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Search of human proteins with 5453603
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
(535 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 1029 0.0
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 297 1e-80
gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 294 2e-79
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 273 4e-73
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 261 1e-69
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 227 2e-59
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 221 1e-57
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 217 2e-56
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 214 2e-55
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 196 4e-50
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 192 5e-49
gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 175 8e-44
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 162 7e-40
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 160 3e-39
gi|7657253 T-complex protein 1 [Homo sapiens] 144 3e-34
gi|41399285 chaperonin [Homo sapiens] 86 1e-16
gi|31542947 chaperonin [Homo sapiens] 86 1e-16
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] 49 2e-05
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] 49 2e-05
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 47 3e-05
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 42 0.002
gi|109638749 signal recognition particle 72kDa [Homo sapiens] 32 1.9
gi|153082755 interferon-induced protein with tetratricopeptide r... 31 3.2
gi|4502163 apolipoprotein D precursor [Homo sapiens] 30 5.5
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] 30 7.2
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] 30 7.2
>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
Length = 535
Score = 1029 bits (2661), Expect = 0.0
Identities = 535/535 (100%), Positives = 535/535 (100%)
Query: 1 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS 60
MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
Sbjct: 1 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS 60
Query: 61 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK 120
LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
Sbjct: 61 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK 120
Query: 121 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT 180
IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
Sbjct: 121 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT 180
Query: 181 KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA 240
KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA
Sbjct: 181 KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA 240
Query: 241 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP 300
NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP
Sbjct: 241 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP 300
Query: 301 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI 360
EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI
Sbjct: 301 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI 360
Query: 361 HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA 420
HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA
Sbjct: 361 HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA 420
Query: 421 VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM 480
VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM
Sbjct: 421 VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM 480
Query: 481 REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC 535
REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
Sbjct: 481 REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC 535
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 297 bits (761), Expect = 1e-80
Identities = 183/527 (34%), Positives = 290/527 (55%), Gaps = 9/527 (1%)
Query: 8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67
PV + K G D + +++ I + V++TLGP+GMDK+++ A+ ++NDG
Sbjct: 5 PVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKAT--ISNDG 62
Query: 68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127
ATILK + V +PAAK LVD+++ QD EVGDGTTSVT+LAAE L++ + + + +HPQ II
Sbjct: 63 ATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIII 122
Query: 128 AGWREATKAAREALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEA 186
+R AT+ A + AV +D+V+ R+ L A T LSSKL++ K F K+ V+A
Sbjct: 123 RAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDA 182
Query: 187 VLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANT 242
V+ L L+ I I K GG+L DS L G K QPK+ N KI + N
Sbjct: 183 VMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNV 242
Query: 243 GMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQ 302
++ K + + +RV + I AE + +K+E+I G +++ I + Q
Sbjct: 243 ELEL-KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQ 301
Query: 303 LFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHF 362
F + ++R + GG I ++ + LG C++ EE IG ++ F
Sbjct: 302 YFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFF 361
Query: 363 SGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVT 422
+G + CT +LRG +Q ++E ERSLHDA+ ++ + +K+ V GGG EM ++ +
Sbjct: 362 TGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLR 421
Query: 423 QLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMRE 482
+ PGK+ + + +YAKAL ++P + DNAG+D+ +++ +LRA H++G T G+D+
Sbjct: 422 DYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINN 481
Query: 483 GTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRV 529
I D + E V+ L +A+EAA +I+ VD IK PR V
Sbjct: 482 EDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTV 527
>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
Length = 556
Score = 294 bits (752), Expect = 2e-79
Identities = 193/547 (35%), Positives = 305/547 (55%), Gaps = 30/547 (5%)
Query: 8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67
P+++F D ET R + + A +I ++VKS+LGP G+DK+L+ D + +TNDG
Sbjct: 4 PLSVF---GDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVT--ITNDG 58
Query: 68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127
ATILK + V++PAAKVL +++ +QD EVGDGTTSV ++AAELL+ A+ L+ +KIHP ++I
Sbjct: 59 ATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVI 118
Query: 128 AGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAV 187
+G+R A K A + + + + +DE+ R L+N A T++SSK++ + D F + V+AV
Sbjct: 119 SGYRLACKEAVRYINENLIVN-TDELG-RDCLINAAKTSMSSKIIGINGDFFANMVVDAV 176
Query: 188 LRLKGSG-------NLEAIHIIKKLGGSLADSYLDEGFLLDKKIG-VNQPKRIENAKILI 239
L +K + + +++I+K G S +S L G+ L+ +G PKRI NAKI
Sbjct: 177 LAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIAC 236
Query: 240 ANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNY 299
+ + K+K+ G +V + K+ +I E + KE++++IL G N + I +
Sbjct: 237 LDFSLQKTKMKL-GVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDM 295
Query: 300 PEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTF------DHPELVKLGSCKLIEEVM 353
+ F AG MA+ ++R+A +G I ST + E LG + + +
Sbjct: 296 CLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQER 355
Query: 354 IGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCS 413
I +D+LI + +I+LRGA + DE ERSLHDALCV+ + ++ V GGG
Sbjct: 356 ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAV 415
Query: 414 EMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN 473
E ++ + A +E +A+ +A++L ++P +A NA DS DLVA+LRA H+E
Sbjct: 416 EAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQ 475
Query: 474 TT--------AGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAP 525
GLD+ G D G+ E VK + L A EAA ILR+D++IK P
Sbjct: 476 VNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHP 535
Query: 526 RKRVPDH 532
+ H
Sbjct: 536 ESKDDKH 542
>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
sapiens]
Length = 541
Score = 273 bits (697), Expect = 4e-73
Identities = 172/501 (34%), Positives = 277/501 (55%), Gaps = 12/501 (2%)
Query: 30 IGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSR 89
+ A A+ + ++++LGP G+DK+++ +D + VTNDGATIL + VD+ AK++V++S+
Sbjct: 39 MAAKAVANTMRTSLGPNGLDKMMVD--KDGDVTVTNDGATILSMMDVDHQIAKLMVELSK 96
Query: 90 VQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHG 149
QDDE+GDGTT V VLA LL EAE L+ + IHP I G+ +A + A E L D
Sbjct: 97 SQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHL-DKISDSV 155
Query: 150 SDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL----KGSGNLEAIHIIKKL 205
++K + L+ A TTL SK++ ++AV AVL + + + E I + K+
Sbjct: 156 LVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKV 215
Query: 206 GGSLADSYLDEGFLLDKKIGVNQ-PKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKV 264
GG L D+ L +G ++DK Q PK++E+AKI I + K K ++ V S
Sbjct: 216 GGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKT-KHKLDVTSVEDY 274
Query: 265 AEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLA 324
++ EKEK +E +++I + G N I + + L + A+ +E +A
Sbjct: 275 KALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIA 334
Query: 325 LVTGGEIASTFDHPELVKLGSCKLIEEVMIG--EDKLIHFSGVALGEACTIVLRGATQQI 382
+ TGG I F KLG L++E+ G +DK++ A TI +RG + I
Sbjct: 335 IATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMI 394
Query: 383 LDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKA 442
++EA+RSLHDALCV+ ++D+R VYGGG +E+ A AV+Q A++ P E AM ++A A
Sbjct: 395 IEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADA 454
Query: 443 LRMLPTIIADNAGYDSADLVAQLRAAH-SEGNTTAGLDMREGTIGDMAILGITESFQVKR 501
L ++P +++N+G + + ++RA E N G+D DM + E+ K+
Sbjct: 455 LEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKK 514
Query: 502 QVLLSAAEAAEVILRVDNIIK 522
Q + A + +IL++D+I K
Sbjct: 515 QQISLATQMVRMILKIDDIRK 535
>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
Length = 539
Score = 261 bits (666), Expect = 1e-69
Identities = 164/517 (31%), Positives = 284/517 (54%), Gaps = 18/517 (3%)
Query: 17 DEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGV 76
D ++ R ++ A A+ D ++++LGPKGMDK++ D + +TNDGATILK + V
Sbjct: 26 DRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVT--ITNDGATILKQMQV 83
Query: 77 DNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKA 136
+PAA++LV++S+ QD E GDGTTSV ++A LL L+ K IHP I +++A +
Sbjct: 84 LHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEK 143
Query: 137 AREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL-----K 191
E L + E+ R+ L+N A T+L+SK+++ + + ++V AV+++
Sbjct: 144 GIEILTDMS---RPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATA 200
Query: 192 GSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKI 251
S +L I I+KKLGG++ D L EG +L +K+ + R+E AKI + + K +
Sbjct: 201 TSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITRVEKAKIGLIQFCLSAPKTDM 260
Query: 252 FGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCF-----INRQLIYNYPEQLFGA 306
+++ V A++ + E+ + V++I K G N I R + +
Sbjct: 261 -DNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNK 319
Query: 307 AGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMI-GEDKLIHFSGV 365
+M I+ + +E + G + + D LGS +L EEV + G KL+ +G
Sbjct: 320 MKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGC 379
Query: 366 AL-GEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQL 424
A G+ TIV+RG+ + +++EAERS+HDALCV+ VK + GGG E+ +A +T+
Sbjct: 380 ASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEY 439
Query: 425 ANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGT 484
+ G E+ + ++A A+ ++P+ +A+NAG + V +LR H++G TAG+++R+G
Sbjct: 440 SRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGG 499
Query: 485 IGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNII 521
I ++ + + V L A E IL++D+++
Sbjct: 500 ISNILEELVVQPLLVSVSALTLATETVRSILKIDDVV 536
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 227 bits (579), Expect = 2e-59
Identities = 159/532 (29%), Positives = 275/532 (51%), Gaps = 20/532 (3%)
Query: 8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67
PV + E + + A I D++++ LGPK M K+LL +++TNDG
Sbjct: 6 PVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPM--GGIVMTNDG 63
Query: 68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127
IL+ I V +PAAK ++++SR QD+EVGDGTTSV +LA E+L AE + +++HP +I
Sbjct: 64 NAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVI 123
Query: 128 AGWREATKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
+ +R+A L +S VD ++ ++NI +++++K ++ +A++
Sbjct: 124 SAYRKALDDMISTLKKISIPVDISDSDM-----MLNIINSSITTKAISRWSSLACNIALD 178
Query: 186 AVLRLKGSGNLEAIHIIKKL-------GGSLADSYLDEGFLLDKKIGVNQPKR-IENAKI 237
AV ++ N IKK GG + DS + G +++K + + +R I+N +I
Sbjct: 179 AVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRI 238
Query: 238 LIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIY 297
++ ++ ++ K + + + + I E+E +++ E I++ + I + I
Sbjct: 239 VLLDSSLEYKKGES-QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGIS 297
Query: 298 NYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGS-CKLIEEVMIGE 356
+ + A + AI R+A G I S + +G+ L+E IG+
Sbjct: 298 DLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD 357
Query: 357 DKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEML 416
+ + +ACTI+LRGA+++IL E ER+L DA+ V + D + V GGG SEM
Sbjct: 358 EYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMA 417
Query: 417 MAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN-TT 475
+AHA+T+ + G E + A+AL ++P + N G + L+ LRA H++ N T
Sbjct: 418 VAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCET 477
Query: 476 AGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527
G++ GT+ DM LGI E VK Q +A E A ++LR+D+I+ +K
Sbjct: 478 WGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 529
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 221 bits (563), Expect = 1e-57
Identities = 158/532 (29%), Positives = 274/532 (51%), Gaps = 21/532 (3%)
Query: 8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67
PV + E + + A I D++++ LGPK M K+LL +++TNDG
Sbjct: 6 PVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPM--GGIVMTNDG 63
Query: 68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127
IL+ I V +PAAK ++++SR QD+EVGDGTTSV +L E+L AE + +++HP +I
Sbjct: 64 NAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILG-EMLSVAEHFLEQQMHPTVVI 122
Query: 128 AGWREATKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
+ +R+A L +S VD ++ ++NI +++++K ++ +A++
Sbjct: 123 SAYRKALDDMISTLKKISIPVDISDSDM-----MLNIINSSITTKAISRWSSLACNIALD 177
Query: 186 AVLRLKGSGNLEAIHIIKKL-------GGSLADSYLDEGFLLDKKIGVNQPKR-IENAKI 237
AV ++ N IKK GG + DS + G +++K + + +R I+N +I
Sbjct: 178 AVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRI 237
Query: 238 LIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIY 297
++ ++ ++ K + + + + I E+E +++ E I++ + I + I
Sbjct: 238 VLLDSSLEYKKGES-QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGIS 296
Query: 298 NYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGS-CKLIEEVMIGE 356
+ + A + AI R+A G I S + +G+ L+E IG+
Sbjct: 297 DLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD 356
Query: 357 DKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEML 416
+ + +ACTI+LRGA+++IL E ER+L DA+ V + D + V GGG SEM
Sbjct: 357 EYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMA 416
Query: 417 MAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN-TT 475
+AHA+T+ + G E + A+AL ++P + N G + L+ LRA H++ N T
Sbjct: 417 VAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCET 476
Query: 476 AGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527
G++ GT+ DM LGI E VK Q +A E A ++LR+D+I+ +K
Sbjct: 477 WGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 528
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 217 bits (553), Expect = 2e-56
Identities = 152/536 (28%), Positives = 278/536 (51%), Gaps = 30/536 (5%)
Query: 6 LAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTN 65
+A + + A+ RA A + A + D++++ LGPKG K+L+S D L T
Sbjct: 1 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKL--TK 58
Query: 66 DGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQT 125
DG +L + + +P A ++ ++ QDD GDGTTS ++ ELL++A+ I++ +HP+
Sbjct: 59 DGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRI 118
Query: 126 IIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
I G+ A A E L V + E+K R+ L+++A T+L +K+ D T++ V+
Sbjct: 119 IAEGFEAAKIKALEVLEEVKV---TKEMK-RKILLDVARTSLQTKVHAELADVLTEVVVD 174
Query: 186 AVLRLKGSGN------LEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQP---KRIENAK 236
+VL ++ G +E + + KLG D+ L +G +LD G P KR+E+A
Sbjct: 175 SVLAVRRPGYPIDLFMVEIMEMKHKLG---TDTKLIQGLVLDH--GARHPDMKKRVEDAF 229
Query: 237 ILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERI--LKHGINC----- 289
ILI N ++ +K ++ S + + ++ AE++ ++++V++I LK +
Sbjct: 230 ILICNVSLEYEKTEV-NSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKG 288
Query: 290 --FINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCK 347
IN++ I + G++A+ A +ERL+L GG ++F+ + LG
Sbjct: 289 FVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAG 348
Query: 348 LIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTV 407
L+ E +GE+K + T++++G + L + + ++ D L + ++D V
Sbjct: 349 LVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMV 408
Query: 408 YGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRA 467
G G E+ MA A+ N G+ + ++++A AL ++P ++A NAGYD + + +++A
Sbjct: 409 PGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQA 468
Query: 468 AHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKA 523
H E G+D+ G A G+ +++ VK+Q+L S A IL VD I++A
Sbjct: 469 EHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 524
>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
sapiens]
Length = 531
Score = 214 bits (545), Expect = 2e-55
Identities = 149/533 (27%), Positives = 271/533 (50%), Gaps = 24/533 (4%)
Query: 6 LAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTN 65
+A V A+ RA+ A + A + D++++ LGPKG K+L+S D L T
Sbjct: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKL--TK 58
Query: 66 DGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQT 125
DG +L + + +P A ++ ++ QDD GDGTTS ++ ELL++A+ I++ +HP+
Sbjct: 59 DGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRI 118
Query: 126 IIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
I G+ A + A + L V D R+ L+++A T+L +K+ D T+ V+
Sbjct: 119 ITEGFEAAKEKALQFLEEVKVSREMD----RETLIDVARTSLRTKVHAELADVLTEAVVD 174
Query: 186 AVLRLKGSG---NLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQP---KRIENAKILI 239
++L +K +L I I++ S D+ L G +LD G P KR+E+A IL
Sbjct: 175 SILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDH--GARHPDMKKRVEDAYILT 232
Query: 240 ANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERI--LKHGIN-------CF 290
N ++ +K ++ S S + ++ AE++ ++++V++I LK +
Sbjct: 233 CNVSLEYEKTEV-NSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVV 291
Query: 291 INRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIE 350
IN++ I + G++A+ A +ERL L GG ++FD LG L+
Sbjct: 292 INQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVY 351
Query: 351 EVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGG 410
E +GE+K + T++++G + L + + ++ D L + + D V G
Sbjct: 352 EYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGA 411
Query: 411 GCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHS 470
G E+ MA A+ + G+ + ++++A AL ++P ++A N+G+D + + +++A HS
Sbjct: 412 GAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS 471
Query: 471 EGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKA 523
E G+D+ G A +G+ +++ VK+Q+L S A IL VD I++A
Sbjct: 472 ESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 524
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 196 bits (498), Expect = 4e-50
Identities = 139/466 (29%), Positives = 243/466 (52%), Gaps = 18/466 (3%)
Query: 74 IGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREA 133
I V +PAAK ++++SR QD+EVGDGTTSV +LA E+L AE + +++HP +I+ +R+A
Sbjct: 32 IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91
Query: 134 TKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLK 191
L +S VD ++ ++NI +++++K ++ +A++AV ++
Sbjct: 92 LDDMISTLKKISIPVDISDSDM-----MLNIINSSITTKAISRWSSLACNIALDAVKMVQ 146
Query: 192 GSGNLEAIHIIKKL-------GGSLADSYLDEGFLLDKKIGVNQPKR-IENAKILIANTG 243
N IKK GG + DS + G +++K + + +R I+N +I++ ++
Sbjct: 147 FEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSS 206
Query: 244 MDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQL 303
++ K + + + + I E+E +++ E I++ + I + I + +
Sbjct: 207 LEYKKGES-QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHY 265
Query: 304 FGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGS-CKLIEEVMIGEDKLIHF 362
A + AI R+A G I S + +G+ L+E IG++
Sbjct: 266 LMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFI 325
Query: 363 SGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVT 422
+ +ACTI+LRGA+++IL E ER+L DA+ V + D + V GGG SEM +AHA+T
Sbjct: 326 TDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALT 385
Query: 423 QLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN-TTAGLDMR 481
+ + G E + A+AL ++P + N G + L+ LRA H++ N T G++
Sbjct: 386 EKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGE 445
Query: 482 EGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527
GT+ DM LGI E VK Q +A E A ++LR+D+I+ +K
Sbjct: 446 TGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 491
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 192 bits (489), Expect = 5e-49
Identities = 137/497 (27%), Positives = 240/497 (48%), Gaps = 12/497 (2%)
Query: 35 IGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDE 94
+ ++ GP GM+K++++ L VTND ATIL+ + V +PAAK++V S +Q+ E
Sbjct: 39 LAQTTRTAYGPNGMNKMVINHLE--KLFVTNDAATILRELEVQHPAAKMIVMASHMQEQE 96
Query: 95 VGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVK 154
VGDGT V V A LL AE L+ + +I G+ A + A E +L + V + ++
Sbjct: 97 VGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHE-ILPNLVCCSAKNLR 155
Query: 155 FRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL---KGSGNLEAIHIIKKLGGSLAD 211
++ ++ T++ SK + KL +A + + G N++ I + K LG ++
Sbjct: 156 DIDEVSSLLRTSIMSKQYGNEV-FLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGISS 214
Query: 212 SYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAE 271
S + G + KK +++AKI + + D + G+ V + + ++ E
Sbjct: 215 SSVLHGMVF-KKETEGDVTSVKDAKIAVYSCPFDGMITETKGT-VLIKTAEELMNFSKGE 272
Query: 272 KEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEI 331
+ M +V+ I G N + + + +M + + RL G
Sbjct: 273 ENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATA 332
Query: 332 ASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVAL-GEACTIVLRGATQQILDEAERSL 390
P L ++G C + +G+ +++ F G TIVLRG+T ++D+ ER++
Sbjct: 333 LPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAV 392
Query: 391 HDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTII 450
D + +D R V GGG +E+ +A +T PG E A++ +A+A +P +
Sbjct: 393 DDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRAL 452
Query: 451 ADNAGYDSADLVAQLRAAHSEGNTTAGLDMRE--GTIGDMAILGITESFQVKRQVLLSAA 508
A+N+G + +++++L A H EGN GLD+ + DM GI +++ K + A
Sbjct: 453 AENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTYLGKYWAIKLAT 512
Query: 509 EAAEVILRVDNIIKAAP 525
AA +LRVD II A P
Sbjct: 513 NAAVTVLRVDQIIMAKP 529
>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
Length = 401
Score = 175 bits (444), Expect = 8e-44
Identities = 123/388 (31%), Positives = 196/388 (50%), Gaps = 23/388 (5%)
Query: 167 LSSKLLTHHKDHFTKLAVEAVLRLKGSG-------NLEAIHIIKKLGGSLADSYLDEGFL 219
+SSK++ + D F + V+AVL +K + + +++I+K G S +S L G+
Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA 60
Query: 220 LDKKIGVN-QPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEK 278
L+ +G PKRI NAKI + + K+K+ G +V + K+ +I E + KE+
Sbjct: 61 LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL-GVQVVITDPEKLDQIRQRESDITKER 119
Query: 279 VERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHP 338
+++IL G N + I + + F AG MA+ ++R+A +G I ST +
Sbjct: 120 IQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANL 179
Query: 339 E------LVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHD 392
E LG + + + I +D+LI + +I+LRGA + DE ERSLHD
Sbjct: 180 EGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHD 239
Query: 393 ALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIAD 452
ALCV+ + ++ V GGG E ++ + A +E +A+ +A++L ++P +A
Sbjct: 240 ALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAV 299
Query: 453 NAGYDSADLVAQLRAAHSEGNTT--------AGLDMREGTIGDMAILGITESFQVKRQVL 504
NA DS DLVA+LRA H+E GLD+ G D G+ E VK + L
Sbjct: 300 NAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSL 359
Query: 505 LSAAEAAEVILRVDNIIKAAPRKRVPDH 532
A EAA ILR+D++IK P + H
Sbjct: 360 KFATEAAITILRIDDLIKLHPESKDDKH 387
>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
sapiens]
Length = 486
Score = 162 bits (410), Expect = 7e-40
Identities = 134/533 (25%), Positives = 243/533 (45%), Gaps = 69/533 (12%)
Query: 6 LAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTN 65
+A V A+ RA+ A + A + D++++ LGPKG K+L+S D L T
Sbjct: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKL--TK 58
Query: 66 DGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQT 125
DG +L +G +HP+
Sbjct: 59 DGNVLLHEMG---------------------------------------------LHPRI 73
Query: 126 IIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
I G+ A + A + L V D R+ L+++A T+L +K+ D T+ V+
Sbjct: 74 ITEGFEAAKEKALQFLEEVKVSREMD----RETLIDVARTSLRTKVHAELADVLTEAVVD 129
Query: 186 AVLRLKGSG---NLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQP---KRIENAKILI 239
++L +K +L I I++ S D+ L G +LD G P KR+E+A IL
Sbjct: 130 SILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDH--GARHPDMKKRVEDAYILT 187
Query: 240 ANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERI--LKHGIN-------CF 290
N ++ +K ++ S S + ++ AE++ ++++V++I LK +
Sbjct: 188 CNVSLEYEKTEV-NSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVV 246
Query: 291 INRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIE 350
IN++ I + G++A+ A +ERL L GG ++FD LG L+
Sbjct: 247 INQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVY 306
Query: 351 EVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGG 410
E +GE+K + T++++G + L + + ++ D L + + D V G
Sbjct: 307 EYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGA 366
Query: 411 GCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHS 470
G E+ MA A+ + G+ + ++++A AL ++P ++A N+G+D + + +++A HS
Sbjct: 367 GAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS 426
Query: 471 EGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKA 523
E G+D+ G A +G+ +++ VK+Q+L S A IL VD I++A
Sbjct: 427 ESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 479
>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
sapiens]
Length = 339
Score = 160 bits (405), Expect = 3e-39
Identities = 93/302 (30%), Positives = 159/302 (52%), Gaps = 2/302 (0%)
Query: 228 QPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGI 287
QPK+ N KI + N ++ K + + +RV + I AE + +K+E+I G
Sbjct: 24 QPKKYHNPKIALLNVELEL-KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGA 82
Query: 288 NCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCK 347
+++ I + Q F + ++R + GG I ++ + LG C+
Sbjct: 83 KVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQ 142
Query: 348 LIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTV 407
+ EE IG ++ F+G + CT +LRG +Q ++E ERSLHDA+ ++ + +K+ V
Sbjct: 143 VFEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVV 202
Query: 408 YGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRA 467
GGG EM ++ + + PGK+ + + +YAKAL ++P + DNAG+D+ +++ +LRA
Sbjct: 203 AGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRA 262
Query: 468 AHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527
H++G T G+D+ I D + E V+ L +A+EAA +I+ VD IK PR
Sbjct: 263 RHAQGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK-NPRS 321
Query: 528 RV 529
V
Sbjct: 322 TV 323
>gi|7657253 T-complex protein 1 [Homo sapiens]
Length = 557
Score = 144 bits (362), Expect = 3e-34
Identities = 129/518 (24%), Positives = 228/518 (44%), Gaps = 19/518 (3%)
Query: 19 ERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDN 78
E E L+S + +++ GP G K L++ + + T IL+ + +++
Sbjct: 27 EEEEPHLLSSLAAVQTLASVIRPCYGPHGRQKFLVTMKGET--VCTGCATAILRALELEH 84
Query: 79 PAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAR 138
PAA +L + + Q + GDGT V +L LL +AE L+ + + + AT
Sbjct: 85 PAAWLLREAGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVL 144
Query: 139 EALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEA---VLRLKGSGN 195
L S A+ L ++ T S + DH TKL A + L GS
Sbjct: 145 ATLPSLAIQSLGPLEDPSWALHSVMNTHTLSPM-----DHLTKLVAHACWAIKELDGSFK 199
Query: 196 LEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSR 255
E + + GG+L DS L G + K+ + A++ + +
Sbjct: 200 PERVGVCALPGGTLEDSCLLPGLAISGKLCGQMATVLSGARVALFACPFGPAHPNA-PAT 258
Query: 256 VRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHA 315
R+ S A +A+ + ++++V ++ GIN + + L G++ I+
Sbjct: 259 ARLSSPADLAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQAR 318
Query: 316 DFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGE-ACTIV 374
+ + L+ V + P+ + G C+ + +G+ + F G A T+V
Sbjct: 319 SWMEIIYLSEVLDTPLLPRLLPPQ--RPGKCQRVYRQELGDGLAVVFEWECTGTPALTVV 376
Query: 375 LRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAV 434
LRGAT Q L AE++++ + Q +D R + G G +EM +A ++ +R G
Sbjct: 377 LRGATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGP 436
Query: 435 AMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGIT 494
A ++A AL+ LP +A+NAG +D++A++ H GN G+ EG I ++A G+
Sbjct: 437 AFLAFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNLLMGVG-TEGII-NVAQEGVW 494
Query: 495 ESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDH 532
++ VK Q + AE ++ VD I+ A K+ P H
Sbjct: 495 DTLIVKAQGFRAVAEVVLQLVTVDEIVVA---KKSPTH 529
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 85.5 bits (210), Expect = 1e-16
Identities = 129/552 (23%), Positives = 230/552 (41%), Gaps = 67/552 (12%)
Query: 13 KAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILK 72
K GAD AR G + D V T+GPKG I+ S S VT DG T+ K
Sbjct: 31 KFGAD------ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSW--GSPKVTKDGVTVAK 82
Query: 73 NIGVD----NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIA 128
+I + N AK++ D++ ++E GDGTT+ TVLA + +E I+K +P I
Sbjct: 83 SIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEI-- 140
Query: 129 GWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLS--SKLLTHHKDHFTKLAVEA 186
R A +A+++ + S V +++ +A + + ++ D K+ +
Sbjct: 141 --RRGVMLAVDAVIAE-LKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKG 197
Query: 187 VLRLKGSGNL-EAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMD 245
V+ +K L + + II+ G Y+ F+ K Q ++A +L++ +
Sbjct: 198 VITVKDGKTLNDELEIIE--GMKFDRGYISPYFINTSK---GQKCEFQDAYVLLSEKKIS 252
Query: 246 TDKIKIFGSRV-RVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIY--NYPEQ 302
+ + + + V E + E + V LK G+ + + N Q
Sbjct: 253 SIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQ 312
Query: 303 L-----------FGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCK---- 347
L FG G+ + V+ L GE+ T D L+K K
Sbjct: 313 LKDMAIATGGAVFGEEGLT----LNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIE 368
Query: 348 -----LIEEVMIG----EDKLIHFSGVALGEACTIVLRGATQQI-LDEAERSLHDALCVL 397
+IE++ + E + ++ L + ++ G T + ++E + + DAL
Sbjct: 369 KRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNAT 428
Query: 398 AQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE--AVAMESYAKALRMLPTIIADNAG 455
V++ V GGGC+ + + L + TP E + +E + L++ IA NAG
Sbjct: 429 RAAVEEG-IVLGGGCA---LLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAG 484
Query: 456 YDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVIL 515
+ + +V ++ + SE G D G +M GI + +V R LL AA A ++
Sbjct: 485 VEGSLIVEKIMQSSSE----VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540
Query: 516 RVDNIIKAAPRK 527
+ ++ P++
Sbjct: 541 TAEVVVTEIPKE 552
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 85.5 bits (210), Expect = 1e-16
Identities = 129/552 (23%), Positives = 230/552 (41%), Gaps = 67/552 (12%)
Query: 13 KAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILK 72
K GAD AR G + D V T+GPKG I+ S S VT DG T+ K
Sbjct: 31 KFGAD------ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSW--GSPKVTKDGVTVAK 82
Query: 73 NIGVD----NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIA 128
+I + N AK++ D++ ++E GDGTT+ TVLA + +E I+K +P I
Sbjct: 83 SIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEI-- 140
Query: 129 GWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLS--SKLLTHHKDHFTKLAVEA 186
R A +A+++ + S V +++ +A + + ++ D K+ +
Sbjct: 141 --RRGVMLAVDAVIAE-LKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKG 197
Query: 187 VLRLKGSGNL-EAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMD 245
V+ +K L + + II+ G Y+ F+ K Q ++A +L++ +
Sbjct: 198 VITVKDGKTLNDELEIIE--GMKFDRGYISPYFINTSK---GQKCEFQDAYVLLSEKKIS 252
Query: 246 TDKIKIFGSRV-RVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIY--NYPEQ 302
+ + + + V E + E + V LK G+ + + N Q
Sbjct: 253 SIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQ 312
Query: 303 L-----------FGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCK---- 347
L FG G+ + V+ L GE+ T D L+K K
Sbjct: 313 LKDMAIATGGAVFGEEGLT----LNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIE 368
Query: 348 -----LIEEVMIG----EDKLIHFSGVALGEACTIVLRGATQQI-LDEAERSLHDALCVL 397
+IE++ + E + ++ L + ++ G T + ++E + + DAL
Sbjct: 369 KRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNAT 428
Query: 398 AQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE--AVAMESYAKALRMLPTIIADNAG 455
V++ V GGGC+ + + L + TP E + +E + L++ IA NAG
Sbjct: 429 RAAVEEG-IVLGGGCA---LLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAG 484
Query: 456 YDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVIL 515
+ + +V ++ + SE G D G +M GI + +V R LL AA A ++
Sbjct: 485 VEGSLIVEKIMQSSSE----VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540
Query: 516 RVDNIIKAAPRK 527
+ ++ P++
Sbjct: 541 TAEVVVTEIPKE 552
>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 48.5 bits (114), Expect = 2e-05
Identities = 84/413 (20%), Positives = 159/413 (38%), Gaps = 36/413 (8%)
Query: 38 LVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGD 97
+V S GP G K L +G + T+ + +L ++ V +P K+L + D
Sbjct: 32 IVTSCYGPSGRLK-QLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSD 90
Query: 98 GTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSA------VDHGSD 151
+L L+ + L + P T+I + L S VD S
Sbjct: 91 CGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSST 147
Query: 152 EVKFRQDLMNIAGTTLSSK----LLTHHKDHFTKLAVEAVL-----RLKGSGNLEAIHII 202
++ L+ + + L+SK L +H + L + A L +G L I+
Sbjct: 148 QI-----LLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIV 202
Query: 203 KKLGGSLADSYLDEGFLLDKK----IGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRV 258
G + DS + G L++ + + K+ K+ + T + D V V
Sbjct: 203 PLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVV 262
Query: 259 DSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFA 318
+E+A +++ +++ ++ + +++I+ +Q ++AI+
Sbjct: 263 SYGVS---LENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVT 319
Query: 319 GVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEA--CTIVLR 376
+E L +TG + + GS K + G HF + EA C+++L
Sbjct: 320 LMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSK---HFFHLIPNEATICSLLLC 376
Query: 377 GATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTP 429
DE + + AL VL T+K+ + GGGC+E +A + + P
Sbjct: 377 NRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDP 429
>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 48.5 bits (114), Expect = 2e-05
Identities = 84/413 (20%), Positives = 159/413 (38%), Gaps = 36/413 (8%)
Query: 38 LVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGD 97
+V S GP G K L +G + T+ + +L ++ V +P K+L + D
Sbjct: 32 IVTSCYGPSGRLK-QLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSD 90
Query: 98 GTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSA------VDHGSD 151
+L L+ + L + P T+I + L S VD S
Sbjct: 91 CGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSST 147
Query: 152 EVKFRQDLMNIAGTTLSSK----LLTHHKDHFTKLAVEAVL-----RLKGSGNLEAIHII 202
++ L+ + + L+SK L +H + L + A L +G L I+
Sbjct: 148 QI-----LLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIV 202
Query: 203 KKLGGSLADSYLDEGFLLDKK----IGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRV 258
G + DS + G L++ + + K+ K+ + T + D V V
Sbjct: 203 PLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVV 262
Query: 259 DSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFA 318
+E+A +++ +++ ++ + +++I+ +Q ++AI+
Sbjct: 263 SYGVS---LENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVT 319
Query: 319 GVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEA--CTIVLR 376
+E L +TG + + GS K + G HF + EA C+++L
Sbjct: 320 LMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSK---HFFHLIPNEATICSLLLC 376
Query: 377 GATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTP 429
DE + + AL VL T+K+ + GGGC+E +A + + P
Sbjct: 377 NRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDP 429
>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
Length = 723
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/414 (18%), Positives = 160/414 (38%), Gaps = 58/414 (14%)
Query: 38 LVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGD 97
+V +GP+G +L + ++++ +G +L+ + +++P A+++VD + GD
Sbjct: 24 IVSCCVGPEGRQ--VLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSSHLKKTGD 81
Query: 98 GTTSVTVLAAELLREAESLIAKKIHP------QTIIAGWREAT--KAAREALLS------ 143
G + + LLR ++ ++ P QT W+ + K +ALL+
Sbjct: 82 GAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFISQALLTFQTQIL 141
Query: 144 -------------SAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL 190
S + R L + ++ ++ ++L + +
Sbjct: 142 DGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKFISQLMCDYFFKC 201
Query: 191 ----KGSGNLEAI--HIIKK----LGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA 240
G G E + H ++ G ++DS + G +L K V +P + +++
Sbjct: 202 MTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLVLQKDFSVYRPADGDMRMVIVT 261
Query: 241 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP 300
T GS ++S A+ + EK K ++ + + I+ P
Sbjct: 262 ETIQPL--FSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKHLHSQNVKLLISS---VKQP 316
Query: 301 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHP------ELVKLGSCKLIEEVMI 354
+ + AGV I + E ++L+ S F P E+ K + +++
Sbjct: 317 DLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQCEIPNTALVKFCKPLIL 376
Query: 355 GEDKLIHFSGVALGEAC-----TIVLRGATQQILDEAERSLHDALCVLAQTVKD 403
+ +H + L C +IVL G ++++ E +LH AL +L Q KD
Sbjct: 377 RSKRYVH---LGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKMLRQLFKD 427
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 41.6 bits (96), Expect = 0.002
Identities = 49/206 (23%), Positives = 86/206 (41%), Gaps = 16/206 (7%)
Query: 199 IHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKR-IENAKILIANTGMDTDKIKIFGSRVR 257
+HI K GG DS + GF+ K I + I+N KIL+ ++ + R
Sbjct: 665 VHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIE------YLYREE 718
Query: 258 VDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADF 317
T + I E+E +K V+RI+ + + + + + G+ + +
Sbjct: 719 TKFTC-IDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKS 777
Query: 318 AGVERLALVTGGEIASTFDHPELVK--LGSC-----KLIEEVMIGEDKLIHFSGVALGEA 370
+ER++ +T G++ + D L K LG+C ++ + L+ F G
Sbjct: 778 QVLERISRMTQGDLVMSMDQL-LTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLG 836
Query: 371 CTIVLRGATQQILDEAERSLHDALCV 396
CTI LRG + L + L +CV
Sbjct: 837 CTIKLRGGSDYELARVKEILIFMICV 862
>gi|109638749 signal recognition particle 72kDa [Homo sapiens]
Length = 671
Score = 31.6 bits (70), Expect = 1.9
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Query: 169 SKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQ 228
+K+L +KD T L + V ++ EA+++I LA++ L +K +
Sbjct: 35 NKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLS----FEKAYCEYR 90
Query: 229 PKRIENAKILIANTGMDTDKIK 250
RIENA I + TDK+K
Sbjct: 91 LNRIENALKTIESANQQTDKLK 112
>gi|153082755 interferon-induced protein with tetratricopeptide
repeats 2 [Homo sapiens]
Length = 472
Score = 30.8 bits (68), Expect = 3.2
Identities = 51/228 (22%), Positives = 85/228 (37%), Gaps = 34/228 (14%)
Query: 77 DNPAAKVLVDMS----RVQDDEVGDGTTSVTVL------AAELLREAESLIAKKIHPQTI 126
DN KVL+ + R + +E G+G V ++LR A +K P
Sbjct: 207 DNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKA 266
Query: 127 IAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEA 186
I E K A E + ++A H +R + + + + K +L A
Sbjct: 267 I----ELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGM---YGKRKLLELIGHA 319
Query: 187 VLRLK----GSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIG------VNQPKRIENAK 236
V LK + NL + I +LAD Y D + K+ Q +
Sbjct: 320 VAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLHLRYGN 379
Query: 237 ILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILK 284
+ + I F V+++ ++ EKEKMK+K+++I K
Sbjct: 380 FQLYQMKCEDKAIHHFIEGVKINQKSR-------EKEKMKDKLQKIAK 420
>gi|4502163 apolipoprotein D precursor [Homo sapiens]
Length = 189
Score = 30.0 bits (66), Expect = 5.5
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 11/93 (11%)
Query: 182 LAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIG-----VNQPKRIENAK 236
L + A+ L G+ +A H+ G + + E F ++K +G P EN +
Sbjct: 6 LLLSALAGLFGAAEGQAFHL-----GKCPNPPVQENFDVNKYLGRWYEIEKIPTTFENGR 60
Query: 237 ILIANTG-MDTDKIKIFGSRVRVDSTAKVAEIE 268
+ AN M+ KIK+ +R D T E E
Sbjct: 61 CIQANYSLMENGKIKVLNQELRADGTVNQIEGE 93
>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 29.6 bits (65), Expect = 7.2
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 252 FGSRVRVDSTAKVAEIEHAEKEK------MKEKVERILKHGINCFINRQLIYNYPEQLFG 305
FGS V S AK +E + +K + +E++ K G++ ++ N EQLFG
Sbjct: 553 FGSYV--PSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFG 610
Query: 306 AAGVMAI 312
A+G I
Sbjct: 611 ASGSSTI 617
>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 29.6 bits (65), Expect = 7.2
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 252 FGSRVRVDSTAKVAEIEHAEKEK------MKEKVERILKHGINCFINRQLIYNYPEQLFG 305
FGS V S AK +E + +K + +E++ K G++ ++ N EQLFG
Sbjct: 553 FGSYV--PSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFG 610
Query: 306 AAGVMAI 312
A+G I
Sbjct: 611 ASGSSTI 617
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,632,156
Number of Sequences: 37866
Number of extensions: 637609
Number of successful extensions: 1802
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1736
Number of HSP's gapped (non-prelim): 30
length of query: 535
length of database: 18,247,518
effective HSP length: 107
effective length of query: 428
effective length of database: 14,195,856
effective search space: 6075826368
effective search space used: 6075826368
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.