjct: 56 VFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFG 115 Query: 135 SATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWIFDAGF 194 A CKV+ Y Q ++ V + L I +DR+Y I +PL FK + +A+ I W Sbjct: 116 HALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAI 175 Query: 195 VTPVLFFYGSNWDSHCNYFLP-------------SSWEGTAYTVIH----FLVGFVIPSV 237 + P C+ LP W Y I+ F+V ++ P Sbjct: 176 MVPQAAV------MECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLG 229 Query: 238 LIILFYQKVIKYIWRIGTDGRTVRRTMN------------------IVPRTKV------- 272 L+ + Y ++ + +W G T N PR + Sbjct: 230 LMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQ 289 Query: 273 -----KTIKMFLILNLLFLLSWLPFHVAQL------WHPHEQDYKKSSLVFTAITWISFS 321 KT KM +++ L+F L +LP V + D + FT W+ ++ Sbjct: 290 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA 349 Query: 322 SSASKPTLYSIYNANFRRGMKETF 345 +SA+ P +Y+ + FR K F Sbjct: 350 NSAANPIIYNFLSGKFREQFKAAF 373 >gi|46391085 G protein-coupled receptor for asthma susceptibility isoform B [Homo sapiens] Length = 377 Score = 114 bits (285), Expect = 2e-25 Identities = 91/331 (27%), Positives = 151/331 (45%), Gaps = 40/331 (12%) Query: 27 SCTETATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLV 86 +CTET T E+ E W S +Y K ++ T +L++F+I GNS+V Sbjct: 25 ACTETVT------FTEVVEGKEWGS----FYYSFKTEQLIT----LWVLFVFTIVGNSVV 70 Query: 87 CLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQY 146 R R+ +S +FV +A D + + + TG +T C+VVRY Q Sbjct: 71 LFSTWR-RKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQV 129 Query: 147 LTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWIFDAGFVTPVLFFYG--- 203 + YVL+S+ IDR++ IVYP+ F ++A+ +I +W F P L +G Sbjct: 130 VLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRT 189 Query: 204 -SNWDSHCNYFLPSSWEGTAY-TVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTV- 260 SN + C P T Y T++ FLV F IP +I + Y VI+ IW TV Sbjct: 190 LSNGEVQCWALWPDDSYWTPYMTIVAFLVYF-IPLTIISIMYGIVIRTIWIKSKTYETVI 248 Query: 261 ----------RRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWH-----PHEQDY 305 ++ + K+K IK +I+ L F+ W P+ + + P Q+ Sbjct: 249 SNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQER 308 Query: 306 KKSSLVFTAITWISFSSSASKPTLYSIYNAN 336 +S++ + + +SA P +Y +++++ Sbjct: 309 FYASVIIQNLPAL---NSAINPLIYCVFSSS 336 >gi|4557859 somatostatin receptor 2 [Homo sapiens] Length = 369 Score = 113 bits (283), Expect = 3e-25 Identities = 78/307 (25%), Positives = 147/307 (47%), Gaps = 18/307 (5%) Query: 51 SNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACA 110 SNQT+ +Y L V T F ++ + + GN+LV VI R + ++ TN +++++A A Sbjct: 31 SNQTEPYYDLTSNAVLTFIYF--VVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIA 88 Query: 111 DLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYP 170 D L + PF+ +Q W G A C+VV + I+ L + IDR+ +V+P Sbjct: 89 DELFMLG-LPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHP 147 Query: 171 L-SFKVSREKAKKMIA-ASWIFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEG------TA 222 + S K R + KMI A W + P++ + G + +W G T Sbjct: 148 IKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTG 207 Query: 223 YTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILN 282 + + F++GF++P +I L Y +I + G + +R +++ K +M I+ Sbjct: 208 FIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKR-----KKSEKKVTRMVSIVV 262 Query: 283 LLFLLSWLPFHVAQLWHPHEQDYKKSSL--VFTAITWISFSSSASKPTLYSIYNANFRRG 340 +F+ WLPF++ + +L +F + +++++S + P LY+ + NF++ Sbjct: 263 AVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKS 322 Query: 341 MKETFCM 347 + C+ Sbjct: 323 FQNVLCL 329 >gi|4557857 somatostatin receptor 1 [Homo sapiens] Length = 391 Score = 108 bits (271), Expect = 7e-24 Identities = 75/299 (25%), Positives = 143/299 (47%), Gaps = 22/299 (7%) Query: 63 GEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFV 122 G S + ++ L + GNS+V VI R + ++ TN +++++A AD L+ + S PF+ Sbjct: 56 GSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELL-MLSVPFL 114 Query: 123 LLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREK--- 179 + W G+ C++V + IY L + +DR+ +V+P+ K +R + Sbjct: 115 VTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPI--KAARYRRPT 172 Query: 180 -AKKMIAASWIFDAGFVTPVLFF----YGSNWDSHCNYFLPSSWEG--TAYTVIHFLVGF 232 AK + W+ + P++ F S+ CN +P + + + FL+GF Sbjct: 173 VAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGF 232 Query: 233 VIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPF 292 ++P I L Y +I + + +R R++ K M +++ ++F++ W+PF Sbjct: 233 LLPVGAICLCYVLIIAKMRMVALKAGWQQR-----KRSERKITLMVMMVVMVFVICWMPF 287 Query: 293 HVAQLWHPH-EQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSM 350 +V QL + EQD + V + +++S + P LY + NF+R + C+S M Sbjct: 288 YVVQLVNVFAEQD---DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWM 343 >gi|4557865 somatostatin receptor 5 [Homo sapiens] Length = 364 Score = 106 bits (265), Expect = 3e-23 Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 17/274 (6%) Query: 82 GNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVV 141 GN+LV V+ R + ++ TN +++++A AD+L + PF+ Q W G C++V Sbjct: 57 GNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLG-LPFLATQNAASFWPFGPVLCRLV 115 Query: 142 RYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREK--AKKMIAASWIFDAGFVTPVL 199 + ++ L + +DR+ +V+PLS R AK AA+W+ P+L Sbjct: 116 MTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLL 175 Query: 200 FFYGSNWDSHCNYFLPSS---WEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTD 256 F CN P W G + + ++GF P ++I L Y ++ + G Sbjct: 176 VFADVQEGGTCNASWPEPVGLW-GAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVR 234 Query: 257 GRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPF---HVAQLWHPHEQDYKKSSLVFT 313 VRR R++ K +M L++ L+F WLPF ++ L Q+ + L F Sbjct: 235 VGCVRR------RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFF 288 Query: 314 AITWISFSSSASKPTLYSIYNANFRRGMKETFCM 347 + +S+++S + P LY + NFR+ ++ C+ Sbjct: 289 VVI-LSYANSCANPVLYGFLSDNFRQSFQKVLCL 321 >gi|62865887 G protein-coupled receptor 54 [Homo sapiens] Length = 398 Score = 106 bits (264), Expect = 4e-23 Identities = 74/293 (25%), Positives = 132/293 (45%), Gaps = 24/293 (8%) Query: 70 IFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTG 129 +FF L L + GNSLV VI R + ++ TN+++ ++A D+ + PF L + Sbjct: 47 LFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLP 106 Query: 130 RWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAAS-- 187 W LG CK V Y Q ++ L ++ +DR+Y V+PL + R + +A S Sbjct: 107 GWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLR-ALHRRTPRLALAVSLS 165 Query: 188 -WIFDAGFVTPVLFFY--GSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQ 244 W+ A PVL + ++C+ PS A+ + + L +++P + Y Sbjct: 166 IWVGSAAVSAPVLALHRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYA 225 Query: 245 KVIKYIWRIGT---------DGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLP---F 292 +++++ R+ G+ + V + K ++ + LLF W P F Sbjct: 226 AMLRHLGRVAVRPAPADSALQGQVLAERAGAV---RAKVSRLVAAVVLLFAACWGPIQLF 282 Query: 293 HVAQLWHPHEQDYKKSSLVFTAITW---ISFSSSASKPTLYSIYNANFRRGMK 342 V Q P + +S + TW +S+S+SA P LY+ ++FR+ + Sbjct: 283 LVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFR 335 >gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sapiens] Length = 351 Score = 105 bits (262), Expect = 8e-23 Identities = 74/287 (25%), Positives = 126/287 (43%), Gaps = 12/287 (4%) Query: 65 VATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLL 124 VA S G +++ +IFGN + + I ++ + TN+ ++SMA D L+ P+ ++ Sbjct: 44 VAMYSFMAGSIFI-TIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMI 102 Query: 125 QFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPL--SFKVSREKAKK 182 + W G CK+ F + I+ L S+ IDRFY I YPL S K++ K+ Sbjct: 103 RSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKR 162 Query: 183 MIAASWIFDAGFVTPVLF--FYGSNWDSH-----CNYFLPSSWEGTAYTVIHFLVGFVIP 235 ++ W F V+F Y + + C+ P + T + F+ GF P Sbjct: 163 LLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTL-FMAGFFTP 221 Query: 236 SVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVA 295 +++ Y K+ + +R N + K K I+ +FLL W P Sbjct: 222 GSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFT 281 Query: 296 QLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMK 342 L P ++ ++F A+TW + +S P +Y + FRR +K Sbjct: 282 ILLDPF-LNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALK 327 >gi|7669548 tachykinin receptor 3 [Homo sapiens] Length = 465 Score = 104 bits (260), Expect = 1e-22 Identities = 76/321 (23%), Positives = 140/321 (43%), Gaps = 19/321 (5%) Query: 32 ATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIH 91 A+P PSQ L+ + +V +A S+ +G++ ++ GN +V +I Sbjct: 63 ASPAPSQPWANLTNQ-----------FVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIIL 111 Query: 92 RSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGV 151 +R ++ TNYF+V++A +D ++ +T + W G+ C+ +F Sbjct: 112 AHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFA 171 Query: 152 QIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWIFDAGFVTPVLFFYGSNWDSHCN 211 IY + +I +DR+ I+ PL ++S K +I + WI P + + Sbjct: 172 SIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRT 231 Query: 212 YFLPSSWEGT----AYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIV 267 EG Y +I ++ + P +++ + Y V +W G T + + Sbjct: 232 LCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQL 291 Query: 268 PRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQD---YKKSSLVFTAITWISFSSSA 324 + K K +KM +I+ + F + WLP+H+ + Q +K V+ A W++ SS+ Sbjct: 292 -KAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTM 350 Query: 325 SKPTLYSIYNANFRRGMKETF 345 P +Y N FR G K F Sbjct: 351 YNPIIYCCLNKRFRAGFKRAF 371 >gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] Length = 420 Score = 103 bits (258), Expect = 2e-22 Identities = 82/362 (22%), Positives = 161/362 (44%), Gaps = 44/362 (12%) Query: 67 TASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQF 126 T + I+ + +FGN LV VI R + ++ TN ++ ++A AD L + ++ PF + + Sbjct: 72 TIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNY 130 Query: 127 TTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYP---LSFKVSREKAKKM 183 G W G+ CK+V Y I+ L ++ +DR+ + +P L F+ R AK + Sbjct: 131 LMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR-NAKII 189 Query: 184 IAASWIFDAGFVTPVLFFYGSNW-----DSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVL 238 +WI + PV+F + + D + P+ + + F+ F++P ++ Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 249 Query: 239 IILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLW 298 I + Y +I + + + + N+ + +M L++ +F++ W P H+ + Sbjct: 250 ITVCYGLMILRLKSVRMLSGSKEKDRNL-----RRITRMVLVVVAVFIVCWTPIHIYVI- 303 Query: 299 HPHEQDYKKSSLVFTAITW-----ISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCY 353 + F ++W + +++S P LY+ + NF+R C+ Sbjct: 304 --IKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKR------------CF 349 Query: 354 RSNAYTITTSSRMAKKNYVGI----SEIPSMAKTI--TKDSIYDSFDREAKEKKLAWPIN 407 R + I TSS + ++N I + PS A T+ T + + D + K WP++ Sbjct: 350 RE--FCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQVELNLDCHCENAK-PWPLS 406 Query: 408 SN 409 N Sbjct: 407 YN 408 >gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sapiens] Length = 306 Score = 103 bits (258), Expect = 2e-22 Identities = 70/273 (25%), Positives = 119/273 (43%), Gaps = 11/273 (4%) Query: 79 SIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATC 138 +IFGN + + I ++ + TN+ ++SMA D L+ P+ +++ W G C Sbjct: 12 TIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFC 71 Query: 139 KVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPL--SFKVSREKAKKMIAASWIFDAGFVT 196 K+ F + I+ L S+ IDRFY I YPL S K++ K+++ W F Sbjct: 72 KIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAF 131 Query: 197 PVLF--FYGSNWDSH-----CNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKY 249 V+F Y + + C+ P + T + F+ GF P +++ Y K+ Sbjct: 132 GVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTL-FMAGFFTPGSMMVGIYGKIFAV 190 Query: 250 IWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQDYKKSS 309 + +R N + K K I+ +FLL W P L P ++ Sbjct: 191 SRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPF-LNFSTPV 249 Query: 310 LVFTAITWISFSSSASKPTLYSIYNANFRRGMK 342 ++F A+TW + +S P +Y + FRR +K Sbjct: 250 VLFDALTWFGYFNSTCNPLIYGFFYPWFRRALK 282 >gi|4758474 G protein-coupled receptor 10 [Homo sapiens] Length = 370 Score = 103 bits (257), Expect = 3e-22 Identities = 71/284 (25%), Positives = 131/284 (46%), Gaps = 10/284 (3%) Query: 70 IFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQ-FTT 128 + + ++ + + GN L+ LVI R RR + TN+ + ++A +D+L+ A P L F Sbjct: 65 LLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEP 124 Query: 129 GRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASW 188 W G C +V + Q +T V ++ L +I +DR+ +V+PL ++S + + A W Sbjct: 125 RGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIW 184 Query: 189 IFDAGFVTP-VLFFYGSNWDSH----CNYFLPS-SWEGTAYTVIHFLVGFVIPSVLIILF 242 A P + Y H C F S + Y LV +++P ++I+L Sbjct: 185 ALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLS 244 Query: 243 YQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWH--- 299 Y +V + G + + + +T + +++ ++F + WLP HV L Sbjct: 245 YVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLD 304 Query: 300 PHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKE 343 PH D LV W++ SS+ P +Y+ + +FR +++ Sbjct: 305 PHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRK 348 >gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] Length = 397 Score = 103 bits (256), Expect = 4e-22 Identities = 74/311 (23%), Positives = 138/311 (44%), Gaps = 24/311 (7%) Query: 67 TASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQF 126 T ++ +L L ++ GN +VCL + +RR ++ TN F+VS+A DLL+ + PF + Sbjct: 20 TITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQ 79 Query: 127 TTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIA- 185 + +W+ G C + + I L I +DR+ ++ PL + V + I+ Sbjct: 80 LSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISL 139 Query: 186 -ASWIFD--AGFVTPVLFFYGSNWDSHCNYFLPSS--WEGTAYTVIHFLVGFVIPSVLII 240 W+ F++ L + N S N+ Y ++ LV F +P +++ Sbjct: 140 VLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMC 199 Query: 241 LFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLL------FLLSWLPFHV 294 + Y ++ K R + +N + K TI+ L F++ W P+ Sbjct: 200 ITYYRIFKV-------ARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFT 252 Query: 295 AQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYR 354 A ++ D + ++ + W+ +++SA P LY+ N +FR G ++ FC C Sbjct: 253 AFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFC-----CRL 307 Query: 355 SNAYTITTSSR 365 +N + TS R Sbjct: 308 ANRNSHKTSLR 318 >gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] Length = 359 Score = 103 bits (256), Expect = 4e-22 Identities = 74/311 (23%), Positives = 138/311 (44%), Gaps = 24/311 (7%) Query: 67 TASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQF 126 T ++ +L L ++ GN +VCL + +RR ++ TN F+VS+A DLL+ + PF + Sbjct: 20 TITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQ 79 Query: 127 TTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIA- 185 + +W+ G C + + I L I +DR+ ++ PL + V + I+ Sbjct: 80 LSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISL 139 Query: 186 -ASWIFD--AGFVTPVLFFYGSNWDSHCNYFLPSS--WEGTAYTVIHFLVGFVIPSVLII 240 W+ F++ L + N S N+ Y ++ LV F +P +++ Sbjct: 140 VLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMC 199 Query: 241 LFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLL------FLLSWLPFHV 294 + Y ++ K R + +N + K TI+ L F++ W P+ Sbjct: 200 ITYYRIFKV-------ARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFT 252 Query: 295 AQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYR 354 A ++ D + ++ + W+ +++SA P LY+ N +FR G ++ FC C Sbjct: 253 AFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFC-----CRL 307 Query: 355 SNAYTITTSSR 365 +N + TS R Sbjct: 308 ANRNSHKTSLR 318 >gi|149944554 somatostatin receptor 4 [Homo sapiens] Length = 388 Score = 102 bits (254), Expect = 6e-22 Identities = 75/301 (24%), Positives = 135/301 (44%), Gaps = 20/301 (6%) Query: 59 VLKPGEVATASI-----FFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLL 113 V PG+ A + + ++ L + GN+LV VI R + ++ TN +++++A AD L Sbjct: 36 VAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADEL 95 Query: 114 ISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSF 173 + S PFV W GS C+ V L ++ L + +DR+ +V+PL Sbjct: 96 FML-SVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRA 154 Query: 174 KVSREK--AKKMIAASWIFDAGFVTPVLFFYGS-----NWDSHCNYFLPSSWEGTAYTVI 226 R AK + W+ P+ F + CN P + V Sbjct: 155 ATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVY 214 Query: 227 HFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFL 286 FL+GF++P + I L Y ++ + + +R R++ K ++ L++ ++F+ Sbjct: 215 TFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRR-----RSEKKITRLVLMVVVVFV 269 Query: 287 LSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFC 346 L W+PF+V QL + + + I +S+++S + P LY + NFRR + C Sbjct: 270 LCWMPFYVVQLLNLFVTSLDATVNHVSLI--LSYANSCANPILYGFLSDNFRRFFQRVLC 327 Query: 347 M 347 + Sbjct: 328 L 328 >gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] Length = 397 Score = 101 bits (252), Expect = 1e-21 Identities = 79/351 (22%), Positives = 157/351 (44%), Gaps = 45/351 (12%) Query: 67 TASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQF 126 T + I+ + +FGN LV VI R + ++ TN ++ ++A AD L + ++ PF + + Sbjct: 72 TIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNY 130 Query: 127 TTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYP---LSFKVSREKAKKM 183 G W G+ CK+V Y I+ L ++ +DR+ + +P L F+ R AK + Sbjct: 131 LMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR-NAKII 189 Query: 184 IAASWIFDAGFVTPVLFFYGSNW-----DSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVL 238 +WI + PV+F + + D + P+ + + F+ F++P ++ Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 249 Query: 239 IILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLW 298 I + Y +I + + + + N+ + +M L++ +F++ W P H+ + Sbjct: 250 ITVCYGLMILRLKSVRMLSGSKEKDRNL-----RRITRMVLVVVAVFIVCWTPIHIYVI- 303 Query: 299 HPHEQDYKKSSLVFTAITW-----ISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCY 353 + F ++W + +++S P LY+ + NF+R C+ Sbjct: 304 --IKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKR------------CF 349 Query: 354 RSNAYTITTSSRMAKKNYVGI----SEIPSMAKTITKDSIYDSFDREAKEK 400 R + I TSS + ++N I + PS A T+ + + RE ++K Sbjct: 350 RE--FCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDR----TNHQRERRQK 394 >gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] Length = 407 Score = 101 bits (252), Expect = 1e-21 Identities = 77/310 (24%), Positives = 135/310 (43%), Gaps = 21/310 (6%) Query: 51 SNQTDLHYVLKPG-EVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMAC 109 +N ++ + ++P ++ + + ++ + S+ GN +V +I +R ++ TNYF+V++A Sbjct: 17 TNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAF 76 Query: 110 ADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVY 169 A+ ++ +T W G CK +F IY + ++ DR+ I++ Sbjct: 77 AEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIH 136 Query: 170 PLSFKVSREKAKKMIAASWI------FDAGFVT-----PVLFFYGSNWDSHCNYFLPSSW 218 PL ++S K +I W+ F G+ + P W H N + Sbjct: 137 PLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVY 196 Query: 219 EGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMF 278 +I+FL P ++I Y V +W G + R V K K +KM Sbjct: 197 HICVTVLIYFL-----PLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV-SAKRKVVKMM 250 Query: 279 LILNLLFLLSWLPFHVAQLWHPHEQD-YKKSSL--VFTAITWISFSSSASKPTLYSIYNA 335 +++ F + WLPFH+ L D Y K + V+ AI W++ SS+ P +Y N Sbjct: 251 IVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLND 310 Query: 336 NFRRGMKETF 345 FR G K F Sbjct: 311 RFRLGFKHAF 320 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.326 0.136 0.427 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,035,258 Number of Sequences: 37866 Number of extensions: 590982 Number of successful extensions: 2842 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 538 Number of HSP's successfully gapped in prelim test: 118 Number of HSP's that attempted gapping in prelim test: 1668 Number of HSP's gapped (non-prelim): 774 length of query: 415 length of database: 18,247,518 effective HSP length: 105 effective length of query: 310 effective length of database: 14,271,588 effective search space: 4424192280 effective search space used: 4424192280 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.